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Wegner, Fanny; Cabrera-Gil, Blanca; Tanguy, Araud; Beckmann, Christiane; Beerenwinkel, Niko; Bertelli, Claire; Carrara, Matteo; Cerutti, Lorenzo; Chen, Chaoran; Cordey, Samuel; Dumoulin, Alexis; du Plessis, Louis; Friedli, Marc; Gerth, Yannick; Greub, Gilbert; Härri, Adrian; Hirsch, Hans; Howald, Cedric; Huber, Michael; Imhof, Alexander; ... (2024). How much should we sequence? An analysis of the Swiss SARS-CoV-2 surveillance effort. Microbiology spectrum, 12(5), e0362823. American Society for Microbiology 10.1128/spectrum.03628-23
Lux, Janine; Portmann, Hannah; Sánchez García, Lucia; Erhardt, Maria; Holivololona, Lalaina; Laloli, Laura; Licheri, Manon F; Gallay, Clement; Hoepner, Robert; Croucher, Nicholas J; Straume, Daniel; Veening, Jan-Willem; Dijkman, Ronald; Heller, Manfred; Grandgirard, Denis; Leib, Stephen L; Hathaway, Lucy J (2024). Klebsiella pneumoniae peptide hijacks a Streptococcus pneumoniae permease to subvert pneumococcal growth and colonization. Communications biology, 7(425) Springer Nature 10.1038/s42003-024-06113-9
Terrazos Miani, Miguel A; Borcard, Loïc; Gempeler, Sonja; Baumann, Christian; Bittel, Pascal; Leib, Stephen L; Neuenschwander, Stefan; Ramette, Alban Nicolas (2024). NASCarD (Nanopore Adaptive Sampling with Carrier DNA): A Rapid, PCR-Free Method for SARS-CoV-2 Whole-Genome Sequencing in Clinical Samples. Pathogens, 13(1) MDPI AG 10.3390/pathogens13010061
Abbuehl, Lena S; Branca, Mattia; Ungureanu, Anamaria; Federspiel, Andrea; Leib, Stephen L; Bassetti, Claudio L. A.; Hakim, Arsany; Dietmann, Anelia (2024). Magnetic resonance imaging in acute meningoencephalitis of viral and unknown origin: frequent findings and prognostic potential. Frontiers in neurology, 15 Frontiers Media S.A. 10.3389/fneur.2024.1359437
Kronenberg, Andreas; Gasser, Michael; Plüss-Suard, Catherine; Friedli, Olivier; Leib, Stephen (2024). Für einen besseren Umgang mit Antibiotika. Schweizerische Ärztezeitung, 105(04), pp. 29-33. EMH Schweizerischer Ärzteverlag AG 10.4414/saez.2024.1288111951
Schwitter, Janine; Branca, Mattia; Bicvic, Antonela; Abbühl, Lena S.; Suter-Riniker, Franziska; Leib, Stephen L.; Dietmann, Anelia (2024). Long-term sequelae after viral meningitis and meningoencephalitis are frequent, even in mildly affected patients, a prospective observational study. Frontiers in neurology, 15 Frontiers Media S.A. 10.3389/fneur.2024.1411860
Chiffi, Gabriele; Grandgirard, Denis; Leib, Stephen L; Chrdle, Aleš; Růžek, Daniel (2023). Tick-borne encephalitis: A comprehensive review of the epidemiology, virology, and clinical picture. Reviews in medical virology, 33(5), e2470. Wiley 10.1002/rmv.2470
Raemy, Samuel; Casanova, Carlo; Baldan, Rossella; Barreto, Erin; Tande, Aaron J; Endimiani, Andrea; Leib, Stephen L; Fischer, Urs; Sendi, Parham (2023). Penicillin-Susceptible Streptococcus pneumoniae Meningitis in Adults: Does the Ceftriaxone Dosing Matter? Antibiotics, 12(5) MDPI 10.3390/antibiotics12050878
Neves, Aitana; Walther, Daniel; Martin-Campos, Trinidad; Barbie, Valerie; Bertelli, Claire; Blanc, Dominique; Bouchet, Gérard; Erard, Frédéric; Greub, Gilbert; Hirsch, Hans H; Huber, Michael; Kaiser, Laurent; Leib, Stephen L; Leuzinger, Karoline; Lazarevic, Vladimir; Mäusezahl, Mirjam; Molina, Jorge; Neher, Richard A; Perreten, Vincent; Ramette, Alban; ... (2023). The Swiss Pathogen Surveillance Platform - towards a nation-wide One Health data exchange platform for bacterial, viral and fungal genomics and associated metadata. Microbial genomics, 9(5) Microbiology Society 10.1099/mgen.0.001001
Saegerman, Claude; Humblet, Marie-France; Leandri, Marc; Gonzalez, Gaëlle; Heyman, Paul; Sprong, Hein; L'Hostis, Monique; Moutailler, Sara; Bonnet, Sarah I; Haddad, Nadia; Boulanger, Nathalie; Leib, Stephen L; Hoch, Thierry; Thiry, Etienne; Bournez, Laure; Kerlik, Jana; Velay, Aurélie; Jore, Solveig; Jourdain, Elsa; Gilot-Fromont, Emmanuelle; ... (2023). First Expert Elicitation of Knowledge on Possible Drivers of Observed Increasing Human Cases of Tick-Borne Encephalitis in Europe. Viruses, 15(3) MDPI 10.3390/v15030791
Ackermann-Gäumann, Rahel; Eyer, Claudia; Vock, Michael; Gowland, Peter; Tinguely, Caroline; Leib, Stephen L; Bori, Mauro; Buser, Andreas; Fontana, Stefano; Thierbach, Jutta; Weingand, Tina; Niederhauser, Christoph (2023). Prevalence of anti-tick-borne encephalitis virus (TBEV) antibodies in Swiss blood donors in 2014-2015. Blood transfusion, 21(2), pp. 100-109. SIMTI Servizi Srl 10.2450/2022.0099-22
Müller, Annelies; Lekhuleni, Cebile; Hupp, Sabrina; du Plessis, Mignon; Holivololona, Lalaina; Babiichuk, Eduard; Leib, Stephen L.; Grandgirard, Denis; Iliev, Asparouh I.; von Gottberg, Anne; Hathaway, Lucy J. (2023). Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes. Frontiers in cellular and infection microbiology, 12 Frontiers 10.3389/fcimb.2022.1106063
Le, Ngoc Dung; Ricci, Susanna; Grandgirard, Denis; Leib, Stephen L (2023). Experimental meningitis by Streptococcus pneumoniae and Neisseria meningitidis in rodents. In: Handbook of Animal Models in Neurological Disorders (pp. 329-341). Elsevier 10.1016/B978-0-323-89833-1.00050-1
Ernst, Alexander; Piragyte, Indre; MP, Ayisha Marwa; Le, Ngoc Dung; Grandgirard, Denis; Leib, Stephen L.; Oates, Andrew; Mercader, Nadia (2023). Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform. Scientific reports, 13(1), p. 17037. Springer Nature 10.1038/s41598-023-43911-3
Terrazos Miani, Miguel A.; Borcard, Loïc; Gempeler, Sonja; Baumann, Christian; Bittel, Pascal; Leib, Stephen L.; Neuenschwander, Stefan; Ramette, Alban (2023). NASCarD (Nanopore Adaptive Sampling with Carrier DNA): A rapid, PCR-free method for whole genome sequencing of pathogens in clinical samples (Submitted) (medRxiv). Cold Spring Harbor Laboratory 10.1101/2023.03.10.23287094
Grädel, C; Ireddy, N R; Koch, M C; Baumann, C; Terrazos Miani, M A; Barbani, M T; Steinlin-Schopfer, J; Suter-Riniker, F; Leib, S L; Ramette, A (2022). Genome Sequences of Rare Human Enterovirus Genotypes Recovered from Clinical Respiratory Samples in Bern, Switzerland. Microbiology resource announcements, 11(9), e0027622. American Society for Microbiology 10.1128/mra.00276-22
Zimmermann, Josua; Friedli, Nicole; Bavato, Francesco; Stämpfli, Philipp; Coray, Rebecca; Baumgartner, Markus R; Grandgirard, Denis; Leib, Stephen L; Opitz, Antje; Seifritz, Erich; Stock, Ann-Kathrin; Beste, Christian; Cole, David M; Quednow, Boris B (2022). White matter alterations in chronic MDMA use: Evidence from diffusion tensor imaging and neurofilament light chain blood levels. NeuroImage: Clinical, 36, p. 103191. Elsevier 10.1016/j.nicl.2022.103191
Chiffi, Gabriele; Grandgirard, Denis; Stöckli, Sabrina; Valente, Luca G; Adamantidis, Antoine; Leib, Stephen L (2022). Tick-borne encephalitis affects sleep-wake behavior and locomotion in infant rats. Cell & bioscience, 12(1), p. 121. BioMed Central 10.1186/s13578-022-00859-7
Le, Ngoc Dung; Steinfort, Marel; Grandgirard, Denis; Maleska, Aleksandra; Leppert, David; Kuhle, Jens; Leib, Stephen L (2022). The CCR5 antagonist maraviroc exerts limited neuroprotection without improving neurofunctional outcome in experimental pneumococcal meningitis. Scientific reports, 12(1), p. 12945. Springer Nature 10.1038/s41598-022-17282-0
Guse, Kirsten; Hagemann, Nina; Thiele, Lisa; Remlinger, Jana; Salmen, Anke; Hoepner, Robert; Keller, Irene; Meyer, Patricia; Grandgirard, Denis; Leib, Stephen; Vassella, Erik; Locatelli, Giuseppe; Hermann, Dirk M; Chan, Andrew Hao-Kuang (2022). CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells. Neurology: neuroimmunology & neuroinflammation, 9(4) Wolters Kluwer Health 10.1212/NXI.0000000000001168
Ullmann, Irina; Aregger, Andrea; Leib, Stephen L; Zimmerli, Stefan (2022). Caspofungin Cerebral Penetration and Therapeutic Efficacy in Experimental Cerebral Aspergillosis. Microbiology spectrum, 10(3), e0275321. American Society for Microbiology 10.1128/spectrum.02753-21
Prazak, Josef; Valente, Luca; Iten, Manuela; Federer, Lea; Grandgirard, Denis; Soto, Sara; Resch, Gregory; Leib, Stephen L.; Jakob, Stephan M.; Haenggi, Matthias; Cameron, David R.; Que, Yok-Ai (2022). Benefits of aerosolized phages for the treatment of pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA): an experimental study in rats. The journal of infectious diseases, 225(8), pp. 1452-1459. Oxford University Press 10.1093/infdis/jiab112
Borcard, Loïc; Gempeler, Sonja; Terrazos Miani, Miguel A; Baumann, Christian; Grädel, Carole; Dijkman, Ronald; Suter-Riniker, Franziska; Leib, Stephen L; Bittel, Pascal; Neuenschwander, Stefan; Ramette, Alban (2022). Investigating the Extent of Primer Dropout in SARS-CoV-2 Genome Sequences During the Early Circulation of Delta Variants. Frontiers in Virology, 2 Frontiers 10.3389/fviro.2022.840952
Wegner, Fanny; Roloff, Tim; Huber, Michael; Cordey, Samuel; Ramette, Alban; Gerth, Yannick; Bertelli, Claire; Stange, Madlen; Seth-Smith, Helena M B; Mari, Alfredo; Leuzinger, Karoline; Cerutti, Lorenzo; Harshman, Keith; Xenarios, Ioannis; Le Mercier, Philippe; Bittel, Pascal; Neuenschwander, Stefan; Opota, Onya; Fuchs, Jonas; Panning, Marcus; ... (2022). External quality assessment of SARS-CoV-2-sequencing: An ESGMD-SSM pilot trial across 15 European laboratories. Journal of clinical microbiology, 60(1), e0169821. American Society for Microbiology 10.1128/JCM.01698-21
Chiffi, Gabriele; Grandgirard, Denis; Sendi, Parham; Dietmann, Anelia; Bassetti, Claudio L. A.; Leib, Stephen (2022). Sleep-Wake and Circadian Disorders after Tick-Borne Encephalitis. Microorganisms, 10(2), p. 304. MDPI 10.3390/microorganisms10020304
Askarian, Mehrdad; Semenov, Aleksandr; Llopis, Ferran; Rubulotta, Francesca; Dragovac, Gorana; Pshenichnaya, Natalia; Assadian, Ojan; Ruch, Yvon; Shayan, Zahra; Padilla Fortunatti, Cristobal; Lucey, Daniel; Almohaizeie, Abdullah; Kamal, Abu Hena Mostafa; Ogunshe, Adenike; Konkayev, Aidos; Beg, Asim; Primerano, Enzo; Amer, Fatma; Kumari Pilli, Hema Prakash; Hung, Ivan; ... (2022). The COVID-19 vaccination acceptance/hesitancy rate and its determinants among healthcare workers of 91 Countries: A multicenter cross-sectional study. EXCLI journal, 21, pp. 93-103. 10.17179/excli2021-4439
Hirzel, Cédric; Grandgirard, Denis; Surial, Bernard; Wider, Manon F.; Leppert, David; Kuhle, Jens; Walti, Laura N.; Schefold, Joerg C.; Spinetti, Thibaud; Suter-Riniker, Franziska; Dijkman, Ronald; Leib, Stephen L (2022). Neuro-axonal injury in COVID-19: the role of systemic inflammation and SARS-CoV-2 specific immune response. Therapeutic advances in neurological disorders, 15, p. 17562864221080528. Sage 10.1177/17562864221080528
Valente, Luca G; Le, Ngoc Dung; Pitton, Melissa; Chiffi, Gabriele; Grandgirard, Denis; Jakob, Stephan M; Cameron, David R; Resch, Grégory; Que, Yok-Ai; Leib, Stephen L (2022). Efficacy assessment of a novel endolysin PlyAZ3aT for the treatment of ceftriaxone-resistant pneumococcal meningitis in an infant rat model. PLoS ONE, 17(4), e0266928. Public Library of Science 10.1371/journal.pone.0266928
Hammer, Helly; Hoepner, Robert; Friedli, Christoph; Leib, Stephen L; Suter-Riniker, Franziska; Diem, Lara; Kamber, Nicole; Chan, Andrew; Salmen, Anke; Kamm, Christian P (2022). Comparison of mRNA Vaccinations with BNT162b2 or mRNA-1273 in Anti-CD20-Treated Multiple Sclerosis Patients. Vaccines, 10(6), p. 922. MDPI 10.3390/vaccines10060922
Akello, Joyce Odeke; Kamgang, Richard; Barbani, Maria Teresa; Suter-Riniker, Franziska; Aebi, Christoph; Beuret, Christian; Paris, Daniel H.; Leib, Stephen L.; Ramette, Alban (2021). Genomic analyses of human adenoviruses unravel novel recombinant genotypes associated with severe infections in pediatric patients. Scientific reports, 11(1), p. 24038. Springer Nature 10.1038/s41598-021-03445-y
Ungureanu, Anamaria; van der Meer, Julia; Bicvic, Antonela; Abbuehl, Lena; Chiffi, Gabriele; Jaques, Léonore; Suter-Riniker, Franziska; Leib, Stephen L.; Bassetti, Claudio L.A.; Dietmann, Anelia (2021). Meningitis, meningoencephalitis and encephalitis in Bern: an observational study of 258 patients. BMC neurology, 21(1), p. 474. BioMed Central 10.1186/s12883-021-02502-3
Casanova, Carlo; Küffer, Marianne; Leib, Stephen L.; Hilty, Markus (2021). Re-emergence of invasive pneumococcal disease (IPD) and increase of serotype 23B after easing of COVID-19 measures, Switzerland, 2021. Emerging microbes & infections, 10(1), pp. 2202-2204. Taylor & Francis 10.1080/22221751.2021.2000892
Valente, Luca G.; Federer, Lea; Iten, Manuela; Grandgirard, Denis; Leib, Stephen L.; Jakob, Stephan M.; Haenggi, Matthias; Cameron, David R.; Que, Yok-Ai; Prazak, Josef (2021). Searching for synergy: combining systemic daptomycin treatment with localised phage therapy for the treatment of experimental pneumonia due to MRSA. BMC research notes, 14(1), p. 381. Biomed Central 10.1186/s13104-021-05796-1
Jebbawi, Fadi; Bellanger, Anne-Pauline; Lundström-Stadelmann, Britta; Rufener, Reto; Dosch, Michel; Goepfert, Christine; Gottstein, Bruno; Millon, Laurence; Grandgirard, Denis; Leib, Stephen L.; Beldi, Guido; Wang, Junhua (2021). Innate and adaptive immune responses following PD-L1 blockade in treating chronic murine alveolar echinococcosis. Parasite immunology, 43(8), e12834. Wiley 10.1111/pim.12834
Oyewole, Oluwaseun Rume-Abiola; Lang, Phung; Albrich, Werner C.; Wissel, Kerstin; Leib, Stephen L.; Casanova, Carlo; Hilty, Markus (2021). The Impact of Pneumococcal Conjugate Vaccine (PCV) Coverage Heterogeneities on the Changing Epidemiology of Invasive Pneumococcal Disease in Switzerland, 2005–2019. Microorganisms, 9(5) MDPI 10.3390/microorganisms9051078
Engelter, Stefan T; Traenka, Christopher; Gensicke, Henrik; Schaedelin, Sabine A; Luft, Andreas R; Goeggel Simonetti, Barbara; Fischer, Urs; Michel, Patrik; Sirimarco, Gaia; Kägi, Georg; Vehoff, Jochen; Nedeltchev, Krassen; Kahles, Timo; Kellert, Lars; Rosenbaum, Sverre; von Rennenberg, Regina; Sztajzel, Roman; Leib, Stephen L; Jung, Simon; Gralla, Jan; ... (2021). Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. The lancet. Neurology, 20(5), pp. 341-350. Elsevier 10.1016/S1474-4422(21)00044-2
Goncalves Cabecinhas, Ana Rita; Roloff, Tim; Stange, Madlen; Bertelli, Claire; Huber, Michael; Ramette, Alban; Chen, Chaoran; Nadeau, Sarah; Gerth, Yannick; Yerly, Sabine; Opota, Onya; Pillonel, Trestan; Schuster, Tobias; Metzger, Cesar M J A; Sieber, Jonas; Bel, Michael; Wohlwend, Nadia; Baumann, Christian; Koch, Michel C.; Bittel, Pascal; ... (2021). SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021-Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing. Microorganisms, 9(4), p. 677. MDPI 10.3390/microorganisms9040677
Brigger, D.; Horn, M. P.; Pennington, L. F.; Powell, A. E.; Siegrist, D.; Weber, B.; Engler, O.; Piezzi, V.; Damonti, L.; Iseli, P.; Hauser, C.; Froehlich, T. K.; Villiger, P. M.; Bachmann, Martin F.; Leib, S. L.; Bittel, P.; Fiedler, M.; Largiadèr, C.; Marschall, J.; Stalder, H.; ... (2021). Accuracy of serological testing for SARS-CoV-2 antibodies: first results of a large mixed-method evaluation study. Allergy, 76(3), pp. 853-865. Wiley 10.1111/all.14608
Grüter, Basil E.; Wanderer, Stefan; Strange, Fabio; Boillat, Gwendoline; Täschler, Dominik; Rey, Jeannine; Croci, Davide M; Grandgirard, Denis; Leib, Stephen; von Gunten, Michael; Di Santo, Stefano; Widmer, Hans Rudolf; Remonda, Luca; Andereggen, Lukas; Nevzati, Edin; Coluccia, Daniel; Fandino, Javier; Marbacher, Serge (2021). Patterns of Neointima Formation After Coil or Stent Treatment in a Rat Saccular Sidewall Aneurysm Model. Stroke, 52(3), pp. 1043-1052. American Heart Association 10.1161/STROKEAHA.120.032255
Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355
Friedli, Christoph; Diem, Lara; Hammer, Helly; Kamber, Nicole; Suter-Riniker, Franziska; Leib, Stephen; Chan, Andrew; Hirzel, Cédric; Hoepner, Robert; Salmen, Anke (2021). Negative SARS-CoV2-antibodies after positive COVID-19-PCR nasopharyngeal swab in patients treated with anti-CD20 therapies. Therapeutic advances in neurological disorders, 14, p. 17562864211016641. Sage 10.1177/17562864211016641
Erni, Silvia T.; Gill, John C.; Palaferri, Carlotta; Fernandes, Gabriella; Buri, Michelle; Lazarides, Katherine; Grandgirard, Denis; Edge, Albert S. B.; Leib, Stephen; Roccio, Marta (2021). Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors. Frontiers in cell and developmental biology, 9(2256) Frontiers 10.3389/fcell.2021.710159
Valente, Luca G.; Pitton, Melissa; Fürholz, Monika; Oberhaensli, Simone; Bruggmann, Rémy; Leib, Stephen L.; Jakob, Stephan M.; Resch, Grégory; Que, Yok-Ai; Cameron, David R. (2021). Isolation and characterization of bacteriophages from the human skin microbiome that infect Staphylococcus epidermidis. FEMS Microbes, 2 Oxford University Press 10.1093/femsmc/xtab003
Borcard, Loïc; Gempeler, Sonja; Terrazos Miani, Miguel A.; Baumann, Christian; Grädel, Carole; Dijkman, Ronald; Suter-Riniker, Franziska; Leib, Stephen L; Bittel, Pascal; Neuenschwander, Stefan; Ramette, Alban (2021). Investigating the biological and technical origins of unknown bases in the S region of the SARS-CoV-2 Delta variant genome sequences (medRxiv). Cold Spring Harbor Laboratory 10.1101/2021.09.09.21262951
Akello, Joyce Odeke; Kamgang, Richard; Barbani, Maria Teresa; Suter-Riniker, Franziska; Aebi, Christoph; Beuret, Christian; Paris, Daniel H.; Leib, Stephen L.; Ramette, Alban (2021). Genomic analyses of human adenoviruses unravel novel recombinant genotypes associated with severe infections in pediatric patients (medRxiv). Cold Spring Harbor Laboratory 10.1101/2021.08.01.21261368
Wasimuddin, Wasimuddin; Schlaeppi, Klaus; Ronchi, Francesca; Leib, Stephen L.; Erb, Matthias; Ramette, Alban (2020). Evaluation of primer pairs for microbiome profiling from soils to humans within the One Health framework. Molecular ecology resources, 20(6), pp. 1558-1571. Wiley 10.1111/1755-0998.13215
Muri, Lukas; Oberhänsli, Simone; Buri, Michelle; Le, Ngoc Dung; Grandgirard, Denis; Bruggmann, Rémy; Müri, René M.; Leib, Stephen L. (2020). Repetitive transcranial magnetic stimulation activates glial cells and inhibits neurogenesis after pneumococcal meningitis. PLoS ONE, 15(9), e0232863. Public Library of Science 10.1371/journal.pone.0232863
Brigger, Daniel; Riether, Carsten; van Brummelen, Robin; Mosher, Kira I; Shiu, Alicia; Ding, Zhaoqing; Zbären, Noemi; Gasser, Pascal; Guntern, Pascal; Yousef, Hanadie; Castellano, Joseph M; Storni, Federico; Graff-Radford, Neill; Britschgi, Markus; Grandgirard, Denis; Hinterbrandner, Magdalena; Siegrist, Mark; Moullan, Norman; Hofstetter, Wilhelm; Leib, Stephen L.; ... (2020). Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nature metabolism, 2(8), pp. 688-702. Springer Nature 10.1038/s42255-020-0228-3
Grädel, Carole; Terrazos Miani, Miguel A.; Baumann, Christian; Barbani, Maria Teresa; Neuenschwander, Stefan; Leib, Stephen L.; Suter-Riniker, Franziska; Ramette, Alban (2020). Whole-Genome Sequencing of Human Enteroviruses from Clinical Samples by Nanopore Direct RNA Sequencing. Viruses, 12(8) MDPI 10.3390/v12080841
Prazák, Josef; Valente, Luca; Iten, Manuela; Grandgirard, Denis; Leib, Stephen; Jakob, Stephan M.; Hänggi, Matthias; Que, Yok-Ai; Cameron, David R. (2020). Nebulized Bacteriophages for Prophylaxis of Experimental Ventilator-Associated Pneumonia Due to Methicillin-Resistant Staphylococcus aureus. Critical care medicine, 48(7), pp. 1042-1046. Wolters Kluwer Health 10.1097/CCM.0000000000004352
Egli, Adrian; Battegay, Manuel; Büchler, Andrea C; Bühlmann, Peter; Calandra, Thierry; Eckert, Philippe; Furrer, Hansjakob; Greub, Gilbert; Jakob, Stephan M.; Kaiser, Laurent; Leib, Stephen L.; Marsch, Stephan; Meinshausen, Nicolai; Pagani, Jean-Luc; Pugin, Jerome; Rätsch, Gunnar; Schrenzel, Jacques; Schüpbach, Reto; Siegemund, Martin; Zamboni, Nicola; ... (2020). SPHN/PHRT: Forming a Swiss-Wide Infrastructure for Data-Driven Sepsis Research. Studies in health technology and informatics, 270, pp. 1163-1167. IOS Press 10.3233/SHTI200346
Akello, Joyce Odeke; Leib, Stephen L.; Engler, Olivier; Beuret, Christian (2020). Evaluation of Viral RNA Recovery Methods in Vectors by Metagenomic Sequencing. Viruses, 12(5) MDPI 10.3390/v12050562
Meyer, Patricia; Grandgirard, Denis; Lehner, Marika; Haenggi, Matthias; Leib, Stephen (2020). Grafted neural progenitor cells persist in the injured site and differentiate neuronally in a rodent model of cardiac arrest-induced global brain ischemia. Stem cells and development, 29(9), pp. 574-585. Mary Ann Liebert 10.1089/scd.2019.0190
Akello, Joyce Odeke; Kamgang, Richard; Barbani, Maria Teresa; Suter-Riniker, Franziska; Leib, Stephen L; Ramette, Alban (2020). Epidemiology of Human Adenoviruses: A 20-Year Retrospective Observational Study in Hospitalized Patients in Bern, Switzerland. Clinical epidemiology, 12, pp. 353-366. Dove Medical Press 10.2147/CLEP.S246352
Neuenschwander, Stefan Moritz; Terrazos Miani, Miguel Angel; Amlang, Heiko; Perroulaz, Carmen; Bittel, Pascal; Casanova, Carlo; Droz, Sara; Flandrois, Jean-Pierre; Leib, Stephen L.; Suter-Riniker, Franziska; Ramette, Alban (2020). A Sample-to-Report Solution for Taxonomic Identification of Cultured Bacteria in the Clinical Setting Based on Nanopore Sequencing. Journal of clinical microbiology, 58(6) American Society for Microbiology 10.1128/JCM.00060-20
Brackmann, Maximilian; Leib, Stephen; Tonolla, Mauro; Schürch, Nadia; Wittwer, Matthias (2020). Antimicrobial resistance Classification using MALDI-TOF-MS is not that easy: Lessons from vancomycin-resistant Enterococcus faecium. Clinical microbiology and infection, 26(3), pp. 391-393. Elsevier 10.1016/j.cmi.2019.10.027
Le, Ngoc Dung; Muri, Lukas; Grandgirard, Denis; Kuhle, Jens; Leppert, David; Leib, Stephen L. (2020). Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis. Journal of neuroinflammation, 17(1), p. 293. BioMed Central 10.1186/s12974-020-01966-3
Zbinden, Florian R.; De Ste Croix, Megan; Grandgirard, Denis; Haigh, Richard D; Vacca, Irene; Zamudio, Roxana; Goodall, Emily C A; Stephan, Roger; Oggioni, Marco R; Leib, Stephen L. (2020). Pathogenic Differences of Type 1 Restriction-Modification Allele Variants in Experimental Listeria monocytogenes Meningitis. Frontiers in cellular and infection microbiology, 10, p. 590657. Frontiers 10.3389/fcimb.2020.590657
Pan, Steven D.; Grandgirard, Denis; Leib, Stephen L. (2020). Adjuvant Cannabinoid Receptor Type 2 Agonist Modulates the Polarization of Microglia Towards a Non-Inflammatory Phenotype in Experimental Pneumococcal Meningitis. Frontiers in cellular and infection microbiology, 10 Frontiers 10.3389/fcimb.2020.588195
Rosser, Christian; Sager, Fritz; Leib, Stephen L. (2020). Six Recommendations to Build Legitimacy for Translational Research Organizations. Frontiers in medicine, 7, p. 586177. Frontiers 10.3389/fmed.2020.586177
Wasimuddin, Wasimuddin; Schlaeppi, Klaus; Ronchi, Francesca; Leib, Stephen L.; Erb, Matthias; Ramette, Alban (15 November 2019). Evaluation of primer pairs for microbiome profiling across a food chain from soils to humans within the One Health framework (bioRxiv). Cold Spring Harbor Laboratory 10.1101/843144
Prazak, Josef; Iten, Manuela; Cameron, David Robert; Save, Jonathan Florian; Grandgirard, Denis; Resch, Gregory; Göpfert, Christine; Leib, Stephen L.; Takala, Jukka; Jakob, Stephan; Que, Yok-Ai; Hänggi, Matthias (2019). Bacteriophages Improve Outcome in Experimental Staphylococcus Aureus Ventilator Associated Pneumonia. American journal of respiratory and critical care medicine, 200(9), pp. 1126-1133. American Lung Association 10.1164/rccm.201812-2372OC
Grüter, Basil Erwin; Täschler, Dominik; Strange, Fabio; Rey, Jeannine; von Gunten, Michael; Grandgirard, Denis; Leib, Stephen; Remonda, Luca; Widmer, Hans Rudolf; Nevzati, Edin; Fandino, Javier; Marbacher, Serge; Coluccia, Daniel (2019). Testing bioresorbable stent feasibility in a rat aneurysm model. Journal of neurointerventional surgery, 11(10), pp. 1050-1054. BMJ Publishing Group 10.1136/neurintsurg-2018-014697
Grädel, Carole; Terrazos Miani, Miguel Angel; Barbani, Maria Teresa; Leib, Stephen L.; Suter-Riniker, Franziska; Ramette, Alban (2019). Rapid and Cost-Efficient Enterovirus Genotyping from Clinical Samples Using Flongle Flow Cells. Genes, 10(9) MDPI 10.3390/genes10090659
Muri, Lukas Kilian; Leppert, David; Grandgirard, Denis; Leib, Stephen (2019). MMPs and ADAMs in neurological infectious diseases and multiple sclerosis. Cellular and molecular life sciences : CMLS, 76(16), pp. 3097-3116. Springer 10.1007/s00018-019-03174-6
Muri, Lukas Kilian; Le, Ngoc Dung; Zemp, Jonas; Grandgirard, Denis; Leib, Stephen L. (2019). Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis. Journal of neuroinflammation, 16(1), p. 156. BioMed Central 10.1186/s12974-019-1549-6
Muri, Lukas; Perny, Michael; Zemp, Jonas; Grandgirard, Denis; Leib, Stephen L. (2019). Combining Ceftriaxone with Doxycycline and Daptomycin Reduces Mortality, Neuroinflammation, Brain Damage and Hearing Loss in Infant Rat Pneumococcal Meningitis. Antimicrobial agents and chemotherapy, 63(7) American Society for Microbiology 10.1128/AAC.00220-19
Hupp, Sabrina; Grandgirard, Denis; Mitchell, Timothy J.; Leib, Stephen; Hathaway, Lucy Jane; Iliev, Asparouh I. (2019). Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia. Journal of neuroinflammation, 16(1), p. 105. BioMed Central 10.1186/s12974-019-1491-7
Ackermann-Gäumann, Rahel; Eyer, Claudia; Leib, Stephen; Niederhauser-Lüthi, Christoph (2019). Comparison of Four Commercial IgG-Enzyme-Linked Immunosorbent Assays for the Detection of Tick-Borne Encephalitis Virus Antibodies. Vector borne and zoonotic diseases, 19(5), pp. 358-364. Mary Ann Liebert 10.1089/vbz.2018.2359
Colicchio, Roberta; Pagliuca, Chiara; Ricci, Susanna; Scaglione, Elena; Grandgirard, Denis; Masouris, Ilias; Farina, Fabrizio; Pagliarulo, Caterina; Mantova, Giuseppe; Paragliola, Laura; Leib, Stephen; Koedel, Uwe; Pozzi, Gianni; Alifano, Pietro; Salvatore, Paola (2019). Virulence traits of serogroup C meningococcus and isogenic mutant, defective in surface-exposed sialic acid, in a murine model of meningitis. Infection and immunity, 87(4) American Society for Microbiology 10.1128/IAI.00688-18
Ott, Sebastian Robert; Meier, N; Kolditz, Martin; Bauer, Torsten T; Rohde, Gernot; Presterl, Elisabeth; Schürmann, Dirk; Lepper, Philipp M; Ringshausen, Felix C; Flick, Holger; Leib, Stephen; Pletz, Mathias W (2019). "Pulmonary Nocardiosis in Western Europe-Clinical evaluation of 43 patients and population-based estimates of hospitalization rates". International journal of infectious diseases, 81, pp. 140-148. Elsevier 10.1016/j.ijid.2018.12.010
Needle, David B; Selig, Martin K; Jackson, Kenneth A; Delwart, Eric; Tighe, Ellyn; Leib, Stephen L.; Seuberlich, Torsten; Pesavento, Patricia A (2019). Fatal bronchopneumonia caused by skunk adenovirus 1 in an African pygmy hedgehog. Journal of veterinary diagnostic investigation, 31(1), pp. 103-106. American Association of Veterinary Laboratory Diagnosticians AAVLD 10.1177/1040638718812123
Erni, Silvia T.; Fernandes, Gabriella; Buri, Michelle; Perny, Michael; Rutten, Rolf Jan; van Noort, Johannes M; Senn, Pascal; Grandgirard, Denis; Roccio, Marta; Leib, Stephen (2019). Anti-inflammatory and Oto-Protective Effect of the Small Heat Shock Protein Alpha B-Crystallin (HspB5) in Experimental Pneumococcal Meningitis. Frontiers in neurology, 10(570), p. 570. Frontiers Media S.A. 10.3389/fneur.2019.00570
Egli, Adrian; Blanc, Dominique S; Greub, Gilbert; Keller, Peter Michael; Lazarevic, Vladimir; Lebrand, Aitana; Leib, Stephen; Neher, Richard A; Perreten, Vincent; Ramette, Alban; Schrenzel, Jacques; Stephan, Roger; Wagner, Karolin; Wuethrich, Daniel; Xenarios, Ioannis (2018). Improving the quality and workflow of bacterial genome sequencing and analysis: paving the way for a Switzerland-wide molecular epidemiological surveillance platform. Swiss medical weekly, 148(w14693), w14693. EMH Media 10.4414/smw.2018.14693
van der Hoek, Lia; Verschoor, Ernst; Beer, Martin; Höper, Dirk; Wernike, Kerstin; Van Ranst, Marc; Matthijnssens, Jelle; Maes, Piet; Sastre, Patricia; Rueda, Paloma; Drexler, Jan Felix; Barr, John; Edwards, Thomas; Millner, Paul; Vermeij, Paul; de Groof, Ad; Thiel, Volker; Dijkman, Ronald; Suter, Franziska Marta; Leib, Stephen; ... (2018). Host switching pathogens, infectious outbreaks and zoonosis: A Marie Skłodowska-Curie innovative training network (HONOURs). Virus research, 257, pp. 120-124. Elsevier 10.1016/j.virusres.2018.09.002
Muri, Lukas; Grandgirard, Denis; Buri, Michelle; Perny, Michael; Leib, Stephen (2018). Combined effect of non-bacteriolytic antibiotic and inhibition of matrix metalloproteinases prevents brain injury and preserves learning, memory and hearing function in experimental paediatric pneumococcal meningitis. Journal of neuroinflammation, 15(1), p. 233. BioMed Central 10.1186/s12974-018-1272-8
Nasher, Fauzy; Förster, Sunniva; Yildirim, Efe C; Grandgirard, Denis; Leib, Stephen; Heller, Manfred; Hathaway, Lucy (2018). Foreign peptide triggers boost in pneumococcal metabolism and growth. BMC microbiology, 18(1), p. 23. BioMed Central 10.1186/s12866-018-1167-y
Glas, Michael; Frick, Tamara; Springe, Dirk; Putzu, Alessandro; Zürcher, Patrick; Grandgirard, Denis; Leib, Stephen; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2018). Neuroprotection with the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model. Shock, 49(2), pp. 229-234. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000917
Bewersdorf, Jan P; Grandgirard, Denis; Koedel, Uwe; Leib, Stephen (2018). Novel and preclinical treatment strategies in pneumococcal meningitis. Current opinion in infectious diseases, 31(1), pp. 85-92. Lippincott Williams & Wilkins 10.1097/QCO.0000000000000416
Ruppen, Corinne; Mercier, Thomas; Grandgirard, Denis; Leib, Stephen; El Haj, Cristina; Murillo, Oscar; Decosterd, Laurent; Sendi, Parham (2018). Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An Study With an Experimental Model of Foreign-Body Infection. Frontiers in Microbiology, 9, p. 919. Frontiers 10.3389/fmicb.2018.00919
Lenz, Nicole; Engler, Olivier; Grandgirard, Denis; Leib, Stephen L.; Ackermann-Gäumann, Rahel (2018). Evaluation of antivirals against tick-borne encephalitis virus in organotypic brain slices of rat cerebellum. PLoS ONE, 13(10), e0205294. Public Library of Science 10.1371/journal.pone.0205294
Grüter, B; Nevzati, E; Täschler, D; Strange, F; Rey, J; Grandgirard, D.; Leib, Stephen; von Gunten, M; Widmer, Hans Rudolf; Remonda, L; Fandino, J; Coluccia, D; Marbacher, S (2018). Neointima formation and thrombus organization after coil and stent treatments is mediated by cell migration from the adjacent vital vessel wall in rat sidewall aneurysms. Journal of neurological surgery. Part A, Central European neurosurgery, 79(S1), S1-S27. Thieme 10.1055/s-0038-1660695
Grüter, B; Strange, F; Täschler, D; Rey, J; von Gunten, M; Grandgirard, D.; Leib, Stephen; Remonda, L; Widmer, Hans Rudolf; Nevzati, E; Fandino, J; Marbacher, S; Coluccia, D (2018). A biodegradable magnesium stent for aneurysm healing in a rat sidewall aneurysm model. Journal of neurological surgery. Part A, Central European neurosurgery, 79(S 01), S1-S27. Thieme 10.1055/s-0038-1660694
Oechslin, Corinne Pia; Lenz, Nicole; Liechti, Nicole; Ryter, Sarah; Agyeman, Philipp; Bruggmann, Rémy; Leib, Stephen; Beuret, Christian M (2018). Limited Correlation of Shotgun Metagenomics Following Host Depletion and Routine Diagnostics for Viruses and Bacteria in Low Concentrated Surrogate and Clinical Samples. Frontiers in cellular and infection microbiology, 8(375), p. 375. Frontiers 10.3389/fcimb.2018.00375
Perny, Michael; Solyga, Magdalena; Grandgirard, Denis; Roccio, Marta; Leib, Stephen; Senn, Pascal (2017). Streptococcus pneumoniae-induced ototoxicity in organ of Corti explant cultures. Hearing research, 350, pp. 100-109. Elsevier 10.1016/j.heares.2017.04.012
Jenkinson, Stephen P.; Grandgirard, Denis; Heidemann, Martina; Tscherter, Anne; Avondet, Marc-André; Leib, Stephen (2017). Embryonic Stem Cell-Derived Neurons Grown on Multi-Electrode Arrays as a Novel In vitro Bioassay for the Detection of Clostridium botulinum Neurotoxins. Frontiers in Pharmacology, 8(73) Frontiers 10.3389/fphar.2017.00073
Oechslin, Corinne P.; Heutschi, Daniel; Lenz, Nicole; Tischhauser, Werner; Péter, Olivier; Rais, Olivier; Beuret, Christian M.; Leib, Stephen; Bankoul, Sergei; Ackermann-Gäumann, Rahel (2017). Prevalence of tick-borne pathogens in questing Ixodes ricinus ticks in urban and suburban areas of Switzerland. Parasites & Vectors, 10(1), p. 558. BioMed Central 10.1186/s13071-017-2500-2
Alexanian, Michael; Maric, Daniel; Jenkinson, Stephen Philip; Mina, Marco; Friedman, Clayton E.; Ting, Ching-Chia; Micheletti, Rudi; Plaisance, Isabelle; Nemir, Mohamed; Maison, Damien; Kernen, Jasmin; Pezzuto, Iole; Villeneuve, Dominic; Burdet, Frédéric; Ibberson, Mark; Leib, Stephen; Palpant, Nathan J.; Hernandez, Nouria; Ounzain, Samir and Pedrazzini, Thierry (2017). A transcribed enhancer dictates mesendoderm specification in pluripotency. Nature communications, 8(1), p. 1806. Nature Publishing Group 10.1038/s41467-017-01804-w
Agyeman, Philipp; Grandgirard, Denis; Leib, Stephen (2017). Neuroinflammation in Bacterial Meningitis. In: Lyck, R; Enzmann, G (eds.) The Blood Brain Barrier and Inflammation. Progress in Inflammation Research (pp. 213-252). Springer Nature 10.1007/978-3-319-45514-3_10
Coutinho, Leonam G.; de Oliveira, Ana Helena Sales; Witwer, Matthias; Leib, Stephen; Agnez-Lima, Lucymara F. (2017). DNA repair protein APE1 is involved in host response during pneumococcal meningitis and its expression can be modulated by vitamin B6. Journal of neuroinflammation, 14(1), p. 243. BioMed Central 10.1186/s12974-017-1020-5
Koller, Roger; Barbani, Maria Teresa; Lüthi, Alexander; Zürcher, Samuel; Steinlin, Jacqueline; Leib, Stephen; Gorgievski, Meri (September 2016). Comparison of respiratory and Meningitis/Encephalitis viruses detected by FilmArray® multiplex PCR versus real-time PCR. Journal of clinical virology, 82, S39. Elsevier 10.1016/j.jcv.2016.08.076
Perny, Michael; Roccio, Marta; Grandgirard, Denis; Solyga, Magdalena; Senn, Pascal; Leib, Stephen (2016). The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis. Journal of neuroscience, 36(29), pp. 7740-7749. Society for Neuroscience 10.1523/JNEUROSCI.0554-16.2016
Curiao, Tânia; Marchi, Emmanuela; Grandgirard, Denis; León-Sampedro, Ricardo; Viti, Carlo; Leib, Stephen; Baquero, Fernando; Oggioni, Marco R; Martinez, José Luis; Coque, Teresa M (2016). Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure. BMC Genomics, 17(491), p. 491. BioMed Central 10.1186/s12864-016-2778-z
van de Beek, D; Cabellos, C; Dzupova, O; Esposito, S; Klein, M; Kloek, A T; Leib, Stephen; Mourvillier, B; Ostergaard, C; Pagliano, P; Pfister, H W; Read, R C; Sipahi, O Resat; Brouwer, M C (2016). ESCMID guideline: diagnosis and treatment of acute bacterial meningitis. Clinical microbiology and infection, 22(Suppl 3), S37-S62. Blackwell Publishing 10.1016/j.cmi.2016.01.007
Cag, Y; Erdem, H; Leib, Stephen; Defres, S; Kaya, S; Larsen, L; Poljak, M; Ozturk-Engin, D; Barsic, B; Argemi, X; Sørensen, S M; Bohr, A L; Tattevin, P; Gunst, J D; Baštáková, L; Jereb, M; Johansen, I S; Karabay, O; Pekok, A U; Sipahi, O R; ... (2016). Managing atypical and typical herpetic central nervous system infections: results of a multinational study. Clinical microbiology and infection, 22(6), 568.e9-568.e17. Blackwell Publishing 10.1016/j.cmi.2016.03.027
Fernández-López, David; Faustino, Joel; Klibanov, Alexander L; Derugin, Nikita; Blanchard, Elodie; Simon, Franziska; Leib, Stephen; Vexler, Zinaida S (2016). Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke. Journal of neuroscience, 36(10), pp. 2881-2893. Society for Neuroscience 10.1523/JNEUROSCI.0140-15.2016
Bürki, Sarah Elisabeth; Grandgirard, Denis; Datta, Alexandre N; Hackenberg, Annette; Martin, Florence; Schmitt-Mechelke, Thomas; Leib, Stephen L; Steinlin, Maja (2016). Inflammatory markers in pediatric stroke: An attempt to better understanding the pathophysiology. European journal of paediatric neurology, 20(2), pp. 252-260. Elsevier 10.1016/j.ejpn.2015.12.006
Bally, Lia; Grandgirard, Denis; Leib, Stephen (2016). Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis. Antimicrobial agents and chemotherapy, 60(3), pp. 1841-1846. American Society for Microbiology 10.1128/AAC.02429-15
Hathaway, Lucy Jane; Grandgirard, Denis; Valente, Luca Gabriele; Täuber, Martin G.; Leib, Stephen (2016). Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis. Open Biology, 6(3) The Royal Society Publishing 10.1098/rsob.150269
Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8
Baumgartner, Denja; Aebi, Susanne; Grandgirard, Denis; Leib, Stephen; Draeger, Annette; Babiychuk, Eduard; Hathaway, Lucy Jane (2016). Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes. BMC microbiology, 16(1), p. 154. BioMed Central 10.1186/s12866-016-0777-5
Medaglini, Donata; Harandi, Ali M; Ottenhoff, Tom H M; Siegrist, Claire-Anne; VSV-Ebovac Consortium, ; Leib, Stephen (2015). Ebola vaccine R&D: Filling the knowledge gaps. Science translational medicine, 7(317), 317ps24. American Association for the Advancement of Science 10.1126/scitranslmed.aad3106
Pires, João; Siriwardena, Thissa N.; Stach, Michaela; Tinguely, Regula; Kasraian Fard, Sara; Luzzaro, Francesco; Leib, Stephen; Darbre, Tamis; Reymond, Jean-Louis; Endimiani, Andrea (2015). In Vitro Activity of the Novel Antimicrobial Peptide Dendrimer G3KL against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 59(12), pp. 7915-7918. American Society for Microbiology 10.1128/AAC.01853-15
Frick, Tamara; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Hänggi, Matthias (2015). An improved simple rat model for global cerebral ischaemia by induced cardiac arrest. Neurological research, 38(4), pp. 373-380. Maney 10.1179/1743132815Y.0000000090
Liechti, Fabian D; Grandgirard, Denis; Leib, Stephen (2015). Bacterial meningitis: insights into pathogenesis and evaluation of new treatment options: a perspective from experimental studies. Future microbiology, 10(7), pp. 1195-1213. Future Medicine 10.2217/fmb.15.43
Liechti, F D; Grandgirard, Denis; Leib, Stephen (2015). The antidepressant fluoxetine protects the hippocampus from brain damage in experimental pneumococcal meningitis. Neuroscience, 297, pp. 89-94. Elsevier 10.1016/j.neuroscience.2015.03.056
Osthoff, Michael; Egli, Adrian; Schürch, Nadia; Leib, Stephen; Mihatsch, Felix; Frei, Reno (2015). Ein nicht alltägliches türkisches Souvenir. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 15(25), pp. 611-613. EMH Editores Medicorum Helveticorum
Grandgirard, Denis; Furi, Leonardo; Ciusa, Maria Laura; Baldassarri, Lucilla; Knight, Daniel R; Morrissey, Ian; Largiadèr, Carlo Rodolfo; Leib, Stephen; Oggioni, Marco R (2015). Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression. BMC Genomics, 16(345), p. 345. BioMed Central 10.1186/s12864-015-1544-y
Wang, Junhua; Vuitton, Dominique A; Müller, Norbert; Hemphill, Andrew; Spiliotis, Markus; Blagosklonov, Oleg; Grandgirard, Denis; Leib, Stephen; Shalev, Itay; Levy, Gary; Lu, Xiaomei; Lin, Renyong; Wen, Hao; Gottstein, Bruno (2015). Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice. PLoS neglected tropical diseases, 9(5), e0003755. Public Library of Science 10.1371/journal.pntd.0003755
Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC anesthesiology, 15(2), p. 2. BioMed Central 10.1186/1471-2253-15-2
Liechti, Fabian D; Bächtold, Fabian; Grandgirard, Denis; Leppert, David; Leib, Stephen (2015). The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis. Journal of neuroinflammation, 12(43), p. 43. BioMed Central 10.1186/s12974-015-0257-0
Fontes, Fabrícia Lima; de Araújo, Luíza Ferreira; Coutinho, Leonam Gomes; Leib, Stephen; Agnez-Lima, Lucymara Fassarella (2015). Genetic polymorphisms associated with the inflammatory response in bacterial meningitis. BMC medical genetics, 16(70), p. 70. BioMed Central 10.1186/s12881-015-0218-6
Oggioni, Marco R; Coelho, Joana Rosado; Furi, Leonardo; Knight, Daniel R; Viti, Carlo; Orefici, Graziella; Martinez, Jose-Luis; Freitas, Ana Teresa; Coque, Teresa M; Morrissey, Ian; BIOHYPO consortium, ; Leib, Stephen (2015). Significant Differences Characterise the Correlation Coefficients between Biocide and Antibiotic Susceptibility Profiles in Staphylococcus aureus. Current pharmaceutical design, 21(16), pp. 2054-2057. Bentham Science Publishers 10.2174/1381612821666150310103238
Ricci, Susanna; Grandgirard, Denis; Wenzel, Michael; Braccini, Tiziana; Salvatore, Paola; Oggioni, Marco R; Leib, Stephen; Koedel, Uwe (2014). Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis. BMC infectious diseases, 14(726), p. 726. BioMed Central 10.1186/s12879-014-0726-6
Maffioli, Carola; Grandgirard, Denis; Engler, Olivier; Leib, Stephen (2014). A tick-borne encephalitis model in infant rats infected with langat virus. Journal of neuropathology and experimental neurology, 73(12), pp. 1107-1115. Lippincott Williams & Wilkins 10.1097/NEN.0000000000000131
Coutinho, Leonam G; Christen, Stephan; Bellac, Caroline L; Fontes, Fabrícia; de Souza, Fladjule; Grandgirard, Denis; Leib, Stephen; Agnez-Lima, Lucymara F (2014). The kynurenine pathway is involved in bacterial meningitis. Journal of neuroinflammation, 11(169), p. 169. BioMed Central 10.1186/s12974-014-0169-4
Agyeman, Philipp; Grandgirard, Denis; Leib, Stephen (2014). Pathogenesis and Pathophysiology of Bacterial Infections. In: Scheld, Michael; Whitley, Richard J.; Marra, Christina M. (eds.) Infections of the Central Nervous System (pp. 341-364). Philadelphia, PA, USA: Lippincott Williams & Wilkins
Liechti, Fabian D; Grandgirard, Denis; Leppert, David; Leib, Stephen (2014). Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis. Infection and immunity, 82(4), pp. 1710-1718. American Society for Microbiology 10.1128/IAI.00073-14
Hirt-Minkowski, Patricia; Marti, Hans-Peter; Hönger, Gideon; Grandgirard, Denis; Leib, Stephen; Amico, Patrizia; Schaub, Stefan (2014). Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation. Transplant immunology, 30(1), pp. 1-6. Elsevier 10.1016/j.trim.2013.11.004
Holler, Jon G.; Brandt, Christian T.; Leib, Stephen L.; Rowland, Ian J.; Ostergaard, Christian (2014). Increase in hippocampal water diffusion and volume during experimental pneumococcal meningitis is aggravated by bacteremia. BMC infectious diseases, 14(1), p. 240. BioMed Central 10.1186/1471-2334-14-240
Liechti, Fabian D; Stüdle, Nicolas; Theurillat, Regula; Grandgirard, Denis; Thormann, Wolfgang; Leib, Stephen (2014). The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis. PLoS ONE, 9(11), e113607. Public Library of Science 10.1371/journal.pone.0113607
Baranger, Kévin; Rivera, Santiago; Liechti, Fabian D; Grandgirard, Denis; Bigas, Judit; Seco, Jesús; Tarrago, Teresa; Leib, Stephen; Khrestchatisky, Michel (2014). Endogenous and synthetic MMP inhibitors in CNS physiopathology. In: Dityatev, Alexander; Wehrle-Haller, Bernhard; Pitkänen, Asla (eds.) Brain Extracellular Matrix in Health and Disease. Progress in Brain Research: Vol. 214 (pp. 313-351). Elsevier 10.1016/B978-0-444-63486-3.00014-1
Peltola, Heikki; Leib, Stephen L. (2013). Performance of adjunctive therapy in bacterial meningitis depends on circumstances. Pediatric infectious disease journal, 32(12), pp. 1381-1382. Lippincott Williams & Wilkins 10.1097/INF.0000000000000066
Coutinho, Leonam G; Grandgirard, Denis; Leib, Stephen L.; Agnez-Lima, Lucymara F (2013). Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis. BMC infectious diseases, 13(1), p. 326. BioMed Central 10.1186/1471-2334-13-326
Jansen, Sandra; Podschun, Rainer; Leib, Stephen L.; Grötzinger, Joachim; Oestern, Stefanie; Michalek, Matthias; Pufe, Thomas; Brandenburg, Lars-Ove (2013). Expression and function of psoriasin (S100A7) and koebnerisin (S100A15) in the brain. Infection and immunity, 81(5), pp. 1788-1797. American Society for Microbiology 10.1128/IAI.01265-12
Comim, Clarissa M; Barichello, Tatiana; Grandgirard, Denis; Dal-Pizzol, Felipe; Quevedo, João; Leib, Stephen L. (2013). Caspase-3 mediates in part hippocampal apoptosis in sepsis. Molecular neurobiology, 47(1), pp. 394-398. Clifton, N.J.: Humana Press 10.1007/s12035-012-8354-x
Monney, Thierry; Grandgirard, Denis; Leib, Stephen; Hemphill, Andrew (2013). Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model. Pathogens, 2(2), pp. 193-208. MDPI AG 10.3390/pathogens2020193
Zysset-Burri, Denise C.; Bellac, Caroline L; Leib, Stephen L.; Wittwer, Matthias (2013). Vitamin B6 reduces hippocampal apoptosis in experimental pneumococcal meningitis. BMC infectious diseases, 13, p. 393. BioMed Central 10.1186/1471-2334-13-393
Grandgirard, Denis; Gäumann, Rahel; Coulibaly, Boubacar; Dangy, Jean-Pierre; Sie, Ali; Junghanss, Thomas; Schudel, Hans; Pluschke, Gerd; Leib, Stephen L. (2013). The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis. Mediators of inflammation, 2013, p. 312476. Hindawi Publishing Corp. 10.1155/2013/312476
Jegerlehner, Sabrina; Vogel, Daniel; Tappeiner, Christoph; Leib, Stephen (2012). What vision loss might bring to light. Praxis - schweizerische Rundschau für Medizin, 101(6), pp. 419-423. Bern: Huber 10.1024/1661-8157/a000869
Mitchell, Andrew J.; Yau, Belinda; McQuillan, James A; Ball, Helen J.; Too, Lay Khoon; Abtin, Arby; Hertzog, Paul; Leib, Stephen L.; Jones, Cheryl A.; Gerega, Sebastien K.; Weninger, Wolfgang; Hunt, Nicholas H. (2012). Inflammasome-dependent IFN-γ drives pathogenesis in Streptococcus pneumoniae meningitis. Journal of immunology, 189(10), pp. 4970-80. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1201687
Maffioli, Carola; Grandgirard, Denis; Engler, Olivier; Leib, Stephen L. (2012). SiRNA inhibits replication of Langat virus, a member of the tick-borne encephalitis virus complex in organotypic rat brain slices. PLoS ONE, 7(9), e44703. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0044703
Monney, Thierry; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew (2012). Vaccination with the recombinant chimeric antigen recNcMIC3-1-R induces a non-protective Th2-type immune response in the pregnant mouse model for N. caninum infection. Vaccine, 30(46), pp. 6588-94. Amsterdam: Elsevier 10.1016/j.vaccine.2012.08.024
Guldimann, Claudia; Lejeune, Beatrice; Hofer, Sandra; Leib, Stephen L.; Frey, Joachim; Zurbriggen, Andreas; Seuberlich, Torsten; Oevermann, Anna (2012). Ruminant organotypic brain-slice cultures as a model for the investigation of CNS listeriosis. International journal of experimental pathology, 93(4), pp. 259-268. Oxford: Blackwell Science 10.1111/j.1365-2613.2012.00821.x
Grandgirard, Denis; Burri, Melchior; Agyeman, Philipp; Leib, Stephen (2012). Adjunctive daptomycin attenuates brain damage and hearing loss more efficiently than rifampin in infant rat pneumococcal meningitis. Antimicrobial agents and chemotherapy, 56(8), pp. 4289-95. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00674-12
Hofer, Sandra; Magloire, Vincent; Streit, Jürg; Leib, Stephen L. (2012). Grafted neuronal precursor cells differentiate and integrate in injured hippocampus in experimental pneumococcal meningitis. Stem cells, 30(6), pp. 1206-15. Durham: AlphaMed Press
Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007
Zimmermann, J; Mina, A; Hofer, S; Di Santo, S; Grandgirard, D; Widmer, HR; Senn, P; Leib, Stephen (2011). Grafting of neuronal precursor cells in auditory spiral ganglion loss after experimental bacterial meningitis. In: Clinical Neuroscience Meeting. Bern: Clinical Neuroscience Meeting
Woehrl, Bianca; Klein, Matthias; Grandgirard, Denis; Koedel, Uwe; Leib, Stephen (2011). Bacterial meningitis: current therapy and possible future treatment options. Expert review of anti-infective therapy, 9(11), pp. 1053-1065. London: Expert Reviews 10.1586/ERI.11.129
Hofer, Sandra; Grandgirard, Denis; Burri, Denise; Fröhlich, Tanja K.; Leib, Stephen L. (2011). Bacterial meningitis impairs hippocampal neurogenesis. Journal of neuropathology and experimental neurology, 70(10), pp. 890-899. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e3182303f31
Monney, Thierry; Rütti, David; Schorer, Michelle; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew (2011). RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection. Vaccine, 29(40), pp. 6967-6975. Amsterdam: Elsevier 10.1016/j.vaccine.2011.07.038
da Silva, Thayse Azevedo; Fontes, Fabrícia Lima; Coutinho, Leonam Gomes; de Souza, Fladjule Rejane Soares; de Melo, Julliane Tamara Araújo; de Souto, Janeusa Trindade; Leib, Stephen L.; Agnez-Lima, Lucymara Fassarella (2011). SNPs in DNA repair genes associated to meningitis and host immune response. Mutation research - fundamental and molecular mechanisms of mutagenesis, 713(1-2), pp. 39-47. Amsterdam: Elsevier 10.1016/j.mrfmmm.2011.05.012
de Souza, Fladjule Rejane Soares; Fontes, Fabrícia Lima; da Silva, Thayse Azevedo; Coutinho, Leonam Gomes; Leib, Stephen L.; Agnez-Lima, Lucymara Fassarella (2011). Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis. BMC medical genetics, 12(51), p. 51. London: BioMed Central 10.1186/1471-2350-12-51
Blaser, Cornelia; Wittwer, Matthias; Grandgirard, Denis; Leib, Stephen L. (2011). Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis. PLoS ONE, 6(3), e17840. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0017840
Braun, Benedikt J.; Slowik, Alexander; Leib, Stephen L.; Lucius, Ralph; Varoga, Deike; Wruck, Christoph J.; Jansen, Sandra; Podschun, Rainer; Pufe, Thomas; Brandenburg, Lars-Ove (2011). The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis. Journal of neuroinflammation, 8(1), p. 11. London: BioMed Central 10.1186/1742-2094-8-11
Margos, M.C.; Grandgirard, Denis; Leib, Stephen; Gottstein, Bruno (2011). In vitro induction of lymph node cell proliferation by mouse bone marrow dendritic cells following stimulation with different Echinococcus multilocularis antigens. Journal of helminthology, 85(2), pp. 128-137. Cambridge: Cambridge University Press 10.1017/S0022149X10000878
Gottstein, Bruno; Wittwer, Matthias; Schild, Marc; Merli, Michael; Leib, Stephen L.; Müller, Norbert; Müller, Joachim; Jaggi, Rolf (2010). Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggs. PLoS ONE, 5(4), e9779. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0009779
Bellac, Caroline L.; Coimbra, Roney S.; Christen, Stephan; Leib, Stephen L. (2010). Inhibition of the kynurenine-NAD+ pathway leads to energy failure and exacerbates apoptosis in pneumococcal meningitis. Journal of neuropathology and experimental neurology, 69(11), pp. 1096-1104. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e3181f7e7e9
Grandgirard, Denis; Leib, Stephen L. (2010). Meningitis in neonates: bench to bedside. Clinics in perinatology, 37(3), pp. 655-676. New York, N.Y.: Elsevier 10.1016/j.clp.2010.05.004
Wittwer, Matthias; Grandgirard, Denis; Rohrbach, Janine; Leib, Stephen L. (2010). Tracking the transcriptional host response from the acute to the regenerative phase of experimental pneumococcal meningitis. BMC infectious diseases, 10(176), p. 176. London: BioMed Central 10.1186/1471-2334-10-176
Blaser, Cornelia; Klein, Matthias; Grandgirard, Denis; Wittwer, Matthias; Peltola, Heikki; Weigand, Michael; Koedel, Uwe; Leib, Stephen L. (2010). Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis. BMC infectious diseases, 10(84), p. 84. London: BioMed Central 10.1186/1471-2334-10-84
Sellner, Johann; Täuber, Martin G.; Leib, Stephen L. (2010). Pathogenesis and pathophysiology of bacterial CNS infections. Handbook of clinical neurology, 96, pp. 1-16. Amsterdam: Elsevier 10.1016/S0072-9752(09)96001-8
Grandgirard, Denis; Oberson, Kevin; Bühlmann, Angela; Gäumann, Rahel; Leib, Stephen L. (2010). Attenuation of cerebrospinal fluid inflammation by the nonbacteriolytic antibiotic daptomycin versus that by ceftriaxone in experimental pneumococcal meningitis. Antimicrobial agents and chemotherapy, 54(3), pp. 1323-1326. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00812-09
Østergaard, Christian; Leib, Stephen L.; Rowland, Ian; Brandt, Christian T. (2010). Bacteremia causes hippocampal apoptosis in experimental pneumococcal meningitis. BMC infectious diseases, 10(1), p. 1. London: BioMed Central 10.1186/1471-2334-10-1
Klein, M; Pfister, H W; Leib, Stephen L.; Koedel, U (2009). Therapy of community-acquired acute bacterial meningitis: the clock is running. Expert opinion on pharmacotherapy, 10(16), pp. 2609-2623. Informa Healthcare 10.1517/14656560903277210
Sellner, Johann; Buonomano, Roberto; Nedeltchev, Krassen; Findling, Oliver; Schroth, Gerhard; Surbek, Daniel; Leib, Stephen L. (2009). A case of maternal herpes simplex virus encephalitis during late pregnancy. Nature clinical practice - neurology, 5(1), pp. 51-56. New York, N.Y.: Nature Publishing Group 10.1038/ncpneuro0972
Stickel, Felix; Droz, Sara; Patsenker, Eleonora; Bögli-Stuber, Katja; Aebi, Beat; Leib, Stephen L. (2009). Severe hepatotoxicity following ingestion of Herbalife nutritional supplements contaminated with Bacillus subtilis. Journal of hepatology, 50(1), pp. 111-117. Amsterdam: Elsevier 10.1016/j.jhep.2008.08.017
Brandenburg, Lars-Ove; Varoga, Deike; Nicolaeva, Nicoletta; Leib, Stephen L.; Podschun, Rainer; Wruck, Christoph J.; Wilms, Henrik; Lucius, Ralph; Pufe, Thomas (2009). Expression and regulation of antimicrobial peptide rCRAMP after bacterial infection in primary rat meningeal cells. Journal of neuroimmunology, 217(1-2), pp. 55-64. Amsterdam: Elsevier 10.1016/j.jneuroim.2009.10.004
Debache, Karim; Alaeddine, Ferial; Guionaud, Christophe; Monney, Thierry; Müller, Joachim; Strohbusch, Maria; Leib, Stephen L.; Grandgirard, Denis; Hemphill, Andrew (2009). Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally infected with Neospora caninum tachyzoites. International journal for parasitology, 39(12), pp. 1373-1384. Kidlington, UK: Elsevier 10.1016/j.ijpara.2009.04.006
Sellner, Johann; Grandgirard, Denis; Gianinazzi, Christian; Landmann, Regine M.; Leib, Stephen L. (2009). Effects of Toll-like receptor 2 agonist Pam(3)CysSK(4) on inflammation and brain damage in experimental pneumococcal meningitis. Journal of neuroimmunology, 206(1-2), pp. 28-31. Amsterdam: Elsevier 10.1016/j.jneuroim.2008.10.004
Strohbusch, M.; Muller, N.; Hemphill, A.; Margos, M.; Grandgirard, D.; Leib, Stephen; Greif, G.; Gottstein, B. (2009). Neospora caninum and bone marrow-derived dendritic cells: parasite survival, proliferation, and induction of cytokine expression. Parasite immunology, 31(7), pp. 366-372. Oxford: Blackwell Scientific Publications 10.1111/j.1365-3024.2009.01112.x
Horvath, Christina E.; Brinkmann, Christian K.; Ozdoba, Christoph; Leib, Stephen; Wolf, Sebastian; Wolf-Schnurrbusch, Ute E.K. (2009). Chorioretinal nocardiosis. Retinal Cases & Brief Reports, 3(3), pp. 263-265. Lippincott Williams & Wilkins 10.1097/ICB.0b013e31817376eb
Gehre, F.; Leib, Stephen L.; Grandgirard, Denis; Kummer, Jürg; Bühlmann, Angela; Simon, Franziska; Gäumann, R.; Kharat, A. S.; Täuber, Martin G.; Tomasz, A. (2008). Essential role of choline for pneumococcal virulence in an experimental model of meningitis. Internal medicine journal, 264(2), pp. 143-154. Sydney: Blackwell 10.1111/j.1365-2796.2008.01930.x
Sury, Matthias D.; Agarinis, Claudia; Widmer, Hans-Rudolf; Leib, Stephen L.; Christen, Stephan (2008). JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 32(1), pp. 142-150. Amsterdam: Elsevier 10.1016/J.nbd.2008.07.006
Sellner, Johann; Greeve, Isabell; Findling, Oliver; Kamm, Christian P.; Minten, Carsten; Engelhardt, Britta; Grandgirard, Denis; Leib, Stephen L.; Mattle, Heinrich P (2008). Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis. Neurochemistry international, 53(1-2), pp. 17-21. Amsterdam: Elsevier 10.1016/j.neuint.2008.04.004
Brandenburg, Lars-Ove; Varoga, Deike; Nicolaeva, Nicoletta; Leib, Stephen L.; Wilms, Henrik; Podschun, Rainer; Wruck, Christoph J; Schröder, Jens-Michael; Pufe, Thomas; Lucius, Ralph (2008). Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis. Journal of neuropathology and experimental neurology, 67(11), pp. 1041-1054. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e31818b4801
Grandgirard, Denis; Loeffler, Jutta M.; Fischetti, Vincent A.; Leib, Stephen L. (2008). Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis. Journal of infectious diseases, 197(11), pp. 1519-1522. Cary, N.C.: The University of Chicago Press 10.1086/587942
Sellner, Johann; Ringer, Ralph; Baumann, Pierre; Perey, Michèl Jonzier; Schmitt, Bernhard; Leib, Stephen L. (2008). Effect of the NMDA-receptor antagonist dextromethorphan in infant rat pneumococcal meningitis. Current drug metabolism, 9(1), pp. 83-88. Hilversum: Bentham Science Publishers
Sellner, Johann; Greeve, Isabell; Leib, Stephen L.; Mattle, Heinrich P. (2008). Atorvastatin does not alter interferon Beta-induced changes of serum matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 in patients with multiple sclerosis. Archives of neurology, 65(5), pp. 672-674. Chicago, Ill.: American Medical Association 10.1001/archneur.65.5.672
Sellner, Johann; Greeve, I; Findling, O; Grandgirard, Denis; Leib, Stephen L.; Mattle, H P (2008). Atorvastatin does not alter serum levels of sCD95 and sCD95L in multiple sclerosis. Clinical and experimental immunology, 152(2), pp. 280-284. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2008.03630.x
Ren, Hao; Leib, Stephen L.; Ferriero, Donna M; Täuber, Martin G.; Christen, Stephan (2007). Induction of haem oxygenase-1 causes cortical non-haem iron increase in experimental pneumococcal meningitis: evidence that concomitant ferritin up-regulation prevents iron-induced oxidative damage. Journal of neurochemistry, 100(2), pp. 532-544. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2006.04230.x
Grandgirard, Denis; Steiner, Oliver; Täuber, Martin G.; Leib, Stephen L. (2007). An infant mouse model of brain damage in pneumococcal meningitis. Acta neuropathologica, 114(6), pp. 609-617. Berlin: Springer-Verlag 10.1007/s00401-007-0304-8
Trampuz, Andrej; Steinhuber, Andrea; Wittwer, Matthias; Leib, Stephen L. (2007). Rapid diagnosis of experimental meningitis by bacterial heat production in cerebrospinal fluid. BMC infectious diseases, 7, p. 116. London: BioMed Central 10.1186/1471-2334-7-116
Bellac, Caroline L; Coimbra, Roney S; Simon, Franziska; Imboden, Johann; Leib, Stephen L. (2007). Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis. Neurobiology of disease, 28(2), pp. 175-183. Amsterdam: Elsevier 10.1016/j.nbd.2007.07.005
Coimbra, Roney S; Loquet, Gérard; Leib, Stephen L. (2007). Limited efficacy of adjuvant therapy with dexamethasone in preventing hearing loss due to experimental pneumococcal meningitis in the infant rat. Pediatric research, 62(3), pp. 291-294. New York, N.Y.: Nature Publishing Group 10.1203/PDR.0b013e318123fb7c
Zimmerli, Stefan; Knecht, Urspeter; Leib, Stephen L. (2007). A model of cerebral aspergillosis in non-immunosuppressed nursing rats. Acta neuropathologica, 114(4), pp. 411-418. Berlin: Springer-Verlag 10.1007/s00401-007-0255-0
Echchannaoui, Hakim; Leib, Stephen L.; Neumann, Ulf; Landmann, Regine M. A. (2007). Adjuvant TACE inhibitor treatment improves the outcome of TLR2-/- mice with experimental pneumococcal meningitis. BMC infectious diseases, 7(25), p. 25. London: BioMed Central 10.1186/1471-2334-7-25
Grandgirard, Denis; Schürch, Christian; Cottagnoud, Philippe; Leib, Stephen L. (2007). Prevention of brain injury by the nonbacteriolytic antibiotic daptomycin in experimental pneumococcal meningitis. Antimicrobial agents and chemotherapy, 51(6), pp. 2173-2178. Washington, D.C.: American Society for Microbiology 10.1128/AAC.01014-06
Grandgirard, D; Bifrare, Y-D; Pleasure, S J; Kummer, J; Leib, Stephen L.; Tauber, Martin G. (2007). Pneumococcal meningitis induces apoptosis in recently postmitotic immature neurons in the dentate gyrus of neonatal rats. Developmental neuroscience, 29(1-2), pp. 134-142. Basel: Karger 10.1159/000096218
Sellner, Johann; Leib, Stephen L. (2007). Flu-related neurological complications: incidence and risk factors in children. Nature clinical practice - neurology, 3(11), pp. 606-607. New York, N.Y.: Nature Publishing Group 10.1038/ncpneuro0610
Leib, Stephen L. (2007). An in vitro model of central nervous system infection and regeneration: neuronal stem cells as targets of brain damage and regenerative therapies in bacterial meningitis. ALTEX-Alternatives to Animal Experimentation, 24 Spec No, pp. 90-92. Springer
Rauch, A; Droz, S; Zimmerli, Stefan; Leib, Stephen L. (2006). Dysphagia in elderly women: consider tetanus. Infection, 34(1), pp. 35-38. Heidelberg: Urban & Vogel 10.1007/s15010-006-4151-7
Sellner, Johann; Simon, Franziska; Meyding-Lamade, Uta; Leib, Stephen L. (2006). Herpes-simplex virus encephalitis is characterized by an early MMP-9 increase and collagen type IV degradation. Brain research, 1125(1), pp. 155-162. Amsterdam: Elsevier 10.1016/j.brainres.2006.09.093
Sellner, Johann; Leib, Stephen L. (2006). In bacterial meningitis cortical brain damage is associated with changes in parenchymal MMP-9/TIMP-1 ratio and increased collagen type IV degradation. Neurobiology of disease, 21(3), pp. 647-656. Amsterdam: Elsevier 10.1016/j.nbd.2005.09.007
Bellac, Caroline L.; Coimbra, Roney S.; Christen, Stephan; Leib, Stephen L. (2006). Pneumococcal meningitis causes accumulation of neurotoxic kynurenine metabolites in brain regions prone to injury. Neurobiology of disease, 24(2), pp. 395-402. Amsterdam: Elsevier 10.1016/j.nbd.2006.07.014
Boscacci, Rémy; Leib, Stephen L. (2006). [Invasive meningococcal infections: two cases that demonstrate the broad spectrum in clinical manifestation and outcome]. Praxis - schweizerische Rundschau für Medizin, 95(43), pp. 1675-1678. Bern: Huber 10.1024/1661-8157.95.43.1675
Meli, Damian N.; Coimbra, Roney S.; Erhart, Dominik G.; Loquet, Gerard; Bellac, Caroline L.; Täuber, Martin G.; Neumann, Ulf; Leib, Stephen L. (2006). Doxycycline reduces mortality and injury to the brain and cochlea in experimental pneumococcal meningitis. Infection and immunity, 74(7), pp. 3890-3896. New York, N.Y.: American Society for Microbiology 10.1128/IAI.01949-05
Coimbra, Roney S.; Voisin, Veronique; de Saizieu, Antoine B.; Lindberg, Raija L. P.; Wittwer, Matthias; Leppert, David; Leib, Stephen L. (2006). Gene expression in cortex and hippocampus during acute pneumococcal meningitis. BMC biology, 4, p. 15. London: BioMed Central 10.1186/1741-7007-4-15
Grandgirard, Denis; Leib, Stephen L. (2006). Strategies to prevent neuronal damage in paediatric bacterial meningitis. Current opinion in pediatrics, 18(2), pp. 112-118. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/01.mop.0000193292.09894.b7
Lindberg, R L P; Sorsa, T; Tervahartiala, T; Hoffmann, F; Mellanen, L; Kappos, L; Schaad, U B; Leib, Stephen L.; Leppert, D (2006). Gelatinase B [matrix metalloproteinase (MMP)-9] and collagenases (MMP-8/-13) are upregulated in cerebrospinal fluid during aseptic and bacterial meningitis in children. Neuropathology & applied neurobiology, 32(3), pp. 304-317. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2990.2006.00729.x
Zucker, K E; Kamberi, P; Sobel, R A; Cloud, G; Meli, D N; Clemons, K V; Stevens, D A; Williams, P L; Leib, Stephen L. (2006). Temporal expression of inflammatory mediators in brain basilar artery vasculitis and cerebrospinal fluid of rabbits with coccidioidal meningitis. Clinical and experimental immunology, 143(3), pp. 458-466. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2006.03011.x
Gianinazzi, Christian; Schild, Marc; Müller, Nicole; Leib, Stephen; Simon, F; Nunez, Sandra; Joss, Philipp; Gottstein, Bruno (2005). Organotypic slice cultures from rat brain tissue: a new approach for Naegleria fowleri CNS infection in vitro. Parasitology, 131(6), pp. 797-804. Cambridge University Press 10.1017/S0031182005008619
Scheidegger, Alexandra; Vonlaufen, Nathalie Françoise F.; Naguleswaran, Arunasalam; Gianinazzi, Christian; Müller, Norbert; Leib, Stephen; Hemphill, Andrew (2005). Differential effects of interferon-gamma and tumor necrosis factor-alpha on Toxoplasma gondii proliferation in organotypic rat brain slice cultures. Journal of parasitology, 91(2), pp. 307-315. American Society of Parasitologists 10.1645/GE-379R
Bifrare, Yoeng-Delphine; Kummer, Jürg; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2005). Brain-derived neurotrophic factor protects against multiple forms of brain injury in bacterial meningitis. Journal of infectious diseases, 191(1), pp. 40-45. The University of Chicago Press 10.1086/426399
Meli, D. N.; Loeffler, J. M.; Baumann, P.; Neumann, U.; Buhl, T.; Leppert, D.; Leib, Stephen L (2004). In pneumococcal meningitis a novel water-soluble inhibitor of matrix metalloproteinases and TNF-alpha converting enzyme attenuates seizures and injury of the cerebral cortex. Journal of neuroimmunology, 151(1-2), pp. 6-11. Elsevier 10.1016/j.jneuroim.2004.01.026
Gianinazzi, Christian; Grandgirard, Denis; Simon, Franziska; Imboden, Hans; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2004). Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited. Journal of neuropathology and experimental neurology, 63(6), pp. 610-617. Lippincott Williams & Wilkins
Leib, Stephen L; Heimgartner, Chris; Bifrare, Yoeng-Delphine; Loeffler, Jutta M; Täuber, Martin G (2003). Dexamethasone aggravates hippocampal apoptosis and learning deficiency in pneumococcal meningitis in infant rats. Pediatric research, 54(3), pp. 353-357. Nature Publishing Group 10.1203/01.PDR.0000079185.67878.72
Schaper, Manuela; Leib, Stephen; Meli, Damian N; Brandes, Ralf P; Täuber, Martin G.; Christen, Stephan (2003). Differential effect of p47phox and gp91phox deficiency on the course of Pneumococcal Meningitis. Infection and immunity, 71(7), pp. 4087-4092. American Society for Microbiology 10.1128/IAI.71.7.4087-4092.2003
Ghielmetti, Marco; Ren, Hao; Leib, Stephen; Täuber, Martin G.; Christen, Stephan (2003). Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis. Brain research, 976(2), pp. 139-148. Elsevier 10.1016/S0006-8993(03)02557-5
Fux, C; Bodmer, Thomas; Ziswiler, Hans Rudolf; Leib, Stephen (2003). [Nocardia cyriacigeorgici: First report of invasive human infection]. Deutsche medizinische Wochenschrift, 128(19), pp. 1038-1041. Thieme 10.1055/s-2003-39102
Gianinazzi, Christian; Grandgirard, Denis; Imboden, Hans; Egger, Lotti; Meli, Damian N; Bifrare, Yoeng-Delphine; Joss, Philipp; Täuber, Martin G.; Borner, Christoph; Leib, Stephen (2003). Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta neuropathologica, 105(5), pp. 499-507. Springer 10.1007/s00401-003-0672-7
Coumans, Audrey B C; Middelanis, Johannes S; Garnier, Yves; Vaihinger, Hans-Martin; Leib, Stephen L; Von Duering, Monika U; Hasaart, Tom H M; Jensen, Arne; Berger, Richard (2003). Intracisternal application of endotoxin enhances the susceptibility to subsequent hypoxic-ischemic brain damage in neonatal rats. Pediatric research, 53(5), pp. 770-775. Nature Publishing Group 10.1203/01.PDR.0000059221.40073.82
Meli, Damian N.; Christen, Stephan; Leib, Stephen L. (2003). Matrix metalloproteinase-9 in pneumococcal meningitis: activation via an oxidative pathway. Journal of infectious diseases, 187(9), pp. 1411-1415. Cary, N.C.: The University of Chicago Press 10.1086/374644
Kolarova, Anna; Ringer, Ralph; Täuber, Martin G.; Leib, Stephen L. (2003). Blockade of NMDA receptor subtype NR2B prevents seizures but not apoptosis of dentate gyrus neurons in bacterial meningitis in infant rats. BMC neuroscience, 4(21), p. 21. London: BioMed Central 10.1186/1471-2202-4-21
Bifrare, Yoeng-Delphine; Gianinazzi, Christian; Imboden, Hans; Leib, Stephen L; Täuber, Martin G. (2003). Bacterial meningitis causes two distinct forms of cellular damage in the hippocampal dentate gyrus in infant rats. Hippocampus, 13(4), pp. 481-488. Wiley-Liss 10.1002/hipo.10142
Remer, Katharina A.; Pfister, Hedi; Fatzer, Rosmarie; Leib, Stephen L.; Jungi, Thomas W. (2002). The role of nitric oxide in Listeria encephalitis of ruminants and in rats intracisternally infected with Listeria monocytogenes. Berliner und Münchener tierärztliche Wochenschrift, 115(7-8), pp. 259-266. Schlütersche
Vonlaufen, Nathalie; Gianinazzi, Christian; Müller, Norbert; Simon, Franziska; Björkman, Camilla; Jungi, Thomas W.; Leib, Stephen L.; Hemphill, Andrew (2002). Infection of organotypic slice cultures from rat central nervous tissue with Neospora caninum: an alternative approach to study host-parasite interactions. International journal for parasitology, 32(5), pp. 533-542. Elsevier 10.1016/S0020-7519(01)00351-4
Müller, Norbert; Vonlaufen, Nathalie Françoise F.; Gianinazzi, Christian; Leib, Stephen L.; Hemphill, Andrew (2002). Application of real-time fluorescent PCR for quantitative assessment of Neospora caninum infections in organotypic slice cultures of rat central nervous system tissue. Journal of clinical microbiology, 40(1), pp. 252-255. American Society for Microbiology 10.1128/JCM.40.1.252-255.2002
Schaper, Manuela; Gergely, Suzanne; Lykkesfeldt, Jens; Zbären, Jakob; Leib, Stephen L.; Täuber, Martin G.; Christen, Stephan (2002). Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis. Journal of neuropathology and experimental neurology, 61(7), pp. 605-13. Hagerstown, Md.: Lippincott Williams & Wilkins
Meli, Damian N.; Christen, Stephan; Leib, Stephen L.; Täuber, Martin G. (2002). Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae. Current opinion in infectious diseases, 15(3), pp. 253-357. Hagerstown, Md.: Wolters Kluwer Lippincott Williams & Wilkins 10.1097/00001432-200206000-00007
Pfister, H.; Remer, K. A.; Brcic, Marija; Fatzer, R.; Christen, Stephan; Leib, Stephen L.; Jungi, Thomas W. (2002). Inducible nitric oxide synthase and nitrotyrosine in listeric encephalitis: a cross-species study in ruminants. Veterinary pathology, 39(2), pp. 190-199. Middleton, Wis.: American College of Veterinary Pathologists 10.1354/vp.39-2-190
Williams, Paul L; Leib, Stephen; Kamberi, Perparim; Leppert, David; Sobel, Raymond A; Bifrare, Yoeng-Delphine; Clemons, Karl V; Stevens, David A (2002). Levels of matrix metalloproteinase-9 within cerebrospinal fluid in a rabbit model of coccidioidal meningitis and vasculitis. Journal of infectious diseases, 186(11), pp. 1692-1695. The University of Chicago Press 10.1086/345365
Echchannaoui, Hakim; Frei, Karl; Schnell, Christian; Leib, Stephen L.; Zimmerli, Werner; Landmann, Regine (2002). Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation. Journal of infectious diseases, 186(6), pp. 798-806. The University of Chicago Press 10.1086/342845
Loeffler, Jutta M.; Bodmer, Thomas; Zimmerli, Werner; Leib, Stephen L. (2001). Nocardial brain abscess: observation of treatment strategies and outcome in Switzerland from 1992 to 1999. Infection, 29(6), pp. 337-341. Springer-Medizin-Verlag 10.1007/s15010-001-1147-1
Leppert, David; Lindberg, Raija L.P.; Kappos, Ludwig; Leib, Stephen L. (2001). Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis. Brain research reviews, 36(2-3), pp. 249-257. Elsevier 10.1016/S0165-0173(01)00101-1
Piso, R J; Leib, Stephen L. (2001). [What is your diagnosis? Basal meningitis and rhombencephalitis. Blood culture positive for Listeria monocytogenes]. Praxis - schweizerische Rundschau für Medizin, 90(19), pp. 823-824. Huber
Christen, Stephan; Schaper, Manuela; Lykkesfeldt, Jens; Siegenthaler, Corinne; Bifrare, Yoeng-Delphine; Banic, Staša; Leib, Stephen L.; Täuber, Martin G. (2001). Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment. Free radical biology & medicine, 31(6), pp. 754-762. San Diego, Calif.: Elsevier 10.1016/S0891-5849(01)00642-6
Christen, Stephan; Bifrare, Yeong-Delphine; Siegenthaler, Corinne; Leib, Stephen L.; Täuber, Martin G. (2001). Marked elevation in cortical urate and xanthine oxidoreductase activity in experimental bacterial meningitis. Brain research, 900(2), pp. 244-251. Amsterdam: Elsevier 10.1016/S0006-8993(01)02311-3
Leib, Stephen L.; Clements, John M.; Lindberg, Raija L. P.; Heimgartner, Chris; Loeffler, Jutta M.; Pfister, Luz-Andrea; Täuber, Martin G.; Leppert, David (2001). Inhibition of matrix metalloproteinases and tumour necrosis factor alpha converting enzyme as adjuvant therapy in pneumococcal meningitis. Brain, 124(9), pp. 1734-1742. Oxford: Oxford University Press 10.1093/brain/124.9.1734
Remer, K. A.; Jungi, Thomas W.; Fatzer, R.; Täuber, Martin G.; Leib, Stephen L. (2001). Nitric oxide is protective in listeric meningoencephalitis of rats. Infection and immunity, 69(6), pp. 4086-4093. New York, N.Y.: American Society for Microbiology 10.1128/IAI.69.6.4086-4093.2001
Loeffler, Jutta M.; Ringer, Ralph; Hablützel, Martin; Täuber, Martin G.; Leib, Stephen L. (2001). The free radical scavenger alpha-phenyl-tert-butyl nitrone aggravates hippocampal apoptosis and learning deficits in experimental pneumococcal meningitis. Journal of infectious diseases, 183(2), pp. 247-252. Cary, N.C.: The University of Chicago Press 10.1086/317921
Pfister, LA; Tureen, JH; Shaw, S; Christen, S; Ferriero, DM; Täuber, MG; Leib, Stephen L. (2000). Endothelin inhibition improves cerebral blood flow and is neuroprotective in pneumococcal meningitis. Annals of neurology, 47(3), pp. 329-335. Hoboken, N.J.: Wiley-Blackwell 10.1002/1531-8249(200003)47:3<329::AID-ANA8>3.3.CO;2-I
Leib, Stephen L.; Täuber, MG (2000). [In search of strategies for preventing brain damage as a sequela of bacterial meningitis]. Schweizerische medizinische Wochenschrift, 130(24), pp. 928-35. Basel: B. Schwabe & Co.
Auer, Marc; Pfister, Luz-Andrea; Leppert, David; Täuber, Martin G.; Leib, Stephen L. (2000). Effects of clinically used antioxidants in experimental pneumococcal meningitis. Journal of infectious diseases, 182(1), pp. 347-350. Cary, N.C.: The University of Chicago Press 10.1086/315658
Leib, Stephen L.; Leppert, David; Clements, John; Täuber, Martin G. (2000). Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis. Infection and immunity, 68(2), pp. 615-620. New York, N.Y.: American Society for Microbiology 10.1128/IAI.68.2.615-620.2000
Leppert, David; Leib, Stephen L.; Grygar, C.; Miller, K. M.; Schaad, U. B.; Holländer, G. A. (2000). Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae. Clinical infectious diseases, 31(1), pp. 80-84. The University of Chicago Press 10.1086/313922
Leib, Stephen L.; Zimmerli, Werner (2000). Reply. Clinical infectious diseases, 30(5), pp. 837-838. The University of Chicago Press 10.1086/313779
Leib, Stephen; Täuber, Martin G. (1999). [Meningitis (I)--differential diagnosis; aseptic and chronic meningitis]. Therapeutische Umschau, 56(11), pp. 631-639. Huber 10.1024/0040-5930.56.11.631
Leib, Stephen; Täuber, Martin G. (1999). Pathogenesis of bacterial meningitis. Infectious disease clinics of North America, 13(3), pp. 527-548. Elsevier 10.1016/S0891-5520(05)70093-3
Garzoni, C; Leib, Stephen; Zimmerli, W (1999). [Pneumococcal meningitis as a complication of maxillary sinusitis. Purulent conjunctivitis is linked to maxillary sinusitis]. Praxis - schweizerische Rundschau für Medizin, 88(11), pp. 491-495. Huber
Leib, Stephen L.; Täuber, Martin G. (1999). [Meningitis (II)--acute bacterial meningitis]. Therapeutische Umschau, 56(11), pp. 640-646. Bern: Huber 10.1024/0040-5930.56.11.640
Michelet, C; Leib, Stephen; Bentue-Ferrer, D; Täuber, Martin G. (1999). Comparative efficacies of antibiotics in a rat model of meningoencephalitis due to Listeria monocytogenes. Antimicrobial agents and chemotherapy, 43(7), pp. 1651-1656. Washington, D.C.: American Society for Microbiology
Leib, Stephen; Boscacci, R; Gratzl, O; Zimmerli, W (1999). Predictive value of cerebrospinal fluid (CSF) lactate level versus CSF/blood glucose ratio for the diagnosis of bacterial meningitis following neurosurgery. Clinical infectious diseases, 29(1), pp. 69-74. The University of Chicago Press 10.1086/520184
Leib, Stephen L.; Kim, Young S.; Black, Stephen M.; Tureen, Jay H.; Täuber, Martin G. (1998). Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. Journal of infectious diseases, 177(3), pp. 692-700. Cary, N.C.: Oxford University Press 10.1086/514226
Bogdan, I.; Leib, Stephen L.; Bergeron, M.; Chow, L.; Täuber, Martin G. (1997). Tumor necrosis factor-alpha contributes to apoptosis in hippocampal neurons during experimental group B streptococcal meningitis. Journal of infectious diseases, 176(3), pp. 693-697. Cary, N.C.: The University of Chicago Press 10.1086/514092
Leib, Stephen; Kim, Y S; Chow, L L; Sheldon, R A; Täuber, Martin G. (1996). Reactive oxygen intermediates contribute to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B streptococci. Journal of clinical investigation, 98(11), pp. 2632-2639. American Society for Clinical Investigation 10.1172/JCI119084
Leib, Stephen; Kim, Y S; Black, S M; Ferriero, D M; Täuber, Martin G. (1996). Detrimental effect of nitric oxide inhibition in experimental bacterial meningitis. Annals of neurology, 39(4), pp. 555-556. Wiley-Blackwell 10.1002/ana.410390422
Leib, Stephen; Kim, YS; Ferriero, DM; Täuber, Martin G. (1996). Neuroprotective effect of excitatory amino acid antagonist kynurenic acid in experimental bacterial meningitis. Journal of infectious diseases, 173(1), pp. 166-171. Cary, N.C.: Oxford University Press 10.1093/infdis/173.1.166
Leib, Stephen (1994). [A case from practice (300). Lambliasis; possibly 2-year-old chronic infection. Maculopapillary pruritic exanthema of the hairy scalp and the sternum; seborrheic dermatitis; skin reaction to lambliasis? Horseshoe kidney]. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis, 83(29-30), pp. 836-837.
Leib, Stephen (1994). [A case from practice (305). Recurrent erysipelas--tinea pedis et unginum--chronic venous insufficiency]. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis, 83(39), pp. 1089-1090.
Böni, J; Emmerich, B S; Leib, Stephen; Wiestler, O D; Schüpbach, J; Kleihues, P (1993). PCR identification of HIV-1 DNA sequences in brain tissue of patients with AIDS encephalopathy. Neurology, 43(9), pp. 1813-1817. Lippincott Williams & Wilkins
Schlienger, R. G.; Haefeli, W. E.; Bircher, A.; Leib, Stephen L.; Lüscher, T. F. (1993). [Drug-induced Stevens-Johnson syndrome in a patient with AIDS]. Schweizerische Rundschau fuer Medizin Praxis, 82(33), pp. 888-892.
Wiestler, O. D.; Leib, Stephen L.; Brüstle, O.; Spiegel, H.; Kleihues, P. (1992). Neuropathology and pathogenesis of HIV encephalopathies. Acta histochemica, 42(Suppl.), pp. 107-114. Elsevier
Brüstle, O.; Spiegel, H.; Leib, Stephen L.; Finn, T.; Stein, H.; Kleihues, P.; Wiestler, O. D. (1992). Distribution of human immunodeficiency virus (HIV) in the CNS of children with severe HIV encephalomyelopathy. Acta neuropathologica, 84(1), pp. 24-31. Springer 10.1007/BF00427211
Kleihues, P.; Leib, Stephen L.; Strittmatter, C.; Wiestler, O. D.; Lang, W. (1991). HIV encephalopathy: incidence, definition and pathogenesis. Results of a Swiss collaborative study. Acta pathologica japonica, 41(3), pp. 197-205.
