Jakob, Stephan

No

Krejci, Vladimir; Hiltebrand, Luzius B; Jakob, Stephan M; Takala, Jukka; Sigurdsson, Gisli H (2007). Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow. Critical care, 11(6), R129. London: BioMed Central 10.1186/cc6197

Yes

Sivapalan, Praleene; Kaas-Hansen, Benjamin Skov; Meyhoff, Tine Sylvest; Hjortrup, Peter Buhl; Kjær, Maj-Brit N; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders; Granholm, Anders (2024). Effects of IV fluid restriction according to site-specific intensity of standard fluid treatment-protocol. Acta anaesthesiologica Scandinavica, 68(7), pp. 975-982. Wiley 10.1111/aas.14423

Bachmann, Kaspar F; Haenggi, Matthias; Jakob, Stephan M; Takala, Jukka; Gattinoni, Luciano; Berger, David (2024). Comment on: "A novel 'shunt fraction' method to derive native cardiac output during liberation from central VA ECMO" by Lim, HS. ESC Heart Failure, 11(4), pp. 2464-2466. Wiley 10.1002/ehf2.14804

Moser, André; Raj, Rahul; Reinikainen, Matti; Jakob, Stephan M; Takala, Jukka (2024). Effect of mortality prediction models on resource use benchmarking of intensive care units. Journal of critical care, 82(154814), p. 154814. Elsevier 10.1016/j.jcrc.2024.154814

Pölkki, Anssi; Moser, André; Raj, Rahul; Takala, Jukka; Bendel, Stepani; Jakob, Stephan M; Reinikainen, Matti (2024). The authors reply. Critical care medicine, 52(4), e217-e218. Wolters Kluwer Health 10.1097/CCM.0000000000006205

Pölkki, Anssi; Moser, André; Raj, Rahul; Takala, Jukka; Bendel, Stepani; Jakob, Stephan M; Reinikainen, Matti (2024). The Influence of Potential Organ Donors on Standardized Mortality Ratios and ICU Benchmarking. Critical care medicine, 52(3), pp. 387-395. Lippincott Williams & Wilkins 10.1097/CCM.0000000000006098

Meyhoff, Tine Sylvest; Granholm, Anders; Hjortrup, Peter Buhl; Sivapalan, Praleene; Lange, Theis; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders (2024). Albumin use in patients with septic shock-Post-hoc analyses of an international randomised fluid trial. Acta anaesthesiologica Scandinavica, 68(3), pp. 372-384. Wiley 10.1111/aas.14359

Raj, Rahul; Moser, André; Starkopf, Joel; Reinikainen, Matti; Varpula, Tero; Jakob, Stephan M; Takala, Jukka (2024). Variation in Severity-Adjusted Resource use and Outcome for Neurosurgical Emergencies in the Intensive Care Unit. Neurocritical care, 40(1), pp. 251-261. Springer 10.1007/s12028-023-01723-3

Sivapalan, Praleene; Meyhoff, Tine Sylvest; Hjortrup, Peter Buhl; Lange, Theis; Kaas-Hansen, Benjamin Skov; Kjaer, Maj-Brit N; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders; Granholm, Anders (2024). Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock-Bayesian analyses of the CLASSIC trial. Acta anaesthesiologica Scandinavica, 68(2), pp. 236-246. Wiley 10.1111/aas.14345

Pitton, Melissa; Valente, Luca G; Oberhaensli, Simone; Casanova, Carlo; Sendi, Parham; Schnegg, Bruno; Jakob, Stephan M; Cameron, David R; Que, Yok-Ai; Fürholz, Monika (2023). Dynamics of bacterial pathogens at the driveline exit site in patients with ventricular assist devices: a prospective, observational, single-centre cohort study. The Journal of heart and lung transplantation, 42(10), pp. 1445-1454. Elsevier 10.1016/j.healun.2023.05.016

Naef, Aileen C; Jeitziner, Marie-Madlen; Jakob, Stephan M; Müri, René M; Nef, Tobias (2023). Creating Custom Immersive 360-Degree Videos for Use in Clinical and Nonclinical Settings: Tutorial. JMIR medical education, 9, e42154. JMIR Publications 10.2196/42154

Meyhoff, Tine Sylvest; Granholm, Anders; Hjortrup, Peter Buhl; Sivapalan, Praleene; Lange, Theis; Laake, Jon Henrik; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu L N G; Møller, Morten Hylander; Perner, Anders (2023). Albumin administration in septic shock-Protocol for post-hoc analyses of data from a multicentre RCT. Acta anaesthesiologica Scandinavica, 67(8), pp. 1128-1136. Wiley-Blackwell 10.1111/aas.14280

Kjær, Maj-Brit Nørregaard; Meyhoff, Tine Sylvest; Sivapalan, Praleene; Granholm, Anders; Hjortrup, Peter Buhl; Madsen, Martin Bruun; Møller, Morten Hylander; Egerod, Ingrid; Wetterslev, Jørn; Lange, Theis; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M; Nalos, Marek; Ostermann, Marlies; Gould, Doug; Cecconi, Maurizio; Malbrain, Manu L N G; Ahlstedt, Christian; Kiel, Louise Bendix; ... (2023). Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock. Intensive care medicine, 49(7), pp. 820-830. Springer 10.1007/s00134-023-07114-8

Shekar, Kiran; Abdul-Aziz, Mohd H; Cheng, Vesa; Burrows, Fay; Buscher, Hergen; Cho, Young-Jae; Corley, Amanda; Diehl, Arne; Gilder, Eileen; Jakob, Stephan M; Kim, Hyung-Sook; Levkovich, Bianca J; Lim, Sung Yoon; McGuinness, Shay; Parke, Rachael; Pellegrino, Vincent; Que, Yok-Ai; Reynolds, Claire; Rudham, Sam; Wallis, Steven C; ... (2023). Antimicrobial Exposures in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation. American journal of respiratory and critical care medicine, 207(6), pp. 704-720. American Thoracic Society 10.1164/rccm.202207-1393OC

Granholm, Anders; Munch, Marie Warrer; Andersen-Ranberg, Nina; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Venkatesh, Balasubramanian; Jha, Vivekanand; Rubenson, Rebecka Wahlin; Jakob, Stephan M; Cioccari, Luca; Møller, Morten Hylander; Perner, Anders (2023). Heterogenous treatment effects of dexamethasone 12 mg vs. 6 mg in patients with COVID-19 and severe hypoxaemia - post hoc exploratory analyses of the COVID STEROID 2 trial. Acta anaesthesiologica Scandinavica, 67(2), pp. 195-205. Wiley 10.1111/aas.14167

Schlapbach, Luregn J; Zimmermann, Elisa A; Meylan, Sylvain; Stocker, Martin; Suter, Peter M; Jakob, Stephan M (2023). Swiss Sepsis National Action Plan: A coordinated national action plan to stop sepsis-related preventable deaths and to improve the support of people affected by sepsis in Switzerland. Frontiers in medicine, 10(1114546), p. 1114546. Frontiers 10.3389/fmed.2023.1114546

Naef, Aileen C; Gerber, Stephan M; Single, Michael; Müri, René M; Haenggi, Matthias; Jakob, Stephan M; Jeitziner, Marie-Madlen; Nef, Tobias (2023). Effects of immersive virtual reality on sensory overload in a random sample of critically ill patients. Frontiers in medicine, 10(1268659), p. 1268659. Frontiers 10.3389/fmed.2023.1268659

Cameron, David R; Pitton, Melissa; Oberhaensli, Simone; Schlegel, Katja; Prod'hom, Guy; Blanc, Dominique S; Jakob, Stephan M; Que, Yok-Ai (2022). Parallel Evolution of Pseudomonas aeruginosa during a Prolonged ICU-Infection Outbreak. Microbiology spectrum, 10(6), e0274322. American Society for Microbiology 10.1128/spectrum.02743-22

Heliste, Maria; Pettilä, Ville; Berger, David; Jakob, Stephan M; Wilkman, Erika (2022). Beta-blocker treatment in the critically ill: a systematic review and meta-analysis. Annals of medicine, 54(1), pp. 1994-2010. Taylor & Francis 10.1080/07853890.2022.2098376

Lång, Maarit; Jakob, Stephan M; Takala, Riikka; Lyngbakken, Magnus N; Turpeinen, Anu; Omland, Torbjørn; Merz, Tobias M; Wiegand, Jan; Grönlund, Juha; Rahi, Melissa; Valtonen, Mika; Koivisto, Timo; Røsjø, Helge; Bendel, Stepani (2022). The prevalence of cardiac complications and their impact on outcomes in patients with non-traumatic subarachnoid hemorrhage. Scientific reports, 12(1), p. 20109. Springer Nature 10.1038/s41598-022-24675-8

Carrara, Marta; Antenucci, Pietro; Liu, Shengchen; Kohler, Andreas; Langer, Rupert; Jakob, Stephan M; Ferrario, Manuela (2022). Autonomic and circulatory alterations persist despite adequate resuscitation in a 5-day sepsis swine experiment. Scientific Reports, 12(1), p. 19279. Nature Publishing Group 10.1038/s41598-022-23516-y

Liu, Shengchen; Kohler, Andreas; Langer, Rupert; Jakob, Manuel O; Salm, Lilian; Blank, Annika; Beldi, Guido; Jakob, Stephan M (2022). Hepatic blood flow regulation but not oxygen extraction capability is impaired in prolonged experimental abdominal sepsis. American journal of physiology - gastrointestinal and liver physiology, 323(4), G348-G361. American Physiological Society 10.1152/ajpgi.00109.2022

Draxler, Domink F; Brodard, Justine; Zante, Björn; Jakob, Stephan M; Wiegand, Jan; Kremer Hovinga, Johanna A; Angelillo-Scherrer, Anne; Rovo, Alicia (2022). The potential impact of Covid-19 on the capacity of routine laboratory tests to detect heparin-induced thrombocytopenia. Thrombosis journal, 20(1), p. 55. BioMed Central 10.1186/s12959-022-00411-0

Pitton, Melissa; Oberhaensli, Simone; Appiah, Fiona; Pagani, Jean-Luc; Fournier, Anne; Jakob, Stephan M; Que, Yok-Ai; Cameron, David R (2022). Mutation to ispA Produces Stable Small-Colony Variants of Pseudomonas aeruginosa That Have Enhanced Aminoglycoside Resistance. Antimicrobial agents and chemotherapy, 66(7), e0062122. American Society for Microbiology 10.1128/aac.00621-22

Takala, Jukka; Moser, André; Reinikainen, Matti; Varpula, Tero; Raj, Rahul; Jakob, Stephan M (2022). Impact of cardiac surgery and neurosurgery patients on variation in severity-adjusted resource use in intensive care units. Journal of critical care, 71, p. 154110. Elsevier 10.1016/j.jcrc.2022.154110

Wendel-Garcia, Pedro David; Moser, André; Jeitziner, Marie-Madlen; Aguirre-Bermeo, Hernán; Arias-Sanchez, Pedro; Apolo, Janina; Roche-Campo, Ferran; Franch-Llasat, Diego; Kleger, Gian-Reto; Schrag, Claudia; Pietsch, Urs; Filipovic, Miodrag; David, Sascha; Stahl, Klaus; Bouaoud, Souad; Ouyahia, Amel; Fodor, Patricia; Locher, Pascal; Siegemund, Martin; Zellweger, Nuria; ... (2022). Dynamics of disease characteristics and clinical management of critically ill COVID-19 patients over the time course of the pandemic: an analysis of the prospective, international, multicentre RISC-19-ICU registry. Critical care (London, England), 26(1), p. 199. BMC 10.1186/s13054-022-04065-2

Meyhoff, Tine S; Hjortrup, Peter B; Wetterslev, Jørn; Sivapalan, Praleene; Laake, Jon H; Cronhjort, Maria; Jakob, Stephan M; Cecconi, Maurizio; Nalos, Marek; Ostermann, Marlies; Malbrain, Manu; Pettilä, Ville; Møller, Morten H; Kjær, Maj-Brit N; Lange, Theis; Overgaard-Steensen, Christian; Brand, Björn A; Winther-Olesen, Marie; White, Jonathan O; Quist, Lars; ... (2022). Restriction of Intravenous Fluid in ICU Patients with Septic Shock. The New England journal of medicine, 386(26), pp. 2459-2470. Massachusetts Medical Society 10.1056/NEJMoa2202707

Jeitziner, Marie-Madlen; Moser, André; Wendel-Garcia, Pedro D; Exl, Matthias Thomas; Keiser, Stefanie; Schuepbach, Reto A; Pietsch, Urs; Cereghetti, Sara; Boroli, Filippo; Marrel, Julien; Sigg, Anne-Aylin; Ksouri, Hatem; Schott, Peter; Dullenkopf, Alexander; Fleisch, Isabelle; Heise, Antje; Laurent, Jean-Christophe; Jakob, Stephan M; Hilty, Matthias P and Que, Yok-Ai (2022). Critical care staffing ratio and outcome of COVID-19 patients requiring intensive care unit admission during the first pandemic wave: a retrospective analysis across Switzerland from the RISC-19-ICU observational cohort. Swiss medical weekly, 152, w30183. EMH Schweizerischer Ärzteverlag 10.4414/smw.2022.w30183

Rodriguez, Belén; Branca, Mattia; Gutt-Will, Marielena; Roth, Marianne; Söll, Nicole; Nansoz, Sandra; Cameron, David R; Tankisi, Hatice; Tan, S Veronica; Bostock, Hugh; Raabe, Andreas; Schefold, Joerg C; Jakob, Stephan M; Z'Graggen, Werner J (2022). Development and early diagnosis of critical illness myopathy in COVID-19 associated acute respiratory distress syndrome. Journal of cachexia, sarcopenia and muscle, 13(3), pp. 1883-1895. Wiley 10.1002/jcsm.12989

Hays, Leanne M C; Udy, Andrew; Adamides, Alexios A; Anstey, James R; Bailey, Michael; Bellapart, Judith; Byrne, Kathleen; Cheng, Andrew; Jamie Cooper, D; Drummond, Katharine J; Haenggi, Matthias; Jakob, Stephan M; Higgins, Alisa M; Lewis, Philip M; Hunn, Martin K; McNamara, Robert; Menon, David K; Murray, Lynne; Reddi, Benjamin; Trapani, Tony; ... (2022). Effects of brain tissue oxygen (PbtO2) guided management on patient outcomes following severe traumatic brain injury: A systematic review and meta-analysis. Journal of clinical neuroscience, 99, pp. 349-358. Elsevier 10.1016/j.jocn.2022.03.017

Granholm, Anders; Kjær, Maj-Brit Nørregaard; Munch, Marie Warrer; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi E; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2022). Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia. Intensive care medicine, 48(5), pp. 580-589. Springer 10.1007/s00134-022-06677-2

Prazak, Josef; Valente, Luca; Iten, Manuela; Federer, Lea; Grandgirard, Denis; Soto, Sara; Resch, Gregory; Leib, Stephen L.; Jakob, Stephan M.; Haenggi, Matthias; Cameron, David R.; Que, Yok-Ai (2022). Benefits of aerosolized phages for the treatment of pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA): an experimental study in rats. The journal of infectious diseases, 225(8), pp. 1452-1459. Oxford University Press 10.1093/infdis/jiab112

Werner-Moller, Per; Heinisch, Paul Philipp; Hana, Anisa; Bachmann, Kaspar F; Sondergaard, Soren; Jakob, Stephan M; Takala, Jukka; Berger, David (2022). Experimental validation of a mean systemic pressure analog against zero-flow measurements in porcine VA-ECMO. Journal of applied physiology, 132(3), pp. 726-736. American Physiological Society 10.1152/japplphysiol.00804.2021

Eggmann, Sabrina; Irincheeva, Irina; Luder, Gere; Verra, Martin L.; Moser, André; Bastiaenen, Caroline H G; Jakob, Stephan M. (2022). Cardiorespiratory response to early rehabilitation in critically ill adults: A secondary analysis of a randomised controlled trial. PLoS ONE, 17(2), e0262779. Public Library of Science 10.1371/journal.pone.0262779

Moser, André; Reinikainen, Matti; Jakob, Stephan M.; Selander, Tuomas; Pettilä, Ville; Kiiski, Olli; Varpula, Tero; Raj, Rahul; Takala, Jukka (2022). Mortality prediction in intensive care units including premorbid functional status improved performance and internal validity. Journal of clinical epidemiology, 142, pp. 230-241. Elsevier 10.1016/j.jclinepi.2021.11.028

Takala, Jukka; Moser, André; Raj, Rahul; Pettilä, Ville; Irincheeva, Irina; Selander, Tuomas; Kiiski, Olli; Varpula, Tero; Reinikainen, Matti; Jakob, Stephan M. (2022). Variation in severity-adjusted resource use and outcome in intensive care units. Intensive care medicine, 48(1), pp. 67-77. Springer-Verlag 10.1007/s00134-021-06546-4

Granholm, Anders; Munch, Marie Warrer; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Kjær, Maj-Brit Nørregaard; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi E; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2022). Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial. Intensive care medicine, 48(1), pp. 45-55. Springer 10.1007/s00134-021-06573-1

Fung, Christian; Z'Graggen, Werner J.; Jakob, Stephan M.; Gralla, Jan; Haenggi, Matthias; Rothen, Hans-Ulrich; Mordasini, Pasquale; Lensch, Michael; Söll, Nicole; Terpolilli, Nicole; Feiler, Sergej; Oertel, Markus F.; Raabe, Andreas; Plesnila, Nikolaus; Takala, Jukka; Beck, Jürgen (2022). Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Delayed Cerebral Ischemia. Frontiers in neurology, 13, p. 817072. Frontiers Media S.A. 10.3389/fneur.2022.817072

Valente, Luca G; Le, Ngoc Dung; Pitton, Melissa; Chiffi, Gabriele; Grandgirard, Denis; Jakob, Stephan M; Cameron, David R; Resch, Grégory; Que, Yok-Ai; Leib, Stephen L (2022). Efficacy assessment of a novel endolysin PlyAZ3aT for the treatment of ceftriaxone-resistant pneumococcal meningitis in an infant rat model. PLoS ONE, 17(4), e0266928. Public Library of Science 10.1371/journal.pone.0266928

Naef, Aileen C; Jeitziner, Marie-Madlen; Knobel, Samuel E J; Exl, Matthias Thomas; Müri, René M; Jakob, Stephan M; Nef, Tobias; Gerber, Stephan M (2022). Investigating the role of auditory and visual sensory inputs for inducing relaxation during virtual reality stimulation. Scientific reports, 12(1), p. 17073. Springer Nature 10.1038/s41598-022-21575-9

Wolffers, Oliver; Faltys, Martin; Thomann, Janos; Jakob, Stephan M.; Marschall, Jonas; Merz, Tobias M.; Sommerstein, Rami (2021). An automated retrospective VAE-surveillance tool for future quality improvement studies. Scientific reports, 11(1), p. 22264. Springer Nature 10.1038/s41598-021-01402-3

Munch, Marie W; Myatra, Sheila N; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Saseedharan, Sanjith; Benfield, Thomas; Wahlin, Rebecka R; Rasmussen, Bodil S; Andreasen, Anne Sofie; Poulsen, Lone M; Cioccari, Luca; Khan, Mohd S; Kapadia, Farhad; Divatia, Jigeeshu V; Brøchner, Anne C; Bestle, Morten H; Helleberg, Marie; Michelsen, Jens; Padmanaban, Ajay; Bose, Neeta; Møller, Anders; ... (2021). Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial. JAMA : the journal of the American Medical Association, 326(18), pp. 1807-1817. American Medical Association 10.1001/jama.2021.18295

Munch, Marie Warrer; Meyhoff, Tine Sylvest; Helleberg, Marie; Kjaer, Maj-Brit Nørregaard; Granholm, Anders; Hjortsø, Carl Johan Steensen; Jensen, Thomas Steen; Møller, Morten Hylander; Hjortrup, Peter Buhl; Wetterslev, Mik; Vesterlund, Gitte Kingo; Russell, Lene; Jørgensen, Vibeke Lind; Kristiansen, Klaus Tjelle; Benfield, Thomas; Ulrik, Charlotte Suppli; Andreasen, Anne Sofie; Bestle, Morten Heiberg; Poulsen, Lone Musaeus; Hildebrandt, Thomas; ... (2021). Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia: The COVID STEROID randomised, placebo-controlled trial. Acta anaesthesiologica Scandinavica, 65(10), pp. 1421-1430. Wiley 10.1111/aas.13941

Cioccari, Luca; Jakob, Stephan M.; Takala, Jukka (2021). Should Vasopressors Be Started Early in Septic Shock? Seminars in respiratory and critical care medicine, 42(5), pp. 683-688. Thieme 10.1055/s-0041-1733897

Valente, Luca G.; Federer, Lea; Iten, Manuela; Grandgirard, Denis; Leib, Stephen L.; Jakob, Stephan M.; Haenggi, Matthias; Cameron, David R.; Que, Yok-Ai; Prazak, Josef (2021). Searching for synergy: combining systemic daptomycin treatment with localised phage therapy for the treatment of experimental pneumonia due to MRSA. BMC research notes, 14(1), p. 381. Biomed Central 10.1186/s13104-021-05796-1

Ferrario, Manuela; Pastorelli, Roberta; Brunelli, Laura; Liu, Shengchen; Zanella do Amaral Campos, Pedro Paulo; Casoni, Daniela; Z'Graggen, Werner J; Jakob, Stephan M (2021). Persistent hyperammonia and altered concentrations of urea cycle metabolites in a 5-day swine experiment of sepsis. Scientific reports, 11(1), p. 18430. Springer Nature 10.1038/s41598-021-97855-7

Reintam Blaser, Annika; Padar, Martin; Mändul, Merli; Elke, Gunnar; Engel, Christoph; Fischer, Krista; Giabicani, Mikhael; Gold, Thomas; Hess, Benjamin; Hiesmayr, Michael; Jakob, Stephan M.; Loudet, Cecilia I.; Meesters, Dennis M.; Mongkolpun, Wasineenart; Paugam-Burtz, Catherine; Poeze, Martijn; Preiser, Jean-Charles; Renberg, Mattias; Rooijackers, Olav; Tamme, Kadri; ... (2021). Development of the Gastrointestinal Dysfunction Score (GIDS) for critically ill patients – A prospective multicenter observational study (iSOFA study). Clinical nutrition, 40(8), pp. 4932-4940. Elsevier 10.1016/j.clnu.2021.07.015

Munch, Marie Warrer; Granholm, Anders; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Kjaer, Maj-Brit Nørregaard; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2021). Higher vs. Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: protocol and statistical analysis plan. Acta anaesthesiologica Scandinavica, 65(6), pp. 834-845. Wiley-Blackwell 10.1111/aas.13795

Jeitziner, Marie-Madlen; Jenni-Moser, Béatrice; Que, Yok-Ai; Thurnheer Zürcher, Maria Christine; Furrer, Hansjakob; Jakob, Stephan (2021). Importance of critical care staffing and standard intensive care therapy in the COVID-19 era: a descriptive study of the first epidemic wave at a Swiss tertiary intensive care unit. Swiss medical weekly, 151, w20529. EMH Media 10.4414/smw.2021.20529

Czerny, Martin; van den Berg, Jos; Chiesa, Roberto; Jacobs, Michael; Jakob, Stephan; Jenni, Hans-Jörg; Lorusso, Roberto; Pacini, Davide; Quintana, Eduardo; Rylski, Bartosz; Staier, Klaus; Tsilimparis, Nikolaos; Wyss, Thomas; Gottardi, Roman; Schmidli, Juerg (2021). Management of acute and chronic aortic disease during the COVID-19 pandemic-Results from a web-based ad hoc platform. Journal of cardiac surgery, 36(5), pp. 1683-1692. Wiley-Blackwell 10.1111/jocs.15093

Granholm, Anders; Munch, Marie Warrer; Myatra, Sheila Nainan; Vijayaraghavan, Bharath Kumar Tirupakuzhi; Cronhjort, Maria; Wahlin, Rebecka Rubenson; Jakob, Stephan M; Cioccari, Luca; Kjaer, Maj-Brit Nørregaard; Vesterlund, Gitte Kingo; Meyhoff, Tine Sylvest; Helleberg, Marie; Møller, Morten Hylander; Benfield, Thomas; Venkatesh, Balasubramanian; Hammond, Naomi; Micallef, Sharon; Bassi, Abhinav; John, Oommen; Jha, Vivekanand; ... (2021). Higher vs Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: Protocol for a secondary Bayesian analysis. Acta anaesthesiologica Scandinavica, 65(5), pp. 702-710. Wiley-Blackwell 10.1111/aas.13793

Naef, Aileen C; Jeitziner, Marie-Madlen; Gerber, Stephan M.; Jenni-Moser, Béatrice; Müri, René M.; Jakob, Stephan M.; Nef, Tobias; Hänggi, Matthias (2021). Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial. Trials, 22(1), p. 174. BioMed Central 10.1186/s13063-021-05090-2

Sakr, Yasser; François, Bruno; Solé-Violan, Jordi; Kotfis, Katarzyna; Jaschinski, Ulrich; Estella, Angel; Leone, Marc; Jakob, Stephan M.; Wittebole, Xavier; Fontes, Luis E; de Melo Gurgel, Miguel; Midega, Thais; Vincent, Jean-Louis; Ranieri, V Marco (2021). Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts. Critical care, 25(1), p. 87. BioMed Central 10.1186/s13054-020-03455-8

Reintam Blaser, Annika; Deane, Adam M; Preiser, Jean-Charles; Arabi, Yaseen M; Jakob, Stephan M. (2021). Enteral Feeding Intolerance: Updates in Definitions and Pathophysiology. Nutrition in clinical practice, 36(1), pp. 40-49. Wiley 10.1002/ncp.10599

Vankrunkelsven, Wouter; Gunst, Jan; Amrein, Karin; Bear, Danielle E; Berger, Mette M; Christopher, Kenneth B; Fuhrmann, Valentin; Hiesmayr, Michael; Ichai, Carole; Jakob, Stephan M; Lasocki, Sigismond; Montejo, Juan C; Oudemans-van Straeten, Heleen M; Preiser, Jean-Charles; Blaser, Annika Reintam; Rousseau, Anne-Françoise; Singer, Pierre; Starkopf, Joel; van Zanten, Arthur R; Weber-Carstens, Steffen; ... (2021). Monitoring and parenteral administration of micronutrients, phosphate and magnesium in critically ill patients: The VITA-TRACE survey. Clinical nutrition, 40(2), pp. 590-599. Elsevier 10.1016/j.clnu.2020.06.005

Schatlo, Bawarjan; Fung, Christian; Stienen, Martin N; Fathi, Ali R; Fandino, Javier; Smoll, Nicolas R; Zumofen, Daniel; Daniel, Roy Thomas; Burkhardt, Jan-Karl; Bervini, David; Marbacher, Serge; Reinert, Michael; D Alonzo, Donato; Ahlborn, Peter; Mendes Pereira, Vitor; Roethlisberger, Michel; Seule, Martin; Kerkeni, Hassen; Remonda, Luca; Weyerbrock, Astrid; ... (2021). Incidence and Outcome of Aneurysmal Subarachnoid Hemorrhage: The Swiss Study on Subarachnoid Hemorrhage (Swiss SOS). Stroke, 52(1), pp. 344-347. Wolters Kluwer Health 10.1161/STROKEAHA.120.029538

Berezowska, Sabina; Schmid, Andreas; Losmanová, Tereza; Trippel, Mafalda; Blank, Annika; Banz, Yara; Jakob, Stephan M.; Langer, Rupert (2021). Frequency and Significance of Pathologic Pulmonary Findings in Postmortem Examinations—A Single Center Experience before COVID-19. Diagnostics, 11(5) MDPI 10.3390/diagnostics11050894

Valente, Luca G.; Pitton, Melissa; Fürholz, Monika; Oberhaensli, Simone; Bruggmann, Rémy; Leib, Stephen L.; Jakob, Stephan M.; Resch, Grégory; Que, Yok-Ai; Cameron, David R. (2021). Isolation and characterization of bacteriophages from the human skin microbiome that infect Staphylococcus epidermidis. FEMS Microbes, 2 Oxford University Press 10.1093/femsmc/xtab003

Corrêa, Thiago Domingos; Pereira, Adriano José; Takala, Jukka; Jakob, Stephan Mathias (2020). Regional venous-arterial CO2 to arterial-venous O2 content difference ratio in experimental circulatory shock and hypoxia. Intensive care medicine experimental, 8(1), p. 64. Springer 10.1186/s40635-020-00353-9

Berger, David; Hobi, Jan; Möller, Per W.; Haenggi, Matthias; Takala, Jukka; Jakob, Stephan M. (2020). Right ventricular stroke volume assessed by pulmonary artery pulse contour analysis. Intensive care medicine experimental, 8(1), p. 58. Springer 10.1186/s40635-020-00347-7

Bräutigam, Konstantin; Hohl, Anja; Hewer, Ekkehard; Langer, Rupert; Jakob, Stephan (2020). Myeloid Sarcoma Mimicking Endocarditis: An Autopsy Case. International journal of surgical pathology, 28(7), p. 774. Sage 10.1177/1066896919900011

Petersen, Marie Warrer; Meyhoff, Tine Sylvest; Helleberg, Marie; Kjær, Maj-Brit Nørregaard; Granholm, Anders; Hjortsø, Carl Johan Steensen; Jensen, Thomas Steen; Møller, Morten Hylander; Hjortrup, Peter Buhl; Wetterslev, Mik; Vesterlund, Gitte Kingo; Russell, Lene; Jørgensen, Vibeke Lind; Tjelle, Klaus; Benfield, Thomas; Ulrik, Charlotte Suppli; Andreasen, Anne Sofie; Mohr, Thomas; Bestle, Morten H; Poulsen, Lone Musaeus; ... (2020). Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia (COVID STEROID) trial-Protocol and statistical analysis plan. Acta anaesthesiologica Scandinavica, 64(9), pp. 1365-1375. Wiley-Blackwell 10.1111/aas.13673

Liu, Shengchen; do Amaral Campos, Pedro Paulo Zanella; Casoni, Daniela; Berger, David; Kohler, Andreas; Bloch, Andreas; Bervini, David; Setzer, Florian; Cameron, David R.; Z'Graggen, Werner; Hana, Anisa; Langer, Rupert; Corrêa, Thiago D.; Beldi, Guido; Takala, Jukka; Jakob, Stephan M. (2020). Defense mechanisms to increasing back pressure for hepatic oxygen transport and venous return in porcine fecal peritonitis. American journal of physiology - gastrointestinal and liver physiology, 319(3), G289-G302. American Physiological Society 10.1152/ajpgi.00216.2020

Pfortmüller, Carmen A.; Kindler, Manuel; Schenk, Noelle; Messmer, Anna S.; Hess, Benjamin; Jakob, Laura; Wenger, Stefanie; Waskowski, Jan; Zuercher, Patrick; Stoehr, Frederik; Jakob, Stephan M.; Englberger, Lars; Schefold, Joerg C. (2020). Hypertonic saline for fluid resuscitation in ICU patients post-cardiac surgery (HERACLES): a double-blind randomized controlled clinical trial. Intensive care medicine, 46(9), pp. 1683-1695. Springer-Verlag 10.1007/s00134-020-06132-0

Cioccari, Luca; Luethi, Nora; Bailey, Michael; Shehabi, Yahya; Howe, Belinda; Messmer, Anna S.; Proimos, Helena K.; Peck, Leah; Young, Helen; Eastwood, Glenn M.; Merz, Tobias M.; Takala, Jukka; Jakob, Stephan M.; Bellomo, Rinaldo (2020). The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial. Critical care, 24(1), p. 441. BioMed Central 10.1186/s13054-020-03115-x

Egli, Adrian; Battegay, Manuel; Büchler, Andrea C; Bühlmann, Peter; Calandra, Thierry; Eckert, Philippe; Furrer, Hansjakob; Greub, Gilbert; Jakob, Stephan M.; Kaiser, Laurent; Leib, Stephen L.; Marsch, Stephan; Meinshausen, Nicolai; Pagani, Jean-Luc; Pugin, Jerome; Rätsch, Gunnar; Schrenzel, Jacques; Schüpbach, Reto; Siegemund, Martin; Zamboni, Nicola; ... (2020). SPHN/PHRT: Forming a Swiss-Wide Infrastructure for Data-Driven Sepsis Research. Studies in health technology and informatics, 270, pp. 1163-1167. IOS Press 10.3233/SHTI200346

Bachmann, Kaspar Felix; Haenggi, Matthias; Jakob, Stephan M.; Takala, Jukka; Gattinoni, Luciano; Berger, David (2020). Gas exchange calculation may estimate changes in pulmonary blood flow during veno-arterial extracorporeal membrane oxygenation in a porcine model. American journal of physiology - lung cellular and molecular physiology, 318(6), L1211-L1221. American Physiological Society 10.1152/ajplung.00167.2019

Reintam Blaser, Annika; Preiser, Jean-Charles; Fruhwald, Sonja; Wilmer, Alexander; Wernerman, Jan; Benstoem, Carina; Casaer, Michael P; Starkopf, Joel; van Zanten, Arthur; Rooyackers, Olav; Jakob, Stephan M; Loudet, Cecilia I; Bear, Danielle E; Elke, Gunnar; Kott, Matthias; Lautenschläger, Ingmar; Schäper, Jörn; Gunst, Jan; Stoppe, Christian; Nobile, Leda; ... (2020). Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine. Critical care, 24(1), p. 224. BioMed Central 10.1186/s13054-020-02889-4

Vincent, Jean-Louis; Ferguson, Andrew; Pickkers, Peter; Jakob, Stephan M.; Jaschinski, Ulrich; Almekhlafi, Ghaleb A; Leone, Marc; Mokhtari, Majid; Fontes, Luis E; Bauer, Philippe R; Sakr, Yasser (2020). The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database. Critical care, 24(1), p. 171. BioMed Central 10.1186/s13054-020-02858-x

Eggmann, Sabrina; Luder, Gere; Verra, Martin L; Irincheeva, Irina; Bastiaenen, Caroline H G; Jakob, Stephan M (2020). Functional ability and quality of life in critical illness survivors with intensive care unit acquired weakness: A secondary analysis of a randomised controlled trial. PLoS ONE, 15(3), e0229725. Public Library of Science 10.1371/journal.pone.0229725

Kjaer, Maj-Brit Nørregaard; Meyhoff, Tine Sylvest; Madsen, Martin Bruun; Hjortrup, Peter Buhl; Møller, Morten Hylander; Egerod, Ingrid; Wetterslev, Jørn; Lange, Theis; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M.; Nalos, Marek; Pettilä, Ville; van der Horst, Iwan C C; Ostermann, Marlies; Mouncey, Paul; Cecconi, Maurizio; Ferrer, Ricard; L N G Malbrain, Manu; Ahlstedt, Christian; ... (2020). Long-term patient-important outcomes after septic shock: a protocol for 1-year follow-up of the CLASSIC-trial. Acta anaesthesiologica Scandinavica, 64(3), pp. 410-416. Wiley-Blackwell 10.1111/aas.13519

Schefold, Joerg C.; Bäcklund, Minna; Ala-Kokko, Tero; Zuercher, Patrick; Mukherjee, Rajat; Mistry, Satish; Mayer, Stephan A; Dziewas, Rainer; Bakker, Jan; Jakob, Stephan M. (2020). The PhINEST study - Pharyngeal ICU Novel Electrical Stimulation Therapy: Study protocol of a prospective, multi-site, randomized, sham-controlled, single-blind (outcome assessor-blinded) study. Medicine, 99(11), e19503. Wolters Kluwer 10.1097/MD.0000000000019503

Liu, Shengchen; Moller, Per W.; Kohler, Andreas; Hana, Anisa; Beldi, Guido; Obrist, Dominik; Berger, David; Takala, Jukka; Jakob, Stephan M. (2020). Effects of Trendelenburg position and increased airway pressure on hepatic regional blood flow of normal and resected liver. Journal of applied physiology, 128(3), pp. 667-680. American Physiological Society 10.1152/japplphysiol.00705.2019

Eggmann, Sabrina; Kindler, Angela; Perren, Andrea; Ott, Natalie; Johannes, Frauke; Vollenweider, Rahel; Balma, Théophile; Bennett, Claire; Silva, Ivo Neto; Jakob, Stephan M. (2020). Early Physical Therapist Interventions for Patients With COVID-19 in the Acute Care Hospital: A Case Report Series. Physical therapy, 101(1) Oxford University Press 10.1093/ptj/pzaa194

Gerber, Stephan M.; Jeitziner, Marie-Madlen; Knobel, Samuel E. J.; Mosimann, Urs P.; Müri, René M.; Jakob, Stephan M.; Nef, Tobias (2019). Perception and Performance on a Virtual Reality Cognitive Stimulation for Use in the Intensive Care Unit: A Non-randomized Trial in Critically Ill Patients. Frontiers in medicine, 6(287), p. 287. Frontiers 10.3389/fmed.2019.00287

Prazak, Josef; Iten, Manuela; Cameron, David Robert; Save, Jonathan Florian; Grandgirard, Denis; Resch, Gregory; Göpfert, Christine; Leib, Stephen L.; Takala, Jukka; Jakob, Stephan; Que, Yok-Ai; Hänggi, Matthias (2019). Bacteriophages Improve Outcome in Experimental Staphylococcus Aureus Ventilator Associated Pneumonia. American journal of respiratory and critical care medicine, 200(9), pp. 1126-1133. American Lung Association 10.1164/rccm.201812-2372OC

Meyhoff, Tine Sylvest; Hjortrup, Peter Buhl; Møller, Morten Hylander; Wetterslev, Jørn; Lange, Theis; Kjaer, Maj-Brit Nørregaard; Jonsson, Andreas Bender; Hjortsø, Carl Johan Steensen; Cronhjort, Maria; Laake, Jon Henrik; Jakob, Stephan M.; Nalos, Marek; Pettilä, Ville; van der Horst, Iwan; Ostermann, Marlies; Mouncey, Paul; Rowan, Kathy; Cecconi, Maurizio; Ferrer, Ricard; Malbrain, Manu L N G; ... (2019). Conservative vs liberal fluid therapy in septic shock (CLASSIC) trial-Protocol and statistical analysis plan. Acta anaesthesiologica Scandinavica, 63(9), pp. 1262-1271. Wiley-Blackwell 10.1111/aas.13434

Kohler, Andreas; Moller, Per Werner; Frey, Sabrina; Tinguely, Pascale; Candinas, Daniel; Obrist, Dominik; Jakob, Stephan M.; Beldi, Guido (2019). Portal hyperperfusion after major liver resection and associated sinusoidal damage is a therapeutic target to protect the remnant liver. American journal of physiology - gastrointestinal and liver physiology, 317(3), G264-G274. American Physiological Society 10.1152/ajpgi.00113.2019

Merz, Tobias; Cioccari, Luca; Frey, Pascal Marcel; Bloch, Andreas; Berger, David; Zante, Björn; Jakob, Stephan; Takala, Jukka (2019). Correction to: Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial. Intensive care medicine, 45(9), p. 1330. Springer-Verlag 10.1007/s00134-019-05700-3

Merz, Tobias; Cioccari, Luca; Frey, Pascal Marcel; Bloch, Andreas; Berger, David; Zante, Björn; Jakob, Stephan; Takala, Jukka (2019). Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial. Intensive care medicine, 45(8), pp. 1093-1102. Springer-Verlag 10.1007/s00134-019-05670-6

Pfortmüller, Carmen; Messmer, Anna S.; Hess, Benjamin; Reineke, David; Jakob, Laura; Wenger, Stefanie; Waskowski, Jan; Zürcher, Patrick; Stöhr, Frederik; Erdös, Gabor; Luedi, Markus M.; Jakob, Stephan M.; Englberger, Lars; Schefold, Jörg C. (2019). Hypertonic saline for fluid resuscitation after cardiac surgery (HERACLES): study protocol for a preliminary randomised controlled clinical trial. Trials, 20(1), p. 357. BioMed Central 10.1186/s13063-019-3420-6

Werner Möller, Per; Sondergaard, Soren; Jakob, Stephan; Takala, Jukka; Berger, David (2019). Effect of volume status on the estimation of mean systemic filling pressure. Journal of applied physiology, 126(6), pp. 1503-1513. American Physiological Society 10.1152/japplphysiol.00897.2018

Pfortmueller, Carmen A.; Faeh, Livia; Müller, Martin; Eberle, Balthasar; Jenni, Hansjörg; Zante, Björn; Prazak, Josef; Englberger, Lars; Takala, Jukka; Jakob, Stephan M. (2019). Fluid management in patients undergoing cardiac surgery: effects of an acetate- versus lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT). Critical care, 23(1), p. 159. BioMed Central 10.1186/s13054-019-2423-8

Werner Möller, Per; Hana, Anisa; Heinisch, Paul Philipp; Liu, Shengchen; Djafarzadeh, Siamak; Hänggi, Matthias; Bloch, Andreas; Takala, Jukka; Jakob, Stephan; Berger, David (2019). The Effects of Vasoconstriction and Volume Expansion on Veno-Arterial ECMO Flow. Shock, 51(5), pp. 650-658. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001197

Bachmann, Kaspar F.; Nebiker, Mathias; Johner, Caroline; Bregy, Rachel; Schaller, André; Novak, Urban; Jakob, Stephan M. (2019). Rare Case of Transcutaneous Oxygen Desaturation in a Cancer Patient: A Case Report and Diagnostic Approach for a Recurrent Problem. A&A practice, 12(4), pp. 96-98. Lippincott Williams & Wilkins 10.1213/XAA.0000000000000855

Schefold, Joerg C.; Messmer, Anna S.; Wenger, Stefanie; Müller, Lionel; von Haehling, Stephan; Doehner, Wolfram; McPhee, Jamie S; Fux, Michaela; Rösler, Kai M; Scheidegger, Olivier; Olariu, Radu; Z'Graggen, Werner; Rezzi, Serge; Grathwohl, Dominik; Konz, Tobias; Takala, Jukka; Cuenoud, Bernard; Jakob, Stephan M. (2019). Nutrient pattern analysis in critically ill patients using Omics technology (NAChO) - Study protocol for a prospective observational study. Medicine, 98(1), e13937. Lippincott Williams & Wilkins 10.1097/MD.0000000000013937

Gerber, Stephan M; Jeitziner, Marie-Madlen; Sänger, Simon D; Knobel, Samuel E J; Marchal-Crespo, Laura; Müri, René M; Schefold, Joerg C; Jakob, Stephan M; Nef, Tobias (2019). Comparing the Relaxing Effects of Different Virtual Reality Environments in the Intensive Care Unit: Observational Study. JMIR perioperative medicine, 2(2), e15579. JMIR Publications 10.2196/15579

Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; Wise, Matt P; Schefold, Joerg C.; Keus, Frederik; Guttormsen, Anne B; Bendel, Stepani; Borthwick, Mark; Lange, Theis; Rasmussen, Bodil S; Siegemund, Martin; Bundgaard, Helle; Elkmann, Thomas; Jensen, Jacob V; Nielsen, Rune D; Liboriussen, Lisbeth; Bestle, Morten H; Elkjær, Jeanie M; ... (2018). Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU. The New England journal of medicine, 379(23), pp. 2199-2208. Massachusetts Medical Society 10.1056/NEJMoa1714919

Bloch, Andreas; Glas, Michael; Kohler, Andreas; Baumann, Ulrich; Jakob, Stephan (2018). Non-Invasive Assessment of Intra-Abdominal Pressure Using Ultrasound Guided Tonometry - a Proof-of-Concept Study. Shock, 50(6), pp. 684-688. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001085

Gorrasi, José Antonio; Jakob, Stephan; Tovar, Luis Antonio; Balsiger, Bruno Markus; Brandt, Sebastian; Brügger, Lukas; Bracht, Hendrik; Takala, Jukka (2018). Perioperative Fluid Accumulation Impairs Intestinal Contractility to a Smilar Extent as Peritonitis and Endotoxemia. Shock, 50(6), pp. 735-740. Lippincott Williams & Wilkins 10.1097/SHK.0000000000001088

Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Correction to: Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. [correction]. Trials, 19(1), p. 587. BioMed Central 10.1186/s13063-018-3001-0

Cioccari, Luca; Zante, Bjoern; Bloch, Andreas; Berger, David; Limacher, Andreas; Jakob, Stephan M; Takala, Jukka; Merz, Tobias M (2018). Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. Trials, 19(1), p. 362. BioMed Central 10.1186/s13063-018-2714-4

Perner, Anders; Cecconi, Maurizio; Cronhjort, Maria; Darmon, Michael; Jakob, Stephan; Pettilä, Ville; van der Horst, Iwan C C (2018). Expert statement for the management of hypovolemia in sepsis. Intensive care medicine, 44(6), pp. 791-798. Springer-Verlag 10.1007/s00134-018-5177-x

Boërio, Delphine; Corrêa, Thiago D; Jakob, Stephan; Ackermann, Karin A; Bostock, Hugh; Z'Graggen, Werner Josef (2018). Muscle membrane properties in A pig sepsis model: Effect of norepinephrine. Muscle & nerve, 57(5), pp. 808-813. John Wiley & Sons 10.1002/mus.26013

Vincent, Jean-Louis; Jaschinski, Ulrich; Wittebole, Xavier; Lefrant, Jean-Yves; Jakob, Stephan; Almekhlafi, Ghaleb A; Pellis, Tommaso; Tripathy, Swagata; Rubatto Birri, Paolo N; Sakr, Yasser (2018). Worldwide audit of blood transfusion practice in critically ill patients. Critical care, 22(1), p. 102. BioMed Central 10.1186/s13054-018-2018-9

Erdös, Gabor; Uehlinger, Dominik E; Kobel, Beatrice; Stucki, Monika Pia; Wiest, Roland; Stueber, Frank; Fankhauser, Niklaus; Jakob, Stephan; Schefold, Joerg C. (2018). Cerebral microembolism in the critically ill with acute kidney injury (COMET-AKI trial): study protocol for a randomized controlled clinical trial. Trials, 19(1), p. 189. BioMed Central 10.1186/s13063-018-2561-3

Bloch, Andreas; Tomaschett, Corina; Jakob, Stephan; Schwinghammer, Andreas; Schmid, Timo (2018). Compression sonography for non-invasive measurement of lower leg compartment pressure in an animal model. Injury - international journal of the care of the injured, 49(3), pp. 532-537. Elsevier 10.1016/j.injury.2017.11.036

Sommerstein, Rami; Merz, Tobias; Jakob, Stephan; Takala, Jukka; Marschall, Jonas (2018). Decontamination of Extracorporeal Membrane Oxygenator Devices With an Intensified Disinfection Protocol: How Strict Is Too Strict? Infection control and hospital epidemiology, 39(3), pp. 366-367. Cambridge University Press 10.1017/ice.2017.283

Gahl, Brigitta; Göber, Volkhard; Odutayo, Ayodele; Tevaearai Stahel, Hendrik T; Da Costa, Bruno R; Jakob, Stephan M; Fiedler, G Martin; Chan, Olivia; Carrel, Thierry P; Jüni, Peter (2018). Prognostic Value of Early Postoperative Troponin T in Patients Undergoing Coronary Artery Bypass Grafting. Journal of the American Heart Association, 7(5), e007743. American Heart Association 10.1161/JAHA.117.007743

Glas, Michael; Frick, Tamara; Springe, Dirk; Putzu, Alessandro; Zürcher, Patrick; Grandgirard, Denis; Leib, Stephen; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2018). Neuroprotection with the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model. Shock, 49(2), pp. 229-234. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000917

Eggmann, Sabrina; Verra, Martin L.; Luder, Gere; Takala, Jukka; Jakob, Stephan (2018). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: A randomised controlled trial. PLoS ONE, 13(11), e0207428. Public Library of Science 10.1371/journal.pone.0207428

Schefold, Joerg C.; Berger, David; Zürcher, Patrick; Lensch, Michael; Perren, Andrea; Jakob, Stephan; Parviainen, Ilkka; Takala, Jukka (2017). Dysphagia in Mechanically Ventilated ICU Patients (DYnAMICS): A Prospective Observational Trial. Critical care medicine, 45(12), pp. 2061-2069. Lippincott Williams & Wilkins 10.1097/CCM.0000000000002765

Jakob, Stephan; Takala, Jukka (2017). Subcellular Energetics and Metabolism: A Cross-Species Framework. Anesthesia and analgesia, 125(6), p. 2160. Lippincott Williams & Wilkins 10.1213/ANE.0000000000002476

Bauer, Philippe R; Gajic, Ognjen; Nanchal, Rahul; Kashyap, Rahul; Martin-Loeches, Ignacio; Sakr, Yasser; Jakob, Stephan; François, Bruno; Wittebole, Xavier; Wunderink, Richard G; Vincent, Jean-Louis (2017). Association between timing of intubation and outcome in critically ill patients: A secondary analysis of the ICON audit. Journal of critical care, 42, pp. 1-5. Elsevier 10.1016/j.jcrc.2017.06.010

Gerber, Stephan Moreno; Jeitziner, Marie-Madlen; Wyss, Patric; Chesham, Alvin; Urwyler, Prabitha; Müri, René Martin; Jakob, Stephan; Nef, Tobias (2017). Visuo-acoustic stimulation that helps you to relax: A virtual reality setup for patients in the intensive care unit. Scientific Reports, 7(1), pp. 1-10. Nature Publishing Group 10.1038/s41598-017-13153-1

Werner Möller, Per; Winkler, Berhard; Hurni, Samuel; Heinisch, Paul Philipp; Bloch, Andreas; Sondergaard, Soren; Jakob, Stephan; Takala, Jukka; Berger, David (2017). Right atrial pressure and venous return during cardiopulmonary bypass. American journal of physiology - heart and circulatory physiology, 313(2), H408-H420. American Physiological Society 10.1152/ajpheart.00081.2017

Bloch, Andreas; Kohler, Andreas; Posthaus, Horst; Berger, David; Santos, Laura; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2017). Gastrointestinal Impedance Spectroscopy to Detect Hypoperfusion During Hemorrhage. Shock, 48(2), pp. 185-195. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000824

Lobo, Suzana M; De Simoni, Flávio H B; Jakob, Stephan; Estella, Angel; Vadi, Sonali; Bluethgen, Andreas; Martin-Loeches, Ignacio; Sakr, Yasser; Vincent, Jean-Louis (2017). Decision-Making on Withholding or Withdrawing Life Support in the ICU: A Worldwide Perspective. Chest, 152(2), pp. 321-329. American College of Chest Physicians 10.1016/j.chest.2017.04.176

Jakob, Stephan M; Bütikofer, Lukas; Berger, David; Coslovsky, Michael; Takala, Jukka (2017). A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient-the SPIRIT trial. Critical care, 21(1), p. 140. BioMed Central 10.1186/s13054-017-1730-1

De Marchis, Gian Marco; Schaad, Chris; Fung, Christian; Beck, Jürgen; Gralla, Jan; Takala, Jukka; Jakob, Stephan (2017). Gender-related differences in aneurysmal subarachnoid hemorrhage: A hospital based study. Clinical neurology and neurosurgery, 157, pp. 82-87. Elsevier 10.1016/j.clineuro.2017.04.009

Corrêa, Thiago Domingos; Pereira, Adriano José; Brandt, Sebastian; Vuda, Madhusudanarao; Djafarzadeh, Siamak; Takala, Jukka; Jakob, Stephan (2017). Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Critical care, 21(1), p. 105. BioMed Central 10.1186/s13054-017-1691-4

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Jakob, Stephan; Takala, Jukka (2017). Comments on Teboul and Scheeren: understanding the Haldane effect. Intensive care medicine, 43(4), p. 597. Springer 10.1007/s00134-017-4697-0

Berger, David; Werner Möller, Per; Blöchlinger, Stefan; Bloch, Andreas; Jakob, Stephan; Takala, Jukka (21 March 2017). P106 Methodological issues for the determination of mean systemic filling pressure at the end of life. Critical care, 21(Suppl1), p. 41. BioMed Central

Werner Möller, Per; Jakob, Stephan; Takala, Jukka; Berger, David (21 March 2017). P108 Right atrial pressure as back-pressure to venous return. Critical care, 21(Suppl 1), pp. 41-42. BioMed Central

Djafarzadeh, Siamak; Jakob, Stephan (2017). Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements. Journal of visualized experiments(121) MYJoVE Corporation 10.3791/55251

Djafarzadeh, Siamak; Jakob, Stephan (2017). High-resolution Respirometry to Assess Mitochondrial Function in Permeabilized and Intact Cells. Journal of visualized experiments(120) MYJoVE Corporation 10.3791/54985

Varis, Elina; Pettilä, Ville Yrjö Olavi; Poukkanen, Meri; Jakob, Stephan; Karlsson, Sari; Perner, Anders; Takala, Jukka; Wilkman, Erika (2017). Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the Finnaki Study. Shock, 47(5), pp. 574-581. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000772

Reintam Blaser, Annika; Starkopf, Joel; Alhazzani, Waleed; Berger, Mette M.; Casaer, Michael P.; Deane, Adam M.; Fruhwald, Sonja; Hiesmayr, Michael; Ichai, Carole; Jakob, Stephan; Loudet, Cecilia I.; Malbrain, Manu L. N. G.; Montejo González, Juan C.; Paugam-Burtz, Catherine; Poeze, Martijn; Preiser, Jean-Charles; Singer, Pierre; van Zanten, Arthur R.H.; De Waele, Jan; Wendon, Julia; ... (2017). Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines. Intensive care medicine, 43(3), pp. 380-398. Springer 10.1007/s00134-016-4665-0

Merz, Tobias; Pereira, Adriano J; Schürch, Roger; Schefold, Joerg C.; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2017). Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. PLoS ONE, 12(6), e0178946. Public Library of Science 10.1371/journal.pone.0178946

Kessler, Ulf; Schlapbach, Luregn J.; Klimek, Peter Michael; Jakob, Stephan (2017). Low L-Ficolin associated with disease severity during sepsis in adult ICU patients. Liver international, 37(9), p. 1409. Blackwell Munksgaard 10.1111/liv.13448

Nobile, Leda; Taccone, Fabio S; Szakmany, Tamas; Sakr, Yasser; Jakob, Stephan; Pellis, Tommaso; Antonelli, Massimo; Leone, Marc; Wittebole, Xavier; Pickkers, Peter; Vincent, Jean-Louis (2016). The impact of extracerebral organ failure on outcome of patients after cardiac arrest: an observational study from the ICON database. Critical care, 20(1), p. 368. BioMed Central 10.1186/s13054-016-1528-6

Bhaskar, Monica; Jakob, Stephan; Djafarzadeh, Siamak (2 November 2016). Effect of cytomix and sedative drugs on mitochondrial electron transport chain of cultured primary human astrocytes (Unpublished). In: Day of Clinical Research 2016.

Pettilä, Ville Yrjö Olavi; Jakob, Stephan; Takala, Jukka (2016). The new sepsis/septic shock-3 definition is just not enough - more detailed research is needed. Acta anaesthesiologica Scandinavica, 60(10), pp. 1344-1346. Wiley-Blackwell 10.1111/aas.12777

Martin-Loeches, Ignacio; Wunderink, Richard G; Nanchal, Rahul; Lefrant, Jean Yves; Kapadia, Farhad; Sakr, Yasser; Vincent, Jean-Louis; Jakob, Stephan (2016). Determinants of time to death in hospital in critically ill patients around the world. Intensive care medicine, 42(9), pp. 1454-1460. Springer 10.1007/s00134-016-4479-0

Eggmann, Sabrina; Verra, Martin L; Luder, Gere; Takala, Jukka; Jakob, Stephan (2016). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: a study protocol for a randomised controlled trial. Trials, 17, p. 403. BioMed Central 10.1186/s13063-016-1533-8

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Jeger, Victor; Takala, Jukka; Jakob, Stephan (2016). The Effects of Fentanyl on Hepatic Mitochondrial Function. Anesthesia and analgesia, 123(2), pp. 311-325. International Anesthesia Research Society 10.1213/ANE.0000000000001280

Pettilä, Ville Yrjö Olavi; Hjortrup, Peter Buhl; Jakob, Stephan; Wilkman, Erika; Perner, Anders; Takala, Jukka (2016). Control groups in recent septic shock trials: a systematic review. Intensive care medicine, 42(12), pp. 1912-1921. Springer 10.1007/s00134-016-4444-y

Berger, David; Werner Möller, Per; Weber, Alberto; Bloch, Andreas; Bloechlinger, Stefan; Hänggi, Matthias; Sondergaard, Soren; Jakob, Stephan; Magder, Sheldon; Takala, Jukka (2016). Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. American journal of physiology - heart and circulatory physiology, 311(3), H794-H806. American Physiological Society 10.1152/ajpheart.00931.2015

Möller, P. W.; Jakob, Stephan M.; Takala, Jukka; Berger, David; Stanga, Zeno (2016). 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016. Critical care (London, England), 20(Suppl 2), p. 94. 10.1186/s13054-016-1208-6

Takala, Jukka; Jakob, Stephan (2016). Oxygen transport in the critically ill. In: Webb, Andrew; Angus, Derek; Finfer, Simon; Gattinoni, Luciano; Singer, Mervyn (eds.) Oxford Textbook of Critical Care (pp. 636-639). Oxford University Press

Reintam Blaser, Annika; Jakob, Stephan; Starkopf, Joel (2016). Gastrointestinal failure in the ICU. Current opinion in critical care, 22(2), pp. 128-141. Lippincott Williams & Wilkins 10.1097/MCC.0000000000000286

Basciani, Reto Marco; Rindlisbacher, Antje; Begert, Esther; Brander, Luc; Jakob, Stephan; Etter, Reto; Carrel, Thierry; Eberle, Balthasar (2016). Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial. European journal of anaesthesiology, 33(6), pp. 417-424. Lippincott Williams & Wilkins 10.1097/EJA.0000000000000434

Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8

Pettilä, Ville Yrjö Olavi; Merz, Tobias Michael; Wilkman, Erika; Perner, Anders; Karlsson, Sari; Lange, Theis; Hästbacka, Johanna; Hjortrup, Peter Buhl; Kuitunen, Anne; Jakob, Stephan; Takala, Jukka (2016). Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial. Trials, 17(384), p. 384. BioMed Central 10.1186/s13063-016-1515-x

Zubler, Frederic; Koenig, Christa; Steimer, Andreas; Jakob, Stephan; Schindler, Kaspar Anton; Gast, Heidemarie (2015). Prognostic and diagnostic value of EEG signal coupling measures in coma. Clinical neurophysiology, 127(8), pp. 2942-2952. Elsevier 10.1016/j.clinph.2015.08.022

Fung, Christian; Inglin, Fabienne; Murek, Michael Konrad; Balmer, Mathias; Abu-Isa, Janine; Z'Graggen, Werner Josef; Ozdoba, Christoph; Gralla, Jan; Jakob, Stephan; Takala, Jukka; Beck, Jürgen; Raabe, Andreas (2015). Reconsidering the logic of World Federation of Neurosurgical Societies grading in patients with severe subarachnoid hemorrhage. Journal of neurosurgery, 124(2), pp. 299-304. American Association of Neurological Surgeons 10.3171/2015.2.JNS14614

Merz, Tobias Michael; Pichler Hefti, Jacqueline Renée; Hefti, Urs; Huber, Andreas; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Changes in mitochondrial enzymatic activities of monocytes during prolonged hypobaric hypoxia and influence of antioxidants: A randomized controlled study. Redox report, 20(5), pp. 234-240. Maney Publishing 10.1179/1351000215Y.0000000007

Bloechlinger, Stefan; Berger, David; Bryner, Jürg; Roost, Eva; Jakob, Stephan; Dünser, Martin W; Takala, Jukka (2015). Changes in Left Ventricular Torsion Early Postoperatively After Aortic Valve Replacement and at Long-Term Follow-up. Journal of cardiothoracic and vascular anesthesia, 29(4), pp. 860-867. Elsevier 10.1053/j.jvca.2015.01.010

Jakob, Stephan; Groeneveld, A B Johan; Teboul, Jean-Louis (2015). Venous-arterial CO2 to arterial-venous O2 difference ratio as a resuscitation target in shock states? Intensive care medicine, 41(5), pp. 936-938. Springer 10.1007/s00134-015-3778-1

Bänziger, B; Regueira, T; Vogt, R; Brandt, S; Vandevelde, M; Jakob, Stephan (2015). Neurohistological abnormalities during early porcine endotoxemia. Acta anaesthesiologica Scandinavica, 59(5), pp. 586-597. Wiley-Blackwell 10.1111/aas.12512

Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC anesthesiology, 15(2), p. 2. BioMed Central 10.1186/1471-2253-15-2

Fung, Christian; Balmer, Mathias; Murek, Michael; Z'Graggen, Werner Josef; Abu-Isa, Janine; Ozdoba, Christoph; Hänggi, Matthias; Jakob, Stephan; Raabe, Andreas; Beck, Jürgen (2015). Impact of early-onset seizures on grading and outcome in patients with subarachnoid hemorrhage. Journal of neurosurgery, 122(2), pp. 408-413. American Association of Neurological Surgeons 10.3171/2014.10.JNS14163

Marbacher, Serge; Fathi, Ali Reza; Muroi, Carl; Coluccia, Daniel; Andereggen, Lukas; Neuschmelting, Volker; Widmer, Hans Rudolf; Jakob, Stephan M.; Fandino, Javier (2015). The rabbit blood shunt subarachnoid haemorrhage model. Acta neurochirurgica - supplementa, 120, pp. 337-342. Springer 10.1007/978-3-319-04981-6_58

Ackermann, Karin; Brander, Lukas; Tuchscherer, Daniel; Schröder, Ralph; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2015). Esophageal versus surface recording of diaphragm compound muscle action potential. Muscle & nerve, 51(4), pp. 598-600. John Wiley & Sons 10.1002/mus.24577

Corrêa, Thiago Domingos; Takala, Jukka; Jakob, Stephan (2015). Is lactate clearance impaired in septic shock? Critical care, 19(306), p. 306. BioMed Central 10.1186/s13054-015-1039-x

Corrêa, Thiago Domingos; Jakob, Stephan; Takala, Jukka (2015). Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? Critical care, 19(264), p. 264. BioMed Central 10.1186/s13054-015-0958-x

Turunen, Heidi; Jakob, Stephan; Ruokonen, Esko; Kaukonen, Kirsi-Maija; Sarapohja, Toni; Apajasalo, Marjo; Takala, Jukka (2015). Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation. Critical care, 19(67), p. 67. BioMed Central 10.1186/s13054-015-0787-y

Corrêa, Thiago D; Takala, Jukka; Jakob, Stephan (2015). Angiotensin II in septic shock. Critical care, 19(98), p. 98. BioMed Central 10.1186/s13054-015-0802-3

Jeger, Victor; Brandt, Sebastian; Porta, Francesca; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Dose response of endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed research international, 2015, p. 353074. Hindawi Publishing Corporation 10.1155/2015/353074

Marbacher, Serge; Nevzati, Edin; Croci, Davide; Erhardt, Salome; Muroi, Carl; Jakob, Stephan; Fandino, Javier (2014). The Rabbit Shunt Model of Subarachnoid Haemorrhage. Translational stroke research, 5(6), pp. 669-680. Springer 10.1007/s12975-014-0369-3

Marbacher, Serge; Neuschmelting, Volker; Andereggen, Lukas; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2014). Early brain injury linearly correlates with reduction in cerebral perfusion pressure during the hyperacute phase of subarachnoid hemorrhage. Intensive care medicine experimental, 2(1), p. 30. Springer 10.1186/s40635-014-0030-1

Andereggen, Lukas; Neuschmelting, Volker; von Gunten, Michael; Widmer, Hans Rudolf; Takala, Jukka; Jakob, Stephan; Fandino, Javier; Marbacher, Serge (2014). The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects. Journal of visualized experiments(92), e52132. MYJoVE Corporation 10.3791/52132

Hänggi, Matthias; Jakob, Stephan; Takala, Jukka (2014). Sedation level and prevalence of delirium: response to Brummel and Ely. Intensive care medicine, 40(1), p. 136. Springer 10.1007/s00134-013-3092-8

Pereira, A. J.; Jeger, V.; Fahrner, R.; Djafarzadeh, Siamak; Lensch, Michael; Takala, Jukka; Jakob, Stephan (2014). Interference of angiotensin II and enalapril with hepatic blood flow regulation. American journal of physiology - gastrointestinal and liver physiology, 307(6), G655-G663. American Physiological Society 10.1152/ajpgi.00150.2014

Corrêa, Thiago D.; Jeger, Victor; Pereira, Adriano José; Takala, Jukka; Djafarzadeh, Siamak; Jakob, Stephan (2014). Angiotensin II in Septic Shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Critical care medicine, 42(8), e550-e559. Lippincott Williams & Wilkins 10.1097/CCM.0000000000000397

Ackermann, Karin; Bostock, Hugh; Brander, Lukas; Schröder, Ralph; Djafarzadeh, Siamak; Tuchscherer, Daniel; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2014). Early changes of muscle membrane properties in porcine faecal peritonitis. Critical care, 18(4), p. 484. BioMed Central 10.1186/s13054-014-0484-2

Jakob, Stephan; Ruokonen, E.; Takala, Jukka (2014). Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients. British journal of anaesthesia, 112(3), pp. 581-582. Oxford University Press 10.1093/bja/aeu032

Gorrasi, José; Eleftheriadis, Anestis; Takala, Jukka; Brandt, Sebastian; Djafarzadeh, Siamak; Brügger, Lukas; Bracht, Hendrik; Jakob, Stephan (2013). Different Contribution of Splanchnic Organs to Hyperlactatemia in Fecal Peritonitis and Cardiac Tamponade. BioMed research international, 2013, pp. 1-8. Hindawi Publishing Corporation 10.1155/2013/251084

Astin, Ronan; Bentham, Robert; Djafarzadeh, Siamak; Horscroft, James A.; Kuc, Rhoda E.; Leung, Po Sing; Skipworth, James R. A.; Vicencio, Jose M.; Davenport, Anthony P.; Murray, Andrew J.; Takala, Jukka; Jakob, Stephan; Montgomery, Hugh; Szabadkai, Gyorgy (2013). No evidence for a local renin-angiotensin system in liver mitochondria. Scientific Reports, 3(1), p. 2467. Nature Publishing Group 10.1038/srep02467

Corrêa, Thiago Domingos; Takala, Jukka; Jakob, Stephan (2013). Target blood pressure in sepsis: between a rock and a hard place. Critical care, 17(3), p. 433. BioMed Central 10.1186/cc12692

Jeger, Victor; Djafarzadeh, Siamak; Jakob, Stephan; Takala, Jukka (2013). Mitochondrial function in sepsis. European journal of clinical investigation, 43(5), pp. 532-542. Wiley-Blackwell 10.1111/eci.12069

Corrêa, Thiago Domingos; Vuda, Madhusudanarao; Takala, Jukka; Djafarzadeh, Siamak; Silva, Eliézer; Jakob, Stephan (2013). Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Critical care, 17(1), R21. BioMed Central 10.1186/cc12495

Lehmann, Laura; Bendel, Stepani; Uehlinger, Dominik E; Takala, Jukka; Schafer, Margaret; Reinert, Michael; Jakob, Stephan M (2013). Randomized, Double-Blind Trial of the Effect of Fluid Composition on Electrolyte, Acid-Base, and Fluid Homeostasis in Patients Early After Subarachnoid Hemorrhage. Neurocritical care, 18(1), pp. 5-12. New York, N.Y.: Springer 10.1007/s12028-012-9764-3

Torgersen, Christian-Erik; Meichtry, Jurka; Schmittinger, Christian A; Blöchlinger, Stefan; Jakob, Stephan M; Takala, Jukka; Dünser, Martin Wolfgang (2013). Haemodynamic variables and functional outcome in hypothermic patients following out-of-hospital cardiac arrest. Resuscitation, 84(6), pp. 798-804. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2012.10.012

Hänggi, Matthias; Blum, Sina; Brechbuehl, Ruth; Brunello, Anna; Jakob, Stephan; Takala, Jukka (2013). Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC. Intensive care medicine, 39(12), pp. 2171-2179. Springer Berlin Heidelberg 10.1007/s00134-013-3034-5

Fung, Christian; Z'graggen, Werner J; Beck, Jürgen; Gralla, Jan; Jakob, Stephan M; Schucht, Philippe; Raabe, Andreas (2012). Traumatic subarachnoid hemorrhage, basal ganglia hematoma and ischemic stroke caused by a torn lenticulostriate artery. Acta neurochirurgica, 154(1), pp. 59-62. Wien: Springer Vienna 10.1007/s00701-011-1162-7

Jakob, Stephan M; Ruokonen, Esko; Grounds, R Michael; Sarapohja, Toni; Garratt, Chris; Pocock, Stuart J; Bratty, J Raymond; Takala, Jukka; Dexmedetomidine for Long-Term Sedation, Investigators (2012). Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA - the journal of the American Medical Association, 307(11), pp. 1151-60. Chicago, Ill.: American Medical Association 10.1001/jama.2012.304

Reintam Blaser, Annika; Malbrain, Manu L N G; Starkopf, Joel; Fruhwald, Sonja; Jakob, Stephan M; De Waele, Jan; Braun, Jan-Peter; Poeze, Martijn; Spies, Claudia (2012). Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems. Intensive care medicine, 38(3), pp. 384-94. Berlin: Springer-Verlag 10.1007/s00134-011-2459-y

Marbacher, Serge; Andereggen, Lukas; Neuschmelting, Volker; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2012). A new rabbit model for the study of early brain injury after subarachnoid hemorrhage. Journal of neuroscience methods, 208(2), pp. 138-145. Amsterdam: Elsevier 10.1016/j.jneumeth.2012.05.010

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M (2012). Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS ONE, 7(9), e45195. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0045195

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2011). Preliminary results of an ICP-controlled subarachnoid hemorrhage rabbit model for the study of delayed cerebral vasospasm. Acta neurochirurgica - supplementa, 110(Pt 1), pp. 163-5. Wien: Springer 10.1007/978-3-7091-0353-1_28

Fathi, Ali Reza; Marbacher, Serge; Graupner, Thilo; Wehrli, Felix; Jakob, Stephan M; Schroth, Gerhard; Fandino, Javier (2011). Continuous intrathecal glyceryl trinitrate prevents delayed cerebral vasospasm in the single-SAH rabbit model in vivo. Acta neurochirurgica, 153(8), pp. 1669-1675. Wien: Springer Vienna 10.1007/s00701-011-1049-7

Takala, Jukka; Ruokonen, Esko; Tenhunen, Jyrki J; Parviainen, Ilkka; Jakob, Stephan M (2011). Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial. Critical care, 15(3), R148. London: BioMed Central 10.1186/cc10273

Shafighi, Maziar; Olariu, Radu; Fathi, Ali R; Djafarzadeh, Siamak; Jakob, Stephan M; Banic, Andrej; Constantinescu, Mihai A (2011). Dimethyloxalylglycine stabilizes HIF-1α in cultured human endothelial cells and increases random-pattern skin flap survival in vivo. Plastic and reconstructive surgery, 128(2), pp. 415-422. Lippincott Williams & Wilkins 10.1097/PRS.0b013e31821e6e69

Brunello, Anna-Giulia; Haenggi, Matthias; Wigger, Oliver; Porta, Francesca; Takala, Jukka; Jakob, Stephan M (2010). Usefulness of a clinical diagnosis of ICU-acquired paresis to predict outcome in patients with SIRS and acute respiratory failure. Intensive care medicine, 36(1), pp. 66-74. Berlin: Springer-Verlag 10.1007/s00134-009-1645-7

Spirig, Rolf; Djafarzadeh, Siamak; Regueira, Tomas; Shaw, Sidney G; von Garnier, Christophe; Takala, Jukka; Jakob, Stephan M; Rieben, Robert; Lepper, Philipp M (2010). Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions. PLoS ONE, 5(6), e0010983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0010983

Jakob, Stephan M; Stanga, Zeno (2010). Perioperative metabolic changes in patients undergoing cardiac surgery. Nutrition, 26(4), pp. 349-53. New York, N.Y.: Elsevier 10.1016/j.nut.2009.07.014

Barthelmes, D; Jakob, S M; Laitinen, S; Rahikainen, S; Ahonen, H; Takala, J (2010). Effect of site of lactate infusion on regional lactate exchange in pigs. British journal of anaesthesia, 105(5), pp. 627-34. Oxford: Oxford University Press 10.1093/bja/aeq214

Wyler von Ballmoos, Moritz; Takala, Jukka; Roeck, Margareta; Porta, Francesca; Tueller, David; Ganter, Christoph C; Schröder, Ralph; Bracht, Hendrik; Baenziger, Bertram; Jakob, Stephan M (2010). Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study. Critical care, 14(3), R111. London: BioMed Central 10.1186/cc9060

Dahlqvist, Mats B; Andres, Robert H; Raabe, Andreas; Jakob, Stephan M; Takala, Jukka; Dünser, Martin W (2010). Brain herniation in a patient with apparently normal intracranial pressure: a case report. Journal of medical case reports, 4, p. 297. London: BioMed Central

Daudel, Fritz; Tüller, David; Krähenbühl, Stefanie; Jakob, Stephan M; Takala, Jukka (2010). Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study. Critical care, 14(3), R122. London: BioMed Central 10.1186/cc9080

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2010). Extra-intracranial blood shunt mimicking aneurysm rupture: intracranial-pressure-controlled rabbit subarachnoid hemorrhage model. Journal of neuroscience methods, 191(2), pp. 227-33. Amsterdam: Elsevier 10.1016/j.jneumeth.2010.07.004

Jakob, Stephan M; Knuesel, Rafael; Tenhunen, Jyrki J; Pradl, Richard; Takala, Jukka (2010). Increasing abdominal pressure with and without PEEP: effects on intra-peritoneal, intra-organ and intra-vascular pressures. BMC gastroenterology, 10, p. 70. London: BioMed Central 10.1186/1471-230X-10-70

Jeger, Victor; Jakob, Stephan M; Fontana, Stefano; Wolf, Martin; Zimmermann, Heinz; Exadaktylos, Aristomenis K (2010). 500 ml of blood loss does not decrease non-invasive tissue oxygen saturation (StO2) as measured by near infrared spectroscopy - A hypothesis generating pilot study in healthy adult women. Journal of trauma management & outcomes, 4, p. 5. London: BioMed Central 10.1186/1752-2897-4-5

Brügger, Lukas E; Beldi, Guido; Beck, Mario; Porta, Francesca; Bracht, Hendrik; Candinas, Daniel; Takala, Jukka; Jakob, Stephan M (2010). Splanchnic vasoregulation after major abdominal surgery in pigs. World journal of surgery, 34(9), pp. 2057-63. New York, N.Y.: Springer

Ruokonen, Esko; Parviainen, Ilkka; Jakob, Stephan M; Nunes, Silvia; Kaukonen, Maija; Shepherd, Stephen T; Sarapohja, Toni; Bratty, J Raymond; Takala, Jukka (2009). Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. Intensive care medicine, 35(2), pp. 282-90. Berlin: Springer-Verlag 10.1007/s00134-008-1296-0

Neuschmelting, Volker; Fathi, Ali-Reza; Hidalgo Staub, Eveline Teresa; Marbacher, Serge; Schroth, Gerhard; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2009). Norepinephrine-induced hypertension dilates vasospastic basilar artery after subarachnoid haemorrhage in rabbits. Acta neurochirurgica, 151(5), pp. 487-93. Wien: Springer Vienna 10.1007/s00701-009-0287-4

Neuschmelting, Volker; Marbacher, Serge; Fathi, Ali-Reza; Jakob, Stephan M; Fandino, Javier (2009). Elevated level of endothelin-1 in cerebrospinal fluid and lack of nitric oxide in basilar arterial plasma associated with cerebral vasospasm after subarachnoid haemorrhage in rabbits. Acta neurochirurgica, 151(7), 795-801; discussion 801. Wien: Springer Vienna 10.1007/s00701-009-0350-1

Daudel, Fritz; Kessler, Ulf; Folly, Hélène; Lienert, Jasmin S; Takala, Jukka; Jakob, Stephan M (2009). Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study. Critical care, 13(2), R42. London: BioMed Central 10.1186/cc7765

Dünser, Martin W; Takala, Jukka; Ulmer, Hanno; Mayr, Viktoria D; Luckner, Günter; Jochberger, Stefan; Daudel, Fritz; Lepper, Philipp; Hasibeder, Walter R; Jakob, Stephan M (2009). Arterial blood pressure during early sepsis and outcome. Intensive care medicine, 35(7), pp. 1225-33. Berlin: Springer-Verlag 10.1007/s00134-009-1427-2

Dünser, Martin W; Ruokonen, Esko; Pettilä, Ville; Ulmer, Hanno; Torgersen, Christian; Schmittinger, Christian A; Jakob, Stephan; Takala, Jukka (2009). Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Critical care, 13(6), R181. London: BioMed Central 10.1186/cc8167

Haenggi, Matthias; Ypparila-Wolters, Heidi; Hauser, Kathrin; Caviezel, Claudio; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2009). Intra- and inter-individual variation of BIS-index and Entropy during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventional study. Critical care, 13(1), R20. London: BioMed Central 10.1186/cc7723

Torgersen, Christian; Schmittinger, Christian A; Wagner, Sarah; Ulmer, Hanno; Takala, Jukka; Jakob, Stephan M; Dünser, Martin W (2009). Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study. Critical care, 13(5), R157. London: BioMed Central 10.1186/cc8114

Farese, Stefan; Jakob, Stephan M; Kalicki, Robert; Frey, Felix J; Uehlinger, Dominik E (2009). Treatment of acute renal failure in the intensive care unit: lower costs by intermittent dialysis than continuous venovenous hemodiafiltration. Artificial organs, 33(8), pp. 634-40. Malden, Mass.: Wiley-Blackwell 10.1111/j.1525-1594.2009.00794.x

Jakob, Stephan (2009). Septic shock resuscitation: what goals and how to achieve them? Critical care, 13(3), p. 147. London: BioMed Central 10.1186/cc7870

Takala, Jukka; Jakob, Stephan M (2009). Shedding light on microcirculation? Intensive care medicine, 35(3), pp. 394-6. Berlin: Springer-Verlag 10.1007/s00134-008-1386-z

Porta, Francesca; Bracht, Hendrik; Weikert, Christian; Beck, Mario; Takala, Jukka; Brandt, Sebastian; Hiltebrand, Luzius B; Jakob, Stephan M (2009). Effects of endotoxin and catecholamines on hepatic mitochondrial respiration. Inflammation, 32(5), pp. 315-21. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10753-009-9138-y

Bracht, Hendrik; Krejci, Vladimir; Hiltebrand, Luzius; Brandt, Sebastian; Sigurdsson, Gisli; Ali, Syed Z; Takala, Jukka; Jakob, Stephan M (2008). Orthogonal polarization spectroscopy to detect mesenteric hypoperfusion. Intensive care medicine, 34(10), pp. 1883-90. Berlin: Springer-Verlag 10.1007/s00134-008-1130-8

Regueira, Tomas; Bänziger, Bertram; Djafarzadeh, Siamak; Brandt, Sebastian; Gorrasi, Jose; Takala, Jukka; Lepper, Philipp M; Jakob, Stephan M (2008). Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Critical care, 12(4), R88. London: BioMed Central 10.1186/cc6956

Marbacher, Serge; Neuschmelting, Volker; Graupner, Thilo; Jakob, Stephan M; Fandino, Javier (2008). Prevention of delayed cerebral vasospasm by continuous intrathecal infusion of glyceroltrinitrate and nimodipine in the rabbit model in vivo. Intensive care medicine, 34(5), pp. 932-8. Berlin: Springer-Verlag 10.1007/s00134-008-0995-x

Jakob, Stephan (2008). It makes a difference! Wiener klinische Wochenschrift, 120(19-20), pp. 581-2. Wien: Springer Vienna 10.1007/s00508-008-1082-6

Hänggi, Matthias; Ypparila-Wolters, Heidi; Bieri, Christine; Steiner, Carola; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2008). Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study. Critical care, 12(5), R119. London: BioMed Central 10.1186/cc7015

Takala, Jukka; Dellinger, R Philip; Koskinen, Kati; St Andre, Arthur; Read, Martyn; Levy, Mitchell; Jakob, Stephan M; Mello, Patricia Veiga C; Friolet, Raymond; Ruokonen, Esko (2008). Development and simultaneous application of multiple care protocols in critical care: a multicenter feasibility study. Intensive care medicine, 34(8), pp. 1401-10. Berlin: Springer-Verlag 10.1007/s00134-008-1084-x

Bracht, Hendrik; Hänggi, Matthias; Jeker, Barbara; Wegmüller, Ninja; Porta, Francesca; Tüller, David; Takala, Jukka; Jakob, Stephan M (2007). Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study. Critical care, 11(1), R2. London: BioMed Central 10.1186/cc5144

Porta, Francesca; Takala, Jukka; Weikert, Christian; Bracht, Hendrik; Kolarova, Anna; Lauterburg, Bernhard H; Borotto, Erika; Jakob, Stephan M (2006). Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function. Critical care, 10(4), R118. London: BioMed Central 10.1186/cc5013

Luginbühl, M; Rüfenacht, M; Korhonen, I; Gils, M; Jakob, S; Petersen-Felix, S. (2006). Stimulation induced variability of pulse plethysmography does not discriminate responsiveness to intubation. British journal of anaesthesia, 96(3), pp. 323-329. Oxford: Oxford University Press 10.1093/bja/aei315

Collaborative Study Group on Perioperative ScvO2 Monitoring (KIM, H; Haenggi, M; Jakob, SM; Loher, S; Raeber, C; Takala, J) (2006). Multicentre study on peri- and postoperative central venous oxygen saturation in high-risk surgical patients. Critical care, 10(6), R158. London: BioMed Central 10.1186/cc5094

Uehlinger, Dominik E; Jakob, Stephan M; Ferrari, Paolo; Eichelberger, Markus; Huynh-Do, Uyen; Marti, Hans-Peter; Mohaupt, Markus G; Vogt, Bruno; Rothen, Hans Ulrich; Regli, Bruno; Takala, Jukka; Frey, Felix J (2005). Comparison of continuous and intermittent renal replacement therapy for acute renal failure. Nephrology, dialysis, transplantation, 20(8), pp. 1630-1637. Oxford University Press 10.1093/ndt/gfh880

Knüsel, Rafael Matthias; Jakob, Stephan M.; Brander, Lukas; Bracht, Hendrik; Siegenthaler, Andreas; Takala, Jukka (2003). Changes in regional blood flow and pCO2 gradients during isolated abdominal aortic blood flow reduction. Intensive care medicine, 29(12), pp. 2255-2265. Springer-Verlag 10.1007/s00134-003-1954-1

Röck, Margareta Anna; Jakob, Stephan M.; Böhlen, Thomas; Brander, Lukas; Knuesel, Rafael; Takala, Jukka (2003). Change in stroke volume in response to fluid challenge: assessment using esophageal Doppler. Intensive care medicine, 29(10), pp. 1729-1735. Springer-Verlag 10.1007/s00134-003-1720-4