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Dohner, Eliane; Kierdorf, Fiona Joséphine; Langer, Rupert; Zuber, Markus; Fahrner, René (2024). Retrospective analysis of the incidence of appendiceal neoplasm and malignancy in patients treated for suspected acute appendicitis. BMC surgery, 24(121) BioMed Central 10.1186/s12893-024-02412-4
Liu, Drolaiz H W; Grabsch, Heike I; Gloor, Beat; Langer, Rupert; Dislich, Bastian (2023). Programmed death-ligand 1 (PD-L1) expression in primary gastric adenocarcinoma and matched metastases. Journal of cancer research and clinical oncology, 149(14), pp. 13345-13352. Springer 10.1007/s00432-023-05142-x
Saldanha, Oliver Lester; Muti, Hannah Sophie; Grabsch, Heike I; Langer, Rupert; Dislich, Bastian; Kohlruss, Meike; Keller, Gisela; van Treeck, Marko; Hewitt, Katherine Jane; Kolbinger, Fiona R; Veldhuizen, Gregory Patrick; Boor, Peter; Foersch, Sebastian; Truhn, Daniel; Kather, Jakob Nikolas (2023). Direct prediction of genetic aberrations from pathology images in gastric cancer with swarm learning. Gastric cancer, 26(2), pp. 264-274. Springer 10.1007/s10120-022-01347-0
Dislich, Bastian; Kröll, Dino; Langer, Rupert (2023). Surgical pathology of adenocarcinomas arising around or within the gastroesophageal junction. Updates in surgery, 75(2), pp. 395-402. Springer 10.1007/s13304-022-01360-z
Hofmann, Tobias; Matthias, Biebl; Knitter, Sebastian; Fehrenbach, Uli; Chopra, Sascha; Cetinkaya-Hosgor, Candan; Raakow, Jonas; Seika, Philippa; Langer, Rupert; Pratschke, Johann; Christian, Denecke; Kröll, Dino (2022). A 25 mm Circular Stapler Anastomosis Is Associated with Higher Anastomotic Leakage Rates Following Minimally Invasive Ivor Lewis Operation. Journal of clinical medicine, 11(23) MDPI 10.3390/jcm11237177
Carrara, Marta; Antenucci, Pietro; Liu, Shengchen; Kohler, Andreas; Langer, Rupert; Jakob, Stephan M; Ferrario, Manuela (2022). Autonomic and circulatory alterations persist despite adequate resuscitation in a 5-day sepsis swine experiment. Scientific Reports, 12(1), p. 19279. Nature Publishing Group 10.1038/s41598-022-23516-y
Ghaffari Laleh, Narmin; Muti, Hannah Sophie; Loeffler, Chiara Maria Lavinia; Echle, Amelie; Saldanha, Oliver Lester; Mahmood, Faisal; Lu, Ming Y; Trautwein, Christian; Langer, Rupert; Dislich, Bastian; Buelow, Roman D; Grabsch, Heike Irmgard; Brenner, Hermann; Chang-Claude, Jenny; Alwers, Elizabeth; Brinker, Titus J; Khader, Firas; Truhn, Daniel; Gaisa, Nadine T; Boor, Peter; ... (2022). Erratum to 'Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology' Medical Image Analysis, Volume 79, July 2022, 102474. Medical image analysis, 82(102622), p. 102622. Elsevier 10.1016/j.media.2022.102622
Liu, Shengchen; Kohler, Andreas; Langer, Rupert; Jakob, Manuel O; Salm, Lilian; Blank, Annika; Beldi, Guido; Jakob, Stephan M (2022). Hepatic blood flow regulation but not oxygen extraction capability is impaired in prolonged experimental abdominal sepsis. American journal of physiology - gastrointestinal and liver physiology, 323(4), G348-G361. American Physiological Society 10.1152/ajpgi.00109.2022
Ghaffari Laleh, Narmin; Truhn, Daniel; Veldhuizen, Gregory Patrick; Han, Tianyu; van Treeck, Marko; Buelow, Roman D; Langer, Rupert; Dislich, Bastian; Boor, Peter; Schulz, Volkmar; Kather, Jakob Nikolas (2022). Adversarial attacks and adversarial robustness in computational pathology. Nature Communications, 13(1), p. 5711. Springer Nature 10.1038/s41467-022-33266-0
Ghaffari Laleh, Narmin; Muti, Hannah Sophie; Loeffler, Chiara Maria Lavinia; Echle, Amelie; Saldanha, Oliver Lester; Mahmood, Faisal; Lu, Ming Y; Trautwein, Christian; Langer, Rupert; Dislich, Bastian; Buelow, Roman D; Grabsch, Heike Irmgard; Brenner, Hermann; Chang-Claude, Jenny; Alwers, Elizabeth; Brinker, Titus J; Khader, Firas; Truhn, Daniel; Gaisa, Nadine T; Boor, Peter; ... (2022). Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology. Medical image analysis, 79, p. 102474. Elsevier 10.1016/j.media.2022.102474
Dislich, Bastian; Mertz, Kirsten D; Gloor, Beat; Langer, Rupert (2022). Interspatial Distribution of Tumor and Immune Cells in Correlation with PD-L1 in Molecular Subtypes of Gastric Cancers. Cancers, 14(7) MDPI AG 10.3390/cancers14071736
Buck, Achim; Prade, Verena M; Kunzke, Thomas; Feuchtinger, Annette; Kröll, Dino; Feith, Marcus; Dislich, Bastian; Balluff, Benjamin; Langer, Rupert; Walch, Axel (2022). Metabolic tumor constitution is superior to tumor regression grading for evaluating response to neoadjuvant therapy of esophageal adenocarcinoma patients. The journal of pathology, 256(2), pp. 202-213. Wiley 10.1002/path.5828
Zens, Philipp; Bello, Corina; Scherz, Amina; Koenigsdorf, Julia; Pöllinger, Alexander; Schmid, Ralph A.; Ochsenbein, Adrian; Neppl, Christina; Langer, Rupert; Berezowska, Sabina Anna (2021). A prognostic score for non-small cell lung cancer resected after neoadjuvant therapy in comparison with the tumor-node-metastases classification and major pathological response. Modern pathology, 34(7), pp. 1333-1344. Springer Nature 10.1038/s41379-021-00777-y
Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia; ... (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. Taylor & Francis 10.1080/15548627.2020.1797280
Moullet, Barbara; Kolev, Mirjam; Ebner, Lukas; Langer, Rupert; Gräni, Christoph; Obmann, Verena; Maurer, Martin; Semmo, Nasser; Christe, Andreas; Huber, Adrian Thomas (2021). Adult form of Langerhans cell histiocytosis with pulmonary and hepatic Involvement mimicking malignancy in a patient with chronic hepatitis C infection. Radiology case reports, 16(2), pp. 327-333. Elsevier 10.1016/j.radcr.2020.11.022
Berezowska, Sabina; Schmid, Andreas; Losmanová, Tereza; Trippel, Mafalda; Blank, Annika; Banz, Yara; Jakob, Stephan M.; Langer, Rupert (2021). Frequency and Significance of Pathologic Pulmonary Findings in Postmortem Examinations—A Single Center Experience before COVID-19. Diagnostics, 11(5) MDPI 10.3390/diagnostics11050894
Tokarchuk, Igor; Janser, Félice A.; Schläfli, Anna M.; Pinto, Marta Teixeira; Humbert, Magali; Niklaus, Nicolas J.; Berezowska, Sabina; Langer, Rupert; Tschan, Mario P. (2021). Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability. Biochemical and biophysical research communications, 569, pp. 47-53. Elsevier 10.1016/j.bbrc.2021.06.082
Losmanová, Tereza; Janser, Félice A; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M; Neppl, Christina; Schmid, Ralph A; Tschan, Mario P; Langer, Rupert; Berezowska, Sabina (2021). Corrigendum to "Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung". Oxidative medicine and cellular longevity, 2021, p. 9846486. Hindawi 10.1155/2021/9846486
Laffranchi, Zita; Milella, Marco; Lombardo, Paolo; Langer, Rupert; Lösch, Sandra (2020). Co-occurrence of malignant neoplasm and Hyperostosis Frontalis Interna in an Iron Age individual from Münsingen-Rain (Switzerland): A multi-diagnostic study. International journal of paleopathology, 32, pp. 1-8. Elsevier 10.1016/j.ijpp.2020.10.008
Bräutigam, Konstantin; Hohl, Anja; Hewer, Ekkehard; Langer, Rupert; Jakob, Stephan (2020). Myeloid Sarcoma Mimicking Endocarditis: An Autopsy Case. International journal of surgical pathology, 28(7), p. 774. Sage 10.1177/1066896919900011
Reim, Daniel; Novotny, Alexander; Friess, Helmut; Slotta-Huspenina, Julia; Weichert, Wilko; Ott, Katja; Dislich, Bastian; Lorenzen, Sylvie; Becker, Karen; Langer, Rupert (2020). Significance of tumour regression in lymph node metastases of gastric and gastro-oesophageal junction adenocarcinomas. The journal of pathology: clinical research, 6(4), pp. 263-272. Wiley 10.1002/cjp2.169
Kröll, Dino; Borbély, Yves Michael; Dislich, Bastian; Haltmeier, Tobias; Malinka, Thomas; Biebl, Matthias; Langer, Rupert; Candinas, Daniel; Seiler, Christian (2020). Favourable long-term survival of patients with esophageal cancer treated with extended transhiatal esophagectomy combined with en bloc lymphadenectomy: results from a retrospective observational cohort study. BMC surgery, 20(1), p. 197. BioMed Central 10.1186/s12893-020-00855-z
Liu, Shengchen; do Amaral Campos, Pedro Paulo Zanella; Casoni, Daniela; Berger, David; Kohler, Andreas; Bloch, Andreas; Bervini, David; Setzer, Florian; Cameron, David R.; Z'Graggen, Werner; Hana, Anisa; Langer, Rupert; Corrêa, Thiago D.; Beldi, Guido; Takala, Jukka; Jakob, Stephan M. (2020). Defense mechanisms to increasing back pressure for hepatic oxygen transport and venous return in porcine fecal peritonitis. American journal of physiology - gastrointestinal and liver physiology, 319(3), G289-G302. American Physiological Society 10.1152/ajpgi.00216.2020
Galván, José A.; Wiprächtiger, Julia; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Kröll, Dino; Seiler, Christian A.; Langer, Rupert (2020). Immunohistochemical analysis of the expression of cancer-associated fibroblast markers in esophageal cancer with and without neoadjuvant therapy. Virchows Archiv, 476(5), pp. 725-734. Springer 10.1007/s00428-019-02714-6
Westerhoff, Maria; Osecky, Marek; Langer, Rupert (2020). Varying practices in tumor regression grading of gastrointestinal carcinomas after neoadjuvant therapy: results of an international survey. Modern pathology, 33(4), pp. 676-689. Nature Publishing Group 10.1038/s41379-019-0393-7
Dislich, Bastian; Blaser, Nicola; Berger, Martin D; Gloor, Beat; Langer, Rupert (2020). Preservation of Epstein-Barr-Virus Status and Mismatch Repair Protein Status along the Metastatic Course of Gastric Cancer. Histopathology, 76(5), pp. 740-747. Wiley 10.1111/his.14059
Humbert, Magali; Morán, María; de la Cruz-Ojeda, Patricia; Muntané, Jordi; Wiedmer, Tabea; Apostolova, Nadezda; McKenna, Sharon L; Velasco, Guillermo; Balduini, Walter; Eckhart, Leopold; Janji, Bassam; Sampaio-Marques, Belém; Ludovico, Paula; Žerovnik, Eva; Langer, Rupert; Perren, Aurel; Engedal, Nikolai; Tschan, Mario (2020). Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot. Biology, 9(3), pp. 1-24. MDPI 10.3390/biology9030059
Losmanová, Tereza; Janser, Félice A.; Humbert, Magali; Tokarchuk, Igor; Schläfli, Anna M.; Neppl, Christina; Schmid, Ralph; Tschan, Mario P.; Langer, Rupert; Berezowska, Sabina (2020). Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung. Oxidative medicine and cellular longevity, 2020, p. 8506572. Hindawi 10.1155/2020/8506572
Osecky, Marek Michal; Kröll, Dino; Feith, Marcus; Reim, Daniel; Dislich, Bastian; Becker, Karen; Langer, Rupert (2020). Tumor Regression in Lymph Node Metastases of Esophageal Adenocarcinomas after Neoadjuvant Therapy. Gastrointestinal disorders, 2(4), pp. 397-407. MDPI 10.3390/gidisord2040036
Huber, Katharina; Kunzke, Thomas; Buck, Achim; Langer, Rupert; Luber, Birgit; Feuchtinger, Annette; Walch, Axel (2019). Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis. Laboratory investigation, 99(10), pp. 1535-1546. Nature Publishing Group 10.1038/s41374-019-0268-z
Adams, Olivia; Janser, Félice A.; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A.; Kröll, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P.; Langer, Rupert (2019). Correction: A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 14(10), e0224832. Public Library of Science 10.1371/journal.pone.0224832
Langer, Rupert; Tröhler, Alexandra; Schnüriger, Beat; Perren, Aurel; Blank, Annika; Banz Wälti, Yara; Trippel, Mafalda; Candinas, Daniel; Lugli, Alessandro (2019). Implementation of modern tools in autopsy practice-the way towards contemporary postmortal diagnostics. Virchows Archiv, 474(2), pp. 149-158. Springer 10.1007/s00428-018-2482-2
Balluff, Benjamin; Buck, Achim; Martin-Lorenzo, Marta; Dewez, Frédéric; Langer, Rupert; McDonnell, Liam A.; Walch, Axel; Heeren, Ron M.A. (2019). Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification. Proteomics. Clinical applications, 13(1), p. 1800137. Wiley 10.1002/prca.201800137
Janser, Ariane F.; Tschan, Mario P.; Langer, Rupert (2019). The role of autophagy in HER2-targeted therapy. Swiss medical weekly, 149(149), w20138. EMH Media 10.4414/smw.2019.20138
Janser, Félice A.; Ney, Patricia; Teixeira Pinto, Marta; Langer, Rupert; Tschan, Mario P. (2019). The Chick Chorioallantoic Membrane (CAM) Assay as a Three-dimensional Model to Study Autophagy in Cancer Cells. Bio-protocol, 9(13) bio-protocol 10.21769/BioProtoc.3290
Trippel, Mafalda; Slotta-Huspenina, Julia; Becker, Karen; Rau, Tilman; Paepke, Stefan; Maurer-Marti, Franziska; Langer, Rupert (2018). Macroscopic Evaluation of the Trimmed Frozen Block Is a Helpful Tool for Intraoperative Assessment of Resection Margins of Breast Cancer Specimens. International journal of surgical pathology, 26(8), pp. 693-700. Sage 10.1177/1066896918780346
Patil, Deepa T.; Hammer, Suntrea; Langer, Rupert; Yantiss, Rhonda K. (2018). Lymphocytic esophagitis: an update on histologic diagnosis, endoscopic findings, and natural history. Annals of the New York Academy of Sciences, 1434(1), pp. 185-191. Blackwell 10.1111/nyas.13710
El-Zimaity, Hala; Di Pilato, Vincenzo; Novella Ringressi, Maria; Brcic, Iva; Rajendra, Shanmugarajah; Langer, Rupert; Dislich, Bastian; Tripathi, Monika; Guindi, Maha; Riddell, Robert (2018). Risk factors for esophageal cancer: emphasis on infectious agents. Annals of the New York Academy of Sciences, 1434(1), pp. 319-332. Blackwell 10.1111/nyas.13858
Neppl, Christina; Kaderli, Reto M.; Trepp, Roman; Schmitt, Anja M.; Berger, Martin D.; Wehrli, Marc; Seiler, Christian A.; Langer, Rupert (2018). Histology of Nivolumab-Induced Thyroiditis. Thyroid, 28(12), pp. 1727-1728. Mary Ann Liebert 10.1089/thy.2018.0418
Jent, Philipp; Trippel, Mafalda; Frey, Manuel; Pöllinger, Alexander; Berezowska, Sabina; Langer, Rupert; Furrer, Hansjakob; Béguelin, Charles Antoine (2018). Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient. Open Forum Infectious Diseases, 5(11), ofy244. Oxford University Press 10.1093/ofid/ofy244
Janser, Félice A.; Adams, Olivia Joan; Bütler, Vanessa; Bill, Anna Magdalena; Dislich, Bastian; Seiler, Christian A.; Kröll, Dino; Langer, Rupert; Tschan, Mario (2018). Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells. International journal of molecular sciences, 19(10) MDPI 10.3390/ijms19103069
Graule, Janina; Uth-Gottardi, Kristin; Fischer, Elia Luca; Centeno Ramos, Irene; Galván Hernández, José Alberto; Eichmann, Micha David; Rau, Tilman; Langer, Rupert; Dawson, Heather; Nitsche, Ulrich; Traeger, Peter; Berger, Martin Dave; Schnüriger, Beat; Hädrich, Marion; Studer, Peter; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2018). CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. Clinical epigenetics, 10(1), p. 120. Springer 10.1186/s13148-018-0548-2
Langer, Rupert; Becker, Karen (2018). Tumor regression grading of gastrointestinal cancers after neoadjuvant therapy. Virchows Archiv, 472(2), pp. 175-186. Springer 10.1007/s00428-017-2232-x
Kröll, Dino; Noser, Laura; Erdem, Suna; Zlobec, Inti; Storni, Federico Lorenzo; Arnold, Dominik; Dislich, Bastian; Seiler, Christian A.; Candinas, Daniel; Langer, Rupert (2018). Application of the 8th edition of the AJCC yTNM staging system shows improved prognostication in a single center cohort of esophageal carcinomas. Surgical oncology, 27(1), pp. 100-105. Elsevier 10.1016/j.suronc.2017.12.005
Keller, Manuel D; Neppl, Christina; Irmak, Yasin; Hall, Sean; Schmid, Ralph; Langer, Rupert; Berezowska, Sabina Anna (2018). Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. Modern pathology, 31(1), pp. 101-110. Nature Publishing Group 10.1038/modpathol.2017.111
Adams, Olivia; Janser, Félice A.; Dislich, Bastian; Berezowska, Sabina; Humbert, Magali; Seiler, Christian A.; Kroell, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario P.; Langer, Rupert (2018). A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 13(6), e0197610. Public Library of Science 10.1371/journal.pone.0197610
Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281
Shukla, Sachet A.; Bachireddy, Pavan; Schilling, Bastian; Galonska, Christina; Zhan, Qian; Bango, Clyde; Langer, Rupert; Lee, Patrick C.; Gusenleitner, Daniel; Keskin, Derin B.; Babadi, Mehrtash; Mohammad, Arman; Gnirke, Andreas; Clement, Kendell; Cartun, Zachary J.; Van Allen, Eliezer M.; Miao, Diana; Huang, Ying; Snyder, Alexandra; Merghoub, Taha; ... (2018). Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell, 173(3), 624-633.e8. Cell Press 10.1016/j.cell.2018.03.026
Slotta-Huspenina, Julia; Drecoll, Enken; Feith, Marcus; Habermehl, Daniel; Combs, Stephanie; Weichert, Wilko; Bettstetter, Marcus; Becker, Karen; Langer, Rupert (2018). MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus. Journal of translational medicine, 16(1), p. 109. BioMed Central 10.1186/s12967-018-1492-9
Boxberg, Melanie; Steiger, Katja; Lenze, Ulrich; Rechl, Hans; von Eisenhart-Rothe, Rüdiger; Wörtler, Klaus; Weichert, Wilko; Langer, Rupert; Specht, Katja (2018). PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue – prognostic implications and rationale for immunotherapy. Oncoimmunology, 7(3), e1389366. Taylor & Francis 10.1080/2162402x.2017.1389366
Sartori, Elsa; Langer, Rupert; Vassella, Erik; Hewer, Ekkehard; Schucht, Philippe; Zlobec, Inti; Berezowska, Sabina Anna (2017). Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type. Oncology reports, 38(4), pp. 2394-2400. Spandidos Publications 10.3892/or.2017.5863
Alderson, Derek; Cunningham, David; Nankivell, Matthew; Blazeby, Jane M; Griffin, S Michael; Crellin, Adrian; Grabsch, Heike I; Langer, Rupert; Pritchard, Susan; Okines, Alicia; Krysztopik, Richard; Coxon, Fareeda; Thompson, Joyce; Falk, Stephen; Robb, Clare; Stenning, Sally; Langley, Ruth E (2017). Neoadjuvant cisplatin and fluorouracil versus epirubicin, cisplatin, and capecitabine followed by resection in patients with oesophageal adenocarcinoma (UK MRC OE05): an open-label, randomised phase 3 trial. The lancet oncology, 18(9), pp. 1249-1260. Elsevier 10.1016/S1470-2045(17)30447-3
Niklaus, Monique; Adams, Olivia Joan; Berezowska, Sabina Anna; Zlobec, Inti; Graber, Franziska; Slotta-Huspenina, Julia; Nitsche, Ulrich; Rosenberg, Robert; Tschan, Mario; Langer, Rupert (2017). Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer. OncoTarget, 8(33), pp. 54604-54615. Impact Journals LLC 10.18632/oncotarget.17554
Jesinghaus, Moritz; Steiger, Katja; Slotta-Huspenina, Julia; Drecoll, Enken; Pfarr, Nicole; Meyer, Petra; Konukiewitz, Björn; Bettstetter, Marcus; Wieczorek, Kathrin; Ott, Katja; Feith, Markus; Langer, Rupert; Weichert, Wilko; Specht, Katja; Boxberg, Melanie (2017). Increased intraepithelial CD3+ T-lymphocytes and high PD-L1 expression on tumor cells are associated with a favorable prognosis in esophageal squamous cell carcinoma and allow prognostic immunogenic subgrouping. OncoTarget, 8(29), pp. 46756-46768. Impact Journals LLC 10.18632/oncotarget.18606
Dislich, Bastian; Stein, Alexandra Vanessa; Seiler, Christian A.; Kröll, Dino; Berezowska, Sabina Anna; Zlobec, Inti; Galván Hernández, José Alberto; Slotta-Huspenina, Julia; Walch, Axel; Langer, Rupert (2017). Expression patterns of programmed death-ligand 1 in esophageal adenocarcinomas: comparison between primary tumors and metastases. Cancer immunology, immunotherapy, 66(6), pp. 777-786. Springer 10.1007/s00262-017-1982-2
Berezowska, Sabina Anna; Galván Hernández, José Alberto; Langer, Rupert; Bubendorf, Lukas; Savic, Spasenija; Gugger, Mathias; Schmid, Ralph; Marti, Thomas (2017). Glycine decarboxylase and HIF-1α expression are negative prognostic factors in primary resected early-stage non-small cell lung cancer. Virchows Archiv, 470(3), pp. 323-330. Springer 10.1007/s00428-016-2057-z
Stein, Alexandra Vanessa; Dislich, Bastian; Blank, Annika; Guldener, Lars; Kröll, Dino; Seiler, Christian A.; Langer, Rupert (2017). High intratumoural but not peritumoural inflammatory host response is associated with better prognosis in primary resected oesophageal adenocarcinomas. Pathology, 49(1), pp. 30-37. Elsevier 10.1016/j.pathol.2016.10.005
Dislich, Bastian; Stein, Alexandra Vanessa; Galván Hernández, José Alberto; Berezowska, Sabina Anna; Seiler, Christian A.; Kröll, Dino; Langer, Rupert (2017). P2.04-026 Expression Patterns of PD-L1 in Esophageal Adenocarcinomas: Comparison between Primary Tumors and Metastases. Journal of thoracic oncology, 12(1S), s1012-s1012. Elsevier 10.1016/j.jtho.2016.11.1406
Kunzke, Thomas; Balluff, Benjamin; Feuchtinger, Annette; Buck, Achim; Langer, Rupert; Luber, Birgit; Lordick, Florian; Zitzelsberger, Horst; Aichler, Michaela; Walch, Axel (2017). Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome. OncoTarget, 8(40), pp. 68012-68025. Impact Journals LLC 10.18632/oncotarget.19137
Kollár, Attila; Langer, Rupert; Ionescu, Codruta; Cullmann, Jennifer L.; Klenke, Frank M (2016). Pleomorphic rhabdomyosarcoma with an impressive response to chemotherapy: case report and review of the literature. Tumori, 102(Suppl.2), S57-S60. Wichtig Publishing 10.5301/tj.5000476
Francica, Paola; Nisa Hernandez, Lluis; Aebersold, Daniel; Langer, Rupert; Bladt, Friedhelm; Blaukat, Andree; Keogh-Stroka, Deborah M.; Martínez, María Rodríguez; Zimmer, Yitzhak; Medova, Michaela (2016). Depletion of FOXM1 via MET Targeting Underlies Establishment of a DNA Damage-Induced Senescence Program in Gastric Cancer. Clinical cancer research, 22(21), pp. 5322-5336. American Association for Cancer Research 10.1158/1078-0432.CCR-15-2987
Dawson, Heather; Novotny, Alexander; Becker, Karen; Reim, Daniel; Langer, Rupert; Gullo, Irene; Svrcek, Magali; Niess, Jan Hendrik; Tutuian, Radu; Truninger, Kaspar; Diamantis, Ioannis; Blank, Annika; Zlobec, Inti; Riddell, Robert H; Carneiro, Fatima; Fléjou, Jean-François; Genta, Robert M; Lugli, Alessandro (2016). Macroscopy predicts tumor progression in gastric cancer: A retrospective patho-historical analysis based on Napoleon Bonaparte's autopsy report. Digestive and liver disease, 48(11), pp. 1378-1385. Elsevier 10.1016/j.dld.2016.07.013
Langer, Rupert; Streutker, Catherine J; Swanson, Paul E (2016). Autophagy and its current relevance to the diagnosis and clinical management of esophageal diseases. Annals of the New York Academy of Sciences, 1381(1), pp. 113-121. Wiley 10.1111/nyas.13190
Ly, Alice; Buck, Achim; Balluff, Benjamin; Sun, Na; Gorzolka, Karin; Feuchtinger, Annette; Janssen, Klaus-Peter; Kuppen, Peter J K; van de Velde, Cornelis J H; Weirich, Gregor; Erlmeier, Franziska; Langer, Rupert; Aubele, Michaela; Zitzelsberger, Horst; McDonnell, Liam; Aichler, Michaela; Walch, Axel (2016). High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue. Nature protocols, 11(8), pp. 1428-1443. Nature Publishing Group 10.1038/nprot.2016.081
Adams, Olivia Joan; Dislich, Bastian; Berezowska, Sabina Anna; Schläfli, Anna; Seiler, Christian A.; Kröll, Dino; Tschan, Mario; Langer, Rupert (2016). Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas. OncoTarget, 7(26), pp. 39241-39255. Impact Journals LLC 10.18632/oncotarget.9649
Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647
Thies, Svenja; Guldener, Lars; Slotta-Huspenina, Julia; Zlobec, Inti; Kölzer, Viktor; Lugli, Alessandro; Kröll, Dino; Seiler, Christian A.; Feith, Marcus; Langer, Rupert (2016). Impact of peritumoral and intratumoral budding in esophageal adenocarcinomas. Human pathology, 52, pp. 1-8. Elsevier 10.1016/j.humpath.2016.01.016
Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3
Straub, Melanie; Drecoll, Enken; Pfarr, Nicole; Weichert, Wilko; Langer, Rupert; Hapfelmeier, Alexander; Götz, Carolin; Wolff, Klaus-Dietrich; Kolk, Andreas; Specht, Katja (2016). CD274/PD-L1 gene amplification and PD-L1 protein expression are common events in squamous cell carcinoma of the oral cavity. OncoTarget, 7(11), pp. 12024-12034. Impact Journals LLC 10.18632/oncotarget.7593
Sachpekidis, Christos; Langer, Rupert; Kollár, Attila; Wartenberg, Jan (2016). Detection of a primary tumor in the area of the renal artery with 18F-FDG PET/CT in a patient with metastatic undifferentiated sarcoma and a history of mid-aortic syndrome: A case report. Medicine, 95(34), e4622. Lippincott Williams & Wilkins 10.1097/MD.0000000000004622
Schafroth, Christian; Galván Hernández, José Alberto; Centeno Ramos, Irene; Kölzer, Viktor; Dawson, Heather; Sokol, Lena; Rieger, Gregor; Berger, Martin D; Hädrich, Marion; Rosenberg, Robert; Nitsche, Ulrich; Schnüriger, Beat; Langer, Rupert; Inderbitzin, Daniel; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti (2015). VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer. OncoTarget, 6(39), pp. 41453-41463. Impact Journals LLC 10.18632/oncotarget.6162
Springfeld, Christoph; Wiecha, Christiane; Kunzmann, Romy; Heger, Ulrike; Weichert, Wilko; Langer, Rupert; Stange, Annika; Blank, Susanne; Sisic, Leila; Schmidt, Thomas; Lordick, Florian; Jäger, Dirk; Grenacher, Lars; Bruckner, Tom; Büchler, Markus W; Ott, Katja (2015). Influence of Different Neoadjuvant Chemotherapy Regimens on Response, Prognosis, and Complication Rate in Patients with Esophagogastric Adenocarcinoma. Annals of surgical oncology, 22(Suppl 3), pp. 905-914. Springer 10.1245/s10434-015-4617-x
Noujaim, Jonathan; Thway, Khin; Jones, Robin L; Miah, Aisha; Khabra, Komel; Langer, Rupert; Kasper, Bernd; Judson, Ian; Benson, Charlotte; Kollár, Attila (2015). Adult Pleomorphic Rhabdomyosarcoma: A Multicentre Retrospective Study. Anticancer research, 35(11), pp. 6213-6217. International Inst. of Anticancer Research
Buck, Achim; Ly, Alice; Balluff, Benjamin; Sun, Na; Gorzolka, Karin; Feuchtinger, Annette; Janssen, Klaus-Peter; Kuppen, Peter J K; van de Velde, Cornelis J H; Weirich, Gregor; Erlmeier, Franziska; Langer, Rupert; Aubele, Michaela; Zitzelsberger, Horst; Aichler, Michaela; Walch, Axel (2015). High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed, paraffin-embedded clinical tissue samples. Journal of pathology, 237(1), pp. 123-132. Wiley 10.1002/path.4560
Hirzel, Cédric; Nueesch, Susanne; Wendland, Thomas; Langer, Rupert (2015). Necrotizing herpes-simplex virus tonsillitis mimicking peritonsillar abscess. Infection, 44(2), pp. 267-268. Springer-Medizin-Verlag 10.1007/s15010-015-0823-5
Karamitopoulou, Evanthia; Zlobec, Inti; Kölzer, Viktor; Langer, Rupert; Dawson, Heather; Lugli, Alessandro (2015). Tumour border configuration in colorectal cancer: proposal for an alternative scoring system based on the percentage of infiltrating margin. Histopathology, 67(4), pp. 464-473. Blackwell Scientific Publications 10.1111/his.12665
Feuchtinger, Annette; Stiehler, Tabitha; Jütting, Uta; Marjanovic, Goran; Luber, Birgit; Langer, Rupert; Walch, Axel (2015). Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma. Histochemistry and cell biology, 143(1), pp. 1-9. Springer 10.1007/s00418-014-1258-2
Blank, Susanne; Lordick, Florian; Bader, Franz; Burian, Maria; Dobritz, Martin; Grenacher, Lars; Becker, Karen; Weichert, Wilko; Langer, Rupert; Sisic, Leila; Stange, Annika; Jäger, Dirk; Büchler, Markus; Bruckner, Thomas; Siewert, Jörg; Ott, Katja (2015). Post-therapeutic response evaluation by a combination of endoscopy and CT scan in esophagogastric adenocarcinoma after chemotherapy: better than its reputation. Gastric cancer, 18(2), pp. 314-325. Springer 10.1007/s10120-014-0367-x
Genitsch Gratwohl, Vera; Novotny, Alexander; Seiler, Christian A.; Kröll, Dino; Walch, Axel; Langer, Rupert (2015). Epstein-barr virus in gastro-esophageal adenocarcinomas - single center experiences in the context of current literature. Frontiers in oncology, 5(73), p. 73. Frontiers Research Foundation 10.3389/fonc.2015.00073
Schläfli, Anna; Berezowska, Sabina Anna; Adams, Olivia Joan; Langer, Rupert; Tschan, Mario (2015). Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry. European journal of histochemistry, 59(2), p. 2481. Luigi Ponzio 10.4081/ejh.2015.2481
Bauer, Lukas; Takacs, Agnes; Slotta-Huspenina, Julia; Langer, Rupert; Becker, Karen; Novotny, Alexander; Ott, Katja; Walch, Axel; Hapfelmeier, Alexander; Keller, Gisela (2015). Clinical Significance of NOTCH1 and NOTCH2 Expression in Gastric Carcinomas: An Immunohistochemical Study. Frontiers in oncology, 5(94), p. 94. Frontiers Research Foundation 10.3389/fonc.2015.00094
Gündisch, Sibylle; Slotta-Huspenina, Julia; Verderio, Paolo; Ciniselli, Chiara Maura; Pizzamiglio, Sara; Schott, Christina; Drecoll, Enken; Viertler, Christian; Zatloukal, Kurt; Kap, Marcel; Riegman, Peter; Esposito, Irene; Specht, Katja; Babaryka, Gregor; Asslaber, Martin; Bodó, Koppany; den Bakker, Michael; den Hollander, Jan; Fend, Falko; Neumann, Jens; ... (2014). Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial. Virchows Archiv, 465(5), pp. 509-519. Springer 10.1007/s00428-014-1624-4
Karamitopoulou, Evanthia; Thies, Svenja; Zlobec, Inti; Ott, Katja; Feith, Marcus; Slotta-Huspenina, Julia; Lordick, Florian; Becker, Karen; Langer, Rupert (2014). Assessment of tumor regression of esophageal adenocarcinomas after neoadjuvant chemotherapy: comparison of 2 commonly used scoring approaches. The American journal of surgical pathology, 38(11), pp. 1551-1556. Lippincott Williams & Wilkins 10.1097/PAS.0000000000000255
Liebl, Florian; Demir, Ihsan Ekin; Mayer, Katharina; Schuster, Tibor; DʼHaese, Jan G; Becker, Karen; Langer, Rupert; Bergmann, Frank; Wang, Kun; Rosenberg, Robert; Novotny, Alexander R; Feith, Marcus; Reim, Daniel; Friess, Helmut; Ceyhan, Güralp O (2014). The impact of neural invasion severity in gastrointestinal malignancies: a clinicopathological study. Annals of surgery, 260(5), pp. 900-907. Lippincott Williams & Wilkins 10.1097/SLA.0000000000000968
Kaemmerer, D; Posorski, N; von Eggeling, F; Ernst, G; Hörsch, D; Baum, R P; Prasad, V; Langer, Rupert; Esposito, I; Klöppel, G; Sehner, S; Knösel, T; Hommann, M (2014). The search for the primary tumor in metastasized gastroenteropancreatic neuroendocrine neoplasm. Clinical & experimental metastasis, 31(7), pp. 817-827. Springer 10.1007/s10585-014-9672-3
Allum, William H; Bonavina, Luigi; Cassivi, Stephen D; Cuesta, Miguel A; Dong, Zhao Ming; Felix, Valter Nilton; Figueredo, Edgar; Gatenby, Piers A C; Haverkamp, Leonie; Ibraev, Maksat A; Krasna, Mark J; Lambert, René; Langer, Rupert; Lewis, Michael P N; Nason, Katie S; Parry, Kevin; Preston, Shaun R; Ruurda, Jelle P; Schaheen, Lara W; Tatum, Roger P; ... (2014). Surgical treatments for esophageal cancers. Annals of the New York Academy of Sciences, 1325, pp. 242-268. Blackwell 10.1111/nyas.12533
Al-Haddad, Sahar; Chang, Andrew C; De Hertogh, Gert; Grin, Andrea; Langer, Rupert; Sagaert, Xavier; Salemme, Marianna; Streutker, Catherine J; Soucy, Geneviève; Tripathi, Monika; Upton, Melissa P; Vieth, Michael; Villanacci, Vincenzo (2014). Adenocarcinoma at the gastroesophageal junction. Annals of the New York Academy of Sciences, 1325, pp. 211-225. Blackwell 10.1111/nyas.12535
Cotton, Richard G H; Langer, Rupert; Leong, Trevor; Martinek, Jan; Sewram, Vikash; Smithers, Mark; Swanson, Paul E; Qiao, You-Lin; Udagawa, Harushi; Ueno, Masaki; Wang, Meng; Wei, Wen-Qiang; White, Russell E (2014). Coping with esophageal cancer approaches worldwide. Annals of the New York Academy of Sciences, 1325, pp. 138-158. Blackwell 10.1111/nyas.12522
Aichler, Michaela; Motschmann, Martin; Jütting, Uta; Luber, Birgit; Becker, Karen; Ott, Katja; Lordick, Florian; Langer, Rupert; Feith, Marcus; Siewert, Jörg Rüdiger; Walch, Axel (2014). Epidermal growth factor receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy. OncoTarget, 5(16), pp. 6620-6632. Impact Journals LLC
Helbling, Melina; Lukesch, Anne Carolin; Haimovici, Aladin; Karamitopoulou, Evanthia; Berger, Martin Dave; Hädrich, Marion; Mallaev, Makhmud; Schnüriger, Beat; Kölzer, Viktor; Dawson, Heather; Borner, Markus; Langer, Rupert; Rosenberg, Robert; Nitsche, Ulrich; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2014). Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients. OncoTarget, 5(13), pp. 4671-4682. Impact Journals LLC
Geppert, C-I; Rümmele, P; Sarbia, M; Langer, Rupert; Feith, M; Morrison, L; Pestova, E; Schneider-Stock, R; Hartmann, A; Rau, Tilman (2014). Multi-colour FISH in oesophageal adenocarcinoma-predictors of prognosis independent of stage and grade. British journal of cancer, 110(12), pp. 2985-2995. Nature Publishing Group 10.1038/bjc.2014.238
Drecoll, Enken; Nitsche, Ulrich; Bauer, Karina; Berezowska, Sabina Anna; Slotta-Huspenina, Julia; Rosenberg, Robert; Langer, Rupert (2014). Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma. International journal of colorectal disease, 29(6), pp. 663-671. Springer 10.1007/s00384-014-1857-3
Heger, Ulrike; Blank, Susanne; Wiecha, Christiane; Langer, Rupert; Weichert, Wilko; Lordick, Florian; Bruckner, Thomas; Dobritz, Martin; Burian, Maria; Springfeld, Christoph; Grenacher, Lars; Siewert, Jörg-Rüdiger; Büchler, Markus; Ott, Katja (2014). Is preoperative chemotherapy followed by surgery the appropriate treatment for signet ring cell containing adenocarcinomas of the esophagogastric junction and stomach? Annals of surgical oncology, 21(5), pp. 1739-1748. Springer 10.1245/s10434-013-3462-z
Langer, Rupert; Becker, Karen; Zlobec, Inti; Gertler, Ralf; Sisic, Leila; Büchler, Markus; Lordick, Florian; Slotta-Huspenina, Julia; Weichert, Wilko; Höfler, Heinz; Feith, Marcus; Ott, Katja (2014). A multifactorial histopathologic score for the prediction of prognosis of resected esophageal adenocarcinomas after neoadjuvant chemotherapy. Annals of surgical oncology, 21(3), pp. 915-921. Springer 10.1245/s10434-013-3410-y
Schmidt, T; Sicic, L; Blank, S; Becker, K; Weichert, W; Bruckner, T; Parakonthun, T; Langer, Rupert; Büchler, M W; Siewert, J-R; Lordick, F; Ott, K (2014). Prognostic value of histopathological regression in 850 neoadjuvantly treated oesophagogastric adenocarcinomas. British journal of cancer, 110(7), pp. 1712-1720. Nature Publishing Group 10.1038/bjc.2014.94
Holzscheiter, Maria; Layland, Laura E.; Loffredo-Verde, Eva; Mair, Katrin; Vogelmann, Roger; Langer, Rupert; Wagner, Hermann; Prazeres da Costa, Clarissa (2014). Lack of Host Gut Microbiota Alters Immune Responses and Intestinal Granuloma Formation during Schistosomiasis. Clinical and experimental immunology, 175(2), pp. 246-257. Blackwell Scientific Publications 10.1111/cei.12230
Langer, Rupert; Reim, Daniel; Höfler, Heinz; Becker, Karen (2014). Reply to letter: "Tumor regression after neoadjuvant chemotherapy in gastric carcinoma: are there really so few responders?". Annals of surgery, 259(2), e30. Lippincott Williams & Wilkins 10.1097/SLA.0000000000000280
Heger, Ulrike; Bader, Franz; Lordick, Florian; Burian, Maria; Langer, Rupert; Dobritz, Martin; Blank, Susanne; Bruckner, Thomas; Becker, Karen; Herrmann, Ken; Siewert, Jörg-Rüdiger; Ott, Katja (2014). Interim endoscopy results during neoadjuvant therapy for gastric cancer correlate with histopathological response and prognosis. Gastric cancer, 17(3), pp. 478-488. Springer 10.1007/s10120-013-0296-0
Kölzer, Viktor; Langer, Rupert; Zlobec, Inti; Lugli, Alessandro (2014). Tumor budding in upper gastrointestinal carcinomas. Frontiers in oncology, 4(216), p. 216. Frontiers Research Foundation 10.3389/fonc.2014.00216
Slotta-Huspenina, Julia; Becker, Karl-Friedrich; Feith, Marcus; Walch, Axel; Langer, Rupert (2014). Heat Shock Protein 90 (HSP90) and Her2 in Adenocarcinomas of the Esophagus. Cancers, 6(3), pp. 1382-1393. MDPI AG 10.3390/cancers6031382
Blank, Susanne; Rachakonda, Sivaramakrishna; Keller, Gisela; Weichert, Wilko; Lordick, Florian; Langer, Rupert; Springfeld, Christoph; Bruckner, Thomas; Becker, Karen; Kumar, Rajiv; Ott, Katja (2014). A retrospective comparative exploratory study on two methylentetrahydrofolate reductase (MTHFR) polymorphisms in esophagogastric cancer: the A1298C MTHFR polymorphism is an independent prognostic factor only in neoadjuvantly treated gastric cancer patients. BMC cancer, 14(58), p. 58. BioMed Central 10.1186/1471-2407-14-58
Aichler, Michaela; Elsner, Mareike; Ludyga, Natalie; Feuchtinger, Annette; Zangen, Verena; Maier, Stefan K.; Balluff, Benjamin; Schöne, Cédrik; Hierber, Ludwig; Braselmann, Herbert; Meding, Stephan; Rauser, Sandra; Zischka, Hans; Aubele, Michaela; Schmitt, Manfred; Feith, Marcus; Hauck, Stefanie M; Ueffing, Marius; Langer, Rupert; Kuster, Bernhard; ... (2013). Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria. Journal of pathology, 230(4), pp. 410-419. Wiley 10.1002/path.4199
Moghaddam, Negahnaz; Langer, Rupert; Ross, Steffen; Nielsen, Ebbe; Lösch, Sandra (2013). Multiple osteosclerotic lesions in an Iron Age skull from Switzerland (320 - 250 BC) - An unusual case. Swiss medical weekly, 29(143), w13819. EMH Schweizerischer Ärzteverlag 10.4414/smw.2013.13819
Slotta-Huspenina, J.; Wolff, C.; Drecoll, E.; Feith, M.; Bettstetter, M.; Malinowsky, K.; Bauer, L.; Becker, K.; Ott, K.; Höfler, H.; Becker, K.-F.; Langer, Rupert (2013). A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas. British journal of cancer, 109(2), pp. 370-378. Nature Publishing Group 10.1038/bjc.2013.319
Schwitalla, Sarah; Ziegler, Paul K.; Horst, David; Becker, Valentin; Kerle, Irina; Begus-Nahrmann, Yvonne; Lechel, André; Rudolph, K. Lenhard; Langer, Rupert; Slotta-Huspenina, Julia; Bader, Franz G.; Prazeres da Costa, Olivia; Neurath, Markus F.; Meining, Alexander; Kirchner, Thomas; Greten, Florian R. (2013). Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors. Cancer cell, 23(1), pp. 93-106. Cell Press 10.1016/j.ccr.2012.11.014
Reim, Daniel; Loos, Martin; Vogl, Fabian; Novotny, Alexander; Schuster, Tibor; Langer, Rupert; Becker, Karen; Höfler, Heinz; Siveke, Jens; Bassermann, Florian; Friess, Helmut; Schuhmacher, Christoph (2013). Prognostic implications of the seventh edition of the international union against cancer classification for patients with gastric cancer: the Western experience of patients treated in a single-center European institution. Journal of clinical oncology, 31(2), pp. 263-271. American Society of Clinical Oncology 10.1200/JCO.2012.44.4315
Liebl, Florian; Demir, Ihsan Ekin; Rosenberg, Robert; Boldis, Alexandra; Yildiz, Esra; Kujundzic, Kristina; Kehl, Timo; Dischl, Dominic; Schuster, Tibor; Maak, Matthias; Becker, Karen; Langer, Rupert; Laschinger, Melanie; Friess, Helmut; Ceyhan, Güralp O. (2013). The severity of neural invasion is associated with shortened survival in colon cancer. Clinical cancer research, 19(1), pp. 50-61. American Association for Cancer Research 10.1158/1078-0432.CCR-12-2392
Bettstetter, Marcus; Berezowska, Sabina; Keller, Gisela; Walch, Axel; Feuchtinger, Annette; Slotta-Huspenina, Julia; Feith, Marcus; Drecoll, Enken; Höfler, Heinz; Langer, Rupert (2013). Epidermal growth factor receptor, phosphatidylinositol-3-kinase catalytic subunit/PTEN, and KRAS/NRAS/BRAF in primary resected esophageal adenocarcinomas: loss of PTEN is associated with worse clinical outcome. Human pathology, 44(5), pp. 829-36. Philadelphia, Pa.: Elsevier 10.1016/j.humpath.2012.08.005
Gollwitzer, Hans; Gloeck, Timo; Roessner, Michaela; Langer, Rupert; Horn, Carsten; Gerdesmeyer, Ludger; Diehl, Peter (2013). Radial extracorporeal shock wave therapy (rESWT) induces new bone formation in vivo: results of an animal study in rabbits. Ultrasound in medicine & biology, 39(1), pp. 126-33. Tarrytown, NY: Elsevier 10.1016/j.ultrasmedbio.2012.08.026
Thies, Svenja; Langer, Rupert (2013). Tumor Regression Grading of Gastrointestinal Carcinomas after Neoadjuvant Treatment. Frontiers in oncology, 3, p. 262. Frontiers Research Foundation 10.3389/fonc.2013.00262
Berezowska, Sabina Anna; Novotny, Alexander; Bauer, Karina; Feuchtinger, Annette; Slotta-Huspenina, Julia; Becker, Karen; Langer, Rupert; Walch, Axel (2013). Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas. PLoS ONE, 8(7), e69098. Public Library of Science 10.1371/journal.pone.0069098
Ott, Katja; Blank, Susanne; Becker, Karen; Langer, Rupert; Weichert, Wilko; Roth, Wilfried; Sisic, Leila; Stange, Annika; Jäger, Dirk; Büchler, Markus; Siewert, Jörg-Rüdiger; Lordick, Florian (2012). Factors predicting prognosis and recurrence in patients with esophago-gastric adenocarcinoma and histopathological response with less than 10 % residual tumor. Langenbeck's archives of surgery, 398(2), pp. 239-249. Berlin: Springer 10.1007/s00423-012-1039-0
Wulfkuhle, Julia D; Berg, Daniela; Wolff, Claudia; Langer, Rupert; Tran, Kai; Illi, Julie; Espina, Virginia; Pierobon, Mariaelena; Deng, Jianghong; DeMichele, Angela; Walch, Axel; Bronger, Holger; Becker, Ingrid; Waldhör, Christine; Höfler, Heinz; Esserman, Laura; Liotta, Lance A; Becker, Karl-Friedrich; Petricoin, Emanuel F (2012). Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping. Clinical cancer research, 18(23), pp. 6426-35. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-0452
Bauer, Lukas; Langer, Rupert; Becker, Karen; Hapfelmeier, Alexander; Ott, Katja; Novotny, Alexander; Höfler, Heinz; Keller, Gisela (2012). Expression profiling of stem cell-related genes in neoadjuvant-treated gastric cancer: a NOTCH2, GSK3B and β-catenin gene signature predicts survival. PLoS ONE, 7(9), e44566. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0044566
Becker, Karen; Reim, Daniel; Novotny, Alexander; Zum Büschenfelde, Christian Meyer; Engel, Jutta; Friess, Helmut; Höfler, Heinz; Langer, Rupert (2012). Proposal for a multifactorial prognostic score that accurately classifies 3 groups of gastric carcinoma patients with different outcomes after neoadjuvant chemotherapy and surgery. Annals of surgery, 256(6), pp. 1002-7. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SLA.0b013e318262a591
Slotta-Huspenina, Julia; Berg, Daniela; Bauer, Karina; Wolff, Claudia; Malinowsky, Katharina; Bauer, Lukas; Drecoll, Enken; Bettstetter, Marcus; Feith, Marcus; Walch, Axel; Höfler, Heinz; Becker, Karl-Friedrich; Langer, Rupert (2012). Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas. PLoS ONE, 7(7), e41420. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0041420
Bauer, Karina; Nitsche, Ulrich; Slotta-Huspenina, Julia; Drecoll, Enken; von Weyhern, Claus Hann; Rosenberg, Robert; Höfler, Heinz; Langer, Rupert (2012). High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer. Cellular oncology, 35(3), pp. 197-205. Dordrecht: Springer 10.1007/s13402-012-0079-3
Seiz, Lina; Dorn, Julia; Kotzsch, Matthias; Walch, Axel; Grebenchtchikov, Nicolai I; Gkazepis, Apostolos; Schmalfeldt, Barbara; Kiechle, Marion; Bayani, Jane; Diamandis, Eleftherios P; Langer, Rupert; Sweep, Fred C G J; Schmitt, Manfred; Magdolen, Viktor (2012). Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients. Biological chemistry, 393(5), pp. 391-401. Berlin: De Gruyter 10.1515/hsz-2011-0264
Regel, Ivonne; Merkl, Lisa; Friedrich, Teresa; Burgermeister, Elke; Zimmermann, Wolfgang; Einwächter, Henrik; Herrmann, Ken; Langer, Rupert; Röcken, Christoph; Hofheinz, Ralf; Schmid, Roland; Ebert, Matthias P (2012). Pan-histone deacetylase inhibitor panobinostat sensitizes gastric cancer cells to anthracyclines via induction of CITED2. Gastroenterology, 143(1), 99-109.e10. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2012.03.035
Meding, Stephan; Balluff, Benjamin; Elsner, Mareike; Schöne, Cédrik; Rauser, Sandra; Nitsche, Ulrich; Maak, Matthias; Schäfer, Alexander; Hauck, Stefanie M; Ueffing, Marius; Langer, Rupert; Höfler, Heinz; Friess, Helmut; Rosenberg, Robert; Walch, Axel (2012). Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer. Journal of pathology, 228(4), pp. 459-470. Chichester: Wiley 10.1002/path.4021
Berezowska, Sabina; Tomoka, Tamiwe; Kamiza, Steve; Milner, Danny A; Langer, Rupert (2012). Surgical pathology in sub-Saharan Africa--volunteering in Malawi. Virchows Archiv, 460(4), pp. 363-70. Berlin: Springer-Verlag 10.1007/s00428-012-1217-z
Elsner, Mareike; Rauser, Sandra; Maier, Stefan; Schöne, Cédrik; Balluff, Benjamin; Meding, Stephan; Jung, Gerhard; Nipp, Martin; Sarioglu, Hakan; Maccarrone, Giuseppina; Aichler, Michaela; Feuchtinger, Annette; Langer, Rupert; Jütting, Uta; Feith, Marcus; Küster, Bernhard; Ueffing, Marius; Zitzelsberger, Horst; Höfler, Heinz and Walch, Axel (2012). MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma. Journal of proteomics, 75(15), pp. 4693-704. Amsterdam: Elsevier 10.1016/j.jprot.2012.02.012
Troeltzsch, Matthias; Stimmer, Herbert; Langer, Rupert; Troeltzsch, Markus; Steiner, Timm; Wolff, Klaus-Dietrich (2012). High-grade supraclavicular soft tissue sarcoma as secondary malignancy after successful treatment of acute myeloid leukemia: case report and literature review. Journal of oral and maxillofacial surgery, 70(9), pp. 2211-7. Maryland Heights, Mo.: Elsevier 10.1016/j.joms.2011.10.008
Meding, Stephan; Nitsche, Ulrich; Balluff, Benjamin; Elsner, Mareike; Rauser, Sandra; Schöne, Cédrik; Nipp, Martin; Maak, Matthias; Feith, Marcus; Ebert, Matthias P; Friess, Helmut; Langer, Rupert; Höfler, Heinz; Zitzelsberger, Horst; Rosenberg, Robert; Walch, Axel (2012). Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging. Journal of proteome research, 11(3), pp. 1996-2003. Washington, D.C.: American Chemical Society 10.1021/pr200784p
Ebert, Matthias P A; Tänzer, Marc; Balluff, Benjamin; Burgermeister, Elke; Kretzschmar, Antje Karen; Hughes, David J; Tetzner, Reimo; Lofton-Day, Catherine; Rosenberg, Robert; Reinacher-Schick, Anke C; Schulmann, Karsten; Tannapfel, Andrea; Hofheinz, Ralf; Röcken, Christoph; Keller, Gisela; Langer, Rupert; Specht, Katja; Porschen, Rainer; Stöhlmacher-Williams, Jan; Schuster, Tibor; ... (2012). TFAP2E-DKK4 and chemoresistance in colorectal cancer. New England journal of medicine NEJM, 366(1), pp. 44-53. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMoa1009473
Keller, Gisela; Geist, Birgit; Slotta-Huspenina, Julia; Langer, Rupert; Nagl, Florian; Fend, Falko; Höfler, Heinz; Perren, Aurel (2009). Novel multiple, monoallelic KRAS mutations at codon 12 and 13. International journal of cancer, 125(11), pp. 2744-5. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.24635
Voland, Petra; Besig, Sophie; Rad, Roland; Braun, Thomas; Baur, Dorothee M.; Perren, Aurel; Langer, Rupert; Höfler, Heinz; Prinz, Christian (2009). Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival. Neuroendocrinology, 89(1), pp. 66-78. Karger 10.1159/000151482
Kröll, Dino; Erdem, Suna; Haltmeier, Tobias; Langer, Rupert; Candinas, Daniel; Seiler, Christian A. (2017). Does the extent of lymphadenectomy have an impact on in-hospital mortality and reoperations after TME for esophageal cancer? (Unpublished). In: Schweizerische Gesellschaft für Chirurgie Kongress 2017. Bern. 31.5.- 2.6.2017.
Noser, Laura; Kröll, Dino; Erdem, Suna; Storni, Federico Lorenzo; Arnold, Dominik; Dislich, Bastian; Zlobec, Inti; Seiler, Christian A.; Langer, Rupert (2017). The 8th edition of the AJCC TNM staging system shows slightly improved, but still not perfect prognostication for esophageal carcinomas treated by neoadjuvant therapy followed by surgery (Unpublished). In: Schweizerische Gesellschaft für Chirurgie Kongress 2017. Bern. 31.5.-2.6.2017.
Stein, Alexandra; Blank, Annika; Guldener, Lars; Dislich, Bastian; Kröll, Dino; Seiler, Christian A.; Langer, Rupert (2015). High intratumoral levels of FoxP3+ lymphocytes are associated with better prognosis in primary resected esophageal adenocarcinomas. (Submitted). In: Schweizer Pathologentag.
Moghaddam, Negahnaz; Langer, Rupert; Ross, Steffen; Müller, Felix; Lösch, Sandra (13 June 2014). A Case Of A Malignant Bone Tumor In Iron Age Switzerland (Unpublished). In: 98. Jahrestagung der Deutschen Gesellschaft für Pathologie e.V.. Berlin, Germany. 12.-15.06.2014.
Zlobec, Inti; Kölzer, Viktor; Dawson, Heather; Langer, Rupert; Karamitopoulou, Evanthia; Lugli, Alessandro (2013). Investigation of IL23 (p19, p40) and IL23R highlights nuclear IL23p19 expression as a marker of indolent tumor features and favorable outcome in colorectal cancer patients. Virchows Archiv, 463(2), pp. 139-140. Springer 10.1007/s00428-013-1444-y
Berezowska, Sabina Anna; Langer, Rupert (2013). Initiation of a tumor tissue-bank in Malawi. Virchows Archiv, 463(2), p. 105. Springer
