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Subissi, Lorenzo; Otieno, James Richard; Worp, Nathalie; Attar Cohen, Homa; Oude Munnink, Bas B; Abu-Raddad, Laith J; Alm, Erik; Barakat, Amal; Barclay, Wendy S; Bhiman, Jinal N; Caly, Leon; Chand, Meera; Chen, Mark; Cullinane, Ann; de Oliveira, Tulio; Drosten, Christian; Druce, Julian; Effler, Paul; El Masry, Ihab; Faye, Adama; ... (2024). An updated framework for SARS-CoV-2 variants reflects the unpredictability of viral evolution. Nature medicine, 30(9), pp. 2400-2403. Springer Nature 10.1038/s41591-024-02949-0
Schön, Jacob; Barut, G Tuba; Trüeb, Bettina Salome; Halwe, Nico Joel; Berenguer Veiga, Inês; Kratzel, Annika; Ulrich, Lorenz; Kelly, Jenna N; Brügger, Melanie; Wylezich, Claudia; Taddeo, Adriano; Aguiar Moreira, Etori; Túrós, Demeter; Grau-Roma, Llorenç; Ahrens, Ann Kathrin; Schlottau, Kore; Britzke, Tobias; Breithaupt, Angele; Corleis, Björn; Kochmann, Jana; ... (2024). A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications. Nature microbiology, 9(8), pp. 2099-2112. Springer Nature 10.1038/s41564-024-01755-1
Gütlin, Yukino; Albertos Torres, Diana; Gensch, Alexander; Schlotterbeck, Ann-Kathrin; Stöger, Laurent; Heller, Stefanie; Infanti, Laura; Barut, Güliz Tuba; Thiel, Volker; Leuzinger, Karoline; Hirsch, Hans H; Buser, Andreas; Egli, Adrian (2024). Anti-SARS-CoV-2 total immunoglobulin and neutralising antibody responses in healthy blood donors throughout the COVID-19 pandemic: a longitudinal observational study. Swiss medical weekly, 154(3408) SMW supporting association 10.57187/s.3408
Leborgne, Nathan GF; Devisme, Christelle; Kozarac, Nedim; Berenguer Veiga, Inês; Ebert, Nadine; Godel, Aurélie; Grau Roma, Llorenç; Scherer, Melanie; Plattet, Philippe; Thiel, Volker; Zimmer, Gert; Taddeo, Adriano; Benarafa, Charaf (2024). Neutrophil proteases are protective against SARS-CoV-2 by degrading the spike protein and dampening virus-mediated inflammation. JCI insight, 9(7) JCI Insight 10.1172/jci.insight.174133
Steiner, Silvio; Kratzel, Annika; Barut, G Tuba; Lang, Reto M; Aguiar Moreira, Etori; Thomann, Lisa; Kelly, Jenna N; Thiel, Volker (2024). SARS-CoV-2 biology and host interactions. Nature reviews. Microbiology, 22(4), pp. 206-225. Springer Nature 10.1038/s41579-023-01003-z
Schmied, Kimberly; Ehmann, Rosina; Kristen-Burmann, Claudia; Ebert, Nadine; Barut, Güliz Tuba; Almeida, Lea; Kelly, Jenna N; Thomann, Lisa; Stalder, Hanspeter; Lang, Reto; Tekes, Gergely; Thiel, Volker (2024). An RNA replicon system to investigate promising inhibitors of feline coronavirus. Journal of virology, 98(2), e0121623. American Society for Microbiology 10.1128/jvi.01216-23
de Melo, Guilherme Dias; Perraud, Victoire; Alvarez, Flavio; Vieites-Prado, Alba; Kim, Seonhee; Kergoat, Lauriane; Coleon, Anthony; Trüeb, Bettina Salome; Tichit, Magali; Piazza, Aurèle; Thierry, Agnès; Hardy, David; Wolff, Nicolas; Munier, Sandie; Koszul, Romain; Simon-Lorière, Etienne; Thiel, Volker; Lecuit, Marc; Lledo, Pierre-Marie; Renier, Nicolas; ... (2023). Author Correction: Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants. Nature communications, 14(1), p. 8024. Nature Publishing Group 10.1038/s41467-023-42800-7
Daniels, Alison; Fletcher, Sarah; Kerr, Holly E M; Kratzel, Annika; Pinto, Rute Maria; Kriplani, Nisha; Craig, Nicky; Hastie, C James; Davies, Paul; Digard, Paul; Thiel, Volker; Tait-Burkard, Christine (2023). One for all-human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses. Journal of virology, 97(9), e0055523. American Society for Microbiology 10.1128/jvi.00555-23
Mhlekude, Baxolele; Postmus, Dylan; Stenzel, Saskia; Weiner, January; Jansen, Jenny; Zapatero-Belinchón, Francisco J; Olmer, Ruth; Richter, Anja; Heinze, Julian; Heinemann, Nicolas; Mühlemann, Barbara; Schroeder, Simon; Jones, Terry C; Müller, Marcel A; Drosten, Christian; Pich, Andreas; Thiel, Volker; Martin, Ulrich; Niemeyer, Daniela; Gerold, Gisa; ... (2023). Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection. PLoS pathogens, 19(9), e1011657. Public Library of Science 10.1371/journal.ppat.1011657
Kristen-Burmann, Claudia; Rogger, Peter; Berenguer Veiga, Inês; Riebesehl, Stefanie; Rappe, Julie; Ebert, Nadine; Sautter, Carmen A; Kelly, Jenna N; Stalder, Hanspeter; Ehmann, Rosina; Huber, Michael; Posthaus, Horst; Ruggli, Nicolas; Thiel, Volker; Tekes, Gergely (2023). Reverse Genetic Assessment of the Roles Played by the Spike Protein and ORF3 in Porcine Epidemic Diarrhea Virus Pathogenicity. Journal of virology, 97(7), e0196422. American Society for Microbiology 10.1128/jvi.01964-22
de Melo, Guilherme Dias; Perraud, Victoire; Alvarez, Flavio; Vieites-Prado, Alba; Kim, Seonhee; Kergoat, Lauriane; Coleon, Anthony; Trüeb, Bettina Salome; Tichit, Magali; Piazza, Aurèle; Thierry, Agnès; Hardy, David; Wolff, Nicolas; Munier, Sandie; Koszul, Romain; Simon-Lorière, Etienne; Thiel, Volker; Lecuit, Marc; Lledo, Pierre-Marie; Renier, Nicolas; ... (2023). Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants. Nature communications, 14(1), p. 4485. Nature Publishing Group 10.1038/s41467-023-40228-7
Kratzel, Annika; Thiel, Volker (2023). RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles. The Journal of cell biology, 222(7) Rockefeller Institute Press 10.1083/jcb.202306020
Radzikowska, Urszula; Eljaszewicz, Andrzej; Tan, Ge; Stocker, Nino; Heider, Anja; Westermann, Patrick; Steiner, Silvio; Dreher, Anita; Wawrzyniak, Paulina; Rückert, Beate; Rodriguez-Coira, Juan; Zhakparov, Damir; Huang, Mengting; Jakiela, Bogdan; Sanak, Marek; Moniuszko, Marcin; O'Mahony, Liam; Jutel, Marek; Kebadze, Tatiana; Jackson, David J; ... (2023). Author Correction: Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19. Nature Communications, 14(1), p. 3493. Springer Nature 10.1038/s41467-023-39275-x
Capoferri, Gioele; Walti, Carla Simone; Urwyler, Pascal; Ragozzino, Silvio; Passweg, Jakob R; Halter, Jörg; Battegay, Manuel; Baettig, Veronika; Weisser, Maja; Arnold, Brice; Morin, Benedict; Guetlin, Yukino; Torres, Diana Albertos; Barut, Güliz Tuba; Thiel, Volker; Egli, Adrian; Drexler, Beatrice; Khanna, Nina (2023). Dynamics of antibody titers to SARS-CoV-2 and clinical outcomes after sotrovimab pre-exposure prophylaxis early after allogeneic hematopoietic stem cell transplantation. Bone marrow transplantation, 58(5), pp. 597-599. Springer Nature 10.1038/s41409-023-01936-2
Radzikowska, Urszula; Eljaszewicz, Andrzej; Tan, Ge; Stocker, Nino; Heider, Anja; Westermann, Patrick; Steiner, Silvio; Dreher, Anita; Wawrzyniak, Paulina; Rückert, Beate; Rodriguez-Coira, Juan; Zhakparov, Damir; Huang, Mengting; Jakiela, Bogdan; Sanak, Marek; Moniuszko, Marcin; O'Mahony, Liam; Jutel, Marek; Kebadze, Tatiana; Jackson, J David; ... (2023). Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19. Nature communications, 14(1), p. 2329. Nature Publishing Group 10.1038/s41467-023-37470-4
Abdelnabi, Rana; Jochmans, Dirk; Donckers, Kim; Trüeb, Bettina; Ebert, Nadine; Weynand, Birgit; Thiel, Volker; Neyts, Johan (2023). Nirmatrelvir-resistant SARS-CoV-2 is efficiently transmitted in female Syrian hamsters and retains partial susceptibility to treatment. Nature communications, 14(1), p. 2124. Nature Publishing Group 10.1038/s41467-023-37773-6
Kahlert, Christian R; Nigg, Susanne; Onder, Lucas; Dijkman, Ronald; Diener, Liliane; Vidal, Ana G Jop; Rodriguez, Regulo; Vernazza, Pietro; Thiel, Volker; Vidal, Jorge E; Albrich, Werner C (2023). The quorum sensing com system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue model. Microbiological research, 268, p. 127297. Elsevier 10.1016/j.micres.2022.127297
Jochmans, Dirk; Liu, Cheng; Donckers, Kim; Stoycheva, Antitsa; Boland, Sandro; Stevens, Sarah K; De Vita, Chloe; Vanmechelen, Bert; Maes, Piet; Trüeb, Bettina; Ebert, Nadine; Thiel, Volker; De Jonghe, Steven; Vangeel, Laura; Bardiot, Dorothée; Jekle, Andreas; Blatt, Lawrence M; Beigelman, Leonid; Symons, Julian A; Raboisson, Pierre; ... (2023). The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir. mBio, 14(1), e0281522. American Society for Microbiology 10.1128/mbio.02815-22
Emmenegger, Marc; De Cecco, Elena; Lamparter, David; Jacquat, Raphaël P B; Riou, Julien; Menges, Dominik; Ballouz, Tala; Ebner, Daniel; Schneider, Mathias M; Morales, Itzel Condado; Doğançay, Berre; Guo, Jingjing; Wiedmer, Anne; Domange, Julie; Imeri, Marigona; Moos, Rita; Zografou, Chryssa; Batkitar, Leyla; Madrigal, Lidia; Schneider, Dezirae; ... (2023). Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region. iScience, 26(2), p. 105928. Elsevier 10.1016/j.isci.2023.105928
Brüggemann, Yannick; Kratzel, Annika; Almeida, Lea; Kelly, Jenna N; Thiel, Volker; Pfaender, Stephanie (2023). Conserved requirement of autophagy-related effectors during coronavirus replication. Autophagy, 19(2), pp. 731-733. Landes Bioscience 10.1080/15548627.2022.2100617
Chiu, Winston; Schepers, Joost; Francken, Thibault; Vangeel, Laura; Abbasi, Kayvan; Jochmans, Dirk; De Jonghe, Steven; Thibaut, Hendrik Jan; Thiel, Volker; Neyts, Johan; Laporte, Manon; Leyssen, Pieter (2023). Development of a robust and convenient dual-reporter high-throughput screening assay for SARS-CoV-2 antiviral drug discovery. Antiviral research, 210, p. 105506. Elsevier 10.1016/j.antiviral.2022.105506
Beer, Julius; Crotta, Stefania; Breithaupt, Angele; Ohnemus, Annette; Becker, Jan; Sachs, Benedikt; Kern, Lisa; Llorian, Miriam; Ebert, Nadine; Labroussaa, Fabien; Nhu Thao, Tran Thi; Trueeb, Bettina Salome; Jores, Joerg; Thiel, Volker; Beer, Martin; Fuchs, Jonas; Kochs, Georg; Wack, Andreas; Schwemmle, Martin and Schnepf, Daniel (2022). Impaired immune response drives age-dependent severity of COVID-19. The Journal of experimental medicine, 219(12) Rockefeller Univ. Press 10.1084/jem.20220621
Barut, G Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype. Nature Communications, 13(1), p. 5929. Springer Nature 10.1038/s41467-022-33632-y
Kelly, Jenna N; Laloli, Laura; V'kovski, Philip; Holwerda, Melle; Portmann, Jasmine; Thiel, Volker; Dijkman, Ronald (2022). Comprehensive single cell analysis of pandemic influenza A virus infection in the human airways uncovers cell-type specific host transcriptional signatures relevant for disease progression and pathogenesis. Frontiers in immunology, 13(978824), p. 978824. Frontiers Research Foundation 10.3389/fimmu.2022.978824
Taddeo, Adriano; Berenguer Veiga, Inês; Devisme, Christelle; Boss, Renate; Plattet, Philippe; Weigang, Sebastian; Kochs, Georg; Thiel, Volker; Benarafa, Charaf; Zimmer, Gert (2022). Optimized intramuscular immunization with VSV-vectored spike protein triggers a superior immune response to SARS-CoV-2. NPJ vaccines, 7(1), p. 82. Springer Nature 10.1038/s41541-022-00508-7
Brandys, Pascal; Montagutelli, Xavier; Merenkova, Irena; Barut, Güliz T; Thiel, Volker; Schork, Nicholas J; Trüeb, Bettina; Conquet, Laurine; Deng, Aihua; Antanasijevic, Aleksandar; Lee, Hyun-Ku; Valière, Martine; Sindhu, Anoop; Singh, Gita; Herold, Jens (2022). A mRNA Vaccine Encoding for a RBD 60-mer Nanoparticle Elicits Neutralizing Antibodies and Protective Immunity Against the SARS-CoV-2 Delta Variant in Transgenic K18-hACE2 Mice. Frontiers in immunology, 13(912898), p. 912898. Frontiers Research Foundation 10.3389/fimmu.2022.912898
Subissi, Lorenzo; von Gottberg, Anne; Thukral, Lipi; Worp, Nathalie; Oude Munnink, Bas B; Rathore, Surabhi; Abu-Raddad, Laith J; Aguilera, Ximena; Alm, Erik; Archer, Brett N; Attar Cohen, Homa; Barakat, Amal; Barclay, Wendy S; Bhiman, Jinal N; Caly, Leon; Chand, Meera; Chen, Mark; Cullinane, Ann; de Oliveira, Tulio; Drosten, Christian; ... (2022). An early warning system for emerging SARS-CoV-2 variants. Nature medicine, 28(6), pp. 1110-1115. Springer Nature 10.1038/s41591-022-01836-w
Wyss, Marianne; Gradauskaite, Vaiva; Ebert, Nadine; Thiel, Volker; Zurbriggen, Andreas; Plattet, Philippe (2022). Efficient Recovery of Attenuated Canine Distemper Virus from cDNA. Virus research, 316, p. 198796. Elsevier 10.1016/j.virusres.2022.198796
Rossetti, Giacomo G; Ossorio, Marianna A; Rempel, Stephan; Kratzel, Annika; Dionellis, Vasilis S; Barriot, Samia; Tropia, Laurence; Gorgulla, Christoph; Arthanari, Haribabu; Thiel, Volker; Mohr, Peter; Gamboni, Remo; Halazonetis, Thanos D (2022). Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits. Scientific reports, 12(1), p. 2505. Springer Nature 10.1038/s41598-022-06306-4
Hume, Adam J.; Heiden, Baylee; Olejnik, Judith; Suder, Ellen L.; Ross, Stephen; Scoon, Whitney A.; Bullitt, Esther; Ericsson, Maria; White, Mitchell R.; Turcinovic, Jacquelyn; Tran, T N Thao; Hekman, Ryan M.; Kaserman, Joseph E.; Huang, Jessie; Alysandratos, Konstantinos-Dionysios; Toth, Gabor E.; Jakab, Ferenc; Kotton, Darrell N.; Wilson, Andrew A.; Emili, Andrew; ... (2022). Recombinant Lloviu virus as a tool to study viral replication and host responses. PLoS pathogens, 18(2), e1010268. Public Library of Science 10.1371/journal.ppat.1010268
Pan, Ruangang; Kindler, Eveline; Cao, Liu; Zhou, Yu; Zhang, Zhen; Liu, Qianyun; Ebert, Nadine; Züst, Roland; Sun, Ying; Gorbalenya, Alexander E.; Perlman, Stanley; Thiel, Volker; Chen, Yu; Guo, Deyin; Britton, Paul; Schultz-Cherry, Stacey (2022). N7-Methylation of the Coronavirus RNA Cap Is Required for Maximal Virulence by Preventing Innate Immune Recognition. mBio, 13(1), e0366221. American Society for Microbiology 10.1128/mbio.03662-21
Niemeyer, Daniela; Stenzel, Saskia; Veith, Talitha; Schroeder, Simon; Friedmann, Kirstin; Weege, Friderike; Trimpert, Jakob; Heinze, Julian; Richter, Anja; Jansen, Jenny; Emanuel, Jackson; Kazmierski, Julia; Pott, Fabian; Jeworowski, Lara M.; Olmer, Ruth; Jaboreck, Mark-Christian; Tenner, Beate; Papies, Jan; Walper, Felix; Schmidt, Marie L.; ... (2022). SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression. PLoS biology, 20(11), e3001871. Public Library of Science 10.1371/journal.pbio.3001871
Thomann, Lisa; Thiel, Volker (2022). SARS-CoV-2 mimics a host protein to bypass defences. Nature, 610(7931), pp. 262-263. Springer Nature 10.1038/d41586-022-02930-2
Kratzel, Annika; Kelly, Jenna N; V'kovski, Philip; Portmann, Jasmine; Brüggemann, Yannick; Todt, Daniel; Ebert, Nadine; Shrestha, Neeta; Plattet, Philippe; Staab-Weijnitz, Claudia A; von Brunn, Albrecht; Steinmann, Eike; Dijkman, Ronald; Zimmer, Gert; Pfaender, Stephanie; Thiel, Volker (2021). A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets. PLoS biology, 19(12), e3001490. Public Library of Science 10.1371/journal.pbio.3001490
Ulrich, Lorenz; Halwe, Nico Joel; Taddeo, Adriano; Ebert, Nadine; Schön, Jacob; Devisme, Christelle; Trüeb, Bettina Salome; Hoffmann, Bernd; Wider, Manon; Fan, Xiaoyu; Bekliz, Meriem; Essaidi-Laziosi, Manel; Schmidt, Marie Luisa; Niemeyer, Daniela; Corman, Victor Max; Kraft, Anna; Godel, Aurélie; Laloli, Laura; Kelly, Jenna N; Calderon, Brenda M; ... (2022). Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta. Nature, 602(7896), pp. 307-313. Springer Nature 10.1038/s41586-021-04342-0
Fahmi, Amal; Brügger, Melanie; Démoulins, Thomas; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Bracher, Lisamaria; Wotzkow, Carlos; Blank, Fabian; Thiel, Volker; Baud, David; Alves, Marco P. (2021). SARS-CoV-2 can infect and propagate in human placenta explants. Cell reports. Medicine, 2(12), p. 100456. Elsevier 10.1016/j.xcrm.2021.100456
Tabata, Keisuke; Prasad, Vibhu; Paul, David; Lee, Ji-Young; Pham, Minh-Tu; Twu, Woan-Ing; Neufeldt, Christopher J; Cortese, Mirko; Cerikan, Berati; Stahl, Yannick; Joecks, Sebastian; Tran, Cong Si; Lüchtenborg, Christian; V'kovski, Philip; Hörmann, Katrin; Müller, André C; Zitzmann, Carolin; Haselmann, Uta; Beneke, Jürgen; Kaderali, Lars; ... (2021). Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation. Nature Communications, 12(1), p. 7276. Springer Nature 10.1038/s41467-021-27511-1
Ogando, Natacha S; El Kazzi, Priscila; Zevenhoven-Dobbe, Jessika C; Bontes, Brenda W; Decombe, Alice; Posthuma, Clara C; Thiel, Volker; Canard, Bruno; Ferron, François; Decroly, Etienne; Snijder, Eric J (2021). Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 118(49) National Academy of Sciences NAS 10.1073/pnas.2108709118
Trimpert, Jakob; Adler, Julia M; Eschke, Kathrin; Abdelgawad, Azza; Firsching, Theresa C; Ebert, Nadine; Tran, Thi Nhu Thao; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan (2021). Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B.1.1.7 (Alpha) and B.1.351 (Beta). Science Advances, 7(49), eabk0172. American Association for the Advancement of Science 10.1126/sciadv.abk0172
Ricardo-Lax, Inna; Luna, Joseph M; Tran, Thi Nhu Thao; Le Pen, Jérémie; Yu, Yingpu; Hoffmann, H-Heinrich; Schneider, William M; Razooky, Brandon S; Fernandez-Martinez, Javier; Schmidt, Fabian; Weisblum, Yiska; Trüeb, Bettina Salome; Berenguer Veiga, Inês; Schmied, Kimberly; Ebert, Nadine; Michailidis, Eleftherios; Peace, Avery; Sánchez-Rivera, Francisco J; Lowe, Scott W; Rout, Michael P; ... (2021). Replication and single-cycle delivery of SARS-CoV-2 replicons. Science, 374(6571), pp. 1099-1106. American Association for the Advancement of Science 10.1126/science.abj8430
Fenwick, Craig; Turelli, Priscilla; Perez, Laurent; Pellaton, Céline; Esteves-Leuenberger, Line; Farina, Alex; Campos, Jérémy; Lana, Erica; Fiscalini, Flurin; Raclot, Charlène; Pojer, Florence; Lau, Kelvin; Demurtas, Davide; Descatoire, Marc; Joo, Victor S; Foglierini, Mathilde; Noto, Alessandra; Abdelnabi, Rana; Foo, Caroline S; Vangeel, Laura; ... (2021). A highly potent antibody effective against SARS-CoV-2 variants of concern. Cell reports, 37(2), p. 109814. Cell Press 10.1016/j.celrep.2021.109814
Schroeder, Simon; Mache, Christin; Kleine-Weber, Hannah; Corman, Victor M; Muth, Doreen; Richter, Anja; Fatykhova, Diana; Memish, Ziad A; Stanifer, Megan L; Boulant, Steeve; Gultom, Mitra; Dijkman, Ronald; Eggeling, Stephan; Hocke, Andreas; Hippenstiel, Stefan; Thiel, Volker; Pöhlmann, Stefan; Wolff, Thorsten; Müller, Marcel A and Drosten, Christian (2021). Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5. Nature Communications, 12(1), p. 5324. Springer Nature 10.1038/s41467-021-25519-1
Trimpert, Jakob; Dietert, Kristina; Firsching, Theresa C; Ebert, Nadine; Tran, Thi Nhu Thao; Vladimirova, Daria; Kaufer, Susanne; Labroussaa, Fabien; Abdelgawad, Azza; Conradie, Andelé; Höfler, Thomas; Adler, Julia M; Bertzbach, Luca D; Jores, Jörg; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan (2021). Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding. Cell reports, 36(5), p. 109493. Cell Press 10.1016/j.celrep.2021.109493
Gultom, Mitra; Licheri, Matthias; Laloli, Laura; Wider, Manon; Strässle, Marina; V'kovski, Philip; Steiner, Silvio; Kratzel, Annika; Tran, Thi Nhu Thao; Probst, Lukas; Stalder, Hanspeter; Portmann, Jasmine; Holwerda, Melle; Ebert, Nadine; Stokar-Regenscheit, Nadine; Gurtner, Corinne; Zanolari, Patrik; Posthaus, Horst; Schuller, Simone; Vicente-Santos, Amanda; ... (2021). Susceptibility of Well-Differentiated Airway Epithelial Cell Cultures from Domestic and Wild Animals to Severe Acute Respiratory Syndrome Coronavirus 2. Emerging infectious diseases, 27(7), pp. 1811-1820. Centers for Disease Control and Prevention 10.3201/eid2707.204660
Konings, Frank; Perkins, Mark D; Kuhn, Jens H; Pallen, Mark J; Alm, Erik J; Archer, Brett N; Barakat, Amal; Bedford, Trevor; Bhiman, Jinal N; Caly, Leon; Carter, Lisa L; Cullinane, Anne; de Oliveira, Tulio; Druce, Julian; El Masry, Ihab; Evans, Roger; Gao, George F; Gorbalenya, Alexander E; Hamblion, Esther; Herring, Belinda L; ... (2021). SARS-CoV-2 Variants of Interest and Concern naming scheme conducive for global discourse [comment]. Nature microbiology, 6(7), pp. 821-823. Springer Nature 10.1038/s41564-021-00932-w
Bhatt, Pramod R; Scaiola, Alain; Loughran, Gary; Leibundgut, Marc; Kratzel, Annika; Meurs, Romane; Dreos, René; O'Connor, Kate M; McMillan, Angus; Bode, Jeffrey W; Thiel, Volker; Gatfield, David; Atkins, John F; Ban, Nenad (2021). Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372(6548), pp. 1306-1313. American Association for the Advancement of Science 10.1126/science.abf3546
Lei, Jian; Ma-Lauer, Yue; Han, Yinze; Thoms, Matthias; Buschauer, Robert; Jores, Joerg; Thiel, Volker; Beckmann, Roland; Deng, Wen; Leonhardt, Heinrich; Hilgenfeld, Rolf; von Brunn, Albrecht (2021). The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation. The EMBO journal, 40(11), e102277. EMBO Press 10.15252/embj.2019102277
Stukalov, Alexey; Girault, Virginie; Grass, Vincent; Karayel, Ozge; Bergant, Valter; Urban, Christian; Haas, Darya A; Huang, Yiqi; Oubraham, Lila; Wang, Anqi; Hamad, M Sabri; Piras, Antonio; Hansen, Fynn M; Tanzer, Maria C; Paron, Igor; Zinzula, Luca; Engleitner, Thomas; Reinecke, Maria; Lavacca, Teresa M; Ehmann, Rosina; ... (2021). Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature, 594(7862), pp. 246-252. Springer Nature 10.1038/s41586-021-03493-4
Strässle, Marina; Laloli, Laura; Gultom, Mitra; V'kovski, Philip; Stoffel, Michael H.; Crespo Pomar, Silvia; Chanfon Bätzner, Astrid; Ebert, Nadine; Labroussaa, Fabien; Dijkman, Ronald; Jores, Joerg; Thiel, Volker (2021). Establishment of caprine airway epithelial cells grown in an air-liquid interface system to study caprine respiratory viruses and bacteria. Veterinary microbiology, 257, p. 109067. Elsevier 10.1016/j.vetmic.2021.109067
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Garcia Nicolas, Obdulio; V'kovski, Philip; Zettl, Ferdinand; Zimmer, Gert; Thiel, Volker; Summerfield, Artur (2021). No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection. Frontiers in cellular and infection microbiology, 11(644574), p. 644574. Frontiers 10.3389/fcimb.2021.644574
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Meng, Xiang-Jin; Thiel, Volker (2020). Emerging and re-emerging porcine viruses. Virus research, 290, p. 198198. Elsevier 10.1016/j.virusres.2020.198198
Gasbarri, Matteo; V'kovski, Philip; Torriani, Giulia; Thiel, Volker; Stellacci, Francesco; Tapparel, Caroline; Cagno, Valeria (2020). SARS-CoV-2 Inhibition by Sulfonated Compounds. Microorganisms, 8(12) MDPI 10.3390/microorganisms8121894
Holwerda, Melle; V'kovski, Philip; Wider, Manon; Thiel, Volker; Dijkman, Ronald (2020). Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In Vitro. Microorganisms, 8(12) MDPI 10.3390/microorganisms8121872
Pfaender, Stephanie; Mar, Katrina B; Michailidis, Eleftherios; Kratzel, Annika; Boys, Ian N; V'kovski, Philip; Fan, Wenchun; Kelly, Jenna N.; Hirt, Dagny; Ebert, Nadine; Stalder, Hanspeter; Kleine-Weber, Hannah; Hoffmann, Markus; Heinrich Hoffmann, H; Saeed, Mohsan; Dijkman, Ronald; Steinmann, Eike; Wight-Carter, Mary; McDougal, Matthew B; Hanners, Natasha W; ... (2020). LY6E impairs coronavirus fusion and confers immune control of viral disease. Nature microbiology, 5(11), pp. 1330-1339. Springer Nature 10.1038/s41564-020-0769-y
Schubert, Katharina; Karousis, Evangelos D.; Jomaa, Ahmad; Scaiola, Alain; Echeverria, Blanca; Gurzeler, Lukas-Adrian; Leibundgut, Marc; Thiel, Volker; Mühlemann, Oliver; Ban, Nenad (2020). SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nature structural & molecular biology, 27(10), pp. 959-966. Springer Nature 10.1038/s41594-020-0511-8
Kratzel, Annika; Steiner, Silvio; Todt, Daniel; V'kovski, Philip; Brueggemann, Yannick; Steinmann, Joerg; Steinmann, Eike; Thiel, Volker; Pfaender, Stephanie (2020). Temperature-dependent surface stability of SARS-CoV-2. Journal of infection, 81(3), pp. 452-482. Elsevier 10.1016/j.jinf.2020.05.074
Kratzel, Annika; Todt, Daniel; V'kovski, Philip; Steiner, Silvio; Gultom, Mitra; Tran, Thi Nhu Thao; Ebert, Nadine; Holwerda, Melle; Steinmann, Jörg; Niemeyer, Daniela; Dijkman, Ronald; Kampf, Günter; Drosten, Christian; Steinmann, Eike; Thiel, Volker; Pfaender, Stephanie (2020). Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols. Emerging infectious diseases, 26(7), pp. 1592-1595. Centers for Disease Control and Prevention 10.3201/eid2607.200915
Tran, Thi Nhu Thao; Labroussaa, Fabien; Ebert, Nadine; V'kovski, Philip; Stalder, Hanspeter; Portmann, Jasmine; Kelly, Jenna; Steiner, Silvio; Holwerda, Melle; Kratzel, Annika; Gultom, Mitra; Schmied, Kimberly; Laloli, Laura; Hüsser, Linda; Wider, Manon; Pfaender, Stephanie; Hirt, Dagny; Cippà, Valentina; Crespo-Pomar, Silvia; Schröder, Simon; ... (2020). Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature, 582(7813), pp. 561-565. Springer Nature 10.1038/s41586-020-2294-9
Blockus, Sebastian; Sake, Svenja M; Wetzke, Martin; Grethe, Christina; Graalmann, Theresa; Pils, Marina; Le Goffic, Ronan; Galloux, Marie; Prochnow, Hans; Rox, Katharina; Hüttel, Stephan; Rupcic, Zeljka; Wiegmann, Bettina; Dijkman, Ronald; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Duprex, W Paul; Thiel, Volker; Hansen, Gesine; Brönstrup, Mark; ... (2020). Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. Antiviral research, 177, p. 104774. Elsevier 10.1016/j.antiviral.2020.104774
Thiel, Volker; Jores, Jörg (2020). Ein Klon geht um die Welt. Pipette - Swiss laboratory medicine(2), pp. 16-17. EMH Schweizerischer Ärzteverlag AG
Thiel, Volker (2020). Viral RNA in an m6A disguise. Nature microbiology, 5(4), pp. 531-532. Springer Nature 10.1038/s41564-020-0689-x
Cong, Yingying; Ulasli, Mustafa; Schepers, Hein; Mauthe, Mario; V'kovski, Philip; Kriegenburg, Franziska; Thiel, Volker; de Haan, Cornelis A M; Reggiori, Fulvio (2020). Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle. Journal of virology, 94(4) American Society for Microbiology 10.1128/JVI.01925-19
V'kovski, Philip; Steiner, Silvio; Thiel, Volker (2020). Proximity Labeling for the Identification of Coronavirus-Host Protein Interactions. Methods in molecular biology, 2203, pp. 187-204. Springer 10.1007/978-1-0716-0900-2_14
Tran, Thi Nhu Thao; Labroussaa, Fabien; Ebert, Nadine; Jores, Jörg; Thiel, Volker (2020). In-Yeast Assembly of Coronavirus Infectious cDNA Clones Using a Synthetic Genomics Pipeline. Methods in molecular biology, 2203, pp. 167-184. Springer 10.1007/978-1-0716-0900-2_13
Zhao, Ye; Cheng, Jinlong; Xu, Gang; Thiel, Volker; Zhang, Guozhong (2019). Successful establishment of a reverse genetic system for QX-type infectious bronchitis virus and technical improvement of the rescue procedure. Virus research, 272, p. 197726. Elsevier 10.1016/j.virusres.2019.197726
Jonsdottir, Hulda R.; Marti, Sabrina; Geerts, Dirk; Rodriguez, Regulo; Thiel, Volker; Dijkman, Ronald (2019). Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions. Viruses, 11(8) MDPI 10.3390/v11080747
Kratzel, Annika; Thiel, Volker; Pfaender, Stephanie (2019). Zoonotic coronavirus infections. Pipette - Swiss laboratory medicine(4), pp. 18-19. EMH Schweizerischer Ärzteverlag AG
Contu, Lara; Steiner, Silvio; Thiel, Volker; Mühlemann, Oliver (2019). The Role of Stress Granules and the Nonsense-mediated mRNA Decay Pathway in Antiviral Defence. CHIMIA, 73(6), pp. 374-379. Schweizerische Chemische Gesellschaft 10.2533/chimia.2019.374
Hufsky, Franziska; Ibrahim, Bashar; Modha, Sejal; Clokie, Martha R J; Deinhardt-Emmer, Stefanie; Dutilh, Bas E; Lycett, Samantha; Simmonds, Peter; Thiel, Volker; Abroi, Aare; Adriaenssens, Evelien M; Escalera-Zamudio, Marina; Kelly, Jenna Nicole; Lamkiewicz, Kevin; Lu, Lu; Susat, Julian; Sicheritz, Thomas; Robertson, David L; Marz, Manja (2019). The Third Annual Meeting of the European Virus Bioinformatics Center. Viruses, 11(5) MDPI 10.3390/v11050420
Garcia Nicolas, Obdulio; V'kovski, Philip; Vielle, Nathalie J.; Ebert, Nadine; Züst, R; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Vieyres, G; Stoffel, Michael; Schweizer, Matthias; Summerfield, Artur; Engler, O; Pietschmann, T; Todt, D; Alves, Marco; Thiel, Volker; Pfänder, Stephanie (2018). The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor. Antimicrobial agents and chemotherapy, 62(11) American Society for Microbiology 10.1128/AAC.01206-18
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Greub, Gilbert; Holliger, Christof; Sanglard, Dominique; Schrenzel, Jacques; Thiel, Volker; Viollier, Patrick (2016). The Swiss Society of Microbiology: Small Bugs, Big Questions and Cool Answers. CHIMIA, 70(12), pp. 874-877. Schweizerische Chemische Gesellschaft 10.2533/chimia.2016.874
Corman, Victor M; Eckerle, Isabella; Memish, Ziad A; Liljander, Anne M; Dijkman, Ronald; Jonsdottir, Hulda; Juma Ngeiywa, Kisi J Z; Kamau, Esther; Younan, Mario; Al Masri, Malakita; Assiri, Abdullah; Gluecks, Ilona; Musa, Bakri E; Meyer, Benjamin; Müller, Marcel A; Hilali, Mosaad; Bornstein, Set; Wernery, Ulrich; Thiel, Volker; Jores, Jörg; ... (2016). Link of a ubiquitous human coronavirus to dromedary camels. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(35), pp. 9864-9869. National Academy of Sciences NAS 10.1073/pnas.1604472113
Ionescu, Danny; Heim, Christine; Polerecky, Lubos; Ramette, Alban Nicolas; Haeusler, Stefan; Bizic-Ionescu, Mina; Thiel, Volker; de Beer, Dirk (2015). Diversity of Iron Oxidizing and Reducing Bacteria in Flow Reactors in the Äspö Hard Rock Laboratory. Geomicrobiology Journal, 32(3-4), pp. 207-220. Taylor & Francis 10.1080/01490451.2014.884196
Dijkman, Ronald; Jebbink, Maarten F; Koekkoek, Sylvie M; Deijs, Martin; Jonsdottir, Hulda R.; Molenkamp, Richard; Ieven, Margareta; Goossens, Herman; Thiel, Volker; van der Hoek, Lia (2013). Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism. Journal of virology, 87(11), pp. 6081-6090. American Society for Microbiology 10.1128/JVI.03368-12
Chai, Qian; Onder, Lucas; Scandella, Elke; Gil-Cruz, Cristina; Perez-Shibayama, Christian; Cupovic, Jovana; Danuser, Renzo; Sparwasser, Tim; Luther, Sanjiv A.; Thiel, Volker; Rülicke, Thomas; Stein, Jens Volker; Hehlgans, Thomas; Ludewig, Burkhard (2013). Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity, 38(5), pp. 1013-1024. Cell Press 10.1016/j.immuni.2013.03.012
Kindler, Eveline; Jonsdottir, Hulda R.; Muth, Doreen; Hamming, Ole J; Hartmann, Rune; Rodriguez, Regulo; Geffers, Robert; Fouchier, Ron A M; Drosten, Christian; Müller, Marcel A; Dijkman, Ronald; Thiel, Volker (2013). Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential. mBio, 4(1), e00611-e00612. American Society for Microbiology 10.1128/mBio.00611-12
Ludewig, Burkhard; Stein, Jens V; Sharpe, James; Cervantes-Barragan, Luisa; Thiel, Volker; Bocharov, Gennady (2012). A global ”imaging” view on systems approaches in immunology. European journal of immunology, 42(12), pp. 3116-25. Weinheim: Wiley-VCH 10.1002/eji.201242508
Barut, Tuba; Halwe, Nico Joel; Taddeo, Adriano; Kelly, Jenna N.; Schön, Jacob; Ebert, Nadine; Ulrich, Lorenz; Devisme, Christelle; Steiner, Silvio; Trüeb, Bettina Salome; Hoffmann, Bernd; Berenguer Veiga, Inês; Leborgne, Nathan Georges François; Aguiar Moreira, Etori; Breithaupt, Angele; Wylezich, Claudia; Höper, Dirk; Wernike, Kerstin; Godel, Aurélie; Thomann, Lisa; ... (2022). The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA. 1 phenotype (bioRxiv). Cold Spring Harbor Laboratory
