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Beer, Julius; Crotta, Stefania; Breithaupt, Angele; Ohnemus, Annette; Becker, Jan; Sachs, Benedikt; Kern, Lisa; Llorian, Miriam; Ebert, Nadine; Labroussaa, Fabien; Nhu Thao, Tran Thi; Trueeb, Bettina Salome; Jores, Joerg; Thiel, Volker; Beer, Martin; Fuchs, Jonas; Kochs, Georg; Wack, Andreas; Schwemmle, Martin and Schnepf, Daniel (2022). Impaired immune response drives age-dependent severity of COVID-19. The Journal of experimental medicine, 219(12) Rockefeller Univ. Press 10.1084/jem.20220621
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Ogando, Natacha S; El Kazzi, Priscila; Zevenhoven-Dobbe, Jessika C; Bontes, Brenda W; Decombe, Alice; Posthuma, Clara C; Thiel, Volker; Canard, Bruno; Ferron, François; Decroly, Etienne; Snijder, Eric J (2021). Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 118(49) National Academy of Sciences NAS 10.1073/pnas.2108709118
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Pfaender, Stephanie; Mar, Katrina B; Michailidis, Eleftherios; Kratzel, Annika; Boys, Ian N; V'kovski, Philip; Fan, Wenchun; Kelly, Jenna N.; Hirt, Dagny; Ebert, Nadine; Stalder, Hanspeter; Kleine-Weber, Hannah; Hoffmann, Markus; Heinrich Hoffmann, H; Saeed, Mohsan; Dijkman, Ronald; Steinmann, Eike; Wight-Carter, Mary; McDougal, Matthew B; Hanners, Natasha W; ... (2020). LY6E impairs coronavirus fusion and confers immune control of viral disease. Nature microbiology, 5(11), pp. 1330-1339. Springer Nature 10.1038/s41564-020-0769-y
Schubert, Katharina; Karousis, Evangelos D.; Jomaa, Ahmad; Scaiola, Alain; Echeverria, Blanca; Gurzeler, Lukas-Adrian; Leibundgut, Marc; Thiel, Volker; Mühlemann, Oliver; Ban, Nenad (2020). SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nature structural & molecular biology, 27(10), pp. 959-966. Springer Nature 10.1038/s41594-020-0511-8
Kratzel, Annika; Steiner, Silvio; Todt, Daniel; V'kovski, Philip; Brueggemann, Yannick; Steinmann, Joerg; Steinmann, Eike; Thiel, Volker; Pfaender, Stephanie (2020). Temperature-dependent surface stability of SARS-CoV-2. Journal of infection, 81(3), pp. 452-482. Elsevier 10.1016/j.jinf.2020.05.074
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Tran, Thi Nhu Thao; Labroussaa, Fabien; Ebert, Nadine; Jores, Jörg; Thiel, Volker (2020). In-Yeast Assembly of Coronavirus Infectious cDNA Clones Using a Synthetic Genomics Pipeline. Methods in molecular biology, 2203, pp. 167-184. Springer 10.1007/978-1-0716-0900-2_13
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Jonsdottir, Hulda R.; Marti, Sabrina; Geerts, Dirk; Rodriguez, Regulo; Thiel, Volker; Dijkman, Ronald (2019). Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions. Viruses, 11(8) Molecular Diversity Preservation International MDPI 10.3390/v11080747
Kratzel, Annika; Thiel, Volker; Pfaender, Stephanie (2019). Zoonotic coronavirus infections. Pipette - Swiss laboratory medicine(4), pp. 18-19. EMH Schweizerischer Ärzteverlag AG
Contu, Lara; Steiner, Silvio; Thiel, Volker; Mühlemann, Oliver (2019). The Role of Stress Granules and the Nonsense-mediated mRNA Decay Pathway in Antiviral Defence. CHIMIA, 73(6), pp. 374-379. Schweizerische Chemische Gesellschaft 10.2533/chimia.2019.374
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V'kovski, Philip; Gerber, Markus; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga Lagache, Sophie; Simillion, Cedric; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (2019). Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling. eLife, 8 eLife Sciences Publications 10.7554/eLife.42037
Alves, Marco; Vielle, Nathalie Jane; Thiel, Volker Earl; Pfänder, Stephanie (2018). Research Models and Tools for the Identification of Antivirals and Therapeutics against Zika Virus Infection. Viruses, 10(11) Molecular Diversity Preservation International MDPI 10.3390/v10110593
Garcia Nicolas, Obdulio; V'kovski, Philip; Vielle, Nathalie J.; Ebert, Nadine; Züst, R; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Vieyres, G; Stoffel, Michael; Schweizer, Matthias; Summerfield, Artur; Engler, O; Pietschmann, T; Todt, D; Alves, Marco; Thiel, Volker; Pfänder, Stephanie (2018). The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor. Antimicrobial agents and chemotherapy, 62(11) American Society for Microbiology 10.1128/AAC.01206-18
Muth, Doreen; Corman, Victor Max; Roth, Hanna; Binger, Tabea; Dijkman, Ronald; Gottula, Lina Theresa; Gloza-Rausch, Florian; Balboni, Andrea; Battilani, Mara; Rihtarič, Danijela; Toplak, Ivan; Ameneiros, Ramón Seage; Pfeifer, Alexander; Thiel, Volker Earl; Drexler, Jan Felix; Müller, Marcel Alexander; Drosten, Christian (2018). Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission. Scientific Reports, 8(1), p. 15177. Nature Publishing Group 10.1038/s41598-018-33487-8
Thiel, Volker Earl (2018). Synthetic viruses-Anything new? PLoS pathogens, 14(10), e1007019. Public Library of Science 10.1371/journal.ppat.1007019
V'kovski, Philip; Gerber, M; Kelly, Jenna Nicole; Pfänder, Stephanie; Ebert, Nadine; Braga, Sophie Marie-Pierre; Simillion, Cedric André Marie; Portmann, Jasmine; Stalder, Hanspeter; Gaschen, Véronique; Bruggmann, Rémy; Stoffel, Michael Hubert; Heller, Manfred; Dijkman, Ronald; Thiel, Volker Earl (14 September 2018). Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling (bioRxiv). Cold Spring Harbor Laboratory 10.1101/417907
Ibrahim, Bashar; McMahon, Dino P; Hufsky, Franziska; Beer, Martin; Deng, Li; Mercier, Philippe Le; Palmarini, Massimo; Thiel, Volker Earl; Marz, Manja (2018). A new era of virus bioinformatics. Virus research, 251, pp. 86-90. Elsevier 10.1016/j.virusres.2018.05.009
Milewska, Aleksandra; Kindler, Eveline Patricia; V'Kovski, Philip; Zeglen, S; Ochman, M; Thiel, Volker Earl; Rajfur, Z; Pyrc, K (2018). APOBEC3-mediated restriction of RNA virus replication. Scientific Reports, 8(1), p. 5960. Nature Publishing Group 10.1038/s41598-018-24448-2
Rappe, Julie Christiane Françoise; de Wilde, Adriaan; Di, Han; Müller, Christin; Stalder, Hanspeter; V'Kovski, Philip; Snijder, Eric; Brinton, Margo A; Ziebuhr, John; Ruggli, Nicolas; Thiel, Volker Earl (2018). Antiviral activity of K22 against members of the order Nidovirales. Virus research, 246, pp. 28-34. Elsevier 10.1016/j.virusres.2018.01.002
Hufsky, Franziska; Ibrahim, Bashar; Beer, Martin; Deng, Li; Mercier, Philippe Le; McMahon, Dino P; Palmarini, Massimo; Thiel, Volker Earl; Marz, Manja (2018). Virologists-Heroes need weapons. PLoS pathogens, 14(2), e1006771. Public Library of Science 10.1371/journal.ppat.1006771
Behrendt, Patrick; Perin, Paula; Menzel, Nicolas; Banda, Dominic; Pfänder, Stephanie; Alves, Marco; Thiel, Volker Earl; Meulemann, Phillip; Colpitts, Che C; Schang, Luis M; Vondran, Florian W R; Anggakusuma, A; Manns, Michael P; Steinmann, Eike; Pietschmann, Thomas (2017). Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral research, 147, pp. 19-28. Elsevier 10.1016/j.antiviral.2017.09.006
Pfänder, Stephanie; Walter, Stephanie; Grabski, Elena; Todt, Daniel; Bruening, Janina; Romero-Brey, Inés; Gather, Theresa; Brown, Richard J P; Hahn, Kerstin; Puff, Christina; Pfankuche, Vanessa M; Hansmann, Florian; Postel, Alexander; Becher, Paul; Thiel, Volker Earl; Kalinke, Ulrich; Wagner, Bettina; Bartenschlager, Ralf; Baumgärtner, Wolfgang; Feige, Karsten; ... (2017). Immune protection against reinfection with nonprimate hepacivirus. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(12), E2430-E2439. National Academy of Sciences NAS 10.1073/pnas.1619380114
Siddharta, Anindya; Pfänder, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker Earl; Steinmann, Eike (2017). Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. Journal of infectious diseases, 215(6), pp. 902-906. Oxford University Press 10.1093/infdis/jix046
Kindler, Eveline Patricia; Gil-Cruz, Cristina; Spanier, Julia; Li, Yize; Wilhelm, Jochen; Rabouw, Huib H; Züst, Roland; Hwang, Mihyun; V'Kovski, Philip; Stalder, Hanspeter; Marti, Sabrina; Habjan, Matthias; Cervantes-Barragan, Luisa; Elliot, Ruth; Karl, Nadja; Gaughan, Christina; van Kuppeveld, Frank J M; Silverman, Robert H; Keller, Markus; Ludewig, Burkhard; ... (2017). Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS pathogens, 13(2), e1006195. Public Library of Science 10.1371/journal.ppat.1006195
Pfänder, Stephanie; Vielle, Nathalie Jane; Ebert, Nadine; Steinmann, E; Alves, Marco; Thiel, Volker Earl (2017). Inactivation of Zika virus in human breast milk by prolonged storage or pasteurization. Virus research, 228, pp. 58-60. Elsevier 10.1016/j.virusres.2016.11.025
Wu, Nai-Huei; Yang, Wei; Beineke, Andreas; Dijkman, Ronald; Matrosovich, Mikhail; Baumgärtner, Wolfgang; Thiel, Volker Earl; Valentin-Weigand, Peter; Meng, Fandan; Herrler, Georg (2016). The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells. Scientific Reports, 6(39668), p. 39668. Nature Publishing Group 10.1038/srep39668
Greub, Gilbert; Holliger, Christof; Sanglard, Dominique; Schrenzel, Jacques; Thiel, Volker; Viollier, Patrick (2016). The Swiss Society of Microbiology: Small Bugs, Big Questions and Cool Answers. CHIMIA, 70(12), pp. 874-877. Schweizerische Chemische Gesellschaft 10.2533/chimia.2016.874
Corman, Victor M; Eckerle, Isabella; Memish, Ziad A; Liljander, Anne M; Dijkman, Ronald; Jonsdottir, Hulda; Juma Ngeiywa, Kisi J Z; Kamau, Esther; Younan, Mario; Al Masri, Malakita; Assiri, Abdullah; Gluecks, Ilona; Musa, Bakri E; Meyer, Benjamin; Müller, Marcel A; Hilali, Mosaad; Bornstein, Set; Wernery, Ulrich; Thiel, Volker; Jores, Jörg; ... (2016). Link of a ubiquitous human coronavirus to dromedary camels. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(35), pp. 9864-9869. National Academy of Sciences NAS 10.1073/pnas.1604472113
Kaderali, Lars; Thiel, Volker Earl (2016). Systems biology of viral infection. Virus research, 218, p. 1. Elsevier 10.1016/j.virusres.2016.05.020
Kindler, Eveline Patricia; Thiel, Volker Earl (2016). SARS-CoV and IFN: Too Little, Too Late. Cell host & microbe, 19(2), pp. 139-141. Cell Press 10.1016/j.chom.2016.01.012
Kindler, Eveline Patricia; Thiel, Volker Earl; Weber, F (2016). Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. Advances in virus research, 96, pp. 219-243. Elsevier 10.1016/bs.aivir.2016.08.006
Corman, Victor Max; Baldwin, Heather J; Tateno, Adriana Fumie; Zerbinati, Rodrigo Melim; Annan, Augustina; Owusu, Michael; Nkrumah, Evans Ewald; Maganga, Gael Darren; Oppong, Samuel; Adu-Sarkodie, Yaw; Vallo, Peter; da Silva Filho, Luiz Vicente Ribeiro Ferreira; Leroy, Eric M; Thiel, Volker Earl; van der Hoek, Lia; Poon, Leo L M; Tschapka, Marco; Drosten, Christian; Drexler, Jan Felix (2015). Evidence for an Ancestral Association of Human Coronavirus 229E with Bats. Journal of virology, 89(23), pp. 11858-11870. American Society for Microbiology 10.1128/JVI.01755-15
Lauber, C; Vieyres, G; Terczyńska-Dyla, E; Anggakusuma, X; Dijkman, Ronald; Gad, H H; Akhtar, H; Geffers, R; Vondran, F W R; Thiel, Volker Earl; Kaderali, L; Pietschmann, T; Hartmann, R (2015). Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. Genes and immunity, 16(6), pp. 414-421. Nature Publishing Group 10.1038/gene.2015.23
Mielech, Anna M; Deng, Xufang; Chen, Yafang; Kindler, Eveline Patricia; Wheeler, Dorthea L; Mesecar, Andrew D; Thiel, Volker Earl; Perlman, Stanley; Baker, Susan C (2015). Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. Journal of virology, 89(9), pp. 4907-4917. American Society for Microbiology 10.1128/JVI.00338-15
V'Kovski, Philip; Al-Mulla, Hawaa; Thiel, Volker Earl; Neuman, Benjamin W (2015). New insights on the role of paired membrane structures in coronavirus replication. Virus research, 202, pp. 33-40. Elsevier 10.1016/j.virusres.2014.12.021
Pas, Suzan D.; Patel, Pranav; Reusken, Chantal; Domingo, Cristina; Corman, Victor M.; Drosten, Christian; Dijkman, Ronald; Thiel, Volker Earl; Nowotny, Norbert; Koopmans, Marion P.G.; Niedrig, Matthias (2015). First international external quality assessment of molecular diagnostics for Mers-CoV. Journal of clinical virology, 69, pp. 81-85. Elsevier 10.1016/j.jcv.2015.05.022
Kindler, E; Thiel, Volker Earl (2014). To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion. Current opinion in microbiology, 20, pp. 69-75. Elsevier 10.1016/j.mib.2014.05.005
Lundin, Anna; Dijkman, Ronald; Bergström, Tomas; Kann, Nina; Adamiak, Beata; Hannoun, Charles; Kindler, Eveline; Jónsdóttir, Hulda R; Muth, Doreen; Kint, Joeri; Forlenza, Maria; Müller, Marcel A; Drosten, Christian; Thiel, Volker Earl; Trybala, Edward (2014). Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS pathogens, 10(5), e1004166. Public Library of Science 10.1371/journal.ppat.1004166
Al-Mulla, Hawaa M N; Turrell, Lauren; Smith, Nicola M; Payne, Luke; Baliji, Surendranath; Züst, Roland; Thiel, Volker Earl; Baker, Susan C; Siddell, Stuart G; Neuman, Benjamin W (2014). Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. mBio, 5(2), e01107-e01113. American Society for Microbiology 10.1128/mBio.01107-13
Thiel, Volker Earl; Thiel, Heinz-Jürgen; Tekes, Gergely (2014). Tackling feline infectious peritonitis via reverse genetics. Bioengineered, 5(6), pp. 396-400. Taylor & Francis 10.4161/bioe.32133
Dijkman, Ronald; Jebbink, Maarten F; Koekkoek, Sylvie M; Deijs, Martin; Jonsdottir, Hulda R.; Molenkamp, Richard; Ieven, Margareta; Goossens, Herman; Thiel, Volker; van der Hoek, Lia (2013). Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism. Journal of virology, 87(11), pp. 6081-6090. American Society for Microbiology 10.1128/JVI.03368-12
Kindler, Eveline; Jonsdottir, Hulda R.; Muth, Doreen; Hamming, Ole J; Hartmann, Rune; Rodriguez, Regulo; Geffers, Robert; Fouchier, Ron A M; Drosten, Christian; Müller, Marcel A; Dijkman, Ronald; Thiel, Volker (2013). Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential. mBio, 4(1), e00611-e00612. American Society for Microbiology 10.1128/mBio.00611-12
