Leib, Stephen

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2016

Koller, Roger; Barbani, Maria Teresa; Lüthi, Alexander; Zürcher, Samuel; Steinlin, Jacqueline; Leib, Stephen; Gorgievski, Meri (September 2016). Comparison of respiratory and Meningitis/Encephalitis viruses detected by FilmArray® multiplex PCR versus real-time PCR. Journal of clinical virology, 82, S39. Elsevier 10.1016/j.jcv.2016.08.076

Perny, Michael; Roccio, Marta; Grandgirard, Denis; Solyga, Magdalena; Senn, Pascal; Leib, Stephen (2016). The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis. Journal of neuroscience, 36(29), pp. 7740-7749. Society for Neuroscience 10.1523/JNEUROSCI.0554-16.2016

Curiao, Tânia; Marchi, Emmanuela; Grandgirard, Denis; León-Sampedro, Ricardo; Viti, Carlo; Leib, Stephen; Baquero, Fernando; Oggioni, Marco R; Martinez, José Luis; Coque, Teresa M (2016). Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure. BMC Genomics, 17(491), p. 491. BioMed Central 10.1186/s12864-016-2778-z

van de Beek, D; Cabellos, C; Dzupova, O; Esposito, S; Klein, M; Kloek, A T; Leib, Stephen; Mourvillier, B; Ostergaard, C; Pagliano, P; Pfister, H W; Read, R C; Sipahi, O Resat; Brouwer, M C (2016). ESCMID guideline: diagnosis and treatment of acute bacterial meningitis. Clinical microbiology and infection, 22(Suppl 3), S37-S62. Blackwell Publishing 10.1016/j.cmi.2016.01.007

Cag, Y; Erdem, H; Leib, Stephen; Defres, S; Kaya, S; Larsen, L; Poljak, M; Ozturk-Engin, D; Barsic, B; Argemi, X; Sørensen, S M; Bohr, A L; Tattevin, P; Gunst, J D; Baštáková, L; Jereb, M; Johansen, I S; Karabay, O; Pekok, A U; Sipahi, O R; ... (2016). Managing atypical and typical herpetic central nervous system infections: results of a multinational study. Clinical microbiology and infection, 22(6), 568.e9-568.e17. Blackwell Publishing 10.1016/j.cmi.2016.03.027

Fernández-López, David; Faustino, Joel; Klibanov, Alexander L; Derugin, Nikita; Blanchard, Elodie; Simon, Franziska; Leib, Stephen; Vexler, Zinaida S (2016). Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke. Journal of neuroscience, 36(10), pp. 2881-2893. Society for Neuroscience 10.1523/JNEUROSCI.0140-15.2016

Bürki, Sarah Elisabeth; Grandgirard, Denis; Datta, Alexandre N; Hackenberg, Annette; Martin, Florence; Schmitt-Mechelke, Thomas; Leib, Stephen L; Steinlin, Maja (2016). Inflammatory markers in pediatric stroke: An attempt to better understanding the pathophysiology. European journal of paediatric neurology, 20(2), pp. 252-260. Elsevier 10.1016/j.ejpn.2015.12.006

Bally, Lia; Grandgirard, Denis; Leib, Stephen (2016). Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis. Antimicrobial agents and chemotherapy, 60(3), pp. 1841-1846. American Society for Microbiology 10.1128/AAC.02429-15

Hathaway, Lucy Jane; Grandgirard, Denis; Valente, Luca Gabriele; Täuber, Martin G.; Leib, Stephen (2016). Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis. Open Biology, 6(3) The Royal Society Publishing 10.1098/rsob.150269

Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8

Baumgartner, Denja; Aebi, Susanne; Grandgirard, Denis; Leib, Stephen; Draeger, Annette; Babiychuk, Eduard; Hathaway, Lucy Jane (2016). Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes. BMC microbiology, 16(1), p. 154. BioMed Central 10.1186/s12866-016-0777-5

2015

Medaglini, Donata; Harandi, Ali M; Ottenhoff, Tom H M; Siegrist, Claire-Anne; VSV-Ebovac Consortium, ; Leib, Stephen (2015). Ebola vaccine R&D: Filling the knowledge gaps. Science translational medicine, 7(317), 317ps24. American Association for the Advancement of Science 10.1126/scitranslmed.aad3106

Pires, João; Siriwardena, Thissa N.; Stach, Michaela; Tinguely, Regula; Kasraian Fard, Sara; Luzzaro, Francesco; Leib, Stephen; Darbre, Tamis; Reymond, Jean-Louis; Endimiani, Andrea (2015). In Vitro Activity of the Novel Antimicrobial Peptide Dendrimer G3KL against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 59(12), pp. 7915-7918. American Society for Microbiology 10.1128/AAC.01853-15

Frick, Tamara; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Hänggi, Matthias (2015). An improved simple rat model for global cerebral ischaemia by induced cardiac arrest. Neurological research, 38(4), pp. 373-380. Maney 10.1179/1743132815Y.0000000090

Liechti, Fabian D; Grandgirard, Denis; Leib, Stephen (2015). Bacterial meningitis: insights into pathogenesis and evaluation of new treatment options: a perspective from experimental studies. Future microbiology, 10(7), pp. 1195-1213. Future Medicine 10.2217/fmb.15.43

Liechti, F D; Grandgirard, Denis; Leib, Stephen (2015). The antidepressant fluoxetine protects the hippocampus from brain damage in experimental pneumococcal meningitis. Neuroscience, 297, pp. 89-94. Elsevier 10.1016/j.neuroscience.2015.03.056

Osthoff, Michael; Egli, Adrian; Schürch, Nadia; Leib, Stephen; Mihatsch, Felix; Frei, Reno (2015). Ein nicht alltägliches türkisches Souvenir. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 15(25), pp. 611-613. EMH Editores Medicorum Helveticorum

Grandgirard, Denis; Furi, Leonardo; Ciusa, Maria Laura; Baldassarri, Lucilla; Knight, Daniel R; Morrissey, Ian; Largiadèr, Carlo Rodolfo; Leib, Stephen; Oggioni, Marco R (2015). Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression. BMC Genomics, 16(345), p. 345. BioMed Central 10.1186/s12864-015-1544-y

Wang, Junhua; Vuitton, Dominique A; Müller, Norbert; Hemphill, Andrew; Spiliotis, Markus; Blagosklonov, Oleg; Grandgirard, Denis; Leib, Stephen; Shalev, Itay; Levy, Gary; Lu, Xiaomei; Lin, Renyong; Wen, Hao; Gottstein, Bruno (2015). Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice. PLoS neglected tropical diseases, 9(5), e0003755. Public Library of Science 10.1371/journal.pntd.0003755

Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC Anaesthesiology, 15(2), p. 2. Biomed Central 10.1186/1471-2253-15-2

Liechti, Fabian D; Bächtold, Fabian; Grandgirard, Denis; Leppert, David; Leib, Stephen (2015). The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis. Journal of neuroinflammation, 12(43), p. 43. BioMed Central 10.1186/s12974-015-0257-0

Fontes, Fabrícia Lima; de Araújo, Luíza Ferreira; Coutinho, Leonam Gomes; Leib, Stephen; Agnez-Lima, Lucymara Fassarella (2015). Genetic polymorphisms associated with the inflammatory response in bacterial meningitis. BMC medical genetics, 16(70), p. 70. BioMed Central 10.1186/s12881-015-0218-6

Oggioni, Marco R; Coelho, Joana Rosado; Furi, Leonardo; Knight, Daniel R; Viti, Carlo; Orefici, Graziella; Martinez, Jose-Luis; Freitas, Ana Teresa; Coque, Teresa M; Morrissey, Ian; BIOHYPO consortium, ; Leib, Stephen (2015). Significant Differences Characterise the Correlation Coefficients between Biocide and Antibiotic Susceptibility Profiles in Staphylococcus aureus. Current pharmaceutical design, 21(16), pp. 2054-2057. Bentham Science Publishers 10.2174/1381612821666150310103238

2014

Ricci, Susanna; Grandgirard, Denis; Wenzel, Michael; Braccini, Tiziana; Salvatore, Paola; Oggioni, Marco R; Leib, Stephen; Koedel, Uwe (2014). Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis. BMC infectious diseases, 14(726), p. 726. BioMed Central 10.1186/s12879-014-0726-6

Maffioli, Carola; Grandgirard, Denis; Engler, Olivier; Leib, Stephen (2014). A tick-borne encephalitis model in infant rats infected with langat virus. Journal of neuropathology and experimental neurology, 73(12), pp. 1107-1115. Lippincott Williams & Wilkins 10.1097/NEN.0000000000000131

Coutinho, Leonam G; Christen, Stephan; Bellac, Caroline L; Fontes, Fabrícia; de Souza, Fladjule; Grandgirard, Denis; Leib, Stephen; Agnez-Lima, Lucymara F (2014). The kynurenine pathway is involved in bacterial meningitis. Journal of neuroinflammation, 11(169), p. 169. BioMed Central 10.1186/s12974-014-0169-4

Agyeman, Philipp; Grandgirard, Denis; Leib, Stephen (2014). Pathogenesis and Pathophysiology of Bacterial Infections. In: Scheld, Michael; Whitley, Richard J.; Marra, Christina M. (eds.) Infections of the Central Nervous System (pp. 341-364). Philadelphia, PA, USA: Lippincott Williams & Wilkins

Liechti, Fabian D; Grandgirard, Denis; Leppert, David; Leib, Stephen (2014). Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis. Infection and immunity, 82(4), pp. 1710-1718. American Society for Microbiology 10.1128/IAI.00073-14

Hirt-Minkowski, Patricia; Marti, Hans-Peter; Hönger, Gideon; Grandgirard, Denis; Leib, Stephen; Amico, Patrizia; Schaub, Stefan (2014). Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation. Transplant immunology, 30(1), pp. 1-6. Elsevier 10.1016/j.trim.2013.11.004

Holler, Jon G.; Brandt, Christian T.; Leib, Stephen L.; Rowland, Ian J.; Ostergaard, Christian (2014). Increase in hippocampal water diffusion and volume during experimental pneumococcal meningitis is aggravated by bacteremia. BMC infectious diseases, 14(1), p. 240. BioMed Central 10.1186/1471-2334-14-240

Liechti, Fabian D; Stüdle, Nicolas; Theurillat, Regula; Grandgirard, Denis; Thormann, Wolfgang; Leib, Stephen (2014). The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis. PLoS ONE, 9(11), e113607. Public Library of Science 10.1371/journal.pone.0113607

Baranger, Kévin; Rivera, Santiago; Liechti, Fabian D; Grandgirard, Denis; Bigas, Judit; Seco, Jesús; Tarrago, Teresa; Leib, Stephen; Khrestchatisky, Michel (2014). Endogenous and synthetic MMP inhibitors in CNS physiopathology. In: Dityatev, Alexander; Wehrle-Haller, Bernhard; Pitkänen, Asla (eds.) Brain Extracellular Matrix in Health and Disease. Progress in Brain Research: Vol. 214 (pp. 313-351). Elsevier 10.1016/B978-0-444-63486-3.00014-1

2013

Peltola, Heikki; Leib, Stephen L. (2013). Performance of adjunctive therapy in bacterial meningitis depends on circumstances. Pediatric infectious disease journal, 32(12), pp. 1381-1382. Lippincott Williams & Wilkins 10.1097/INF.0000000000000066

Coutinho, Leonam G; Grandgirard, Denis; Leib, Stephen L.; Agnez-Lima, Lucymara F (2013). Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis. BMC infectious diseases, 13(1), p. 326. BioMed Central 10.1186/1471-2334-13-326

Jansen, Sandra; Podschun, Rainer; Leib, Stephen L.; Grötzinger, Joachim; Oestern, Stefanie; Michalek, Matthias; Pufe, Thomas; Brandenburg, Lars-Ove (2013). Expression and function of psoriasin (S100A7) and koebnerisin (S100A15) in the brain. Infection and immunity, 81(5), pp. 1788-1797. American Society for Microbiology 10.1128/IAI.01265-12

Comim, Clarissa M; Barichello, Tatiana; Grandgirard, Denis; Dal-Pizzol, Felipe; Quevedo, João; Leib, Stephen L.; Leib, Stephen (2013). Caspase-3 mediates in part hippocampal apoptosis in sepsis. Molecular neurobiology, 47(1), pp. 394-8. Clifton, N.J.: Humana Press 10.1007/s12035-012-8354-x

Monney, Thierry; Grandgirard, Denis; Leib, Stephen; Hemphill, Andrew (2013). Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model. Pathogens, 2(2), pp. 193-208. MDPI AG 10.3390/pathogens2020193

Zysset-Burri, Denise C.; Bellac, Caroline L; Leib, Stephen L.; Wittwer, Matthias (2013). Vitamin B6 reduces hippocampal apoptosis in experimental pneumococcal meningitis. BMC infectious diseases, 13, p. 393. BioMed Central 10.1186/1471-2334-13-393

Grandgirard, Denis; Gäumann, Rahel; Coulibaly, Boubacar; Dangy, Jean-Pierre; Sie, Ali; Junghanss, Thomas; Schudel, Hans; Pluschke, Gerd; Leib, Stephen L. (2013). The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis. Mediators of inflammation, 2013, p. 312476. Hindawi Publishing Corp. 10.1155/2013/312476

2012

Jegerlehner, Sabrina; Vogel, Daniel; Tappeiner, Christoph; Leib, Stephen (2012). What vision loss might bring to light. Praxis - schweizerische Rundschau für Medizin, 101(6), pp. 419-423. Bern: Huber 10.1024/1661-8157/a000869

Mitchell, Andrew J.; Yau, Belinda; McQuillan, James A; Ball, Helen J.; Too, Lay Khoon; Abtin, Arby; Hertzog, Paul; Leib, Stephen L.; Jones, Cheryl A.; Gerega, Sebastien K.; Weninger, Wolfgang; Hunt, Nicholas H. (2012). Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis. Journal of immunology, 189(10), pp. 4970-80. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1201687

Maffioli, Carola; Grandgirard, Denis; Engler, Olivier; Leib, Stephen L.; Leib, Stephen (2012). SiRNA inhibits replication of Langat virus, a member of the tick-borne encephalitis virus complex in organotypic rat brain slices. PLoS ONE, 7(9), e44703. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0044703

Monney, Thierry; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew; Leib, Stephen (2012). Vaccination with the recombinant chimeric antigen recNcMIC3-1-R induces a non-protective Th2-type immune response in the pregnant mouse model for N. caninum infection. Vaccine, 30(46), pp. 6588-94. Amsterdam: Elsevier 10.1016/j.vaccine.2012.08.024

Guldimann, Claudia; Lejeune, Beatrice; Hofer, Sandra; Leib, Stephen L.; Frey, Joachim; Zurbriggen, Andreas; Seuberlich, Torsten; Oevermann, Anna (2012). Ruminant organotypic brain-slice cultures as a model for the investigation of CNS listeriosis. International journal of experimental pathology, 93(4), pp. 259-268. Oxford: Blackwell Science 10.1111/j.1365-2613.2012.00821.x

Grandgirard, Denis; Burri, Melchior; Agyeman, Philipp; Leib, Stephen (2012). Adjunctive daptomycin attenuates brain damage and hearing loss more efficiently than rifampin in infant rat pneumococcal meningitis. Antimicrobial agents and chemotherapy, 56(8), pp. 4289-95. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00674-12

Hofer, Sandra; Magloire, Vincent; Streit, Jürg; Leib, Stephen L.; Leib, Stephen (2012). Grafted neuronal precursor cells differentiate and integrate in injured hippocampus in experimental pneumococcal meningitis. Stem cells, 30(6), pp. 1206-15. Durham: AlphaMed Press

2011

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Woehrl, Bianca; Klein, Matthias; Grandgirard, Denis; Koedel, Uwe; Leib, Stephen (2011). Bacterial meningitis: current therapy and possible future treatment options. Expert review of anti-infective therapy, 9(11), pp. 1053-1065. London: Expert Reviews 10.1586/ERI.11.129

Hofer, Sandra; Grandgirard, Denis; Burri, Denise; Fröhlich, Tanja K.; Leib, Stephen L. (2011). Bacterial meningitis impairs hippocampal neurogenesis. Journal of neuropathology and experimental neurology, 70(10), pp. 890-899. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e3182303f31

Monney, Thierry; Rütti, David; Schorer, Michelle; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew (2011). RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection. Vaccine, 29(40), pp. 6967-6975. Amsterdam: Elsevier 10.1016/j.vaccine.2011.07.038

da Silva, Thayse Azevedo; Fontes, Fabrícia Lima; Coutinho, Leonam Gomes; de Souza, Fladjule Rejane Soares; de Melo, Julliane Tamara Araújo; de Souto, Janeusa Trindade; Leib, Stephen L.; Agnez-Lima, Lucymara Fassarella (2011). SNPs in DNA repair genes associated to meningitis and host immune response. Mutation research - fundamental and molecular mechanisms of mutagenesis, 713(1-2), pp. 39-47. Amsterdam: Elsevier 10.1016/j.mrfmmm.2011.05.012

de Souza, Fladjule Rejane Soares; Fontes, Fabrícia Lima; da Silva, Thayse Azevedo; Coutinho, Leonam Gomes; Leib, Stephen L.; Agnez-Lima, Lucymara Fassarella (2011). Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis. BMC medical genetics, 12(51), p. 51. London: BioMed Central 10.1186/1471-2350-12-51

Blaser, Cornelia; Wittwer, Matthias; Grandgirard, Denis; Leib, Stephen L. (2011). Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis. PLoS ONE, 6(3), e17840. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0017840

Braun, Benedikt J.; Slowik, Alexander; Leib, Stephen L.; Lucius, Ralph; Varoga, Deike; Wruck, Christoph J.; Jansen, Sandra; Podschun, Rainer; Pufe, Thomas; Brandenburg, Lars-Ove (2011). The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis. Journal of neuroinflammation, 8(1), p. 11. London: BioMed Central 10.1186/1742-2094-8-11

Margos, M.C.; Grandgirard, Denis; Leib, Stephen; Gottstein, Bruno (2011). In vitro induction of lymph node cell proliferation by mouse bone marrow dendritic cells following stimulation with different Echinococcus multilocularis antigens. Journal of helminthology, 85(2), pp. 128-137. Cambridge: Cambridge University Press 10.1017/S0022149X10000878

2010

Gottstein, Bruno; Wittwer, Matthias; Schild, Marc; Merli, Michael; Leib, Stephen L.; Müller, Norbert; Müller, Joachim; Jaggi, Rolf (2010). Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggs. PLoS ONE, 5(4), e9779. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0009779

Bellac, Caroline L.; Coimbra, Roney S.; Christen, Stephan; Leib, Stephen L. (2010). Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology, 69(11), pp. 1096-1104. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e3181f7e7e9

Grandgirard, Denis; Leib, Stephen L. (2010). Meningitis in neonates: bench to bedside. Clinics in perinatology, 37(3), pp. 655-676. New York, N.Y.: Elsevier 10.1016/j.clp.2010.05.004

Wittwer, Matthias; Grandgirard, Denis; Rohrbach, Janine; Leib, Stephen L. (2010). Tracking the transcriptional host response from the acute to the regenerative phase of experimental pneumococcal meningitis. BMC infectious diseases, 10(176), p. 176. London: BioMed Central 10.1186/1471-2334-10-176

Blaser, Cornelia; Klein, Matthias; Grandgirard, Denis; Wittwer, Matthias; Peltola, Heikki; Weigand, Michael; Koedel, Uwe; Leib, Stephen L. (2010). Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis. BMC infectious diseases, 10(84), p. 84. London: BioMed Central 10.1186/1471-2334-10-84

Sellner, Johann; Täuber, Martin G.; Leib, Stephen L. (2010). Pathogenesis and pathophysiology of bacterial CNS infections. Handbook of clinical neurology, 96, pp. 1-16. Amsterdam: Elsevier 10.1016/S0072-9752(09)96001-8

Grandgirard, Denis; Oberson, Kevin; Bühlmann, Angela; Gäumann, Rahel; Leib, Stephen L. (2010). Attenuation of cerebrospinal fluid inflammation by the nonbacteriolytic antibiotic daptomycin versus that by ceftriaxone in experimental pneumococcal meningitis. Antimicrobial agents and chemotherapy, 54(3), pp. 1323-1326. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00812-09

Østergaard, Christian; Leib, Stephen L.; Rowland, Ian; Brandt, Christian T. (2010). Bacteremia causes hippocampal apoptosis in experimental pneumococcal meningitis. BMC infectious diseases, 10(1), p. 1. London: BioMed Central 10.1186/1471-2334-10-1

2009

Klein, M; Pfister, H W; Leib, Stephen L.; Koedel, U (2009). Therapy of community-acquired acute bacterial meningitis: the clock is running. Expert opinion on pharmacotherapy, 10(16), pp. 2609-2623. Informa Healthcare 10.1517/14656560903277210

Sellner, Johann; Buonomano, Roberto; Nedeltchev, Krassen; Findling, Oliver; Schroth, Gerhard; Surbek, Daniel; Leib, Stephen L. (2009). A case of maternal herpes simplex virus encephalitis during late pregnancy. Nature clinical practice - neurology, 5(1), pp. 51-56. New York, N.Y.: Nature Publishing Group 10.1038/ncpneuro0972

Stickel, Felix; Droz, Sara; Patsenker, Eleonora; Bögli-Stuber, Katja; Aebi, Beat; Leib, Stephen L. (2009). Severe hepatotoxicity following ingestion of Herbalife nutritional supplements contaminated with Bacillus subtilis. Journal of hepatology, 50(1), pp. 111-117. Amsterdam: Elsevier 10.1016/j.jhep.2008.08.017

Brandenburg, Lars-Ove; Varoga, Deike; Nicolaeva, Nicoletta; Leib, Stephen L.; Podschun, Rainer; Wruck, Christoph J.; Wilms, Henrik; Lucius, Ralph; Pufe, Thomas (2009). Expression and regulation of antimicrobial peptide rCRAMP after bacterial infection in primary rat meningeal cells. Journal of neuroimmunology, 217(1-2), pp. 55-64. Amsterdam: Elsevier 10.1016/j.jneuroim.2009.10.004

Debache, Karim; Alaeddine, Ferial; Guionaud, Christophe; Monney, Thierry; Müller, Joachim; Strohbusch, Maria; Leib, Stephen L.; Grandgirard, Denis; Hemphill, Andrew (2009). Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites. International journal for parasitology, 39(12), pp. 1373-1384. Kidlington, UK: Elsevier 10.1016/j.ijpara.2009.04.006

Sellner, Johann; Grandgirard, Denis; Gianinazzi, Christian; Landmann, Regine M.; Leib, Stephen L. (2009). Effects of Toll-like receptor 2 agonist Pam(3)CysSK(4) on inflammation and brain damage in experimental pneumococcal meningitis. Journal of neuroimmunology, 206(1-2), pp. 28-31. Amsterdam: Elsevier 10.1016/j.jneuroim.2008.10.004

Strohbusch, M.; Muller, N.; Hemphill, A.; Margos, M.; Grandgirard, D.; Leib, Stephen; Greif, G.; Gottstein, B. (2009). Neospora caninum and bone marrow-derived dendritic cells: parasite survival, proliferation, and induction of cytokine expression. Parasite immunology, 31(7), pp. 366-372. Oxford: Blackwell Scientific Publications 10.1111/j.1365-3024.2009.01112.x

Horvath, Christina E.; Brinkmann, Christian K.; Ozdoba, Christoph; Leib, Stephen; Wolf, Sebastian; Wolf-Schnurrbusch, Ute E.K. (2009). Chorioretinal nocardiosis. Retinal Cases & Brief Reports, 3(3), pp. 263-265. Lippincott Williams & Wilkins 10.1097/ICB.0b013e31817376eb

2008

Gehre, F.; Leib, Stephen L.; Grandgirard, Denis; Kummer, Jürg; Bühlmann, Angela; Simon, Franziska; Gäumann, R.; Kharat, A. S.; Täuber, Martin G.; Tomasz, A. (2008). Essential role of choline for pneumococcal virulence in an experimental model of meningitis. Internal medicine journal, 264(2), pp. 143-154. Sydney: Blackwell 10.1111/j.1365-2796.2008.01930.x

Sury, Matthias D.; Agarinis, Claudia; Widmer, Hans-Rudolf; Leib, Stephen L.; Christen, Stephan (2008). JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 32(1), pp. 142-150. Amsterdam: Elsevier 10.1016/J.nbd.2008.07.006

Sellner, Johann; Greeve, Isabell; Findling, Oliver; Kamm, Christian P.; Minten, Carsten; Engelhardt, Britta; Grandgirard, Denis; Leib, Stephen L.; Mattle, Heinrich P (2008). Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis. Neurochemistry international, 53(1-2), pp. 17-21. Amsterdam: Elsevier 10.1016/j.neuint.2008.04.004

Brandenburg, Lars-Ove; Varoga, Deike; Nicolaeva, Nicoletta; Leib, Stephen L.; Wilms, Henrik; Podschun, Rainer; Wruck, Christoph J; Schröder, Jens-Michael; Pufe, Thomas; Lucius, Ralph (2008). Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis. Journal of neuropathology and experimental neurology, 67(11), pp. 1041-1054. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e31818b4801

Grandgirard, Denis; Loeffler, Jutta M.; Fischetti, Vincent A.; Leib, Stephen L. (2008). Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis. Journal of infectious diseases, 197(11), pp. 1519-1522. Cary, N.C.: Oxford University Press 10.1086/587942

Sellner, Johann; Ringer, Ralph; Baumann, Pierre; Perey, Michèl Jonzier; Schmitt, Bernhard; Leib, Stephen L. (2008). Effect of the NMDA-receptor antagonist dextromethorphan in infant rat pneumococcal meningitis. Current drug metabolism, 9(1), pp. 83-88. Hilversum: Bentham Science Publishers

Sellner, Johann; Greeve, Isabell; Leib, Stephen L.; Mattle, Heinrich P. (2008). Atorvastatin does not alter interferon Beta-induced changes of serum matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 in patients with multiple sclerosis. Archives of neurology, 65(5), pp. 672-674. Chicago, Ill.: American Medical Association 10.1001/archneur.65.5.672

Sellner, Johann; Greeve, I; Findling, O; Grandgirard, Denis; Leib, Stephen L.; Mattle, H P (2008). Atorvastatin does not alter serum levels of sCD95 and sCD95L in multiple sclerosis. Clinical and experimental immunology, 152(2), pp. 280-284. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2008.03630.x

2007

Ren, Hao; Leib, Stephen L.; Ferriero, Donna M; Täuber, Martin G.; Christen, Stephan (2007). Induction of haem oxygenase-1 causes cortical non-haem iron increase in experimental pneumococcal meningitis: evidence that concomitant ferritin up-regulation prevents iron-induced oxidative damage. Journal of neurochemistry, 100(2), pp. 532-544. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2006.04230.x

Grandgirard, Denis; Steiner, Oliver; Täuber, Martin G.; Leib, Stephen L. (2007). An infant mouse model of brain damage in pneumococcal meningitis. Acta neuropathologica, 114(6), pp. 609-617. Berlin: Springer 10.1007/s00401-007-0304-8

Trampuz, Andrej; Steinhuber, Andrea; Wittwer, Matthias; Leib, Stephen L. (2007). Rapid diagnosis of experimental meningitis by bacterial heat production in cerebrospinal fluid. BMC infectious diseases, 7, p. 116. London: BioMed Central 10.1186/1471-2334-7-116

Bellac, Caroline L; Coimbra, Roney S; Simon, Franziska; Imboden, Johann; Leib, Stephen L. (2007). Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis. Neurobiology of disease, 28(2), pp. 175-183. Amsterdam: Elsevier 10.1016/j.nbd.2007.07.005

Coimbra, Roney S; Loquet, Gérard; Leib, Stephen L. (2007). Limited efficacy of adjuvant therapy with dexamethasone in preventing hearing loss due to experimental pneumococcal meningitis in the infant rat. Pediatric research, 62(3), pp. 291-294. New York, N.Y.: Nature Publishing Group 10.1203/PDR.0b013e318123fb7c

Zimmerli, Stefan; Knecht, Urspeter; Leib, Stephen L. (2007). A model of cerebral aspergillosis in non-immunosuppressed nursing rats. Acta neuropathologica, 114(4), pp. 411-418. Berlin: Springer 10.1007/s00401-007-0255-0

Echchannaoui, Hakim; Leib, Stephen L.; Neumann, Ulf; Landmann, Regine M. A. (2007). Adjuvant TACE inhibitor treatment improves the outcome of TLR2-/- mice with experimental pneumococcal meningitis. BMC infectious diseases, 7(25), p. 25. London: BioMed Central 10.1186/1471-2334-7-25

Grandgirard, Denis; Schürch, Christian; Cottagnoud, Philippe; Leib, Stephen L. (2007). Prevention of brain injury by the nonbacteriolytic antibiotic daptomycin in experimental pneumococcal meningitis. Antimicrobial agents and chemotherapy, 51(6), pp. 2173-2178. Washington, D.C.: American Society for Microbiology 10.1128/AAC.01014-06

Grandgirard, D; Bifrare, Y-D; Pleasure, S J; Kummer, J; Leib, Stephen L.; Tauber, Martin G. (2007). Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats. Developmental neuroscience, 29(1-2), pp. 134-142. Basel: Karger 10.1159/000096218

Sellner, Johann; Leib, Stephen L. (2007). Flu-related neurological complications: incidence and risk factors in children. Nature clinical practice - neurology, 3(11), pp. 606-607. New York, N.Y.: Nature Publishing Group 10.1038/ncpneuro0610

Leib, Stephen L. (2007). An in vitro model of central nervous system infection and regeneration: neuronal stem cells as targets of brain damage and regenerative therapies in bacterial meningitis. ALTEX-Alternatives to Animal Experimentation, 24 Spec No, pp. 90-92. Springer

2006

Rauch, A; Droz, S; Zimmerli, Stefan; Leib, Stephen L. (2006). Dysphagia in elderly women: consider tetanus. Infection, 34(1), pp. 35-38. Heidelberg: Springer-Medizin-Verlag 10.1007/s15010-006-4151-7

Sellner, Johann; Simon, Franziska; Meyding-Lamade, Uta; Leib, Stephen L. (2006). Herpes-simplex virus encephalitis is characterized by an early MMP-9 increase and collagen type IV degradation. Brain research, 1125(1), pp. 155-162. Amsterdam: Elsevier 10.1016/j.brainres.2006.09.093

Sellner, Johann; Leib, Stephen L. (2006). In bacterial meningitis cortical brain damage is associated with changes in parenchymal MMP-9/TIMP-1 ratio and increased collagen type IV degradation. Neurobiology of disease, 21(3), pp. 647-656. Amsterdam: Elsevier 10.1016/j.nbd.2005.09.007

Bellac, Caroline L.; Coimbra, Roney S.; Christen, Stephan; Leib, Stephen L. (2006). Pneumococcal meningitis causes accumulation of neurotoxic kynurenine metabolites in brain regions prone to injury. Neurobiology of disease, 24(2), pp. 395-402. Amsterdam: Elsevier 10.1016/j.nbd.2006.07.014

Boscacci, Rémy; Leib, Stephen L. (2006). [Invasive meningococcal infections: two cases that demonstrate the broad spectrum in clinical manifestation and outcome]. Praxis - schweizerische Rundschau für Medizin, 95(43), pp. 1675-1678. Bern: Huber 10.1024/1661-8157.95.43.1675

Meli, Damian N.; Coimbra, Roney S.; Erhart, Dominik G.; Loquet, Gerard; Bellac, Caroline L.; Täuber, Martin G.; Neumann, Ulf; Leib, Stephen L. (2006). Doxycycline reduces mortality and injury to the brain and cochlea in experimental pneumococcal meningitis. Infection and immunity, 74(7), pp. 3890-3896. New York, N.Y.: American Society for Microbiology 10.1128/IAI.01949-05

Coimbra, Roney S.; Voisin, Veronique; de Saizieu, Antoine B.; Lindberg, Raija L. P.; Wittwer, Matthias; Leppert, David; Leib, Stephen L. (2006). Gene expression in cortex and hippocampus during acute pneumococcal meningitis. BMC biology, 4, p. 15. London: BioMed Central 10.1186/1741-7007-4-15

Grandgirard, Denis; Leib, Stephen L. (2006). Strategies to prevent neuronal damage in paediatric bacterial meningitis. Current opinion in pediatrics, 18(2), pp. 112-118. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/01.mop.0000193292.09894.b7

Lindberg, R L P; Sorsa, T; Tervahartiala, T; Hoffmann, F; Mellanen, L; Kappos, L; Schaad, U B; Leib, Stephen L.; Leppert, D (2006). Gelatinase B [matrix metalloproteinase (MMP)-9] and collagenases (MMP-8/-13) are upregulated in cerebrospinal fluid during aseptic and bacterial meningitis in children. Neuropathology & applied neurobiology, 32(3), pp. 304-317. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2990.2006.00729.x

Zucker, K E; Kamberi, P; Sobel, R A; Cloud, G; Meli, D N; Clemons, K V; Stevens, D A; Williams, P L; Leib, Stephen L. (2006). Temporal expression of inflammatory mediators in brain basilar artery vasculitis and cerebrospinal fluid of rabbits with coccidioidal meningitis. Clinical and experimental immunology, 143(3), pp. 458-466. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2006.03011.x

2005

Gianinazzi, Christian; Schild, Marc; Müller, Nicole; Leib, Stephen; Simon, F; Nunez, Sandra; Joss, Philipp; Gottstein, Bruno (2005). Organotypic slice cultures from rat brain tissue: a new approach for Naegleria fowleri CNS infection in vitro. Parasitology, 131(6), pp. 797-804. Cambridge University Press 10.1017/S0031182005008619

Scheidegger, Alexandra; Vonlaufen, Nathalie Françoise F.; Naguleswaran, Arunasalam; Gianinazzi, Christian; Müller, Norbert; Leib, Stephen; Hemphill, Andrew (2005). Differential effects of interferon-gamma and tumor necrosis factor-alpha on Toxoplasma gondii proliferation in organotypic rat brain slice cultures. The Journal of parasitology, 91(2), pp. 307-315. 10.1645/GE-379R

Bifrare, Yoeng-Delphine; Kummer, Jürg; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2005). Brain-derived neurotrophic factor protects against multiple forms of brain injury in bacterial meningitis. Journal of infectious diseases, 191(1), pp. 40-45. Oxford University Press 10.1086/426399

2004

Meli, D. N.; Loeffler, J. M.; Baumann, P.; Neumann, U.; Buhl, T.; Leppert, D.; Leib, Stephen (2004). In pneumococcal meningitis a novel water-soluble inhibitor of matrix metalloproteinases and TNF-alpha converting enzyme attenuates seizures and injury of the cerebral cortex. Journal of neuroimmunology, 151(1-2), pp. 6-11. Elsevier 10.1016/j.jneuroim.2004.01.026

Gianinazzi, Christian; Grandgirard, Denis; Simon, Franziska; Imboden, Hans; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2004). Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited. Journal of neuropathology and experimental neurology, 63(6), pp. 610-617. Lippincott Williams & Wilkins

2003

Leib, Stephen; Heimgartner, Chris; Bifrare, Yoeng-Delphine; Loeffler, Jutta M; Täuber, Martin G. (2003). Dexamethasone aggravates hippocampal apoptosis and learning deficiency in pneumococcal meningitis in infant rats. Pediatric research, 54(3), pp. 353-357. Nature Publishing Group 10.1203/01.PDR.0000079185.67878.72

Schaper, Manuela; Leib, Stephen; Meli, Damian N; Brandes, Ralf P; Täuber, Martin G.; Christen, Stephan (2003). Differential effect of p47phox and gp91phox deficiency on the course of Pneumococcal Meningitis. Infection and immunity, 71(7), pp. 4087-4092. American Society for Microbiology 10.1128/IAI.71.7.4087-4092.2003

Ghielmetti, Marco; Ren, Hao; Leib, Stephen; Täuber, Martin G.; Christen, Stephan (2003). Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis. Brain research, 976(2), pp. 139-148. Elsevier 10.1016/S0006-8993(03)02557-5

Fux, C; Bodmer, Thomas; Ziswiler, Hans Rudolf; Leib, Stephen (2003). [Nocardia cyriacigeorgici: First report of invasive human infection]. Deutsche medizinische Wochenschrift, 128(19), pp. 1038-1041. Thieme 10.1055/s-2003-39102

Gianinazzi, Christian; Grandgirard, Denis; Imboden, Hans; Egger, Lotti; Meli, Damian N; Bifrare, Yoeng-Delphine; Joss, Philipp; Täuber, Martin G.; Borner, Christoph; Leib, Stephen (2003). Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta neuropathologica, 105(5), pp. 499-507. Springer 10.1007/s00401-003-0672-7

Coumans, Audrey B C; Middelanis, Johannes S; Garnier, Yves; Vaihinger, Hans-Martin; Leib, Stephen; Von Duering, Monika U; Hasaart, Tom H M; Jensen, Arne; Berger, Richard (2003). Intracisternal application of endotoxin enhances the susceptibility to subsequent hypoxic-ischemic brain damage in neonatal rats. Pediatric research, 53(5), pp. 770-775. Nature Publishing Group 10.1203/01.PDR.0000059221.40073.82

Meli, Damian N.; Christen, Stephan; Leib, Stephen L. (2003). Matrix metalloproteinase-9 in pneumococcal meningitis: activation via an oxidative pathway. Journal of infectious diseases, 187(9), pp. 1411-1415. Cary, N.C.: Oxford University Press 10.1086/374644

Kolarova, Anna; Ringer, Ralph; Täuber, Martin G.; Leib, Stephen L. (2003). Blockade of NMDA receptor subtype NR2B prevents seizures but not apoptosis of dentate gyrus neurons in bacterial meningitis in infant rats. BMC neuroscience, 4(21), p. 21. London: BioMed Central 10.1186/1471-2202-4-21

Bifrare, Yoeng-Delphine; Gianinazzi, Christian; Imboden, Hans; Leib, Stephen; Täuber, Martin G. (2003). Bacterial meningitis causes two distinct forms of cellular damage in the hippocampal dentate gyrus in infant rats. Hippocampus, 13(4), pp. 481-488. Wiley-Liss 10.1002/hipo.10142

2002

Williams, Paul L; Leib, Stephen; Kamberi, Perparim; Leppert, David; Sobel, Raymond A; Bifrare, Yoeng-Delphine; Clemons, Karl V; Stevens, David A (2002). Levels of matrix metalloproteinase-9 within cerebrospinal fluid in a rabbit model of coccidioidal meningitis and vasculitis. Journal of infectious diseases, 186(11), pp. 1692-1695. Oxford University Press 10.1086/345365

Echchannaoui, Hakim; Frei, Karl; Schnell, Christian; Leib, Stephen L.; Zimmerli, Werner; Landmann, Regine (2002). Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation. Journal of infectious diseases, 186(6), pp. 798-806. Oxford University Press 10.1086/342845

Remer, Katharina A.; Pfister, Hedi; Fatzer, Rosmarie; Leib, Stephen L.; Jungi, Thomas W. (2002). The role of nitric oxide in Listeria encephalitis of ruminants and in rats intracisternally infected with Listeria monocytogenes. Berliner und Münchener tierärztliche Wochenschrift, 115(7-8), pp. 259-266. Schlütersche

Vonlaufen, Nathalie; Gianinazzi, Christian; Müller, Norbert; Simon, Franziska; Björkman, Camilla; Jungi, Thomas W.; Leib, Stephen L.; Hemphill, Andrew (2002). Infection of organotypic slice cultures from rat central nervous tissue with Neospora caninum: an alternative approach to study host-parasite interactions. International journal for parasitology, 32(5), pp. 533-542. Elsevier 10.1016/S0020-7519(01)00351-4

Müller, Norbert; Vonlaufen, Nathalie Françoise F.; Gianinazzi, Christian; Leib, Stephen L.; Hemphill, Andrew (2002). Application of real-time fluorescent PCR for quantitative assessment of Neospora caninum infections in organotypic slice cultures of rat central nervous system tissue. Journal of clinical microbiology, 40(1), pp. 252-255. American Society for Microbiology 10.1128/JCM.40.1.252-255.2002

Schaper, Manuela; Gergely, Suzanne; Lykkesfeldt, Jens; Zbären, Jakob; Leib, Stephen L.; Täuber, Martin G.; Christen, Stephan (2002). Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis. Journal of neuropathology and experimental neurology, 61(7), pp. 605-13. Hagerstown, Md.: Lippincott Williams & Wilkins

Meli, Damian N.; Christen, Stephan; Leib, Stephen L.; Täuber, Martin G. (2002). Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae. Current opinion in infectious diseases, 15(3), pp. 253-357. Hagerstown, Md.: Wolters Kluwer Lippincott Williams & Wilkins 10.1097/00001432-200206000-00007

Pfister, H.; Remer, K. A.; Brcic, Marija; Fatzer, R.; Christen, Stephan; Leib, Stephen L.; Jungi, Thomas W. (2002). Inducible nitric oxide synthase and nitrotyrosine in listeric encephalitis: a cross-species study in ruminants. Veterinary pathology, 39(2), pp. 190-199. Middleton, Wis.: American College of Veterinary Pathologists 10.1354/vp.39-2-190

2001

Loeffler, Jutta M.; Bodmer, Thomas; Zimmerli, Werner; Leib, Stephen L. (2001). Nocardial brain abscess: observation of treatment strategies and outcome in Switzerland from 1992 to 1999. Infection, 29(6), pp. 337-341. Springer-Medizin-Verlag 10.1007/s15010-001-1147-1

Leppert, David; Lindberg, Raija L.P.; Kappos, Ludwig; Leib, Stephen L. (2001). Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis. Brain research reviews, 36(2-3), pp. 249-257. Elsevier 10.1016/S0165-0173(01)00101-1

Piso, R J; Leib, Stephen L. (2001). [What is your diagnosis? Basal meningitis and rhombencephalitis. Blood culture positive for Listeria monocytogenes]. Praxis - schweizerische Rundschau für Medizin, 90(19), pp. 823-824. Huber

Christen, Stephan; Schaper, Manuela; Lykkesfeldt, Jens; Siegenthaler, Corinne; Bifrare, Yoeng-Delphine; Banic, Staša; Leib, Stephen L.; Täuber, Martin G. (2001). Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment. Free radical biology & medicine, 31(6), pp. 754-762. San Diego, Calif.: Elsevier 10.1016/S0891-5849(01)00642-6

Christen, Stephan; Bifrare, Yeong-Delphine; Siegenthaler, Corinne; Leib, Stephen L.; Täuber, Martin G. (2001). Marked elevation in cortical urate and xanthine oxidoreductase activity in experimental bacterial meningitis. Brain research, 900(2), pp. 244-251. Amsterdam: Elsevier 10.1016/S0006-8993(01)02311-3

Leib, Stephen L.; Clements, John M.; Lindberg, Raija L. P.; Heimgartner, Chris; Loeffler, Jutta M.; Pfister, Luz-Andrea; Täuber, Martin G.; Leppert, David (2001). Inhibition of matrix metalloproteinases and tumour necrosis factor alpha converting enzyme as adjuvant therapy in pneumococcal meningitis. Brain, 124(9), pp. 1734-1742. Oxford: Oxford University Press 10.1093/brain/124.9.1734

Remer, K. A.; Jungi, Thomas W.; Fatzer, R.; Täuber, Martin G.; Leib, Stephen L. (2001). Nitric oxide is protective in listeric meningoencephalitis of rats. Infection and immunity, 69(6), pp. 4086-4093. New York, N.Y.: American Society for Microbiology 10.1128/IAI.69.6.4086-4093.2001

Loeffler, Jutta M.; Ringer, Ralph; Hablützel, Martin; Täuber, Martin G.; Leib, Stephen L. (2001). The free radical scavenger alpha-phenyl-tert-butyl nitrone aggravates hippocampal apoptosis and learning deficits in experimental pneumococcal meningitis. Journal of infectious diseases, 183(2), pp. 247-252. Cary, N.C.: Oxford University Press 10.1086/317921

2000

Leppert, David; Leib, Stephen L.; Grygar, C.; Miller, K. M.; Schaad, U. B.; Holländer, G. A. (2000). Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae. Clinical infectious diseases, 31(1), pp. 80-84. Oxford University Press 10.1086/313922

Leib, Stephen L.; Zimmerli, Werner (2000). Reply. Clinical infectious diseases, 30(5), pp. 837-838. Oxford University Press 10.1086/313779

Pfister, LA; Tureen, JH; Shaw, S; Christen, S; Ferriero, DM; Täuber, MG; Leib, Stephen L. (2000). Endothelin inhibition improves cerebral blood flow and is neuroprotective in pneumococcal meningitis. Annals of neurology, 47(3), pp. 329-335. Hoboken, N.J.: Wiley-Blackwell 10.1002/1531-8249(200003)47:3<329::AID-ANA8>3.3.CO;2-I

Leib, Stephen L.; Täuber, MG (2000). [In search of strategies for preventing brain damage as a sequela of bacterial meningitis]. Schweizerische medizinische Wochenschrift, 130(24), pp. 928-35. Basel: B. Schwabe & Co.

Auer, Marc; Pfister, Luz-Andrea; Leppert, David; Täuber, Martin G.; Leib, Stephen L. (2000). Effects of clinically used antioxidants in experimental pneumococcal meningitis. Journal of infectious diseases, 182(1), pp. 347-350. Cary, N.C.: Oxford University Press 10.1086/315658

Leib, Stephen L.; Leppert, David; Clements, John; Täuber, Martin G. (2000). Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis. Infection and immunity, 68(2), pp. 615-620. New York, N.Y.: American Society for Microbiology 10.1128/IAI.68.2.615-620.2000

1999

Leib, Stephen; Täuber, Martin G. (1999). [Meningitis (I)--differential diagnosis; aseptic and chronic meningitis]. Therapeutische Umschau, 56(11), pp. 631-639. Huber 10.1024/0040-5930.56.11.631

Leib, Stephen; Täuber, Martin G. (1999). Pathogenesis of bacterial meningitis. Infectious disease clinics of North America, 13(3), pp. 527-548. Elsevier 10.1016/S0891-5520(05)70093-3

Leib, Stephen; Boscacci, R; Gratzl, O; Zimmerli, W (1999). Predictive value of cerebrospinal fluid (CSF) lactate level versus CSF/blood glucose ratio for the diagnosis of bacterial meningitis following neurosurgery. Clinical infectious diseases, 29(1), pp. 69-74. Oxford University Press 10.1086/520184

Garzoni, C; Leib, Stephen; Zimmerli, W (1999). [Pneumococcal meningitis as a complication of maxillary sinusitis. Purulent conjunctivitis is linked to maxillary sinusitis]. Praxis - schweizerische Rundschau für Medizin, 88(11), pp. 491-495. Huber

Leib, Stephen L.; Täuber, Martin G. (1999). [Meningitis (II)--acute bacterial meningitis]. Therapeutische Umschau, 56(11), pp. 640-646. Bern: Huber 10.1024/0040-5930.56.11.640

Michelet, C; Leib, Stephen; Bentue-Ferrer, D; Täuber, Martin G. (1999). Comparative efficacies of antibiotics in a rat model of meningoencephalitis due to Listeria monocytogenes. Antimicrobial agents and chemotherapy, 43(7), pp. 1651-1656. Washington, D.C.: American Society for Microbiology

1998

Leib, Stephen L.; Kim, Young S.; Black, Stephen M.; Tureen, Jay H.; Täuber, Martin G. (1998). Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. Journal of infectious diseases, 177(3), pp. 692-700. Cary, N.C.: Oxford University Press 10.1086/514226

1997

Bogdan, I.; Leib, Stephen L.; Bergeron, M.; Chow, L.; Täuber, Martin G. (1997). Tumor necrosis factor-alpha contributes to apoptosis in hippocampal neurons during experimental group B streptococcal meningitis. Journal of infectious diseases, 176(3), pp. 693-697. Cary, N.C.: Oxford University Press 10.1086/514092

1996

Leib, Stephen; Kim, Y S; Chow, L L; Sheldon, R A; Täuber, Martin G. (1996). Reactive oxygen intermediates contribute to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B streptococci. Journal of clinical investigation, 98(11), pp. 2632-2639. American Society for Clinical Investigation 10.1172/JCI119084

Leib, Stephen; Kim, Y S; Black, S M; Ferriero, D M; Täuber, Martin G. (1996). Detrimental effect of nitric oxide inhibition in experimental bacterial meningitis. Annals of neurology, 39(4), pp. 555-556. Wiley-Blackwell 10.1002/ana.410390422

Leib, Stephen; Kim, YS; Ferriero, DM; Täuber, Martin G. (1996). Neuroprotective effect of excitatory amino acid antagonist kynurenic acid in experimental bacterial meningitis. Journal of infectious diseases, 173(1), pp. 166-171. Cary, N.C.: Oxford University Press 10.1093/infdis/173.1.166

1994

Leib, Stephen (1994). [A case from practice (300). Lambliasis; possibly 2-year-old chronic infection. Maculopapillary pruritic exanthema of the hairy scalp and the sternum; seborrheic dermatitis; skin reaction to lambliasis? Horseshoe kidney]. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis, 83(29-30), pp. 836-837.

Leib, Stephen (1994). [A case from practice (305). Recurrent erysipelas--tinea pedis et unginum--chronic venous insufficiency]. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis, 83(39), pp. 1089-1090.

1993

Böni, J; Emmerich, B S; Leib, Stephen; Wiestler, O D; Schüpbach, J; Kleihues, P (1993). PCR identification of HIV-1 DNA sequences in brain tissue of patients with AIDS encephalopathy. Neurology, 43(9), pp. 1813-1817. Lippincott Williams & Wilkins

Schlienger, R. G.; Haefeli, W. E.; Bircher, A.; Leib, Stephen L.; Lüscher, T. F. (1993). [Drug-induced Stevens-Johnson syndrome in a patient with AIDS]. Schweizerische Rundschau fuer Medizin Praxis, 82(33), pp. 888-892.

1992

Wiestler, O. D.; Leib, Stephen L.; Brüstle, O.; Spiegel, H.; Kleihues, P. (1992). Neuropathology and pathogenesis of HIV encephalopathies. Acta histochemica, 42(Suppl.), pp. 107-114. Elsevier

Brüstle, O.; Spiegel, H.; Leib, Stephen L.; Finn, T.; Stein, H.; Kleihues, P.; Wiestler, O. D. (1992). Distribution of human immunodeficiency virus (HIV) in the CNS of children with severe HIV encephalomyelopathy. Acta neuropathologica, 84(1), pp. 24-31. Springer

1991

Kleihues, P.; Leib, Stephen L.; Strittmatter, C.; Wiestler, O. D.; Lang, W. (1991). HIV encephalopathy: incidence, definition and pathogenesis. Results of a Swiss collaborative study. Acta pathologica japonica, 41(3), pp. 197-205.

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