Hemphill, Andrew

Boubaker, Ghalia; Bernal, Alice; Vigneswaran, Anitha; Imhof, Dennis; Ferreira de Sousa, Maria Cristina; Hänggeli, Kai Pascal Alexander; Haudenschild, Noé; Furrer, Julien; Păunescu, Emilia; Desiatkina, Oksana; Hemphill, Andrew (2024). In vitro and in vivo activities of a trithiolato-diRuthenium complex conjugated with sulfadoxine against the apicomplexan parasite Toxoplasma gondii. International journal for parasitology. Drugs and drug resistance, 25(100544), p. 100544. Elsevier 10.1016/j.ijpddr.2024.100544

Ferreira de Sousa, Maria Cristina; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Choi, Ryan; Hulverson, Matthew A; Arnold, Samuel L M; Van Voorhis, Wesley C; Fan, Erkang; Roberto, Sánchez-Sánchez; Ortega-Mora, Luis M; Hemphill, Andrew (2024). Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice. International journal for parasitology. Drugs and drug resistance, 25, p. 100553. Elsevier 10.1016/j.ijpddr.2024.100553

Arthiyan, Sivasingham; Eswaramohan, Thampoe; Hemphill, Andrew; Surendran, Sinnathamby Noble (2024). Predatory Potential of Nymphal Odonates on Aedes aegypti Developing in Freshwater and Brackish Water Habitats. Insects, 15(7) MDPI 10.3390/insects15070547

Müller, Joachim; Boubaker, Ghalia; Müller, Norbert; Uldry, Anne-Christine; Braga-Lagache, Sophie; Heller, Manfred; Hemphill, Andrew (2024). Investigating Antiprotozoal Chemotherapies with Novel Proteomic Tools-Chances and Limitations: A Critical Review. International journal of molecular sciences, 25(13) MDPI 10.3390/ijms25136903

Rubiola, Selene; Moré, Gastón; Civera, Tiziana; Hemphill, Andrew; Frey, Caroline F; Basso, Walter; Colasanto, Irene; Vercellino, Davide; Fidelio, Marta; Lovisone, Mauro; Chiesa, Francesco (2024). Detection of Sarcocystis hominis, Sarcocystis bovifelis, Sarcocystis cruzi, Sarcocystis hirsuta and Sarcocystis sigmoideus sp. nov. in carcasses affected by bovine eosinophilic myositis. Food and waterborne parasitology, 34(e00220) Elsevier 10.1016/j.fawpar.2024.e00220

Ajiboye, Jubilee; Uldry, Anne-Christine; Heller, Manfred; Naguleswaran, Arunasalam; Fan, Erkang; Van Voorhis, Wesley C; Hemphill, Andrew; Müller, Joachim (2024). Molecular Targets of the 5-Amido-Carboxamide Bumped Kinase Inhibitor BKI-1748 in Cryptosporidium parvum and HCT-8 Host Cells. International journal of molecular sciences, 25(5) MDPI 10.3390/ijms25052707

Müller, Joachim; Hemphill, Andrew (2024). In vitro screening technologies for the discovery and development of novel drugs against Toxoplasma gondii. Expert opinion on drug discovery, 19(1), pp. 97-109. Taylor & Francis 10.1080/17460441.2023.2276349

Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Ferreira de Sousa, Maria Cristina; Vigneswaran, Anitha; Hofmann, Larissa; Amdouni, Yosra; Boubaker, Ghalia; Müller, Joachim; Hemphill, Andrew (2024). Working towards the development of vaccines and chemotherapeutics against neosporosis—With all of its ups and downs—Looking ahead. Advances in Parasitology, 124, pp. 91-154. Elsevier 10.1016/bs.apar.2024.01.001

Rico-San Román, Laura; Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Horcajo, Pilar; Collantes-Fernández, Esther; Ortega-Mora, Luis Miguel; Boubaker, Ghalia (2024). TaqMan-quantitative PCR assays applied in Neospora caninum knock-outs generated through CRISPR-Cas9 allow to determine the copy numbers of integrated dihydrofolate reductase-thymidylate synthase drug selectable markers. Frontiers in cellular and infection microbiology, 14(1419209) Frontiers 10.3389/fcimb.2024.1419209

Kaethner, Marc; Rennar, Georg; Gallinger, Tom; Kämpfer, Tobias; Hemphill, Andrew; Mäder, Patrick; Luque-Gómez, Ana; Schlitzer, Martin; Lundström Stadelmann, Britta (2023). In Vitro Activities of Dithiocarbamate Derivatives against Echinococcus multilocularis Metacestode Vesicles. Tropical medicine and infectious disease, 8(12) MDPI 10.3390/tropicalmed8120517

Schlange, Carling; Müller, Joachim; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Boubaker, Ghalia; Ortega-Mora, Luis-Miguel; Wong, Ho Ning; Haynes, Richard K; Van Voorhis, Wesley C; Hemphill, Andrew (2023). Single and combination treatment of Toxoplasma gondii infections with a bumped kinase inhibitor and artemisone in vitro and with artemiside in experimentally infected mice. Experimental parasitology, 255(108655), p. 108655. Elsevier 10.1016/j.exppara.2023.108655

Hemphill, Andrew; Leitão, Alexandre; Ortega-Mora, Luis-Miguel; Cooke, Brian M (2023). ApicoWplexa 2022: 6th international meeting on apicomplexan parasites in farm animals. International journal for parasitology, 53(9), pp. 459-461. Elsevier 10.1016/j.ijpara.2023.05.003

Kaethner, Marc; Preza, Matías; Kaempfer, Tobias; Zumstein, Pascal; Tamponi, Claudia; Varcasia, Antonio; Hemphill, Andrew; Brehm, Klaus; Lundström-Stadelmann, Britta (2023). Establishment and application of unbiased in vitro drug screening assays for the identification of compounds against Echinococcus granulosus sensu stricto. PLoS neglected tropical diseases, 17(8), e0011343. Public Library of Science 10.1371/journal.pntd.0011343

Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Müller, Norbert; Heller, Manfred; Uldry, Anne-Christine; Braga-Lagache, Sophie; Müller, Joachim; Boubaker, Ghalia (2023). Comparative Proteomic Analysis of Toxoplasma gondii RH Wild-Type and Four SRS29B (SAG1) Knock-Out Clones Reveals Significant Differences between Individual Strains. International journal of molecular sciences, 24(13) MDPI 10.3390/ijms241310454

Hemphill, Andrew; Müller, Joachim (2023). Toxoplasma gondii infection: Novel emerging therapeutic targets. Expert opinion on therapeutic targets, 27(4-5), pp. 293-304. Taylor & Francis 10.1080/14728222.2023.2217353

Sivabalakrishnan, Kokila; Thanihaichelvan, Murugathas; Tharsan, Annathurai; Eswaramohan, Thamboe; Ravirajan, Punniamoorthy; Hemphill, Andrew; Ramasamy, Ranjan; Surendran, Sinnathamby N (2023). Resistance to the larvicide temephos and altered egg and larval surfaces characterize salinity-tolerant Aedes aegypti. Scientific Reports, 13(1), p. 8160. Nature Publishing Group 10.1038/s41598-023-35128-1

Müller, Joachim; Schlange, Carling; Heller, Manfred; Uldry, Anne-Christine; Braga-Lagache, Sophie; Haynes, Richard K; Hemphill, Andrew (2023). Proteomic characterization of Toxoplasma gondii ME49 derived strains resistant to the artemisinin derivatives artemiside and artemisone implies potential mode of action independent of ROS formation. International journal for parasitology. Drugs and drug resistance, 21, pp. 1-12. Elsevier 10.1016/j.ijpddr.2022.11.005

Ramseier, Jessica; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Anghel, Nicoleta; Boubaker, Ghalia; Beteck, Richard M; Ortega-Mora, Luis-Miguel; Haynes, Richard K; Hemphill, Andrew (2023). In Vitro versus in Mice: Efficacy and Safety of Decoquinate and Quinoline-O-Carbamate Derivatives against Experimental Infection with Neospora caninum Tachyzoites. Pathogens, 12(3) MDPI AG 10.3390/pathogens12030447

Karimi, Saeid; Bahari, Aliasghar; Nourian, Alireza; Azami, Sakineh; Namavari, Mehdi; Basso, Walter Ubaldo; Sazmand, Alireza; Hemphill, Andrew (2023). Neospora caninum and Toxoplasma gondii infections in one-humped camels (Camelus dromedarius) in central desert of Iran. Parasitology research, 122(3), pp. 847-852. Springer 10.1007/s00436-023-07783-w

Desiatkina, Oksana; Anghel, Nicoleta; Boubaker, Ghalia; Amdouni, Yosra; Hemphill, Andrew; Furrer, Julien; Păunescu, Emilia (2023). Trithiolato-bridged dinuclear ruthenium(II)-arene conjugates tethered with lipophilic units: Synthesis and Toxoplasma gondii antiparasitic activity. Journal of organometallic chemistry, 986, p. 122624. Elsevier 10.1016/j.jorganchem.2023.122624

Khordadmehr, Monireh; Sazmand, Alireza; Almasi, Pardis; Shahbazi, Parisa; Ranjbar, Vahidreza; Otranto, Domenico; Hemphill, Andrew (2023). Natural infection with Toxoplasma gondii, Neospora caninum and Sarcocystis species in domestic pigeons (Columba livia domestica) in Iran. Comparative immunology, microbiology and infectious diseases, 93, p. 101946. Elsevier 10.1016/j.cimid.2023.101946

Holzer, Isabelle; Desiatkina, Oksana; Anghel, Nicoleta; Johns, Serena K; Boubaker, Ghalia; Hemphill, Andrew; Furrer, Julien; Păunescu, Emilia (2023). Synthesis and Antiparasitic Activity of New Trithiolato-Bridged Dinuclear Ruthenium(II)-arene-carbohydrate Conjugates. Molecules, 28(2) MDPI 10.3390/molecules28020902

Imhof, Dennis; Pownall, William; Hänggeli, Kai Pascal Alexander; Monney, Camille; Rico-San Román, Laura; Ortega-Mora, Luis-Miguel; Forterre, Franck; Oevermann, Anna; Hemphill, Andrew (2023). Immunization with a Multivalent Listeria monocytogenes Vaccine Leads to a Strong Reduction in Vertical Transmission and Cerebral Parasite Burden in Pregnant and Non-Pregnant Mice Infected with Neospora caninum. Vaccines, 11(1), p. 156. MDPI 10.3390/vaccines11010156

Kronenberg, Philipp A.; Reinehr, Michael; Eichenberger, Ramon Marc; Hasler, Sina; Laurimäe, Teivi; Weber, Achim; Deibel, Ansgar; Müllhaupt, Beat; Gottstein, Bruno; Müller, Norbert; Hemphill, Andrew; Deplazes, Peter (2023). Monoclonal antibody-based localization of major diagnostic antigens in metacestode tissue, excretory/secretory products, and extracellular vesicles of Echinococcus species (In Press). Frontiers in cellular and infection microbiology, 13 Frontiers 10.3389/fcimb.2023.1162530

Desiatkina, Oksana; Boubaker, Ghalia; Anghel, Nicoleta; Amdouni, Yosra; Hemphill, Andrew; Furrer, Julien; Paunescu, Emilia (2022). Synthesis, Photophysical Properties and Biological Evaluation of New Conjugates BODIPY - Dinuclear Trithiolato-Bridged Ruthenium(II)-Arene Complexes. ChemBioChem, 23(23), e202200536. Wiley 10.1002/cbic.202200536

Ramakrishnan, Chandra; Krishnan, Aarti; Francisco, Samuel; Schmid, Marc W; Russo, Giancarlo; Leitão, Alexandre; Hemphill, Andrew; Soldati-Favre, Dominique; Hehl, Adrian B (2022). Dissection of Besnoitia besnoiti intermediate host life cycle stages: From morphology to gene expression. PLoS pathogens, 18(11), e1010955. Public Library of Science 10.1371/journal.ppat.1010955

Müller, Joachim; Boubaker, Ghalia; Imhof, Dennis; Hänggeli, Kai; Haudenschild, Noé; Uldry, Anne-Christine; Braga-Lagache, Sophie; Heller, Manfred; Ortega-Mora, Luis-Miguel; Hemphill, Andrew (2022). Differential Affinity Chromatography Coupled to Mass Spectrometry: A Suitable Tool to Identify Common Binding Proteins of a Broad-Range Antimicrobial Peptide Derived from Leucinostatin. Biomedicines, 10(11) MDPI 10.3390/biomedicines10112675

Nasuhidehnavi, Azadeh; Zhao, Yanlin; Punetha, Ankita; Hemphill, Andrew; Li, Hong; Bechtel, Tyler J; Rager, Theresa; Xiong, Bingcong; Petrou, Vasileios I; Gubbels, Marc-Jan; Weerapana, Eranthie; Yap, George S (2022). A Role for Basigin in Toxoplasma gondii Infection. Infection and immunity, 90(8), e0020522. American Society for Microbiology 10.1128/iai.00205-22

Imhof, Dennis; Pownall, William Robert; Schlange, Carling; Monney, Camille; Ortega-Mora, Luis-Miguel; Ojo, Kayode K; Van Voorhis, Wesley C; Oevermann, Anna; Hemphill, Andrew (2022). Vaccine-Linked Chemotherapy Approach: Additive Effects of Combining the Listeria monocytogenes-Based Vaccine Lm3Dx_NcSAG1 With the Bumped Kinase Inhibitor BKI-1748 Against Neospora caninum Infection in Mice. Frontiers in veterinary science, 9, p. 901056. Frontiers Media 10.3389/fvets.2022.901056

Zheng, Yang; Müller, Joachim; Kunz, Stefan; Siderius, Marco; Maes, Louis; Caljon, Guy; Müller, Norbert; Hemphill, Andrew; Sterk, Geert Jan; Leurs, Rob (2022). 3-nitroimidazo[1,2-b]pyridazine as a novel scaffold for antiparasitics with sub-nanomolar anti-Giardia lamblia activity. International journal for parasitology. Drugs and drug resistance, 19, pp. 47-55. Elsevier 10.1016/j.ijpddr.2022.05.004

Kuhnert, Peter; Brodard, Isabelle; Bock, Sabine; Hemphill, Andrew; Akarsu Egger, Hatice; Engelhardt, Andreas; Kutzer, Peter (2022). Wielerella bovis gen. nov., sp. nov. a member of the family Neisseriaceae associated with bovine endocarditis. International journal of systematic and evolutionary microbiology, 72(5) Society for General Microbiology SGM 10.1099/ijsem.0.005387

Müller, Joachim; Anghel, Nicoleta; Imhof, Dennis; Hänggeli, Kai; Uldry, Anne-Christine; Braga-Lagache, Sophie; Heller, Manfred; Ojo, Kayode K; Ortega-Mora, Luis-Miguel; Van Voorhis, Wesley C; Hemphill, Andrew (2022). Common Molecular Targets of a Quinolone Based Bumped Kinase Inhibitor in Neospora caninum and Danio rerio. International journal of molecular sciences, 23(4) MDPI 10.3390/ijms23042381

Chaudhry, Sheena; Zurbriggen, Raphael; Preza, Matías; Kämpfer, Tobias; Kaethner, Marc; Memedovski, Roman; Scorrano, Nathalie; Hemphill, Andrew; Doggett, Joseph Stone; Lundström-Stadelmann, Britta (2022). Dual inhibition of the Echinococcus multilocularis energy metabolism. Frontiers in veterinary science, 9, p. 981664. Frontiers Media 10.3389/fvets.2022.981664

Badirzadeh, Alireza; Najm, Mehdi; Hemphill, Andrew; Alipour, Maryam; Hasanpour, Hamid; Masoori, Leila; Karimi, Poorya (2022). Effects of negative air ions (NAIs) on Leishmania major: A novel tool for treatment of zoonotic cutaneous leishmaniasis (ZCL). PLoS ONE, 17(9), e0274124. Public Library of Science 10.1371/journal.pone.0274124

Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Müller, Norbert; Schimanski, Bernd; Olias, Philipp; Müller, Joachim; Boubaker, Ghalia (2022). Single- and duplex TaqMan-quantitative PCR for determining the copy numbers of integrated selection markers during site-specific mutagenesis in Toxoplasma gondii by CRISPR-Cas9. PLoS ONE, 17(9), e0271011. Public Library of Science 10.1371/journal.pone.0271011

Desiatkina, Oksana; Mösching, Martin; Anghel, Nicoleta; Boubaker, Ghalia; Amdouni, Yosra; Hemphill, Andrew; Furrer, Julien; Păunescu, Emilia (2022). New Nucleic Base-Tethered Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Compounds: Synthesis and Antiparasitic Activity. Molecules, 27(23), p. 8173. MDPI 10.3390/molecules27238173

Anghel, Nicoleta; Imhof, Dennis; Winzer, Pablo; Balmer, Vreni; Ramseier, Jessica; Haenggeli, Kai; Choi, Ryan; Hulverson, Matthew A; Whitman, Grant R; Arnold, Samuel L M; Ojo, Kayode K; Van Voorhis, Wesley C; Doggett, J Stone; Ortega-Mora, Luis M; Hemphill, Andrew (2021). Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo. International journal for parasitology. Drugs and drug resistance, 17, pp. 92-106. Elsevier 10.1016/j.ijpddr.2021.08.007

Sánchez-Sánchez, Roberto; Ferre, Ignacio; Re, Michela; Pérez-Arroyo, Bárbara; Cleofé-Resta, Darío; García, Victor Herrero; Díaz, Manuel Pizarro; Ferrer, Luis Miguel; Ruiz, Hector; Vallejo-García, Raquel; Benavides, Julio; Hulverson, Matthew A; Choi, Ryan; Whitman, Grant R; Hemphill, Andrew; Van Voorhis, Wesley C; Ortega-Mora, Luis Miguel (2021). A short-term treatment with BKI-1294 does not protect foetuses from sheep experimentally infected with Neospora caninum tachyzoites during pregnancy. International journal for parasitology. Drugs and drug resistance, 17, pp. 176-185. Elsevier 10.1016/j.ijpddr.2021.10.001

Lightowlers, Marshall W; Gasser, Robin B; Hemphill, Andrew; Romig, Thomas; Tamarozzi, Francesca; Deplazes, Peter; Torgerson, Paul R; Garcia, Hector H; Kern, Peter (2021). Advances in the treatment, diagnosis, control and scientific understanding of taeniid cestode parasite infections over the past 50 years. International journal for parasitology, 51(13-14), pp. 1167-1192. Elsevier 10.1016/j.ijpara.2021.10.003

Imhof, Dennis; Pownall, William Robert; Monney, Camille; Oevermann, Anna; Hemphill, Andrew (2021). A Listeria monocytogenes-Based Vaccine Formulation Reduces Vertical Transmission and Leads to Enhanced Pup Survival in a Pregnant Neosporosis Mouse Model. Vaccines, 9(12) MDPI 10.3390/vaccines9121400

Karpstein, Tanja; Chaudhry, Sheena; Bresson-Hadni, Solange; Hayoz, Michael; Boubaker, Ghalia; Hemphill, Andrew; Rufener, Reto; Kaethner, Marc; Schindler, Isabelle; Aebi, Yolanda; Cunha, Antonio Sa; Largiadèr, Carlo R.; Lundström Stadelmann, Britta (2021). Maca against Echinococcosis?-A Reverse Approach from Patient to In Vitro Testing. Pathogens, 10(10) MDPI AG 10.3390/pathogens10101335

Anghel, Nicoleta; Müller, Joachim; Serricchio, Mauro; Jelk, Jennifer; Bütikofer, Peter; Boubaker, Ghalia; Imhof, Dennis; Ramseier, Jessica; Desiatkina, Oksana; Paunescu, Emilia; Braga, Sophie Marie-Pierre; Heller, Manfred; Furrer, Julien; Hemphill, Andrew (2021). Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei. International journal of molecular sciences, 22(19) MDPI 10.3390/ijms221910787

Hemphill, Andrew; Lundström-Stadelmann, Britta (2021). Echinococcus - the model cestode parasite. Parasitology, 148(12), pp. 1401-1405. Cambridge University Press 10.1017/S003118202100113X

Imhof, Dennis; Anghel, Nicoleta; Winzer, Pablo; Balmer, Vreni; Ramseier, Jessica; Hänggeli, Kai; Choi, Ryan; Hulverson, Matthew A; Whitman, Grant R; Arnold, Samuel L M; Ojo, Kayode K; Van Voorhis, Wesley C; Doggett, J Stone; Ortega-Mora, Luis M; Hemphill, Andrew (2021). In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts. International journal for parasitology. Drugs and drug resistance, 16, pp. 90-101. Elsevier 10.1016/j.ijpddr.2021.05.001

Brand, Michael; Wang, Lei; Agnello, Stefano; Gazzola, Silvia; Gall, Flavio M; Raguž, Luka; Kaiser, Marcel; Schmidt, Remo S; Ritschl, Amélie; Jelk, Jennifer; Hemphill, Andrew; Mäser, Pascal; Bütikofer, Peter; Adams, Michael; Riedl, Rainer (2021). Antiprotozoal Structure-Activity Relationships of Synthetic Leucinostatin Derivatives and Elucidation of their Mode of Action. Angewandte Chemie (International ed.), 60(28), pp. 15613-15621. Wiley-VCH 10.1002/anie.202102153

Păunescu, Emilia; Boubaker, Ghalia; Desiatkina, Oksana; Anghel, Nicoleta; Amdouni, Yosra; Hemphill, Andrew; Furrer, Julien (2021). The Quest of the Best – A SAR Study of Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Compounds Presenting Antiparasitic Properties. European journal of medicinal chemistry, 222, p. 113610. Elsevier Masson SAS 10.1016/j.ejmech.2021.113610

Schönecker, Lutz; Schnydrig, Philipp; Brodard, Isabelle; Thomann, Andreas; Hemphill, Andrew; Rodriguez-Campos, Sabrina; Perreten, Vincent; Jores, Joerg; Kittl, Sonja (2021). Trueperella pecoris sp. nov. isolated from bovine and porcine specimens. International journal of systematic and evolutionary microbiology, 71(6) Society for General Microbiology SGM 10.1099/ijsem.0.004848

Serricchio, Mauro; Hierro-Yap, Carolina; Schädeli, David; Ben Hamidane, Hisham; Hemphill, Andrew; Graumann, Johannes; Zíková, Alena; Bütikofer, Peter (2021). Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms. FASEB journal, 35(2), e21176. Federation of American Societies for Experimental Biology 10.1096/fj.202001579RR

Mohammadi, Mohsen; Dehghani, Parva; Mohseninia, Atefeh; Roozbehani, Mona; Hemphill, Andrew; Hesamizadeh, Khashayar (2021). Incorporation of the Tat cell-penetrating peptide into nanofibers improves the respective antitumor immune response. Journal of cellular physiology, 236(2), pp. 1401-1417. Wiley 10.1002/jcp.29946

Sist, Birgit; Basso, Walter; Hemphill, Andrew; Cassidy, Tamar; Cassidy, Rod; Gudehus, Maja (2021). Case report: Intestinal perforation and secondary peritonitis due to Acanthocephala infection in a black-bellied pangolin (Phataginus tetradactyla). Parasitology international, 80, p. 102182. Elsevier 10.1016/j.parint.2020.102182

Van Voorhis, Wesley C; Hulverson, Matthew A; Choi, Ryan; Huang, Wenlin; Arnold, Samuel L M; Schaefer, Deborah A; Betzer, Dana P; Vidadala, Rama S R; Lee, Sangun; Whitman, Grant R; Barrett, Lynn K; Maly, Dustin J; Riggs, Michael W; Fan, Erkang; Kennedy, Thomas J; Tzipori, Saul; Doggett, J Stone; Winzer, Pablo; Anghel, Nicoleta; Imhof, Dennis; ... (2021). One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases. Veterinary parasitology, 289, p. 109336. Elsevier 10.1016/j.vetpar.2020.109336

Desiatkina, Oksana; Johns, Serena K.; Anghel, Nicoleta; Boubaker, Ghalia; Hemphill, Andrew; Furrer, Julien; Păunescu, Emilia (2021). Synthesis and Antiparasitic Activity of New Conjugates—Organic Drugs Tethered to Trithiolato-Bridged Dinuclear Ruthenium(II)–Arene Complexes. Inorganics, 9(8), p. 59. MDPI 10.3390/inorganics9080059

Pownall, William Robert; Imhof, Dennis; Fernandez Trigo, Nerea; Ganal-Vonarburg, Stephanie C.; Plattet, Philippe; Monney, Camille; Forterre, Franck; Hemphill, Andrew; Oevermann, Anna (2021). Safety of a Novel Listeria monocytogenes-Based Vaccine Vector Expressing NcSAG1 (Neospora caninum Surface Antigen 1). Frontiers in cellular and infection microbiology, 11(675219), p. 675219. Frontiers 10.3389/fcimb.2021.675219

Ramseier, Jessica; Imhof, Dennis; Anghel, Nicoleta; Hänggeli, Kai; Beteck, Richard M.; Balmer, Vreni; Ortega-Mora, Luis-Miguel; Sanchez-Sanchez, Roberto; Ferre, Ignacio; Haynes, Richard K.; Hemphill, Andrew (2021). Assessment of the Activity of Decoquinate and Its Quinoline-O-Carbamate Derivatives against Toxoplasma gondii In Vitro and in Pregnant Mice Infected with T. gondii Oocysts. Molecules, 26(21), p. 6393. MDPI 10.3390/molecules26216393

Vural, G.; Yardimci, M.; Kocak, M.; Yasar, T. Ö.; Kurt, A.; Harem, I. S.; Carradori, S.; Sciamanna, I.; Siles-Lucas, M.; Fabiani, M.; Hemphill, A.; Lundström-Stadelmann, B.; Cirilli, R.; Casulli, A. (2020). Efficacy of novel albendazole salt formulations against secondary cystic echinococcosis in experimentally infected mice. Parasitology, 147(13), pp. 1425-1432. Cambridge University Press 10.1017/s0031182020001225

Desiatkina, Oksana; Păunescu, Emilia; Mösching, Martin; Anghel, Nicoleta; Boubaker, Ghalia; Amdouni, Yosra; Hemphill, Andrew; Furrer, Julien (2020). Coumarin‐Tagged Dinuclear Trithiolato‐Bridged Ruthenium(II)⋅Arene Complexes: Photophysical Properties and Antiparasitic Activity. ChemBioChem, 21(19), pp. 2818-2835. Wiley-VCH 10.1002/cbic.202000174

Anghel, Nicoleta; Winzer, Pablo A.; Imhof, Dennis; Müller, Joachim; Langa, Javier; Rieder, Jessica; Barrett, Lynn K.; Vidadala, Rama Subba Rao; Huang, Wenlin; Choi, Ryan; Hulverson, Mathew A.; Whitman, Grant R.; Arnold, Samuel L.; Van Voorhis, Wesley C.; Ojo, Kayode K.; Maly, Dustin J.; Fan, Erkang; Hemphill, Andrew (2020). Comparative assessment of the effects of bumped kinase inhibitorson early zebrafish embryo development and pregnancy in mice. International journal of antimicrobial agents, 56(3), p. 106099. Elsevier 10.1016/j.ijantimicag.2020.106099

Marcu, Irene C.; Eberhard, Naja; Yerly, Anaïs; Balmer, Verena; Hemphill, Andrew; Mogel, Helga; Gaschen, Véronique; Stoffel, Michael H.; Bluteau, Jasmin (2020). Isolation of Human Small Extracellular Vesicles and Tracking of their Uptake by Retinal Pigment Epithelial Cells In Vitro. International journal of molecular sciences, 21(11), pp. 1-19. MDPI 10.3390/ijms21113799

Winzer, Pablo; Müller, Joachim; Imhof, Dennis; Ritler, Dominic; Uldry, Anne-Christine; Braga-Lagache, Sophie; Heller, Manfred; Ojo, Kayode K; Van Voorhis, Wesley C; Ortega-Mora, Luis-Miguel; Hemphill, Andrew (2020). Neospora caninum: Differential Proteome of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294. Microorganisms, 8(6) MDPI 10.3390/microorganisms8060801

Lin, Yan; Ong, Yih Ching; Keller, Sarah; Karges, Johannes; Bouchene, Rafika; Manoury, Eric; Blacque, Olivier; Müller, Joachim; Anghel, Nicoleta; Hemphill, Andrew; Häberli, Cécile; Taki, Aya C; Gasser, Robin B; Cariou, Kevin; Keiser, Jennifer; Gasser, Gilles (2020). Synthesis, characterization and antiparasitic activity of organometallic derivatives of the anthelmintic drug albendazole. Dalton transactions, 49(20), pp. 6616-6626. Royal Society of Chemistry 10.1039/d0dt01107j

Dawoody Nejad, Ladan; Stumpe, Michael; Rauch, Monika; Hemphill, Andrew; Schneiter, Roger; Bütikofer, Peter; Serricchio, Mauro (2020). Mitochondrial sphingosine-1-phosphate lyase is essential for phosphatidylethanolamine synthesis and survival of Trypanosoma brucei. Scientific reports, 10(1), p. 8268. Springer Nature 10.1038/s41598-020-65248-x

Winzer, Pablo Arnold; Anghel, Nicoleta; Imhof, Dennis; Balmer, Vreni; Ortega-Mora, Luis-Miguel; Ojo, Kayode K; Van Voorhis, Wesley C; Müller, Joachim; Hemphill, Andrew (2020). Neospora caninum: Structure and Fate of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294. Pathogens, 9(5) MDPI AG 10.3390/pathogens9050382

Boubaker, Ghalia; Strempel, Sebastian; Hemphill, Andrew; Müller, Norbert; Wang, Junhua; Gottstein, Bruno; Spiliotis, Markus (2020). Regulation of hepatic microRNAs in response to early stage Echinococcus multilocularis egg infection in C57BL/6 mice. PLoS neglected tropical diseases, 14(5), e0007640. Public Library of Science 10.1371/journal.pntd.0007640

Choi, Ryan; Hulverson, Matthew A; Huang, Wenlin; Vidadala, Rama S R; Whitman, Grant R; Barrett, Lynn K; Schaefer, Deborah A; Betzer, Dana P; Riggs, Michael W; Doggett, J Stone; Hemphill, Andrew; Ortega-Mora, Luis Miguel; McCloskey, Molly C; Arnold, Samuel L M; Hackman, Robert C; Marsh, Kennan C; Lynch, James J; Freiberg, Gail M; Leroy, Bruce E; Kempf, Dale J; ... (2020). Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned. International journal for parasitology, 50(5), pp. 413-422. Elsevier 10.1016/j.ijpara.2020.01.006

Müller, Joachim; Winzer, Pablo A.; Samby, Kirandeep; Hemphill, Andrew (2020). In Vitro Activities of MMV Malaria Box Compounds against the Apicomplexan Parasite Neospora caninum, the Causative Agent of Neosporosis in Animals. Molecules, 25(6) MDPI 10.3390/molecules25061460

Huber, Sandra; Bär, Anina; Epp, Selina; Schmuckli-Maurer, Jacqueline; Eberhard, Naja; Humbel, Bruno M; Hemphill, Andrew; Woods, Kerry (2020). Recruitment of Host Nuclear Pore Components to the Vicinity of Theileria Schizonts. mSphere, 5(1) American Society for Microbiology 10.1128/mSphere.00709-19

Wang, Junhua; Marreros, Nelson; Rufener, Reto; Hemphill, Andrew; Gottstein, Bruno; Lundström-Stadelmann, Britta (2020). Short communication: Efficacy of albendazole in Echinococcus multilocularis-infected mice depends on the functional immunity of the host. Experimental parasitology, 219, p. 108013. Elsevier 10.1016/j.exppara.2020.108013

Lundström-Stadelmann, Britta; Rufener, Reto; Hemphill, Andrew (2020). Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis. International journal for parasitology. Drugs and drug resistance, 13, pp. 121-129. Elsevier 10.1016/j.ijpddr.2020.06.002

Studer, Valentin; Anghel, Nicoleta; Desiatkina, Oksana; Felder, Timo; Boubaker, Ghalia; Amdouni, Yosra; Ramseier, Jessica; Hungerbühler, Martin; Kempf, Christoph; Heverhagen, Johannes Thomas; Hemphill, Andrew; Ruprecht, Nico; Furrer, Julien; Păunescu, Emilia (2020). Conjugates Containing Two and Three Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Units as In Vitro Antiparasitic and Anticancer Agents. Pharmaceuticals, 13(12), p. 471. MDPI 10.3390/ph13120471

Winzer, Pablo; Imhof, Dennis; Anghel, Nicoleta; Ritler, Dominic; Müller, Joachim; Boubaker, Ghalia; Aguado-Martinez, Adriana; Ortega-Mora, Luis-Miguel; Ojo, Kayode K; VanVoorhis, Wesley C; Hemphill, Andrew (2020). The Impact of BKI-1294 Therapy in Mice Infected With the Apicomplexan Parasite Neospora caninum and Re-infected During Pregnancy. Frontiers in veterinary science, 7, p. 587570. Frontiers Media 10.3389/fvets.2020.587570

Eberhard, Naja; Balmer, Vreni; Müller, Joachim; Müller, Norbert; Winter, Rolf; Pou, Soviti; Nilsen, Aaron; Riscoe, Mike; Francisco, Samuel; Leitao, Alexandre; Doggett, J Stone; Hemphill, Andrew (2020). Activities of Endochin-Like Quinolones Against in vitro Cultured Besnoitia besnoiti Tachyzoites. Frontiers in veterinary science, 7, p. 96. Frontiers Media 10.3389/fvets.2020.00096

Silva, Marta Filipa; Pereira, Gonçalo; Carneiro, Carla; Hemphill, Andrew; Mateus, Luísa; Lopes-da-Costa, Luís; Silva, Elisabete (2020). Campylobacter portucalensis sp. nov., a new species of Campylobacter isolated from the preputial mucosa of bulls. PLoS ONE, 15(1), e0227500. Public Library of Science 10.1371/journal.pone.0227500

Schädeli, David Lukas; Serricchio, Mauro; Ben Hamidane, Hisham; Loffreda, Alessio; Hemphill, Andrew; Beneke, Tom; Gluenz, Eva; Graumann, Johannes; Bütikofer, Peter (2019). Cardiolipin depletion-induced changes in the Trypanosoma brucei proteome. FASEB journal, 33(12), pp. 13161-13175. Federation of American Societies for Experimental Biology 10.1096/fj.201901184RR

Jelk, Jennifer; Balmer, Vreni; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Bütikofer, Peter; Furrer, Julien; Hemphill, Andrew (2019). Anti-parasitic dinuclear thiolato-bridged arene ruthenium complexes alter the mitochondrial ultrastructure and membrane potential in Trypanosoma brucei bloodstream forms. Experimental parasitology, 205, p. 107753. Elsevier 10.1016/j.exppara.2019.107753

Shrestha, Aruna; Ojo, Kayode K; Koston, Florian; Ruttkowski, Bärbel; Vidadala, Rama S R; Dorr, Carlie S; Navaluna, Edelmar D; Whitman, Grant R; Barrett, Kayleigh F; Barrett, Lynn K; Hulverson, Matthew A; Choi, Ryan; Michaels, Samantha A; Maly, Dustin J; Hemphill, Andrew; Van Voorhis, Wesley C; Joachim, Anja (2019). Bumped kinase inhibitor 1369 is effective against Cystoisospora suis in vivo and in vitro. International journal for parasitology. Drugs and drug resistance, 10, pp. 9-19. Elsevier 10.1016/j.ijpddr.2019.03.004

Hemphill, Andrew; Müller, Norbert; Müller, Joachim (2019). Comparative Pathobiology of the Intestinal Protozoan Parasites Giardia lamblia, Entamoeba histolytica, and Cryptosporidium parvum. Pathogens, 8(3) MDPI AG 10.3390/pathogens8030116

Sánchez-Sánchez, Roberto; Ferre, Ignacio; Re, Michela; Ramos, Juan José; Regidor-Cerrillo, Javier; Pizarro Díaz, Manuel; González-Huecas, Marta; Tabanera, Enrique; Benavides, Julio; Hemphill, Andrew; Hulverson, Matthew A; Barrett, Lynn K; Choi, Ryan; Whitman, Grant R; Ojo, Kayode K; Van Voorhis, Wesley C; Ortega-Mora, Luis Miguel (2019). Treatment with Bumped Kinase Inhibitor 1294 Is Safe and Leads to Significant Protection against Abortion and Vertical Transmission in Sheep Experimentally Infected with Toxoplasma gondii during Pregnancy. Antimicrobial agents and chemotherapy, 63(7) American Society for Microbiology 10.1128/AAC.02527-18

Hizem, Amani; Lundström-Stadelmann, Britta; M'rad, Selim; Souiai, Sawssen; Ben Jannet, Hichem; Flamini, Guido; Ascrizzi, Roberta; Ghedira, Kamel; Babba, Hamouda; Hemphill, Andrew (2019). Activity of Thymus capitatus essential oil components against in vitro cultured Echinococcus multilocularis metacestodes and germinal layer cells. Parasitology, 146(7), pp. 956-967. Cambridge University Press 10.1017/S0031182019000295

Lundström-Stadelmann, Britta; Rufener, Reto; Ritler, Dominic; Zurbriggen, Raphael Peter; Hemphill, Andrew (2019). The importance of being parasiticidal… an update on drug development for the treatment of alveolar echinococcosis. Food and waterborne parasitology, 15, e00040. Elsevier 10.1016/j.fawpar.2019.e00040

Silva Pinto Basto, Afonso; Anghel, Nicoleta; Rubbiani, Riccardo; Müller, Joachim; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Balmer, Vreni; Gasser, Gilles; Furrer, Julien; Hemphill, Andrew (2019). Targeting of the mitochondrion by dinuclear thiolato-bridged arene ruthenium complexes in cancer cells and in the apicomplexan parasite Neospora caninum. Metallomics, 11(2), pp. 462-474. Royal Society of Chemistry 10.1039/C8MT00307F

García-Lunar, P; Schares, G; Sanz-Fernández, A; Jiménez-Meléndez, A; García-Soto, I; Regidor-Cerrillo, J; Pastor-Fernández, I; Hemphill, Andrew; Fernández-Álvarez, M; Ortega-Mora, L M; Álvarez-García, G (2019). Development and characterization of monoclonal antibodies against Besnoitia besnoiti tachyzoites. Parasitology, 146(2), pp. 187-196. Cambridge University Press 10.1017/S0031182018001336

Aguado Martinez, Adriana; Basto, Afonso P; Tanaka, Shun; Ryser, Lorenz T; Nunes, Telmo P; Ortega-Mora, Luis-Miguel; Arranz-Solís, David; Leitão, Alexandre; Hemphill, Andrew (2019). Immunization with a cocktail of antigens fused with OprI reduces Neospora caninum vertical transmission and postnatal mortality in mice. Vaccine, 37(3), pp. 473-483. Elsevier 10.1016/j.vaccine.2018.11.060

Sánchez-Sánchez, Roberto; Ferre, Ignacio; Regidor-Cerrillo, Javier; Gutiérrez-Expósito, Daniel; Ferrer, Luis Miguel; Arteche-Villasol, Noive; Moreno-Gonzalo, Javier; Müller, Joachim; Aguado Martinez, Adriana; Pérez, Valentín; Hemphill, Andrew; Ortega-Mora, Luis Miguel; Benavides, Julio (2019). Virulence in Mice of a Toxoplasma gondii Type II Isolate Does Not Correlate With the Outcome of Experimental Infection in Pregnant Sheep. Frontiers in cellular and infection microbiology, 8(436), p. 436. Frontiers 10.3389/fcimb.2018.00436

Müller, Joachim; Manser, Vera; Hemphill, Andrew (2019). In vitro treatment of Besnoitia besnoiti with the naphto-quinone buparvaquone results in marked inhibition of tachyzoite proliferation, mitochondrial alterations and rapid adaptation of tachyzoites to increased drug concentrations. Parasitology, 146(1), pp. 112-120. Cambridge University Press 10.1017/S0031182018000975

Masoori, Leila; Meamar, Ahmad Reza; Bandehpour, Mojgan; Hemphill, Andrew; Razmjou, Elham; Mokhtarian, Kobra; Roozbehani, Mona; Badirzadeh, Alireza; Jalallou, Nahid; Akhlaghi, Lame; Falak, Reza (2019). Fatty acid and retinol-binding protein: A novel antigen for immunodiagnosis of human strongyloidiasis. PLoS ONE, 14(7), e0218895. Public Library of Science 10.1371/journal.pone.0218895

Hemphill, Andrew; Rufener, Reto; Ritler, Dominic; Dick, Luca; Lundström Stadelmann, Britta (2019). Drug Discovery and Development for the Treatment of Echinococcosis, Caused by the Tapeworms Echinococcus granulosus and Echinococcus multilocularis. In: Swinney, David C.; Pollastri, Michael P. (eds.) Neglected Tropical Diseases: drug discovery and development. Methods and Principles in Medicinal Chemistry (pp. 253-287). Wiley 10.1002/9783527808656.ch10

Anghel, Nicoleta; Balmer, Vreni; Müller, Joachim; Winzer, Pablo Arnold; Aguado Martinez, Adriana; Roozbehani, Mona; Pou, Sovitj; Nilsen, Aaron; Riscoe, Michael; Doggett, J Stone; Hemphill, Andrew (2018). Endochin-Like Quinolones Exhibit Promising Efficacy Against Neospora Caninum in vitro and in Experimentally Infected Pregnant Mice. Frontiers in veterinary science, 5, p. 285. Frontiers Media 10.3389/fvets.2018.00285

Roozbehani, Mona; Falak, Reza; Mohammadi, Mohsen; Hemphill, Andrew; Razmjou, Elham; Meamar, Ahmad Reza; Masoori, Leila; Khoshmirsafa, Majid; Moradi, Maryam; Gharavi, Mohammad Javad (2018). Characterization of a multi-epitope peptide with selective MHC-binding capabilities encapsulated in PLGA nanoparticles as a novel vaccine candidate against Toxoplasma gondii infection. Vaccine, 36(41), pp. 6124-6132. Elsevier 10.1016/j.vaccine.2018.08.068

Jiménez-Meléndez, Alejandro; Rico-San Román, Laura; Hemphill, Andrew; Balmer, Vreni; Ortega-Mora, Luis Miguel; Álvarez-García, Gema (2018). Repurposing of commercially available anti-coccidials identifies diclazuril and decoquinate as potential therapeutic candidates against Besnoitia besnoiti infection. Veterinary parasitology, 261, pp. 77-85. Elsevier 10.1016/j.vetpar.2018.08.015

Olias, Philipp Alexander; Dettwiler, Ines Sarah; Hemphill, Andrew; Deplazes, P; Steiner, Adrian; Meylan, Mireille (2018). [The significance of cryptosporidiosis for the health of calves in Switzerland]. Schweizer Archiv für Tierheilkunde, 160(6), pp. 363-374. Gesellschaft Schweizer Tierärztinnen und Tierärzte 10.17236/sat00163

Joekel, Deborah E.; Lundström-Stadelmann, Britta; Müllhaupt, Beat; Hemphill, Andrew; Deplazes, Peter (2018). Evaluation of kinase-inhibitors nilotinib and everolimus against alveolar echinococcosis in vitro and in a mouse model. Experimental parasitology, 188, pp. 65-72. Elsevier 10.1016/j.exppara.2018.04.002

Dawoody Nejad, Ladan; Serricchio, Mauro; Jelk, Jennifer; Hemphill, Andrew; Bütikofer, Peter (2018). TbLpn, a key enzyme in lipid droplet formation and phospholipid metabolism, is essential for mitochondrial integrity and growth of Trypanosoma brucei. Molecular microbiology, 109(1), pp. 105-120. Wiley 10.1111/mmi.13976

Sánchez-Sánchez, Roberto; Ferre, Ignacio; Re, Michela; Vázquez, Patricia; Ferrer, Luis Miguel; Blanco-Murcia, Javier; Regidor-Cerrillo, Javier; Pizarro Díaz, Manuel; González-Huecas, Marta; Tabanera, Enrique; García-Lunar, Paula; Benavides, Julio; Castaño, Pablo; Hemphill, Andrew; Hulverson, Matthew A; Whitman, Grant R; Rivas, Kasey L; Choi, Ryan; Ojo, Kayode K; Barrett, Lynn K; ... (2018). Safety and efficacy of the bumped kinase inhibitor BKI-1553 in pregnant sheep experimentally infected with Neospora caninum tachyzoites. International journal for parasitology. Drugs and drug resistance, 8(1), pp. 112-124. Elsevier 10.1016/j.ijpddr.2018.02.003

De Amorim Cardoso, Rita Isabel; Wang, Junhua; Müller, Joachim; Rupp, Sebastian Dominic Alexander; Leitão, Alexandre; Hemphill, Andrew (2018). Modulation of cis- and trans- Golgi and the Rab9A-GTPase during infection by Besnoitia besnoiti, Toxoplasma gondii and Neospora caninum. Experimental parasitology, 187, pp. 75-85. Elsevier 10.1016/j.exppara.2018.02.008

Rufener, Reto; Dick, Luca; D'Ascoli, Laura; Ritler, Dominic; Hizem, Amani; Wells, Timothy N.C.; Hemphill, Andrew; Lundström-Stadelmann, Britta (2018). Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis. International journal for parasitology. Drugs and drug resistance, 8(3), pp. 440-450. Elsevier 10.1016/j.ijpddr.2018.10.011

Rufener, Reto; Ritler, Dominic; Zielinski, Jana; Dick, Luca; da Silva, Emerson Teixeira; da Silva Araujo, Adriele; Joekel, Deborah Elisabeth; Czock, David; Göpfert, Christine; Moraes, Adriana Marques; de Souza, Marcus Vinicius Nora; Müller, Joachim; Mevissen, Meike; Hemphill, Andrew; Lundström-Stadelmann, Britta (2018). Activity of mefloquine and mefloquine derivatives against Echinococcus multilocularis. International journal for parasitology. Drugs and drug resistance, 8(2), pp. 331-340. Elsevier 10.1016/j.ijpddr.2018.06.004

Müller, Joachim; Hemphill, Andrew; Müller, Norbert (2018). Physiological aspects of nitro drug resistance in Giardia lamblia. International journal for parasitology. Drugs and drug resistance, 8(2), pp. 271-277. Elsevier 10.1016/j.ijpddr.2018.04.008

Harmse, Rozanne; Wong, Ho Ning; Smit, Frans J; Müller, Joachim; Hemphill, Andrew; N'Da, David D; Haynes, Richard K (2017). Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Neospora caninum and Comparative Cytotoxicities. ChemMedChem, 12(24), pp. 2094-2098. Wiley-VCH 10.1002/cmdc.201700600

Hemphill, Andrew; Leitão, Alexandre; Ortega-Mora, Luis-Miguel; Cooke, Brian M (2017). ApiCOWplexa 2017 - 4th International Meeting on Apicomplexan Parasites in Farm Animals. International journal for parasitology, 47(12), pp. 697-699. Elsevier 10.1016/j.ijpara.2017.09.002

Aguado Martinez, Adriana; Basto, Afonso P; Leitão, Alexandre; Hemphill, Andrew (2017). Neospora caninum in non-pregnant and pregnant mouse models: cross-talk between infection and immunity. International journal for parasitology, 47(12), pp. 723-735. Elsevier 10.1016/j.ijpara.2017.09.001

Jiménez-Meléndez, Alejandro; Ojo, Kayode K; Wallace, Alexandra M; Smith, Tess R; Hemphill, Andrew; Balmer, Vreni; Regidor-Cerrillo, Javier; Ortega-Mora, Luis M; Hehl, Adrian B; Fan, Erkang; Maly, Dustin J; Van Voorhis, Wesley C; Álvarez-García, Gema (2017). In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites. International journal for parasitology, 47(12), pp. 811-821. Elsevier 10.1016/j.ijpara.2017.08.005

Hulverson, Matthew A; Choi, Ryan; Arnold, Samuel L M; Schaefer, Deborah A; Hemphill, Andrew; McCloskey, Molly C; Betzer, Dana P; Müller, Joachim; Vidadala, Rama S R; Whitman, Grant R; Rivas, Kasey L; Barrett, Lynn K; Hackman, Robert C; Love, Melissa S; McNamara, Case W; Shaughnessy, Thomas K; Kondratiuk, Alison; Kurnick, Matthew; Banfor, Patricia N; Lynch, James J; ... (2017). Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis. International journal for parasitology, 47(12), pp. 753-763. Elsevier 10.1016/j.ijpara.2017.08.006

Müller, Joachim; Aguado Martinez, Adriana; Laleu, Benoît; Balmer, Vreni; Ritler, Dominic; Hemphill, Andrew (2017). In vitro screening of the open source Pathogen Box identifies novel compounds with profound activities against Neospora caninum. International journal for parasitology, 47(12), pp. 801-809. Elsevier 10.1016/j.ijpara.2017.06.002

Van Voorhis, Wesley C; Doggett, J Stone; Parsons, Marilyn; Hulverson, Matthew A; Choi, Ryan; Arnold, Samuel; Riggs, Michael W; Hemphill, Andrew; Howe, Daniel K; Mealey, Robert H; Lau, Audrey O T; Merritt, Ethan A; Maly, Dustin J; Fan, Erkang; Ojo, Kayode K (2017). Extended-spectrum antiprotozoal bumped kinase inhibitors: A review. Experimental parasitology, 180, pp. 71-83. Elsevier 10.1016/j.exppara.2017.01.001

Kunz, Stefan; Balmer, Vreni; Sterk, Geert Jan; Pollastri, Michael P; Leurs, Rob; Müller, Norbert; Hemphill, Andrew; Spycher, Cornelia (2017). The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target. PLoS neglected tropical diseases, 11(9), e0005891. Public Library of Science 10.1371/journal.pntd.0005891

Müller, Joachim; Aguado Martinez, Adriana; Ortega-Mora, Luis-Miguel; Moreno-Gonzalo, Javier; Ferre, Ignacio; Hulverson, Matthew A; Choi, Ryan; McCloskey, Molly C; Barrett, Lynn K; Maly, Dustin J; Ojo, Kayode K; Van Voorhis, Wes; Hemphill, Andrew (2017). Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis. Journal of antimicrobial chemotherapy, 72(8), pp. 2334-2341. Oxford University Press 10.1093/jac/dkx134

Silva Pinto Basto, Afonso; Müller, Joachim; Rubbiani, Riccardo; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Balmer, Vreni; Hemphill, Andrew; Gasser, Gilles; Furrer, Julien (2017). Characterization of the Activities of Dinuclear Thiolato-Bridged Arene Ruthenium Complexes against Toxoplasma gondii. Antimicrobial agents and chemotherapy, 61(9), e01031-17. American Society for Microbiology 10.1128/AAC.01031-17

Müller, Joachim; Aguado Martinez, Adriana; Balmer, Vreni; Maly, Dustin J; Fan, Erkang; Ortega-Mora, Luis-Miguel; Ojo, Kayode K; Van Voorhis, Wesley C; Hemphill, Andrew (2017). Two novel calcium-dependent kinase 1-inhibitors interfere with vertical transmission in mice infected with Neospora caninum tachyzoites. Antimicrobial agents and chemotherapy, 61(4) American Society for Microbiology 10.1128/AAC.02324-16

Ruppen, Corinne; Hemphill, Andrew; Sendi, Parham (2017). In vitro activity of gentamicin as an adjunct to penicillin against biofilm group B Streptococcus. Journal of antimicrobial chemotherapy, 72(2), pp. 444-447. Oxford University Press 10.1093/jac/dkw447

Ritler, Dominic; Rufener, Reto; Sager, Heinz; Bouvier, Jacques; Hemphill, Andrew; Lundström-Stadelmann, Britta (2017). Development of a movement-based in vitro screening assay for the identification of new anti-cestodal compounds. PLoS neglected tropical diseases, 11(5), e0005618. Public Library of Science 10.1371/journal.pntd.0005618

Gorgas, Daniela; Marreros Canales, Nelson Antonio; Rufener, Reto; Hemphill, Andrew; Lundström-Stadelmann, Britta (2017). To see or not to see: non-invasive imaging for improved readout of drug treatment trials in the murine model of secondary alveolar echinococcosis. Parasitology, 144(07), pp. 937-944. Cambridge University Press 10.1017/S0031182017000051

Leineweber, Margret; Spekker-Bosker, Katrin; Ince, Vanessa; Schares, Gereon; Hemphill, Andrew; Eller, Silvia K; Däubener, Walter (2017). First Characterization of the Neospora caninum Dense Granule Protein GRA9. BioMed research international, 2017, p. 6746437. Hindawi Publishing Corporation 10.1155/2017/6746437

Dubey, Jitender; Hemphill, Andrew; Calero-Bernal, Rafael; Schares, Gereon (2017). Neosporosis in animals [Textbook] . Boca Raton, FL: CRC Press

Horcajo, P; Regidor-Cerrillo, J; Aguado Martinez, Adriana; Hemphill, Andrew; Ortega-Mora, L M (2016). Vaccines for bovine neosporosis: current status and key aspects for development. Parasite immunology, 38(12), pp. 709-723. Wiley 10.1111/pim.12342

Silva, Luciana Damacena; Arrúa, Eva Carolina; Pereira, Dayanne Amaral; Fraga, Carolina Miguel; Costa, Tatiane Luiza da; Hemphill, Andrew; Salomon, Claudio Javier; Vinaud, Marina Clare (2016). Elucidating the influence of praziquantel nanosuspensions on the in vivo metabolism of Taenia crassiceps cysticerci. Acta tropica, 161, pp. 100-105. Elsevier 10.1016/j.actatropica.2016.06.002

Müller, Joachim; Hemphill, Andrew (2016). Drug target identification in protozoan parasites. Expert opinion on drug discovery, 11(8), pp. 815-824. Taylor & Francis 10.1080/17460441.2016.1195945

Van Voorhis, Wesley C; Adams, John H; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H; Alano, Pietro; Alday, Aintzane; Alemán Resto, Yesmalie; Alsibaee, Aishah; Alzualde, Ainhoa; Andrews, Katherine T; Avery, Simon V; Avery, Vicky M; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; ... (2016). Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLoS pathogens, 12(7), e1005763. Public Library of Science 10.1371/journal.ppat.1005763

De Amorim Cardoso, Rita Isabel; Soares, Helena; Hemphill, Andrew; Leitão, Alexandre (2016). Apicomplexans pulling the strings: manipulation of the host cell cytoskeleton dynamics. Parasitology, 143(8), pp. 957-970. Cambridge University Press 10.1017/S0031182016000524

Pastor-Fernández, Iván; Regidor-Cerrillo, Javier; Álvarez-García, Gema; Marugán-Hernández, Virginia; García-Lunar, Paula; Hemphill, Andrew; Ortega-Mora, Luis M (2016). The tandemly repeated NTPase (NTPDase) from Neospora caninum is a canonical dense granule protein whose RNA expression, protein secretion and phosphorylation coincides with the tachyzoite egress. Parasites & Vectors, 9(1), p. 352. BioMed Central 10.1186/s13071-016-1620-4

Hostettler, Isabel; Müller, Joachim; Hemphill, Andrew (2016). In Vitro Screening of the Open-Source Medicines for Malaria Venture Malaria Box Reveals Novel Compounds with Profound Activities against Theileria annulata Schizonts. Antimicrobial agents and chemotherapy, 60(6), pp. 3301-3308. American Society for Microbiology 10.1128/AAC.02801-15

Imhof, Simon; Fragoso, Cristina; Hemphill, Andrew; Von Schubert, Conrad; Li, Dong; Legant, Wesley; Betzig, Erik; Roditi, Isabel (2016). Flagellar membrane fusion and protein exchange in trypanosomes; a new form of cell-cell communication? F1000Research, 5(682), p. 682. F1000 Research Ltd 10.12688/f1000research.8249.1

Aguado Martinez, Adriana; Silva Pinto Basto, Afonso; Müller, Joachim; Balmer, Vreni; Manser, Vera; Leitão, Alexandre; Hemphill, Andrew (2016). N-terminal fusion of a toll-like receptor 2-ligand to a Neospora caninum chimeric antigen efficiently modifies the properties of the specific immune response. Parasitology, 143(5), pp. 606-616. Cambridge University Press 10.1017/S0031182016000056

Lundström-Stadelmann, Britta; Rufener, Reto; Aeschbacher, Denise; Spiliotis, Markus; Gottstein, Bruno; Hemphill, Andrew (2016). Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis. PLoS neglected tropical diseases, 10(3), e0004535. Public Library of Science 10.1371/journal.pntd.0004535

Hemphill, Andrew; Aguado Martinez, Adriana; Müller, Joachim (2016). Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models. Parasitology, 143(3), pp. 245-259. Cambridge University Press 10.1017/S0031182015001596

Pastor-Fernández, Iván; Regidor-Cerrillo, Javier; Jiménez-Ruiz, Elena; Álvarez-García, Gema; Marugán-Hernández, Virginia; Hemphill, Andrew; Ortega-Mora, Luis M (2016). Characterization of the Neospora caninum NcROP40 and NcROP2Fam-1 rhoptry proteins during the tachyzoite lytic cycle. Parasitology, 143(1), pp. 97-113. Cambridge University Press 10.1017/S0031182015001511

Arranz-Solis, David; Benavides, Julio; Regidor-Cerrillo, Javier; Horcajo, Pilar; Castaño, Pablo; del Carmen Ferreras, María; Jiménez-Pelayo, Laura; Collantes-Fernández, Esther; Ferre, Ignacio; Hemphill, Andrew; Pérez, Valentín; Ortega-Mora, Luis Miguel (2016). Systemic and local immune responses in sheep after Neospora caninum experimental infection at early, mid and late gestation. Veterinary research, 47, p. 2. BioMed Central 10.1186/s13567-015-0290-0

Müller, Joachim; Aguado Martinez, Adriana; Manser, Vera; Wong, Ho Ning; Haynes, Richard K; Hemphill, Andrew (2016). Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model. Veterinary research, 47, p. 32. BioMed Central 10.1186/s13567-016-0317-1

Fadda, Angela; Bärtschi, Michelle; Hemphill, Andrew; Widmer, Hans Rudolf; Zurbriggen, Andreas; Perona, P; Vidondo Curras, Beatriz; Oevermann, Anna (2016). Primary Postnatal Dorsal Root Ganglion Culture from Conventionally Slaughtered Calves. PLoS ONE, 11(12), e0168228. Public Library of Science 10.1371/journal.pone.0168228

Küster, Tatiana; Lundström-Stadelmann, Britta; Rufener, Reto; Risch, Corina; Müller, Joachim; Hemphill, Andrew (2015). Oral treatments of Echinococcus multilocularis-infected mice with the antimalarial drug mefloquine that potentially interacts with parasite ferritin and cystatin. International journal of antimicrobial agents, 46(5), pp. 546-551. Elsevier 10.1016/j.ijantimicag.2015.07.016

Gottstein, Bruno; Wang, Junhua; Boubaker, Ghalia; Marinova, Irina; Spiliotis, Markus; Müller, Norbert; Hemphill, Andrew (2015). Susceptibility versus resistance in alveolar echinococcosis (larval infection with Echinococcus multilocularis). Veterinary parasitology, 213(3-4), pp. 103-109. Elsevier 10.1016/j.vetpar.2015.07.029

Winzer, Pablo Arnold; Müller, Joachim; Aguado Martinez, Adriana; Rahman, Mahbubur; Balmer, Vreni; Manser, Vera; Ortega-Mora, Luis Miguel; Ojo, Kayode K; Fan, Erkang; Maly, Dustin J; Van Voorhis, Wesley C; Hemphill, Andrew (2015). In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninum. Antimicrobial agents and chemotherapy, 59(10), pp. 6361-6374. American Society for Microbiology 10.1128/AAC.01236-15

Arranz Solis, David; Aguado Martinez, Adriana; Müller, Joachim; Regidor-Cerrillo, Javier; Ortega-Mora, Luis Miguel; Hemphill, Andrew (2015). Dose-dependent effects of experimental infection with the virulent Neospora caninum Nc-Spain7 isolate in a pregnant mouse model. Veterinary parasitology, 211(3-4), pp. 133-140. Elsevier 10.1016/j.vetpar.2015.05.021

Müller, Joachim; Balmer, Vreni; Winzer, Pablo Arnold; Rahman, Mahbubur; Manser, Vera; Haynes, Richard K; Hemphill, Andrew (2015). In vitro effects of new artemisinin derivatives in Neospora caninum-infected human fibroblasts. International journal of antimicrobial agents, 46(1), pp. 88-93. Elsevier 10.1016/j.ijantimicag.2015.02.020

Boubaker, Ghalia; Hemphill, Andrew; Huber, Cristina Olivia; Spiliotis, Markus; Babba, Hamouda; Gottstein, Bruno (2015). Prevention and Immunotherapy of Secondary Murine Alveolar Echinococcosis Employing Recombinant EmP29 Antigen. PLoS neglected tropical diseases, 9(6), e0003795. Public Library of Science 10.1371/journal.pntd.0003795

Wang, Junhua; Vuitton, Dominique A; Müller, Norbert; Hemphill, Andrew; Spiliotis, Markus; Blagosklonov, Oleg; Grandgirard, Denis; Leib, Stephen; Shalev, Itay; Levy, Gary; Lu, Xiaomei; Lin, Renyong; Wen, Hao; Gottstein, Bruno (2015). Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice. PLoS neglected tropical diseases, 9(5), e0003755. Public Library of Science 10.1371/journal.pntd.0003755

Müller, Joachim; Aguado Martinez, Adriana; Manser, Vera; Balmer, Vreni; Winzer, Pablo Arnold; Ritler, Dominic; Hostettler, Isabel; Arranz Solis, David; Ortega-Mora, Luis; Hemphill, Andrew (2015). Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice. International journal for parasitology. Drugs and drug resistance, 5(1), pp. 16-25. Elsevier 10.1016/j.ijpddr.2015.02.001

Reichel, Michael P; Moore, Dadín P; Hemphill, Andrew; Ortega-Mora, Luis M; Dubey, J P; Ellis, John T (2015). A live vaccine against Neospora caninum abortions in cattle. Vaccine, 33(11), pp. 1299-1301. Elsevier 10.1016/j.vaccine.2015.01.064

Arranz Solis, David; Benavides, Julio; Regidor-Cerrillo, Javier; Fuertes, Miguel; Ferre, Ignacio; Ferreras, Maria Del Carmen; Collantes-Fernández, Esther; Hemphill, Andrew; Pérez, Valentín; Ortega-Mora, Luis Miguel (2015). Influence of the gestational stage on the clinical course, lesional development and parasite distribution in experimental ovine neosporosis. Veterinary research, 46, p. 19. Editions scientifiques Elsevier 10.1186/s13567-014-0139-y

Pastor-Fernández, Iván; Arranz-Solís, David; Regidor-Cerrillo, Javier; Álvarez-García, Gema; Hemphill, Andrew; García-Culebras, Alicia; Cuevas-Martín, Carmen; Ortega-Mora, Luis M (2015). A vaccine formulation combining rhoptry proteins NcROP40 and NcROP2 improves pup survival in a pregnant mouse model of neosporosis. Veterinary parasitology, 207(3-4), pp. 203-215. Elsevier 10.1016/j.vetpar.2014.12.009

Naguleswaran, Arunasalam; Gunasekera, Kapila; Schimanski, Bernd; Heller, Manfred; Hemphill, Andrew; Ochsenreiter, Torsten; Roditi, Isabel (2015). Trypanosoma brucei RRM1 is a nuclear RNA-binding protein and modulator of chromatin structure. mBio, 6(2), e00114. American Society for Microbiology 10.1128/mBio.00114-15

Hostettler, Isabel; Müller, Joachim; Stephens, Chad E; Haynes, Richard; Hemphill, Andrew (2014). A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts. International journal for parasitology. Drugs and drug resistance, 4(3), pp. 201-209. Elsevier 10.1016/j.ijpddr.2014.09.003

Lundström-Stadelmann, Britta; Aeschbacher, Denise; Huber, Cristina; Spiliotis, Markus; Müller, Joachim; Hemphill, Andrew (2014). Profound activity of the anti-cancer drug bortezomib against Echinococcus multilocularis metacestodes identifies the proteasome as a novel drug target for cestodes. PLoS neglected tropical diseases, 8(12), e3352. Public Library of Science 10.1371/journal.pntd.0003352

Boubaker, Ghalia; Gottstein, Bruno; Hemphill, Andrew; Babba, Hamouda; Spiliotis, Markus (2014). Echinococcus P29 antigen: molecular characterization and implication on post-surgery follow-up of CE patients infected with different species of the Echinococcus granulosus complex. PLoS ONE, 9(5), e98357. Public Library of Science 10.1371/journal.pone.0098357

Monney, Thierry; Hemphill, Andrew (2014). Vaccines against neosporosis: what can we learn from the past studies? Experimental parasitology, 140, pp. 52-70. Elsevier 10.1016/j.exppara.2014.02.015

Küster, Tatiana; Lundström-Stadelmann, Britta; Aeschbacher, Denise; Hemphill, Andrew (2014). Activities of fenbendazole in comparison with albendazole against Echinococcus multilocularis metacestodes in vitro and in a murine infection model. International journal of antimicrobial agents, 43(4), pp. 335-342. Elsevier 10.1016/j.ijantimicag.2014.01.013

Küster, Tatiana; Kriegel, Nadja; Lundström-Stadelmann, Britta; Wang, Xiaofang; Dong, Yuxiang; Vennerstrom, Jonathan L; Keiser, Jennifer; Hemphill, Andrew (2014). Amino ozonides exhibit in vitro activity against Echinococcus multilocularis metacestodes. International journal of antimicrobial agents, 43(1), pp. 40-46. Elsevier 10.1016/j.ijantimicag.2013.09.012

Hemphill, Andrew; Lundström-Stadelmann, Britta; Rufener, Reto; Spiliotis, Markus; Boubaker, Ghalia; Müller, Joachim; Müller, Norbert; Gorgas, Daniela; Gottstein, Bruno (2014). Treatment of echinococcosis: albendazole and mebendazole - what else? Parasite, 21, p. 70. Princeps Editions 10.1051/parasite/2014073

Cortes, Helder; Leitão, Alexandre; Gottstein, Bruno; Hemphill, Andrew (2014). A review on bovine besnoitiosis: a disease with economic impact in herd health management, caused by Besnoitia besnoiti (Franco and Borges, 1916). Parasitology, 141(11), pp. 1406-1417. Cambridge University Press 10.1017/S0031182014000262

Hemphill, Andrew; Leitão, Alexandre (2014). ApiCOWplexa 2013--2nd International Meeting on Apicomplexan Parasites in Farm Animals. Parasitology, 141(11), pp. 1355-1358. Cambridge University Press 10.1017/S0031182014001164

Ojo, Kayode K; Reid, Molly C; Kallur Siddaramaiah, Latha; Müller, Joachim; Winzer, Pablo Arnold; Zhang, Zhongsheng; Keyloun, Katelyn R; Vidadala, Rama Subba Rao; Merritt, Ethan A; Hol, Wim G J; Maly, Dustin J; Fan, Erkang; Van Voorhis, Wesley C; Hemphill, Andrew (2014). Neospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapy. PLoS ONE, 9(3), e92929. Public Library of Science 10.1371/journal.pone.0092929

Hemer, Sarah; Konrad, Christian; Spiliotis, Markus; Koziol, Uriel; Schaack, Dominik; Förster, Sabine; Gelmedin, Verena; Lundström-Stadelmann, Britta; Dandekar, Thomas; Hemphill, Andrew; Brehm, Klaus (2014). Host insulin stimulates Echinococcus multilocularis insulin signalling pathways and larval development. BMC biology, 12, p. 5. BioMed Central 10.1186/1741-7007-12-5

Barna, Fabienne; Debache, Karim; Vock, Carsten A.; Küster, Tatiana; Hemphill, Andrew (2013). In vitro effects of novel ruthenium complexes in Neospora caninum and Toxoplasma gondii tachyzoites. Antimicrobial agents and chemotherapy, 57(11), pp. 5747-5754. American Society for Microbiology 10.1128/AAC.02446-12

Küster, Tatiana; Kriegel, Nadja; Boykin, David W.; Stephens, Chad E.; Hemphill, Andrew (2013). In vitro and in vivo activities of dicationic diguanidino compounds against Echinococcus multilocularis metacestodes. Antimicrobial agents and chemotherapy, 57(8), pp. 3829-3835. American Society for Microbiology 10.1128/AAC.02569-12

Spekker, K.; Leineweber, M.; Degrandi, D.; Ince, V.; Brunder, S.; Schmidt, S. K.; Stuhlsatz, S.; Howard, J. C.; Schares, G.; Degistirici, O.; Meisel, R.; Sorg, R. V.; Seissler, J.; Hemphill, Andrew; Pfeffer, K.; Däubener, W. (2013). Antimicrobial effects of murine mesenchymal stromal cells directed against Toxoplasma gondii and Neospora caninum: role of immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs). Medical microbiology and immunology, 202(3), pp. 197-206. Springer 10.1007/s00430-012-0281-y

Hemphill, Andrew; Debache, Karim; Monney, Thierry; Schorer, Michelle; Gouinaud, Christophe; Alaeddine, Ferial; Müller, Norbert; Müller, Joachim (2013). Proteins mediating the Neospora caninum-host cell interaction as targets for vaccination. Frontiers in Bioscience (Elite Edition), 5(1), pp. 23-36. Frontiers in Bioscience

Debache, Karim; Hemphill, Andrew (2013). Differential effects of intranasal vaccination with recombinant NcPDI in different mouse models of Neospora caninum infection. Parasite immunology, 35(1), pp. 11-20. Blackwell Scientific Publications 10.1111/pim.12013

Alaeddine, Ferial; Hemphill, Andrew; Debache, Karim; Guionaud, Christophe (2013). Molecular cloning and characterization of NcROP2Fam-1, a member of the ROP2 family of rhoptry proteins in Neospora caninum that is targeted by antibodies neutralizing host cell invasion in vitro. Parasitology, 140(8), pp. 1033-1050. Cambridge University Press 10.1017/S0031182013000383

Küster, Tatiana; Hermann, Corina; Hemphill, Andrew; Gottstein, Bruno; Spiliotis, Markus (2013). Subcutaneous infection model facilitates treatment assessment of secondary Alveolar echinococcosis in mice. PLoS neglected tropical diseases, 7(5), e2235. Public Library of Science 10.1371/journal.pntd.0002235

Mols-Vorstermans, Tanja; Hemphill, Andrew; Monney, Thierry; Schaap, Dick; Boerhout, Eveline (2013). Differential Effects on Survival, Humoral Immune Responses and Brain Lesions in Inbred BALB/C, CBA/CA, and C57BL/6 Mice Experimentally Infected with Neospora caninum Tachyzoites. ISRN Parasitology, 2013, pp. 1-11. Hindawi 10.5402/2013/830980

Monney, Thierry; Grandgirard, Denis; Leib, Stephen; Hemphill, Andrew (2013). Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model. Pathogens, 2(2), pp. 193-208. MDPI AG 10.3390/pathogens2020193

Hemphill, Andrew; Müller, Norbert; Müller, Joachim (2013). Thiazolides, a Novel Class of Anti-Infective Drugs, Effective Against Viruses, Bacteria, Intracellular and Extracellular Protozoan Parasites and Proliferating Mammalian Cells. Anti-infective agents in medicinal chemistry, 11(1), pp. 22-30. Bentham Science 10.2174/22113626130103

Soeiro, M. N. C.; Werbovetz, K.; Boykin, D. W.; Wilson, W. D.; Wang, M. Z.; Hemphill, Andrew (2013). Novel amidines and analogues as promising agents against intracellular parasites: a systematic review. Parasitology, 140(8), pp. 929-951. Cambridge University Press 10.1017/S0031182013000292

Zysset-Burri, Denise Corinne; Gottstein, Bruno; Zumkehr, Béatrice; Hemphill, Andrew; Schürch, Nadia; Wittwer, Matthias; Müller, Norbert (2012). Development of a high- versus low-pathogenicity model of the free-living amoeba Naegleria fowleri. Microbiology, 158(Pt 10), pp. 2652-2660. Society for General Microbiology 10.1099/mic.0.059790-0

Küster, Tatiana; Zumkehr, Beatrice; Hermann, Corina; Theurillat, Regula; Thormann, Wolfgang; Gottstein, Bruno; Hemphill, Andrew (2012). Voluntary ingestion of antiparasitic drugs emulsified in honey represents an alternative to gavage in mice. American Association for Laboratory Animal Science Journal, 51(2), pp. 219-223. American Association for Laboratory Animal Science

Sidler, D; Brockmann, A; Mueller, J; Nachbur, U; Corazza, N; Renzulli, P; Hemphill, A; Brunner, T (2012). Thiazolide-induced apoptosis in colorectal cancer cells is mediated via the Jun kinase-Bim axis and reveals glutathione-S-transferase P1 as Achilles' heel. Oncogene, 31(37), pp. 4095-106. Basingstoke, UK: Nature Publishing Group 10.1038/onc.2011.575

Kropf, C; Debache, K; Rampa, C; Barna, F; Schorer, M; Stephens, C E; Ismail, M A; Boykin, D W; Hemphill, A (2012). The adaptive potential of a survival artist: characterization of the in vitro interactions of Toxoplasma gondii tachyzoites with di-cationic compounds in human fibroblast cell cultures. Parasitology, 139(2), pp. 208-20. London: Cambridge University Press 10.1017/S0031182011001776

Monney, Thierry; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew (2012). Vaccination with the recombinant chimeric antigen recNcMIC3-1-R induces a non-protective Th2-type immune response in the pregnant mouse model for N. caninum infection. Vaccine, 30(46), pp. 6588-94. Amsterdam: Elsevier 10.1016/j.vaccine.2012.08.024

Debache, Karim; Hemphill, Andrew (2012). Effects of miltefosine treatment in fibroblast cell cultures and in mice experimentally infected with Neospora caninum tachyzoites. Parasitology, 139(7), pp. 934-944. Cambridge University Press 10.1017/S0031182012000066

Monney, Thierry; Rütti, David; Schorer, Michelle; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew (2011). RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection. Vaccine, 29(40), pp. 6967-6975. Amsterdam: Elsevier 10.1016/j.vaccine.2011.07.038

Cortes, H.C.; Muller, N.; Boykin, D.; Stephens, C.E.; Hemphill, A. (2011). In vitro effects of arylimidamides against Besnoitia besnoiti infection in Vero cells. Parasitology, 138(5), pp. 583-92. London: Cambridge University Press 10.1017/S0031182011000114

Debache, K.; Guionaud, C.; Kropf, C.; Boykin, D.; Stephens, C.E.; Hemphill, A. (2011). Experimental treatment of Neospora caninum-infected mice with the arylimidamide DB750 and the thiazolide nitazoxanide. Experimental parasitology, 129(2), pp. 95-100. Amsterdam: Elsevier 10.1016/j.exppara.2011.07.010

Debache, K.; Kropf, C.; Schutz, C.A.; Harwood, L.J.; Kauper, P.; Monney, T.; Rossi, N.; Laue, C.; McCullough, K.C.; Hemphill, A. (2011). Vaccination of mice with chitosan nanogel-associated recombinant NcPDI against challenge infection with Neospora caninum tachyzoites. Parasite immunology, 33(2), pp. 81-94. Oxford: Blackwell Scientific Publications 10.1111/j.1365-3024.2010.01255.x

Kuster, T.; Lundström-Stadelmann, Britta; Hermann, C.; Scholl, S.; Keiser, J.; Hemphill, A. (2011). In vitro and in vivo efficacies of mefloquine-based treatment against alveolar echinococcosis. Antimicrobial agents and chemotherapy, 55(2), pp. 713-21. Washington, D.C.: American Society for Microbiology 10.1128/AAC.01392-10

Marcelino, E.; Martins, T.M.; Morais, J.B.; Nolasco, S.; Cortes, H.; Hemphill, A.; Leitao, A.; Novo, C. (2011). Besnoitia besnoiti protein disulfide isomerase (BbPDI): molecular characterization, expression and in silico modelling. Experimental parasitology, 129(2), pp. 164-74. Amsterdam: Elsevier 10.1016/j.exppara.2011.06.012

Marugan-Hernandez, V.; Alvarez-Garcia, G.; Tomley, F.; Hemphill, A.; Regidor-Cerrillo, J.; Ortega-Mora, L.M. (2011). Identification of novel rhoptry proteins in Neospora caninum by LC/MS-MS analysis of subcellular fractions. Journal of proteomics, 74(5), pp. 629-42. Amsterdam: Elsevier 10.1016/j.jprot.2011.02.004

Mejri, N.; Muller, N.; Hemphill, A.; Gottstein, B. (2011). Intraperitoneal Echinococcus multilocularis infection in mice modulates peritoneal CD4+ and CD8+ regulatory T cell development. Parasitology international, 60(1), pp. 45-53. Amsterdam: Elsevier 10.1016/j.parint.2010.10.002

Monney, Thierry; Debache, Karim; Hemphill, Andrew (2011). Vaccines against a major cause of abortion in cattle, Neospora caninum infection. Animals, 1(3), pp. 306-325. Cambridge: MDPI 10.3390/ani1030306

Müller, J.; Müller, N.; Hemphill, A. (2011). Drugs and drug targets in Neospora caninum and related apicomplexans. In: Becker, Katja (ed.) Apicomplexan Parasites. Drug discovery in Infectious Diseases: Vol. 2 (pp. 359-371). Chichester: John Wiley & Sons

Müller, J.; Hemphill, A.; Müller, N. (2011). Treatment of giardiasis and drug resistance. In: Lujan, Hugo D.; Svärd, Staffan (eds.) Giardia - a model organism. Heidelberg: Springer Verlag

Muller, J.; Hemphill, A. (2011). Identification of a host cell target for the thiazolide class of broad-spectrum anti-parasitic drugs. Experimental parasitology, 128(2), pp. 145-50. Amsterdam: Elsevier 10.1016/j.exppara.2011.02.007

Muller, J.; Hemphill, A. (2011). Drug target identification in intracellular and extracellular protozoan parasites. Current topics in medicinal chemistry, 11(16), pp. 2029-38. Hilversum: Bentham Science Publishers 10.2174/156802611796575876

Pohle, S.; Ernst, R.; MacKenzie, C.; Spicher, M.; Romig, T.; Hemphill, A.; Gripp, S. (2011). Echinococcus multilocularis: the impact of ionizing radiation on metacestodes. Experimental parasitology, 127(1), pp. 127-34. Amsterdam: Elsevier 10.1016/j.exppara.2010.07.006

Lundström-Stadelmann, Britta; Kuster, T.; Scholl, S.; Barna, F.; Kropf, C.; Keiser, J.; Boykin, D.W.; Stephens, C.E.; Hemphill, A. (2011). In vitro efficacy of dicationic compounds and mefloquine enantiomers against Echinococcus multilocularis metacestodes. Antimicrobial agents and chemotherapy, 55(10), pp. 4866-72. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00478-11

Pachlatko, E.; Rusch, S.; Müller, A.; Hemphill, A.; Tilley, L.; Hanssen, E.; Beck, H.P. (2010). MAHRP2, an exported protein of Plasmodium falciparum, is an essential component of Maurer's cleft tethers. Molecular microbiology, 77(5), pp. 1136-1152. Oxford: Blackwell Science 10.1111/j.1365-2958.2010.07278.x

Debache, K.; Guionaud, C.; Alaeddine, F.; Hemphill, A. (2010). Intraperitoneal and intra-nasal vaccination of mice with three distinct recombinant Neospora caninum antigens results in differential effects with regard to protection against experimental challenge with Neospora caninum tachyzoites. Parasitology, 137(2), pp. 229-40. London: Cambridge University Press 10.1017/S0031182009991259

Guionaud, C.; Hemphill, A.; Mevissen, M.; Alaeddine, F. (2010). Molecular characterization of Neospora caninum MAG1, a dense granule protein secreted into the parasitophorous vacuole, and associated with the cyst wall and the cyst matrix. Parasitology, 137(11), pp. 1605-19. London: Cambridge University Press 10.1017/S0031182010000442

Hemphill, A. (2010). Development and applications of cestode and trematode laboratory models. Parasitology, 137(3), pp. 329-33. London: Cambridge University Press 10.1017/S0031182010000132

Hemphill, A.; Stadelmann, B.; Scholl, S.; Muller, J.; Spiliotis, M.; Muller, N.; Gottstein, B.; Siles-Lucas, M. (2010). Echinococcus metacestodes as laboratory models for the screening of drugs against cestodes and trematodes. Parasitology, 137(3), pp. 569-87. London: Cambridge University Press 10.1017/S003118200999117X

Mejri, N.; Hemphill, A.; Gottstein, B. (2010). Triggering and modulation of the host-parasite interplay by Echinococcus multilocularis: a review. Parasitology, 137(3), pp. 557-68. London: Cambridge University Press 10.1017/S0031182009991533

Lundström-Stadelmann, Britta; Scholl, Sabrina; Muller, J.; Hemphill, A. (2010). Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes. Journal of antimicrobial chemotherapy, 65(3), pp. 512-9. Oxford: Oxford University Press 10.1093/jac/dkp490

Stadelmann, B.; Spiliotis, M.; Muller, J.; Scholl, S.; Muller, N.; Gottstein, B.; Hemphill, A. (2010). Echinococcus multilocularis phosphoglucose isomerase (EmPGI): a glycolytic enzyme involved in metacestode growth and parasite-host cell interactions. International journal for parasitology, 40(13), pp. 1563-74. Kidlington, UK: Elsevier 10.1016/j.ijpara.2010.05.009

Vassella, Erik; Oberle, Michael; Urwyler, Simon; Renggli, Christina Kunz; Studer, Erwin; Hemphill, Andrew; Fragoso, Cristina; Bütikofer, Peter; Brun, Reto; Roditi, Isabel (2009). Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission by tsetse. PLoS ONE, 4(2), e4493. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0004493

Debache, Karim; Alaeddine, Ferial; Guionaud, Christophe; Monney, Thierry; Müller, Joachim; Strohbusch, Maria; Leib, Stephen L.; Grandgirard, Denis; Hemphill, Andrew (2009). Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites. International journal for parasitology, 39(12), pp. 1373-1384. Kidlington, UK: Elsevier 10.1016/j.ijpara.2009.04.006

Frey, Caroline; Schild, Marc; Hemphill, Andrew; Stünzi, Philipp; Müller, Norbert; Gottstein, Bruno; Burgener, Iwan (2009). Intestinal Tritrichomonas foetus infection in cats in Switzerland detected by in vitro cultivation and PCR. Parasitology research, 104(4), pp. 783-8. Berlin: Springer-Verlag 10.1007/s00436-008-1255-2

Hemphill, Andrew; Vonlaufen, Nathalie; Golaz, Julia L; Burgener, Iwan (2009). Infection of primary canine duodenal epithelial cell cultures with Neospora caninum. Journal of parasitology, 95(2), pp. 372-80. Lawrence, Kans.: American Society of Parasitologists 10.1645/GE-1812.1

Gris, P.; Tighe, A.; Thawer, S.; Hemphill, A.; Oatway, M.; Weaver, L.; Dekaban, G.A.; Brown, A. (2009). Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats. Journal of neuroimmunology, 209(1-2), pp. 104-13. Amsterdam: Elsevier 10.1016/j.jneuroim.2009.02.002

Hemphill, A.; Muller, J. (2009). Alveolar and cystic echinococcosis: towards novel chemotherapeutical treatment options. Journal of helminthology, 83(2), pp. 99-111. Cambridge: Cambridge University Press 10.1017/S0022149X0928936X

Hemphill, A.W.; Akkari, Y.; Newell, A.H.; Schultz, R.A.; Grompe, M.; North, P.S.; Hickson, I.D.; Jakobs, P.M.; Rennie, S.; Pauw, D.; Hejna, J.; Olson, S.B.; Moses, R.E. (2009). Topo IIIalpha and BLM act within the Fanconi anemia pathway in response to DNA-crosslinking agents. Cytogenetic and genome research, 125(3), pp. 165-75. Basel: Karger 10.1159/000230001

Muller, J.; Limban, C.; Stadelmann, B.; Missir, A.V.; Chirita, I.C.; Chifiriuc, M.C.; Nitulescu, G.M.; Hemphill, A. (2009). Thioureides of 2-(phenoxymethyl)benzoic acid 4-R substituted: a novel class of anti-parasitic compounds. Parasitology international, 58(2), pp. 128-35. Amsterdam: Elsevier 10.1016/j.parint.2008.12.003

Müller, Joachim; Nillius, Dorothea; Hehl, A.; Hemphill, Andrew; Müller, Norbert (2009). Stable expression of Escherichia coli beta-glucuronidase A (GusA) in Giardia lamblia: application to high-throughput drug susceptibility testing. Journal of antimicrobial chemotherapy, 64(6), pp. 1187-1191. Oxford: Oxford University Press 10.1093/jac/dkp363

Schnyder, M.; Kohler, L.; Hemphill, A.; Deplazes, P. (2009). Prophylactic and therapeutic efficacy of nitazoxanide against Cryptosporidium parvum in experimentally challenged neonatal calves. Veterinary parasitology, 160(1-2), pp. 149-54. Amsterdam: Elsevier 10.1016/j.vetpar.2008.10.094

Strohbusch, M.; Muller, N.; Hemphill, A.; Krebber, R.; Greif, G.; Gottstein, B. (2009). Toltrazuril treatment of congenitally acquired Neospora caninum infection in newborn mice. Parasitology research, 104(6), pp. 1335-43. Berlin: Springer-Verlag 10.1007/s00436-009-1328-x

Strohbusch, M.; Muller, N.; Hemphill, A.; Margos, M.; Grandgirard, D.; Leib, Stephen; Greif, G.; Gottstein, B. (2009). Neospora caninum and bone marrow-derived dendritic cells: parasite survival, proliferation, and induction of cytokine expression. Parasite immunology, 31(7), pp. 366-372. Oxford: Blackwell Scientific Publications 10.1111/j.1365-3024.2009.01112.x

Gottstein, Bruno; Hemphill, Andrew (2008). Echinococcus multilocularis: the parasite-host interplay. Experimental parasitology, 119(4), pp. 447-452. Elsevier 10.1016/j.exppara.2008.03.002

Spicher, Martin; Naguleswaran, Arunasalam; Ortega-Mora, Luis M; Müller, Joachim; Gottstein, Bruno; Hemphill, Andrew (2008). In vitro and in vivo effects of 2-methoxyestradiol, either alone or combined with albendazole, against Echinococcus metacestodes. Experimental parasitology, 119(4), pp. 475-482. Elsevier 10.1016/j.exppara.2008.02.012

Müller, Joachim; Naguleswaran, Arunasalam; Müller, Norbert; Hemphill, Andrew (2008). Neospora caninum: functional inhibition of protein disulfide isomerase by the broad-spectrum anti-parasitic drug nitazoxanide and other thiazolides. Experimental parasitology, 118(1), pp. 80-8. Amsterdam: Elsevier 10.1016/j.exppara.2007.06.008

Spicher, Martin; Röthlisberger, Carole; Lany, C.; Lundström-Stadelmann, Britta; Keiser, J.; Ortega-Mora, L. M.; Gottstein, Bruno; Hemphill, Andrew (2008). In Vitro and In Vivo Treatments of Echinococcus Protoscoleces and Metacestodes with Artemisinin and Artemisinin Derivatives. Antimicrobial agents and chemotherapy, 52(9), pp. 3447-3450. American Society for Microbiology 10.1128/AAC.00553-08

Müller, Joachim; Ley, Serej; Felger, Ingrid; Hemphill, Andrew; Müller, Norbert (2008). Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole. Journal of antimicrobial chemotherapy, 62(1), pp. 72-82. Oxford University Press 10.1093/jac/dkn142

Strohbusch, Maria; Müller, Norbert; Hemphill, Andrew; , ; Gottstein, Bruno (2008). NcGRA2 as a molecular target to assess the parasiticidal activity of toltrazuril against Neospora caninum. Parasitology, 135(9), pp. 1065-1073. Cambridge University Press 10.1017/S0031182008004599

Oberholzer, Michael; Marti, Gabriela; Baresic, Mario; Kunz, Stefan; Hemphill, Andrew; Seebeck, Thomas (2007). The Trypanosoma brucei cAMP phosphodiesterases TbrPDEB1 and TbrPDEB2: flagellar enzymes that are essential for parasite virulence. FASEB journal, 21(3), pp. 720-731. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.06-6818com

Esposito, Marco; Müller, Norbert; Hemphill, Andrew (2007). Structure-activity relationships from in vitro efficacies of the thiazolide series against the intracellular apicomplexan protozoan Neospora caninum. International journal for parasitology, 37(2), pp. 183-90. Kidlington, UK: Elsevier 10.1016/j.ijpara.2006.10.009

Hemphill, A (2007). Response to Innes and Mattsson: Neospora caninum emerges from the shadow of Toxoplasma gondii. Trends in parasitology, 2(23), pp. 44-5. Oxford: Elsevier Current Trends 10.1016/j.pt.2006.12.007

Sterk, Maaike; Müller, Joachim; Hemphill, Andrew; Müller, Norbert (2007). Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formononetin. Microbiology, 153(Pt 12), pp. 4150-8. Reading, UK: Society for General Microbiology 10.1099/mic.0.2007/010041-0

Arsenijevic, D; de Bilbao, F; Vallet, P; Hemphill, A; Gottstein, B; Richard, D; Giannakopoulos, P; Langhans, W (2007). Decreased infarct size after focal cerebral ischemia in mice chronically infected with Toxoplasma gondii. Neuroscience, 150(3), pp. 537-46. Oxford: Elsevier 10.1016/j.neuroscience.2007.09.080

Hemphill, Andrew; Spicher, Martin; Lundström-Stadelmann, Britta; Müller, Joachim; Naguleswaran, Arunasalam; Gottstein, Bruno; Walker, M (2007). Innovative chemotherapeutical treatment options for alveolar and cystic echinococcosis. Parasitology, 134(Pt 12), pp. 1657-70. London: Cambridge University Press 10.1017/S0031182007003198

Golaz, Julia L; Vonlaufen, Nathalie; Hemphill, Andrew; Burgener, Iwan A (2007). Establishment and characterization of a primary canine duodenal epithelial cell culture. In vitro cellular & developmental biology - animal, 43(5-6), pp. 176-85. Columbia, Md.: Springer-Verlag 10.1007/s11626-007-9034-4

Kaiser, Marcel; Wittlin, Sergio; Nehrbass-Stuedli, Angela; Dong, Yuxiang; Wang, Xiaofang; Hemphill, Andrew; Matile, Hugues; Brun, Reto; Vennerstrom, Jonathan L (2007). Peroxide bond-dependent antiplasmodial specificity of artemisinin and OZ277 (RBx11160). Antimicrobial agents and chemotherapy, 51(8), pp. 2991-3. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00225-07

Müller, Joachim; Sterk, Maaike; Hemphill, Andrew; Müller, Norbert (2007). Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole. Journal of antimicrobial chemotherapy, 60(2), pp. 280-7. Oxford: Oxford University Press 10.1093/jac/dkm205

Esposito, Marco; Moores, Shelley; Naguleswaran, Arunasalam; Müller, Joachim; Hemphill, Andrew (2007). Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs. International journal for parasitology, 37(10), pp. 1143-52. Kidlington, UK: Elsevier 10.1016/j.ijpara.2007.03.007

Müller, Joachim; Wastling, Jonathan; Sanderson, Sanya; Müller, Norbert; Hemphill, Andrew (2007). A novel Giardia lamblia nitroreductase, GlNR1, interacts with nitazoxanide and other thiazolides. Antimicrobial agents and chemotherapy, 51(6), pp. 1979-86. Washington, D.C.: American Society for Microbiology 10.1128/AAC.01548-06

Cortes, Helder C E; Reis, Yara; Gottstein, Bruno; Hemphill, Andrew; Leitão, Alexandre; Müller, Norbert (2007). Application of conventional and real-time fluorescent ITS1 rDNA PCR for detection of Besnoitia besnoiti infections in bovine skin biopsies. Veterinary parasitology, 146(3-4), pp. 352-6. Amsterdam: Elsevier 10.1016/j.vetpar.2007.03.003

Risco-Castillo, V; Fernández-García, A; Zaballos, A; Aguado-Martínez, A; Hemphill, A; Rodríguez-Bertos, A; Alvarez-García, G; Ortega-Mora, L M (2007). Molecular characterisation of BSR4, a novel bradyzoite-specific gene from Neospora caninum. International journal for parasitology, 37(8-9), pp. 887-96. Kidlington, UK: Elsevier 10.1016/j.ijpara.2007.02.003

Cortes, H C E; Mueller, N; Esposito, M; Leitão, A; Naguleswaran, A; Hemphill, A (2007). In vitro efficacy of nitro- and bromo-thiazolyl-salicylamide compounds (thiazolides) against Besnoitia besnoiti infection in Vero cells. Parasitology, 134(Pt 7), pp. 975-85. London: Cambridge University Press 10.1017/S0031182007002417

Vonlaufen, N; Naguleswaran, A; Gianinazzi, C; Hemphill, A (2007). Characterization of the fetuin-binding fraction of Neospora caninum tachyzoites and its potential involvement in host-parasite interactions. Parasitology, 134(Pt 6), pp. 805-17. London: Cambridge University Press 10.1017/S0031182006002186

Srinivasan, Sangeetha; Mueller, Joachim; Suana, Angela; Hemphill, Andrew (2007). Vaccination with microneme protein NcMIC4 increases mortality in mice inoculated with Neospora caninum. Journal of parasitology, 93(5), pp. 1046-55. Lawrence, Kans.: American Society of Parasitologists 10.1645/GE-1181R1.1

Hemphill, A; Müller, N; Müller, J (2007). Structure-funktion relationship of thiazolides, a novel class of antiparasitic drugs, investigated in intracellular protozoan parasites and larvalstage cestodes. Anti-infective agents in medicinal chemistry(6), pp. 273-282. Sharjah: Bentham Science

Hemphill, A (2007). Generation of parasite cysts in cultured cells instead of living animals. ALTEX - Alternativen zu Tierexperimenten, 24(Spec. Issue), pp. 29-31. London: Spektrum Akademischer Verlag

Naguleswaran, Arunasalam; Spicher, Martin; Vonlaufen, Nathalie; Ortega-Mora, Luis M; Torgerson, Paul; Gottstein, Bruno; Hemphill, Andrew (2006). In vitro metacestodicidal activities of genistein and other isoflavones against Echinococcus multilocularis and Echinococcus granulosus. Antimicrobial agents and chemotherapy, 50(11), pp. 3770-8. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00578-06

Matsumoto, J; Müller, N; Hemphill, A; Oku, Y; Kamiya, M; Gottstein, B (2006). 14-3-3- and II/3-10-gene expression as molecular markers to address viability and growth activity of Echinococcus multilocularis metacestodes. Parasitology, 132(Pt 1), pp. 83-94. London: Cambridge University Press 10.1017/S0031182005008632

Srinivasan, Sangeetha; Baszler, Timothy; Vonlaufen, Nathalie; Leepin, Angela; Sanderson, Sanya J; Wastling, Jonathan M; Hemphill, Andrew (2006). Monoclonal antibody directed against Neospora caninum tachyzoite carbohydrate epitope reacts specifically with apical complex-associated sialylated beta tubulin. Journal of parasitology, 92(6), pp. 1235-43. Lawrence, Kans.: American Society of Parasitologists 10.1645/GE-889R.1

Cortes, H C E; Reis, Y; Waap, H; Vidal, R; Soares, H; Marques, I; Pereira da Fonseca, I; Fazendeiro, I; Ferreira, M L; Caeiro, V; Shkap, V; Hemphill, A; Leitão, A (2006). Isolation of Besnoitia besnoiti from infected cattle in Portugal. Veterinary parasitology, 141(3-4), pp. 226-33. Amsterdam: Elsevier 10.1016/j.vetpar.2006.05.022

Müller, Joachim; Rühle, Géraldine; Müller, Norbert; Rossignol, Jean-François; Hemphill, Andrew (2006). In vitro effects of thiazolides on Giardia lamblia WB clone C6 cultured axenically and in coculture with Caco2 cells. Antimicrobial agents and chemotherapy, 50(1), pp. 162-70. Washington, D.C.: American Society for Microbiology 10.1128/AAC.50.1.162-170.2006

Gottstein, Bruno; Haag, Karen; Walker, Mirjam; Matsumoto, Jun; Mejri, Naceur; Hemphill, Andrew (2006). Molecular survival strategies of Echinococcus multilocularis in the murine host. Parasitology international, 55 Suppl, S45-S49. Amsterdam: Elsevier 10.1016/j.parint.2005.11.006

Hemphill, Andrew; Mueller, Joachim; Esposito, Marco (2006). Nitazoxanide, a broad-spectrum thiazolide anti-infective agent for the treatment of gastrointestinal infections. Expert opinion on pharmacotherapy, 7(7), pp. 953-64. London: Informa Healthcare 10.1517/14656566.7.7.953

Hehl, A B; Hemphill, A (2006). The use of light- and electron microscopy for studies on the cell- and molecular biology of parasites and parasitic diseases. Schweizer Archiv für Tierheilkunde, 148(9), pp. 473-81. Bern: Huber 10.1024/0036-7281.148.9.473

Hemphill, A; Vonlaufen, N; Naguleswaran, A (2006). Cellular and immunological basis of the host-parasite relationship during infection with Neospora caninum. Parasitology, 133(Pt 3), pp. 261-78. London: Cambridge University Press 10.1017/S0031182006000485

Hemphill, A; Gottstein, B (2006). Neospora caninum and neosporosis - recent achievements in host and parasite cell biology and treatment. Acta parasitologica, 51(1), pp. 15-25. Warszawa: Versita 10.2478/s11686-006-0002-z

Scheidegger, Alexandra; Vonlaufen, Nathalie Françoise F.; Naguleswaran, Arunasalam; Gianinazzi, Christian; Müller, Norbert; Leib, Stephen; Hemphill, Andrew (2005). Differential effects of interferon-gamma and tumor necrosis factor-alpha on Toxoplasma gondii proliferation in organotypic rat brain slice cultures. Journal of parasitology, 91(2), pp. 307-315. American Society of Parasitologists 10.1645/GE-379R

von Allmen, N; Bienz, M; Hemphill, Andrew; Müller, Norbert (2005). Quantitative assessment of sense and antisense transcripts from genes involved in antigenic variation (vsp genes) and encystation (cwp 1 gene) of Giardia lamblia clone GS/M-83-H7. Parasitology, 130(Pt 4), pp. 389-396. Cambridge University Press

von Allmen, N; Bienz, M; Hemphill, Andrew; Müller, Norbert (2004). Experimental infections of neonatal mice with cysts of Giardia lamblia clone GS/M-83-H7 are associated with an antigenic reset of the parasite. Infection and immunity, 72(8), pp. 4763-4771. American Society for Microbiology 10.1128/IAI.72.8.4763-4771.2004

Stettler, Marianne; Rossignol, Jean François; Fink, Renate; Walker, Mirjam; Gottstein, Bruno; Merli, Michael; Theurillat, Regula; Thormann, Wolfgang; Dricot, Eric; Segers, Rudi; Hemphill, Andrew (2004). Secondary and primary murine alveolar echinococcosis: combined albendazole/nitazoxanide chemotherapy exhibits profound anti-parasitic activity. International journal for parasitology, 34(5), pp. 615-624. Elsevier 10.1016/j.ijpara.2004.01.006

Walker, Mirjam; Baz, Adriana; Dematteis, Sylvia; Stettler, Marianne; Gottstein, Bruno; Schaller, Johann; Hemphill, Andrew (2004). Isolation and characterization of a secretory component of Echinococcus multilocularis metacestodes potentially involved in modulating the host-parasite interface. Infection and immunity, 72(1), pp. 527-536. American Society for Microbiology

Walker, Mirjam; Rossignol, Jean François; Torgerson, Paul; Hemphill, Andrew (2004). In vitro effects of nitazoxanide on Echinococcus granulosus protoscoleces and metacestodes. Journal of antimicrobial chemotherapy, 54(3), pp. 609-616. Oxford University Press 10.1093/jac/dkh386

Cannas, A; Naguleswaran, A; Müller, Norbert; Eperon, S; Gottstein, Bruno; Hemphill, Andrew (2003). Vaccination of mice against experimental Neospora caninum infection using NcSAG1- and NcSRS2-based recombinant antigens and DNA vaccines. Parasitology, 126(04), pp. 303-312. Cambridge University Press 10.1017/S0031182002002895

Stettler, Marianne; Fink, Renate; Walker, Mirjam; Gottstein, Bruno; Geary, Timothy G; Rossignol, Jean François; Hemphill, Andrew (2003). In vitro parasiticidal effect of Nitazoxanide against Echinococcus multilocularis metacestodes. Antimicrobial agents and chemotherapy, 47(2), pp. 467-474. American Society for Microbiology

Hemphill, Andrew; Stettler, Marianne; Walker, Mirjam; Siles-Lucas, Mar; Fink, Renate; Gottstein, Bruno (2003). In vitro culture of Echinococcus multilocularis and Echinococcus vogeli metacestodes: studies on the host-parasite interface. Acta tropica, 85(2), pp. 145-155. Elsevier

Cannas, Angela; Naguleswaran, Arunasalam; Müller, Norbert; Gottstein, Bruno; Hemphill, Andrew (2003). Reduced cerebral infection of Neospora caninum-infected mice after vaccination with recombinant microneme protein NcMIC3 and ribi adjuvant. Journal of parasitology, 89(1), pp. 44-50. American Society of Parasitologists 10.1645/0022-3395(2003)089[0044:RCIONC]2.0.CO;2

Hemphill, Andrew; Stettler, Marianne; Walker, Mirjam; Siles-Lucas, Mar; Fink, Renate; Gottstein, Bruno (2002). Culture of Echinococcus multilocularis metacestodes: an alternative to animal use. Trends in parasitology, 18(10), pp. 445-451. Elsevier Current Trends

Gottstein, Bruno; Dai, Wen Juan; Walker, Mirjam; Stettler, Marianne; Müller, Norbert; Hemphill, Andrew (2002). An intact laminated layer is important for the establishment of secondary Echinococcus multilocularis infection. Parasitology research, 88(9), pp. 822-828. Springer-Verlag 10.1007/s00436-002-0659-7

Dubey, J P; Barr, B C; Barta, J R; Bjerkås, I; Björkman, C; Blagburn, B L; Bowman, D D; Buxton, D; Ellis, J T; Gottstein, Bruno; Hemphill, Andrew; Hill, D E; Howe, D K; Jenkins, M C; Kobayashi, Y; Koudela, B; Marsh, A E; Mattsson, J G; McAllister, M M; Modrý, D; ... (2002). Redescription of Neospora caninum and its differentiation from related coccidia. International journal for parasitology, 32(8), pp. 929-946. Elsevier

Dai, W J; Hemphill, Andrew; Waldvogel, A; Ingold, K; Deplazes, P; Mossmann, H; Gottstein, Bruno (2001). Major carbohydrate antigen of Echinococcus multilocularis induces an immunoglobulin G response independent of alphabeta+ CD4+ T cells. Infection and immunity, 69(10), pp. 6074-6083. American Society for Microbiology 10.1128/IAI.69.10.6074-6083.2001

Müller, Norbert; Sager, Heinz; Hemphill, Andrew; Mehlhorn, H; Heydorn, A O; Gottstein, Bruno (2001). Comparative molecular investigation of Nc5-PCR amplicons from Neospora caninum NC-1 and Hammondia heydorni-Berlin-1996. Parasitology research, 87(10), pp. 883-885. Springer-Verlag 10.1007/s004360100463

Stettler, M; Siles-Lucas, M; Sarciron, E; Lawton, P; Gottstein, Bruno; Hemphill, Andrew (2001). Echinococcus multilocularis alkaline phosphatase as a marker for metacestode damage induced by in vitro drug treatment with albendazole sulfoxide and albendazole sulfone. Antimicrobial agents and chemotherapy, 45(8), pp. 2256-2262. American Society for Microbiology 10.1128/AAC.45.8.2256-2262.2001

Ingold, K; Dai, W; Rausch, R L; Gottstein, Bruno; Hemphill, Andrew (2001). Characterization of the laminated layer of in vitro cultivated Echinococcus vogeli metacestodes. Journal of parasitology, 87(1), pp. 55-64. American Society of Parasitologists 10.1645/0022-3395(2001)087[0055:COTLLO]2.0.CO;2

Felleisen, R S; Hemphill, Andrew; Gottstein, Bruno (2001). A novel EF-hand calcium-binding protein in the flagellum of the protozoan Tritrichomonas suis. Parasitology, 122(02), pp. 125-132. Cambridge University Press 10.1017/S0031182001007168

Hemphill, Andrew; Gottstein, Bruno (2000). A European perspective on Neospora caninum. International journal for parasitology, 30(8), pp. 877-924. Elsevier

Hemphill, Andrew; Müller, N; Sager, H; Gottstein, Bruno (2000). [Neospora caninum and neosporosis--basic science at the Institute of Parasitology and possible implications]. Schweizer Archiv für Tierheilkunde, 142(5), pp. 257-261. Huber

Sonda, S; Fuchs, N; Gottstein, Bruno; Hemphill, Andrew (2000). Molecular characterization of a novel microneme antigen in Neospora caninum. Molecular and biochemical parasitology, 108(1), pp. 39-51. Elsevier

Ingold, K; Gottstein, Bruno; Hemphill, Andrew (2000). High molecular mass glycans are major structural elements associated with the laminated layer of in vitro cultivated Echinococcus multilocularis metacestodes. International journal for parasitology, 30(2), pp. 207-214. Elsevier

Ingold, K; Bigler, P; Thormann, W; Cavaliero, T; Gottstein, Bruno; Hemphill, Andrew (1999). Efficacies of albendazole sulfoxide and albendazole sulfone against In vitro-cultivated Echinococcus multilocularis metacestodes. Antimicrobial agents and chemotherapy, 43(5), pp. 1052-1061. American Society for Microbiology

Eperon, S; Brönnimann, K; Hemphill, Andrew; Gottstein, Bruno (1999). Susceptibility of B-cell deficient C57BL/6 (microMT) mice to Neospora caninum infection. Parasite immunology, 21(5), pp. 225-236. Blackwell Scientific Publications

Hemphill, Andrew; Gajendran, N; Sonda, S; Fuchs, N; Gottstein, Bruno; Hentrich, B; Jenkins, M (1998). Identification and characterisation of a dense granule-associated protein in Neospora caninum tachyzoites. International journal for parasitology, 28(3), pp. 429-438. Elsevier

Gottstein, Bruno; Hemphill, Andrew (1997). Immunopathology of echinococcosis. Chemical immunology, 66, pp. 177-208. Karger

Hemphill, Andrew; Stäger, S; Gottstein, Bruno; Müller, Norbert (1996). Electron microscopical investigation of surface alterations on Giardia lamblia trophozoites after exposure to a cytotoxic monoclonal antibody. Parasitology research, 82(3), pp. 206-210. Springer-Verlag 10.1007/s004360050096

Hemphill, Andrew; Gottstein, Bruno (1996). Identification of a major surface protein on Neospora caninum tachyzoites. Parasitology research, 82(6), pp. 497-504. Springer-Verlag 10.1007/s004360050152

Imboden, M.; Müller, N.; Hemphill, A.; Mattioli, R.; Seebeck, T. (1995). Repetitive proteins from the flagellar cytoskeleton of African trypanosomes are diagnostically useful antigens. Parasitology, 110(3), pp. 249-258. Cambridge University Press 10.1017/S0031182000080835

Hemphill, Andrew; Gottstein, Bruno (1995). Immunology and morphology studies on the proliferation of in vitro cultivated Echinococcus multilocularis metacestodes. Parasitology research, 81(7), pp. 605-614. Springer-Verlag 10.1007/BF00932028

Hemphill, A.; Frame, I.; Ross, C. A. (1994). The interaction of Trypanosoma congolense with endothelial cells. Parasitology, 109(5), pp. 631-641. Cambridge University Press 10.1017/S0031182000076514