04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Biochemistry and Molecular Medicine

University of Bern (800)
- 04 Faculty of Medicine (800)
  - Pre-clinic Human Medicine (800)
    - Institute of Biochemistry and Molecular Medicine (800)

Group by: Date | Name | Item Type | Refereed | No Grouping

Jump to: No | Yes

Number of items at this level: 621.

No

Kaethner, Marc; Zumstein, Pascal; Preza, Matías; Grossenbacher, Philipp; Bartetzko, Anissa; Lochner, Martin; Schürch, Stefan; Regnault, Clement; Villalobos Ramirez, Daniel; Lundström Stadelmann, Britta (27 July 2024). Investigation of the threonine metabolism of Echinococcus multilocularis: the threonine dehydrogenase as a potential drug target in alveolar echinococcosis (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.07.27.605433

Bátora, Dániel; Fischer, Jérôme P.; Kaderli, Reto M.; Varga, Maté; Lochner, Martin; Gertsch, Jürg (25 February 2024). Silicon-rhodamine functionalized evocalcet probes (EvoSiR) potently and selectively label calcium sensing receptors (CaSR) in vitro, in vivo and ex vivo (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.02.22.581561

Ekundayo, Babatunde; Arullampalam, Prakash; Gerber, Christian E.; Hämmerli, Anne-Flore; Guichard, Sabrina; Boukenna, Mey; Ross, Daniela; Lochner, Martin; Rougier, Jean-Sébastien; Stahlberg, Henning; Abriel, Hugues; Ni, Dongchun (23 January 2024). Identification of a Binding Site for Small Molecule Inhibitors Targeting Human TRPM4 (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.01.22.576650

Selimi, Zoja; Rougier, Jean-Sébastien; Abriel, Hugues; Kucera, Jan P (2023). No evidence of functional interactions between cardiac sodium channels. Biophysical journal, 122(3 S1), 101a-102a. Elsevier 10.1016/j.bpj.2022.11.736

Hill, Emily; Huang, Xianglin; Del Popolo, Ivana; La Mache, Circe; Lochner, Martin; Ladds, Graham; Frenguelli, Bruno G.; Wall, Mark J. (2 December 2022). Species-dependent actions of the Goαb selective adenosine A1 receptor agonist BnOCPA (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2022.12.02.518704

Wall, Mark J.; Hill, Emily; Huckstepp, Robert; Barkan, Kerry; Deganutti, Giuseppe; Leuenberger, Michele; Preti, Barbara; Winfield, Ian; Carvalho, Sabrina; Suchankova, Anna; Wei, Haifeng; Safitri, Dewi; Huang, Xianglin; Imlach, Wendy; La Mache, Circe; Dean, Eve; Hume, Cherise; Hayward, Stephanie; Oliver, Jess; Zhao, Fei-Yue; ... (27 April 2022). Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2020.04.04.023945

Espinoza, Cristian; Fuenzalida, Barbara; Leiva, Andrea (2022). Epigenetic Changes as a Possible Mechanism Leading to Increased Fetal Cardiovascular Disease Risk in Pregnancies with Gestational Diabetes Mellitus and/or Maternal Hypercholesterolemia. Current vascular pharmacology, 20(4), p. 381. Bentham Science 10.2174/1570161120666220314090700

Abou-Hamdan, Abbas; Mahler, Roman; Grossenbacher, Philipp; Biner, Olivier; Sjöstrand, Dan; Lochner, Martin; Högbom, Martin; von Ballmoos, Christoph (23 December 2021). Functional design of bacterial superoxide:quinone oxidoreductase (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.12.23.473985

Gertsch, Jürg (2021). Travelogues from the Rainforest: Notes on Prof. Otto Sticher's 85th birthday. Planta medica, 87(14), pp. 1123-1127. Thieme 10.1055/a-1508-0613

Arullampalam, Prakash; Preti, Barbara; Ross-Kaschitza, Daniela; Lochner, Martin; Rougier, Jean-Sébastien; Abriel, Hugues (2 June 2021). Species-specific effects of cation channel TRPM4 small-molecule inhibitors (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.06.01.446517

Augustynek, Bartlomiej; Gyimesi, Gergely; Dernic, Jan; Sallinger, Matthias; Albano, Giuseppe; Klesse, Gabriel J.; Kandasamy, Palanivel; Grabmayr, Herwig; Frischauf, Irene; Fuster, Daniel G.; Peinelt, Christine; Hediger, Matthias A.; Bhardwaj, Rajesh (2021). Dissecting gating mechanisms of Orai calcium channel paralogs using constitutively active Orai mutants that mimic STIM1-gated state (In Press) (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.10.26.465861

Deganutti, Giuseppe; Barkan, Kerry; Preti, Barbara; Leuenberger, Michele; Wall, Mark; Frenguelli, Bruno G.; Lochner, Martin; Ladds, Graham; Reynolds, Christopher A. (22 October 2020). Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2020.10.22.350827

Zaugg, Jonas; Ziegler, Fabian; Nuoffer, Jean-Marc; Moser-Hässig, Ruedi; Albrecht, Christiane (2019). EFFICIENT LEUCINE TRANSPORT ACROSS THE PLACENTAL BARRIER DEPENDS ON PHYSIOLOGICAL, OPPOSITELY DIRECTED LEUCINE GRADIENTS. Placenta, 83, e113-e113. Elsevier

Kallol, Sampada; Briggs, Louise; Mistry, Hiten D.; Moser, Ruedi; Schneider, Henning; Albrecht, Christiane (2019). COMPARISON OF IN VITRO PRE-ECLAMPSIA (PE) CELL MODELS WITH PE PLACENTAL TISSUE. Placenta, 83, e104-e104. Elsevier

Zaugg, Jonas; Zurkinden, Line; Melhem, Hassan; Kalakaran, Thuvaraga; Albrecht, Christiane (2019). ANTIOXIDANT TREATMENT RESCUES THE HYPERGLYCEMIC AND HYPERLIPIDEMIC EFFECTS ON PLACENTAL IRON HOMEOSTASIS. Placenta, 83, e93-e93. Elsevier

Gertsch, Jürg (2018). Analytical and Pharmacological Challenges in Cannabis Research. Planta medica, 84(4), p. 213. Thieme 10.1055/s-0044-101051

Ramakrishnan, Srinivasan; Serricchio, Mauro; Striepen, Boris; Bütikofer, Peter (2013). Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans. Progress in lipid research, 52(4), pp. 488-512. Elsevier 10.1016/j.plipres.2013.06.003

Charles, Roch-Philippe; Silva, Jilian; Iezza, Gioia; Phillips, Wayne A; McMahon, Martin (2013). BRAF V600E and PIK3CA H1074R cooperate to promote progression of anaplastic thyroid carcinoma in the mouse. Endocrine abstracts, 32(S16.1) BioScientifica 10.1530/endoabs.32.s16.1

Lüscher, Benjamin; Messerli, Marianne; Surbek, Daniel; Sager, Ruth; Albrecht, Christiane; Hediger, Matthias; Baumann, Marc (2012). Placental glucose transporter (Glut)-1 expression in preeclampsia. Placenta, 33(9), A90-A90. Elsevier

Ilgü, Hüseyin; Turan, Taylan; Şanli-Mohameda, Gülşa (2011). Immobilization and characterization of recombinant esterase enzyme on chitosan nanoparticles. Journal of macromolecular science. Part A - pure and applied chemistry, 48(9), pp. 713-721. Taylor & Francis 10.1080/10601325.2011.596050

Sigel, E (2010). Microinjection into Xenopus oocytes. In: Encyclopedia of Life Sciences. Chichester: John Wiley & Sons Ltd 10.1002/9780470015902.a0002658.pub2

Feyen, Fabian; Cachoux, Frédéric; Gertsch, Jürg; Wartmann, Markus; Altmann, Karl-Heinz (2008). Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization. Accounts of chemical research, 41(1), pp. 21-31. Easton, Pa.: American Chemical Society 10.1021/ar700157x

Yes

Gertsch, Jürg; Chicca, Andrea (2024). CNS Drug Discovery in Academia: Where Basic Research Meets Innovation. ChemBioChem, 25(19), e202400397. Wiley 10.1002/cbic.202400397

Kroll, Sara L; Meier, Philip; Mayo, Leah M; Gertsch, Jürg; Quednow, Boris B (2024). Endocannabinoids and related lipids linked to social exclusion in individuals with chronic non-medical prescription opioid use. Neuropsychopharmacology, 49(10), pp. 1630-1639. Springer Nature 10.1038/s41386-024-01881-8

Mistry, Hiten D; Klossner, Rahel; Scaife, Paula J; Eisele, Nicole; Kurlak, Lesia O; Kallol, Sampada; Albrecht, Christiane; Gennari-Moser, Carine; Briggs, Louise V; Broughton Pipkin, Fiona; Mohaupt, Markus G (2024). Alterations of Placental Sodium in Preeclampsia: Trophoblast Responses. Hypertension, 81(9), pp. 1924-1934. American Heart Association 10.1161/HYPERTENSIONAHA.124.23001

Hirschi, Stephan; Lemmin, Thomas; Ayoub, Nooraldeen; Kalbermatter, David; Pellegata, Daniele; Ucurum, Zöhre; Gertsch, Jürg; Fotiadis, Dimitrios (2024). Structural insights into the mechanism and dynamics of proteorhodopsin biogenesis and retinal scavenging. Nature Communications, 15(1), p. 6950. Springer Nature 10.1038/s41467-024-50960-3

Chicca, Andrea; Bátora, Daniel; Ullmer, Christoph; Caruso, Antonello; Grüner, Sabine; Fingerle, Jürgen; Hartung, Thomas; Degen, Roland; Müller, Matthias; Grether, Uwe; Pacher, Pal; Gertsch, Jürg (2024). A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. ACS pharmacology & translational science, 7(8), pp. 2424-2438. ACS Publications 10.1021/acsptsci.4c00269

Lazaridi, Symela; Yuan, Jing; Lemmin, Thomas (2024). Atomic insights into the signaling landscape of E. coli PhoQ histidine kinase from molecular dynamics simulations. Scientific reports, 14(1), p. 17659. Springer Nature 10.1038/s41598-024-68206-z

Bátora, Dániel; Dienes-Nagy, Ágnes; Zeng, Liming; Gerber, Christian E.; Fischer, Jérôme P.; Lochner, Martin; Gertsch, Jürg (2024). Hypersensitive quantification of major astringency markers in food and wine by substoichiometric quenching of silicon-rhodamine conjugates. Food Chemistry: X, 23, p. 101592. Elsevier 10.1016/j.fochx.2024.101592

Tomašević, Nataša; Emser, Fabiola Susanna; Muratspahić, Edin; Gattringer, Jasmin; Hasinger, Simon; Hellinger, Roland; Keov, Peter; Felkl, Manuel; Gertsch, Jürg; Becker, Christian F W; Gruber, Christian W (2024). Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor. The journal of biological chemistry, 300(6), p. 107330. American Society for Biochemistry and Molecular Biology 10.1016/j.jbc.2024.107330

Chicca, Andrea; Batora, Daniel; Ullmer, Christoph; Caruso, Antonello; Fingerle, Jürgen; Hartung, Thomas; Degen, Roland; Müller, Matthias; Grether, Uwe; Pacher, Pal; Gertsch, Jürg (29 April 2024). A highly potent, orally bioavailable pyrazole-derived cannabinoid CB2 receptor-selective full agonist for in vivo studies. (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2024.04.26.591311

Dawoody Nejad, Ladan; Annese, Tiziana; Ribatti, Domenico (2024). Lysosomal diacylglycerol pyrophosphate phosphatase is not essential in Trypanosoma brucei. Molecular biology reports, 51(578) Springer 10.1007/s11033-024-09547-w

Bátora, Daniel; Fischer, Jérôme P.; Kaderli, Reto M.; Varga, Máté; Lochner, Martin; Gertsch, Jürg (2024). Silicon-Rhodamine Functionalized Evocalcet Probes Potently and Selectively Label Calcium Sensing Receptors In Vitro, In Vivo, and Ex Vivo. ACS pharmacology & translational science, 7(5), pp. 1557-1570. ACS Publications 10.1021/acsptsci.4c00096

Schröder, Mariana; Fuenzalida, Barbara; Yi, Nan; Shahnawaz, Saira; Gertsch, Jürg; Pellegata, Daniele; Ontsouka, Edgar; Leiva, Andrea; Gutiérrez, Jaime; Müller, Martin; Brocco, Marcela A; Albrecht, Christiane (2024). LAT1-dependent placental methionine uptake is a key player in fetal programming of metabolic disease. Metabolism : clinical and experimental, 153, p. 155793. Elsevier 10.1016/j.metabol.2024.155793

Harder, Daniel; Ritzmann, Noah; Ucurum Fotiadis, Zöhre; Müller, Daniel J; Fotiadis, Dimitrios (2024). Light Color-Controlled pH-Adjustment of Aqueous Solutions Using Engineered Proteoliposomes. Advanced science, 11(15), e2307524. Wiley 10.1002/advs.202307524

Zaugg, Jonas; Lopez-Tello, Jorge; Musial, Barbara; Vaughan, Owen R; Fowden, Abigail L; Albrecht, Christiane; Sferruzzi-Perri, Amanda N (2024). Obesogenic diet in pregnancy disrupts placental iron handling and ferroptosis and stress signalling in association with fetal growth alterations. Cellular and molecular life sciences : CMLS, 81(151) Springer 10.1007/s00018-024-05192-5

Kappel, Sven; Melek, Korollus; Ross-Kaschitza, Daniela; Hauert, Barbara; Gerber, Christian E.; Lochner, Martin; Peinelt, Christine (2024). CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells. Frontiers in Pharmacology, 15 Frontiers 10.3389/fphar.2024.1369513

McCafferty, Caitlyn L; Klumpe, Sven; Amaro, Rommie E; Kukulski, Wanda; Collinson, Lucy; Engel, Benjamin D (2024). Integrating cellular electron microscopy with multimodal data to explore biology across space and time. Cell, 187(3), pp. 563-584. Elsevier 10.1016/j.cell.2024.01.005

Fuenzalida, Barbara; Yañez, Maria Jose; Mueller, Martin; Mistry, Hiten D; Leiva, Andrea; Albrecht, Christiane (2024). Evidence for hypoxia-induced dysregulated cholesterol homeostasis in preeclampsia: Insights into the mechanisms from human placental cells and tissues. FASEB journal, 38(2) Federation of American Societies for Experimental Biology 10.1096/fj.202301708RR

Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; ... (2024). Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 263(115916), p. 115916. Elsevier 10.1016/j.ejmech.2023.115916

Tscherrig, Dominic; Bhardwaj, Rajesh; Biner, Daniel; Dernič, Jan; Ross-Kaschitza, Daniela; Peinelt, Christine; Hediger, Matthias A; Lochner, Martin (2024). Development of chemical tools based on GSK-7975A to study store-operated calcium entry in cells. Cell calcium, 117, p. 102834. Elsevier 10.1016/j.ceca.2023.102834

Fuenzalida, Barbara; Albrecht, Christiane (2024). Assessing Cholesterol Efflux on Primary Human Trophoblast Cells. Methods in molecular biology, 2728, pp. 123-129. Springer 10.1007/978-1-0716-3495-0_10

Zaugg, Jonas; Albrecht, Christiane (2024). Assessment of Placental Sodium-Independent Leucine Uptake and Transfer in Trophoblast Cells. Methods in molecular biology, 2728, pp. 105-121. Springer 10.1007/978-1-0716-3495-0_9

Jayakumar, Remya; Dash, Manoj Kumar; Kumar, Pankaj; Sharma, Shiwakshi; Gulati, Saumya; Pandey, Akanksha; Cholke, Kaushavi; Fatima, Zeeshan; Trigun, S K; Joshi, Namrata (2024). Pharmaceutical characterization and exploration of Arkeshwara rasa in MDA-MB-231 cells. Journal of Ayurveda and integrative medicine, 15(1), p. 100823. Elsevier 10.1016/j.jaim.2023.100823

Iamshanova, Oksana; Hämmerli, Anne-Flore; Ramaye, Elise; Seljmani, Arbresh; Ross-Kaschitza, Daniela; Schärz, Noëlia; Essers, Maria; Guichard, Sabrina; Rougier, Jean-Sébastien; Abriel, Hugues (2024). The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5. PLoS ONE, 19(3) Public Library of Science 10.1371/journal.pone.0298820

Rodella, Chiara; Lazaridi, Symela; Lemmin, Thomas (2024). TemBERTure: advancing protein thermostability prediction with deep learning and attention mechanisms. Bioinformatics advances, 4(1) Oxford University Press 10.1093/bioadv/vbae103

Liu, Yangci; Zhai, Haoming; Alemayehu, Helen; Boulanger, Jérôme; Hopkins, Lee J; Borgeaud, Alicia C; Heroven, Christina; Howe, Jonathan D; Leigh, Kendra E; Bryant, Clare E; Modis, Yorgo (2023). Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization. Nature communications, 14(1), p. 7246. Nature Publishing Group 10.1038/s41467-023-43180-8

Reiners, Johanna Christina; Leopold, Laura; Hallebach, Vera; Sinske, Daniela; Meier, Philip; Amoroso, Mattia; Langgartner, Dominik; Reber, Stefan O; Knöll, Bernd (2023). Acute stress modulates the outcome of traumatic brain injury-associated gene expression and behavioral responses. FASEB journal, 37(11), e23218. Federation of American Societies for Experimental Biology 10.1096/fj.202301035R

Wang, Lei; Bütikofer, Peter (2023). Lactose Permease Scrambles Phospholipids. Biology, 12(11) MDPI 10.3390/biology12111367

Jiang, Shan; Steup, Lydia C; Kippnich, Charlotte; Lazaridi, Symela; Malengo, Gabriele; Lemmin, Thomas; Yuan, Jing (2023). The inhibitory mechanism of a small protein reveals its role in antimicrobial peptide sensing. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 120(41), e2309607120. National Academy of Sciences 10.1073/pnas.2309607120

Papapostolou, Irida; Bochen, Florian; Peinelt, Christine; Maldifassi, Maria Constanza (2023). A Simple and Fast Method for the Formation and Downstream Processing of Cancer-Cell-Derived 3D Spheroids: An Example Using Nicotine-Treated A549 Lung Cancer 3D Spheres. Methods and protocols, 6(5) MDPI AG 10.3390/mps6050094

Alexander, Stephen P H; Fabbro, Doriano; Kelly, Eamonn; Mathie, Alistair A; Peters, John A; Veale, Emma L; Armstrong, Jane F; Faccenda, Elena; Harding, Simon D; Davies, Jamie A; Annett, Stephanie; Boison, Detlev; Burns, Kathryn Elisa; Dessauer, Carmen; Gertsch, Jurg; Helsby, Nuala Ann; Izzo, Angelo A; Ostrom, Rennolds; Papapetropoulos, Andreas; Pyne, Nigel J; ... (2023). The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. British journal of pharmacology, 180 Suppl 2, S289-S373. Wiley-Blackwell 10.1111/bph.16181

Maccarrone, Mauro; Di Marzo, Vincenzo; Gertsch, Juerg; Grether, Uwe; Howlett, Allyn C; Hua, Tian; Makriyannis, Alexandros; Piomelli, Daniele; Ueda, Natsuo; van der Stelt, Mario (2023). Goods and bads of endocannabinoid system as a therapeutic target: Lessons learned after 30 years. Pharmacological reviews, 75(5), pp. 885-958. American Society for Pharmacology and Experimental Therapeutics 10.1124/pharmrev.122.000600

Krishnan, Sandhya R; Skiba, Adrianna; Luca, Simon Vlad; Marcourt, Laurence; Wolfender, Jean-Luc; Skalicka-Woźniak, Krystyna; Gertsch, Jürg (2023). Bioactivity-guided isolation of trypanocidal coumarins and dihydro-pyranochromones from selected Apiaceae plant species. Phytochemistry, 213, p. 113770. Elsevier 10.1016/j.phytochem.2023.113770

Gertsch, Jürg; Heilmann, Jörg; Skaltsa, Eleni (2023). Editorial. Phytochemistry, 213(113781), p. 113781. Elsevier 10.1016/j.phytochem.2023.113781

Selimi, Zoja; Rougier, Jean-Sébastien; Abriel, Hugues; Kucera, Jan P (2023). A detailed analysis of single-channel Nav 1.5 recordings does not reveal any cooperative gating. The journal of physiology, 601(17), pp. 3847-3868. The Physiological Society 10.1113/JP284861

Thompson, Danielle; Cismaru, Christiana Victoria; Rougier, Jean-Sébastien; Schwemmle, Martin; Zimmer, Gert (2023). The M2 proteins of bat influenza A viruses reveal atypical features compared to conventional M2 proteins. Journal of virology, 97(8), e0038823. American Society for Microbiology 10.1128/jvi.00388-23

Fischer, Jérôme Paul; Bátora, Dániel; Dick, Luca Julian; Kaderli, Reto Martin; Gertsch, Jürg; Lochner, Martin (8 August 2023). Developing Molecular Tools for the Study and Detection of Calcium-Sensing Receptor [MC-112]. CHIMIA, 77(7/8), p. 526. Schweizerische Chemische Gesellschaft

Gerber, Christian Elias; Grossenbacher, Philipp; Singer, Simon Alex; Lochner, Martin (8 August 2023). Development of novel 4-chloro-2-(2-phenoxyacetamido)benzoic acid-based TRPM4 inhibitors [MC-115]. CHIMIA, 77(7/8), p. 526. Schweizerische Chemische Gesellschaft

Papapostolou, Irida; Ross, Daniela; Bochen, Florian; Peinelt, Christine; Maldifassi, Maria Constanza (2023). Contribution of the α5 nAChR Subunit and α5SNP to Nicotine-Induced Proliferation and Migration of Human Cancer Cells. Cells, 12(15) MDPI 10.3390/cells12152000

Khaddaj, Rasha; Kukulski, Wanda (2023). Piecing together the structural organisation of lipid exchange at membrane contact sites. Current opinion in cell biology, 83, p. 102212. Elsevier 10.1016/j.ceb.2023.102212

Arullampalam, Prakash; Essers, Maria C; Boukenna, Mey; Guichard, Sabrina; Rougier, Jean-Sébastien; Abriel, Hugues (2023). Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex- and age-dependent manner in mice. Physiological reports, 11(16), e15783. The American Physiological Society 10.14814/phy2.15783

Iamshanova, Oksana; Rougier, Jean-Sébastien; Abriel, Hugues (2023). Exploring the Oligomerization of Nav1.5 and Its Implication for the Dominant-Negative Effect. Bioelectricity, 5(4), pp. 279-289. Mary Ann Liebert 10.1089/bioe.2023.0014

Skiba, Adrianna; Pellegata, Daniele; Morozova, Veronika; Kozioł, Ewelina; Budzyńska, Barbara; Lee, Simon Ming-Yuen; Gertsch, Jürg; Skalicka-Woźniak, Krystyna (2023). Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation. Cells, 12(11) MDPI 10.3390/cells12111540

Maldifassi, Maria Constanza; Campello, Hugo Rego; Gallagher, Timothy; Lester, Henry A; Dougherty, Dennis A (2023). Human α6β4 nicotinic acetylcholine receptor: heterologous expression and agonist behavior provide insights into the immediate binding site. Molecular pharmacology, 103(6), pp. 339-347. American Society for Pharmacology and Experimental Therapeutics 10.1124/molpharm.123.000672

Wozny, Michael R; Di Luca, Andrea; Morado, Dustin R; Picco, Andrea; Khaddaj, Rasha; Campomanes, Pablo; Ivanović, Lazar; Hoffmann, Patrick C; Miller, Elizabeth A; Vanni, Stefano; Kukulski, Wanda (2023). In situ architecture of the ER-mitochondria encounter structure. Nature, 618(7963), pp. 188-192. Macmillan Journals Ltd. 10.1038/s41586-023-06050-3

Ontsouka, Edgar; Schroeder, Mariana; Ok, Linda; Vaillancourt, Cathy; Stroka, Deborah; Albrecht, Christiane (2023). The Placenta-A New Source of Bile Acids during Healthy Pregnancy? First Results of a Gene Expression Study in Humans and Mice. International journal of molecular sciences, 24(11) MDPI 10.3390/ijms24119511

Kara, Nilufer; Ayoub, Nooraldeen; Ilgu, Huseyin; Fotiadis, Dimitrios; Ilgu, Muslum (2023). Aptamers Targeting Membrane Proteins for Sensor and Diagnostic Applications. Molecules, 28(9) MDPI 10.3390/molecules28093728

Boukenna, Mey; Rougier, Jean-Sébastien; Aghagolzadeh, Parisa; Pradervand, Sylvain; Guichard, Sabrina; Hämmerli, Anne-Flore; Pedrazzini, Thierry; Abriel, Hugues (2023). Multiomics uncover the pro-inflammatory role of Trpm4 deletion after myocardial infarction in mice. American journal of physiology - heart and circulatory physiology, 324(4), H504-H518. American Physiological Society 10.1152/ajpheart.00671.2022

Ayoub, Nooraldeen; Roth, Patrick; Ucurum, Zöhre; Fotiadis, Dimitrios; Hirschi, Stephan (2023). Structural and biochemical insights into His-tag-induced higher-order oligomerization of membrane proteins by cryo-EM and size exclusion chromatography. Journal of structural biology, 215(1), p. 107924. Elsevier 10.1016/j.jsb.2022.107924

Ganeva, Iva; Lim, Koini; Boulanger, Jerome; Hoffmann, Patrick C; Muriel, Olivia; Borgeaud, Alicia C; Hagen, Wim J H; Savage, David B; Kukulski, Wanda (2023). The architecture of Cidec-mediated interfaces between lipid droplets. Cell reports, 42(2), p. 112107. Cell Press 10.1016/j.celrep.2023.112107

Kalbermatter, David; Jeckelmann, Jean-Marc; Wyss, Marianne; Shrestha, Neeta; Pliatsika, Dimanthi; Riedl, Rainer; Lemmin, Thomas; Plattet, Philippe; Fotiadis, Dimitrios (2023). Structure and supramolecular organization of the canine distemper virus attachment glycoprotein. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 120(6), e2208866120. National Academy of Sciences NAS 10.1073/pnas.2208866120

Kolatt Chandran, Sailendrakumar; Yiannakas, Adonis; Kayyal, Haneen; Salalha, Randa; Cruciani, Federica; Mizrahi, Liron; Khamaisy, Mohammad; Stern, Shani; Rosenblum, Kobi (2023). Intrinsic excitability in layer IV-VI anterior insula to basolateral amygdala projection neurons correlates with the confidence of taste valence encoding. eNeuro, 10(1) Society for Neuroscience 10.1523/ENEURO.0302-22.2022

Reynoso-Moreno, Ines; Rau, Mark; Chicca, Andrea; Nicolussi, Simon; Gertsch, Jürg (2023). Assay of Endocannabinoid Uptake. Methods in molecular biology, 2576, pp. 329-348. Springer 10.1007/978-1-0716-2728-0_28

Kantipudi, Satish; Harder, Daniel; Fotiadis, Dimitrios (2023). Characterization of substrates and inhibitors of the human heterodimeric transporter 4F2hc-LAT1 using purified protein and the scintillation proximity radioligand binding assay. Frontiers in physiology, 14(1148055), p. 1148055. Frontiers Research Foundation 10.3389/fphys.2023.1148055

Ontsouka, Edgar; Schröder, Mariana; Albrecht, Christiane (2023). Revisited role of the placenta in bile acid homeostasis. Frontiers in physiology, 14(1213757), p. 1213757. Frontiers Research Foundation 10.3389/fphys.2023.1213757

EL Makhzen, Nada; Daimi, Houria; Bouguenouch, Laila; Abriel, Hugues (2023). The burden of cystic fibrosis in North Africa. Frontiers in genetics, 14 Frontiers Media SA 10.3389/fgene.2023.1295008

Preti, Barbara; Rougier, Jean-Sébastien; Papapostolou, Irida; Bochen, Florian; Gerber, Christian E; Abriel, Hugues; Lochner, Martin; Peinelt, Christine (2022). Targeting Ion Channel TRPM4. CHIMIA, 76(12), pp. 1039-1044. Schweizerische Chemische Gesellschaft 10.2533/chimia.2022.1039

Zaugg, Jonas; Pujol Giménez, Jonai; Cabra, Romina Silvia; Hofstetter, Wilhelm; Hediger, Matthias; Albrecht, Christiane (2022). New Insights into the Physiology of Iron Transport: An Interdisciplinary Approach. CHIMIA, 76(12), pp. 996-1004. 10.2533/chimia.2022.996

Jeckelmann, Jean-Marc; Zaugg, Jonas; Morozova, Veronika; Müller, Jennifer; Kantipudi, Satish; Schröder, Mariana; Graff, Julien; Albrecht, Christiane; Altmann, Karl-Heinz; Gertsch, Jürg; Fotiadis, Dimitrios (2022). Structure, Function and Pharmacology of SLC7 Family Members and Homologues. CHIMIA, 76(12), pp. 1011-1018. Schweizerische Chemische Gesellschaft 10.2533/chimia.2022.1011

Rossetti, Valentina; Abriel, Hugues (2022). The NCCR TransCure: An Incubator for Interdisciplinary Research. CHIMIA, 76(12), pp. 992-995. Schweizerische Chemische Gesellschaft 10.2533/chimia.2022.992

Abriel, Hugues; Reymond, Jean-Louis (2022). NCCR TransCure - Excellence in Membrane Transport Research from 2010 until 2022. CHIMIA, 76(12), p. 989. Schweizerische Chemische Gesellschaft

Preti, Barbara; Suchankova, Anna; Deganutti, Giuseppe; Leuenberger, Michele; Barkan, Kerry; Manulak, Iga; Huang, Xianglin; Carvalho, Sabrina; Ladds, Graham; Lochner, Martin (2022). Discovery and Structure-Activity Relationship Studies of Novel Adenosine A1 Receptor-Selective Agonists. Journal of medicinal chemistry, 65(21), pp. 14864-14890. American Chemical Society 10.1021/acs.jmedchem.2c01414

Hirschi, Stephan; Ward, Thomas R; Meier, Wolfgang P; Müller, Daniel J; Fotiadis, Dimitrios (2022). Synthetic Biology: Bottom-Up Assembly of Molecular Systems. Chemical reviews, 122(21), pp. 16294-16328. American Chemical Society 10.1021/acs.chemrev.2c00339

Melero, Alejandro; Boulanger, Jerome; Kukulski, Wanda; Miller, Elizabeth A (2022). Ultrastructure of COPII vesicle formation in yeast characterised by correlative light and electron microscopy. Molecular biology of the cell, 33(13), ar122. American Society for Cell Biology 10.1091/mbc.E22-03-0103

Jeckelmann, Jean-Marc; Lemmin, Thomas; Schlapschy, Martin; Skerra, Arne; Fotiadis, Dimitrios (2022). Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM. Scientific reports, 12(1), p. 18269. Springer Nature 10.1038/s41598-022-23270-1

Grossenbacher, Philipp; Essers, Maria C; Moser, Joël; Singer, Simon A; Häusler, Stephanie; Stieger, Bruno; Rougier, Jean-Sébastien; Lochner, Martin (2022). Bioorthogonal site-selective conjugation of fluorescent dyes to antibodies: method and potential applications. RSC advances, 12(44), pp. 28306-28317. Royal Society of Chemistry 10.1039/d2ra05580e

Abou Hamdan, Abbas; Mahler, Roman; Grossenbacher, Philipp; Biner, Olivier; Sjöstrand, Dan; Lochner, Martin; Högbom, Martin; von Ballmoos, Christoph (2022). Functional design of bacterial superoxide:quinone oxidoreductase. Biochimica et biophysica acta. Bioenergetics, 1863(7), p. 148583. Elsevier 10.1016/j.bbabio.2022.148583

Kappel, Sven; Peinelt, Christine (2022). Targeting CRAC channels in inflammatory bowel disease. EMBO molecular medicine, 14(9), e16489. EMBO Press 10.15252/emmm.202216489

Graff, Julien; Müller, Jennifer; Sadurní, Anna; Rubin, Matthias; Cuissa, Inês André Canivete; Keller, Claudia; Hartmann, Marco; Singer, Simon; Gertsch, Jürg; Altmann, Karl-Heinz (2022). The Evaluation of L-Tryptophan Derivatives as Inhibitors of the LType Amino Acid Transporter LAT1 (SLC7A5). ChemMedChem, 17(17), e202200308. Wiley-VCH 10.1002/cmdc.202200308

Ruggeri, Francesca; Schwemmer, Christian; Stauffer, Mirko; Nicollier, Philippe; Figueiredo da Silva, Jacqueline; Bosshart, Patrick D; Kochems, Kirstin; Fotiadis, Dimitrios; Knoll, Armin; Wolf, Heiko (2022). Placement of Biological Membrane Patches in a Nanofluidic Gap With Control Over Position and Orientation. Advanced materials interfaces, 9(23), p. 2200941. Wiley 10.1002/admi.202200941

Vachalova, Veronika; Karahoda, Rona; Ottaviani, Martina; Anandam, Kasin Yadunandam; Abad, Cilia; Albrecht, Christiane; Staud, Frantisek (2022). Functional reorganization of monoamine transport systems during villous trophoblast differentiation: evidence of distinct differences between primary human trophoblasts and BeWo cells. Reproductive biology and endocrinology, 20(1), p. 112. BioMed Central 10.1186/s12958-022-00981-8

Zaugg, Jonas; Solenthaler, Fabia Sina; Albrecht, Christiane (2022). Materno-fetal iron transfer and the emerging role of ferroptosis pathways. Biochemical pharmacology, 202, p. 115141. Elsevier 10.1016/j.bcp.2022.115141

Schneider, Henning; Albrecht, Christiane; Ahmed, Mahmoud S; Broekhuizen, Michelle; Aengenheister, Leonie; Buerki-Thurnherr, Tina; Danser, A H Jan; Gil, Sophie; Hansson, Stefan R; Greupink, Rick; Lewis, Rohan M; Markert, Udo R; Mathiesen, Line; Powles-Glover, Nicola; Wadsack, Christian; Brownbill, Paul (2022). Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability. Placenta, 126, pp. 83-89. Elsevier 10.1016/j.placenta.2022.05.003

Wall, Mark J; Hill, Emily; Huckstepp, Robert; Barkan, Kerry; Deganutti, Giuseppe; Leuenberger, Michele; Preti, Barbara; Winfield, Ian; Carvalho, Sabrina; Suchankova, Anna; Wei, Haifeng; Safitri, Dewi; Huang, Xianglin; Imlach, Wendy; La Mache, Circe; Dean, Eve; Hume, Cherise; Hayward, Stephanie; Oliver, Jess; Zhao, Fei-Yue; ... (2022). Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression. Nature communications, 13(1), p. 4150. Nature Publishing Group 10.1038/s41467-022-31652-2

Augustynek, Bartlomiej; Gyimesi, Gergely; Dernič, Jan; Sallinger, Matthias; Albano, Giuseppe; Klesse, Gabriel J; Kandasamy, Palanivel; Grabmayr, Herwig; Frischauf, Irene; Fuster, Daniel G; Peinelt, Christine; Hediger, Matthias A; Bhardwaj, Rajesh (2022). Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs. Cell calcium, 105, p. 102616. Elsevier 10.1016/j.ceca.2022.102616

Fischer, Jérôme; Batora, Daniel; Kaderli, Reto Martin; Gertsch, Jürg; Lochner, Martin (July 2022). Developing Molecular Tools for the Study and Detection of Calcium-Sensing Receptor (CaSR) in Parathyroid Glands [MC-112]. CHIMIA, 76(7/8), p. 693. Schweizerische Chemische Gesellschaft

Grossenbacher, Philipp; Lochner, Martin (July 2022). Rapid Synthesis of Trifunctionalised Chemical Biology Probe from Unprotected L-Cysteine [MC-115]. CHIMIA, 76(7/8), p. 693. Schweizerische Chemische Gesellschaft

Fuenzalida, Barbara; Kallol, Sampada; Zaugg, Jonas; Müller, Martin; Mistry, Hiten D; Gutierrez, Jaime; Leiva, Andrea; Albrecht, Christiane (2022). Primary Human Trophoblasts Mimic the Preeclampsia Phenotype after Acute Hypoxia-Reoxygenation Insult. Cells, 11(12) MDPI 10.3390/cells11121898

Mistry, Hiten D; Klossner, Rahel; Kallol, Sampada; Lüthi, Michael P; Moser, Ruedi; Schneider, Henning; Ontsouka, Edgar C; Kurlak, Lesia O; Mohaupt, Markus G.; Albrecht, Christiane (2022). Effects of aldosterone on the human placenta: Insights from placental perfusion studies. Placenta, 123, pp. 32-40. Elsevier 10.1016/j.placenta.2022.03.129

Dokshokova, Lolita; Franzoso, Mauro; Bona, Anna Di; Moro, Nicola; Sanchez-Alonso-Mardones, Josè; Prando, Valentina; Sandre, Michele; Basso, Cristina; Faggian, Giuseppe; Abriel, Hugues; Marin, Oriano; Gorelik, Julia; Zaglia, Tania; Mongillo, Marco (2022). Nerve Growth Factor transfer from cardiomyocytes to innervating sympathetic neurons activates TrkA receptors at the neuro-cardiac junction. The journal of physiology, 600(12), pp. 2853-2875. The Physiological Society 10.1113/JP282828

Kappel, Sven; Ross, Daniela; Hauert, Barbara; Rother, Karen; Peinelt, Christine (2022). p53 alters intracellular Ca2+ signaling through regulation of TRPM4. Cell calcium, 104(102591), p. 102591. Elsevier 10.1016/j.ceca.2022.102591

Stokłosa, Paulina; Kappel, Sven; Peinelt, Christine (2022). A Novel Role of the TRPM4 Ion Channel in Exocytosis. Cells, 11(11) MDPI 10.3390/cells11111793

Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg and Tuccinardi, Tiziano (2022). Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives. Journal of medicinal chemistry, 65(10), pp. 7118-7140. American Chemical Society 10.1021/acs.jmedchem.1c01806

Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Korn, Claudia; Sykes, David; Forn-Cuni, Gabriel; Pfaff, Patrick; Sarott, Roman C; Westphal, Matthias V; Mostinski, Yelena; Mach, Leonard; Wasinska-Kalwa, Malgorzata; Weise, Marie; Hoare, Bradley L; Miljuš, Tamara; Mexi, Maira; Roth, Nicolas; Koers, Eline J; Guba, Wolfgang; Alker, André; ... (2022). Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe. Chemical Science, 13(19), pp. 5539-5545. The Royal Society of Chemistry 10.1039/d1sc06659e

Iyer, Advaitha Subramanyam; Niemann, Moritz; Serricchio, Mauro; Dewar, Caroline E; Oeljeklaus, Silke; Farine, Luce; Warscheid, Bettina; Schneider, André; Bütikofer, Peter (2022). The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei. PLoS pathogens, 18(5), e1009717. Public Library of Science 10.1371/journal.ppat.1009717

Hinden, Liad; Ahmad, Majdoleen; Hamad, Sharleen; Nemirovski, Alina; Szanda, Gergő; Glasmacher, Sandra; Kogot-Levin, Aviram; Abramovitch, Rinat; Thorens, Bernard; Gertsch, Jürg; Leibowitz, Gil; Tam, Joseph (2022). Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function. Nature Communications, 13(1), p. 1783. Springer Nature 10.1038/s41467-022-29124-8

Knüsel, Sebastian; Jenni, Aurelio; Benninger, Mattias; Bütikofer, Peter; Roditi, Isabel (2022). Persistence of Trypanosoma brucei as early procyclic forms and social motility are dependent on glycosylphosphatidylinositol transamidase. Molecular microbiology, 117(4), pp. 802-817. Wiley 10.1111/mmi.14873

Farfariello, Valerio; Gordienko, Dmitri V; Mesilmany, Lina; Touil, Yasmine; Germain, Emmanuelle; Fliniaux, Ingrid; Desruelles, Emilie; Gkika, Dimitra; Roudbaraki, Morad; Shapovalov, George; Noyer, Lucile; Lebas, Mathilde; Allart, Laurent; Zienthal-Gelus, Nathalie; Iamshanova, Oksana; Bonardi, Franck; Figeac, Martin; Laine, William; Kluza, Jerome; Marchetti, Philippe; ... (2022). TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence. Nature Communications, 13(1), p. 956. Springer Nature 10.1038/s41467-022-28597-x

Lüscher, Benjamin P.; Albrecht, Christiane; Stieger, Bruno; Surbek, Daniel V.; Baumann, Marc U. (2022). Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System. Cells, 11(4) MDPI 10.3390/cells11040633

Cowton, Andrew; Bütikofer, Peter; Häner, Robert; Menon, Anant K (2022). Identification of TbPBN1 in Trypanosoma brucei reveals a conserved heterodimeric architecture for glycosylphosphatidylinositol-mannosyltransferase I. Molecular microbiology, 117(2), pp. 450-461. Wiley 10.1111/mmi.14859

Kowalczyk, Joanna; Budzyńska, Barbara; Kurach, Łukasz; Pellegata, Daniele; El Sayed, Nesrine S; Gertsch, Jürg; Skalicka-Woźniak, Krystyna (2022). Neuropsychopharmacological profiling of scoparone in mice. Scientific reports, 12(1), p. 822. Springer Nature 10.1038/s41598-021-04741-3

Andrieu, Thomas; Chicca, Andrea; Pellegata, Daniele; Bersinger, Nick A.; Imboden, Sara; Nirgianakis, Konstantinos; Gertsch, Jürg; Mueller, Michael D. (2022). Association of endocannabinoids with pain in endometriosis. Pain, 163(1), pp. 193-203. Elsevier 10.1097/j.pain.0000000000002333

Karahoda, Rona; Zaugg, Jonas; Fuenzalida, Barbara; Kallol, Sampada; Moser-Haessig, Ruedi; Staud, Frantisek; Albrecht, Christiane (2022). Trophoblast Differentiation Affects Crucial Nutritive Functions of Placental Membrane Transporters. Frontiers in cell and developmental biology, 10, p. 820286. Frontiers 10.3389/fcell.2022.820286

Loffreda, Alessio; Schlame, Michael; Bütikofer, Peter (2022). StaR-related lipid transfer-like domain-containing protein CLDP43 affects cardiolipin synthesis and mitochondrial function in Trypanosoma brucei. PLoS ONE, 17(4), e0259752. Public Library of Science 10.1371/journal.pone.0259752

Schroeder, Mariana; Badini, Gina; Sferruzzi-Perri, Amanda N; Albrecht, Christiane (2022). The Consequences of Assisted Reproduction Technologies on the Offspring Health Throughout Life: A Placental Contribution. Frontiers in cell and developmental biology, 10, p. 906240. Frontiers 10.3389/fcell.2022.906240

Stauffer, Mirko; Jeckelmann, Jean-Marc; Ilgü, Hüseyin; Ucurum, Zöhre; Boggavarapu, Rajendra; Fotiadis, Dimitrios (2022). Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Communications chemistry, 5(1) Springer Nature 10.1038/s42004-022-00636-0

Shrestha, Neeta; Gall, Flavio Max; Mathieu, Cyrille; Hierweger, Melanie Michaela; Brügger, Melanie; Alves, Marco P.; Vesin, Jonathan; Banfi, Damiano; Kalbermatter, David; Horvat, Branka; Chambon, Marc; Turcatti, Gerardo; Fotiadis, Dimitrios; Riedl, Rainer; Plattet, Philippe (2021). Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier. mBio, 12(6), e0262121. American Society for Microbiology 10.1128/mBio.02621-21

Li, Jin (2021). The Role of Autoantibodies in Arrhythmogenesis. Current cardiology reports, 23(1), p. 3. Springer 10.1007/s11886-020-01430-x

Serricchio, Mauro; Bütikofer, Peter (2021). A Conserved Mitochondrial Chaperone-Protease Complex Involved in Protein Homeostasis. Frontiers in Molecular Biosciences, 8, p. 767088. Frontiers 10.3389/fmolb.2021.767088

Shahnawaz, Saira; Nawaz, Usman Shah; Zaugg, Jonas; Hussain, Ghulam; Malik, Nadia; Dogar, Muhammad Zahoor-Ul-Hassan; Malik, Shoaib Ahmad; Albrecht, Christiane (2021). Dysregulated Autophagy Leads to Oxidative Stress and Aberrant Expression of ABC Transporters in Women with Early Miscarriage. Antioxidants, 10(11) MDPI 10.3390/antiox10111742

Stoklosa, Paulina; Borgström, Anna; Hauert, Barbara; Baur, Roland; Peinelt, Christine (2021). Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells. Cancers, 13(21) MDPI AG 10.3390/cancers13215400

Hoffmann, Patrick C; Giandomenico, Stefano L; Ganeva, Iva; Wozny, Michael R; Sutcliffe, Magdalena; Lancaster, Madeline A; Kukulski, Wanda (2021). Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids. eLife, 10 eLife Sciences Publications 10.7554/eLife.70269

Luca, Simon Vlad; Gaweł-Bęben, Katarzyna; Strzępek-Gomółka, Marcelina; Czech, Karolina; Trifan, Adriana; Zengin, Gokhan; Korona-Glowniak, Izabela; Minceva, Mirjana; Gertsch, Jürg; Skalicka-Woźniak, Krystyna (2021). Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the Genus Piper. Antioxidants, 10(10) MDPI 10.3390/antiox10101642

Anghel, Nicoleta; Müller, Joachim; Serricchio, Mauro; Jelk, Jennifer; Bütikofer, Peter; Boubaker, Ghalia; Imhof, Dennis; Ramseier, Jessica; Desiatkina, Oksana; Paunescu, Emilia; Braga, Sophie Marie-Pierre; Heller, Manfred; Furrer, Julien; Hemphill, Andrew (2021). Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei. International journal of molecular sciences, 22(19) MDPI 10.3390/ijms221910787

Zaugg, Jonas; Ziegler, Fabian; Nuoffer, Jean-Marc; Moser-Hässig, Ruedi; Albrecht, Christiane (2021). Counter-directed leucine gradient promotes amino acid transfer across the human placenta. The journal of nutritional biochemistry, 96, p. 108760. Elsevier 10.1016/j.jnutbio.2021.108760

Alexander, Stephen Ph; Fabbro, Doriano; Kelly, Eamonn; Mathie, Alistair; Peters, John A; Veale, Emma L; Armstrong, Jane F; Faccenda, Elena; Harding, Simon D; Pawson, Adam J; Southan, Christopher; Davies, Jamie A; Boison, Detlev; Burns, Kathryn Elisa; Dessauer, Carmen; Gertsch, Jürg; Helsby, Nuala Ann; Izzo, Angelo A; Koesling, Doris; Ostrom, Rennolds; ... (2021). THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. British journal of pharmacology, 178(Suppl. 1), S313-S411. Wiley 10.1111/bph.15542

Ontsouka, Edgar; Epstein, Alessandra; Kallol, Sampada; Zaugg, Jonas; Baumann, Marc; Schneider, Henning; Albrecht, Christiane (2021). Placental Expression of Bile Acid Transporters in Intrahepatic Cholestasis of Pregnancy. International journal of molecular sciences, 22(19) MDPI 10.3390/ijms221910434

Schafroth, Michael A; Mazzoccanti, Giulia; Reynoso-Moreno, Ines; Erni, Reto; Pollastro, Federica; Caprioglio, Diego; Botta, Bruno; Allegrone, Gianna; Grassi, Giulio; Chicca, Andrea; Gasparrini, Francesco; Gertsch, Jürg; Carreira, Erick M; Appendino, Giovanni (2021). Δ9-cis-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology. Journal of natural products, 84(9), pp. 2502-2510. American Chemical Society 10.1021/acs.jnatprod.1c00513

Ontsouka, Edgar; Lüthi, Michael; Zaugg, Jonas; Schroeder, Mariana; Albrecht, Christiane (2021). Establishment and validation of an approach allowing unequivocal fetal sex determination based on placental sex-specific genes. Placenta, 112, pp. 132-134. Elsevier 10.1016/j.placenta.2021.07.295

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Kalbermatter, David; Ucurum, Zöhre; Lemmin, Thomas; Fotiadis, Dimitrios (2021). High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding. BMC biology, 19(1), p. 179. BioMed Central 10.1186/s12915-021-01102-4

Stauffer, Mirko; Ucurum, Zöhre; Harder, Daniel; Fotiadis, Dimitrios (2021). Engineering and functional characterization of a proton-driven β-lactam antibiotic translocation module for bionanotechnological applications. Scientific reports, 11(1), p. 17205. Springer Nature 10.1038/s41598-021-96298-4

Borgström, Anna; Hauert, Barbara; Kappel, Sven; Zoni, Eugenio; Kiener, Mirjam; Stokłosa, Paulina; Baur, Roland; Spahn, Martin; Kruithof-de Julio, Marianna; Peinelt, Christine (2021). Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. Journal of molecular biology, 433(17), p. 166665. Elsevier 10.1016/j.jmb.2020.09.024

Jenni, Aurelio; Knüsel, Sebastian; Nagar, Rupa; Benninger, Mattias; Häner, Robert; Ferguson, Michael A J; Roditi, Isabel; Menon, Anant K; Bütikofer, Peter (2021). Elimination of GPI2 suppresses glycosylphosphatidylinositol GlcNAc transferase activity and alters GPI glycan modification in Trypanosoma brucei. The journal of biological chemistry, 297(2), p. 100977. American Society for Biochemistry and Molecular Biology 10.1016/j.jbc.2021.100977

Kantipudi, Satish; Harder, Daniel; Bonetti, Sara; Fotiadis, Dimitrios; Jeckelmann, Jean-Marc (2021). Pichia pastoris and the Recombinant Human Heterodimeric Amino Acid Transporter 4F2hc-LAT1: From Clone Selection to Pure Protein. Methods and protocols, 4(3) MDPI AG 10.3390/mps4030051

Arullampalam, Prakash; Preti, Barbara; Ross, Daniela; Lochner, Martin; Rougier, Jean-Sébastien; Abriel, Hugues (2021). Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors. Frontiers in Pharmacology, 12 Frontiers 10.3389/fphar.2021.712354

Brand, Michael; Wang, Lei; Agnello, Stefano; Gazzola, Silvia; Gall, Flavio M; Raguž, Luka; Kaiser, Marcel; Schmidt, Remo S; Ritschl, Amélie; Jelk, Jennifer; Hemphill, Andrew; Mäser, Pascal; Bütikofer, Peter; Adams, Michael; Riedl, Rainer (2021). Antiprotozoal Structure-Activity Relationships of Synthetic Leucinostatin Derivatives and Elucidation of their Mode of Action. Angewandte Chemie (International ed.), 60(28), pp. 15613-15621. Wiley-VCH 10.1002/anie.202102153

Hirschi, Stephan; Kalbermatter, David; Ucurum, Zöhre; Lemmin, Thomas; Fotiadis, Dimitrios (2021). Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin. Nature communications, 12(1), p. 4107. Nature Publishing Group 10.1038/s41467-021-24429-6

Grossenbacher, Philipp; Damala, P; Kunji, Edmund; Lochner, Martin (July 2021). Chemical Approaches to Stabilise the Structure of Mitochondrial Carrier AGC2 (SLC25A13) [MC-111]. CHIMIA, 75(7/8), p. 666. Schweizerische Chemische Gesellschaft

Preti, Barbara; Suchankova, Anna; Barkan, Kerry; Leuenberger, Michele; Ladds, Graham; Lochner, Martin (July 2021). Structure-activity relationship study to find novel potent and selective adenosine A1 receptor agonists [MC-125]. CHIMIA, 75(7/8), p. 667. Schweizerische Chemische Gesellschaft

Leuenberger, Michele; Häusler, Stephanie; Höhn, Vera; Euler, Adriana; Stieger, Bruno; Lochner, Martin (2021). Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters. Journal of pharmacology and experimental therapeutics, 377(3), pp. 346-357. American Society for Pharmacology and Experimental Therapeutics 10.1124/jpet.120.000449

Traversi, Florian; Stooss, Amandine; Dettmer, Matthias S.; Charles, Roch-Philippe (2021). BRAFV600E Overrides NOTCH Signaling in Thyroid Cancer. Thyroid, 31(5), pp. 787-799. Mary Ann Liebert 10.1089/thy.2019.0595

Wozny, Michael R; Kukulski, Wanda (2021). Molecular visualization of cellular complexity. Nature methods, 18(5), pp. 438-439. Springer Nature 10.1038/s41592-021-01131-5

Glasmacher, Sandra; Gertsch, Jürg (2021). Characterization of pepcan-23 as pro-peptide of RVD-hemopressin (pepcan-12) and stability of hemopressins in mice. Advances in biological regulation, 80, p. 100808. Elsevier 10.1016/j.jbior.2021.100808

Salm, Andrea; Krishnan, Sandhya R.; Collu, Marta; Danton, Ombeline; Hamburger, Matthias; Leonti, Marco; Almanza, Giovanna; Gertsch, Jürg (2021). Phylobioactive hotspots in plant resources used to treat Chagas disease. iScience, 24(4), p. 102310. Elsevier 10.1016/j.isci.2021.102310

Espinoza, Cristian; Fuenzalida, Barbara; Leiva, Andrea (2021). Increased Fetal Cardiovascular Disease Risk: Potential Synergy Between Gestational Diabetes Mellitus and Maternal Hypercholesterolemia. Current vascular pharmacology, 19(6), pp. 601-623. Bentham Science 10.2174/1570161119666210423085407

Gruber, Thomas; Robatel, Steve; Kremenovic, Mirela; Bäriswyl, Lukas; Gertsch, Jürg; Schenk, Mirjam (2021). Cannabinoid Receptor Type-2 in B Cells Is Associated with Tumor Immunity in Melanoma. Cancers, 13(8) MDPI AG 10.3390/cancers13081934

Reynoso-Moreno, Ines; Tietz, Silvia; Vallini, Erika; Engelhardt, Britta; Gertsch, Jürg; Chicca, Andrea (2021). Selective Endocannabinoid Reuptake Inhibitor WOBE437 Reduces Disease Progression in a Mouse Model of Multiple Sclerosis. ACS pharmacology & translational science, 4(2), pp. 765-779. ACS Publications 10.1021/acsptsci.0c00214

Altmann, Karl-Heinz; Bold, Christian Paul; Gut, Melanie; Schürmann, Jasmine; Lucena Agell, Daniel; Diaz, Jose Fernando; Gertsch, Jürg (2021). Synthesis of Morpholine-Based Analogs of (-)-Zampanolide and Their Biological Activity. Chemistry: a European journal, 27(19), pp. 5936-5943. Wiley 10.1002/chem.202003996

Schneider, Henning; Brownbill, Paul; Albrecht, Christiane (2021). Ex vivo dual perfusion of an isolated cotyledon of human placenta: History and future challenges. Placenta, 107, pp. 8-12. Elsevier 10.1016/j.placenta.2021.02.017

Ozhathil, Lijo Cherian; Rougier, Jean-Sébastien; Arullampalam, Prakash; Essers, Maria C.; Ross-Kaschitza, Daniela; Abriel, Hugues (2021). Deletion of Trpm4 Alters the Function of the Nav1.5 Channel in Murine Cardiac Myocytes. International journal of molecular sciences, 22(7) MDPI 10.3390/ijms22073401

Yan, Renhong; Li, Yaning; Müller, Jennifer; Zhang, Yuanyuan; Singer, Simon; Xia, Lu; Zhong, Xinyue; Gertsch, Jürg; Altmann, Karl-Heinz; Zhou, Qiang (2021). Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter. Cell discovery, 7(1), p. 16. Springer Nature 10.1038/s41421-021-00247-4

Hu, Yaopeng; Ross Kaschitza, Daniela; Essers, Maria; Arullampalam, Prakash; Fujita, Takayuki; Abriel, Hugues; Inoue, Ryuji (2021). Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation. Pflügers Archiv : European journal of physiology, 473(3), pp. 507-519. Springer 10.1007/s00424-020-02507-w

Luca, Simon Vlad; Minceva, Mirjana; Gertsch, Jürg; Skalicka-Wozniak, Krystyna Katarzyna (2021). LC-HRMS/MS-based phytochemical profiling of Piper spices: Global association of piperamides with endocannabinoid system modulation. Food research international, 141, p. 110123. Elsevier 10.1016/j.foodres.2021.110123

Karahoda, Rona; Kallol, Sampada; Groessl, Michael; Ontsouka, Edgar; Anderle, Pascale; Fluck, Christa; Staud, Frantisek; Albrecht, Christiane (2021). Revisiting Steroidogenic Pathways in the Human Placenta and Primary Human Trophoblast Cells. International journal of molecular sciences, 22(4) MDPI 10.3390/ijms22041704

Borgström, Anna; Peinelt, Christine; Stoklosa, Paulina (2021). TRPM4 in Cancer-A New Potential Drug Target. Biomolecules, 11(2) MDPI 10.3390/biom11020229

Serricchio, Mauro; Hierro-Yap, Carolina; Schädeli, David; Ben Hamidane, Hisham; Hemphill, Andrew; Graumann, Johannes; Zíková, Alena; Bütikofer, Peter (2021). Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms. FASEB journal, 35(2), e21176. Federation of American Societies for Experimental Biology 10.1096/fj.202001579RR

Schuele, Lena-Louise; Glasmacher, Sandra; Gertsch, Jürg; Roggan, Marie Denise; Transfeld, Janis-Lisa; Bindila, Laura; Lutz, Beat; Kolbe, Carl-Christian; Bilkei-Gorzo, Andras; Zimmer, Andreas; Leidmaa, Este (2021). Diacylglycerol lipase alpha in astrocytes is involved in maternal care and affective behaviors. GLIA, 69(2), pp. 377-391. Wiley 10.1002/glia.23903

Fuenzalida, Bárbara; Kallol, Sampada; Lüthi, Michael; Albrecht, Christiane; Leiva, Andrea (2021). The polarized localization of lipoprotein receptors and cholesterol transporters in the syncytiotrophoblast of the placenta is reproducible in a monolayer of primary human trophoblasts. Placenta, 105, pp. 50-60. Elsevier 10.1016/j.placenta.2021.01.019

Deganutti, Giuseppe; Barkan, Kerry; Preti, Barbara; Leuenberger, Michele; Wall, Mark; Frenguelli, Bruno G.; Lochner, Martin; Ladds, Graham; Reynolds, Christopher A. (2021). Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor. ACS pharmacology & translational science, 4(1), pp. 314-326. ACS Publications 10.1021/acsptsci.0c00195

Shrestha, Neeta; Gall, Flavio M; Vesin, Jonathan; Chambon, Marc; Turcatti, Gerardo; Fotiadis, Dimitrios; Riedl, Rainer; Plattet, Philippe (2021). Antiviral Screen against Canine Distemper Virus-Induced Membrane Fusion Activity. Viruses, 13(1) MDPI 10.3390/v13010128

Mäder, Patrick; Bartholomäus, Ruben; Nicolussi, Simon; Baumann, Alice; Weis, Melanie; Chicca, Andrea; Rau, Mark; Simão, Ana Catarina; Gertsch, Jürg; Altmann, Karl-Heinz (2021). Synthesis and Biological Evaluation of Endocannabinoid Uptake Inhibitors Derived from WOBE437. ChemMedChem, 16(1), pp. 145-154. Wiley-VCH 10.1002/cmdc.202000153

Granchi, Carlotta; Bononi, Giulia; Ferrisi, Rebecca; Gori, Eleonora; Mantini, Giulia; Glasmacher, Sandra; Poli, Giulio; Palazzolo, Stefano; Caligiuri, Isabella; Rizzolio, Flavio; Canzonieri, Vincenzo; Perin, Tiziana; Gertsch, Jürg; Sodi, Andrea; Giovannetti, Elisa; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea (2021). Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 209, p. 112857. Elsevier 10.1016/j.ejmech.2020.112857

Bosshart, Patrick D.; Charles, Roch-Philippe; Garibsingh, Rachel-Ann A; Schlessinger, Avner; Fotiadis, Dimitrios (2021). SLC16 Family: From Atomic Structure to Human Disease. Trends in biochemical sciences, 46(1), pp. 28-40. Elsevier Current Trends 10.1016/j.tibs.2020.07.005

Verchère, Alice; Cowton, Andrew; Jenni, Aurelio; Rauch, Monika; Häner, Robert; Graumann, Johannes; Bütikofer, Peter; Menon, Anant K. (2021). Complexity of the eukaryotic dolichol-linked oligosaccharide scramblase suggested by activity correlation profiling mass spectrometry. Scientific reports, 11(1), p. 1411. Springer Nature 10.1038/s41598-020-80956-0

Kantipudi, Satish; Fotiadis, Dimitrios José (2021). Yeast Cell-Based Transport Assay for the Functional Characterization of Human 4F2hc-LAT1 and -LAT2, and LAT1 and LAT2 Substrates and Inhibitors. Frontiers in Molecular Biosciences, 8(676854), p. 676854. Frontiers 10.3389/fmolb.2021.676854

Bosshart, Patrick D.; Kalbermatter, David; Bonetti, Sara; Fotiadis, Dimitrios (2021). The making of a potent L-lactate transport inhibitor. Communications chemistry, 4(1) Springer Nature 10.1038/s42004-021-00564-5

Amarouch, Mohamed-Yassine; Zaklyazminskaya, Elena V; Rougier, Jean-Sébastien (2021). Editorial: Inherited Arrhythmias of the Cardiac Sodium Channel Nav1.5. Frontiers in physiology, 12, p. 716553. Frontiers Research Foundation 10.3389/fphys.2021.716553

Arena, Chiara; Gado, Francesca; Di Cesare Mannelli, Lorenzo; Cervetto, Chiara; Carpi, Sara; Reynoso-Moreno, Ines; Polini, Beatrice; Vallini, Erika; Chicca, Stefano; Lucarini, Elena; Bertini, Simone; D'Andrea, Felicia; Digiacomo, Maria; Poli, Giulio; Tuccinardi, Tiziano; Macchia, Marco; Gertsch, Jürg; Marcoli, Manuela; Nieri, Paola; Ghelardini, Carla; ... (2020). The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis. European journal of medicinal chemistry, 208, p. 112858. Elsevier 10.1016/j.ejmech.2020.112858

Wang, Zizun; Vermij, Sarah H.; Sottas, Valentin; Shestak, Anna; Ross-Kaschitza, Daniela; Zaklyazminskaya, Elena V; Hudmon, Andy; Pitt, Geoffrey S; Rougier, Jean-Sébastien; Abriel, Hugues (2020). Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5. Channels, 14(1), pp. 268-286. Taylor & Francis 10.1080/19336950.2020.1805999

Miller, Sally; Daily, Laura; Dharla, Vijai; Gertsch, Jürg; Malamas, Michael S; Ojima, Iwao; Kaczocha, Martin; Ogasawara, Daisuke; Straiker, Alex (2020). Endocannabinoid metabolism and transport as targets to regulate intraocular pressure. Experimental eye research, 201, p. 108266. Elsevier 10.1016/j.exer.2020.108266

Bhardwaj, Rajesh; Lindinger, Sonja; Neuberger, Arthur; Nadezhdin, Kirill D.; Singh, Appu K.; R. Cunha, Micael; Derler, Isabella; Gyimesi, Gergely; Reymond, Jean-Louis; Hediger, Matthias A.; Romanin, Christoph; Sobolevsky, Alexander I. (2020). Inactivation-mimicking block of the epithelial calcium channel TRPV6. Science Advances, 6(48), eabe1508. American Association for the Advancement of Science 10.1126/sciadv.abe1508

Jeckelmann, Jean-Marc; Erni, Bernhard (2020). The mannose phosphotransferase system (Man-PTS) - Mannose transporter and receptor for bacteriocins and bacteriophages. Biochimica et biophysica acta : BBA. Biomembranes, 1862(11), p. 183412. Elsevier 10.1016/j.bbamem.2020.183412

Zaugg, Jonas; Huang, Xiao; Ziegler, Fabian; Rubin, Matthias; Graff, Julien; Müller, Jennifer; Moser-Hässig, Ruedi; Powell, Theresa; Gertsch, Jürg; Altmann, Karl-Heinz; Albrecht, Christiane (2020). Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno-foetal amino acid transport. Journal of cellular and molecular medicine, 24(21), pp. 12681-12693. Wiley 10.1111/jcmm.15840

Zurkinden, Line; Sviridov, Dmitri; Vogt, Bruno; Escher, Genevieve (2020). Downregulation of Cyp7a1 by Cholic Acid and Chenodeoxycholic Acid in Cyp27a1/ApoE Double Knockout Mice: Differential Cardiovascular Outcome. Frontiers in endocrinology, 11, p. 586980. Frontiers Research Foundation 10.3389/fendo.2020.586980

Kantipudi, Satish; Jeckelmann, Jean-Marc; Ucurum, Zöhre; Bosshart, Patrick D.; Fotiadis, Dimitrios (2020). The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2. International journal of molecular sciences, 21(20) MDPI 10.3390/ijms21207573

Sarott, Roman C; Westphal, Matthias V; Pfaff, Patrick; Korn, Claudia; Sykes, David A; Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Weise, Marie; Mostinski, Yelena; Hompluem, Pattarin; Koers, Eline; Miljuš, Tamara; Roth, Nicolas J; Asmelash, Hermon; Vong, Man C; Piovesan, Jacopo; Guba, Wolfgang; Rufer, Arne C; Kusznir, Eric A; ... (2020). Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells. Journal of the American Chemical Society, 142(40), pp. 16953-16964. American Chemical Society 10.1021/jacs.0c05587

Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2020). Sub-Nanometer Cryo-EM Density Map of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2. International journal of molecular sciences, 21(19) MDPI 10.3390/ijms21197094

Guha, Sujay; Calarco, Serafina; Gachet, M. Salomé; Gertsch, Jürg (2020). Juniperonic Acid Biosynthesis is Essential in Caenorhabditis Elegans Lacking Δ6 Desaturase (fat-3) and Generates New ω-3 Endocannabinoids. Cells, 9(9) MDPI 10.3390/cells9092127

Jeckelmann, Jean-Marc; Erni, Bernhard (2020). Transporters of glucose and other carbohydrates in bacteria. Pflügers Archiv : European journal of physiology, 472(9), pp. 1129-1153. Springer 10.1007/s00424-020-02379-0

Preti, Barbara; Leuenberger, Michele; Lochner, Martin (25 August 2020). Synthesis and characterization of an adenosine A1 receptor agonist with non-opioid analgesic properties based on Galpha signaling bias [MC-014]. CHIMIA, 74(7/8), p. 594. Schweizerische Chemische Gesellschaft

Grossenbacher, Philipp; Singer, Simon Alex; Moser, Joel; Stephanie A., Bernhard; Stieger, Bruno; Lochner, Martin (25 August 2020). Bioorthogonal site-selective conjugation of fluorescent dyes to antibodies: method and potential applications [MC-119]. CHIMIA, 74(7/8), p. 603. Schweizerische Chemische Gesellschaft

Lam, K.-T.; Taylor, E. L.; Thompson, Andrew James; Ruepp, Marc-David; Lochner, Martin; Martinez, M. J.; Brozik, James A. (2020). Direct Measurement of Single-Molecule Ligand-Receptor Interactions. Journal of physical chemistry - B, 124(36), pp. 7791-7802. American Chemical Society 10.1021/acs.jpcb.0c05474

Schild, Achille; Bhardwaj, Rajesh; Wenger, Nicolas; Tscherrig, Dominic; Kandasamy, Palanivel; Dernič, Jan; Baur, Roland; Peinelt, Christine; Hediger, Matthias A.; Lochner, Martin (2020). Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells. International journal of molecular sciences, 21(16) MDPI 10.3390/ijms21165604

Stauffer, Mirko; Hirschi, Stephan; Ucurum, Zöhre; Harder, Daniel; Schlesinger, Ramona; Fotiadis, Dimitrios (2020). Engineering and Production of the Light-Driven Proton Pump Bacteriorhodopsin in 2D Crystals for Basic Research and Applied Technologies. Methods and protocols, 3(3) MDPI AG 10.3390/mps3030051

Rodrigues Cunha, Micael; Bhardwaj, Rajesh; Carrel, Aline Lucie; Lindinger, Sonja; Romanin, Christoph; Parise-Filho, Roberto; Hediger, Matthias A.; Reymond, Jean-Louis (2020). Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor. RSC Medicinal Chemistry, 11(9), pp. 1032-1040. Royal Society of Chemistry 10.1039/D0MD00145G

Vermij, Sarah H.; Rougier, Jean-Sébastien; Agulló-Pascual, Esperanza; Rothenberg, Eli; Delmar, Mario; Abriel, Hugues (2020). Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circulation. Arrhythmia and electrophysiology, 13(7), pp. 628-639. Lippincott Williams & Wilkins 10.1161/CIRCEP.119.008241

Stoklosa, Paulina; Probst, Daniel; Reymond, Jean-Louis; Peinelt, Christine (2020). The name tells the story: Two-pore channels. Cell calcium, 89, p. 102215. Elsevier 10.1016/j.ceca.2020.102215

Kallol, Sampada; Albrecht, Christiane (2020). Materno-fetal cholesterol transport during pregnancy. Biochemical Society transactions, 48(3), pp. 775-786. Portland Press 10.1042/BST20190129

Poirier, Marion; Pujol-Giménez, Jonai; Manatschal, Cristina; Bühlmann, Sven; Embaby, Ahmed; Javor, Sacha; Hediger, Matthias A.; Reymond, Jean-Louis (2020). Pyrazolyl-pyrimidones inhibit the function of human solute carrier protein SLC11A2 (hDMT1) by metal chelation. RSC Medicinal Chemistry, 11(9), pp. 1023-1031. Royal Society of Chemistry 10.1039/D0MD00085J

Zaugg, Jonas; Melhem, Hassan; Huang, Xiao; Wegner, Malgorzata; Baumann, Marc; Surbek, Daniel; Körner, Meike; Albrecht, Christiane (2020). Gestational diabetes mellitus affects placental iron homeostasis: Mechanism and clinical implications. FASEB journal, 34(6), pp. 7311-7329. Federation of American Societies for Experimental Biology 10.1096/fj.201903054R

Dawoody Nejad, Ladan; Stumpe, Michael; Rauch, Monika; Hemphill, Andrew; Schneiter, Roger; Bütikofer, Peter; Serricchio, Mauro (2020). Mitochondrial sphingosine-1-phosphate lyase is essential for phosphatidylethanolamine synthesis and survival of Trypanosoma brucei. Scientific reports, 10(1), p. 8268. Springer Nature 10.1038/s41598-020-65248-x

Drożdżyk, Katarzyna; Sawicka, Marta; Bahamonde-Santos, Maria-Isabel; Zaugg, Jonas; Deneka, Dawid; Albrecht, Christiane; Dutzler, Raimund (2020). Cryo-EM structures and functional properties of CALHM channels of the human placenta. eLife, 9 eLife Sciences Publications 10.7554/eLife.55853

Maguy, Ange; Kucera, Jan; Wepfer, Jonas P.; Forest, Virginie; Charpentier, Flavien; Li, Jin (2020). KCNQ1 Antibodies for Immunotherapy of Long QT Syndrome Type 2. Journal of the American College of Cardiology, 75(17), pp. 2140-2152. Elsevier 10.1016/j.jacc.2020.02.067

Skalicka-Wozniak, Krystyna; Gertsch, Jürg (2020). Antipsychotic natural products. In: Annual Reports in Medicinal Chemistry 55 (pp. 481-515). Elsevier 10.1016/bs.armc.2020.03.004

Kappel, Sven; Kilch, Tatiana; Baur, Roland; Lochner, Martin; Peinelt, Christine (2020). The Number and Position of Orai3 Units within Heteromeric Store-Operated Ca2+ Channels Alter the Pharmacology of ICRAC. International journal of molecular sciences, 21(7) MDPI 10.3390/ijms21072458

Petrelli, Francesco; Dallérac, Glenn; Pucci, Luca; Calì, Corrado; Zehnder, Tamara; Sultan, Sébastien; Lecca, Salvatore; Chicca, Andrea; Ivanov, Andrei; Asensio, Cédric S; Gundersen, Vidar; Toni, Nicolas; Knott, Graham William; Magara, Fulvio; Gertsch, Jürg; Kirchhoff, Frank; Déglon, Nicole; Giros, Bruno; Edwards, Robert H; Mothet, Jean-Pierre; ... (2020). Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments. Molecular psychiatry, 25(4), pp. 732-749. Nature Publishing Group 10.1038/s41380-018-0226-y

Saliakoura, Maria; Reynoso-Moreno, Inés; Pozzato, Chiara; Rossi Sebastiano, Matteo; Galié, Mirco; Gertsch, Jürg; Konstantinidou, Georgia (2020). The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Oncogene, 39(14), pp. 2948-2960. Springer Nature 10.1038/s41388-020-1196-5

Gyimesi, Gergely; Albano, Giuseppe; Fuster, Daniel G.; Hediger, Matthias A.; Pujol-Giménez, Jonai (2020). Correction: Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2). Journal of biological chemistry, 295(13), p. 4369. American Society for Biochemistry and Molecular Biology 10.1074/jbc.AAC120.013245

Fuenzalida, Bárbara; Cantin, Claudette; Kallol, Sampada; Carvajal, Lorena; Pastén, Valentina; Contreras-Duarte, Susana; Albrecht, Christiane; Gutierrez, Jaime; Leiva, Andrea (2020). Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia. Scientific Reports, 10(1), p. 5264. Nature Publishing Group 10.1038/s41598-020-61629-4

Ross-Kaschitza, Daniela; Altmann, Michael (2020). eIF4E and Interactors from Unicellular Eukaryotes. International journal of molecular sciences, 21(6) MDPI 10.3390/ijms21062170

Bhardwaj, Rajesh; Augustynek, Bartlomiej S.; Ercan-Herbst, Ebru; Kandasamy, Palanivel; Seedorf, Matthias; Peinelt, Christine; Hediger, Matthias A. (2020). Ca2+/Calmodulin Binding to STIM1 Hydrophobic Residues Facilitates Slow Ca2+-Dependent Inactivation of the Orai1 Channel. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 54(2), pp. 252-270. 10.33594/000000218

Stoklosa, Paulina; Borgström, Anna; Kappel, Sven; Peinelt, Christine (2020). TRP Channels in Digestive Tract Cancers. International journal of molecular sciences, 21(5) MDPI 10.3390/ijms21051877

Hirschi, Stephan; Kalbermatter, David; Ucurum, Zöhre; Fotiadis, Dimitrios (2020). Cryo-electron microscopic and X-ray crystallographic analysis of the light-driven proton pump proteorhodopsin reveals a pentameric assembly. Journal of structural biology: X, 4(100024), p. 100024. Elsevier 10.1016/j.yjsbx.2020.100024

Vermij, S.H.; Abriel, H.; Kucera, J.P. (2020). A fundamental evaluation of the electrical properties and function of cardiac transverse tubules. Biochimica et biophysica acta - molecular cell research, 1867(3), p. 118502. Elsevier 10.1016/j.bbamcr.2019.06.016

Amarouch, Mohamed-Yassine; Kurt, Han; Delemotte, Lucie; Abriel, Hugues (2020). Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Nav1.5. Molecules, 25(4), p. 902. MDPI 10.3390/molecules25040902

Bonetti, Sara; Hirschi, Stephan; Bosshart, Patrick D. (2020). Expression, purification and crystallization of an SLC16 monocarboxylate transporter family homologue specific for l-lactate. Protein expression and purification, 165, p. 105484. Elsevier 10.1016/j.pep.2019.105484

Gado, Francesca; Arena, Chiara; Fauci, Cristiana La; Reynoso-Moreno, Ines; Bertini, Simone; Digiacomo, Maria; Meini, Serena; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano; Gertsch, Jürg; Chicca, Andrea; Manera, Clementina (2020). Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system. Bioorganic chemistry, 94, p. 103353. Elsevier 10.1016/j.bioorg.2019.103353

Maguy, Ange; Tardif, Jean-Claude; Busseuil, David; Ribi, Camillo; Li, Jin (2020). Autoantibody Signature in Cardiac Arrest. Circulation, 141(22), pp. 1764-1774. American Heart Association 10.1161/CIRCULATIONAHA.119.044408

Hirschi, Stephan; Fotiadis, Dimitrios (2020). Purification of Membrane Proteins by Affinity Chromatography with On-Column Protease Cleavage. In: Perez, Camilo; Maier, Timm (eds.) Expression, Purification, and Structural Biology of Membrane Proteins. Methods in Molecular Biology: Vol. 2127 (pp. 139-150). Humana Press/Springer 10.1007/978-1-0716-0373-4_10

Picca, Giovanni; Probst, Markus; Langenegger, Simon M.; Khorev, Oleg; Bütikofer, Peter; Menon, Anant K; Häner, Robert (2020). Nonenzymatic synthesis of anomerically pure, mannosyl-based molecular probes for scramblase identification studies. Beilstein journal of organic chemistry, 16, pp. 1732-1739. Beilstein-Institut 10.3762/bjoc.16.145

Kalbermatter, David; Shrestha, Neeta; Gall, Flavio M.; Wyss, Marianne; Riedl, Rainer; Plattet, Philippe; Fotiadis, Dimitrios (2020). Cryo-EM structure of the prefusion state of canine distemper virus fusion protein ectodomain. Journal of structural biology: X, 4, p. 100021. Elsevier 10.1016/j.yjsbx.2020.100021

Knight, Anthony; Hemmings, Jennifer L.; Winfield, Ian; Leuenberger, Michele; Frattini, Eugenia; Frenguelli, Bruno G.; Dowell, Simon J.; Lochner, Martin; Ladds, Graham (2020). Correction to Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity. Journal of medicinal chemistry, 63(18), p. 10531. American Chemical Society 10.1021/acs.jmedchem.0c01416

Karahoda, Rona; Abad, Cilia; Horackova, Hana; Kastner, Petr; Zaugg, Jonas; Cerveny, Lukas; Kucera, Radim; Albrecht, Christiane; Staud, Frantisek (2020). Dynamics of Tryptophan Metabolic Pathways in Human Placenta and Placental-Derived Cells: Effect of Gestation Age and Trophoblast Differentiation. Frontiers in cell and developmental biology, 8, p. 574034. Frontiers 10.3389/fcell.2020.574034

Jeckelmann, Jean-Marc; Ilgü, Hüseyin; Bosshart, Patrick D.; Fotiadis, Dimitrios José (2020). A procedure and double-chambered device for macromolecular crystal flash-cooling in different cryogenic liquids. PLoS ONE, 15(9), e0239706. Public Library of Science 10.1371/journal.pone.0239706

Lemmin, Thomas; Kalbermatter, David; Harder, Daniel; Plattet, Philippe; Fotiadis, Dimitrios (2020). Structures and dynamics of the novel S1/S2 protease cleavage site loop of the SARS-CoV-2 spike glycoprotein. Journal of structural biology: X, 4, p. 100038. Elsevier 10.1016/j.yjsbx.2020.100038

Gillet, Ludovic; Guichard, Sabrina; Essers, Maria C.; Rougier, Jean-Sébastien; Abriel, Hugues (2019). Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter. Scientific reports, 9(1), p. 19422. Springer Nature 10.1038/s41598-019-55950-w

Manatschal, Cristina; Pujol-Giménez, Jonai; Poirier, Marion; Reymond, Jean-Louis; Hediger, Matthias A.; Dutzler, Raimund (2019). Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds. eLife, 8 eLife Sciences Publications 10.7554/eLife.51913

Schädeli, David Lukas; Serricchio, Mauro; Ben Hamidane, Hisham; Loffreda, Alessio; Hemphill, Andrew; Beneke, Tom; Gluenz, Eva; Graumann, Johannes; Bütikofer, Peter (2019). Cardiolipin depletion-induced changes in the Trypanosoma brucei proteome. FASEB journal, 33(12), pp. 13161-13175. Federation of American Societies for Experimental Biology 10.1096/fj.201901184RR

Neubauer, Jacqueline; Wang, Zizun; Rougier, Jean-Sébastien; Abriel, Hugues; Rieubland, Claudine; Bartholdi, Deborah; Haas, Cordula; Medeiros-Domingo, Argelia (2019). Functional characterization of a novel SCN5A variant associated with long QT syndrome and sudden cardiac death. International journal of legal medicine, 133(6), pp. 1733-1742. Springer 10.1007/s00414-019-02141-x

Kappel, Sven; Stoklosa, Paulina; Hauert, Barbara; Ross-Kaschitza, Daniela; Borgström, Anna; Baur, Roland; Galván, José A.; Zlobec, Inti; Peinelt, Christine (2019). TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells. Molecular oncology, 13(11), pp. 2393-2405. FEBS Press 10.1002/1878-0261.12566

Casini, Simona; Albesa, Maxime; Wang, Zizun; Portero, Vincent; Ross-Kaschitza, Daniela; Rougier, Jean-Sébastien; Marchal, Gerard A; Chung, Wendy K; Bezzina, Connie R; Abriel, Hugues; Remme, Carol Ann (2019). Functional Consequences of the SCN5A-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice. International journal of molecular sciences, 20(20) MDPI 10.3390/ijms20205033

Jelk, Jennifer; Balmer, Vreni; Stibal, David; Giannini, Federico; Süss-Fink, Georg; Bütikofer, Peter; Furrer, Julien; Hemphill, Andrew (2019). Anti-parasitic dinuclear thiolato-bridged arene ruthenium complexes alter the mitochondrial ultrastructure and membrane potential in Trypanosoma brucei bloodstream forms. Experimental parasitology, 205, p. 107753. Elsevier 10.1016/j.exppara.2019.107753

Kappel, Sven; Borgström, Anna; Stoklosa, Paulina; Dörr, Kathrin; Peinelt, Christine (2019). Store-operated calcium entry in disease: Beyond STIM/Orai expression levels. Seminars in cell & developmental biology, 94, pp. 66-73. Elsevier 10.1016/j.semcdb.2019.01.003

R. Cunha, Micael; Bhardwaj, Rajesh; Lindinger, Sonja; Butorac, Carmen; Romanin, Christoph; Hediger, Matthias; Reymond, Jean-Louis (2019). Photoswitchable Inhibitor of the Calcium Channel TRPV6. ACS medicinal chemistry letters, 10(9), pp. 1341-1345. American Chemical Society 10.1021/acsmedchemlett.9b00298

Leuenberger, Michele; Bernhard, Stephanie; Grossenbacher, Philipp; Stieger, Bruno; Lochner, Martin (6 September 2019). Synthesis of Fluorescent Tools to Better Understand the Canalicular Lipid Transporter System. CHIMIA, 73(7/8). Schweizerische Chemische Gesellschaft

Preti, Barbara; Leuenberger, Michele; Lochner, Martin; Frenguelli, Bruno G.; Ladds, Graham (6 September 2019). Development of Molecular Tools for the Cellular Study of Adenosine A1 Receptors. CHIMIA, 73(7/8). Schweizerische Chemische Gesellschaft

Schild, Achille; Bhardwaj, Rajesh; Hediger, Matthias; Lochner, Martin (6 September 2019). Diverse effects of halogenated 2-aminoethoxydiphenyl borate derivatives on store-operated calcium entry in breast cancer cells. CHIMIA, 73(7/8). Schweizerische Chemische Gesellschaft

Tscherrig, Dominic; Bhardwaj, Rajesh; Dernic, Jan; Hediger, Matthias; Lochner, Martin (6 September 2019). Synthesis of functionalized probes based on GSK7975A to study SOCE. CHIMIA, 73(7/8). Schweizerische Chemische Gesellschaft

Bartholomäus, Ruben; Nicolussi, Simon; Baumann, Alice; Rau, Mark; Simão, Ana Catarina; Gertsch, Jürg; Altmann, Karl-Heinz (2019). Total Synthesis of the Endocannabinoid Uptake Inhibitor Guineensine and SAR Studies. ChemMedChem, 14(17), pp. 1590-1596. Wiley-VCH 10.1002/cmdc.201900390

Albrecht, Christiane; Chamley, Larry; Charnock-Jones, D Stephen; Collins, Sally; Fujiwara, Hiroshi; Golos, Thaddeus; Grayo, Solene; Hannan, Natalie; Harris, Lynda; Ichizuka, Kiyotake; Illsley, Nicholas P; Iwashita, Mitsutoshi; Kallol, Sampada; Al-Khan, Abdulla; Lash, Gendie; Nagamatsu, Takeshi; Nakashima, Akitoshi; Niimi, Kaoru; Nomoto, Masataka; Redman, Christopher; ... (2019). IFPA meeting 2018 workshop report II: Abnormally invasive placenta; inflammation and infection; preeclampsia; gestational trophoblastic disease and drug delivery. Placenta, 84, pp. 9-13. Elsevier 10.1016/j.placenta.2019.02.006

van Opbergen, Chantal J M; Noorman, Maartje; Pfenniger, Anna; Copier, Jaël S; Vermij, Sarah H.; Li, Zhen; van der Nagel, Roel; Zhang, Mingliang; de Bakker, Jacques M T; Glass, Aaron M; Mohler, Peter J; Taffet, Steven M; Vos, Marc A; van Rijen, Harold V M; Delmar, Mario; van Veen, Toon A B (2019). Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress. International journal of molecular sciences, 20(17) MDPI 10.3390/ijms20174076

Pereira, Gustavo José Vasco; Tavares, Maurício Temotheo; Azevedo, Ricardo Alexandre; Martins, Barbara Behr; Rodrigues Cunha, Micael; Bhardwaj, Rajesh; Cury, Yara; Zambelli, Vanessa Olzon; Barbosa, Euzébio Guimarães; Hediger, Matthias A.; Parise-Filho, Roberto (2019). Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling. Bioorganic & medicinal chemistry, 27(13), pp. 2893-2904. Elsevier 10.1016/j.bmc.2019.05.020

El Mokh, Oussama; Taelmann, Vincent; Radojewski, Piotr; Rölli, Matthias Andreas; Stooss, Amandine; Dumont, Rebecca A; Dettmer, Matthias; Phillips, Wayne; Walter, Martin Alexander; Charles, Roch-Philippe (2019). MEK inhibition induces therapeutic iodine uptake in a murine model of anaplastic thyroid cancer. Journal of nuclear medicine, 60(7), pp. 917-923. Society of Nuclear Medicine 10.2967/jnumed.118.216721

Schürch, Christian M; Rölli, Matthias A.; Forster, Stefan; Wasmer, Marie-Hélène; Brühl, Frido; Maire, Renaud S.; Di Pancrazio, Sergio; Ruepp, Marc-David; Giger, Roland; Perren, Aurel; Schmitt, Anja M.; Krebs, Philippe; Charles, Roch-Philippe; Dettmer, Matthias S. (2019). Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy. Thyroid, 29(7), pp. 979-992. Mary Ann Liebert 10.1089/thy.2018.0555

Beswick, Paul; Wahab, Ben; Honey, Mark A.; Paradowski, Michael; Ke, Jiang; Lochner, Martin; Murrell-Lagnado, Ruth D.; Thompson, Andrew J. (2019). A challenge finding P2X1 and P2X4 ligands. Neuropharmacology, 157(107674), p. 107674. Elsevier 10.1016/j.neuropharm.2019.107674

Bosshart, Patrick D.; Kalbermatter, David; Bonetti, Sara; Fotiadis, Dimitrios (2019). Mechanistic basis of L-lactate transport in the SLC16 solute carrier family. Nature communications, 10(1), p. 2649. Nature Publishing Group 10.1038/s41467-019-10566-6

Salm, Andrea; Gertsch, Jürg (2019). Cultural perception of triatomine bugs and Chagas disease in Bolivia: a cross-sectional field study. Parasites & Vectors, 12(1), p. 291. BioMed Central 10.1186/s13071-019-3546-0

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Fotiadis, Dimitrios; Jeckelmann, Jean-Marc (2019). The structure of the human 4F2hc-LAT1 heteromeric amino acid transporter. Science China. Life sciences, 62(6), pp. 848-850. Springer 10.1007/s11427-019-9558-5

Marino, Silvia; de Ridder, Daniëlle; Bishop, Ryan T; Renema, Nathalie; Ponzetti, Marco; Sophocleous, Antonia; Capulli, Mattia; Aljeffery, Abdullah; Carrasco, Giovana; Dalghi Gens, Marianela; Khogeer, Asim; Ralston, Stuart H; Gertsch, Jürg; Lamoureux, Francois; Heymann, Dominique; Rucci, Nadia; Idris, Aymen I (2019). Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice. EBioMedicine, 44, pp. 452-466. Elsevier 10.1016/j.ebiom.2019.05.048

Häfliger, Pascal; Charles, Roch-Philippe (2019). The L-Type Amino Acid Transporter LAT1-An Emerging Target in Cancer. International journal of molecular sciences, 20(10) MDPI 10.3390/ijms20102428

Gertsch, Jürg (2019). Scaffold and organism hopping with chemical probes. Nature chemical biology, 15(5), pp. 428-429. Springer Nature 10.1038/s41589-019-0275-9

Butorac, Carmen; Muik, Martin; Derler, Isabella; Stadlbauer, Michael; Lunz, Victoria; Krizova, Adéla; Lindinger, Sonja; Schober, Romana; Frischauf, Irene; Bhardwaj, Rajesh; Hediger, Matthias A.; Groschner, Klaus; Romanin, Christoph (2019). A novel STIM1-Orai1 gating interface essential for CRAC channel activation. Cell calcium, 79, pp. 57-67. Elsevier 10.1016/j.ceca.2019.02.009

Lu, Huixin; Mazumder, Mostafizur; Jaikaran, Anna S I; Kumar, Anil; Leis, Eric K; Xu, Xiuling; Altmann, Michael; Cochrane, Alan; Woolley, G Andrew (2019). A Yeast System for Discovering Optogenetic Inhibitors of Eukaryotic Translation Initiation. ACS synthetic biology, 8(4), pp. 744-757. American Chemical Society 10.1021/acssynbio.8b00386

Melhem, Hassan; Kallol, Sampada; Huang, Xiao; Lüthi, Michael; Ontsouka, Edgar; Keogh, Adrian; Stroka, Deborah; Thormann, Wolfgang; Schneider, Henning; Albrecht, Christiane (2019). Placental secretion of apolipoprotein A1 and E: the anti-atherogenic impact of the placenta. Scientific Reports, 9(1), p. 6225. Nature Publishing Group 10.1038/s41598-019-42522-1

Gaitzsch, Jens; Hirschi, Stephan; Freimann, Sven; Fotiadis, Dimitrios; Meier, Wolfgang (2019). Directed Insertion of Light-Activated Proteorhodopsin into Asymmetric Polymersomes from an ABC Block Copolymer. Nano letters, 19(4), pp. 2503-2508. American Chemical Society 10.1021/acs.nanolett.9b00161

Stergachis, Andrew B; Pujol Gimenez, Jonai; Gyimesi, Gergely; Fuster, Daniel Guido; Albano, Giuseppe; Troxler, Marina; Picker, Jonathan; Rosenberg, Paul A; Bergin, Ann; Peters, Jurriaan; Moufawad El Achkar, Christelle; Harini, Chellamani; Manzi, Shannon; Rotenberg, Alexander; Hediger, Matthias A.; Rodan, Lance H (2019). Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism. Annals of neurology, 85(6), pp. 921-926. Wiley-Blackwell 10.1002/ana.25477

Dornbierer, Dario A; Kometer, Michael; Von Rotz, Robin; Studerus, Erich; Gertsch, Jürg; Gachet Otanez, M. Salomé; Vollenweider, Franz X; Seifritz, Erich; Bosch, Oliver G; Quednow, Boris B (2019). Effects of gamma-hydroxybutyrate on neurophysiological correlates of performance and conflict monitoring. European neuropsychopharmacology, 29(4), pp. 539-548. Elsevier 10.1016/j.euroneuro.2019.02.004

Gyimesi, Gergely; Albano, Giuseppe; Fuster, Daniel Guido; Hediger, Matthias A; Pujol Gimenez, Jonai (2019). Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2). Journal of biological chemistry, 294(20), pp. 8046-8063. American Society for Biochemistry and Molecular Biology 10.1074/jbc.RA118.006113

Delalande, Clémence; Awale, Mahendra; Rubin, Matthias; Probst, Daniel; Ozhathil, Lijo C.; Gertsch, Jürg; Abriel, Hugues; Reymond, Jean-Louis (2019). Optimizing TRPM4 inhibitors in the MHFP6 chemical space. European journal of medicinal chemistry, 166, pp. 167-177. Elsevier 10.1016/j.ejmech.2019.01.048

Borgström, A.; Kiener, M.; Kappel, S.; Hauert, B.; Delalande, C.; Zoni, E.; Reymond, J.; Thalmann, G. N.; Peinelt, C.; Kruithof-de Julio, M. (15 March 2019). Investigation of TRPM4 and store-operated calcium entry in prostate cancer cell systems and a primary prostate cancer stem cell model. European Urology Supplements, 18(1), e342-e342. Elsevier https://doi.org/10.1016/S1569-9056(19)30254-4

Gaugaz, Fabienne Zdenka; Chicca, Andrea; Redondo-Horcajo, Mariano; Barasoain, Isabel; Díaz, J Fernando; Altmann, Karl-Heinz (2019). Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate. International journal of molecular sciences, 20(5) MDPI 10.3390/ijms20051113

Granchi, Carlotta; Lapillo, Margherita; Glasmacher, Sandra; Bononi, Giulia; Licari, Cristina; Poli, Giulio; El Boustani, Maguie; Caligiuri, Isabella; Rizzolio, Flavio; Gertsch, Jürg; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea (2019). Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor. Journal of medicinal chemistry, 62(4), pp. 1932-1958. American Chemical Society 10.1021/acs.jmedchem.8b01483

Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2019). Volta Phase Plate Cryo-EM Structure of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2. International journal of molecular sciences, 20(4) MDPI 10.3390/ijms20040931

Hirschi, Stephan; Fischer, Nathalie; Kalbermatter, David; Laskowski, P R; Ucurum, Zöhre; Müller, D J; Fotiadis, Dimitrios (2019). Design and assembly of a chemically switchable and fluorescently traceable light-driven proton pump system for bionanotechnological applications. Scientific reports, 9(1), p. 1046. Springer Nature 10.1038/s41598-018-37260-9

Kalbermatter, David; Shrestha, Neeta; Ebert, Nadine; Herren, Michael; Moll, Pascal Dominique; Plemper, Richard K; Altmann, Karl-Heinz; Langedijk, Johannes P; Gall, Flavio; Lindenmann, Urs; Riedl, Rainer; Fotiadis, Dimitrios José; Plattet, Philippe (2019). Primary resistance mechanism of the canine distemper virus fusion protein against a small-molecule membrane fusion inhibitor. Virus research, 259, pp. 28-37. Elsevier 10.1016/j.virusres.2018.10.003

Dhayat, Nasser A.; Lüthi, David; Schneider, Lisa; Mattmann, Cedric; Vogt, Bruno; Fuster, Daniel Guido (2019). Dinstinct phenotype of kidney stone formers with renal phosphate leak. Nephrology, dialysis, transplantation, 34(1), pp. 129-137. Oxford University Press 10.1093/ndt/gfy170

Bulla, M.; Gyimesi, Gergely; Kim, JH.; Bhardwaj, Rajesh; Hediger, Matthias; Frieden, M.; Demaurex, N. (2019). ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain. Journal of physiology, 597(2), pp. 561-582. Wiley-Blackwell 10.1113/JP277079

Jack, Thomas; Leuenberger, Michele; Ruepp, Marc-David; Vernekar, Sanjeev Kumar V; Thompson, Andrew James; Braga-Lagache, Sophie; Heller, Manfred; Lochner, Martin (2019). Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-crosslinking Antagonists. ACS chemical neuroscience, 10(1), pp. 438-450. American Chemical Society 10.1021/acschemneuro.8b00327

Marionneau, Céline; Abriel, Hugues (2019). Cardiac Sodium Current Under Sympathetic Control: Protein Phosphatase 2A Regulates Cardiac Na+ Channels. Circulation research, 124(5), pp. 674-676. Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.119.314680

Rougier, Jean-Sébastien; Essers, Maria Cristina; Gillet, Ludovic; Guichard, Sabrina Lucienne Anny; Sonntag, Stephan; Shmerling, Doron; Abriel, Hugues (2019). A Distinct Pool of Nav1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Frontiers in physiology, 10(834), p. 834. Frontiers Research Foundation 10.3389/fphys.2019.00834

Lüscher, Benjamin; Surbek, Daniel; Clemençon, Benjamin; Huang, Xiao; Albrecht, Christiane; Marini, Camilla; Hediger, Matthias; Baumann, Marc (2019). Different Pharmacological Properties of GLUT9a and GLUT9b: Potential Implications in Preeclampsia. Cellular physiology and biochemistry, 53(3), pp. 508-517. Cell Physiol Biochem Press 10.33594/000000154

Bosshart, Patrick; Fotiadis, Dimitrios (2019). Secondary Active Transporters. Sub-cellular biochemistry, 92, pp. 275-299. Springer 10.1007/978-3-030-18768-2_9

Jeckelmann, Jean-Marc; Erni, Bernhard (2019). Carbohydrate Transport by Group Translocation: The Bacterial Phosphoenolpyruvate: Sugar Phosphotransferase System. In: Kuhn, Andreas (ed.) Bacterial Cell Walls and Membranes. Subcellular Biochemistry: Vol. 92 (pp. 223-274). Boston: Springer 10.1007/978-3-030-18768-2_8

Vermij, Sarah Helena; Abriel, Hugues; Kucera, Jan (2019). Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules. Frontiers in physiology, 10(1487) Frontiers Research Foundation 10.3389/fphys.2019.01487

Bosshart, Patrick; Kalbermatter, David; Bonetti, Sara; Fotiadis, Dimitrios (2019). Structure and function of a monocarboxylate transporter homolog specific for L-lactate. Molecular & cellular oncology, 6(6), e1646605. Taylor & Francis 10.1080/23723556.2019.1646605

Borgström, A.; Kiener, M.; Kappel, S.; Hauert, B.; Delalande, C.; Zoni, E.; Reymond, J.-L.; Thalmann, G. N.; Peinelt, C.; Kruithof-de Julio, M. (2019). Investigation of TRPM4 and store-operated calcium entry in prostate cancer cell systems and a primary prostate cancer stem cell model. Der Urologe, 58(Suppl 1), S42-S42. Springer https://doi.org/10.1007/s00120-019-1018-y

Grafinger, Katharina Elisabeth; Mandhair, Harpreet Kaur; Broillet, Alain; Gertsch, Jürg; Weinmann, Wolfgang (2019). Cytotoxicity of the synthetic cannabinoids 5C-AKB48, 5F-MDMB-PINACA, ADB-CHMINACA, MDMB-CHMICA and NM-2201 in A549 and TR146 cell lines. Forensic toxicology, 37(2), pp. 398-411. Springer 10.1007/s11419-019-00474-1

Poirier, Marion; Awale, Mahendra; Rölli, Matthias A.; Giuffredi, Guy T.; Ruddigkeit, Lars; Evensen, Lasse; Stooss, Amandine; Calarco, Serafina; Lorens, James B.; Charles, Roch-Philippe; Reymond, Jean-Louis (2018). Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT-β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2. ChemMedChem, 14(2), pp. 224-236. Wiley-VCH 10.1002/cmdc.201800554

Tamò, Luca; Hibaoui, Youssef; Kallol, Sampada; Alves, Marco; Albrecht, Christiane; Hostettler, Katrin E; Feki, Anis; Rougier, Jean-Sébastien; Abriel, Hugues; Knudsen, Lars; Gazdhar, Amiq; Geiser, Thomas (2018). Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. American journal of physiology - lung cellular and molecular physiology, 315(6), L921-L932. American Physiological Society 10.1152/ajplung.00357.2017

Schröck, Alexandra; Henzi, Anna; Bütikofer, Peter; König, Stefan; Weinmann, Wolfgang (2018). Determination of the formation rate of phosphatidylethanol by phospholipase D (PLD) in blood and test of two selective PLD inhibitors. Alcohol, 73, pp. 1-7. Elsevier 10.1016/j.alcohol.2018.03.003

Kallol, Sampada Arvindrao; Moser-Haessig, Ruedi; Ontsouka, Edgar; Albrecht, Christiane (2018). Comparative expression patterns of selected membrane transporters in differentiated BeWo and human primary trophoblast cells. Placenta, 72-73, pp. 48-52. Elsevier 10.1016/j.placenta.2018.10.008

Wang, Lei; Iwasaki, Yugo; Andra, Kiran K; Pandey, Kalpana; Menon, Anant K; Bütikofer, Peter (2018). Scrambling of natural and fluorescently tagged phosphatidylinositol by reconstituted G protein-coupled receptor and TMEM16 scramblases. Journal of biological chemistry, 293(47), pp. 18318-18327. American Society for Biochemistry and Molecular Biology 10.1074/jbc.RA118.004213

Chevalier, Morgan Yoann Edwin; Vermij, Sarah Helena; Wyler, Kurt; Gillet, Ludovic; Keller, Irene; Abriel, Hugues (2018). Corrigendum: Transcriptomic analyses of murine ventricular cardiomyocytes. Scientific data, 5(180216), p. 180216. Nature Publishing Group 10.1038/sdata.2018.216

Kandasamy, Palanivel; Gyimesi, Gergely; Kanai, Yoshikatsu; Hediger, Matthias (2018). Amino acid transporters revisited: New views in health and disease. Trends in biochemical sciences, 43(10), pp. 752-789. Elsevier Current Trends 10.1016/j.tibs.2018.05.003

Chicca, Andrea; Schafroth, M A; Reynoso, Ines del Carmen; Erni, R; Petrucci, Vanessa; Carreira, E M; Gertsch, Jürg (2018). Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high. Science Advances, 4(10), eaat2166. American Association for the Advancement of Science 10.1126/sciadv.aat2166

van der Heyden, Marcel A G; Delisle, Brian P; Abriel, Hugues (2018). Editorial: Ion Channel Trafficking and Cardiac Arrhythmias. Frontiers in physiology, 9, p. 1254. Frontiers Research Foundation 10.3389/fphys.2018.01254

Häfliger, Pascal; Graff, Julien; Rubin, Matthias; Stooss, Amandine; Dettmer, Matthias S.; Altmann, Karl-Heinz; Gertsch, Jürg; Charles, Roch-Philippe (2018). The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model. Journal of experimental & clinical cancer research, 37(1), p. 234. BioMed Central 10.1186/s13046-018-0907-z

Lochner, Martin; Leuenberger, Michele; Preti, Barbara; Tesfazghi, Bereket; Bartlome, Pascal; Frenguelli, Bruno G.; Barkan-Bulman, Kerry; Ladds, Graham (10 September 2018). Development of Molecular Tools for the Study of Adenosine A1 Receptors (Unpublished). In: 7th RSC/SCI Symposium on GPCRs in Medicinal Chemistry. Verona. 10.-12.09.2018.

Preti, Barbara; Tesfazghi, Bereket; Bartlome, Pascal; Leuenberger, Michele; Frenguelli, Bruno G.; Ladds, Graham; Lochner, Martin (7 September 2018). Molecular Tools for the Cellular Study of Adenosine A1 Receptors. CHIMIA, 72(7/8). Schweizerische Chemische Gesellschaft

Schild, Achille; Bhardwaj, Rajesh; Hediger, Matthias; Lochner, Martin (7 September 2018). Study of 2-Aminoethoxy Borate (2-APB) Analogues in MDA-MB-231 and MCF-7 Cells towards Orai Isoform-specific Modulation of Store-operated Calcium Entry (SOCE). CHIMIA, 72(7/8). Schweizerische Chemische Gesellschaft

Tscherrig, Dominic; Bhardwaj, Rajesh; Hediger, Matthias; Lochner, Martin (7 September 2018). Synthesis of Functionalised Probes Based on GSK7975A to Study SOCE. CHIMIA, 72(7/8). Schweizerische Chemische Gesellschaft

Bononi, Giulia; Granchi, Carlotta; Lapillo, Margherita; Giannotti, Massimiliano; Nieri, Daniela; Fortunato, Serena; Boustani, Maguie El; Caligiuri, Isabella; Poli, Giulio; Carlson, Kathryn E; Kim, Sung Hoon; Macchia, Marco; Martinelli, Adriano; Rizzolio, Flavio; Chicca, Andrea; Katzenellenbogen, John A; Minutolo, Filippo; Tuccinardi, Tiziano (2018). Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors. European journal of medicinal chemistry, 157, pp. 817-836. Elsevier Masson SAS 10.1016/j.ejmech.2018.08.038

Chien, Huan-Chieh; Colas, Claire; Finke, Karissa; Springer, Seth; Stoner, Laura; Zur, Arik A; Venteicher, Brooklynn; Campbell, Jerome; Hall, Colton; Flint, Andrew; Augustyn, Evan; Hernandez, Christopher; Heeren, Nathan; Hansen, Logan; Anthony, Abby; Bauer, Justine; Fotiadis, Dimitrios José; Schlessinger, Avner; Giacomini, Kathleen M and Thomas, Allen A (2018). Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). Journal of medicinal chemistry, 61(16), pp. 7358-7373. American Chemical Society 10.1021/acs.jmedchem.8b01007

Kallol, Sampada Arvindrao; Huang, Xiao; Müller, Stefan Jürg; Ontsouka, Edgar; Albrecht, Christiane (2018). Novel Insights into Concepts and Directionality of Maternal⁻Fetal Cholesterol Transfer across the Human Placenta. International journal of molecular sciences, 19(8) MDPI 10.3390/ijms19082334

Zákány, Nóra; Oláh, Attila; Markovics, Arnold; Takács, Erika; Aranyász, Andrea; Nicolussi, Simon; Piscitelli, Fabiana; Allarà, Marco; Pór, Ágnes; Kovács, Ilona; Zouboulis, Christos C; Gertsch, Jürg; Di Marzo, Vincenzo; Bíró, Tamás; Szabó, Tamás (2018). Endocannabinoid Tone Regulates Human Sebocyte Biology. Journal of Investigative Dermatology, 138(8), pp. 1699-1706. Nature Publishing 10.1016/j.jid.2018.02.022

Bianchi, Beatrice; Smith, Paul A; Abriel, Hugues (2018). The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. Molecular brain, 11(1), p. 41. BioMed Central 10.1186/s13041-018-0385-4

Franz, Marie-Christine; Pujol Gimenez, Jonai; Montalbetti, Nicolas; Fernandez Tenorio, Miguel; DeGrado, Timothy R.; Niggli, Ernst; Romero, Michael F.; Hediger, Matthias (2018). Reassessment of the transport mechanism of the human zinc transporter SLC39A2. Biochemistry, 57(26), pp. 3976-3986. American Chemical Society 10.1021/acs.biochem.8b00511

Sigel, Erwin (2018). Key receptor involved in neuronal signalling visualized. Nature, 559(7712), pp. 37-38. Springer Nature 10.1038/d41586-018-05538-7

Sigel, Erwin; Ernst, Margot (2018). The Benzodiazepine Binding Sites of GABA Receptors. Trends in Pharmacological Sciences, 39(7), pp. 659-671. Elsevier 10.1016/j.tips.2018.03.006

Chicca, Andrea; Arena, Chiara; Bertini, Simone; Gado, Francesca; Ciaglia, Elena; Abate, Mario; Digiacomo, Maria; Lapillo, Margherita; Poli, Giulio; Bifulco, Maurizio; Macchia, Marco; Tuccinardi, Tiziano; Gertsch, Jürg; Manera, Clementina (2018). Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system. European journal of medicinal chemistry, 154, pp. 155-171. Elsevier 10.1016/j.ejmech.2018.05.019

Ozhathil, Lijo Cherian; Delalande, Clémence Marie Sandrine; Bianchi, Beatrice; Nemeth, Gabor; Kappel, Sven; Thomet, Urs; Ross, Daniela; Simonin, Céline; Rubin, Matthias; Gertsch, Jürg; Lochner, Martin; Peinelt, Christine; Reymond, Jean-Louis; Abriel, Hugues (2018). Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. British journal of pharmacology, 175(12), pp. 2504-2519. Wiley-Blackwell 10.1111/bph.14220

Benabdelaziz, Imane; Gómez-Ruiz, Santiago; Benkhaled, Mohammed; Carralero, Sandra; Schenker, Patricia; Salm, Andrea Alejandra; Gertsch, Jürg; Haba, Hamada (2018). New cycloartane-type ester triterpenes from Euphorbia pterococca and biological evaluation. Fitoterapia, 127, pp. 271-278. Elsevier Science 10.1016/j.fitote.2018.02.027

Neubauer, Jacqueline; Rougier, Jean-Sébastien; Abriel, Hugues; Haas, Cordula (2018). Functional implications of a rare variant in the sodium channel β1B subunit () in a 5-month-old male sudden infant death syndrome case. HeartRhythm Case Reports, 4(5), pp. 187-190. Elsevier 10.1016/j.hrcr.2018.01.010

Arndt, Nick; Ross-Kaschitza, Daniela; Kojukhov, Artyom; Komar, Anton A.; Altmann, Michael (2018). Properties of the ternary complex formed by yeast eIF4E, p20 and mRNA. Scientific Reports, 8(1), p. 6707. Nature Publishing Group 10.1038/s41598-018-25273-3

Schroeder, Mariana; Jakovcevski, Mira; Polacheck, Tamar; Drori, Yonat; Luoni, Alessia; Röh, Simone; Zaugg, Jonas; Ben-Dor, Shifra; Albrecht, Christiane; Chen, Alon (2018). Placental miR-340 mediates vulnerability to activity based anorexia in mice. Nature communications, 9(1), p. 1596. Nature Publishing Group 10.1038/s41467-018-03836-2

Dawoody Nejad, Ladan; Serricchio, Mauro; Jelk, Jennifer; Hemphill, Andrew; Bütikofer, Peter (2018). TbLpn, a key enzyme in lipid droplet formation and phospholipid metabolism, is essential for mitochondrial integrity and growth of Trypanosoma brucei. Molecular microbiology, 109(1), pp. 105-120. Wiley 10.1111/mmi.13976

Serricchio, Mauro; Vissa, Adriano; Kim, Peter K; Yip, Christopher M; McQuibban, G Angus (2018). Cardiolipin synthesizing enzymes form a complex that interacts with cardiolipin-dependent membrane organizing proteins. Biochimica and biophysica acta - molecular and cell biology of lipids, 1863(4), pp. 447-457. Elsevier 10.1016/j.bbalip.2018.01.007

Clemençon, Benjamin; Lüscher, Benjamin; Hediger, Matthias (2018). Establishment of a novel microscale thermophoresis ligand-binding assay for characterization of SLC solute carriers using oligopeptide transporter PepT1 (SLC15 family) as a model system. Journal of pharmacological and toxicological methods, 92, pp. 67-76. Elsevier 10.1016/j.vascn.2018.03.004

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Colas, Claire; Ucurum Fotiadis, Zöhre; Schlessinger, Avner; Fotiadis, Dimitrios José (2018). Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters. International journal of molecular sciences, 19(3) MDPI 10.3390/ijms19030918

Huang, Xiao; Anderle, Pascale; Hostettler, Lu; Baumann, Marc; Surbek, Daniel; Ontsouka, Edgar; Albrecht, Christiane (2018). Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia. BMC Genomics, 19(1), p. 173. BioMed Central 10.1186/s12864-018-4518-z

Schmidt, Remo S.; Pereira de Macêdo, Juan; Steinmann, Michael Eduard; González Salgado, Amaia; Bütikofer, Peter; Sigel, Erwin; Rentsch, Doris; Mäser, Pascal (2018). Transporters of Trypanosoma brucei -phylogeny, physiology, pharmacology. FEBS journal, 285(6), pp. 1012-1023. Wiley 10.1111/febs.14302

Pathare, Ganesh Tukaram; Anderegg, Manuel; Albano, Giuseppe; Lang, Florian; Fuster, Daniel Guido (2018). Elevated FGF23 Levels in Mice Lacking the Thiazide-Sensitive NaCl cotransporter (NCC). Scientific Reports, 8(1), p. 3590. Nature Publishing Group 10.1038/s41598-018-22041-1

Hichri, Echrak; Abriel, Hugues; Kucera, Jan (2018). Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc. Journal of physiology, 596(4), pp. 563-589. Wiley-Blackwell 10.1113/JP275351

Aghazadeh Tabrizi, Mojgan; Baraldi, Pier Giovanni; Baraldi, Stefania; Ruggiero, Emanuela; De Stefano, Lucia; Rizzolio, Flavio; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Chicca, Andrea; Lapillo, Margherita; Gertsch, Jürg; Manera, Clementina; Macchia, Marco; Martinelli, Adriano; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano (2018). Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors. Journal of medicinal chemistry, 61(3), pp. 1340-1354. American Chemical Society 10.1021/acs.jmedchem.7b01845

Pathare, Ganesh Tukaram; Dhayat, Nasser; Mohebbi, Nilufar; Wagner, Carsten A.; Cheval, Lydie; Neuhaus, Thomas J.; Fuster, Daniel Guido (2018). Acute regulated expression of pendrin in human urinary exosomes. Pflügers Archiv : European journal of physiology, 470(2), pp. 427-438. Springer 10.1007/s00424-017-2049-0

Varga, Zoltan V; Matyas, Csaba; Erdelyi, Katalin; Cinar, Resat; Nieri, Daniela; Chicca, Andrea; Nemeth, Balazs Tamas; Paloczi, Janos; Lajtos, Tamas; Corey, Lukas; Hasko, Gyorgy; Gao, Bin; Kunos, George; Gertsch, Jürg; Pacher, Pal (2018). Beta-caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice. British journal of pharmacology, 175(2), pp. 320-334. Wiley-Blackwell 10.1111/bph.13722

Pathare, Ganesh Tukaram; Dhayat, Nasser; Mohebbi, Nilufar; Wagner, Carsten A.; Bobulescu, Alexandru; Moe, Orson W.; Fuster, Daniel Guido (2018). Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis. Kidney international, 93(4), pp. 871-880. Elsevier 10.1016/j.kint.2017.10.018

Bianchi, Beatrice; Ozhathil, Lijo Cherian; Medeiros Domingo, Argelia; Gollob, Michael H; Abriel, Hugues (2018). Four TRPM4 Cation Channel Mutations Found in Cardiac Conduction Diseases Lead to Altered Protein Stability. Frontiers in physiology, 9, p. 177. Frontiers Research Foundation 10.3389/fphys.2018.00177

Blancard, Malorie; Debbiche, Amal; Kato, Koichi; Cardin, Christelle; Guichard, Sabrina Lucienne Anny; Gandjbakhch, Estelle; Probst, Vincent; Haissaguerre, Michel; Extramiana, Fabrice; Hocini, Mélèze; Olivier, Geoffroy; Leenhardt, Antoine; Guicheney, Pascale; Rougier, Jean-Sébastien (2018). An African loss-of-function CACNA1C variant p.T1787M associated with a risk of ventricular fibrillation. Scientific Reports, 8(1), p. 14619. Nature Publishing Group 10.1038/s41598-018-32867-4

Thoma, Johannes; Manioglu, Selen; Kalbermatter, David; Bosshart, Patrick; Fotiadis, Dimitrios José; Müller, Daniel J (2018). Protein-enriched outer membrane vesicles as a native platform for outer membrane protein studies. Communications biology, 1(23), p. 23. Springer Nature 10.1038/s42003-018-0027-5

Goers, Roland; Thoma, Johannes; Ritzmann, Noah; Di Silvestro, Alfredo; Alter, Claudio; Gunkel-Grabole, Gesine; Fotiadis, Dimitrios José; Müller, Daniel J; Meier, Wolfgang (2018). Optimized reconstitution of membrane proteins into synthetic membranes. Communications chemistry, 1(1) Springer Nature 10.1038/s42004-018-0037-8

Reynoso, Ines del Carmen; Chicca, Andrea; Flores-Soto, Mario E; Viveros-Paredes, Juan M; Gertsch, Jürg (2018). The Endocannabinoid Reuptake Inhibitor WOBE437 Is Orally Bioavailable and Exerts Indirect Polypharmacological Effects via Different Endocannabinoid Receptors. Frontiers in molecular neuroscience, 11, p. 180. Frontiers Research Foundation 10.3389/fnmol.2018.00180

Chevalier, Morgan; Vermij, Sarah H.; Wyler, Kurt; Gillet, Ludovic; Keller, Irene; Abriel, Hugues (2018). Transcriptomic analyses of murine ventricular cardiomyocytes. Scientific data, 5(180170), p. 180170. Nature Publishing Group 10.1038/sdata.2018.170

Steinmann, Michael E.; Schmidt, Remo S.; Pereira de Macêdo, Juan; Kunz Renggli, Christina; Bütikofer, Peter; Rentsch, Doris; Mäser, Pascal; Sigel, Erwin (2017). Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei. PLoS ONE, 12(12), pp. 1-18. Public Library of Science 10.1371/journal.pone.0188219

Bertini, Simone; Chicca, Andrea; Gado, Francesca; Arena, Chiara; Nieri, Daniela; Digiacomo, Maria; Saccomanni, Giuseppe; Zhao, Pingwei; Abood, Mary E; Macchia, Marco; Gertsch, Jürg; Manera, Clementina (2017). Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor. Bioorganic & medicinal chemistry, 25(24), pp. 6427-6434. Elsevier 10.1016/j.bmc.2017.10.015

Albrecht, Christiane; Baker, Julie C; Blundell, Cassidy; Chavez, Shawn L; Carbone, Lucia; Chamley, Larry; Hannibal, Roberta L; Illsley, Nick; Kurre, Peter; Laurent, Louise C; McKenzie, Charles; Morales-Prieto, Diana; Pantham, Priyadarshini; Paquette, Alison; Powell, Katie; Price, Nathan; Rao, Balaji M; Sadovsky, Yoel; Salomon, Carlos; Tuteja, Geetu; ... (2017). IFPA meeting 2016 workshop report I: Genomic communication, bioinformatics, trophoblast biology and transport systems. Placenta, 60 Suppl 1, S5-S9. Elsevier 10.1016/j.placenta.2017.01.103

Rölli, Matthias Andreas; Ruffieux-Daidiée, Dorothée; Stooss, Amandine; El Mokh, Oussama; Phillips, Wayne A; Dettmer, Matthias; Charles, Roch-Philippe (2017). PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors. OncoTarget, 8(61), pp. 103207-103222. Impact Journals LLC 10.18632/oncotarget.21732

Chicca, Andrea; Berg, Regina; Jessen, Henning J; Marck, Nicolas; Schmid, Fabian; Burch, Patrick; Gertsch, Jürg; Gademann, Karl (2017). Biological evaluation of pyridone alkaloids on the endocannabinoid system. Bioorganic & medicinal chemistry, 25(22), pp. 6102-6114. Elsevier 10.1016/j.bmc.2017.02.031

Wongsamitkul, Nisa; Maldifassi, Maria Constanza; Simeone, Xenia Maria Laura; Baur, Roland; Ernst, Margot; Sigel, Erwin (2017). α subunits in GABAA receptors are dispensable for GABA and diazepam action. Scientific Reports, 7(1), p. 15498. Nature Publishing Group 10.1038/s41598-017-15628-7

Gottier, Petra; Serricchio, Mauro; Vitale, Rita; Corcelli, Angela; Bütikofer, Peter (2017). Cross-species complementation of bacterial- and eukaryotic-type cardiolipin synthases. Microbial cell, 4(11), pp. 376-383. Shared Science Publishers OG 10.15698/mic2017.11.598

Reynoso, Ines del Carmen; Najar-Guerrero, Israel; Escareño, Noé; Flores-Soto, Mario Eduardo; Gertsch, Jürg; Viveros-Paredes, Juan Manuel (2017). An Endocannabinoid Uptake Inhibitor from Black Pepper Exerts Pronounced Anti-Inflammatory Effects in Mice. Journal of agricultural and food chemistry, 65(43), pp. 9435-9442. American Chemical Society 10.1021/acs.jafc.7b02979

Kappel, Sven; dos Santos Marques, Ines Joao; Zoni, Eugenio; Stoklosa, Paulina Agnieszka; Peinelt, Christine; Mercader Huber, Nadia; Kruithof-de Julio, Marianna; Borgström, Anna (2017). Store-Operated Ca2+ Entry as a Prostate Cancer Biomarker — a Riddle with Perspectives. Current Molecular Biology Reports, 3(4), pp. 208-217. Springer 10.1007/s40610-017-0072-8

Patsenker, Eleonora; Chicca, Andrea; Petrucci, Vanessa; Moghadamrad, Sheida; De Gottardi, Andrea; Hampe, Jochen; Gertsch, Jürg; Semmo, Nasser; Stickel, Felix (2017). 4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice. Journal of molecular medicine JMM, 95(10), pp. 1077-1089. Springer 10.1007/s00109-017-1556-y

Ritzmann, Noah; Thoma, Johannes; Hirschi, Stephan; Kalbermatter, David; Fotiadis, Dimitrios José; Müller, Daniel J (2017). Fusion Domains Guide the Oriented Insertion of Light-Driven Proton Pumps into Liposomes. Biophysical journal, 113(6), pp. 1181-1186. Biophysical Society 10.1016/j.bpj.2017.06.022

Dhayat, Nasser; Pathare, Ganesh Tukaram; Anderegg, Manuel; Vogt, Bruno; Fuster, Daniel Guido (2017). Incomplete dRTA in kidney stone formers: diagnostic performance of furosemide/fludrocortisone testing and non-provocative clinical parameters. Clinical journal of the American Society of Nephrology, 12(9), pp. 1507-1517. American Society of Nephrology 10.2215/CJN.01320217

Verchère, Alice; Ou, Wei-Lin; Ploier, Birgit; Morizumi, Takefumi; Goren, Michael A; Bütikofer, Peter; Ernst, Oliver P; Khelashvili, George; Menon, Anant K (2017). Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum. Scientific Reports, 7(1), p. 9522. Nature Publishing Group 10.1038/s41598-017-09835-5

Petrucci, Vanessa; Chicca, Andrea; Glasmacher, Sandra Patricia; Paloczi, Janos; Cao, Zongxian; Pacher, Pal; Gertsch, Jürg (2017). Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage. Scientific Reports, 7(1), p. 9560. Nature Publishing Group 10.1038/s41598-017-09808-8

Laskowski, Pawel R; Pfreundschuh, Moritz; Stauffer, Mirko; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). High-Resolution Imaging and Multiparametric Characterization of Native Membranes by Combining Confocal Microscopy and an Atomic Force Microscopy-Based Toolbox. ACS nano, 11(8), pp. 8292-8301. American Chemical Society 10.1021/acsnano.7b03456

Leuenberger, Michele; Bernhard, Stephanie; Stieger, Bruno; Lochner, Martin (21 August 2017). Fluorescent Bile Salt Derivatives for the Investigation of the Canalicular Lipid Transporter System. CHIMIA, 71(7/8). Schweizerische Chemische Gesellschaft

Schild, Achille; Bhardwaj, Rajesh; Hediger, Matthias; Lochner, Martin (21 August 2017). Diaryl Boronic Acid Modulate Store-operated Calcium Entry (SOCE). CHIMIA, 71(7/8). Schweizerische Chemische Gesellschaft

Tscherrig, Dominic; Bhardwaj, Rajesh; Hediger, Matthias; Lochner, Martin (21 August 2017). Synthesis of Novel Probes based on GSK7975A to study SOCE. CHIMIA, 71(7/8). Schweizerische Chemische Gesellschaft

Dalghi Gens, Marianela Gisela; Ferreira-Gomes, Mariela; Montalbetti, Nicolas; Simonin, Alexandre; Strehler, Emanuel E; Hediger, Matthias; Rossi, Juan Pablo (2017). Cortical cytoskeleton dynamics regulates plasma membrane calcium ATPase isoform-2 (PMCA2) activity. Biochimica et biophysica acta - molecular cell research, 1864(8), pp. 1413-1424. Elsevier 10.1016/j.bbamcr.2017.05.014

Pujol Gimenez, Jonai; Hediger, Matthias; Gyimesi, Gergely (2017). A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters. Scientific Reports, 7(1), p. 6194. Nature Publishing Group 10.1038/s41598-017-06446-y

Lüscher, Benjamin; Marini, Camilla; Jörger Messerli, Marianne; Huang, Xiao; Hediger, Matthias; Albrecht, Christiane; Baumann, Marc Ulrich; Surbek, Daniel (2017). Placental glucose transporter (GLUT)-1 is down-regulated in preeclampsia. Placenta, 55, pp. 94-99. Elsevier 10.1016/j.placenta.2017.04.023

Kalbermatter, David; Chiu, Po-Lin; Jeckelmann, Jean-Marc; Ucurum Fotiadis, Zöhre; Walz, Thomas; Fotiadis, Dimitrios José (2017). Electron crystallography reveals that substrate release from the PTS IIC glucose transporter is coupled to a subtle conformational change. Journal of structural biology, 199(1), pp. 39-45. Elsevier 10.1016/j.jsb.2017.05.005

von Rotz, Robin; Kometer, Michael; Dornbierer, Dario; Gertsch, Jürg; Gachet Otanez, Maria Salomé; Vollenweider, Franz X; Seifritz, Erich; Bosch, Oliver G; Quednow, Boris B (2017). Neuronal oscillations and synchronicity associated with gamma-hydroxybutyrate during resting-state in healthy male volunteers. Psychopharmacology, 234(13), pp. 1957-1968. Springer 10.1007/s00213-017-4603-z

Chicca, Andrea; Nicolussi, Simon; Bartholomäus, Ruben; Blunder, Martina; Aparisi Rey, Alejandro; Petrucci, Vanessa; Reynoso, Ines del Carmen; Viveros-Paredes, Juan Manuel; Dalghi Gens, Marianela Gisela; Lutz, Beat; Schiöth, Helgi B; Soeberdt, Michael; Abels, Christoph; Charles, Roch-Philippe; Altmann, Karl-Heinz; Gertsch, Jürg (2017). Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(25), E5006-E5015. National Academy of Sciences NAS 10.1073/pnas.1704065114

Peng, J-B; Suzuki, Y; Gyimesi, Gergely; Hediger, Matthias (2017). TRPV5 and TRPV6 calcium-selective channels. In: Ashot Kozak, Juliusz; Putney, James Jr. (eds.) Calcium Entry Channels in Non-Excitable Cells. Methods in Signal Transduction Series (pp. 241-274). CRC Press

Gertsch, Jürg (2017). Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation? British journal of pharmacology, 174(11), pp. 1464-1483. Wiley-Blackwell 10.1111/bph.13676

Nisa Hernández, Lluís; Häfliger, Pascal; Poliakova, Michaela; Giger, Roland; Francica, Paola; Aebersold, Daniel; Charles, Roch-Philippe; Zimmer, Yitzhak; Medova, Michaela (2017). PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models. Molecular cancer, 16(1), p. 93. BioMed Central 10.1186/s12943-017-0660-5

Pfreundschuh, Moritz; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). Detecting Ligand-Binding Events and Free Energy Landscape while Imaging Membrane Receptors at Subnanometer Resolution. Nano letters, 17(5), pp. 3261-3269. American Chemical Society 10.1021/acs.nanolett.7b00941

Farine, Luce; Jelk, Jennifer; Choi, Jae-Yeon; Voelker, Dennis R; Nunes, Jon; Smith, Terry K; Bütikofer, Peter (2017). Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei. Molecular microbiology, 104(3), pp. 412-427. Blackwell Science 10.1111/mmi.13637

Orekhov, Philipp; Bothe, Arne; Steinhoff, Heinz-Jürgen; Shaitan, Konstantin V; Raunser, Stefan; Fotiadis, Dimitrios José; Schlesinger, Ramona; Klare, Johann P; Engelhard, Martin (2017). Sensory Rhodopsin I and Sensory Rhodopsin II Form Trimers of Dimers in Complex with their Cognate Transducers. Photochemistry and photobiology, 93(3), pp. 796-804. Blackwell Publishing 10.1111/php.12763

Hinard, Valérie; Britan, Aurore; Schaeffer, Mathieu; Zahn-Zabal, Monique; Thomet, Urs; Rougier, Jean-Sébastien; Bairoch, Amos; Abriel, Hugues; Gaudet, Pascale (2017). Annotation of functional impact of voltage-gated sodium channel mutations. Human mutation, 38(5), pp. 485-493. Wiley-Blackwell 10.1002/humu.23191

El Mokh, Oussama; Ruffieux-Daidié, Dorothée; Rölli, Matthias Andreas; Stooss, Amandine; Phillips, Wayne A; Gertsch, Jürg; Dettmer, Matthias; Charles, Roch-Philippe (2017). Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo. OncoTarget, 8(15), pp. 24604-24620. Impact Journals LLC 10.18632/oncotarget.15599

Steinmann, Michael Eduard; Schmidt, Remo S; Bütikofer, Peter; Mäser, Pascal; Sigel, Erwin (2017). TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes. Scientific Reports, 7(1), p. 656. Nature Publishing Group 10.1038/s41598-017-00752-1

Russo-Abrahão, Thais; Koeller, Carolina Macedo; Steinmann, Michael Eduard; Silva-Rito, Stephanie; Marins-Lucena, Thaissa; Alves-Bezerra, Michele; Lima-Giarola, Naira Ligia; de-Paula, Iron Francisco; González Salgado, Amaia; Sigel, Erwin; Bütikofer, Peter; Gondim, Katia Calp; Heise, Norton; Meyer-Fernandes, José Roberto (2017). H+-dependent inorganic phosphate uptake in Trypanosoma brucei is influenced by myo-inositol transporter. Journal of bioenergetics and biomembranes, 49(2), pp. 183-194. Springer 10.1007/s10863-017-9695-y

Vermij, Sarah Helena; Abriel, Hugues; van Veen, Toon A B (2017). Refining the molecular organization of the cardiac intercalated disc. Cardiovascular research, 113(3), pp. 259-275. Oxford University Press 10.1093/cvr/cvw259

Maldifassi, Maria Constanza; Sigel, Erwin (2017). Functional sites for anesthetics in GABAA receptors. OncoTarget, 8(7), pp. 10779-10780. Impact Journals LLC 10.18632/oncotarget.14616

Lochner, Martin; Hemmings, Jennifer Luise; Leuenberger, Michele; Meyer, Jonas; Bartlome, Pascal; Perozzo, Alyssa Victoria; Frenguelli, Bruno G.; Winfield, Ian; Ladds, Graham (12 February 2017). Molecular Tools for the Cellular Study of Adenosine A1 Receptors (Unpublished). In: GDCh/SCS conference on Frontiers in Medicinal Chemistry. Bern. 12.-15.02.2017.

Leuenberger, Michele; Lochner, Martin; Bernhard, Stephanie; Stieger, Bruno (12 February 2017). Synthesis of Fluorescent Bile Salt Derivatives and Their Utility as Tracers of the Canalicular Lipid Transporter System (Unpublished). In: GDCh/SCS conference on Frontiers in Medicinal Chemistry. Bern. 12.-15.2.2017.

Ruepp, Marc-David; Wei, Hao; Leuenberger, Michele; Lochner, Martin; Thompson, Andrew James (2017). The binding orientation of structurally-related ligands can differ; A cautionary note. Neuropharmacology, 119, pp. 48-61. Elsevier 10.1016/j.neuropharm.2017.01.023

Gachet Otanez, Maria Salomé; Schubert, Alexandra; Calarco, Serafina; Boccard, Julien; Gertsch, Jürg (2017). Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom. Scientific Reports, 7, p. 41177. Nature Publishing Group 10.1038/srep41177

Thompson, Andrew J.; Metzger, Simon; Lochner, Martin; Ruepp, Marc-David (2017). The binding orientation of epibatidine at α7 nACh receptors. Neuropharmacology, 116, pp. 421-428. Elsevier 10.1016/j.neuropharm.2017.01.008

Ontsouka, Edgar; Huang, Xiao; Aliyev, Eldar; Albrecht, Christiane (2017). In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland. Molecular and cellular endocrinology, 439, pp. 35-45. Elsevier Ireland 10.1016/j.mce.2016.10.016

Mathieu, Christoph; Pereira de Macêdo, Juan; Hürlimann, Daniel; Wirdnam, Corina; Haindrich, Alexander; Suter, Marianne; González Salgado, Amaia; Schmidt, Remo; Inbar, Ehud; Mäser, Pascal; Bütikofer, Peter; Zilberstein, Dan; Rentsch, Doris (2017). Arginine and Lysine Transporters Are Essential for Trypanosoma brucei. PLoS ONE, 12(1), e0168775. Public Library of Science 10.1371/journal.pone.0168775

Soethoudt, Marjolein; Grether, Uwe; Fingerle, Jürgen; Grim, Travis W; Fezza, Filomena; de Petrocellis, Luciano; Ullmer, Christoph; Rothenhäusler, Benno; Perret, Camille; van Gils, Noortje; Finlay, David; MacDonald, Christa; Chicca, Andrea; Gens, Marianela Dalghi; Stuart, Jordyn; de Vries, Henk; Mastrangelo, Nicolina; Xia, Lizi; Alachouzos, Georgios; Baggelaar, Marc P; ... (2017). Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nature communications, 8(13958), p. 13958. Nature Publishing Group 10.1038/ncomms13958

Gottier, Petra; González Salgado, Amaia; Menon, Anant K; Liu, Yuk-Chien; Acosta-Serrano, Alvaro; Bütikofer, Peter (2017). RFT1 affects GPI anchor glycosylation. Journal of biological chemistry, 292(3), pp. 1103-1111. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.758367

Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2017). Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Pflügers Archiv : European journal of physiology, 469(2), pp. 225-233. Springer 10.1007/s00424-016-1923-5

Martínez-Pacheco, Heidy; Ramírez-Galicia, Guillermo; Vergara-Arias, Midalia; Gertsch, Jürg; Fragoso-Vázquez, Jonathan Manuel; Méndez-Luna, David; Abujamra, A L; Cristina, Cabrera-Pérez Laura; Cecilia, Rosales-Hernández Martha; Mendoza-Lujambio, I; Correa-Basurto, José (2017). Docking and QSAR studies of aryl-valproic acid derivatives to identify anti-proliferative agents targeting the HDAC8. Anti-cancer agents in medicinal chemistry, 17(7), pp. 927-940. Bentham Science Publishers

Chen, Songjie; Huang, Xiao; Decurtins, Silvio; Albrecht, Christiane; Liu, Shi-Xia (2017). A terpy-functionalized benzodifuran-based fluorescent probe for in vitro monitoring cellular Zn(II) uptake. Polyhedron, 134, pp. 287-294. Elsevier 10.1016/j.poly.2017.06.037

Kind, Marcus Johann; Klukowska-Rötzler, Jolanta; Berezowska, Sabina Anna; Arcaro, Alexandre; Charles, Roch-Philippe (2017). Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis. PLoS ONE, 12(10), e0187308. Public Library of Science 10.1371/journal.pone.0187308

Baur, Roland; Sigel, Erwin (2017). Low Expression in Xenopus Oocytes and Unusual Functional Properties of α1β2γ2 GABAA Receptors with Non-Conventional Subunit Arrangement. PLoS ONE, 12(1), e0170572. Public Library of Science 10.1371/journal.pone.0170572

Maldifassi, Maria Constanza; Wongsamitkul, Nisa; Baur, Roland; Sigel, Erwin (2016). Xenopus Oocytes: Optimized Methods for Microinjection, Removal of Follicular Cell Layers, and Fast Solution Changes in Electrophysiological Experiments. Journal of visualized experiments(118) MYJoVE Corporation 10.3791/55034

Deisl, Christine; Anderegg, Manuel; Albano, Giuseppe; Lüscher, Benjamin; Cerny, David; Soria Maldonado, Rodrigo; Bouillet, Elisa; Rimoldi, Stefano; Scherrer, Urs; Fuster, Daniel Guido (2016). Loss of Sodium/Hydrogen Exchanger NHA2 Exacerbates Obesity- and Aging-Induced Glucose Intolerance in Mice. PLoS ONE, 11(9), e0163568. Public Library of Science 10.1371/journal.pone.0163568

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Gapsys, Vytautas; Ucurum Fotiadis, Zöhre; de Groot, Bert L; Fotiadis, Dimitrios José (2016). Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(37), pp. 10358-10363. National Academy of Sciences NAS 10.1073/pnas.1605442113

Alferink, Judith; Specht, Sabine; Arends, Hannah; Schumak, Beatrix; Schmidt, Kim; Ruland, Christina; Lundt, Ramona; Kemter, Andrea; Dlugos, Andrea; Kuepper, Janina M; Poppensieker, Karola; Findeiss, Matthias; Albayram, Önder; Otte, David-M; Marazzi, Janine; Gertsch, Jürg; Förster, Irmgard; Maier, Wolfgang; Scheu, Stefanie; Hoerauf, Achim; ... (2016). Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism. Journal of biological chemistry, 291(37), pp. 19517-19531. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.746594

Bertran-Vicente, Jordi; Penkert, Martin; Nieto-Garcia, Olaia; Jeckelmann, Jean-Marc; Schmieder, Peter; Krause, Eberhard; Hackenberger, Christian P R (2016). Chemoselective synthesis and analysis of naturally occurring phosphorylated cysteine peptides. Nature communications, 7, p. 12703. Nature Publishing Group 10.1038/ncomms12703

Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2016). Molecular mode of action of CGS 9895 at α1 β2 γ2 GABAA receptors. Journal of neurochemistry, 138(5), pp. 722-730. Wiley 10.1111/jnc.13711

Mu, Linjing; Müller Herde, Adrienne; Rüefli, Pascal; Sladojevich, Filippo; Sephton, Selena Milicevic; Krämer, Stefanie D.; Thompson, Andrew James; Schibli, Roger; Ametamey, Simon M.; Lochner, Martin (2016). Synthesis and Pharmacological Evaluation of [11C]granisetron and [18F]fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging. ACS chemical neuroscience, 7(11), pp. 1552-1564. American Chemical Society 10.1021/acschemneuro.6b00192

Wongsamitkul, Nisa; Baur, Roland; Sigel, Erwin (2016). Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors. Journal of biological chemistry, 291(35), pp. 18474-18483. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.738906

Eichel, Catherine A; Beuriot, Adeline; Chevalier, Morgan Yoann Edwin; Rougier, Jean-Sébastien; Louault, Florent; Dilanian, Gilles; Amour, Julien; Coulombe, Alain; Abriel, Hugues; Hatem, Stéphane N; Balse, Elise (2016). Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circulation research, 119(4), pp. 544-556. Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.116.309254

Jantsch, Andrea; Nieto, Lidia; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth; Jiménez-Barbero, Jesús; Díaz, J Fernando; Canales, Ángeles; Altmann, Karl-Heinz (2016). Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones). Molecules, 21(8) MDPI 10.3390/molecules21081010

Clemençon, Benjamin; Fine, Michael; Hediger, Matthias (2016). Conservation of the oligomeric state of native VDAC1 in detergent micelles. Biochimie, 127, pp. 163-172. Elsevier Masson SAS 10.1016/j.biochi.2016.05.015

Lochner, Martin; Jack, Thomas; Simonin, Jonathan; Leuenberger, Michele; Rüefli, Pascal; Bur-Cecilio Hechavarria, Yamileidi; Ruepp, Marc-David; Thompson, Andrew J. (August 2016). Investigation of the interaction between 5-HT3R and its modulators: progress in understanding the agonist binding site. CHIMIA, 70(7/8), MC121. Schweizerische Chemische Gesellschaft

Leuenberger, Michele; Ritler, Andreas; Aerni, Valerie; Metzger, Simon G.; Ruepp, Marc-David; Lochner, Martin (August 2016). New insights into glutamate transport in brain: Concise asymmetric synthesis of TFB-TBOA and photoaffinity probes. CHIMIA, 70(7/8), MC123. Schweizerische Chemische Gesellschaft

Schild, Achille; Tscherrig, Dominic Armin; Wenger, Nicolas; Rajesh, Rajesh; Lüscher, Benjamin; Hediger, Matthias; Lochner, Martin (August 2016). Design, synthesis and pharmacological characterization of novel store-operated calcium channel (SOCE) modulators. CHIMIA, 70(7/8), MC125. Schweizerische Chemische Gesellschaft

Gambaro, Giovanni; Croppi, Emanuele; Coe, Fredric; Lingeman, James; Moe, Orson; Worcester, Elen; Buchholz, Noor; Bushinsky, David; Curhan, Gary C; Ferraro, Pietro Manuel; Fuster, Daniel Guido; Goldfarb, David S; Heilberg, Ita Pfeferman; Hess, Bernard; Lieske, John; Marangella, Martino; Milliner, Dawn; Preminger, Glen M; Reis Santos, Jose' Manuel; Sakhaee, Khashayar; ... (2016). Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement. Journal of nephrology JN, 29(6), pp. 715-734. Springer 10.1007/s40620-016-0329-y

Harder, Daniel; Hirschi, Stephan; Ucurum Fotiadis, Zöhre; Goers, Roland; Meier, Wolfgang; Müller, Daniel J; Fotiadis, Dimitrios José (2016). Engineering a Chemical Switch into the Light-driven Proton Pump Proteorhodopsin by Cysteine Mutagenesis and Thiol Modification. Angewandte Chemie (International ed.), 55(31), pp. 8846-8849. Wiley-VCH 10.1002/anie.201601537

Gertsch, Jürg (2016). The Metabolic Plant Feedback Hypothesis: How Plant Secondary Metabolites Nonspecifically Impact Human Health. Planta medica, 82(11-12), pp. 920-929. Thieme 10.1055/s-0042-108340

Bertini, Simone; Chicca, Andrea; Arena, Chiara; Chicca, Stefano; Saccomanni, Giuseppe; Gertsch, Jürg; Manera, Clementina; Macchia, Marco (2016). Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands. European journal of medicinal chemistry, 116, pp. 252-266. Elsevier Masson SAS 10.1016/j.ejmech.2016.03.072

Huang, Xiao; Lüthi, Michael; Ontsouka, Edgar; Kallol, Sampada Arvindrao; Baumann, Marc Ulrich; Surbek, Daniel; Albrecht, Christiane (2016). Establishment of a confluent monolayer model with human primary trophoblast cells: novel insights into placental glucose transport. Molecular human reproduction MHR, 22(6), pp. 442-456. Oxford University Press 10.1093/molehr/gaw018

Dhayat, Nasser; Ackermann, Daniel; Pruijm, Menno; Ponte, Belen; Ehret, Georg; Guessous, Idris; Leichtle, Alexander Benedikt; Paccaud, Fred; Mohaupt, Markus; Fiedler, Martin; Devuyst, Olivier; Pechère-Bertschi, Antoinette; Burnier, Michel; Martin, Pierre-Yves; Bochud, Murielle; Vogt, Bruno; Fuster, Daniel Guido (2016). Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function. Kidney international, 90(3), pp. 648-657. Elsevier 10.1016/j.kint.2016.04.024

Hirschi, Stephan; Stauffer, Mirko; Harder, Daniel; Müller, Daniel J; Meier, Wolfgang; Fotiadis, Dimitrios José (2016). Engineering and Assembly of Protein Modules into Functional Molecular Systems. CHIMIA, 70(6), pp. 398-401. Schweizerische Chemische Gesellschaft 10.2533/chimia.2016.398

Wellnitz, Olga; Zbinden, Christina; Huang, Xiao; Bruckmaier, Rupert (2016). Short communication: Differential loss of bovine mammary epithelial barrier integrity in response to lipopolysaccharide and lipoteichoic acid. Journal of dairy science, 99(6), pp. 4851-4856. American Dairy Science Association 10.3168/jds.2016-10927

Maldifassi, Maria Constanza; Baur, Roland; Pierce, David; Nourmahnad, Anahita; Forman, Stuart A; Sigel, Erwin (2016). Novel positive allosteric modulators of GABAA receptors with anesthetic activity. Scientific Reports, 6(25943), p. 25943. Nature Publishing Group 10.1038/srep25943

Lochner, Martin; Thompson, Andrew James (2016). The muscarinic antagonists scopolamine and atropine are competitive antagonists at 5-HT3 receptors. Neuropharmacology, 108, pp. 220-228. Elsevier 10.1016/j.neuropharm.2016.04.027

Eisele, Nicole; Albrecht, Christiane; Mistry, Hiten Dhirubhai; Dick, Bernhard; Baumann, Marc Ulrich; Surbek, Daniel; Currie, Gemma; Delles, Christian; Mohaupt, Markus; Escher, Geneviève; Gennari-Moser, Carine (2016). Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. Elsevier 10.1016/j.placenta.2016.02.004

Oláh, Attila; Ambrus, Lídia; Nicolussi, Simon; Gertsch, Jürg; Tubak, Vilmos; Kemény, Lajos; Soeberdt, Michael; Abels, Christoph; Bíró, Tamás (2016). Inhibition of fatty acid amide hydrolase exerts cutaneous anti-inflammatory effects both in vitro and in vivo. Experimental dermatology, 25(4), pp. 328-330. Blackwell 10.1111/exd.12930

Gross, Josef Johann; Schwinn, Ann-Catherine; Schmitz-Hsu, F; Menzi, Fiona; Drögemüller, Cord; Albrecht, Christiane; Bruckmaier, Rupert (2016). Rapid Communication: Cholesterol deficiency-associated APOB mutation impacts lipid metabolism in Holstein calves and breeding bulls. Journal of animal science, 94(4), pp. 1761-1766. American Society of Animal Science 10.2527/jas.2016-0439

Gertsch, Jürg (2016). Editorial: Lung macrophages high on cannabinoids: jamming PAMs and taming TAMs? Journal of leukocyte biology, 99(4), pp. 518-520. Society for Leukocyte Biology 10.1189/jlb.3CE0915-409RR

Ross, Daniela; Altmann, Michael (2016). A fast protocol for purification of translating mRNAs. Methods, 107, pp. 57-62. Elsevier 10.1016/j.ymeth.2016.03.021

Rajesh, Rajesh; Hediger, Matthias; Demaurex, Nicolas (2016). Redox modulation of STIM-ORAI signaling. Cell calcium, 60(2), pp. 142-152. Elsevier 10.1016/j.ceca.2016.03.006

Dörr, Kathrin; Kilch, Tatiana; Kappel, Sven; Alansary, Dalia; Schwär, Gertrud; Niemeyer, Barbara A; Peinelt, Christine (2016). Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry. Science signaling, 9(418), ra25. American Association for the Advancement of Science 10.1126/scisignal.aaa9913

Chauhan, Neha; Farine, Luce; Pandey, Kalpana; Menon, Anant K; Bütikofer, Peter (2016). Lipid topogenesis - 35 years on. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(8), pp. 757-766. Elsevier 10.1016/j.bbalip.2016.02.025

Leuenberger, Michele; Ritler, Andreas; Simonin, Alexandre; Hediger, Matthias; Lochner, Martin (2016). Concise Asymmetric Synthesis and Pharmacological Characterization of All Stereoisomers of Glutamate Transporter Inhibitor TFB-TBOA and Synthesis of EAAT Photoaffinity Probes. ACS chemical neuroscience, 7(5), pp. 534-539. American Chemical Society 10.1021/acschemneuro.5b00311

Crockett, Sara; Baur, Roland; Kunert, Olaf; Belaj, Ferdinand; Sigel, Erwin (2016). A new chromanone derivative isolated from Hypericum lissophloeus (Hypericaceae) potentiates GABAA receptor currents in a subunit specific fashion. Bioorganic & medicinal chemistry, 24(4), pp. 681-685. Elsevier 10.1016/j.bmc.2015.12.037

Ontsouka, Edgar; Albrecht, Christiane; Bruckmaier, Rupert (2016). Invited review: Growth-promoting effects of colostrum in calves based on interaction with intestinal cell surface receptors and receptor-like transporters. Journal of dairy science, 99(6), pp. 4111-4123. American Dairy Science Association 10.3168/jds.2015-9741

Knight, Anthony; Hemmings, Jennifer Luise; Winfield, Ian; Leuenberger, Michele; Frattini, Eugenia; Frenguelli, Bruno G.; Dowell, Simon J.; Lochner, Martin; Ladds, Graham (2016). Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity. Journal of medicinal chemistry, 59(3), pp. 947-964. American Chemical Society 10.1021/acs.jmedchem.5b01402

Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2016). Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital. Neuropharmacology, 105, pp. 207-214. Elsevier 10.1016/j.neuropharm.2016.01.003

Albrecht, Christiane; Caniggia, I; Clifton, V; Göhner, C; Harris, L; Hemmings, D; Jawerbaum, A; Johnstone, E; Jones, H; Keelan, J; Lewis, R; Mitchell, M; Murthi, P; Powell, T; Saffery, R; Smith, R; Vaillancourt, C; Wadsack, C; Salomon, C (2016). IFPA meeting 2015 workshop report IV: Nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid mediators and placental function. Placenta, 48 Suppl 1, S12-S16. Elsevier 10.1016/j.placenta.2016.01.003

Ontsouka, Edgar; Bertschi, Janique Sabina; Huang, Xiao; Lüthi, Michael; Müller, Stefan Jürg; Albrecht, Christiane (2016). Can widely used cell type markers predict the suitability of immortalized or primary mammary epithelial cell models? Biological research, 49(1), p. 1. BioMed Central 10.1186/s40659-015-0063-2

Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356

Rau, Mark; Nicolussi, Simon; Chicca, Andrea; Gertsch, Jürg (2016). Assay of Endocannabinoid Uptake. In: Maccarrone, Mauro (ed.) Endocannabinoid Signaling. Methods and Protocols. Methods in Molecular Biology: Vol. 1412 (pp. 191-203). New York: Springer 10.1007/978-1-4939-3539-0_20

Boggavarapu, Venkata Ravi Naga Rajendr; Hirschi, Stephan; Harder, Daniel; Meury, Marcel; Ucurum Fotiadis, Zöhre; Bergeron, Marc; Fotiadis, Dimitrios José (2016). Purification of Human and Mammalian Membrane Proteins Expressed in Xenopus laevis Frog Oocytes for Structural Studies. In: Mus-Veteau, Isabelle (ed.) Heterologous Expression of Membrane Proteins. Methods and Protocols. Methods in Molecular Biology: Vol. 1432 (pp. 223-242). New York: Springer 10.1007/978-1-4939-3637-3_14

Eltschinger, Sandra; Bütikofer, Peter; Altmann, Michael (2016). Translation Elongation and Termination: 2 Are They Conserved Processes? In: Hernández, Greco; Jagus, Rosemary (eds.) Evolution of The Protein Synthesis Machinery and Its Regulation (pp. 277-311). Springer International 10.1007/978-3-319-39468-8_13

Ross, Daniela; Altmann, Michael (2016). eIF4Es and Their Interactors from Yeast Species. In: Hernández, Greco; Jagus, Rosemary (eds.) Evolution of The Protein Synthesis Machinery and Its Regulation (pp. 143-164). Sprinter International 10.1007/978-3-319-39468-8_7

Kilch, Tatiana; Kappel, Sven; Peinelt, Christine (2016). Regulation of Ca(2+) signaling in prostate cancer cells. Channels, 10(3), pp. 170-171. Taylor & Francis 10.1080/19336950.2015.1137176

Simonin, Alexandre; Montalbetti, Nicolas; Gyimesi, Gergely; Pujol Gimenez, Jonai; Hediger, Matthias (2015). The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2. Journal of biological chemistry, 290(51), pp. 30464-30474. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M115.689836

Liechti, Matthias E; Quednow, Boris B; Liakoni, Evangelia; Dornbierer, Dario; von Rotz, Robin; Gachet Otanez, Maria Salomé; Gertsch, Jürg; Seifritz, Erich; Bosch, Oliver G (2015). Pharmacokinetics and pharmacodynamics of γ-hydroxybutyrate in healthy subjects. British journal of clinical pharmacology, 81(5), pp. 980-988. Wiley-Blackwell 10.1111/bcp.12863

Holzmann, Christian; Kappel, Sven; Kilch, Tatiana; Jochum, Marcus Martin; Urban, Sabine Katharina; Jung, Volker; Stöckle, Michael; Rother, Karen; Greiner, Markus; Peinelt, Christine (2015). Transient receptor potential melastatin 4 channel contributes to migration of androgen-insensitive prostate cancer cells. OncoTarget, 6(39), pp. 41783-41793. Impact Journals LLC 10.18632/oncotarget.6157

Bosch, Oliver G; Eisenegger, Christoph; Gertsch, Jürg; von Rotz, Robin; Dornbierer, Dario; Gachet Otanez, Maria Salomé; Heinrichs, Markus; Wetter, Thomas C; Seifritz, Erich; Quednow, Boris B (2015). Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone. Psychoneuroendocrinology, 62, pp. 1-10. Elsevier 10.1016/j.psyneuen.2015.07.167

Gachet Otanez, Maria Salomé; Gertsch, Jürg (2015). Quantitative analysis of arachidonic acid, endocannabinoids, N-acylethanolamines and steroids in biological samples by LCMS/MS: Fit to purpose. Journal of chromatography. B - analytical technologies in the biomedical and life sciences, 1012-1013, pp. 215-221. Elsevier 10.1016/j.jchromb.2015.11.013

Farine, Luce; Niemann, Moritz; Schneider, André; Bütikofer, Peter (2015). Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei. Scientific Reports, 5(1), p. 16787. Nature Publishing Group 10.1038/srep16787

Jain, Arjun; Albrecht, Christiane (2015). Importance of cholesterol and cholesterol transporters in the placental trophoblast during pregnancy. In: Duttaroy, Asim K.; Basak, Sanjay (eds.) Human Placental Trophoblasts: Impact of Maternal Nutrition (pp. 129-144). CRC Press

Looser, V; Bruhlmann, B; Bumbak, F; Stenger, C; Costa, M; Camattari, A; Fotiadis, Dimitrios José; Kovar, K (2015). Cultivation strategies to enhance productivity of Pichia pastoris: A review. Biotechnology advances, 33(6 Pt 2), pp. 1177-1193. Elsevier 10.1016/j.biotechadv.2015.05.008

Holzmann, Christian; Kilch, Tatiana; Kappel, Sven; Dörr, Kathrin; Jung, Volker; Stöckle, Michael; Bogeski, Ivan; Peinelt, Christine (2015). Differential Redox Regulation of Ca²⁺ Signaling and Viability in Normal and Malignant Prostate Cells. Biophysical journal, 109(7), pp. 1410-1419. Biophysical Society 10.1016/j.bpj.2015.08.006

Dhayat, Nasser; Simonin, Alexandre; Anderegg, Manuel; Pathare, Ganesh Tukaram; Lüscher, Benjamin; Deisl, Christine; Albano, Giuseppe; Mordasini, David; Hediger, Matthias; Surbek, Daniel; Vogt, Bruno; Sass, Jörn; Kloeckener-Gruissem, Barbara; Fuster, Daniel Guido (2015). Mutation in the Monocarboxylate Transporter 12 Gene Affects Guanidinoacetate Excretion but Does Not Cause Glucosuria. Journal of the American Society of Nephrology, 27(5), pp. 1426-1436. American Society of Nephrology 10.1681/ASN.2015040411

Iakovenko, Roman O; Kazakova, Anna N; Muzalevskiy, Vasiliy M; Ivanov, Alexander Yu; Boyarskaya, Irina A; Chicca, Andrea; Petrucci, Vanessa; Gertsch, Jürg; Krasavin, Mikhail; Starova, Galina L; Zolotarev, Andrey A; Avdontceva, Margarita S; Nenajdenko, Valentine G; Vasilyev, Aleksander V (2015). Reactions of CF3-enones with arenes under superelectrophilic activation: a pathway to trans-1,3-diaryl-1-CF3-indanes, new cannabinoid receptor ligands. Organic & biomolecular chemistry, 13(33), pp. 8827-8842. Royal Society of Chemistry 10.1039/c5ob01072a

Kalbermatter, David; Jeckelmann, Jean-Marc; Chiu, Po-Lin; Ucurum Fotiadis, Zöhre; Walz, Thomas; Fotiadis, Dimitrios José (2015). 2D and 3D crystallization of the wild-type IIC domain of the glucose PTS transporter from Escherichia coli. Journal of structural biology, 191(3), pp. 376-380. Elsevier 10.1016/j.jsb.2015.08.003

Haeberlin, Andreas; Fuster, Daniel Guido (2015). Abdominal pain, emesis and dyspnea after kidney transplantation. Nephrology, 20(8), pp. 582-583. Wiley-Blackwell 10.1111/nep.12484

Steinmann, Michael Eduard; González Salgado, Amaia; Bütikofer, Peter; Mäser, Pascal; Sigel, Erwin (2015). A heteromeric potassium channel involved in the modulation of the plasma membrane potential is essential for the survival of African trypanosomes. FASEB journal, 29(8), pp. 3228-3237. Federation of American Societies for Experimental Biology 10.1096/fj.15-271353

Middendorp, Simon; Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2015). Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site. Neuropharmacology, 95, pp. 459-467. Elsevier 10.1016/j.neuropharm.2015.04.027

César-Razquin, Adrián; Snijder, Berend; Frappier-Brinton, Tristan; Isserlin, Ruth; Gyimesi, Gergely; Bai, Xiaoyun; Reithmeier, Reinhart A; Hepworth, David; Hediger, Matthias; Edwards, Aled M; Superti-Furga, Giulio (2015). A Call for Systematic Research on Solute Carriers. Cell, 162(3), pp. 478-487. Cell Press 10.1016/j.cell.2015.07.022

Fotiadis, Dimitrios José; Engel, Andreas (2015). Two-Dimensional Crystallisation of Membrane Proteins and Structural Assessment. In: eLS (pp. 1-10). John Wiley & Sons, Ltd.

Damseh, Nadirah; Simonin, Alexandre; Jalas, Chaim; Picoraro, Joseph A; Shaag, Avraham; Cho, Megan T; Yaacov, Barak; Neidich, Julie; Al-Ashhab, Motee; Juusola, Jane; Bale, Sherri; Telegrafi, Aida; Retterer, Kyle; Pappas, John G; Moran, Ellen; Cappell, Joshua; Anyane Yeboa, Kwame; Abu-Libdeh, Bassam; Hediger, Matthias; Chung, Wendy K; ... (2015). Mutations in SLC1A4, encoding the brain serine transporter, are associated with developmental delay, microcephaly and hypomyelination. Journal of medical genetics, 52(8), pp. 541-547. BMJ Publishing Group 10.1136/jmedgenet-2015-103104

González Salgado, Amaia; Steinmann, Michael Eduard; Major, Louise L; Sigel, Erwin; Reymond, Jean-Louis; Smith, Terry K; Bütikofer, Peter (2015). Trypanosoma brucei Bloodstream Forms Depend upon Uptake of myo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth. Eukaryotic cell, 14(6), pp. 616-624. American Society for Microbiology ASM 10.1128/EC.00038-15

Petrosyan, Rafayel; Bippes, Christian A; Walheim, Stefan; Harder, Daniel; Fotiadis, Dimitrios José; Schimmel, Thomas; Alsteens, David; Müller, Daniel J (2015). Single-molecule force spectroscopy of membrane proteins from membranes freely spanning across nanoscopic pores. Nano letters, 15(5), pp. 3624-3633. American Chemical Society 10.1021/acs.nanolett.5b01223

de Macêdo, Juan P.; Schumann-Burkard, Gabriela; Niemann, Moritz; Barrett, Michael P.; Vial, Henri; Mäser, Pascal; Roditi, Isabel; Schneider, André; Bütikofer, Peter; Horn, David (2015). An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei. PLoS pathogens, 11(5), e1004875. Public Library of Science 10.1371/journal.ppat.1004875

Del Carlo, S; Manera, C; Chicca, Andrea; Arena, C; Bertini, S; Burgalassi, S; Tampucci, S; Gertsch, Jürg; Macchia, M; Saccomanni, G (2015). Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase. Journal of pharmaceutical and biomedical analysis, 108, pp. 113-121. Pergamon Press 10.1016/j.jpba.2015.02.007

Wang, Yuqing; Serricchio, Mauro; Jauregui, Miluska; Shanbhag, Riya; Stoltz, Tasha; Di Paolo, Caitlin T; Kim, Peter K; McQuibban, G Angus (2015). Deubiquitinating enzymes regulate PARK2-mediated mitophagy. Autophagy, 11(4), pp. 595-606. Taylor & Francis 10.1080/15548627.2015.1034408

Hofer Reyes, Stefanie; Ralvenius, William T; Gachet Otanez, Maria Salomé; Fritschy, Jean-Marc; Zeilhofer, Ulrich; Gertsch, Jürg (2015). Localization and production of peptide endocannabinoids in the rodent CNS and adrenal medulla. Neuropharmacology, 98, pp. 78-89. Elsevier 10.1016/j.neuropharm.2015.03.021

Clemençon, Benjamin; Fine, Michael; Schneider, Philipp; Hediger, Matthias (2015). Rapid method to express and purify human membrane protein using the Xenopus oocyte system for functional and low-resolution structural analysis. Methods in enzymology, 556, pp. 241-265. Academic Press 10.1016/bs.mie.2014.12.011

Jack, Thomas; Simonin, Jonathan; Ruepp, Marc-David; Thompson, Andrew James; Gertsch, Jürg; Lochner, Martin (2015). Characterizing New Fluorescent Tools for Studying 5-HT3 Receptor Pharmacology. Neuropharmacology, 90, pp. 63-73. Elsevier 10.1016/j.neuropharm.2014.11.007

Andrieu, Thomas; Mani, Orlando; Göpfert, Christine; Bertolini, Reto; Güttinger, Andreas; Setoud, Raschid; Uh, Kayla Y; Baker, Michael E; Frey, Felix J; Frey, Brigitte M (2015). Detection and functional portrayal of a novel class of dihydrotestosterone derived selective progesterone receptor modulators (SPRM). Journal of steroid biochemistry and molecular biology, 147, pp. 111-123. Elsevier 10.1016/j.jsbmb.2014.12.009

Burda, Paul-Christian; Rölli, Matthias; Schaffner, Marco; Khan, Shahid M; Janse, Chris J; Heussler, Volker (2015). A Plasmodium phospholipase is involved in disruption of the liver stage parasitophorous vacuole membrane. PLoS pathogens, 11(3), e1004760. Public Library of Science 10.1371/journal.ppat.1004760

Gachet Otanez, Maria Salomé; Rhyn, Peter; Bosch, Oliver G; Quednow, Boris B; Gertsch, Jürg (2015). A quantitiative LC-MS/MS method for the measurement of arachidonic acid, prostanoids, endocannabinoids, N-acylethanolamines and steroids in human plasma. Journal of chromatography. B - analytical technologies in the biomedical and life sciences, 976-977, pp. 6-18. Elsevier 10.1016/j.jchromb.2014.11.001

Shameer, Sanu; Logan-Klumpler, Flora J; Vinson, Florence; Cottret, Ludovic; Merlet, Benjamin; Achcar, Fiona; Boshart, Michael; Berriman, Matthew; Breitling, Rainer; Bringaud, Frédéric; Bütikofer, Peter; Cattanach, Amy M; Bannerman-Chukualim, Bridget; Creek, Darren J; Crouch, Kathryn; de Koning, Harry P; Denise, Hubert; Ebikeme, Charles; Fairlamb, Alan H; Ferguson, Michael A J; ... (2015). TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. Nucleic acids research, 43(DBissue), D637-D644. Information Retrieval Ltd. 10.1093/nar/gku944

Baur, Roland; Beech, Robin; Sigel, Erwin; Rufener, Lucien (2015). Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors. Molecular pharmacology, 87(1), pp. 96-102. American Society for Pharmacology and Experimental Therapeutics 10.1124/mol.114.095653

Nicolussi, Simon; Gertsch, Jürg (2015). Endocannabinoid transport revisited. In: Litwack, Gerald (ed.) Vitamins and Hormones. Hormones and Transport Systems: Vol. 98 (pp. 441-485). Elsevier Inc. 10.1016/bs.vh.2014.12.011

Patsenker, Eleanora; Sachse, Philip; Chicca, Andrea; Gachet Otanez, Maria Salomé; Schneider, Vreni; Mattsson, Johan; Lanz, Christian; Worni, Mathias; De Gottardi, Andrea; Semmo, Mariam; Hampe, Jochen; Schafmayer, Clemens; Brenneisen, Rudolf Max; Gertsch, Jürg; Stickel, Felix; Semmo, Nasser (2015). Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation. International journal of molecular sciences, 16(4), pp. 7057-7076. MDPI 10.3390/ijms16047057

Imhof, Simon; Vu Nguyen, Xuan Lan; Bütikofer, Peter; Roditi, Isabel (2015). A glycosylation mutant of Trypanosoma brucei links social motility defects in vitro to impaired colonisation of tsetse in vivo. Eukaryotic cell, 14(6), pp. 588-592. American Society for Microbiology ASM 10.1128/EC.00023-15

Albano, Giuseppe; Moor, Matthias; Dolder, Silvia; Siegrist, Mark; Wagner, Carsten A.; Biber, Jürg; Hernando, Nati; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2015). Sodium-Dependent Phosphate Transporters in Osteoclast Differentiation and Function. PLoS ONE, 10(4), e0125104. Public Library of Science 10.1371/journal.pone.0125104

Simonin, Céline; Awale, Mahendra; Brand, Michael; van Deursen, Ruud; Schwartz, Julian; Fine, Michael; Kovacs, Gergely; Häfliger, Pascal; Gyimesi, Gergely; Sithampari, Abilashan; Charles, Roch-Philippe; Hediger, Matthias; Reymond, Jean-Louis (2015). Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method. Angewandte Chemie (International ed.), 54(49), pp. 14748-14752. Wiley-VCH 10.1002/anie.201507320

Montalbetti, Nicolas; Simonin, Alexandre; Simonin, Céline; Awale, Mahendra; Reymond, Jean-Louis; Hediger, Matthias (2015). Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2. Biochemical pharmacology, 96(3), pp. 216-224. Elsevier 10.1016/j.bcp.2015.05.002

Dhayat, Nasser; Schaller, André; Albano, Giuseppe; Poindexter, John; Griffith, Carolyn; Pasch, Andreas; Gallati, Sabina; Vogt, Bruno; Moe, Orson; Fuster, Daniel Guido (2015). The Vacuolar H+-ATPase B1 Subunit Polymorphism p.E161K Associates with Impaired Urinary Acidification in Recurrent Stone Formers. Journal of the American Society of Nephrology, 27(5), pp. 1544-1554. Lippincott Williams & Wilkins 10.1681/ASN.2015040367

Chicca, Andrea; Gachet Otanez, Maria Salomé; Petrucci, Vanessa; Schuehly, Wolfgang; Charles, Roch-Philippe; Gertsch, Jürg (2015). 4'-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation. Journal of neuroinflammation, 12, p. 89. BioMed Central 10.1186/s12974-015-0307-7

Boggavarapu, Venkata Ravi Naga Rajendr; Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2015). Role of electrostatic interactions for ligand recognition and specificity of peptide transporters. BMC biology, 13(58), p. 58. BioMed Central 10.1186/s12915-015-0167-8

Bosshart, Patrick; Engel, Andreas; Fotiadis, Dimitrios José (2015). High-resolution atomic force microscopy imaging of rhodopsin in rod outer segment disk membranes. Methods in molecular biology, 1271, pp. 189-203. Humana Press 10.1007/978-1-4939-2330-4_13

Gross, Josef Johann; Kessler, Evelyne; Albrecht, Christiane; Bruckmaier, Rupert (2015). Response of the cholesterol metabolism to a negative energy balance in dairy cows depends on the lactational stage. PLoS ONE, 10(6), e0121956. Public Library of Science 10.1371/journal.pone.0121956

Serricchio, Mauro; Schmid, Adrien W; Steinmann, Michael Eduard; Sigel, Erwin; Rauch, Monika; Julkowska, Daria; Bonnefoy, Serge; Fort, Cécile; Bastin, Philippe; Bütikofer, Peter (2015). Flagellar membranes are rich in raft-forming phospholipids. Biology open BiO, 4(9), pp. 1143-1153. Company of Biologists 10.1242/bio.011957

Fedurco, Milan; Gregorová, Jana; Šebrlová, Kristýna; Kantorová, Jana; Peš, Ondřej; Baur, Roland; Sigel, Erwin; Táborská, Eva (2015). Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. Biochemistry research international, 2015(617620), p. 617620. Hindawi Publishing Corporation 10.1155/2015/617620

Charles, Roch-Philippe (2015). Overview of Genetically Engineered Mouse Models of Papillary and Anaplastic Thyroid Cancers: Enabling Translational Biology for Patient Care Improvement. Current protocols in pharmacology, 69, 14.33.1-14.33.14. Wiley 10.1002/0471141755.ph1433s69

Salm, Fabiana; Dimitrova, Valeriya; von Bueren, André O; Cwiek, Paulina; Rehrauer, Hubert; Djonov, Valentin; Anderle, Pascale; Arcaro, Alexandre (2015). The Phosphoinositide 3-Kinase p110α Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma. PLoS ONE, 10(4), e0123958. Public Library of Science 10.1371/journal.pone.0123958

Fuchs, Alexander; Baur, Roland; Schoeder, Clara; Sigel, Erwin; Müller, Christa E (2014). Structural analogues of the natural products magnolol and honokiol as potent allosteric potentiators of GABA(A) receptors. Bioorganic & medicinal chemistry, 22(24), pp. 6908-6917. Elsevier 10.1016/j.bmc.2014.10.027

Nicolussi, Simon; Chicca, Andrea; Rau, Mark; Rihs, Sabine; Soeberdt, Michael; Abels, Christoph; Gertsch, Jürg (2014). Correlating FAAH and anandamide cellular uptake inhibition using N-alkylcarbamate inhibitors: from ultrapotent to hyperpotent. Biochemical pharmacology, 92(4), pp. 669-689. Elsevier 10.1016/j.bcp.2014.09.020

Dumusc, S D; Ontsouka, Edgar; Schnyder, M; Hartnack, S; Albrecht, C; Bruckmaier, Rupert; Burgener, I A (2014). Cyclooxygenase-2 and 5-lipoxygenase in dogs with chronic enteropathies. Journal of veterinary internal medicine, 28(6), pp. 1684-1691. Wiley-Blackwell 10.1111/jvim.12463

Clemençon, Benjamin; Lüscher, Benjamin; Fine, Michael; Baumann, Marc Ulrich; Surbek, Daniel; Bonny, Olivier; Hediger, Matthias (2014). Expression, purification, and structural insights for the human uric acid transporter, GLUT9, using the Xenopus laevis oocytes system. PLoS ONE, 9(10), e108852. Public Library of Science 10.1371/journal.pone.0108852

Rosati, Ornelio; Messina, Federica; Pelosi, Azzurra; Curini, Massimo; Petrucci, Vanessa; Gertsch, Jürg; Chicca, Andrea (2014). One-pot heterogeneous synthesis of Δ(3)-tetrahydrocannabinol analogues and xanthenes showing differential binding to CB(1) and CB(2) receptors. European journal of medicinal chemistry, 85, pp. 77-86. Elsevier Masson SAS 10.1016/j.ejmech.2014.07.062

Baur, Roland; Schuehly, Wolfgang; Sigel, Erwin (2014). Moderate concentrations of 4-O-methylhonokiol potentiate GABAA receptor currents stronger than honokiol. Biochimica et biophysica acta (BBA) - general subjects, 1840(10), pp. 3017-3021. Elsevier 10.1016/j.bbagen.2014.06.016

Meury, Marcel; Costa Torres, Meritxell; Harder, Daniel; Stauffer, Mirko; Jeckelmann, Jean-Marc; Brühlmann, Béla; Rosell, Albert; Ilgü, Hüseyin; Kovar, Karin; Palacín, Manuel; Fotiadis, Dimitrios José (2014). Detergent-induced stabilization and improved 3D map of the human heteromeric amino acid transporter 4F2hc-LAT2. PLoS ONE, 9(10), e109882. Public Library of Science 10.1371/journal.pone.0109882

Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2014). 2D and 3D crystallization of a bacterial homologue of human vitamin C membrane transport proteins. Journal of structural biology, 188(1), pp. 87-91. Elsevier 10.1016/j.jsb.2014.08.004

Sing, Anson; Tsatskis, Yonit; Fabian, Lacramioara; Hester, Ian; Rosenfeld, Robyn; Serricchio, Mauro; Yau, Norman; Bietenhader, Maïlis; Shanbhag, Riya; Jurisicova, Andrea; Brill, Julie A; McQuibban, G Angus; McNeill, Helen (2014). The atypical cadherin fat directly regulates mitochondrial function and metabolic state. Cell, 158(6), pp. 1293-1308. Cell Press 10.1016/j.cell.2014.07.036

Kessler, Evelyne; Gross, Josef Johann; Bruckmaier, Rupert; Albrecht, Christiane (2014). Cholesterol metabolism, transport, and hepatic regulation in dairy cows during transition and early lactation. Journal of dairy science, 97(9), pp. 5481-5490. American Dairy Science Association 10.3168/jds.2014-7926

Huang, Xiao; Lüthi, Michael; Ontsouka, Edgar; Baumann, Marc Ulrich; Surbek, Daniel; Albrecht, Christiane (September 2014). Materno-fetal nutrient transfer across primary human trophoblast layer. Placenta, 35, A97-A98. Elsevier

Lüscher, Benjamin; Fine, Michael; Marini, Camilla; Clemençon, Benjamin; Albrecht, Christiane; Hediger, Matthias; Surbek, Daniel; Baumann, Marc Ulrich (September 2014). PLACENTAL URIC ACID TRANSPORTER GLUT9 IS MODULATED BY FREE IODINE. Placenta, 35, A97-A97. Elsevier

Marini, Camilla; Lüscher, Benjamin; Jörger Messerli, Marianne; Sager, Ruth; Huang, Xiao; Gertsch, Jürg; Hediger, Matthias; Albrecht, Christiane; Baumann, Marc Ulrich; Surbek, Daniel (September 2014). PLACENTAL GLUCOSE TRANSPORTER (GLUT)-1 REGULATION IN PREECLAMPSIA. Placenta, 35, A83-A84. Elsevier

Beck, Andreas; Fleig, Andrea; Penner, Reinhold; Peinelt, Christine (2014). Regulation of endogenous and heterologous Ca²⁺ release-activated Ca²⁺ currents by pH. Cell calcium, 56(3), pp. 235-243. Elsevier 10.1016/j.ceca.2014.07.011

Middendorp, Simon; Hurni, Evelyn; Schönberger, Matthias; Stein, Marco; Pangerl, Michael; Trauner, Dirk; Sigel, Erwin (2014). Relative positioning of classical benzodiazepines to the γ2-subunit of GABAA receptors. ACS Chemical Biology, 9(8), pp. 1846-1853. American Chemical Society 10.1021/cb500186a

Middendorp, Simon; Puthenkalam, Roshan; Baur, Roland; Ernst, Margot; Sigel, Erwin (2014). Accelerated discovery of novel benzodiazepine ligands by experiment-guided virtual screening. ACS Chemical Biology, 9(8), pp. 1854-1859. American Chemical Society 10.1021/cb5001873

Jain, Arjun; Schneider, Henning; Aliyev, Eldar; Soydemir, Fatimah; Baumann, Marc Ulrich; Surbek, Daniel; Hediger, Matthias; Brownbill, Paul; Albrecht, Christiane (2014). Hypoxic treatment of human dual placental perfusion induces a preeclampsia-like inflammatory response. Laboratory investigation, 94(8), pp. 873-880. Nature Publishing Group 10.1038/labinvest.2014.76

Hajdu, Zsanett; Nicolussi, Simon; Rau, Mark; Lorántfy, László; Forgo, Peter; Hohmann, Judit; Csupor, Dezső; Gertsch, Jürg (2014). Identification of endocannabinoid system-modulating N-alkylamides from Heliopsis helianthoides var. scabra and Lepidium meyenii. Journal of natural products, 77(7), pp. 1663-1669. American Chemical Society 10.1021/np500292g

Chicca, Andrea; Caprioglio, Diego; Minassi, Alberto; Petrucci, Vanessa; Appendino, Giovanni; Taglialatela-Scafati, Orazio; Gertsch, Jürg (2014). Functionalization of β-caryophyllene generates novel polypharmacology in the endocannabinoid system. ACS Chemical Biology, 9(7), pp. 1499-1507. American Chemical Society 10.1021/cb500177c

Mathieu, Christoph; González Salgado, Amaia; Wirdnam, Corina; Meier, Stefan; Suter, Marianne; Inbar, Ehud; Mäser, Pascal; Zilberstein, Dan; Sigel, Erwin; Bütikofer, Peter; Rentsch, Doris (2014). Trypanosoma brucei eflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids. Biochemical journal, 463(1), pp. 9-18. Portland Press 10.1042/BJ20140719

Deisl, Christine; Albano, Giuseppe; Fuster, Daniel Guido (2014). Role of Na/H exchange in insulin secretion by islet cells. Current Opinion in Nephrology and Hypertension, 23(4), pp. 406-410. Lippincott Williams & Wilkins 10.1097/01.mnh.0000447013.36475.96

Malsure, Sumedha; Wang, Qing; Charles, Roch-Philippe; Sergi, Chloe; Perrier, Romain; Christensen, Birgitte Mønster; Maillard, Marc; Rossier, Bernard C; Hummler, Edith (2014). Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance. Journal of the American Society of Nephrology, 25(7), pp. 1453-1464. Lippincott Williams & Wilkins 10.1681/ASN.2013090936

Charles, Roch-Philippe; Silva, Jillian; Iezza, Gioia; Phillips, Wayne A; McMahon, Martin (2014). Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis. Molecular cancer research, 12(7), pp. 979-986. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-14-0158-T

Alansary, Dalia; Kilch, Tatiana; Holzmann, Christian; Peinelt, Christine; Hoth, Markus; Lis, Annette (2014). Patch-clamp measurement of ICRAC and ORAI channel activity. Cold Spring Harbor protocols, 2014(6), pp. 602-607. Cold Spring Harbor Laboratory 10.1101/pdb.top066795

Alansary, Dalia; Kilch, Tatiana; Holzmann, Christian; Peinelt, Christine; Hoth, Markus; Lis, Annette (2014). The minimal requirements to use calcium imaging to analyze ICRAC. Cold Spring Harbor protocols, 2014(6), pp. 638-642. Cold Spring Harbor Laboratory 10.1101/pdb.prot073262

Alansary, Dalia; Kilch, Tatiana; Holzmann, Christian; Peinelt, Christine; Hoth, Markus; Lis, Annette (2014). Measuring endogenous ICRAC and ORAI currents with the patch-clamp technique. Cold Spring Harbor protocols, 2014(6), pp. 630-637. Cold Spring Harbor Laboratory 10.1101/pdb.prot073254

Bürgi, Justus; Awale, Mahendra; Boss, Silvan D.; Schaer, Tifany; Marger, Fabrice; Viveros Paredes, Juan Manuel; Bertrand, Sonia; Gertsch, Jürg; Bertrand, Daniel; Reymond, Jean-Louis (2014). Discovery of Potent Positive Allosteric Modulators of the α3β2 Nicotinic Acetylcholine Receptor by a Chemical Space Walk in ChEMBL. ACS chemical neuroscience, 5(5), pp. 346-359. American Chemical Society 10.1021/cn4002297

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Gachet Otanez, Maria Salomé; Boggavarapu, Venkata Ravi Naga Rajendr; Ucurum Fotiadis, Zöhre; Gertsch, Jürg; Fotiadis, Dimitrios José (2014). Variation of the detergent-binding capacity and phospholipid content of membrane proteins when purified in different detergents. Biophysical journal, 106(8), pp. 1660-1670. Biophysical Society 10.1016/j.bpj.2014.02.024

Klauke, A.-L.; Racz, I.; Pradier, B.; Markert, A.; Zimmer, A. M.; Gertsch, J.; Zimmer, A. (2014). The cannabinoid CB2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain. European neuropsychopharmacology, 24(4), pp. 608-620. Elsevier 10.1016/j.euroneuro.2013.10.008

Franz, Marie-Christine; Simonin, Alexandre; Graeter, Stefanie; Hediger, Matthias; Kovacs, Gergely (2014). Development of the First Fluorescence Screening Assay for the SLC39A2 Zinc Transporter. Journal of biomolecular screening, 19(6), pp. 909-916. Sage 10.1177/1087057114526781

Clemençon, Benjamin; Fine, Michael; Lüscher, Benjamin; Baumann, Marc; Surbek, Daniel; Abriel, Hugues; Hediger, Matthias (2014). Expression, purification, and projection structure by single particle electron microscopy of functional human TRPM4 heterologously expressed in Xenopus laevis oocytes. Protein expression and purification, 95, pp. 169-176. Elsevier 10.1016/j.pep.2013.11.017

Huang, Xiao; Ontsouka, Edgar; Lüthi, Michael; Hediger, Matthias; Jain, Arjun; Baumann, Marc Ulrich; Surbek, Daniel; Anderle, Pascale; Albrecht, Christiane (March 2014). Screening, Identification and Preliminary Investigation of Target Transporters in Pregnancy Pathologies. Reproductive sciences, 21(3), 183A-183A. Sage

Marini, Camilla; Lüscher, Benjamin; Jörger Messerli, Marianne; Sager, Ruth; Huang, Xiao; Gertsch, Jürg; Hediger, Matthias; Albrecht, Christiane; Baumann, Marc Ulrich; Surbek, Daniel (March 2014). Placental Glucose Transporter (GLUT1) Expression in Pre-Eclampsia. Reproductive sciences, 21(3), 304A-304A. Sage

Montalbetti, Nicolas; Dalghi Gens, Marianela Gisela; Albrecht, Christiane; Hediger, Matthias (2014). Nutrient Transport in the Mammary Gland: Calcium, Trace Minerals and Water Soluble Vitamins. Journal of mammary gland biology and neoplasia, 19(1), pp. 73-90. Springer 10.1007/s10911-014-9317-9

Rosell, Albert; Meury, Marcel; Alvarez-Marimon, Elena; Costa Torres, Meritxell; Pérez-Cano, Laura; Zorzano, Antonio; Fernández-Recio, Juan; Palacín, Manuel; Fotiadis, Dimitrios José (2014). Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 111(8), pp. 2966-2971. National Academy of Sciences NAS 10.1073/pnas.1323779111

Burch, Patrick; Chicca, Andrea; Gertsch, Jürg; Gademann, Karl (2014). Functionally Optimized Neuritogenic Farinosone C Analogs: SAR-Study and Investigations on Their Mode of Action. ACS medicinal chemistry letters, 5(2), pp. 172-177. American Chemical Society 10.1021/ml400435h

Baumrucker, Craig R.; Albrecht, Christiane (2014). Preface. Journal of mammary gland biology and neoplasia, 19(1), pp. 1-2. Springer 10.1007/s10911-014-9315-y

Ontsouka, Edgar; Albrecht, Christiane (2014). Cholesterol Transport and Regulation in the Mammary Gland. Journal of mammary gland biology and neoplasia, 19(1), pp. 43-58. Springer 10.1007/s10911-014-9316-x

Montalbetti, Nicolas; Simonin, Alexandre; Dalghi Gens, Marianela Gisela; Kovacs, Gergely; Hediger, Matthias (2014). Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra. Journal of biomolecular screening, 19(6), pp. 900-908. Sage 10.1177/1087057114521663

Nicolussi, Simon; Viveros Paredes, Juan Manuel; Gachet Otanez, Maria Salomé; Rau, Mark; Flores-Soto, Mario Eduardo; Blunder, Martina; Gertsch, Jürg (2014). Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice. Pharmacological research, 80, pp. 52-65. Elsevier 10.1016/j.phrs.2013.12.010

Fuster, Daniel Guido; Alexander, R. Todd (2014). Traditional and emerging roles for the SLC9 Na(+)/H (+) exchangers. Pflügers Archiv : European journal of physiology, 466(1), pp. 61-76. Springer 10.1007/s00424-013-1408-8

Lüscher, Benjamin; Clemençon, Benjamin; Marini, Camilla; Huang, Xiao; Sager, Ruth; Jeanneret, Céline; Reymond, Jean-Louis; Albrecht, Christiane; Hediger, Matthias; Surbek, Daniel; Baumann, Marc Ulrich (January 2014). Placental Uric Acid Transport System: Glucose Transporter 9 (SLC2A9). Reproductive sciences, 21(3), 303A-303A. Sage

Abumaree, M.H.; Alahari, S.; Albrecht, C.; Aye, I.L.M.H.; Bainbridge, S.; Chauvin, S.; Clifton, V.L.; Desoye, G.; Ermini, L.; Giuffrida, D.; Graham, C.H.; Huang, Q.-T.; Kalionis, B.; Lager, S.; Leach, L.; Li, Y.; Litvack, M.L.; Nuzzo, A.M.; Moretto-Zita, M.; O'Tierney-Ginn, P.; ... (2014). IFPA Meeting 2013 Workshop Report I: Diabetes in pregnancy, maternal dyslipidemia in pregnancy, oxygen in placental development, stem cells and pregnancy pathology. Placenta, 35, S4-S9. Elsevier 10.1016/j.placenta.2013.11.010

Zhang, Jianning; Fuster, Daniel Guido; Cameron, Mary Ann; Quinones, Herny; Griffith, Carolyn; Xie, Xiao-Song; Moe, Orson W. (2014). Incomplete Distal Renal Tubular Acidosis from a Heterozygous Mutation of the V-ATPase B1 Subunit. American journal of physiology - renal physiology, 307(9), F1063-F1071. American Physiological Society 10.1152/ajprenal.00408.2014

Babiychuk, Eduard; Draeger, Annette; Wolfmeier, Heidi Annemarie; Luginbühl, Miriam (2014). Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice. Nature biotechnology, 33(1), pp. 81-88. Nature America 10.1038/nbt.3037

Schmidt, Remo; Bütikofer, Peter (2014). Autophagy in Trypanosoma brucei: amino acid requirement and regulation during different growth phases. PLoS ONE, 9(4), e93875. Public Library of Science 10.1371/journal.pone.0093875

Carta, Valentina; Pangerl, Michael; Baur, Roland; Puthenkalam, Roshan; Ernst, Margot; Trauner, Dirk; Sigel, Erwin (2014). A pentasymmetric open channel blocker for Cys-loop receptor channels. PLoS ONE, 9(9), e106688. Public Library of Science 10.1371/journal.pone.0106688

Rexhaj, Emrush; Paoloni-Giacobino, Ariane; Rimoldi, Stefano F.; Fuster, Daniel Guido; Anderegg, Manuel; Somm, Emmanuel; Bouillet, Elisa; Allemann, Yves; Sartori, Claudio; Scherrer, Urs (2013). Mice generated by in vitro fertilization exhibit vascular dysfunction and shortened life span. Journal of clinical investigation, 123(12), pp. 5052-5060. American Society for Clinical Investigation 10.1172/JCI68943

Baumann, M.; Körner, M.; Huang, X.; Wenger, F.; Surbek, D.; Albrecht, C. (2013). Placental ABCA1 and ABCG1 expression in gestational disease: pre-eclampsia affects ABCA1 levels in syncytiotrophoblasts. Placenta, 34(11), pp. 1079-1086. Elsevier 10.1016/j.placenta.2013.06.309

Holzmann, Christian; Kilch, Tatiana; Kappel, Sven; Armbrüster, Andrea; Jung, Volker; Stöckle, Michael; Bogeski, Ivan; Schwarz, Eva C; Peinelt, Christine (2013). ICRAC controls the rapid androgen response in human primary prostate epithelial cells and is altered in prostate cancer. OncoTarget, 4(11), pp. 2096-2107. Impact Journals LLC 10.18632/oncotarget.1483

Bippes, Christian A.; Ge, Lin; Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Daniel, Hannelore; Fotiadis, Dimitrios; Müller, Daniel J. (2013). Peptide transporter DtpA has two alternate conformations, one of which is promoted by inhibitor binding. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 110(42), E3978-E3986. National Academy of Sciences NAS 10.1073/pnas.1312959110

Adinolfi, Barbara; Romanini, Antonella; Vanni, Alessia; Martinotti, Enrica; Chicca, Andrea; Fogli, Stefano; Nieri, Paola (2013). Anticancer activity of anandamide in human cutaneous melanoma cells. European journal of pharmacology, 718(1-3), pp. 154-159. Elsevier 10.1016/j.ejphar.2013.08.039

Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Harder, Daniel; Schneider, Philipp; Ucurum, Zöhre; Hediger, Matthias; Fotiadis, Dimitrios (2013). Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1). PLoS ONE, 8(10), e76427. Public Library of Science 10.1371/journal.pone.0076427

Kovacs, Gergely; Montalbetti, Nicolas; Franz, Marie-Christine; Graeter, Stefanie; Simonin, Alexandre; Hediger, Matthias A. (2013). Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity. Cell calcium, 54(4), pp. 276-286. Elsevier 10.1016/j.ceca.2013.07.003

Wullschleger, Christoph W.; Gertsch, Jürg; Altmann, Karl-Heinz (2013). Synthesis and Biological Activity of 7,8,9-Trideoxy- and 7 R DesTHP-Peloruside A. Chemistry - a European journal, 19(39), pp. 13105-13111. Wiley-VCH 10.1002/chem.201301796

Baur, Roland; Gertsch, Jürg; Sigel, Erwin (2013). Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action and the binding site on the β 2 subunit of GABA A receptors? PeerJ, 1, e149. PeerJ, Ltd 10.7717/peerj.149

Huang, Xiao; Anderle, Pascale; Ontsouka, Edgar; Jain, Arjun; Surbek, Daniel; Baumann, Marc; Albrecht, Christiane (2013). Screening strategy and first results for the identification of novel membrane transporter targets in IUGR and pre-eclampsia. Placenta, 34(9), A94-A95. Elsevier 10.1016/j.placenta.2013.06.280

Marini, Camilla; Lüscher, Benjamin P.; Surbek, Daniel V.; Messerli, Marianne; Sager, Ruth; Albrecht, Christiane; Hediger, Matthias A.; Baumann, Marc (2013). Placental Glucose Transporter GLUT1 Expression in Pre-eclampsia. Placenta, 34(9), A88. Elsevier 10.1016/j.placenta.2013.06.262

Lüscher, Benjamin P.; Clemençon, Benjamin; Surbeck, Daniel V.; Huang, Xiao; Marini, Camilla; Hediger, Matthias A.; Albrecht, Christiane; Baumann, Marc (2013). Placental uric acid transport system. Placenta, 34(9), A95. Elsevier 10.1016/j.placenta.2013.06.282

Rufener, Lucien; Bedoni, Nicola; Baur, Roland; Rey, Samantha; Glauser, Dominique A.; Bouvier, Jacques; Beech, Robin; Sigel, Erwin; Puoti, Alessandro (2013). acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans. PLoS pathogens, 9(8), e1003524. Public Library of Science 10.1371/journal.ppat.1003524

Simonin, Jonathan; Jack, Thomas; Ruepp, Marc-David; Hothersall, Daniel; Connolly, Christopher; Chicca, Andrea; Gertsch, Jürg; Thompson, Andrew James; Lummis, Sarah C. R.; Lochner, Martin (August 2013). Synthesis of fluorescent probes for the study of the 5-HT3 receptor: applications in imaging and fluorescence polarization. CHIMIA, 67(7/8), p. 524. Schweizerische Chemische Gesellschaft

Ontsouka, Edgar Corneille; Huang, Xiao; Stieger, Bruno; Albrecht, Christiane (2013). Characteristics and functional relevance of apolipoprotein-A1 and cholesterol binding in mammary gland tissues and epithelial cells. PLoS ONE, 8(7), e70407. Public Library of Science 10.1371/journal.pone.0070407

Jelk, Jennifer; Gao, Ningguo; Serricchio, Mauro; Signorell, Aita; Schmidt, Remo; Bangs, James D; Acosta-Serrano, Alvaro; Lehrman, Mark A; Bütikofer, Peter; Menon, Anant K (2013). Glycoprotein biosynthesis in a eukaryote lacking the membrane protein Rft1. Journal of biological chemistry, 288(28), pp. 20616-23. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.479642

Macêdo, Juan P.; Schmidt, Remo S.; Mäser, Pascal; Rentsch, Doris; Vial, Henri J.; Sigel, Erwin; Bütikofer, Peter (2013). Characterization of choline uptake in Trypanosoma brucei procyclic and bloodstream forms. Molecular and biochemical parasitology, 190(1), pp. 16-22. Amsterdam: Elsevier 10.1016/j.molbiopara.2013.05.007

Papacleovoulou, Georgia; Abu-Hayyeh, Shadi; Nikolopoulou, Evanthia; Briz, Oscar; Owen, Bryn M.; Nikolova, Vanya; Ovadia, Caroline; Huang, Xiao; Vaarasmaki, Marja; Baumann, Marc; Jansen, Eugene; Albrecht, Christiane; Jarvelin, Marjo-Riitta; Marin, Jose J. G.; Knisely, A. S.; Williamson, Catherine (2013). Maternal cholestasis during pregnancy programs metabolic disease in offspring. Journal of clinical investigation, 123(7), pp. 3172-3181. American Society for Clinical Investigation 10.1172/JCI68927

Laedermann, Cédric; Cachemaille, Matthieu; Kirschmann, Guylène; Pertin, Marie; Gosselin, Romain-Daniel; Chang, Isabelle; Albesa, Maxime; Towne, Chris; Schneider, Bernard L.; Kellenberger, Stephan; Abriel, Hugues; Decosterd, Isabelle (2013). Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain. Journal of clinical investigation, 123(7), pp. 3002-3013. American Society for Clinical Investigation 10.1172/JCI68996

Baur, Roland; Kielar, Marie; Richter, Lars; Ernst, Margot; Ecker, Gerhard F.; Sigel, Erwin (2013). Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β 2 subunit of GABA A receptors. Journal of neurochemistry, 126(1), pp. 29-36. Wiley-Blackwell 10.1111/jnc.12270

Hofer, Alexandre; Kovacs, Gergely; Zappatini, Anna; Leuenberger, Michele; Hediger, Matthias A.; Lochner, Martin (2013). Design, synthesis and pharmacological characterization of analogs of 2-aminoethyl diphenylborinate (2-APB), a known store-operated calcium channel blocker, for inhibition of TRPV6-mediated calcium transport. Bioorganic & medicinal chemistry, 21(11), pp. 3202-3213. Elsevier 10.1016/j.bmc.2013.03.037

Donowitz, Mark; Ming Tse, C.; Fuster, Daniel Guido (2013). SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangers. Molecular aspects of medicine, 34(2-3), pp. 236-251. Elsevier 10.1016/j.mam.2012.05.001

Leonti, Marco; Cabras, Stefano; Eugenia Castellanos, Maria; Challenger, Antony; Gertsch, Jürg; Casu, Laura (2013). Bioprospecting: Evolutionary implications from a post-olmec pharmacopoeia and the relevance of widespread taxa. Journal of ethnopharmacology, 147(1), pp. 92-107. Elsevier Science Ireland 10.1016/j.jep.2013.02.012

Yang, Hsin-Ya; Charles, Roch-Philippe; Hummler, Edith; Baines, Deborah L.; Isseroff, R. Rivkah (2013). The epithelial sodium channel mediates the directionality of galvanotaxis in human keratinocytes. Journal of cell science, 126(Pt 9), pp. 1942-1951. Company of Biologists Limited 10.1242/jcs.113225

Kanai, Yoshikatsu; Clemençon, Benjamin; Simonin, Alexandre; Leuenberger, Michele; Lochner, Martin; Weisstanner, Martin; Hediger, Matthias A. (2013). The SLC1 high-affinity glutamate and neutral amino acid transporter family. Molecular aspects of medicine, 34(2-3), pp. 108-120. Elsevier 10.1016/j.mam.2013.01.001

Bürzle, Marc; Suzuki, Yoshiro; Ackermann, Daniel; Miyazaki, Hiroki; Maeda, Nobuyo; Clemençon, Benjamin; Burrier, Robert; Hediger, Matthias A. (2013). The sodium-dependent ascorbic acid transporter family SLC23. Molecular aspects of medicine, 34(2-3), pp. 436-454. Amsterdam: Elsevier 10.1016/j.mam.2012.12.002

Franz, M.-C.; Anderle, P.; Bürzle, M.; Suzuki, Y; Freeman, M. R.; Hediger, M. A.; Kovacs, G. (2013). Zinc transporters in prostate cancer. Molecular aspects of medicine, 34(2-3), pp. 735-741. Elsevier 10.1016/j.mam.2012.11.007

El-Gebali, Sara; Bentz, Susanne; Hediger, Matthias A.; Anderle, Pascale (2013). Solute carriers (SLCs) in cancer. Molecular aspects of medicine, 34(2-3), pp. 719-734. Elsevier 10.1016/j.mam.2012.12.007

Smith, David E.; Clémençon, Benjamin; Hediger, Matthias A. (2013). Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications. Molecular aspects of medicine, 34(2-3), pp. 323-336. Elsevier 10.1016/j.mam.2012.11.003

Shayakul, Chairat; Clémençon, Benjamin; Hediger, Matthias A. (2013). The urea transporter family (SLC14): physiological, pathological and structural aspects. Molecular aspects of medicine, 34(2-3), pp. 313-322. Elsevier 10.1016/j.mam.2012.12.003

Bergeron, M. J.; Clémençon, B.; Hediger, M. A.; Markovich, D. (2013). SLC13 family of Na⁺-coupled di- and tri-carboxylate/sulfate transporters. Molecular aspects of medicine, 34(2-3), pp. 299-312. Elsevier 10.1016/j.mam.2012.12.001

Montalbetti, Nicolas; Simonin, Alexandre; Kovacs, Gergely; Hediger, Matthias A. (2013). Mammalian iron transporters: Families SLC11 and SLC40. Molecular aspects of medicine, 34(2-3), pp. 270-287. Elsevier 10.1016/j.mam.2013.01.002

Hediger, Matthias A.; Clémençon, Benjamin; Burrier, Robert E.; Bruford, Elspeth A. (2013). The ABCs of membrane transporters in health and disease (SLC series): introduction. Molecular aspects of medicine, 34(2-3), pp. 95-107. Elsevier 10.1016/j.mam.2012.12.009

Fotiadis, Dimitrios; Kanai, Yoshikatsu; Palacín, Manuel (2013). The SLC3 and SLC7 families of amino acid transporters. Molecular aspects of medicine, 34(2-3), pp. 139-158. Elsevier 10.1016/j.mam.2012.10.007

Bodoy, Susanna; Fotiadis, Dimitrios; Stoeger, Claudia; Kanai, Yoshikatsu; Palacín, Manuel (2013). The small SLC43 family: facilitator system l amino acid transporters and the orphan EEG1. Molecular aspects of medicine, 34(2-3), pp. 638-645. Elsevier 10.1016/j.mam.2012.12.006

Eickel, Nina; Kaiser, Gesine; Prado, Monica; Burda, Paul-Christian; Roelli, Matthias; Stanway, Rebecca R.; Heussler, Volker (2013). Features of autophagic cell death in Plasmodium liver-stage parasites. Autophagy, 9(4), pp. 568-580. Landes Bioscience 10.4161/auto.23689

Clemençon, Benjamin; Babot, Marion; Trézéguet, Véronique (2013). The mitochondrial ADP/ATP carrier (SLC25 family): pathological implications of its dysfunction. Molecular aspects of medicine, 34(2-3), pp. 485-493. Elsevier 10.1016/j.mam.2012.05.006

Farine, Luce; Bütikofer, Peter (2013). The ins and outs of phosphatidylethanolamine synthesis in Trypanosoma brucei. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1831(3), pp. 533-542. Elsevier 10.1016/j.bbalip.2012.09.008

Carreras-Sureda, Amado; Cantero-Recasens, Gerard; Rubio-Moscardo, Fanny; Kiefer, Kerstin; Peinelt, Christine; Niemeyer, Barbara A; Valverde, Miguel A; Vicente, Rubén (2013). ORMDL3 modulates store-operated calcium entry and lymphocyte activation. Human molecular genetics, 22(3), pp. 519-530. Oxford University Press 10.1093/hmg/dds450

Serricchio, Mauro; Bütikofer, Peter (2013). Phosphatidylglycerophosphate synthase associates with a mitochondrial inner membrane complex and is essential for growth of Trypanosoma brucei. Molecular microbiology, 87(3), pp. 569-79. Oxford: Blackwell Science 10.1111/mmi.12116

Kilch, Tatiana; Alansary, Dalia; Peglow, Martin; Dörr, Kathrin; Rychkov, Grigori; Rieger, Heiko; Peinelt, Christine; Niemeyer, Barbara A (2013). Mutations of the Ca2+-sensing stromal interaction molecule STIM1 regulate Ca2+ influx by altered oligomerization of STIM1 and by destabilization of the Ca2+ channel Orai1. Journal of biological chemistry, 288(3), pp. 1653-1664. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.417246

Jefferson, Tamara; Auf dem Keller, Ulrich; Bellac, Caroline; Metz, Verena V.; Broder, Claudia; Hedrich, Jana; Ohler, Anke; Maier, Wladislaw; Magdolen, Viktor; Sterchi, Erwin-Ernst; Bond, Judith S; Jayakumar, Arumugam; Traupe, Heiko; Chalaris, Athena; Rose-John, Stefan; Pietrzik, Claus U.; Postina, Rolf; Overall, Christopher M.; Becker-Pauly, Christoph (2013). The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10. Cellular and molecular life sciences, 70(2), pp. 309-333. Springer 10.1007/s00018-012-1106-2

Mittal, Nimisha; Subramanian, Gowri; Bütikofer, Peter; Madhubala, Rentala (2013). Unique posttranslational modifications in eukaryotic translation factors and their roles in protozoan parasite viability and pathogenesis. Molecular and biochemical parasitology, 187(1), pp. 21-31. Elsevier 10.1016/j.molbiopara.2012.11.001

Costa, Meritxell; Rosell, Albert; Álvarez-Marimon, Elena; Zorzano, Antonio; Fotiadis, Dimitrios; Palacín, Manuel (2013). Expression of human heteromeric amino acid transporters in the yeast Pichia pastoris. Protein expression and purification, 87(1), pp. 35-40. Elsevier 10.1016/j.pep.2012.10.003

Fotiadis, Dimitrios; Müller, Daniel J (2013). High-resolution imaging of 2D outer membrane protein F (OmpF) crystals by atomic force microscopy. In: Schmidt-Krey, Ingeborg; Cheng, Yifan (eds.) Electron Crystallography of Soluble and Membrane Proteins. Methods in Molecular Biology: Vol. 955 (pp. 461-474). Humana Press 10.1007/978-1-62703-176-9_24

Huang, Xiao; Baumann, M; Nikitina, L; Wenger, F; Surbek, D; Körner, M; Albrecht, Christiane (2013). RNA degradation differentially affects quantitative mRNA measurements of endogenous reference genes in human placenta. Placenta, 34(7), pp. 544-7. Amsterdam: Elsevier 10.1016/j.placenta.2013.03.011

Huang, Xiao; Jain, Arjun; Baumann, Marc; Körner, Meike; Surbek, Daniel; Bütikofer, Peter; Albrecht, Christiane (2013). Increased placental phospholipid levels in pre-eclamptic pregnancies. International journal of molecular sciences, 14(2), pp. 3487-99. Basel: MDPI 10.3390/ijms14023487

Deisl, Christine; Simonin, Alexandre; Anderegg, Manuel; Albano, Giuseppe; Kovacs, Gergely; Ackermann, Daniel; Moch, Holger; Dolci, Wanda; Thorens, Bernard; Hediger, Matthias; Fuster, Daniel Guido (2013). Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 110(24), pp. 10004-10009. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1220009110

Zünd, David; Gruber, Andreas; Zavolan, Mihaela; Mühlemann, Oliver (2013). Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3′ UTRs. Nature structural & molecular biology, 20(8), pp. 936-943. New York, N.Y.: Nature Publishing Group 10.1038/nsmb.2635

Hummler, Edith; Dousse, Aline; Rieder, Audrey; Stehle, Jean-Christophe; Rubera, Isabelle; Osterheld, Maria-Chiara; Beermann, Friedrich; Frateschi, Simona; Charles, Roch-Philippe (2013). The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation. PLoS ONE, 8(2), e55796. Public Library of Science 10.1371/journal.pone.0055796

Körner, Meike; Baumann, Marc; Huang, Xiao; Surbek, Daniel; Albrecht, Christiane (2013). Associations between cholesterol blood levels, placental lipid content and expression of cholesterol transporters in healthy and diseased placentas. Placenta, 34(9), A53. Elsevier 10.1016/j.placenta.2013.06.159

Albrecht, C.; Huang, X.; Ontsouka, E. C. (2013). Cholesterol transporters in lactating and nonlactating human mammary tissue. In: Zibadi, S.; Watson, R. R.; Preedy, V. R. (eds.) Handbook of Dietary and Nutritional Aspects of Human Breast Milk. Human Health Handbooks: Vol. 5 (pp. 147-164). Wageningen: Wageningen Academic Publishers 10.3920/978-90-8686-764-6_8

Balázs, B.; Dankó, T.; Kovács, G.; Köles, L.; Hediger, M. A.; Zsembery, Á. (2013). Investigation of the inhibitory effects of the benzodiazepine derivative, 5-BDBD on P2X4 purinergic receptors by two complementary methods. Cellular physiology and biochemistry, 32(1), pp. 11-24. Karger 10.1159/000350119

Pfeiffer, Bernhard; Speck-Gisler, Sandra; Barandun, Luzi; Senft, Ursula; de Groot, Claire; Lehmann, Irène; Ganci, Walter; Gertsch, Jürg; Altmann, Karl-Heinz (2013). Total Synthesis and Configurational Assignment of the Marine Natural Product Haliclamide. The Journal of organic chemistry, 78(6), pp. 2553-2563. American Chemical Society 10.1021/jo3027643

Stanisz, Hedwig; Stark, Alexandra; Kilch, Tatiana; Schwarz, Eva C; Müller, Cornelia S L; Peinelt, Christine; Hoth, Markus; Niemeyer, Barbara A; Vogt, Thomas; Bogeski, Ivan (2012). ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes. Journal of Investigative Dermatology, 132(5), pp. 1443-1451. Nature Publishing 10.1038/jid.2011.478

Stach, Michaela; Maillard, Noélie; Kadam, Rameshwar; Kalbermatter, David; Meury, M.; Page, Malcolm; Fotiadis, Dimitrios José; Darbre, Tamis; Reymond, Jean-Louis (2012). Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini. Medicinal chemistry communications - MedChemComm, 3(1), pp. 86-89. Cambridge: Royal Society of Chemistry 10.1039/c1md00272d

Eltschinger, Sandra; Greganova, Eva; Heller, Manfred; Bütikofer, Peter; Altmann, Michael (2012). Eukaryotic translation elongation factor 1A (eEF1A) domain I from S. cerevisiae is required but not sufficient for inter-species complementation. PLoS ONE, 7(7), e42338. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0042338

Ross, Daniela; Saxena, Manisha; Altmann, Michael (2012). eIF4E is an important determinant of adhesion and pseudohyphal growth of the yeast S. cerevisiae. PLoS ONE, 7(11), e50773. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0050773

Christensen, Jon; El-Gebali, Sara; Natoli, Manuela; Sengstag, Thierry; Delorenzi, Mauro; Bentz, Susanne; Bouzourene, Hanifa; Rumbo, Martin; Felsani, Armando; Siissalo, Sanna; Hirvonen, Jouni; Vila, Maya R; Saletti, Piercarlo; Aguet, Michel; Anderle, Pascale (2012). Defining new criteria for selection of cell-based intestinal models using publicly available databases. BMC Genomics, 13, p. 274. London: BioMed Central 10.1186/1471-2164-13-274

Greganova, Eva; Bütikofer, Peter (2012). Ethanolamine phosphoglycerol attachment to eEF1A is not essential for normal growth of Trypanosoma brucei. Scientific Reports, 2, p. 254. London: Nature Publishing Group 10.1038/srep00254

Lüscher, Benjamin P; Baur, Roland; Goeldner, Maurice; Sigel, Erwin (2012). Influence of GABA(A) receptor α subunit isoforms on the benzodiazepine binding site. PLoS ONE, 7(7), e42101. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0042101

Kuhn-Nentwig, Lucia; Fedorova, Irina M; Lüscher, Benjamin P; Kopp, Lukas; Trachsel, Christian; Schaller, Johann; Vu Nguyen, Xuan Lan; Seebeck, Thomas; Streitberger, Kathrin; Nentwig, Wolfgang; Sigel, Erwin; Magazanik, Lev G (2012). A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei exhibits cytolytic activities. Journal of biological chemistry, 287(30), pp. 25640-25649. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.339051

Trachsel, Christian; Siegemund, Doreen; Kämpfer, Urs; Kopp, Lukas; Bühr, Claudia; Grossmann, Jonas; Lüthi, Christoph; Cunningham, Monica; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia; Schürch, Stefan; Schaller, Johann (2012). Multicomponent venom of the spider Cupiennius salei: a bioanalytical investigation applying different strategies. FEBS journal, 279(15), pp. 2683-2694. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2012.08650.x

Eisele, Nicole; Gennari-Moser, Carine; Albrecht, Christiane; Baumann, Marc; Surbek, Daniel; Mohaupt, Markus (2012). Does Aldosterone participate in placental angiogenesis via PLGF? Pregnancy hypertension, 2(3), p. 245. Amsterdam: Elsevier 10.1016/j.preghy.2012.04.121

Körner, M; Wenger, F; NIkitina, L; Baumann, M; Surbek, D; Albrecht, C (2012). PP141. The lipid transporters ABCA1 and ABCG1 are differentially expressed in preeclamptic and IUGR placentas. Pregnancy hypertension, 2(3), pp. 315-316. Elsevier 10.1016/j.preghy.2012.04.252

Gertsch, Jürg; Viveros Paredes, Juan Manuel; Taylor, Peter (2011). Plant immunostimulants-Scientific paradigm or myth? Journal of ethnopharmacology, 136(3), pp. 385-391. Shannon: Elsevier Science Ireland 10.1016/j.jep.2010.06.044

Landowski, Christopher P; Bolanz, Katrin A; Suzuki, Yoshiro; Hediger, Matthias A (2011). Chemical inhibitors of the calcium entry channel TRPV6. Pharmaceutical research, 28(2), pp. 322-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s11095-010-0249-9

Lottaz, Daniel; Maurer, Christoph A; Noël, Agnès; Blacher, Silvia; Huguenin, Maya; Nievergelt, Alexandra; Niggli, Verena; Kern, Alexander; Müller, Stefan; Seibold, Frank; Friess, Helmut; Becker-Pauly, Christoph; Stöcker, Walter; Sterchi, Erwin E (2011). Enhanced activity of meprin-?, a pro-migratory and pro-angiogenic protease, in colorectal cancer. PLoS ONE, 6(11), e26450. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026450

Patel, Dipesh C; Albrecht, Christiane; Pavitt, Darrell; Paul, Vijay; Pourreyron, Celine; Newman, Simon P; Godsland, Ian F; Valabhji, Jonathan; Johnston, Desmond G (2011). Type 2 diabetes is associated with reduced ATP-binding cassette transporter A1 gene expression, protein and function. PLoS ONE, 6(7), e22142. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022142

Bergeron, Marc J.; Boggavarapu, Rajendra; Meury, Marcel; Ucurum, Zöhre; Caron, Luc; Isenring, Paul; Hediger, Matthias A.; Fotiadis, Dimitrios (2011). Frog oocytes to unveil the structure and supramolecular organization of human transport proteins. PLoS ONE, 6(7), e21901. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0021901

Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2011). Structure determination of channel and transport proteins by high-resolution microscopy techniques. Biological chemistry, 392(1-2), pp. 143-50. Berlin: Walter de Gruyter 10.1515/BC.2011.004

Lis, Annette; Zierler, Susanna; Peinelt, Christine; Fleig, Andrea; Penner, Reinhold (2010). A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. Journal of general physiology, 136(6), pp. 673-686. Rockefeller University Press 10.1085/jgp.201010484

Bogeski, Ivan; Al-Ansary, Dalia; Qu, Bin; Niemeyer, Barbara A; Hoth, Markus; Peinelt, Christine (2010). Pharmacology of ORAI channels as a tool to understand their physiological functions. Expert review of clinical pharmacology, 3(3), pp. 291-303. Taylor & Francis 10.1586/ecp.10.23

Bogeski, Ivan; Kummerow, Carsten; Al-Ansary, Dalia; Schwarz, Eva C; Koehler, Richard; Kozai, Daisuke; Takahashi, Nobuaki; Peinelt, Christine; Griesemer, Desiree; Bozem, Monika; Mori, Yasuo; Hoth, Markus; Niemeyer, Barbara A (2010). Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Science signaling, 3(115), ra24. American Association for the Advancement of Science 10.1126/scisignal.2000672

Hofstetter, Willy; Siegrist, Mark; Simonin, Alexandre; Bonny, Olivier; Fuster, Daniel G (2010). Sodium/hydrogen exchanger NHA2 in osteoclasts: subcellular localization and role in vitro and in vivo. Bone, 47(2), pp. 331-340. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.605

Simonin, Alexandre; Fuster, Daniel Guido (2010). Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and function. Journal of biological chemistry, 285(49), pp. 38293-38303. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.115089

Erdélyi, Máté; Navarro-Vázquez, Armando; Pfeiffer, Bernhard; Kuzniewski, Christian N; Felser, Andrea; Widmer, Toni; Gertsch, Jürg; Pera, Benet; Díaz, José Fernando; Altmann, Karl-Heinz; Carlomagno, Teresa (2010). The binding mode of side chain- and C3-modified epothilones to tubulin. ChemMedChem, 5(6), pp. 911-920. Weinheim: Wiley-VCH 10.1002/cmdc.201000050

Leonti, Marco; Casu, Laura; Gertsch, Jürg; Bonsignore, Leonardo; Floris, Costantino; Casu, Mariano; Cottiglia, Filippo (2010). A pterocarpan from the seeds of Bituminaria morisiana. Journal of natural medicines, 64(3), pp. 354-7. Tōkyō: Springer 10.1007/s11418-010-0408-7

Shwe, Htay Htay; Aye, Mye; Sein, Myint Myint; Htay, Khin Than; Kreitmeier, Peter; Gertsch, Jürg; Reiser, Oliver; Heilmann, Jörg (2010). Cytotoxic steroidal saponins from the rhizomes of Tacca integrifolia. Chemistry & Biodiversity, 7(3), pp. 610-22. Zürich: Verlag Helvetica Chimica Acta

Greganova, E; Heller, M; Bütikofer, P (2010). A structural domain mediates attachment of ethanolamine phosphoglycerol to eukaryotic elongation factor 1A in Trypanosoma brucei. PLoS ONE, 5(3), e9486. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0009486

Kempna, Petra; Ricciarelli, Roberta; Azzi, Angelo; Zingg, Jean-Marc (2010). Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene. Molecular biology reports, 37(7), pp. 3503-3508. Springer 10.1007/s11033-009-9943-2

Peinelt, Christine; Beck, Andreas; Monteilh-Zoller, Mahealani K; Penner, Reinhold; Fleig, Andrea (2009). IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). Cell calcium, 45(4), pp. 326-330. Elsevier 10.1016/j.ceca.2008.12.001

Shedova, E; Albrecht, C; Zverlov, V.V.; Schwarz, W.H. (2009). Stimulation of bacterial DNA transformation by cattle saliva: implications for using genetically modified plants in animal feed. World journal of microbiology & biotechnology, 3(25), 457-463 [7 page(s) (article)] (3/4 p.). Oxford: Springer 10.1007/s11274-008-9910-4

Signorell, Aita; Gluenz, Eva; Rettig, Jochen; Schneider, André; Shaw, Michael; Gull, Keith; Bütikofer, Peter (2009). Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei. Molecular microbiology, 72(4), pp. 1068-79. Oxford: Blackwell Science 10.1111/j.1365-2958.2009.06713.x

Vassella, Erik; Oberle, Michael; Urwyler, Simon; Renggli, Christina Kunz; Studer, Erwin; Hemphill, Andrew; Fragoso, Cristina; Bütikofer, Peter; Brun, Reto; Roditi, Isabel (2009). Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission by tsetse. PLoS ONE, 4(2), e4493. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0004493

Wächter, Regula; Masarik, Lukas; Bürzle, Marc; Mallik, Ajit; von Mandach, Ursula (2009). Differential expression and activity of 11beta-hydroxysteroid dehydrogenase in human placenta and fetal membranes from pregnancies with intrauterine growth restriction. Fetal diagnosis and therapy, 25(3), pp. 328-35. Basel: Karger 10.1159/000235879

Guertler, Patrick; Paul, Vijay; Albrecht, Christiane; Meyer, Heinrich H D (2009). Sensitive and highly specific quantitative real-time PCR and ELISA for recording a potential transfer of novel DNA and Cry1Ab protein from feed into bovine milk. Analytical and bioanalytical chemistry, 393(6-7), pp. 1629-38. Heidelberg: Springer 10.1007/s00216-009-2667-2

Peinelt, Christine; Lis, Annette; Beck, Andreas; Fleig, Andrea; Penner, Reinhold (2008). 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. Journal of physiology, 586(13), pp. 3061-3073. Wiley-Blackwell 10.1113/jphysiol.2008.151365

Parvez, Suhel; Beck, Andreas; Peinelt, Christine; Soboloff, Jonathan; Lis, Annette; Monteilh-Zoller, Mahealani; Gill, Donald L; Fleig, Andrea; Penner, Reinhold (2008). STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation. FASEB journal, 22(3), pp. 752-761. Federation of American Societies for Experimental Biology 10.1096/fj.07-9449com

Farke, Carolin; Meyer, Heinrich H D; Bruckmaier, Rupert M; Albrecht, Christiane (2008). Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue. Journal of dairy research, 75(4), pp. 406-14. London: Cambridge University Press 10.1017/S002202990800335X

Gürtler, P; Lutz, B; Kühn, R; Meyer, H.H.D.; Albrecht, C (2008). Fate of recombinant DNA and Cry1Ab protein after ingestion and dispersal of genetically modified maize in comparison to rapeseed by fallow deer (Dama dama). European journal of wildlife research, 54(2008), pp. 36-43. Berlin: Springer-Verlag 10.1007/s10344-007-0104-4

Bosshart, P.D.; Casagrande, F; Frederix, P.L.T.M.; Ratera, M; Bippes, C.A.; Müller, D.J.; Palacin, M; Engel, A; Fotiadis, D (2008). High-throughput single-molecule force spectroscopy for membrane proteins. Nanotechnology, 19(38), p. 384014. Bristol, UK: Institute of Physics Publishing IOP 10.1088/0957-4484/19/38/384014

Oneda, Beatrice; Lods, Nadège; Lottaz, Daniel; Becker-Pauly, Christoph; Stöcker, Walter; Pippin, Jeffrey; Huguenin, Maya; Ambort, Daniel; Marti, Hans-Peter; Sterchi, Erwin E (2008). Metalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis. PLoS ONE, 3(5), e2278. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0002278

Huguenin, Maya; Müller, Eliane J; Trachsel-Rösmann, Sandra; Oneda, Beatrice; Ambort, Daniel; Sterchi, Erwin E; Lottaz, Daniel (2008). The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion. PLoS ONE, 3(5), e2153. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0002153

Bergeron, M; Simonin, A; Bürzle, M; Hediger, M (2008). Inherited epithelial transporter disorders-an overview. Journal of inherited metabolic disease, 31(2), pp. 178-187. Lancaster, UK: Springer Netherlands 10.1007/s10545-008-0861-6

Suzuki, Yoshiro; Pasch, Andreas; Bonny, Olivier; Mohaupt, Markus G; Hediger, Matthias A; Frey, Felix J (2008). Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation. Human molecular genetics, 17(11), pp. 1613-8. Oxford: Oxford University Press 10.1093/hmg/ddn048

Benn, Bryan S; Ajibade, Dare; Porta, Angela; Dhawan, Puneet; Hediger, Matthias; Peng, Ji-Bin; Jiang, Yi; Oh, Goo Taeg; Jeung, Eui-Bae; Lieben, Liesbet; Bouillon, Roger; Carmeliet, Geert; Christakos, Sylvia (2008). Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology, 149(6), pp. 3196-205. Chevy Chase, Md.: Endocrine Society 10.1210/en.2007-1655

Lis, Annette; Peinelt, Christine; Beck, Andreas; Parvez, Suhel; Monteilh-Zoller, Mahealani; Fleig, Andrea; Penner, Reinhold (2007). CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties. Current Biology, 17(9), pp. 794-800. Cell Press 10.1016/j.cub.2007.03.065

Kyriakou, Theodosios; Pontefract, David E; Viturro, Enrique; Hodgkinson, Conrad P; Laxton, Ross C; Bogari, Neda; Cooper, George; Davies, Michael; Giblett, Joel; Day, Ian N M; Simpson, Iain A; Albrecht, Christiane; Ye, Shu (2007). Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients. Human molecular genetics, 16(12), pp. 1412-22. Oxford: Oxford University Press 10.1093/hmg/ddm091

Schütte, Andre; Lottaz, Daniel; Sterchi, Erwin E; Stöcker, Walter; Becker-Pauly, Christoph (2007). Two alpha subunits and one beta subunit of meprin zinc-endopeptidases are differentially expressed in the zebrafish Danio rerio. Biological chemistry, 388(5), pp. 523-31. Berlin: Walter de Gruyter 10.1515/BC.2007.060

Lottaz, Daniel; Buri, Caroline; Monteleone, Giovanni; Rösmann, Sandra; Macdonald, Thomas T; Sanderson, Ian R; Sterchi, Erwin E (2007). Compartmentalised expression of meprin in small intestinal mucosa: enhanced expression in lamina propria in coeliac disease. Biological chemistry, 388(3), pp. 337-41. Berlin: Walter de Gruyter 10.1515/BC.2007.038

Vig, Monika; Beck, Andreas; Billingsley, James M; Lis, Annette; Parvez, Suhel; Peinelt, Christine; Koomoa, Dana L; Soboloff, Jonathan; Gill, Donald L; Fleig, Andrea; Kinet, Jean-Pierre; Penner, Reinhold (2006). CRACM1 multimers form the ion-selective pore of the CRAC channel. Current Biology, 16(20), pp. 2073-2079. Cell Press 10.1016/j.cub.2006.08.085

Peinelt, Christine; Vig, Monika; Koomoa, Dana L; Beck, Andreas; Nadler, Monica J S; Koblan-Huberson, Murielle; Lis, Annette; Fleig, Andrea; Penner, Reinhold; Kinet, Jean-Pierre (2006). Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nature cell biology, 8(7), pp. 771-773. Nature Publishing Group 10.1038/ncb1435

Vig, M; Peinelt, Christine; Beck, A; Koomoa, D L; Rabah, D; Koblan-Huberson, M; Kraft, S; Turner, H; Fleig, A; Penner, R; Kinet, J-P (2006). CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Science, 312(5777), pp. 1220-1223. American Association for the Advancement of Science 10.1126/science.1127883

Konrad, Martin; Schaller, André; Seelow, Dominik; Pandey, Amit Vikram; Waldegger, Siegfried; Lesslauer, Annegret; Vitzthum, Helga; Suzuki, Yoshiro; Luk, John M; Becker, Christian; Schlingmann, Karl P; Schmid, Marcel; Rodriguez-Soriano, Juan; Ariceta, Gema; Cano, Francisco; Enriquez, Ricardo; Juppner, Harald; Bakkaloglu, Sevcan A; Hediger, Matthias A; Gallati, Sabina; ... (2006). Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement. American journal of human genetics, 79(5), pp. 949-57. New York, N.Y.: Cell Press 10.1086/508617

Berger, Urs V; Hediger, Matthias A (2006). Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs. Anatomy and embryology, 211(6), pp. 595-606. Berlin: Springer-Verlag 10.1007/s00429-006-0109-x

Zingg, Jean-Marc (2006). Modulation of signal transduction by vitamin E. Molecular aspects of medicine, 28(5-6), pp. 481-506. Amsterdam: Elsevier 10.1016/j.mam.2006.12.009

Peinelt, Christine; Apell, Hans-Jürgen (2005). Kinetics of Ca2+ binding to the SR Ca-ATPase in the E1 state. Biophysical journal, 89(4), pp. 2427-2433. Biophysical Society 10.1529/biophysj.105.068411

Peinelt, Christine; Apell, Hans-Jürgen (2004). Time-resolved charge movements in the sarcoplasmatic reticulum Ca-ATPase. Biophysical journal, 86(2), pp. 815-824. Biophysical Society 10.1016/S0006-3495(04)74157-0

Dauchet, Luc; Ferrières, Jean; Arveiler, Dominique; Yarnell, John W.; Gey, Fred; Ducimetière, Pierre; Ruidavets, Jean-Bernard; Haas, Bernadette; Evans, Alun; Bingham, Annie; Amouyel, Philippe; Dallongeville, Jean (2004). Frequency of fruit and vegetable consumption and coronary heart disease in France and Northern Ireland: the PRIME study. British journal of nutrition, 92(6), pp. 963-972. Cambridge University Press 10.1079/BJN20041286

Azzi, Angelo (2004). The role of α-tocopherol inpreventing disease. European Journal of Nutrition, 43(S1), i18-i25. Springer-Verlag 10.1007/s00394-004-1105-7

Peinelt, Christine; Apell, Hans-Jürgen (2003). Time-resolved partial reactions of the SR Ca-ATPase investigated with a fluorescent styryl dye. Annals of the New York Academy of Sciences, 986, pp. 325-326. Blackwell

Peinelt, Christine; Apell, Hans-Jürgen (2002). Kinetics of the Ca(2+), H(+), and Mg(2+) interaction with the ion-binding sites of the SR Ca-ATPase. Biophysical journal, 82(1 Pt 1), pp. 170-181. Biophysical Society 10.1016/S0006-3495(02)75384-8

Lottaz, Daniel; Hahn, Dagmar; Müller, Stefan; Müller, Christoph; Sterchi, Erwin E (1999). Secretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunits. European journal of biochemistry, 259(1-2), pp. 496-504. FEBS Press 10.1046/j.1432-1327.1999.00071.x

Harmon, D.L.; Woodside, J.V.; Yarnell, J.W.G.; Mcmaster, D.; Young, I.S.; Mccrum, E.E.; Gey, K.F.; Whitehead, A.S.; Evans, A.E. (1996). The common ‘thermolabile’ variant of methylene tetrahydrofolate reductase is a major determinant of mild hyperhomocysteinaemia. QJM - an international journal of medicine, 89(8), pp. 571-578. Oxford University Press 10.1093/qjmed/89.8.571

Owttrim, George W; Mandel, Therese; Trachsel, Hans; Thomas, Adri AM; Kuhlemeier, Cris (1994). Characterization of the tobacco eIF-4A gene family. Plant molecular biology, 26(6), pp. 1747-1757. Springer 10.1007/BF00019489

Gey, K F (1993). Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease. British medical bulletin, 49(3), pp. 679-699. Oxford University Press 10.1093/oxfordjournals.bmb.a072640

Longnecker, Matthew P.; Martin-Moreno, Jose-Maria; Knekt, Paul; Nomura, Abraham M. Y.; Schober, Susan E.; Stähelin, Hannes B.; Wald, Nicholas J.; Gey, K. Fred; Willett, Walter C. (1992). Serum α-Tocopherol Concentration in Relation to Subsequent Colorectal Cancer: Pooled Data From Five Cohorts. Journal of the National Cancer Institute JNCI, 84(6), pp. 430-435. Oxford University Press 10.1093/jnci/84.6.430

This list was generated on Mon Dec 23 02:19:52 2024 CET.

Export as	RSS