Thiel, Volker Earl

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2018

Garcia Nicolas, Obdulio; V'kovski, Philip; Vielle, Nathalie J.; Ebert, Nadine; Züst, R; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Vieyres, G; Stoffel, Michael; Schweizer, Matthias; Summerfield, Artur; Engler, O; Pietschmann, T; Todt, D; Alves, Marco; Thiel, Volker; Pfänder, Stephanie (2018). The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor. Antimicrobial agents and chemotherapy, 62(11) American Society for Microbiology 10.1128/AAC.01206-18

V'kovski, Philip; Gerber, M; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga, Sophie Marie-Pierre; Simillion, Cedric André Marie; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (14 September 2018). Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling (Unpublished) (bioRxiv). Cold Spring Harbr Laboratory 10.1101/417907

Milewska, Aleksandra; Kindler, Eveline Patricia; V'Kovski, Philip; Zeglen, S; Ochman, M; Thiel, Volker Earl; Rajfur, Z; Pyrc, K (2018). APOBEC3-mediated restriction of RNA virus replication. Scientific Reports, 8(1), p. 5960. Nature Publishing Group 10.1038/s41598-018-24448-2

Rappe, Julie Christiane Françoise; de Wilde, Adriaan; Di, Han; Müller, Christin; Stalder, Hanspeter; V'Kovski, Philip; Snijder, Eric; Brinton, Margo A; Ziebuhr, John; Ruggli, Nicolas; Thiel, Volker Earl (2018). Antiviral activity of K22 against members of the order Nidovirales. Virus research, 246, pp. 28-34. Elsevier 10.1016/j.virusres.2018.01.002

2017

Behrendt, Patrick; Perin, Paula; Menzel, Nicolas; Banda, Dominic; Pfänder, Stephanie; Alves, Marco; Thiel, Volker Earl; Meulemann, Phillip; Colpitts, Che C; Schang, Luis M; Vondran, Florian W R; Anggakusuma, A; Manns, Michael P; Steinmann, Eike; Pietschmann, Thomas (2017). Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral research, 147, pp. 19-28. Elsevier 10.1016/j.antiviral.2017.09.006

Pfänder, Stephanie; Walter, Stephanie; Grabski, Elena; Todt, Daniel; Bruening, Janina; Romero-Brey, Inés; Gather, Theresa; Brown, Richard J P; Hahn, Kerstin; Puff, Christina; Pfankuche, Vanessa M; Hansmann, Florian; Postel, Alexander; Becher, Paul; Thiel, Volker Earl; Kalinke, Ulrich; Wagner, Bettina; Bartenschlager, Ralf; Baumgärtner, Wolfgang; Feige, Karsten; ... (2017). Immune protection against reinfection with nonprimate hepacivirus. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(12), E2430-E2439. National Academy of Sciences NAS 10.1073/pnas.1619380114

Siddharta, Anindya; Pfänder, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker Earl; Steinmann, Eike (2017). Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. Journal of infectious diseases, 215(6), pp. 902-906. Oxford University Press 10.1093/infdis/jix046

Kindler, Eveline Patricia; Gil-Cruz, Cristina; Spanier, Julia; Li, Yize; Wilhelm, Jochen; Rabouw, Huib H; Züst, Roland; Hwang, Mihyun; V'Kovski, Philip; Stalder, Hanspeter; Marti, Sabrina; Habjan, Matthias; Cervantes-Barragan, Luisa; Elliot, Ruth; Karl, Nadja; Gaughan, Christina; van Kuppeveld, Frank J M; Silverman, Robert H; Keller, Markus; Ludewig, Burkhard; ... (2017). Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens, 13(2), e1006195. Public Library of Science 10.1371/journal.ppat.1006195

Pfänder, Stephanie; Vielle, Nathalie Jane; Ebert, Nadine; Steinmann, E; Alves, Marco; Thiel, Volker Earl (2017). Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization. Virus research, 228, pp. 58-60. Elsevier 10.1016/j.virusres.2016.11.025

2016

Wu, Nai-Huei; Yang, Wei; Beineke, Andreas; Dijkman, Ronald; Matrosovich, Mikhail; Baumgärtner, Wolfgang; Thiel, Volker Earl; Valentin-Weigand, Peter; Meng, Fandan; Herrler, Georg (2016). The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells. Scientific Reports, 6(39668), p. 39668. Nature Publishing Group 10.1038/srep39668

Greub, Gilbert; Holliger, Christof; Sanglard, Dominique; Schrenzel, Jacques; Thiel, Volker; Viollier, Patrick (2016). The Swiss Society of Microbiology: Small Bugs, Big Questions and Cool Answers. CHIMIA, 70(12), pp. 874-877. Schweizerische Chemische Gesellschaft 10.2533/chimia.2016.874

Corman, Victor M; Eckerle, Isabella; Memish, Ziad A; Liljander, Anne M; Dijkman, Ronald; Jonsdottir, Hulda; Juma Ngeiywa, Kisi J Z; Kamau, Esther; Younan, Mario; Al Masri, Malakita; Assiri, Abdullah; Gluecks, Ilona; Musa, Bakri E; Meyer, Benjamin; Müller, Marcel A; Hilali, Mosaad; Bornstein, Set; Wernery, Ulrich; Thiel, Volker; Jores, Jörg; ... (2016). Link of a ubiquitous human coronavirus to dromedary camels. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(35), pp. 9864-9869. National Academy of Sciences NAS 10.1073/pnas.1604472113

Kaderali, Lars; Thiel, Volker Earl (2016). Systems biology of viral infection. Virus research, 218, p. 1. Elsevier 10.1016/j.virusres.2016.05.020

Kindler, Eveline Patricia; Thiel, Volker Earl (2016). SARS-CoV and IFN: Too Little, Too Late. Cell host & microbe, 19(2), pp. 139-141. Cell Press 10.1016/j.chom.2016.01.012

Kindler, Eveline Patricia; Thiel, Volker Earl; Weber, F (2016). Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. Advances in virus research, 96, pp. 219-243. Elsevier 10.1016/bs.aivir.2016.08.006

2015

Corman, Victor Max; Baldwin, Heather J; Tateno, Adriana Fumie; Zerbinati, Rodrigo Melim; Annan, Augustina; Owusu, Michael; Nkrumah, Evans Ewald; Maganga, Gael Darren; Oppong, Samuel; Adu-Sarkodie, Yaw; Vallo, Peter; da Silva Filho, Luiz Vicente Ribeiro Ferreira; Leroy, Eric M; Thiel, Volker Earl; van der Hoek, Lia; Poon, Leo L M; Tschapka, Marco; Drosten, Christian; Drexler, Jan Felix (2015). Evidence for an Ancestral Association of Human Coronavirus 229E with Bats. Journal of virology, 89(23), pp. 11858-11870. American Society for Microbiology 10.1128/JVI.01755-15

Lauber, C; Vieyres, G; Terczyńska-Dyla, E; Anggakusuma, X; Dijkman, Ronald; Gad, H H; Akhtar, H; Geffers, R; Vondran, F W R; Thiel, Volker Earl; Kaderali, L; Pietschmann, T; Hartmann, R (2015). Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. Genes and immunity, 16(6), pp. 414-421. Nature Publishing Group 10.1038/gene.2015.23

Mielech, Anna M; Deng, Xufang; Chen, Yafang; Kindler, Eveline Patricia; Wheeler, Dorthea L; Mesecar, Andrew D; Thiel, Volker Earl; Perlman, Stanley; Baker, Susan C (2015). Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. Journal of virology, 89(9), pp. 4907-4917. American Society for Microbiology 10.1128/JVI.00338-15

V'Kovski, Philip; Al-Mulla, Hawaa; Thiel, Volker Earl; Neuman, Benjamin W (2015). New insights on the role of paired membrane structures in coronavirus replication. Virus research, 202, pp. 33-40. Elsevier 10.1016/j.virusres.2014.12.021

Pas, Suzan D.; Patel, Pranav; Reusken, Chantal; Domingo, Cristina; Corman, Victor M.; Drosten, Christian; Dijkman, Ronald; Thiel, Volker Earl; Nowotny, Norbert; Koopmans, Marion P.G.; Niedrig, Matthias (2015). First international external quality assessment of molecular diagnostics for Mers-CoV. Journal of clinical virology, 69, pp. 81-85. Elsevier 10.1016/j.jcv.2015.05.022

2014

Kindler, E; Thiel, Volker Earl (2014). To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion. Current opinion in microbiology, 20, pp. 69-75. Elsevier 10.1016/j.mib.2014.05.005

Lundin, Anna; Dijkman, Ronald; Bergström, Tomas; Kann, Nina; Adamiak, Beata; Hannoun, Charles; Kindler, Eveline; Jónsdóttir, Hulda R; Muth, Doreen; Kint, Joeri; Forlenza, Maria; Müller, Marcel A; Drosten, Christian; Thiel, Volker Earl; Trybala, Edward (2014). Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS pathogens, 10(5), e1004166. Public Library of Science 10.1371/journal.ppat.1004166

Al-Mulla, Hawaa M N; Turrell, Lauren; Smith, Nicola M; Payne, Luke; Baliji, Surendranath; Züst, Roland; Thiel, Volker Earl; Baker, Susan C; Siddell, Stuart G; Neuman, Benjamin W (2014). Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. mBio, 5(2), e01107-e01113. American Society for Microbiology 10.1128/mBio.01107-13

Thiel, Volker Earl; Thiel, Heinz-Jürgen; Tekes, Gergely (2014). Tackling feline infectious peritonitis via reverse genetics. Bioengineered, 5(6), pp. 396-400. Taylor & Francis 10.4161/bioe.32133

2013

Dijkman, Ronald; Jebbink, Maarten F; Koekkoek, Sylvie M; Deijs, Martin; Jonsdottir, Hulda R.; Molenkamp, Richard; Ieven, Margareta; Goossens, Herman; Thiel, Volker; van der Hoek, Lia (2013). Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism. Journal of virology, 87(11), pp. 6081-6090. American Society for Microbiology 10.1128/JVI.03368-12

Kindler, Eveline; Jonsdottir, Hulda R.; Muth, Doreen; Hamming, Ole J; Hartmann, Rune; Rodriguez, Regulo; Geffers, Robert; Fouchier, Ron A M; Drosten, Christian; Müller, Marcel A; Dijkman, Ronald; Thiel, Volker (2013). Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential. mBio, 4(1), e00611-e00612. American Society for Microbiology 10.1128/mBio.00611-12

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