04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR) > DCR Unit Maurice E. Müller Building > Forschungsgruppe Knochenbiologie & Orthopädische Forschung

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Number of items at this level: 57.

2017

Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2017). Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Pflügers Archiv : European journal of physiology, 469(2), pp. 225-233. Springer 10.1007/s00424-016-1923-5

2016

Saulacic, Nikola; Nakahara, Ken; Iizuka, Tateyuki; Haga-Tsujimura, Maiko; Hofstetter, Wilhelm; Scolozzi, Paolo (2016). Comparison of two protocols of periosteal distraction osteogenesis in a rabbit calvaria model. Journal of biomedical materials research. Part B - applied biomaterials, 104(6), pp. 1121-1131. John Wiley & Sons 10.1002/jbm.b.33461

Xie, Wenjie; Dolder, Silvia; Siegrist, Mark; Wetterwald, Antoinette; Hofstetter, Wilhelm (2016). Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells. Calcified tissue international, 99(2), pp. 142-154. Springer 10.1007/s00223-016-0129-3

Xie, Wenjie; Lorenz, Sebastian; Dolder, Silvia; Hofstetter, Wilhelm (2016). Extracellular Iron is a Modulator of the Differentiation of Osteoclast Lineage Cells. Calcified tissue international, 98(3), pp. 275-283. Springer 10.1007/s00223-015-0087-1

Schaller, Benoît; Saulacic, Nikola; Imwinkelried, Thomas; Beck, Stefan; Liu, Edwin Wei Yang; Gralla, Jan; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2016). In vivo degradation of magnesium plate/screw osteosynthesis implant systems: Soft and hard tissue response in a calvarial model in miniature pigs. Journal of cranio-maxillo-facial surgery, 44(3), pp. 309-317. Elsevier 10.1016/j.jcms.2015.12.009

Aeberli, Daniel; Kamgang, Richard; Balani, Deepak; Hofstetter, Wilhelm; Villiger, Peter; Seitz, Michael (2016). Regulation of peripheral classical and non-classical monocytes on infliximab treatment in patients with rheumatoid arthritis and ankylosing spondylitis. RMD open, 2(1), e000079. BMJ Publishing Group 10.1136/rmdopen-2015-000079

Schaller, Benoît; Saulacic, Nikola; Beck, Stefan; Imwinkelried, Thomas; Goh, Bee Tin; Nakahara, Ken; Hofstetter, Wilhelm; Iizuka, Tateyuki (2016). In vivo degradation of a new concept of magnesium-based rivet-screws in the minipig mandibular bone. Materials Science and Engineering: C, 69, pp. 247-254. Elsevier 10.1016/j.msec.2016.06.085

Stok, Kathryn S; Besler, Bryce A; Steiner, Thomas H; Villarreal Escudero, Ana V; Zulliger, Martin A; Wilke, Markus; Atal, Kailash; Quintin, Aurelie; Koller, Bruno; Müller, Ralph; Nesic, Dobrila (2016). Three-Dimensional Quantitative Morphometric Analysis (QMA) for In Situ Joint and Tissue Assessment of Osteoarthritis in a Preclinical Rabbit Disease Model. PLoS ONE, 11(1), e0147564. Public Library of Science 10.1371/journal.pone.0147564

2015

Schär, Michael O; Diaz-Romero, Jose; Kohl, Sandro; Zumstein, Matthias A; Nesic, Dobrila (2015). Platelet-rich concentrates differentially release growth factors and induce cell migration in vitro. Clinical orthopaedics and related research, 473(5), pp. 1635-1643. Springer 10.1007/s11999-015-4192-2

Jülke, Henriette; Mainil-Varlet, Pierre; Jakob, Roland P; Brehm, Walter; Schäfer, Birgit; Nesic, Dobrila (2015). The Role of Cells in Meniscal Guided Tissue Regeneration: A Proof of Concept Study in a Goat Model. Cartilage, 6(1), pp. 20-29. Sage 10.1177/1947603514548213

Albano, Giuseppe; Moor, Matthias; Dolder, Silvia; Siegrist, Mark; Wagner, Carsten A.; Biber, Jürg; Hernando, Nati; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2015). Sodium-Dependent Phosphate Transporters in Osteoclast Differentiation and Function. PLoS ONE, 10(4), e0125104. Public Library of Science 10.1371/journal.pone.0125104

Tekari, Adel; Luginbuehl, Reto; Hofstetter, Wilhelm; Egli, Rainer (2015). Transforming growth factor beta signaling is essential for the autonomous formation of cartilage-like tissue by expanded chondrocytes. PLoS ONE, 10(3), e0120857. Public Library of Science 10.1371/journal.pone.0120857

2014

Choy, John; Albers, Christoph; Siebenrock, Klaus-Arno; Dolder, Silvia; Hofstetter, Wilhelm; Klenke, Frank M. (2014). Incorporation of RANKL promotes osteoclast formation and osteoclast activity on β-TCP ceramics. Bone, 69, pp. 80-88. Elsevier 10.1016/j.bone.2014.09.013

Tekari, Adel; Luginbuehl, Reto; Hofstetter, Wilhelm; Egli, Rainer (2014). Chondrocytes expressing intracellular collagen type II enter the cell cycle and co-express collagen type I in monolayer culture. Journal of orthopaedic research, 32(11), pp. 1503-1511. Wiley 10.1002/jor.22690

Diaz Romero, Jose; Quintin, Aurelie; Schoenholzer, Eric; Pauli, Chantal; Despont, Alain; Zumstein, Matthias; Kohl, Sandro; Nesic, Dobrila (2014). S100A1 and S100B expression patterns identify differentiation status of human articular chondrocytes. Journal of cellular physiology, 229(8), pp. 1106-1117. Wiley 10.1002/jcp.24547

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

2013

Leunig, M.; Jüni, P.; Werlen, S.; Limacher, A.; Nüesch, E.; Pfirrmann, C. W.; Trelle, S.; Odermatt, A.; Hofstetter, Wilhelm; Ganz, R.; Reichenbach, Stephan (2013). Prevalence of cam and pincer-type deformities on hip MRI in an asymptomatic young Swiss female population: a cross-sectional study. OSTEOARTHRITIS AND CARTILAGE, 21(4), pp. 544-550. Elsevier 10.1016/j.joca.2013.01.003

Albers, Christoph E; Hofstetter, Wilhelm; Siebenrock, Klaus A; Landmann, Regine; Klenke, Frank M. (2013). In vitro cytotoxicity of silver nanoparticles on osteoblasts and osteoclasts at antibacterial concentrations. Nanotoxicology, 7(1), pp. 30-36. London: Informa Healthcare 10.3109/17435390.2011.626538

Montjovent, Marc-Oliver; Siegrist, Mark; Klenke, Frank M; Wetterwald, Antoinette; Dolder, Silvia; Hofstetter, Wilhelm (2013). Expression of antagonists of WNT and BMP signaling after non-rigid fixation of osteotomies. Bone, 53(1), pp. 79-86. New York, N.Y.: Elsevier 10.1016/j.bone.2012.11.027

Braun, T; Lepper, J; Ruiz Heiland, G; Hofstetter, W; Siegrist, M; Lezuo, P; Gaestel, M; Rumpler, M; Thaler, R; Klaushofer, K; Distler, JH; Schett, G; Zwerina, J (2013). Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover. Journal of bone and mineral research, 4(4), pp. 936-947. Hoboken, N.J.: Wiley-Blackwell 10.1002/jbmr.1816

Hofstetter, Wilhelm; Sehr, Harald; De Wild, Michael; Portenier, Jeannette; Gobrecht, Jens; Hunziker, Ernst Bruno (2013). Modulation of human osteoblasts by metal surface chemistry. Journal of biomedical materials research. Part A, 101(8), pp. 2355-2364. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.34541

Choy, John; Hofstetter, Wilhelm; Klenke, Frank M. (2013). RANKL immobilized on β-TCP induces and maintains osteoclast formation. Bone Abstracts, 1, PP227. Bioscientifica 10.1530/boneabs.1.PP227

2012

Albers, Christoph E; Hofstetter, Wilhelm; Sebald, Hans-Jörg; Sebald, Walter; Siebenrock, Klaus A; Klenke, Frank M (2012). L51P - A BMP2 variant with osteoinductive activity via inhibition of Noggin. Bone, 51(3), pp. 401-6. New York, N.Y.: Elsevier 10.1016/j.bone.2012.06.020

Sebald, Hans-Jörg; Klenke, Frank M; Siegrist, Mark; Albers, Christoph E; Sebald, Walter; Hofstetter, Wilhelm (2012). Inhibition of endogenous antagonists with an engineered BMP-2 variant increases BMP-2 efficacy in rat femoral defect healing. Acta biomaterialia, 8(10), pp. 3816-20. Amsterdam: Elsevier 10.1016/j.actbio.2012.06.036

Balani, Deepak; Aeberli, Daniel; Hofstetter, Willy; Seitz, Michael (2012). Interleukin-17A stimulates granulocyte-macrophage colony-stimulating factor release by murine osteoblasts in the presence of 1,25-dihydroxyvitamin D(3) and inhibits murine osteoclast development in vitro. Arthritis & rheumatism, 65(2), pp. 236-246. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.37762

Ruiz-Heiland, G; Horn, A; Zerr, P; Hofstetter, W; Baum, W; Stock, M; Distler, JH; Nimmerjahn, F; Schett, G; Zwerina, J (2012). Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis. Annals of the rheumatic diseases, 3(3), pp. 400-407. London: BMJ Publishing Group 10.1136/ard.2010.148262

2011

Broggini, N; Hofstetter, W; Hunziker, E; Bosshardt, DD; Bornstein, MM; Seto, I; Weibrich, G; Buser, D (2011). The Influence of PRP on Early Bone Formation in Membrane Protected Defects. A Histological and Histomorphometric Study in the Rabbit Calvaria. Clinical implant dentistry and related research, 13(1), pp. 1-12. Oxford: Blackwell 10.1111/j.1708-8208.2009.00266.x

Reichenbach, Stephan; Leunig, Michael; Werlen, Stefan; Nüesch, Eveline; Pfirrmann, Christian W; Bonel, Harald; Odermatt, Alex; Hofstetter, Willy; Ganz, Reinhold; Jüni, Peter (2011). Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage: a cross-sectional study in young men. Arthritis & rheumatism, 63(12), pp. 4023-4030. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.30589

Atanga, Elvis; Dolder, Silvia; Dauwalder, Tina; Wetterwald, Antoinette; Hofstetter, Willy (2011). TNFα inhibits the development of osteoclasts through osteoblast-derived GM-CSF. Bone, 49(5), pp. 1090-100. New York, N.Y.: Elsevier 10.1016/j.bone.2011.08.003

Bastian, Johannes Dominik; Egli, Rainer J; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2011). Chondrocytes within osteochondral grafts are more resistant than osteoblasts to tissue culture at 37°C. Journal of investigative surgery, 24(1), pp. 28-34. New York, N.Y.: Taylor & Francis 10.3109/08941939.2010.523511

2010

Wernike, E; Montjovent, MO; Liu, Y; Wismeijer, D; Hunziker, EB; Siebenrock, KA; Hofstetter, W; Klenke, FM (2010). VEGF incorporated into calcium phosphate ceramics promotes vascularisation and bone formation in vivo. European cells & materials eCM, 19, pp. 30-40. Aberystwyth (UK): University of Wales

Hofstetter, Willy; Siegrist, Mark; Simonin, Alexandre; Bonny, Olivier; Fuster, Daniel G (2010). Sodium/hydrogen exchanger NHA2 in osteoclasts: subcellular localization and role in vitro and in vivo. Bone, 47(2), pp. 331-340. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.605

Wernike, E; Hofstetter, W; Liu, Y; Wu, G; Sebald, HJ; Wismeijer, D; Hunziker, EB; Siebenrock, KA; Klenke, FM (2010). Long-term cell-mediated protein release from calcium phosphate ceramics. Journal of biomedical materials research, 92(2), pp. 463-74. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.32411

Bastian, Johannes Dominik; Egli, RJ; Hofstetter, W; Leunig, M (2010). Chondrocyte function after osteochondral transfer: comparison of concave and plane punches. Archives of orthopaedic and trauma surgery, 130(3), pp. 341-6. Berlin: Springer 10.1007/s00402-009-0867-z

Reichenbach, S; Jüni, P; Werlen, S; Nüesch, E; Pfirrmann, CW; Trelle, S; Odermatt, A; Hofstetter, W; Ganz, R; Leunig, M (2010). Prevalence of cam-type deformity on hip magnetic resonance imaging in young males: a cross-sectional study. Arthritis & rheumatism, 62(9), pp. 1319-1327. Hoboken, N.J.: Wiley-Blackwell 10.1002/acr.20198

Egermann, M; Heil, P; Tami, A; Ito, K; Janicki, P; Von Rechenberg, B; Hofstetter, W; Richards, PJ (2010). Influence of defective bone marrow osteogenesis on fracture repair in an experimental model of senile osteoporosis. Journal of orthopaedic research, 28(6), pp. 798-804. Hoboken, N.J.: Wiley 10.1002/jor.21041

2009

Bastian, J. D.; Egli, R. J.; Ganz, R.; Hofstetter, W.; Leunig, M. (2009). Differential response of porcine osteoblasts and chondrocytes in cell or tissue culture after 5-aminolevulinic acid-based photodynamic therapy. Osteoarthritis and cartilage, 17(4), pp. 539-46. Amsterdam: Elsevier 10.1016/j.joca.2008.08.005

Leunig, M; Reichenbach, S; Trelle, S; Werlen, S; Odermatt, A; Hofstetter, W (2009). Hueft-Impingment: ein neuer Risikofaktor oder Coxarthrose? Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 2009(9), pp. 708-710. Basel: EMH Editores Medicorum Helveticorum

2008

Klenke, FM; Liu, Y; Yuan, H; Hunziker, EB; Siebenrock, KA; Hofstetter, W (2008). Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo. Journal of biomedical materials research. Part A, 85(3), pp. 777-86. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.31559

Gengenbacher, M; Sebald, H-J; Villiger, P M; Hofstetter, W; Seitz, M (2008). Infliximab inhibits bone resorption by circulating osteoclast precursor cells in patients with Rheumatoid Arthritis and Ankylosing Spondylitis. Annals of the rheumatic diseases, 67(5), pp. 620-4. London: BMJ Publishing Group 10.1136/ard.2007.076711

Fraitzl, Christian R; Egli, Rainer J; Wingenfeld, Carsten; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2008). Time course of biological activity in fresh murine osteochondral allografts paralleled to the recipient's immune response. Journal of investigative surgery, 21(3), pp. 109-17. New York, N.Y.: Taylor & Francis 10.1080/08941930802043540

Egli, Rainer J; Di Criscio, Agostino; Hempfing, Axel; Schoeniger, Ralf; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2008). In vitro resistance of articular chondrocytes to 5-Aminolevulinic acid based photodynamic therapy. Lasers in surgery and medicine, 40(4), pp. 282-90. Hoboken, N.J.: Wiley-Liss 10.1002/lsm.20625

Egli, Rainer J; Bastian, Johannes D; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2008). Hypoxic expansion promotes the chondrogenic potential of articular chondrocytes. Journal of orthopaedic research, 26(7), pp. 977-85. Hoboken, N.J.: Wiley 10.1002/jor.20603

Wagner, S; Gollwitzer, H; Wernicke, D; Langer, R; Siebenrock, KA; Hofstetter, W (2008). Interface membrane fibroblasts around aseptically loosened endoprostheses express MMP-13. Journal of orthopaedic research, 26(2), pp. 143-52. Hoboken, N.J.: Wiley 10.1002/jor.20494

Wernike, Ellen; Li, Zhen; Alini, Mauro; Grad, Sibylle (2008). Effect of reduced oxygen tension and long-term mechanical stimulation on chondrocyte-polymer constructs. Cell and tissue research, 331(2), pp. 473-83. Heidelberg: Springer 10.1007/s00441-007-0500-9

2007

Egli, Rainer J; Schober, Martin; Hempfing, Axel; Ganz, Reinhold; Hofstetter, Willy; Leunig, Michael (2007). Sensitivity of osteoblasts, fibroblasts, bone marrow cells, and dendritic cells to 5-aminolevulinic acid based photodynamic therapy. Journal of photochemistry and photobiology. B - biology, 89(2-3), pp. 70-7. Amsterdam: Elsevier 10.1016/j.jphotobiol.2007.09.005

2006

Wagner, Susanne; Hofstetter, Willy; Chiquet, Matthias; Mainil-Varlet, Pierre; Stauffer, Edouard; Jansson, Volkmar; Siebenrock, Klaus A (2006). Femoro-azetabuläres Impingement: Eine präarthrotische Deformität? Zeitschrift für Orthopädie und ihre Grenzgebiete, 144(3), pp. 248-51. Stuttgart: Thieme

Dolder, Silvia; Hofstetter, Willy; Wetterwald, Antoinette; Mühlbauer, Roman C; Felix, Rolf (2006). Effect of monoterpenes on the formation and activation of osteoclasts in vitro. Journal of bone and mineral research, 21(4), pp. 647-55. Hoboken, N.J.: Wiley-Blackwell 10.1359/JBMR.060111

Balga, Renate; Wetterwald, Antoinette; Portenier, Jeannette; Dolder, Silvia; Mueller, Christoph; Hofstetter, Willy (2006). Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro. Bone, 39(2), pp. 325-35. New York, N.Y.: Elsevier 10.1016/j.bone.2006.02.056

Jost-Albrecht, Katrin; Hofstetter, Willy (2006). Gene expression by human monocytes from peripheral blood in response to exposure to metals. Journal of biomedical materials research. Part B - applied biomaterials, 76(2), pp. 449-55. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.b.30389

Lau, Y S; Sabokbar, A; Giele, H; Cerundolo, V; Hofstetter, W; Athanasou, N A (2006). Malignant melanoma and bone resorption. British journal of cancer, 94(10), pp. 1496-503. Basingstoke: Nature Publishing Group 10.1038/sj.bjc.6603103

2005

Sommer, Beatrice; Felix, Rolf; Sprecher, Christoph; Leunig, Michael; Ganz, Reinhold; Hofstetter, Willy (2005). Wear particles and surface topographies are modulators of osteoclastogenesis in vitro. Journal of biomedical materials research. Part A, 72(1), pp. 67-76. Hoboken, N.J.: John Wiley & Sons 10.1002/jbm.a.30202

Wetli, Herbert A; Brenneisen, Rudolf; Tschudi, Ingrid; Langos, Manuela; Bigler, Peter; Sprang, Thomas; Schürch, Stefan; Mühlbauer, Roman C (2005). A gamma-glutamyl peptide isolated from onion (Allium cepa L.) by bioassay-guided fractionation inhibits resorption activity of osteoclasts. Journal of agricultural and food chemistry, 53(9), pp. 3408-14. Columbus, Ohio: American Chemical Society 10.1021/jf040457l

Lazzarato, Loretta; Rolando, Barbara; Lolli, Marco L; Tron, Gian Cesare; Fruttero, Roberta; Gasco, Alberto; Deleide, Guido; Guenther, Harald L (2005). Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption. Journal of medicinal chemistry, 48(5), pp. 1322-9. Easton, Pa.: American Chemical Society 10.1021/jm040830d

2004

Spichiger, Miriam; Mühlbauer, Roman C; Brenneisen, Rudolf (2004). Determination of menthol in plasma and urine of rats and humans by headspace solid phase microextraction and gas chromatography--mass spectrometry. Journal of chromatography. B - analytical technologies in the biomedical and life sciences, 799(1), pp. 111-7. New York, N.Y.: Elsevier 10.1016/j.jchromb.2003.10.022

Rothenfluh, Dominique A; Demhartner, Thomas J; Fraitzl, Christian R; Cecchini, Marco G; Ganz, Reinhold; Leunig, Michael (2004). Potential role of pre-existing blood vessels for vascularization and mineralization of osteochondral grafts: an intravital microscopic study in mice. Acta orthopaedica Scandinavica, 75(3), pp. 359-65. Basingstoke, UK: Taylor & Francis 10.1080/00016470410001330

1991

Mühlbauer, R. C.; Bauss, F.; Schenk, R.; Janner, M.; Bosies, E.; Strein, K.; Fleisch, H. (1991). BM 21.0955, a potent new bisphosphonate to inhibit bone resorption. Journal of bone and mineral research, 6(9), pp. 1003-1011. Wiley-Blackwell

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