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Blatter, Tobias Ueli; Nakas, Christos Theodoros; Leichtle, Alexander Benedikt (2024). Direct, age- and gender-specific reference intervals: applying a modified M-estimator of the Yeo-Johnson transformation to clinical real-world data. Journal of Laboratory Medicine De Gruyter 10.1515/labmed-2024-0076
Blatter, Tobias Ueli; Witte, Harald; Fasquelle-Lopez, Jules; Raisaro, Jean Louis; Leichtle, Alexander Benedikt (2023). The BioRef Infrastructure, a Framework for Real-Time, Federated, Privacy-Preserving, and Personalized Reference Intervals: Design, Development, and Application. Journal of medical internet research, 25(e47254), e47254. JMIR Publications 10.2196/47254
Nagabhushana, Priyanka; Rütsche, Cyrill; Nakas, Christos; Leichtle, Alexander B. (2023). Deployment of an Automated Method Verification-Graphical User Interface (MV-GUI) Software. BioMedInformatics, 3(3), pp. 632-648. MDPI 10.3390/biomedinformatics3030043
Buttia, Chepkoech; Llanaj, Erand; Raeisi-Dehkordi, Hamidreza; Kastrati, Lum; Amiri, Mojgan; Meçani, Renald; Taneri, Petek Eylul; Gomez Ochoa, Sergio Alejandro; Raguindin, Peter Francis; Wehrli, Faina; Khatami, Farnaz; Pano Espinola, Octavio; Rojas, Lyda Z; de Mortanges, Aurélie Pahud; Macharia-Nimietz, Eric Francis; Alijla, Fadi; Minder, Beatrice; Leichtle, Alexander B; Lüthi, Nora; Ehrhard, Simone; ... (2023). Prognostic models in COVID-19 infection that predict severity: a systematic review. European journal of epidemiology, 38(4), pp. 355-372. Springer 10.1007/s10654-023-00973-x
Mottin, Luc; Goldman, Jean-Philippe; Jäggli, Christoph; Achermann, Rita; Gobeill, Julien; Knafou, Julien; Ehrsam, Julien; Wicky, Alexandre; Gérard, Camille L; Schwenk, Tanja; Charrier, Mélinda; Tsantoulis, Petros; Lovis, Christian; Leichtle, Alexander; Kiessling, Michael K; Michielin, Olivier; Pradervand, Sylvain; Foufi, Vasiliki; Ruch, Patrick (2023). Multilingual RECIST classification of radiology reports using supervised learning. Frontiers in digital health, 5(1195017), p. 1195017. Frontiers Media 10.3389/fdgth.2023.1195017
Sokollik, Christiane; Pahud de Mortanges, Aurélie; Leichtle, Alexander B.; Juillerat, Pascal; Horn, Michael (2023). Machine Learning in Antibody Diagnostics for Inflammatory Bowel Disease Subtype Classification. Diagnostics, 13(15), p. 2491. MDPI 10.3390/diagnostics13152491
Witte, Harald; Blatter, Tobias U.; Nagabhushana, Priyanka; Schär, David; Ackermann, James; Cadamuro, Janne; Leichtle, Alexander B. (2023). Statistical learning and big data applications. Journal of Laboratory Medicine, 47(4), pp. 181-186. De Gruyter 10.1515/labmed-2023-0037
Boehl, Gabriela; Raguindin, Peter Francis; Valido, Ezra; Bertolo, Alessandro; Itodo, Oche Adam; Minder, Beatrice; Lampart, Patricia; Scheel-Sailer, Anke; Leichtle, Alexander; Glisic, Marija; Stoyanov, Jivko (2022). Endocrinological and inflammatory markers in individuals with spinal cord injury: A systematic review and meta-analysis. Reviews in endocrine and metabolic disorders, 23(5), pp. 1035-1050. Springer 10.1007/s11154-022-09742-9
Franchini, Filippo; Kusejko, Katharina; Marzolini, Catia; Tellenbach, Christoph; Rossi, Simona; Stampf, Susanne; Koller, Michael; Stoyanov, Jivko; Möller, Burkhard; Leichtle, Alexander Benedikt (2022). Collaborative challenges of multi-cohort project in pharmacogenetics - why time is essential for meaningful collaborations [viewpoint]. JMIR formative research, 6(9), e36759. JMIR Publications 10.2196/36759
Witte, Harald; Nakas, Christos Theodoros; Bally, Lia; Leichtle, Alexander Benedikt (2022). Machine-learning Prediction of Hypo- and Hyperglycemia from Electronic Health Records: Algorithm Development and Validation. JMIR formative research, 6(7), e36176. JMIR Publications 10.2196/36176
Magyar, Benjamin P; Santi, Maristella; Sommer, Grit; Nuoffer, Jean-Marc; Leichtle, Alexander; Grössl, Michael; Fluck, Christa E (2022). Short-Term Fasting Attenuates Overall Steroid Hormone Biosynthesis in Healthy Young Women. Journal of the Endocrine Society, 6(7), bvac075. Oxford University Press 10.1210/jendso/bvac075
Müller, Martin; Sägesser, Nadine; Keller, Peter M; Arampatzis, Spyridon; Steffens, Benedict; Ehrhard, Simone; Leichtle, Alexander B (2022). Urine Flow Cytometry Parameter Cannot Safely Predict Contamination of Urine-A Cohort Study of a Swiss Emergency Department Using Machine Learning Techniques. Diagnostics, 12(4) MDPI 10.3390/diagnostics12041008
Atkinson, A.; Ellenberger, B; Piezzi, V.; Kaspar, T.; Endrich, O.; Leichtle, A.B.; Zwahlen, M.; Marschall, J. (2022). A Bayesian spatial-temporal model for prevalence estimation of a VRE outbreak in a tertiary care hospital. Journal of hospital infection, 122, pp. 108-114. Elsevier 10.1016/j.jhin.2021.12.024
Blatter, Tobias Ueli; Witte, Harald; Nakas, Christos Theodoros; Leichtle, Alexander Benedikt (2022). Big Data in Laboratory Medicine—FAIR Quality for AI? Diagnostics, 12(8), p. 1923. MDPI 10.3390/diagnostics12081923
Musy, Sarah N; Endrich, Olga; Leichtle, Alexander B; Griffiths, Peter; Nakas, Christos T.; Simon, Michael (2021). The association between nurse staffing and inpatient mortality: A shift-level retrospective longitudinal study. International journal of nursing studies, 120, p. 103950. Elsevier 10.1016/j.ijnurstu.2021.103950
Arnold, Markus; Schweizer, Juliane; Nakas, Christos T; Schütz, Valerie; Westphal, Laura P; Inauen, Corinne; Pokorny, Thomas; Luft, Andreas; Leichtle, Alexander; Arnold, Marcel; Bicvic, Antonela; Fischer, Urs; De Marchis, Gian Marco; Bonati, Leo H; Müller, Mandy D; Kahles, Timo; Nedeltchev, Krassen; Cereda, Carlo W; Kägi, Georg; Bustamante, Alejandro; ... (2021). Lipoprotein(a) is associated with large artery atherosclerosis stroke aetiology and stroke recurrence among patients below the age of 60 years: results from the BIOSIGNAL study. European heart journal, 42(22), pp. 2186-2196. Oxford University Press 10.1093/eurheartj/ehab081
Maurer, Martin H.; Brönnimann, Michael; Schroeder, Christophe; Ghadamgahi, Ehssan; Streitparth, Florian; Heverhagen, Johannes T.; Leichtle, Alexander; de Bucourt, Maximilian; Meyl, Tobias Philipp (2021). Time Requirement and Feasibility of a Systematic Quality Peer Review of Reporting in Radiology. RöFo. Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 193(2), pp. 160-167. Thieme 10.1055/a-1178-1113
Kohl Schwartz, A.S.; Burkard, S; Mitter, V.R.; Leichtle, A.B.; Fink, A.; von Wolff, M. (2020). Short-term application of ibuprofen before ovulation. Facts, views & vision in ObGyn, 12(3), pp. 179-184. Flemish Society of Obstetrics & Gynaecology
Freiburghaus, Katrin; Leichtle, Alexander Benedikt; Nakas, Christos T.; Fiedler, Georg M.; Largiadèr, Carlo R. (2020). Effects of Freezing and Thawing Procedures on Selected Clinical Chemistry Parameters in Plasma. Biopreservation and biobanking, 18(4), pp. 297-304. Liebert 10.1089/bio.2020.0005
Kim, Soung Yung; Wittwer, M; Funke-Chambour, Manuela; Leichtle, Alexander Benedikt; Berezowska, Sabina Anna; Geiser, Thomas; Heverhagen, Johannes; Pöllinger, Alexander (July 2020). Increased expiratory CT Density reveals possible abnormalities in radiologically preserved lung parenchyma in idiopathic pulmonary fibrosis, hypersensitivity pneumonitis and systemic sclerosis (Unpublished). In: ECR 2020, Vienna.
Raisaro, Jean Louis; Troncoso-Pastoriza, Juan Ramòn; Pradervand, Sylvain; Cuendet, Michel; Misbach, Mickael; Sa, Joao; Marino, Francesco; Freundler, Nicolas; Rosat, Nicolas; Cavin, David; Leichtle, Alexander; Fellay, Jacques; Michielin, Olivier; Hubaux, Jean-Pierre (2020). SPHN/PHRT - MedCo in Action: Empowering the Swiss Molecular Tumor Board with Privacy-Preserving and Real-Time Patient Discovery. Studies in health technology and informatics, 270, pp. 1161-1162. IOS Press 10.3233/SHTI200345
Arnold, Markus; Nakas, Christos; Luft, Andreas; Christ-Crain, Mirjam; Leichtle, Alexander; Katan, Mira (2020). Independent Prognostic Value of MRproANP (Midregional Proatrial Natriuretic Peptide) Levels in Patients With Stroke Is Unaltered Over Time. Stroke, 51(6), pp. 1873-1875. American Heart Association 10.1161/STROKEAHA.120.029333
Musy, Sarah N; Endrich, Olga; Leichtle, Alexander B; Griffiths, Peter; Nakas, Christos T; Simon, Michael (2020). Longitudinal Study of the Variation in Patient Turnover and Patient-to-Nurse Ratio: Descriptive Analysis of a Swiss University Hospital. Journal of medical internet research, 22(4), e15554. JMIR Publications 10.2196/15554
Dhayat, Nasser A.; Pruijm, Menno; Ponte, Belen; Ackermann, Daniel; Leichtle, Alexander Benedikt; Devuyst, Olivier; Ehret, Georg; Guessous, Idris; Pechère-Bertschi, Antoinette; Pastor, Johanne; Martin, Pierre-Yves; Burnier, Michel; Fiedler, Georg-Martin; Vogt, Bruno; Moe, Orson; Bochud, Murielle; Fuster, Daniel G. (2020). Parathyroid hormone and plasma phosphate are predictors of soluble α-klotho levels in adults of European descent. The journal of clinical endocrinology and metabolism, 105(4), e1135-e1143. Oxford University Press 10.1210/clinem/dgz232
Schefold, Joerg C.; Gerber, Joël L.; Angehrn, Michelle C.; Müller, Martin; Messmer, Anna S.; Leichtle, Alexander B.; Fiedler, Georg M.; Exadaktylos, Aristomenis; Pfortmüller, Carmen (2020). Renal Function-Adjusted D-Dimer Levels in Critically Ill Patients With Suspected Thromboembolism. Critical care medicine, 48(4), e270-e276. Wolters Kluwer Health 10.1097/CCM.0000000000004204
Rindlisbacher, Barbara; Schild, Christof; Egger, Florence; Bacher, Vera U.; Pabst, Thomas; Leichtle, Alexander; Andres, Martin; Sédille-Mostafaie, Nazanin (2020). Serum Free Light Chain Assay: Shift Toward a Higher κ/λ Ratio. The journal of applied laboratory medicine, 5(1), pp. 114-125. Oxford University Press 10.1093/jalm.2019.029330
Diem, Lara; Bürge, Maxine; Leichtle, Alexander; Hakim, Arsany; Chan, Andrew; Salmen, Anke; Evangelopoulos, Maria-Eleptheria; Hoepner, Robert (2020). Pathological cerebrospinal fluid protein concentration and albumin quotient at relapse predicts short-term disability progression in multiple sclerosis: a retrospective single center observational study. Therapeutic advances in neurological disorders, 13, p. 175628642097590. Sage 10.1177/1756286420975909
Wolfensberger, Nathan; Georgiou, Georgios; Giabbani, Evelyne; Reusser, Marianne; Njue, Linet M.; Fiedler, Martin; Leichtle, Alexander B.; Nagler, Michael (2019). Rapid Centrifugation in the Routine Hemostasis Laboratory. Thrombosis and haemostasis, 119(12), pp. 2025-2033. Thieme 10.1055/s-0039-1696712
Müller, Martin; Schefold, Joerg C.; Leichtle, Alexander Benedikt; Srivastava, David Shiva; Lindner, G; Exadaktylos, Aristomenis K.; Pfortmüller, Carmen (2019). qSOFA score not predictive of in-hospital mortality in emergency patients with decompensated liver cirrhosis. Medizinische Klinik, Intensivmedizin und Notfallmedizin, 114(8), pp. 724-732. Springer 10.1007/s00063-018-0477-z
Egli-Spichtig, Daniela; Imenez Silva, Pedro Henrique; Glaudemans, Bob; Gehring, Nicole; Bettoni, Carla; Zhang, Martin Y H; Pastor-Arroyo, Eva M; Schönenberger, Désirée; Rajski, Michal; Hoogewijs, David; Knauf, Felix; Misselwitz, Benjamin; Frey-Wagner, Isabelle; Rogler, Gerhard; Ackermann, Daniel; Ponte, Belen; Pruijm, Menno; Leichtle, Alexander; Fiedler, Georg-Martin; Bochud, Murielle; ... (2019). Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation. Kidney international, 96(4), pp. 890-905. Elsevier 10.1016/j.kint.2019.04.009
Franco-Pereira, Alba M; Nakas, Christos T.; Leichtle, Alexander Benedikt; Pardo, M Carmen (2019). Bootstrap-based testing approaches for the assessment of the diagnostic accuracy of biomarkers subject to a limit of detection. Statistical Methods in Medical Research, 28(5), pp. 1564-1578. SAGE Publications (UK and US) 10.1177/0962280218769334
Kim, Soung Yung; Wittwer, M; Funke, M; Leichtle, Alexander Benedikt; Berezowska, Sabina Anna; Geiser, Thomas; Heverhagen, Johannes; Pöllinger, Alexander (May 2019). Increased expiratorycomputed tomography density reveals possible abnormalities in radiologically preserved lung parenchyma in idiopathic pulmonary fibrosis, hypersensivity Pneumonitis and systemic sclerosis (Unpublished). In: ESTI, Paris.
Schütz, Narayan; Leichtle, Alexander Benedikt; Riesen, Kaspar (2019). A comparative study of pattern recognition algorithms for predicting the inpatient mortality risk using routine laboratory measurements. Artificial intelligence review, 52(4), pp. 2559-2573. Springer 10.1007/s10462-018-9625-3
Scholz, Godehard A.; Leichtle, Alexander B.; Scherer, Almut; Arndt, Uta; Fiedler, Martin; Aeberli, Daniel; Finckh, Axel; Gabay, Cem; Kyburz, Diego; Villiger, Peter M.; Möller, Burkhard (2019). The links of hepcidin and erythropoietin in the interplay of inflammation and iron deficiency in a large observational study of rheumatoid arthritis. British journal of haematology, 186(1), pp. 101-112. Wiley-Blackwell 10.1111/bjh.15895
Schuh, Sabine K.; Seidenberg, Ruth; Arampatzis, Spyridon; Leichtle, Alexander B.; Hautz, Wolf E.; Exadaktylos, Aristomenis K.; Schechter, Clyde B; Müller, Martin (2019). Diagnosis of Urinary Tract Infections by Urine Flow Cytometry: Adjusted Cut-Off Values in Different Clinical Presentations. Disease markers, 2019(5853486), p. 5853486. Hindawi 10.1155/2019/5853486
Walder, Anna; Müller, Martin; Dahdal, Suzan; Sidler, Daniel; Devetzis, Vasilios; Leichtle, Alexander B.; Fiedler, Martin G.; Popp, Albrecht; Lippuner, Kurt; Vogt, Bruno; Uehlinger, Dominik; Huynh-Do, Uyen; Arampatzis, Spyridon (2018). The effect of a previous created distal arteriovenous-fistula on radial bone DXA measurements in prevalent renal transplant recipients. PLoS ONE, 13(7), e0200708. Public Library of Science 10.1371/journal.pone.0200708
Horn, Michael; Peter, Anna Maria; Righini Grunder, Franziska; Leichtle, Alexander Benedikt; Spalinger, Johannes; Schibli, Susanne; Sokollik, Christiane (2018). PR3-ANCA and panel diagnostics in pediatric inflammatory bowel disease to distinguish ulcerative colitis from Crohn's disease. PLoS ONE, 13(12), e0208974. Public Library of Science 10.1371/journal.pone.0208974
Lesche, Dorothea; Sigurdardottir, Vilborg; Leichtle, Alexander Benedikt; Nakas, Christos T.; Christians, Uwe; Englberger, Lars; Fiedler, Georg Martin; Largiadèr, Carlo Rodolfo; Mohacsi, Paul; Sistonen, Johanna (2018). Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement. Metabolomics, 14(1), p. 3. Springer 10.1007/s11306-017-1294-8
Dahlweid, Fried-Michael; Kämpf, Matthias; Leichtle, Alexander (2018). Interoperability of laboratory data in Switzerland – a spotlight on Bern. LaboratoriumsMedizin / Journal of laboratory medicine, 42(6), pp. 251-258. Walter de Gruyter 10.1515/labmed-2018-0072
Findeisen, P.; Zahn, I.; Fiedler, Georg Martin; Leichtle, Alexander Benedikt; Wang, S.; Soria, G.; Johnson, P.; Henzell, J.; Hegel, J.K.; Bendavid, C.; Collet, N.; McGovern, M.; Klopprogge, K. (2018). Doubling immunochemistry laboratory testing efficiency with the cobas e 801 module while maintaining consistency in analytical performance. Clinical biochemistry, 58, pp. 86-93. Elsevier 10.1016/j.clinbiochem.2018.05.019
Cadamuro, Janne; Mrazek, Cornelia; Leichtle, Alexander Benedikt; Kipman, Ulrike; Felder, Thomas K.; Wiedemann, Helmut; Oberkofler, Hannes; Fiedler, Georg Martin; Haschke-Becher, Elisabeth (2018). Influence of centrifugation conditions on the results of 77 routine clinical chemistry analytes using standard vacuum blood collection tubes and the new BD-Barricor tubes. Biochemia Medica, 28(1), 010704. Croatian Society of Medical Biochemistry and Laboratory Medicine 10.11613/BM.2018.010704
Müller, Martin; Seidenberg, Ruth; Schuh, Sabine K.; Exadaktylos, Aristomenis; Schechter, Clyde B.; Leichtle, Alexander B.; Hautz, Wolf (2018). The development and validation of different decision-making tools to predict urine culture growth out of urine flow cytometry parameter. PLoS ONE, 13(2), e0193255. Public Library of Science 10.1371/journal.pone.0193255
Rindlisbacher, Barbara; Strebel, Carina; Guler, Sabina; Kollár, Attila; Geiser, Thomas; Fiedler, Georg Martin; Leichtle, Alexander Benedikt; Bovet, Cédric; Funke-Chambour, Manuela (2017). Exhaled breath condensate as a potential biomarker tool for idiopathic pulmonary fibrosis - a pilot study. Journal of breath research, 12(1), 016003. IOP Science 10.1088/1752-7163/aa840a
Haider, Dominik; Klemenz, Thomas; Fiedler, Georg Martin; Nakas, Christos T.; Exadaktylos, Aristomenis; Leichtle, Alexander Benedikt (2017). In response to the letter to the editor on our manuscript "High sensitive cardiac troponin T: Testing the test" by Dr. Badertscher. International journal of cardiology, 234, p. 127. Elsevier 10.1016/j.ijcard.2017.01.114
Conrad, Tim O F; Genzel, Martin; Cvetkovic, Nada; Wulkow, Niklas; Leichtle, Alexander Benedikt; Vybiral, Jan; Kutyniok, Gitta; Schütte, Christof (2017). Sparse Proteomics Analysis - a compressed sensing-based approach for feature selection and classification of high-dimensional proteomics mass spectrometry data. BMC bioinformatics, 18(1), p. 160. BioMed Central 10.1186/s12859-017-1565-4
Pfortmueller, Carmen A; Lindner, Gregor; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christoph; Exadaktylos, Aristomenis (2017). Role of D-Dimer testing in venous thromboembolism with concomitant renal insufficiency in critical care. Intensive care medicine, 43(3), pp. 470-471. Springer 10.1007/s00134-016-4646-3
Haider, Dominik; Klemenz, Thomas; Fiedler, Martin; Nakas, Christos T.; Exadaktylos, Aristomenis; Leichtle, Alexander Benedikt (2017). High sensitive cardiac troponin T: Testing the test. International journal of cardiology, 228, pp. 779-783. Elsevier 10.1016/j.ijcard.2016.10.043
Zinkernagel, Martin; Zysset-Burri, Denise Corinne; Keller, Irene; Berger, Lieselotte Erika; Leichtle, Alexander Benedikt; Largiadèr, Carlo Rodolfo; Fiedler, Martin; Wolf, Sebastian (2017). Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration. Scientific Reports, 7(40826), p. 40826. Nature Publishing Group 10.1038/srep40826
Müller, Martin; Guignard, Viviane; Schefold, Joerg C.; Leichtle, Alexander Benedikt; Exadaktylos, Aristomenis; Pfortmüller, Carmen (2017). Utility of quick sepsis-related organ failure assessment (qSOFA) to predict outcome in patients with pneumonia. PLoS ONE, 12(12), e0188913. Public Library of Science 10.1371/journal.pone.0188913
von Meyer, Alexander; Cadamuro, Janne; Streichert, Thomas; Gurr, Eberhard; Fiedler, Georg Martin; Leichtle, Alexander Benedikt; Petersmann, Astrid; Pick, Karl-Heinz; Orth, Matthias; Risch, Lorenz; Sonntag, Oswald; Schmitt, York; Wiegel, Bernhard; Töpfer, Gottfried; Guder, Walter G. (2017). Standard-Arbeitsanleitung zur peripher venösen Blutentnahme für die labormedizinische Diagnostik. LaboratoriumsMedizin / Journal of laboratory medicine, 41(6), pp. 333-340. De Gruyter 10.1515/labmed-2017-0127
Bally, Lia; Bovet, Cédric; Nakas, Christos T.; Zueger, Thomas; Prost, Jean-Christophe; Nuoffer, Jean-Marc; Leichtle, Alexander Benedikt; Fiedler, Georg Martin; Stettler, Christoph (2017). A metabolomics approach to uncover effects of different exercise modalities in type 1 diabetes. Metabolomics, 13(7) Springer 10.1007/s11306-017-1217-8
Sauter, Thomas; Ziegenhorn, Stephan; Ahmad, Sufian; Hautz, Wolf; Ricklin, Meret; Leichtle, Alexander Benedikt; Fiedler, Martin; Haider, Dominik; Exadaktylos, Aristomenis (2016). Age is not associated with intracranial haemorrhage in patients with mild traumatic brain injury and oral anticoagulation. Journal of negative results in biomedicine, 15(1), p. 12. BioMed Central 10.1186/s12952-016-0055-y
Dhayat, Nasser; Ackermann, Daniel; Pruijm, Menno; Ponte, Belen; Ehret, Georg; Guessous, Idris; Leichtle, Alexander Benedikt; Paccaud, Fred; Mohaupt, Markus; Fiedler, Martin; Devuyst, Olivier; Pechère-Bertschi, Antoinette; Burnier, Michel; Martin, Pierre-Yves; Bochud, Murielle; Vogt, Bruno; Fuster, Daniel Guido (2016). Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function. Kidney international, 90(3), pp. 648-657. Elsevier 10.1016/j.kint.2016.04.024
Haider, Dominik; Lindner, Gregor; Wolzt, Michael; Leichtle, Alexander Benedikt; Fiedler, Martin; Sauter, Thomas; Fuhrmann, Valentin; Exadaktylos, Aristomenis (2016). Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study. Journal of negative results in biomedicine, 15(1), p. 1. BioMed Central 10.1186/s12952-016-0044-1
Pichler Hefti, Jacqueline Renée; Leichtle, Alexander Benedikt; Stutz, Monika; Hefti, Urs; Geiser, Thomas; Huber, Andreas R; Merz, Tobias Michael (2016). Increased endothelial microparticles and oxidative stress at extreme altitude. European journal of applied physiology, 116(4), pp. 739-748. Springer 10.1007/s00421-015-3309-3
Pfortmueller, Carmen Andrea; Drexel, Christian; Krähenmann-Müller, Simone; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2016). S-100 B Concentrations Are a Predictor of Decreased Survival in Patients with Major Trauma, Independently of Head Injury. PLoS ONE, 11(3), e0152822. Public Library of Science 10.1371/journal.pone.0152822
Nakas, Christos T.; Schütz, Narayan; Werners, Marcus; Leichtle, Alexander Benedikt (2016). Accuracy and Calibration of Computational Approaches for Inpatient Mortality Predictive Modeling. PLoS ONE, 11(7), e0159046. Public Library of Science 10.1371/journal.pone.0159046
Bally, Lia; Züger, Thomas; Stettler, Christoph; Leichtle, Alexander Benedikt (2016). Computed exercise plasma lactate concentrations: A conversion formula. Practical Laboratory Medicine, 4, pp. 11-15. Elsevier 10.1016/j.plabm.2015.11.002
Lesche, Dorothea; Geyer, Roland; Lienhard, Daniel; Nakas, Christos T.; Diserens, Gaëlle; Vermathen, Peter; Leichtle, Alexander Benedikt (2016). Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome. Metabolomics, 12(10), p. 159. Springer 10.1007/s11306-016-1109-3
Studer, Martina; Goeggel Simonetti, Barbara; Heinks Maldonado, Theda; Steinlin, Maja; Leichtle, Alexander Benedikt; Berger, Steffen Michael; Joeris, Alexander (2015). Acute S100B in serum is associated with cognitive symptoms and memory performance 4 months after paediatric mild traumatic brain injury. Brain injury, 29(13-14), pp. 1667-1673. Informa Healthcare 10.3109/02699052.2015.1075250
Lindner, G; Heldner, Mirjam Rachel; Bernasconi, Corrado Angelo; Funk, G C; Arnold, Marcel; Schwarz, C; Leichtle, Alexander Benedikt; Fiedler, Martin; Gralla, Jan; Mattle, Heinrich; Exadaktylos, Aristomenis; Fischer, Urs (2015). Prevalence of dysnatremias and their implication on outcome during acute ischemic stroke and transient ischemic attack: A cross-sectional analysis. International journal of stroke, 10(Suppl 2), p. 241. Blackwell Publishing
Haider, Dominik; Lindner, Gregor; Ahmad, Sufian; Sauter, Thomas; Wolzt, Michael; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Fuhrmann, Valentin (2015). Hypermagnesemia is a strong independent risk factor for mortality in critically ill patients: results from a cross-sectional study. European journal of internal medicine, 26(7), pp. 504-507. Pozzi 10.1016/j.ejim.2015.05.013
Leichtle, Alexander Benedikt; Findeisen, Peter (2015). 7.7 Biobanking. In: Guder, Walter G.; Narayanan, Sheshadri (eds.) Pre-examination Procedures in Laboratory Diagnostics. Preanalytical Aspects and their Impact on the Quality of Medical Laboratory Results (pp. 328-334). Berlin: De Gruyter 10.1515/9783110334043-038
Sauter, Thomas; Lindner, Gregor; Ahmad, Sufian; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Haider, Dominik (2015). Calcium Disorders in the Emergency Department: Independent Risk Factors for Mortality. PLoS ONE, 10(7), e0132788. Public Library of Science 10.1371/journal.pone.0132788
Pfortmüller, Carmen; Pauchard-Neuwerth, Sandra Elisabeth; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Lindner, Gregor (2015). Primary Hyperventilation in the Emergency Department: A First Overview. PLoS ONE, 10(6), e0129562. Public Library of Science 10.1371/journal.pone.0129562
Pfortmüller, Carmen; Drexel, C; Krähenmann-Müller, S; Leichtle, Alexander Benedikt; Fiedler, Martin; Lindner, G; Exadaktylos, AK (2015). S-100 B Concentrations Are a Predictor of Decreased Survival in Patients With Major Trauma Independently of Head Injury. Intensive care medicine experimental, 3(Suppl 1), A31. Springer 10.1186/2197-425X-3-S1-A31
Leichtle, Alexander Benedikt (2015). Biomarker – vom Sein und Wesen. LaboratoriumsMedizin / Journal of laboratory medicine, 39(2), pp. 97-101. De Gruyter 10.1515/labmed-2015-0033
Haider, Dominik; Lindner, Gregor; Wolzt, Michael; Ahmad, Sufian S; Sauter, Thomas; Leichtle, Alexander Benedikt; Fiedler, Georg-Martin; Fuhrmann, Valentin; Exadaktylos, Aristomenis (2015). Hyperphosphatemia Is an Independent Risk Factor for Mortality in Critically Ill Patients: Results from a Cross-Sectional Study. PLoS ONE, 10(8), e0133426. Public Library of Science 10.1371/journal.pone.0133426
Lindner, G; Funk, G-C; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christa; Eleftheriadis, T; Pasch, Andreas; Mohaupt, Markus; Exadaktylos, Aristomenis; Arampatzis, Spyridon (2014). Impact of proton pump inhibitor use on magnesium homoeostasis: a cross-sectional study in a tertiary emergency department. International Journal of Clinical Practice, 68(11), pp. 1352-1357. Wiley 10.1111/ijcp.12469
Lindner, Gregor; Funk, Georg-Christian; Pfortmüller, Carmen; Leichtle, Alexander B.; Fiedler, Georg M.; Schwarz, Christoph; Exadaktylos, Aristomenis K.; Puig, Stefan (2014). D-dimer to Rule Out Pulmonary Embolism in Renal Insufficiency. American journal of medicine, 127(4), pp. 343-347. Elsevier 10.1016/j.amjmed.2013.12.003
Dysli, Chantal-Simone; Quellec, Gwénolé; Abegg, Mathias; Menke, Marcel N; Wolf-Schnurrbusch, Ute; Kowal, Horst Jens; Blatz, Johannes; La Schiazza, Olivier; Leichtle, Alexander Benedikt; Wolf, Sebastian; Zinkernagel, Martin S (2014). Quantitative analysis of fluorescence lifetime measurements of the macula using the fluorescence lifetime imaging ophthalmoscope in healthy subjects. Investigative ophthalmology & visual science, 55(4), pp. 2106-2113. Association for Research in Vision and Ophthalmology 10.1167/iovs.13-13627
Pfortmüller, Carmen; Wiemann, Christoph; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Lindner, Gregor (2014). Hypoglycemia is associated with increased mortality in patients with acute decompensated liver cirrhosis. Journal of critical care, 29(2), 316.e7-316.e12. Elsevier 10.1016/j.jcrc.2013.11.002
Pfortmüller, Carmen; Lindner, Gregor; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2014). Diagnostic significance of high sensitivity troponin in diagnosis of blunt cardiac injury. Intensive care medicine, 40(4), pp. 623-624. Springer 10.1007/s00134-013-3204-5
Pfortmüller, Carmen A.; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christoph; Exadaktylos, Aristomenis; Lindner, Gregor (2014). Electrolyte disorders and in-hospital mortality during prolonged heat periods: a cross-sectional analysis. PLoS ONE, 9(3), e92150. Public Library of Science 10.1371/journal.pone.0092150
Lindner, Gregor; Pfortmüller, Carmen; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2014). Age-related variety in electrolyte levels and prevalence of dysnatremias and dyskalemias in patients presenting to the emergency department. Gerontology, 60(5), pp. 420-423. Karger 10.1159/000360134
Mai, Manuel; Tönjes, Anke; Kovacs, Peter; Stumvoll, Michael; Fiedler, Georg Martin; Leichtle, Alexander Benedikt (2013). Serum Levels of Acylcarnitines Are Altered in Prediabetic Conditions. PLoS ONE, 8(12), e82459. Public Library of Science 10.1371/journal.pone.0082459
Pfortmueller, Carmen A.; Funk, Georg-Christian; Marti, Grischa; Leichtle, Alexander B.; Fiedler, Georg M.; Schwarz, Christoph; Exadaktylos, Aristomenis K.; Lindner, Gregor (2013). Diagnostic performance of high-sensitive troponin T in patients with renal insufficiency. American journal of cardiology, 112(12), pp. 1968-1972. Elsevier 10.1016/j.amjcard.2013.08.028
Lindner, Gregor; Felber, Rainer; Schwarz, Christoph; Marti, Grischa; Leichtle, Alexander Benedikt; Fiedler, Martin; Zimmermann, Heinz; Arampatzis, Spyridon; Exadaktylos, Aristomenis Konstantinos (2013). Hypercalcemia in the ED: prevalence, etiology, and outcome. American journal of emergency medicine, 31(4), pp. 657-60. Philadelphia, Pa.: W.B. Saunders 10.1016/j.ajem.2012.11.010
Euteneuer, Sara; Yang, Kuo H; Chavez, Eduardo; Leichtle, Anke; Loers, Gabriele; Olshansky, Adel; Pak, Kwang; Schachner, Melitta; Ryan, Allen F (2013). Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM). Molecular and cellular neuroscience, 54, pp. 30-43. San Diego, Calif.: Elsevier 10.1016/j.mcn.2012.12.004
Leichtle, Alexander Benedikt; Ceglarek, U; Weinert, P; Nakas, C T; Nuoffer, Jean-Marc; Kase, J; Conrad, T; Witzigmann, H; Thiery, J; Fiedler, Martin (2013). Pancreatic carcinoma, pancreatitis, and healthy controls: metabolite models in a three-class diagnostic dilemma. Metabolomics, 9(3), pp. 677-687. New York, N.Y.: Springer 10.1007/s11306-012-0476-7
Marti, Grischa; Schwarz, Christoph; Leichtle, Alexander Benedikt; Fiedler, Martin; Arampatzis, Spyridon; Exadaktylos, Aristomenis; Lindner, Gregor (2013). Etiology and symptoms of severe hypokalemia in emergency department patients. European journal of emergency medicine, 21(1), pp. 46-51. London: Lippincott Williams & Wilkins
Arampatzis, Spyridon; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christoph; Zimmermann, Heinz; Exadaktylos, Aristomenis; Lindner, Gregor (2013). Impact of diuretic therapy-associated electrolyte disorders present on admission to the emergency department: a cross-sectional analysis. BMC medicine, 11, p. 83. London: BioMed Central 10.1186/1741-7015-11-83
Lindner, Gregor; Pfortmüller, Carmen; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2013). High-Sensitive Troponin Measurement in Emergency Department Patients Presenting with Syncope: A Retrospective Analysis. PLoS ONE, 8(6), e66470. Public Library of Science 10.1371/journal.pone.0066470
Leichtle, Alexander Benedikt; Dufour, Jean-François; Fiedler, Martin (2013). Potentials and pitfalls of clinical peptidomics and metabolomics. Swiss medical weekly, 143, w13801. EMH Schweizerischer Ärzteverlag 10.4414/smw.2013.13801
Leichtle, Alexander Benedikt; Nuoffer, Jean-Marc; Ceglarek, Uta; Kase, Julia; Conrad, Tim; Witzigmann, Helmut; Thiery, Joachim; Fiedler, Georg Martin (2012). Serum amino acid profiles and their alterations in colorectal cancer. Metabolomics, 8(4), pp. 643-653. New York, N.Y.: Springer 10.1007/s11306-011-0357-5
Schwarz, Christoph; Leichtle, Alexander Benedikt; Arampatzis, Spiros; Fiedler, Georg Martin; Zimmermann, Heinz; Exadaktylos, Aristomenis Konstantinos; Lindner, Gregor (2012). Thyroid function and serum electrolytes: does an association really exist? Swiss medical weekly, 142, w13669. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2012.13669
Arampatzis, Spyridon; Frauchiger, Bettina; Fiedler, Georg-Martin; Leichtle, Alexander Benedikt; Buhl, Daniela; Schwarz, Christoph; Funk, Georg-Christian; Zimmermann, Heinz; Exadaktylos, Aristomenis K; Lindner, Gregor (2012). Characteristics, symptoms, and outcome of severe dysnatremias present on hospital admission. American journal of medicine, 125(11), 1125.e1-1125.e7. Orlando, Fla.: Elsevier 10.1016/j.amjmed.2012.04.041
Leichtle, Alexander B; Helmschrodt, Christin; Ceglarek, Uta; Shai, Iris; Henkin, Yaakov; Schwarzfuchs, Dan; Golan, Rachel; Gepner, Yftach; Stampfer, Meir J; Blüher, Matthias; Stumvoll, Michael; Thiery, Joachim; Fiedler, Georg M (2011). Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men. American journal of clinical nutrition, 94(5), pp. 1189-95. Bethesda, Md.: American Society for Nutrition, Inc. 10.3945/ajcn.111.018119
Schumann, Julia; Leichtle, Alexander; Thiery, Joachim; Fuhrmann, Herbert (2011). Fatty acid and peptide profiles in plasma membrane and membrane rafts of PUFA supplemented RAW264.7 macrophages. PLoS ONE, 6(8), e24066. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0024066
Brauer, Romy; Leichtle, Alexander Benedikt; Fiedler, Georg Martin; Thiery, Joachim; Ceglarek, Uta (2011). Preanalytical standardization of amino acid and acylcarnitine metabolite profiling in human blood using tandem mass spectrometry. Metabolomics, 7(3), pp. 344-352. New York, N.Y.: Springer 10.1007/s11306-010-0256-1
