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Nock, Berthold A; Charalambidis, David; Sallegger, Werner; Waser, Beatrice; Mansi, Rosalba; Nicolas, Guillaume P; Ketani, Eleni; Nikolopoulou, Anastasia; Fani, Melpomeni; Reubi, Jean-Claude; Maina, Theodosia (2018). New Gastrin Releasing Peptide Receptor-Directed [Tc]Demobesin 1 Mimics: Synthesis and Comparative Evaluation. Journal of medicinal chemistry, 61(7), pp. 3138-3150. American Chemical Society 10.1021/acs.jmedchem.8b00177
Gourni, Eleni; Del Pozzo, Luigi; Kheirallah, Emilie; Smerling, Christiane; Waser, Beatrice; Reubi, Jean-Claude; Paterson, Brett M; Donnelly, Paul S; Meyer, Philipp T; Maecke, Helmut R (2015). Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer. Molecular Pharmaceutics, 12(8), pp. 2781-2790. American Chemical Society 10.1021/mp500671j
Reubi, Jean-Claude (2014). Strict rules are needed for validation of G-protein-coupled receptor immunohistochemical studies in human tissues. Endocrine, 47(3), pp. 659-661. Springer 10.1007/s12020-014-0320-0
Gourni, Eleni; Mansi, Rosalba; Jamous, Mazen; Waser, Beatrice; Smerling, Christiane; Burian, Antje; Buchegger, Franz; Reubi, Jean-Claude; Maecke, Helmut R (2014). N-terminal modifications improve the receptor affinity and pharmacokinetics of radiolabeled peptidic gastrin-releasing peptide receptor antagonists: examples of 68Ga- and 64Cu-labeled peptides for PET imaging. Journal of nuclear medicine, 55(10), pp. 1719-1725. Society of Nuclear Medicine 10.2967/jnumed.114.141242
Waser, Beatrice; Blank, Annika; Karamitopoulou, Evanthia; Perren, Aurel; Reubi, Jean-Claude (2014). Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas. Modern pathology, 28(3), pp. 391-402. Nature Publishing Group 10.1038/modpathol.2014.113
Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Tatsi, Aikaterini; Kaloudi, Aikaterini; Krenning, Eric P; de Jong, Marion; Nock, Berthold A; Reubi, Jean-Claude (2014). [111In-DOTA]LTT-SS28, a first pansomatostatin radioligand for in vivo targeting of somatostatin receptor-positive tumors. Journal of medicinal chemistry, 57(15), pp. 6564-6571. American Chemical Society 10.1021/jm500581d
Jamous, Mazen; Tamma, Maria L; Gourni, Eleni; Waser, Beatrice; Reubi, Jean-Claude; Maecke, Helmut R; Mansi, Rosalba (2014). PEG spacers of different length influence the biological profile of bombesin-based radiolabeled antagonists. Nuclear medicine and biology, 41(6), pp. 464-470. Elsevier 10.1016/j.nucmedbio.2014.03.014
Wild, Damian; Fani, Melpomeni; Fischer, Richard; Del Pozzo, Luigi; Kaul, Felix; Krebs, Simone; Fischer, Richard; Rivier, Jean E F; Reubi, Jean-Claude; Maecke, Helmut R; Weber, Wolfgang A (2014). Comparison of Somatostatin Receptor Agonist and Antagonist for Peptide Receptor Radionuclide Therapy: A Pilot Study. Journal of nuclear medicine, 55(8), pp. 1248-1252. Society of Nuclear Medicine 10.2967/jnumed.114.138834
Waser, Beatrice; Reubi, Jean-Claude (2014). Radiolabelled GLP-1 receptor antagonist binds to GLP-1 receptor-expressing human tissues. European journal of nuclear medicine and molecular imaging, 41(6), pp. 1166-1171. Springer 10.1007/s00259-013-2684-4
Gourni, Eleni; Waser, Beatrice; Clerc, Pascal; Fourmy, Daniel; Reubi, Jean-Claude; Maecke, Helmut R (2014). The Glucose-Dependent Insulinotropic Polypeptide Receptor: A Novel Target for Neuroendocrine Tumor Imaging-First Preclinical Studies. Journal of nuclear medicine, 55(6), pp. 976-982. Society of Nuclear Medicine 10.2967/jnumed.113.133744
Mikkola, Kirsi; Yim, Cheng-Bin; Fagerholm, Veronica; Ishizu, Tamiko; Elomaa, Viki-Veikko; Rajander, Johan; Jurttila, Jori; Saanijoki, Tiina; Tolvanen, Tuula; Tirri, Marko; Gourni, Eleni; Béhé, Martin; Gotthardt, Martin; Reubi, Jean-Claude; Mäcke, Helmut; Roivainen, Anne; Solin, Olof; Nuutila, Pirjo (2014). Erratum to: (64)Cu- and (68)Ga-Labelled [Nle (14),Lys (40)(Ahx-NODAGA)NH 2]-Exendin-4 for Pancreatic Beta Cell Imaging in Rats. Molecular imaging and biology, 16(2), p. 293. Springer 10.1007/s11307-013-0700-5
Mikkola, Kirsi; Kirsi, Mikkola; Yim, Cheng-Bin; Cheng-Bin, Yim; Fagerholm, Veronica; Veronica, Fagerholm; Ishizu, Tamiko; Tamiko, Ishizu; Elomaa, Viki-Veikko; Viki-Veikko, Elomaa; Rajander, Johan; Johan, Rajander; Jurttila, Jori; Jori, Jurttila; Saanijoki, Tiina; Tiina, Saanijoki; Tolvanen, Tuula; Tuula, Tolvanen; Tirri, Marko; Marko, Tirri; ... (2014). 64Cu- and 68Ga-labelled [Nle(14),Lys(40)(Ahx-NODAGA)NH2]-exendin-4 for pancreatic beta cell imaging in rats. Molecular imaging and biology, 16(2), pp. 255-263. Springer 10.1007/s11307-013-0691-2
Tatsi, Aikaterini; Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Krenning, Eric P; de Jong, Marion; Cordopatis, Paul; Reubi, Jean-Claude; Nock, Berthold A (2014). [DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting. European journal of medicinal chemistry, 73, pp. 30-37. Elsevier Masson SAS 10.1016/j.ejmech.2013.12.003
Körner Jachertz, Meike; Waser, Beatrice; Rehmann, Ruth; Reubi, Jean-Claude (2014). Early over-expression of GRP receptors in prostatic carcinogenesis. Prostate, 74(2), pp. 217-224. Wiley-Blackwell 10.1002/pros.22743
Komor, Jan; Reubi, Jean-Claude; Christ, Emanuel R. (2014). Peptide receptor radionuclide therapy in a patient with disabling non-functioning pituitary adenoma. Pituitary, 17(3), pp. 227-231. Springer Science + Business Media 10.1007/s11102-013-0494-0
Wieser, Gesche; Mansi, Rosalba; Grosu, Anca L; Schultze-Seemann, Wolfgang; Dumont-Walter, Rebecca A; Meyer, Philipp T; Maecke, Helmut R; Reubi, Jean-Claude; Weber, Wolfgang A (2014). Positron emission tomography (PET) imaging of prostate cancer with a gastrin releasing peptide receptor antagonist - from mice to men. Theranostics, 4(4), pp. 412-419. Ivyspring International 10.7150/thno.7324
Wicki, Andreas; Wild, Damian; Prêtre, Vincent; Mansi, Rosalba; Orleth, Annette; Reubi, Jean-Claude; Rochlitz, Christoph; Mamot, Christoph; Mäcke, Helmut R; Christofori, Gerhard (2014). Synergism of peptide receptor-targeted Auger electron radiation therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors. EJNMMI research, 4(1), p. 9. Springer 10.1186/2191-219X-4-9
Reubi, Jean-Claude; Schonbrunn, Agnes (2013). Illuminating somatostatin analog action at neuroendocrine tumor receptors. Trends in Pharmacological Sciences, 34(12), pp. 676-688. Elsevier 10.1016/j.tips.2013.10.001
Sparr, Christof; Purkayastha, Nirupam; Yoshinari, Tomohiro; Seebach, Dieter; Maschauer, Simone; Prante, Olaf; Hübner, Harald; Gmeiner, Peter; Kolesinska, Beata; Cescato, Renzo; Waser, Beatrice; Reubi, Jean-Claude (2013). Syntheses, receptor bindings, in vitro and in vivo stabilities and biodistributions of DOTA-neurotensin(8-13) derivatives containing β-amino acid residues - a lesson about the importance of animal experiments. Chemistry & Biodiversity, 10(12), pp. 2101-2121. Verlag Helvetica Chimica Acta 10.1002/cbdv.201300331
Christ, Emanuel; Wild, Damian; Ederer, Susanne; Béhé, Martin; Nicolas, Guillaume; Caplin, Martyn E.; Brändle, Michael; Clerici, Thomas; Fischli, Stefan; Stettler, Christoph; Ell, Peter J.; Seufert, Jochen; Gloor, Beat; Perren, Aurel; Reubi, Jean-Claude; Forrer, Flavio (2013). Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study. The lancet. Diabetes & endocrinology, 1(2), pp. 115-122. Elsevier 10.1016/S2213-8587(13)70049-4
Dumont, Rebecca A.; Tamma, MariaLuisa; Braun, Friederike; Borkowski, Sandra; Reubi, Jean-Claude; Maecke, Helmut; Weber, Wolfgang A.; Mansi, Rosalba (2013). Targeted radiotherapy of prostate cancer with a gastrin-releasing peptide receptor antagonist is effective as monotherapy and in combination with rapamycin. Journal of nuclear medicine, 54(5), pp. 762-769. Society of Nuclear Medicine 10.2967/jnumed.112.112169
Mansi, Rosalba; Fleischmann, Achim; Mäcke, Helmut R.; Reubi, Jean-Claude (2013). Targeting GRPR in urological cancers--from basic research to clinical application. Nature Reviews. Urology, 10(4), pp. 235-244. Nature Publishing Group 10.1038/nrurol.2013.42
Wild, Damian; Bomanji, Jamshed B.; Benkert, Pascal; Maecke, Helmut; Ell, Peter J.; Reubi, Jean-Claude; Caplin, Martyn E. (2013). Comparison of 68Ga-DOTANOC and 68Ga-DOTATATE PET/CT within patients with gastroenteropancreatic neuroendocrine tumors. Journal of nuclear medicine, 54(3), pp. 364-372. Society of Nuclear Medicine 10.2967/jnumed.112.111724
Waser, Beatrice; Rehmann, Ruth; Sanchez, Claire; Fourmy, Daniel; Reubi, Jean-Claude (2012). Glucose-dependent insulinotropic polypeptide receptors in most gastroenteropancreatic and bronchial neuroendocrine tumors. Journal of clinical endocrinology and metabolism, 97(2), pp. 482-8. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2011-2454
Sanchez, Claire; Escrieut, Chantal; Clerc, Pascal; Gigoux, Véronique; Waser, Beatrice; Reubi, Jean-Claude; Fourmy, Daniel (2012). Characterization of a novel five-transmembrane domain cholecystokinin-2 receptor splice variant identified in human tumors. Molecular and cellular endocrinology, 349(2), pp. 170-9. Shannon: Elsevier Ireland 10.1016/j.mce.2011.10.010
von Guggenberg, Elisabeth; Rangger, Christine; Sosabowski, Jane; Laverman, Peter; Reubi, Jean-Claude; Virgolini, Irene Johanna; Decristoforo, Clemens (2012). Preclinical Evaluation of Radiolabeled DOTA-Derivatized Cyclic Minigastrin Analogs for Targeting Cholecystokinin Receptor Expressing Malignancies. Molecular imaging and biology, 14(3), pp. 366-75. New York, N.Y.: Springer 10.1007/s11307-011-0506-2
Win, Thida; Screaton, Nicholas J; Porter, Joanna; Endozo, Raymondo; Wild, Damian; Kayani, Irfan; Dickson, John; Shortman, Robert I; Reubi, Jean-Claude; Ell, Peter J; Groves, Ashley M (2012). Novel positron emission tomography/computed tomography of diffuse parenchymal lung disease combining a labeled somatostatin receptor analogue and 2-deoxy-2[¹⁸F]fluoro-D-glucose. Molecular imaging, 11(2), pp. 91-8. Hamilton, Ont.: Decker 10.1097/00005382-199621000-00001
Waser, Beatrice; Cescato, Renzo; Liu, Qisheng; Kao, Yachu J; Körner, Meike; Christ, Emanuel; Schonbrunn, Agnes; Reubi, Jean-Claude (2012). Phosphorylation of sst2 receptors in neuroendocrine tumors after octreotide treatment of patients. American journal of pathology, 180(5), pp. 1942-9. New York, N.Y.: Elsevier 10.1016/j.ajpath.2012.01.041
Körner, Meike; Rehmann, Ruth; Reubi, Jean-Claude (2012). GLP-2 receptors in human disease: high expression in gastrointestinal stromal tumors and Crohn's disease. Molecular and cellular endocrinology, 364(1-2), pp. 46-53. Shannon: Elsevier Ireland 10.1016/j.mce.2012.08.008
Zhang, Hanwen; Abiraj, Keelara; Thorek, Daniel L. J.; Waser, Beatrice; Smith-Jones, Peter M.; Honer, Michael; Reubi, Jean-Claude; Maecke, Helmut R. (2012). Evolution of bombesin conjugates for targeted PET imaging of tumors. PLoS ONE, 7(9), e44046. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0044046
Nock, Berthold A; Cescato, Renzo; Ketani, Eleni; Waser, Beatrice; Reubi, Jean-Claude; Maina, Theodosia (2012). [(99m)Tc]Demomedin C, a radioligand based on human gastrin releasing peptide(18-27): synthesis and preclinical evaluation in gastrin releasing peptide receptor-expressing models. Journal of medicinal chemistry, 55(19), pp. 8364-74. Easton, Pa.: American Chemical Society 10.1021/jm300741f
Wang, Xuejuan; Fani, Melpomeni; Schulz, Stefan; Rivier, Jean; Reubi, Jean-Claude; Maecke, Helmut R (2012). Comprehensive evaluation of a somatostatin-based radiolabelled antagonist for diagnostic imaging and radionuclide therapy. European journal of nuclear medicine and molecular imaging, 39(12), pp. 1876-85. Berlin: Springer 10.1007/s00259-012-2231-8
Fani, Melpomeni; Braun, Friederike; Waser, Beatrice; Beetschen, Karin; Cescato, Renzo; Erchegyi, Judit; Rivier, Jean E; Weber, Wolfgang A; Maecke, Helmut R; Reubi, Jean-Claude (2012). Unexpected sensitivity of sst2 antagonists to N-terminal radiometal modifications. Journal of nuclear medicine, 53(9), pp. 1481-9. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.112.102764
Lee, Misu; Waser, Beatrice; Reubi, Jean-Claude; Pellegata, Natalia S (2012). Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway. Molecular endocrinology, 26(8), pp. 1394-405. Bethesda, Md.: Endocrine Society 10.1210/me.2012-1055
Tatsi, Aikaterini; Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Krenning, Eric P; de Jong, Marion; Cordopatis, Paul; Reubi, Jean-Claude; Nock, Berthold A (2012). [111In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study. EJNMMI research, 2(1), p. 25. Berlin: Springer 10.1186/2191-219X-2-25
Allen, Camryn D; Waser, Beatrice; Körner, Meike; Reubi, Jean-Claude; Lee, Soon; Rivier, Catherine (2011). Neuropeptide Y acts within the rat testis to inhibit testosterone secretion. Neuropeptides, 45(1), pp. 55-61. Amsterdam: Elsevier 10.1016/j.npep.2010.10.006
Mansi, Rosalba; Wang, Xuejuan; Forrer, Flavio; Waser, Beatrice; Cescato, Renzo; Graham, Keith; Borkowski, Sandra; Reubi, Jean-Claude; Maecke, Helmut R (2011). Development of a potent DOTA-conjugated bombesin antagonist for targeting GRPr-positive tumours. European journal of nuclear medicine and molecular imaging, 38(1), pp. 97-107. Berlin: Springer 10.1007/s00259-010-1596-9
Zueger, Thomas; Buehler, Annette; Stalder, Mario; Walpoth, Nazan; Reubi, Jean-Claude; Stettler, Christoph (2011). A rare localization of a neuroendocrine tumor. Journal of clinical endocrinology and metabolism, 96(6), pp. 1625-6. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2011-0124
Reubi, Jean-Claude; Fleischmann, Achim; Waser, Beatrice; Rehmann, Ruth (2011). Concomitant vascular GRP-receptor and VEGF-receptor expression in human tumors: molecular basis for dual targeting of tumoral vasculature. Peptides, 32(7), pp. 1457-62. New York, N.Y.: Elsevier 10.1016/j.peptides.2011.05.007
Körner, Meike; Waser, Beatriche; Thalmann, George N; Reubi, Jean-Claude (2011). High expression of NPY receptors in the human testis. Molecular and cellular endocrinology, 337(1-2), pp. 62-70. Shannon: Elsevier Ireland 10.1016/j.mce.2011.01.021
Chatenet, David; Cescato, Renzo; Waser, Beatrice; Erchegyi, Judit; Rivier, Jean E; Reubi, Jean-Claude (2011). Novel dimeric DOTA-coupled peptidic Y1-receptor antagonists for targeting of neuropeptide Y receptor-expressing cancers. European journal of nuclear medicine and molecular imaging, 1(1), p. 21. Berlin: Springer 10.1186/2191-219X-1-21
Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria-Luisa; Fani, Melpomeni; Forrer, Flavio; Nicolas, Guillaume; Cescato, Renzo; Reubi, Jean-Claude; Maecke, Helmut R (2011). Bombesin antagonist-based radioligands for translational nuclear imaging of gastrin-releasing peptide receptor-positive tumors. Journal of nuclear medicine, 52(12), pp. 1970-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.094375
Cescato, Renzo; Waser, Beatrice; Fani, Melpomeni; Reubi, Jean-Claude (2011). Evaluation of 177Lu-DOTA-sst2 antagonist versus 177Lu-DOTA-sst2 agonist binding in human cancers in vitro. Journal of nuclear medicine, 52(12), pp. 1886-90. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.095778
Wild, Damian; Fani, Melpomeni; Behe, Martin; Brink, Ingo; Rivier, Jean E F; Reubi, Jean-Claude; Maecke, Helmut R; Weber, Wolfgang A (2011). First clinical evidence that imaging with somatostatin receptor antagonists is feasible. Journal of nuclear medicine, 52(9), pp. 1412-7. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.088922
Erchegyi, Judit; Cescato, Renzo; Waser, Beatrice; Rivier, Jean E; Reubi, Jean-Claude (2011). N-imidazolebenzyl-histidine substitution in somatostatin and in its octapeptide analogue modulates receptor selectivity and function. Journal of medicinal chemistry, 54(17), pp. 5981-7. Easton, Pa.: American Chemical Society 10.1021/jm200307v
Fani, Melpomeni; Del Pozzo, Luigi; Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria Luisa; Cescato, Renzo; Waser, Beatrice; Weber, Wolfgang A; Reubi, Jean-Claude; Maecke, Helmut R (2011). PET of somatostatin receptor-positive tumors using 64Cu- and 68Ga-somatostatin antagonists: the chelate makes the difference. Journal of nuclear medicine, 52(7), pp. 1110-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.087999
Maecke, Helmut R; Reubi, Jean-Claude (2011). Somatostatin receptors as targets for nuclear medicine imaging and radionuclide treatment. Journal of nuclear medicine, 52(6), pp. 841-4. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.084236
Seebach, Dieter; Lukaszuk, Aneta; Patora-Komisarska, Krystyna; Podwysocka, Dominika; Gardiner, James; Ebert, Marc-Olivier; Reubi, Jean-Claude; Cescato, Renzo; Waser, Beatrice; Gmeiner, Peter; Hübner, Harald; Rougeot, Catherine (2011). On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum--neurotensin, opiorphin, B27-KK10 epitope, NPY. Chemistry & Biodiversity, 8(5), pp. 711-39. Zürich: Verlag Helvetica Chimica Acta 10.1002/cbdv.201100093
Ocak, Meltem; Helbok, Anna; Rangger, Christine; Peitl, Petra Kolenc; Nock, Berthold A; Morelli, Giancarlo; Eek, Annemarie; Sosabowski, Jane K; Breeman, Wout A P; Reubi, Jean-Claude; Decristoforo, Clemens (2011). Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1426-35. Berlin: Springer 10.1007/s00259-011-1818-9
Aloj, Luigi; Aurilio, Michela; Rinaldi, Valentina; D'ambrosio, Laura; Tesauro, Diego; Peitl, Petra Kolenc; Maina, Theodosia; Mansi, Rosalba; von Guggenberg, Elisabeth; Joosten, Lieke; Sosabowski, Jane K; Breeman, Wouter A P; De Blois, Erik; Koelewijn, Stuart; Melis, Marleen; Waser, Beatrice; Beetschen, Karin; Reubi, Jean-Claude; de Jong, Marion (2011). Comparison of the binding and internalization properties of 12 DOTA-coupled and ¹¹¹In-labelled CCK2/gastrin receptor binding peptides: a collaborative project under COST Action BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1417-25. Berlin: Springer 10.1007/s00259-011-1816-y
Laverman, Peter; Joosten, Lieke; Eek, Annemarie; Roosenburg, Susan; Peitl, Petra Kolenc; Maina, Theodosia; Mäcke, Helmut; Aloj, Luigi; von Guggenberg, Elisabeth; Sosabowski, Jane K; de Jong, Marion; Reubi, Jean-Claude; Oyen, Wim J G; Boerman, Otto C (2011). Comparative biodistribution of 12 ¹¹¹In-labelled gastrin/CCK2 receptor-targeting peptides. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1410-6. Berlin: Springer 10.1007/s00259-011-1806-0
Kolenc-Peitl, Petra; Mansi, Rosalba; Tamma, MariaLuisa; Gmeiner-Stopar, Tanja; Sollner-Dolenc, Marija; Waser, Beatrice; Baum, Richard P; Reubi, Jean-Claude; Maecke, Helmut R (2011). Highly improved metabolic stability and pharmacokinetics of indium-111-DOTA-gastrin conjugates for targeting of the gastrin receptor. Journal of medicinal chemistry, 54(8), pp. 2602-9. Easton, Pa.: American Chemical Society 10.1021/jm101279a
Wild, Damian; Frischknecht, Michael; Zhang, Hanwen; Morgenstern, Alfred; Bruchertseifer, Frank; Boisclair, Julie; Provencher-Bolliger, Anne; Reubi, Jean-Claude; Maecke, Helmut R (2011). Alpha- versus beta-particle radiopeptide therapy in a human prostate cancer model (213Bi-DOTA-PESIN and 213Bi-AMBA versus 177Lu-DOTA-PESIN). Cancer research, 71(3), pp. 1009-18. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-1186
Waser, Beatrice; Reubi, Jean-Claude (2011). Value of the radiolabelled GLP-1 receptor antagonist exendin(9-39) for targeting of GLP-1 receptor-expressing pancreatic tissues in mice and humans. European journal of nuclear medicine and molecular imaging, 38(6), pp. 1054-8. Berlin: Springer-Verlag 10.1007/s00259-010-1701-0
Körner, Meike; Waser, Beatrice; Reubi, Jean-Claude; Miller, Laurence J. (2010). CCK2 receptor splice variant with intron 4 retention in human gastrointestinal and lung tumours. Journal of Cellular and Molecular Medicine, 14(4), pp. 933-943. Bucharest (Romania): Wiley 10.1111/j.1582-4934.2009.00859.x
Reubi, Jean-Claude; Waser, Beatrice; Cescato, Renzo; Gloor, Beat; Stettler, Christoph; Christ, Emanuel (2010). Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients. Journal of clinical endocrinology and metabolism, 95(5), pp. 2343-50. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-2487
Fani, Melpomeni; Mueller, Andreas; Tamma, Maria-Luisa; Nicolas, Guillaume; Rink, Hans R; Cescato, Renzo; Reubi, Jean-Claude; Maecke, Helmut R (2010). Radiolabeled bicyclic somatostatin-based analogs: a novel class of potential radiotracers for SPECT/PET of neuroendocrine tumors. Journal of nuclear medicine, 51(11), pp. 1771-9. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.076695
Waser, Beatrice; Cescato, Renzo; Tamma, Maria-Luisa; Maecke, Helmut R; Reubi, Jean-Claude (2010). Absence of somatostatin SST(2) receptor internalization in vivo after intravenous SOM230 application in the AR42J animal tumor model. European journal of pharmacology, 644(1-3), pp. 257-62. Amsterdam: Elsevier 10.1016/j.ejphar.2010.07.005
Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria-Luisa; Forrer, Flavio; Cescato, Renzo; Reubi, Jean-Claude; Akyel, Kayhan G; Maecke, Helmut R (2010). Tetraamine-derived bifunctional chelators for technetium-99m labelling: synthesis, bioconjugation and evaluation as targeted SPECT imaging probes for GRP-receptor-positive tumours. Chemistry - a European journal, 16(7), pp. 2115-24. Weinheim: Wiley-VCH 10.1002/chem.200902011
Cescato, Renzo; Loesch, Kimberly A; Waser, Beatrice; Mäcke, Helmut R; Rivier, Jean E; Reubi, Jean-Claude; Schonbrunn, Agnes (2010). Agonist-biased signaling at the sst2A receptor: the multi-somatostatin analogs KE108 and SOM230 activate and antagonize distinct signaling pathways. Molecular endocrinology, 24(1), pp. 240-9. Bethesda, Md.: Endocrine Society 10.1210/me.2009-0321
Christ, Emanuel; Wild, Damian; Reubi, Jean-Claude (2010). Glucagonlike peptide-1 receptor: an example of translational research in insulinomas: a review. Endocrinology and metabolism clinics of North America, 39(4), pp. 791-800. Philadelphia, Pa.: Elsevier 10.1016/j.ecl.2010.09.003
Shastry, Manu; Kayani, Irfan; Wild, Damian; Caplin, Martyn; Visvikis, Dimitris; Gacinovic, Svetislav; Reubi, Jean-Claude; Bomanji, Jamshed B (2010). Distribution pattern of 68Ga-DOTATATE in disease-free patients. Nuclear medicine communications, 31(12), pp. 1025-32. London: Lippincott Williams & Wilkins 10.1097/MNM.0b013e32833f635e
Di Cianni, Alessandra; Carotenuto, Alfonso; Brancaccio, Diego; Novellino, Ettore; Reubi, Jean-Claude; Beetschen, Karin; Papini, Anna Maria; Ginanneschi, Mauro (2010). Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. Journal of medicinal chemistry, 53(16), pp. 6188-97. Easton, Pa.: American Chemical Society 10.1021/jm1005868
Oberg, Kjell E; Reubi, Jean-Claude; Kwekkeboom, Dik J; Krenning, Eric P (2010). Role of somatostatins in gastroenteropancreatic neuroendocrine tumor development and therapy. Gastroenterology, 139(3), 742-53, 753.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2010.07.002
Wild, Damian; Theodoraki, Aikaterini; Kurzawinski, Tom R; Bomanji, Jamshed; Reubi, Jean-Claude; Khan, Rehman; Bouloux, Pierre; Khoo, Bernard (2010). 'Running on empty'. European journal of nuclear medicine and molecular imaging, 37(7), pp. 1439-40. Berlin: Springer 10.1007/s00259-010-1455-8
Wa ngler, Carmen; Waser, Beatrice; Alke, Andrea; Iovkova, Ljuba; Buchholz, Hans-Georg; Niedermoser, Sabrina; Jurkschat, Klaus; Fottner, Christian; Bartenstein, Peter; Schirrmacher, Ralf; Reubi, Jean-Claude; Wester, Hans-Ju rgen; Wa ngler, Bjo rn (2010). One-Step (18)F-Labeling of Carbohydrate-Conjugated Octreotate-Derivatives Containing a Silicon-Fluoride-Acceptor (SiFA): In Vitro and in Vivo Evaluation as Tumor Imaging Agents for Positron Emission Tomography (PET). Bioconjugate chemistry, 21(12), pp. 2289-96. Washington, D.C.: American Chemical Society 10.1021/bc100316c
Christ, Emanuel; Wild, Damian; Forrer, Flavio; Brändle, Michael; Sahli, Rahel; Clerici, Thomas; Gloor, Beat; Martius, Ferdinand; Maecke, Helmut; Reubi, Jean-Claude (2009). Glucagon-like peptide-1 receptor imaging for localization of insulinomas. Journal of clinical endocrinology and metabolism, 94(11), pp. 4398-405. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-1082
Mansi, Rosalba; Wang, Xuejuan; Forrer, Flavio; Kneifel, Stefan; Tamma, Maria-Luisa; Waser, Beatrice; Cescato, Renzo; Reubi, Jean-Claude; Maecke, Helmut R (2009). Evaluation of a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated bombesin-based radioantagonist for the labeling with single-photon emission computed tomography, positron emission tomography, and therapeutic radionuclides. Clinical cancer research, 15(16), pp. 5240-9. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-3145
Fleischmann, Achim; Waser, Beatrice; Reubi, Jean-Claude (2009). High expression of gastrin-releasing peptide receptors in the vascular bed of urinary tract cancers: promising candidates for vascular targeting applications. Endocrine-related cancer, 16(2), pp. 623-33. Bristol: BioScientifica Ltd. 10.1677/ERC-08-0316
Waser, Bea; Tamma, Maria-Luisa; Cescato, Renzo; Maecke, Helmut R; Reubi, Jean-Claude (2009). Highly efficient in vivo agonist-induced internalization of sst2 receptors in somatostatin target tissues. Journal of nuclear medicine, 50(6), pp. 936-41. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.108.061457
Beierle, John M; Horne, W Seth; van Maarseveen, Jan H; Waser, Beatrice; Reubi, Jean-Claude; Ghadiri, M Reza (2009). Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues. Angewandte Chemie (International ed.), 48(26), pp. 4725-9. Weinheim: Wiley-VCH 10.1002/anie.200805901
Erchegyi, Judit; Cescato, Renzo; Grace, Christy Rani R; Waser, Beatrice; Piccand, Véronique; Hoyer, Daniel; Riek, Roland; Rivier, Jean E; Reubi, Jean-Claude (2009). Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. Journal of medicinal chemistry, 52(9), pp. 2733-46. Easton, Pa.: American Chemical Society 10.1021/jm801314f
Akgün, Eyup; Körner Jachertz, Meike; Gao, Fan; Harikumar, Kaleeckal G; Waser, Beatrice; Reubi, Jean-Claude; Portoghese, Philip S; Miller, Laurence J (2009). Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and type 2 cholecystokinin receptors. Journal of medicinal chemistry, 52(7), pp. 2138-47. Easton, Pa.: American Chemical Society 10.1021/jm801439x
Feytens, Debby; De Vlaeminck, Magali; Cescato, Renzo; Tourwé, Dirk; Reubi, Jean-Claude (2009). Highly potent 4-amino-indolo[2,3-c]azepin-3-one-containing somatostatin mimetics with a range of sst receptor selectivities. Journal of medicinal chemistry, 52(1), pp. 95-104. Easton, Pa.: American Chemical Society 10.1021/jm801205x
Reubi, Jean-Claude; Maecke, Helmut R (2008). Peptide-based probes for cancer imaging. Journal of nuclear medicine, 49(11), pp. 1735-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.108.053041
Wild, Damian; Mäcke, Helmut; Christ, Emanuel; Gloor, Beat; Reubi, Jean-Claude (2008). Glucagon-like peptide 1-receptor scans to localize occult insulinomas. New England journal of medicine NEJM, 359(7), pp. 766-8. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMc0802045
Körner, Meike; Waser, Beatrice; Reubi, Jean-Claude (2008). High expression of neuropeptide Y1 receptors in ewing sarcoma tumors. Clinical cancer research, 14(16), pp. 5043-9. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-07-4551
Palii, Stela S; Afzal, Aqeela; Shaw, Lynn C; Pan, Hao; Caballero, Sergio; Miller, Rehae C; Jurczyk, Simona; Reubi, Jean-Claude; Tan, Yufei; Hochhaus, Guenther; Edelhauser, Henry; Geroski, Dayle; Shapiro, Gideon; Grant, Maria B (2008). Nonpeptide somatostatin receptor agonists specifically target ocular neovascularization via the somatostatin type 2 receptor. Investigative ophthalmology & visual science, 49(11), pp. 5094-102. Hagerstown, Md.: Association for Research in Vision and Ophthalmology 10.1167/iovs.08-2289
Good, Stephan; Walter, Martin A; Waser, Beatrice; Wang, Xuejuan; Müller-Brand, Jan; Béhé, Martin P; Reubi, Jean-Claude; Maecke, Helmut R (2008). Macrocyclic chelator-coupled gastrin-based radiopharmaceuticals for targeting of gastrin receptor-expressing tumours. European journal of nuclear medicine and molecular imaging, 35(10), pp. 1868-77. Berlin: Springer 10.1007/s00259-008-0803-4
Heppeler, Axel; André, João P; Buschmann, Ingeborg; Wang, Xuejuan; Reubi, Jean-Claude; Hennig, Michael; Kaden, Thomas A; Maecke, Helmut R (2008). Metal-ion-dependent biological properties of a chelator-derived somatostatin analogue for tumour targeting. Chemistry - a European journal, 14(10), pp. 3026-34. Weinheim: Wiley-VCH 10.1002/chem.200701264
Wicki, Andreas; Wild, Damian; Storch, Daniel; Seemayer, Christian; Gotthardt, Martin; Behe, Martin; Kneifel, Stefan; Mihatsch, Michael J; Reubi, Jean-Claude; Mäcke, Helmut R; Christofori, Gerhard (2007). [Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 is a highly efficient radiotherapeutic for glucagon-like peptide-1 receptor-targeted therapy for insulinoma. Clinical cancer research, 13(12), pp. 3696-705. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-06-2965
Antunes, Patricia; Ginj, Mihaela; Walter, Martin A; Chen, Jianhua; Reubi, Jean-Claude; Maecke, Helmut R (2007). Influence of different spacers on the biological profile of a DOTA-somatostatin analogue. Bioconjugate chemistry, 18(1), pp. 84-92. Washington, D.C.: American Chemical Society 10.1021/bc0601673
Storch, D; Schmitt, JS; Waldherr, C; Waser, B; Reubi, Jean-Claude; Maecke, HR (2007). Preclinical evaluation of somatostatin analogs bearing two macrocyclic chelators for high specific activity labeling with radiometals. Radiochimica acta, 95(6), pp. 359-69. München: Oldenbourg 10.1524/ract.2007.95.6.359
Ginj, Mihaela; Schmitt, Jörg S; Chen, Jianhua; Waser, Beatrice; Reubi, Jean-Claude; de Jong, Marion; Schulz, Stefan; Maecke, Helmut R (2006). Design, synthesis, and biological evaluation of somatostatin-based radiopeptides. Chemistry & biology, 13(10), pp. 1081-90. San Francisco, Calif.: Current Biology Ltd. 10.1016/j.chembiol.2006.08.012
Lebtahi, Rachida; Moreau, Severine; Marchand-Adam, Sylvain; Debray, Marie-Pierre; Brauner, Michel; Soler, Paul; Marchal, Joëlle; Raguin, Olivier; Gruaz-Guyon, Anne; Reubi, Jean-Claude; Le Guludec, Dominique; Crestani, Bruno (2006). Increased uptake of 111In-octreotide in idiopathic pulmonary fibrosis. Journal of nuclear medicine, 47(8), pp. 1281-7. New York, N.Y.: Society of Nuclear Medicine
Nock, Berthold A; Nikolopoulou, Anastasia; Reubi, Jean-Claude; Maes, Veronique; Conrath, Peter; Tourwé, Dirk; Maina, Theodosia (2006). Toward stable N4-modified neurotensins for NTS1-receptor-targeted tumor imaging with 99mTc. Journal of medicinal chemistry, 49(15), pp. 4767-76. Easton, Pa.: American Chemical Society 10.1021/jm060415g
Maina, Theodosia; Nock, Berthold A; Cordopatis, Paul; Bernard, Bert F; Breeman, Wout A P; van Gameren, Arthur; van den Berg, Ria; Reubi, Jean-Claude; Krenning, Eric P; de Jong, Marion (2006). [(99m)Tc]Demotate 2 in the detection of sst(2)-positive tumours: a preclinical comparison with [(111)In]DOTA-tate. European journal of nuclear medicine and molecular imaging, 33(7), pp. 831-40. Berlin: Springer 10.1007/s00259-006-0068-8
Reubi, Jean-Claude; Körner Jachertz, Meike; Waser, Beatrice; Mazzucchelli, Luca; Guillou, Louis (2004). High expression of peptide receptors as a novel target in gastrointestinal stromal tumours. European journal of nuclear medicine and molecular imaging, 31(6), pp. 803-810. Springer-Verlag 10.1007/s00259-004-1476-2
Reubi, Jean-Claude; Gugger, Mathias; Waser, Beatrice (2002). Co-expressed peptide receptors in breast cancer as a molecular basis for in vivo multireceptor tumour targeting. European journal of nuclear medicine and molecular imaging, 29(7), pp. 855-862. Springer-Verlag 10.1007/s00259-002-0794-5
Reubi, Jean-Claude (1997). Relevance of somatostatin receptors and other peptide receptors in pathology. Endocrine pathology, 8(1), pp. 11-20. Springer 10.1007/BF02739703
Anderson, B; Reubi, Jean-Claude; Waser, Beatrice (1979). Labor contracts and negotiations. NLN publications(52-1805), pp. 69-74.
Körner Jachertz, Meike; Reubi, Jean-Claude (2013). Somatostatin/NPY. In: Kastin, Abba J. (ed.) Handbook of Biologically Active Peptides, 2nd ed. (pp. 548-555). Amsterdam: Elsevier
