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Sokollik, Christiane; Simon, Hans-Uwe (2017). Physiologie der eosinophilen Granulozyten. Therapeutische Umschau, 74(6), pp. 291-296. Hogrefe 10.1024/0040-5930/a000917

Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Spirk, David (2016). Rivaroxaban for the treatment of venous thromboembolism. The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 116(3), pp. 472-479. Schattauer 10.1160/TH16-03-0209

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2016). The Role of Autophagy in Cancer and Chemotherapy. In: Hayat, M. (ed.) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Human Diseases: Vol. 8 (pp. 253-265). Academic Press 10.1016/B978-0-12-802937-4.00014-4

He, Zhaoyue; Agostini, Massimiliano; Liu, He; Melino, Gerry; Simon, Hans-Uwe (2015). p73 regulates basal and starvation-induced liver metabolism in vivo. OncoTarget, 6(32), pp. 33178-33190. Impact Journals LLC 10.18632/oncotarget.5090

Boyman, O; Kaegi, C; Akdis, M; Bavbek, S; Bossios, A; Chatzipetrou, A; Eiwegger, T; Firinu, D; Harr, T; Knol, E; Matucci, A; Palomares, O; Schmidt-Weber, C; Simon, Hans-Uwe; Steiner, U C; Vultaggio, A; Akdis, C A; Spertini, F (2015). EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders. Allergy, 70(7), pp. 727-754. Wiley-Blackwell 10.1111/all.12616

Hurrell, Benjamin P; Schuster, Steffen; Grün, Eva; Coutaz, Manuel; Williams, Roderick A; Held, Werner; Malissen, Bernard; Malissen, Marie; Yousefi, Shida; Simon, Hans-Uwe; Müller, Andreas J; Tacchini-Cottier, Fabienne (2015). Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. PLoS pathogens, 11(5), e1004929. Public Library of Science 10.1371/journal.ppat.1004929

Galluzzi, Lorenzo; Pietrocola, Federico; Bravo-San Pedro, José Manuel; Amaravadi, Ravi K; Baehrecke, Eric H; Cecconi, Francesco; Codogno, Patrice; Debnath, Jayanta; Gewirtz, David A; Karantza, Vassiliki; Kimmelman, Alec; Kumar, Sharad; Levine, Beth; Maiuri, Maria Chiara; Martin, Seamus J; Penninger, Josef; Piacentini, Mauro; Rubinsztein, David C; Simon, Hans-Uwe; Simonsen, Anne; ... (2015). Autophagy in malignant transformation and cancer progression. EMBO journal, 34(7), pp. 856-880. Nature Publishing Group 10.15252/embj.201490784

Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570

Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Eveline; Schmid, Ines; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S and Simon, Hans-Uwe (2015). Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular cell, 57(6), pp. 1011-1021. Cell Press 10.1016/j.molcel.2015.01.026

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Targeting disease by immunomodulation. Cell death and differentiation, 22(2), pp. 185-186. Nature Publishing Group 10.1038/cdd.2014.166

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2015). Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. Journal of molecular medicine JMM, 93(2), pp. 159-164. Springer 10.1007/s00109-014-1241-3

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Radonjic-Hoesli, Susanne; Valent, Peter; Klion, Amy D; Wechsler, Michael E; Simon, Hans-Uwe (2015). Novel targeted therapies for eosinophil-associated diseases and allergy. Annual review of pharmacology and toxicology, 55, pp. 633-656. Annual Reviews Inc. 10.1146/annurev-pharmtox-010814-124407

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

Kerr, Jacqueline; Quinti, Isabella; Eibl, Martha; Chapel, Helen; Späth, Peter Julius; Sewell, W A Carrock; Salama, Abdulgabar; van Schaik, Ivo N; Kuijpers, Taco W; Peter, Hans-Hartmut (2014). Is dosing of therapeutic immunoglobulins optimal? A review of a three-decade long debate in europe. Frontiers in immunology, 5(629), p. 629. Frontiers Research Foundation 10.3389/fimmu.2014.00629

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Späth, Peter Julius (2014). Report on Congress Highlights 2013. Congress Report 2013.

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2013). Glucocorticoids in autoimmune bullous diseases: are neutrophils the key cellular target? Journal of Investigative Dermatology, 133(10), pp. 2314-2315. Nature Publishing 10.1038/jid.2013.205

Krudewig, J; Baumann, U; Bernuth von, H; Borte, M; Burkhard-Meier, U; Dueckers, G; Foerster-Waldl, E; Franke, K; Habermehl, P; Hönig, M; Kern, W; Kösters, K; Kugel, K; Lehrnbecher, T; Liese, J; Marks, R; Müller, G A; Müller, R; Nadal, D; Peter, H-H; ... (2012). [Interdisciplinary AWMF guideline for the treatment of primary antibody deficiencies]. Klinische Pädiatrie, 224(6), pp. 404-15. Stuttgart: Thieme 10.1055/s-0032-1323837

Simon, Hans-Uwe (2009). Regulation of cell survival. In: Adkinson, N. Franklin; Busse, William W; Bochner, Bruce S; Holgate, Stephen T; Simons, Estelle R; Lemanske, Robert F (eds.) Middleton's Allergy: Principles and Practice, 7th Edition (pp. 413-421). Mosby

Colombo, M.I.; Simon, H.U. (2009). Autophagy. In: Encyclopedia of Life Sciences (ELS). Chichester: J. Wiley & Sons

Yes

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Schwalm, Stephanie; Beyer, Sandra; Hafizi, Redona; Trautmann, Sandra; Geisslinger, Gerd; Adams, David R; Pyne, Susan; Pyne, Nigel; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2021). Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis. Cellular signalling, 79(109881), p. 109881. Elsevier 10.1016/j.cellsig.2020.109881

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. (In Press). Blood American Society of Hematology 10.1182/blood.2020010208

Leroux, Cédric; Konstantinidou, Georgia (2021). Targeted Therapies for Pancreatic Cancer: Overview of Current Treatments and New Opportunities for Personalized Oncology. Cancers, 13(4) MDPI AG 10.3390/cancers13040799

Psarra, Anastasia; Theodoropoulou, Maria A; Erhardt, Martin; Mertiri, Marina; Mantzourani, Christiana; Vasilakaki, Sofia; Magrioti, Victoria; Huwiler, Andrea; Kokotos, George (2021). α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E2 (PGE2) in Rat Mesangial Cells. Biomolecules, 11(2) MDPI 10.3390/biom11020275

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Biedermann, Luc; Holbreich, Mark; Atkins, Dan; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Hirano, Ikuo; Gonsalves, Nirmala; Greuter, Thomas; Katzka, David A; De Rooij, Willemijn; Safroneeva, Ekaterina; Schoepfer, Alain; Schreiner, Philipp; Simon, Dagmar; Simon, Hans Uwe; Warners, Marijn; Bredenoord, Albert-Jan; Straumann, Alex (2021). Food-induced Immediate Response of the Esophagus - a newly identified Syndrome in Patients with Eosinophilic Esophagitis. Allergy, 76(1), pp. 339-347. Wiley-Blackwell 10.1111/all.14495

Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Wang, Xiaoliang; Avsec, Damjan; Obreza, Aleš; Yousefi, Shida; Mlinarič-Raščan, Irena; Simon, Hans-Uwe (2021). A Putative Serine Protease is Required to Initiate the RIPK3-MLKL-Mediated Necroptotic Death Pathway in Neutrophils. Frontiers in Pharmacology, 11, p. 614928. Frontiers 10.3389/fphar.2020.614928

Cummings, Richard D; von Gunten, Stephan (2021). Targeting the Laminated Layer of Echinococcus multilocularis as a Potential Therapeutic Strategy. Pharmacology, 106(1-2), pp. 1-2. Karger 10.1159/000512769

von Gunten, Stephan; Simon, Hans-Uwe (2020). Linking glucocorticoid-induced osteoporosis to osteoimmunology. Cell death & disease, 11(12), p. 1026. Nature Publishing Group 10.1038/s41419-020-03250-x

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706

Yu, Yi; Ladeiras, Diogo; Xiong, Yuyan; Frias Boligan, Kayluz; Liang, Xiujie; von Gunten, Stephan; Hunger, Robert E.; Ming, Xiu-Fen; Yang, Zhihong (2020). Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. Journal of cellular physiology, 235(12), pp. 9997-10011. Wiley 10.1002/jcp.29814

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Brandl, Fabian; Busslinger, Sarah; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2020). Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life. Journal of controlled release, 327, pp. 186-197. Elsevier 10.1016/j.jconrel.2020.08.004

Wahn, V; Aberer, W; Aygören-Pürsün, E; Bork, K; Eberl, W; Faßhauer, M; Krüger, R; Magerl, M; Martinez-Saguer, I; Späth, P.; Staubach-Renz, P; Weber-Chrysochoou, C (2020). Hereditary angioedema in children and adolescents - A consensus update on therapeutic strategies for German-speaking countries. Pediatric allergy and immunology, 31(8), pp. 974-989. Wiley-Blackwell 10.1111/pai.13309

Saliakoura, Maria; Rossi, Sebastiano Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Dalakas, Marinos C; Alexopoulos, Harry; Späth, Peter J (2020). Complement in neurological disorders and emerging complement-targeted therapeutics. Nature reviews. Neurology, 16(11), pp. 601-617. Nature Publishing Group 10.1038/s41582-020-0400-0

Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2020). Corrigendum to "Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms" [Biochim. Biophys. Acta Mol. Basis Dis. 2019 Apr 1;1865(4):774-781]. Biochimica et biophysica acta - molecular basis of disease, 1866(10), p. 165892. Elsevier 10.1016/j.bbadis.2020.165892

Schreiner, Philipp; Meissgeier, Silas; Safroneeva, Ekaterina; Greuter, Thomas; Rogler, Gerhard; Schoepfer, Alain; Simon, Dagmar; Simon, Hans-Uwe; Biedermann, Luc; Straumann, Alex (2020). Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology, 18(11), pp. 2456-2462. Elsevier 10.1016/j.cgh.2019.11.057

Wandrer, Franziska; Frangež, Živa; Liebig, Stephanie; John, Katharina; Vondran, Florian; Wedemeyer, Heiner; Veltmann, Christian; Pfeffer, Tobias J; Shibolet, Oren; Schulze-Osthoff, Klaus; Simon, Hans-Uwe; Bantel, Heike (2020). Autophagy alleviates amiodarone-induced hepatotoxicity. Archives of toxicology, 94(10), pp. 3527-3539. Springer-Verlag 10.1007/s00204-020-02837-9

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107

Luetscher, Ralph N D; McKitrick, Tanya R; Gao, Chao; Mehta, Akul Y; McQuillan, Alyssa M; Kardish, Robert; Frias Boligan, Kayluz; Song, Xuezheng; Lu, Lenette; Heimburg-Molinaro, Jamie; von Gunten, Stephan; Alter, Galit; Cummings, Richard D (2020). Unique repertoire of anti-carbohydrate antibodies in individual human serum. Scientific reports, 10(1), p. 15436. Springer Nature 10.1038/s41598-020-71967-y

Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113

von Gunten, Stephan (2020). Inflamm-Aging: Arginase-II as Stage Setter in Age-Related Adipose Tissue Inflammation. Pharmacology, 105(9-10), pp. 489-490. Karger 10.1159/000510515

Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463

Sebastian, Tim; Barco, Stefano; Engelberger, Rolf P; Spirk, David; Schindewolf, Marc; Baumann, Frederic; Baumgartner, Iris; Kucher, Nils (2020). Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. European journal of vascular and endovascular surgery EJVES, 60(3), pp. 443-450. Elsevier 10.1016/j.ejvs.2020.05.011

Naim, Samara; Kaufmann, Thomas (2020). The Multifaceted Roles of the BCLL-2 Family Member BOK. Frontiers in cell and developmental biology, 8 Frontiers 10.3389/fcell.2020.574338

Simon, Hans-Uwe; Karaulov, Alexander V; Bachmann, Martin F. (2020). Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection. International archives of allergy and immunology, 181(8), pp. 624-628. Karger 10.1159/000509368

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007

Stepanovska, Bisera; Huwiler, Andrea (2020). Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases. Pharmacological research, 154, p. 104170. Elsevier 10.1016/j.phrs.2019.02.009

Saliakoura, Maria; Reynoso-Moreno, Inés; Pozzato, Chiara; Rossi Sebastiano, Matteo; Galié, Mirco; Gertsch, Jürg; Konstantinidou, Georgia (2020). The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Oncogene, 39(14), pp. 2948-2960. Springer Nature 10.1038/s41388-020-1196-5

Maurer, Marcus; Eyerich, Kilian; Eyerich, Stefanie; Ferrer, Marta; Gutermuth, Jan; Hartmann, Karin; Jakob, Thilo; Kapp, Alexander; Kolkhir, Pavel; Larenas-Linnemann, Désirée; Park, Hae-Sim; Pejler, Gunnar; Sánchez-Borges, Mario; Schäkel, Knut; Simon, Dagmar; Simon, Hans-Uwe; Weller, Karsten; Zuberbier, Torsten; Metz, Martin (2020). Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(5), pp. 321-333. Karger 10.1159/000507218

Ramadori, Giorgio; Ioris, Rafael M; Villanyi, Zoltan; Firnkes, Raquel; Panasenko, Olesya O; Allen, George; Konstantinidou, Georgia; Aras, Ebru; Brenachot, Xavier; Biscotti, Tommasina; Charollais, Anne; Luchetti, Michele; Bezrukov, Fedor; Santinelli, Alfredo; Samad, Muntaha; Baldi, Pierre; Collart, Martine A; Coppari, Roberto (2020). FKBP10 Regulates Protein Translation to Sustain Lung Cancer Growth. Cell reports, 30(11), pp. 3851-863. Cell Press 10.1016/j.celrep.2020.02.082

Müller, Ines; Strozyk, Elwira; Schindler, Sebastian; Beissert, Stefan; Oo, Htoo Zarni; Sauter, Thomas; Lucarelli, Philippe; Raeth, Sebastian; Hausser, Angelika; Al Nakouzi, Nader; Fazli, Ladan; Gleave, Martin E; Liu, He; Simon, Hans-Uwe; Walczak, Henning; Green, Douglas R; Bartek, Jiri; Daugaard, Mads; Kulms, Dagmar (2020). Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. Molecular cell, 77(5), 970-984.e7. Cell Press 10.1016/j.molcel.2019.12.023

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Human IgA binds a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.20181635

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Correction: Human IgA bind a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.2018163501152020c

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Grafinger, Katharina Elisabeth; Liechti, Matthias E; Liakoni, Evangelia (2020). Clinical value of analytical testing in patients presenting with New Psychoactive Substances intoxication. British journal of clinical pharmacology, 86(3), pp. 429-436. Wiley-Blackwell 10.1111/bcp.14115

Boligan, Kayluz F.; Oechtering, Johanna; Keller, Christian W; Peschke, Benjamin; Rieben, Robert; Bovin, Nicolai; Kappos, Ludwig; Cummings, Richard D; Kuhle, Jens; von Gunten, Stephan; Lünemann, Jan D (2020). Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS. Neurology: Neuroimmunology and Neuroinflammation, 7(2) Wolters Kluwer Health 10.1212/NXI.0000000000000676

Spinetti, Thibaud; Meisel, Christian; von Gunten, Stephan; Schefold, Joerg C. (2020). Immune biomarker-based enrichment in sepsis trials. Critical care, 24(1), p. 58. BioMed Central 10.1186/s13054-020-2774-1

Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041396

Stepanovska, Bisera; Lange, Antonia I; Schwalm, Stephanie; Pfeilschifter, Josef; Coldewey, Sina M; Huwiler, Andrea (2020). Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041240

Zanchin, Christian; Ueki, Yasushi; Losdat, Sylvain; Fahrni, Gregor; Daemen, Joost; Ondracek, Anna S; Häner, Jonas D.; Stortecky, Stefan; Otsuka, Tatsuhiko; Siontis, George C.M.; Rigamonti, Fabio; Radu, Maria; Spirk, David; Kaiser, Christoph; Engstrom, Thomas; Lang, Irene; Koskinas, Konstantinos C.; Räber, Lorenz (2020). In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study. (In Press). European heart journal - cardiovascular imaging Oxford University Press 10.1093/ehjci/jez318

Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Owsley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2020). Correction: TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell death & disease, 11(1), p. 56. Springer Nature 10.1038/s41419-020-2261-2

He, Zhaoyue; Liu, He; Moch, Holger; Simon, Hans-Uwe (2020). Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Scientific reports, 10(1), p. 720. Springer Nature 10.1038/s41598-020-57670-y

Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Simon, Dagmar; Simon, Hans-Uwe (2020). Relationship of skin barrier breakdown and eosinophilic esophagitis. Journal of allergy and clinical immunology, 145(1), 90-92.e1. Elsevier 10.1016/j.jaci.2019.11.005

Markov, Nikita; Simon, Hans-Uwe (2020). IL-37: A new player in the chronic rhinosinusitis arena. The Journal of allergy and clinical immunology, 145(1), pp. 105-107. Elsevier 10.1016/j.jaci.2019.10.018

Surmiak, Marcin; Gielicz, Anna; Stojkov, Darko; Szatanek, Rafał; Wawrzycka-Adamczyk, Katarzyna; Yousefi, Shida; Simon, Hans-Uwe; Sanak, Marek (2020). LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis. Journal of lipid research, 61(1), pp. 1-9. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M092072

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

von Gunten, Stephan (2020). The Future of Pharmacology: Towards More Personalized Pharmacotherapy and Reverse Translational Research. Pharmacology, 105(1-2), pp. 1-2. Karger 10.1159/000505216

Spirk, David; Noll, Sarah; Burnier, Michel; Rimoldi, Stefano; Noll, Georg; Sudano, Isabella (2020). First Line CombinAtion Therapy in the Treatment of Stage II and III Hypertension (FLASH). Frontiers in cardiovascular medicine, 7(46), p. 46. Frontiers 10.3389/fcvm.2020.00046

Konstantinidou, Georgia; Rimessi, Alessandro (2020). Editorial: Oncogenic RAS-Dependent Reprogramming of Cellular Plasticity. Frontiers in oncology, 10(588), p. 588. Frontiers Research Foundation 10.3389/fonc.2020.00588

von Gunten, Stephan (2020). Secondary-Type Carbohydrate Modification as a Driver of Epithelial-Mesenchymal Transition and Features of Cancer Stem Cells. Pharmacology, 105(5-6), pp. 244-245. Karger 10.1159/000507003

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

Liakoni, Evangelia; Berger, Flavia; Klukowska-Rötzler, Jolanta; Kupferschmidt, Hugo; Haschke, Manuel; Exadaktylos, Aristomenis (2019). Characteristics of emergency department presentations requiring consultation of the national Poisons Information Centre. Swiss medical weekly, 149, w20164. EMH Media 10.4414/smw.2019.20164

Sebastian, Tim; Spirk, David; Engelberger, Rolf P; Dopheide, Jörn F.; Baumann, Frederic A; Barco, Stefano; Spescha, Rebecca; Leeger, Claudia; Kucher, Nils (2019). Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome. Thrombosis and haemostasis, 119(12), pp. 2064-2073. Thieme 10.1055/s-0039-1697955

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Spirk, David; Sebastian, Tim; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Mollet, Annette; Szucs, Thomas D; Kucher, Nils (2019). Venous Thromboembolism and Renal Impairment: Insights from the SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 45(8), pp. 851-858. Thieme Medical Publishers 10.1055/s-0039-1698770

Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Crowley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2019). TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell death & disease, 10(10), p. 700. Nature Publishing Group 10.1038/s41419-019-1938-x

Brandl, Fabian; Merten, Hannes; Zimmermann, Martina; Béhé, Martin; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins. Journal of controlled release, 307, pp. 379-392. Elsevier 10.1016/j.jconrel.2019.06.030

Lorenzer, Cornelia; Streußnig, Sonja; Tot, Emilia; Winkler, Anna-Maria; Merten, Hannes; Brandl, Fabian; Sayers, Edward J; Watson, Peter; Jones, Arwyn T; Zangemeister-Wittke, Uwe; Plückthun, Andreas; Winkler, Johannes (2019). Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing. European journal of pharmaceutics and biopharmaceutics, 141, pp. 37-50. Elsevier 10.1016/j.ejpb.2019.05.015

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116

Rossi Sebastiano, Matteo; Konstantinidou, Georgia (2019). Targeting Long Chain Acyl-CoA Synthetases for Cancer Therapy. International journal of molecular sciences, 20(15) Molecular Diversity Preservation International MDPI 10.3390/ijms20153624

Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1

Karra, Laila; Gangwar, Roopesh Singh; Puzzovio, Pier Giorgio; Fyhrquist, Nanna; Minai-Fleminger, Yael; Landolina, Nadine; Simon, Hans-Uwe; Alenius, Harri; Leibovici, Vera; Simon, Dagmar; Levi-Schaffer, Francesca (2019). CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response. Allergy, 74(7), pp. 1377-1380. Wiley 10.1111/all.13724

Bruno, Andreina; Di Sano, Caterina; Lorusso, Francesco; Dino, Paola; Russo, Domenica; Ballacchino, Antonella; Gallina, Salvatore; Modica, Domenico Michele; Chiappara, Giuseppina; Simon, Hans-Uwe; Pace, Elisabetta (2019). Notch-1 decreased expression contributes to leptin receptor downregulation in nasal epithelium from allergic turbinates. Biochimica et biophysica acta - molecular basis of disease, 1865(6), pp. 1642-1650. Elsevier 10.1016/j.bbadis.2019.03.016

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Simon, Dagmar; Simon, Hans-Uwe (2019). Therapeutic strategies for eosinophilic dermatoses. Current opinion in pharmacology, 46, pp. 29-33. Elsevier 10.1016/j.coph.2019.01.002

Leviatan Ben-Arye, Shani; Schneider, Christoph; Yu, Hai; Bashir, Salam; Chen, Xi; von Gunten, Stephan; Padler-Karavani, Vered (2019). Differential Recognition of Diet-Derived Neu5Gc-Neoantigens on Glycan Microarrays by Carbohydrate-Specific Pooled Human IgG and IgA Antibodies. Bioconjugate chemistry, 30(5), pp. 1565-1574. American Chemical Society 10.1021/acs.bioconjchem.9b00273

Sokollik, Christiane; Simon, Hans-Uwe (2019). [Eosinophilic granulocytes-Physiology and pathophysiology]. Zeitschrift für Rheumatologie, 78(4), pp. 306-312. Springer-Medizin-Verlag 10.1007/s00393-018-0574-7

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2019). Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms. Biochimica et biophysica acta - molecular basis of disease, 1865(4), pp. 774-781. Elsevier 10.1016/j.bbadis.2018.12.022

Yadav, Sandeep Kumar; Stojkov, Darko; Feigelson, Sara W; Roncato, Francesco; Simon, Hans-Uwe; Yousefi, Shida; Alon, Ronen (2019). Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration. Journal of leukocyte biology, 105(4), pp. 755-766. Society for Leukocyte Biology 10.1002/JLB.3A1118-437RR

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Simon, Dagmar; Wollenberg, Andreas; Renz, Harald; Simon, Hans-Uwe (2019). Atopic Dermatitis: Collegium Internationale Allergologicum (CIA) Update 2019. International archives of allergy and immunology, 178(3), pp. 207-218. Karger 10.1159/000497383

Mortezavi, Ashkan; Salemi, Souzan; Kranzbühler, Benedikt; Gross, Oliver; Sulser, Tullio; Simon, Hans-Uwe; Eberli, Daniel (2019). Inhibition of autophagy significantly increases the antitumor effect of Abiraterone in prostate cancer. World journal of urology, 37(2), pp. 351-358. Springer-Verlag 10.1007/s00345-018-2385-5

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Schnetzler, Gabriel; Bremgartner, Markus F; Grossmann Straessle, Regina; Spirk, David; Tay, Fabian; Troxler Saxer, Rahel; Traber, Martin (2019). Evolution to a Competency-Based Training Curriculum for Pharmaceutical Medicine Physicians in Switzerland. Frontiers in Pharmacology, 10(164), p. 164. Frontiers 10.3389/fphar.2019.00164

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 1-8. Hogrefe 10.1024/1661-8157/a003250

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 469-476. Hogrefe 10.1024/1661-8157/a003222

Merten, Hannes; Schaefer, Jonas V; Brandl, Fabian; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Facile Site-Specific Multiconjugation Strategies in Recombinant Proteins Produced in Bacteria. Methods in molecular biology, 2033, pp. 253-273. Springer 10.1007/978-1-4939-9654-4_17

Verschoor, Daniëlle; von Gunten, Stephan (2019). Allergy and Atopic Diseases: An Update on Experimental Evidence. International archives of allergy and immunology, 180(4), pp. 235-243. Karger 10.1159/000504439

Simon, Dagmar; Simon, Hans-Uwe (2019). The role of pharmacists (In Press). In: Brockow, Brockow; Mortz, Charlotte (eds.) Global atlas of skin allergy (pp. 276-278). European academy of allergy and clinical immunology

Keller, Sarah A; Klukowska-Rötzler, Jolanta; Schenk-Jaeger, Katharina M; Kupferschmidt, Hugo; Exadaktylos, Aristomenis; Lehmann, Beat; Liakoni, Evangelia (2018). Mushroom Poisoning-A 17 Year Retrospective Study at a Level I University Emergency Department in Switzerland. International journal of environmental research and public health, 15(12) Molecular Diversity Preservation International MDPI 10.3390/ijerph15122855

Sebastian, Tim; Hakki, Lawrence O; Spirk, David; Baumann, Frederic A; Périard, Daniel; Banyai, Martin; Spescha, Rebecca S; Kucher, Nils; Engelberger, Rolf P (2018). Rivaroxaban or vitamin-K antagonists following early endovascular thrombus removal and stent placement for acute iliofemoral deep vein thrombosis. Thrombosis research, 172, pp. 86-93. Elsevier 10.1016/j.thromres.2018.10.027

Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488

Stanczak, Michal A; Siddiqui, Shoib S; Trefny, Marcel P; Thommen, Daniela S; Frias Boligan, Kayluz; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael S; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghan; Amos, Christopher I; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E; Varki, Ajit; ... (2018). Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells. Journal of clinical investigation, 128(11), pp. 4912-4923. American Society for Clinical Investigation 10.1172/JCI120612

Eberli, Daniel; Horst, Maya; Mortezavi, Ashkan; Andersson, Karl-Erik; Gobet, Rita; Sulser, Tullio; Simon, Hans-Uwe; Salemi, Souzan (2018). Increased autophagy contributes to impaired smooth muscle function in neurogenic lower urinary tract dysfunction. Neurourology and urodynamics, 37(8), pp. 2414-2424. Wiley-Liss 10.1002/nau.23705

Rohner, Lionel; Reinhart, Ramona; Hagmann, Björn; Odermatt, Andrea; Babirye, Annet; Kaufmann, Thomas; Fux, Michaela (2018). FcɛRI cross-linking and IL-3 protect human basophils from intrinsic apoptotic stress. The Journal of allergy and clinical immunology, 142(5), 1647-1650.e3. Elsevier 10.1016/j.jaci.2018.06.040

Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992

Miserez, A R; Martin, F J; Spirk, David (2018). DIAgnosis and Management Of familial hypercholesterolemia in a Nationwide Design (DIAMOND-FH): Prevalence in Switzerland, clinical characteristics and the diagnostic value of clinical scores. Atherosclerosis, 277, pp. 282-288. Elsevier 10.1016/j.atherosclerosis.2018.08.009

Adams, Olivia Joan; Stanczak, Michal A; von Gunten, Stephan; Läubli, Heinz (2018). Targeting sialic acid-Siglec interactions to reverse immune suppression in cancer. Glycobiology, 28(9), pp. 640-647. Oxford University Press 10.1093/glycob/cwx108

Miethe, Sarah; Guarino, Maria; Alhamdan, Fahd; Simon, Hans-Uwe; Renz, Harald; Dufour, Jean-François; Potaczek, Daniel P; Garn, Holger (2018). Effects of obesity on asthma: immunometabolic links. Polish archives of internal medicine, 128(7-8), pp. 469-477. Medycyna Praktyczna, Kraków, Poland 10.20452/pamw.4304

Arnold, Isabelle C; Artola-Borán, Mariela; Tallón de Lara, Paulino; Kyburz, Andreas; Taube, Christian; Ottemann, Karen; van den Broek, Maries; Yousefi, Shida; Simon, Hans-Uwe; Müller, Anne (2018). Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. Journal of experimental medicine, 215(8), pp. 2055-2072. Rockefeller University Press 10.1084/jem.20172049

Huwiler, Andrea; Pfeilschifter, Josef (2018). Sphingolipid signaling in renal fibrosis. Matrix biology, 68-69, pp. 230-247. Elsevier 10.1016/j.matbio.2018.01.006

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Sauser, Julien; Nutten, Sophie; de Groot, Nanda; Pecquet, Sophie; Simon, Dagmar; Simon, Hans-Uwe; Spergel, Jonathan M; Koletzko, Sibylle; Blanchard, Carine (2018). Partially Hydrolyzed Whey Infant Formula: Literature Review on Effects on Growth and the Risk of Developing Atopic Dermatitis in Infants from the General Population. International archives of allergy and immunology, 177(2), pp. 123-134. Karger 10.1159/000489861

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J; Arron, Joseph R; Bochner, Bruce S; Collins, Margaret H; Kahn, Jean-Emmanuel; Fulkerson, Patricia C; Gleich, Gerald J; Gopal-Srivastava, Rashmi; Jacobsen, Elizabeth A; Leiferman, Kristen M; Francesca, Levi-Schaffer; Mathur, Sameer K; Minnicozzi, Michael; Prussin, Calman; Rothenberg, Marc E; Roufosse, Florence; Sable, Kathleen; Simon, Dagmar; ... (2018). Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of leukocyte biology, 104(1), pp. 69-83. Society for Leukocyte Biology 10.1002/JLB.5MR0118-028R

Reinhart, Ramona; Kaufmann, Thomas (2018). IL-4 enhances survival of in vitro-differentiated mouse basophils through transcription-independent signaling downstream of PI3K. Cell death & disease, 9(7), p. 713. Nature Publishing Group 10.1038/s41419-018-0754-z

Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

Huwiler, Andrea; Zangemeister-Wittke, Uwe (2018). The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: recent findings and new perspectives. Pharmacology & therapeutics, 185, pp. 34-49. Elsevier 10.1016/j.pharmthera.2017.11.001

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Sebastian, Tim; Dopheide, Jörn F.; Engelberger, Rolf P.; Spirk, David; Kucher, Nils (2018). Outcomes of endovascular reconstruction of the inferior vena cava with self-expanding nitinol stents. Journal of vascular surgery. Venous and lymphatic disorder, 6(3), pp. 312-320. Elsevier 10.1016/j.jvsv.2017.11.012

Späth, Peter Julius (2018). Essentials of the Production of Safe and Efficacious State-of-the-Art Polyclonal IgG Concentrates. In: Imbach, P. (ed.) Antibody Therapy (pp. 151-173). Springer 10.1007/978-3-319-68038-5_12

Wahn, Volker; Späth, Peter Julius (2018). Historical Aspects of Polyclonal IgG Preparations. In: Imbach, P. (ed.) Antibody Therapy (pp. 121-132). Springer 10.1007/978-3-319-68038-5_10

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Gevaert, Elien; Yousefi, Shida; Bachert, Claus; Simon, Hans-Uwe (2018). Reply. The Journal of allergy and clinical immunology, 141(3), pp. 1164-1165. Elsevier 10.1016/j.jaci.2017.05.048

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493

Simon, Hans-Uwe; Bieber, Thomas (2018). Allergy - Committed to Progress in Allergy and Immunology. Allergy, 73(3), p. 527. Wiley-Blackwell 10.1111/all.13412

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V; Arama, Eli; Baehrecke, Eric H; Barlev, Nickolai A; Bazan, Nicolas G; Bernassola, Francesca; Bertrand, Mathieu J M; Bianchi, Katiuscia; Blagosklonny, Mikhail V; ... (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell death and differentiation, 25(3), pp. 486-541. Nature Publishing Group 10.1038/s41418-017-0012-4

Haas, Quentin; Simillion, Cedric André Marie; von Gunten, Stephan (2018). A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future? Frontiers in oncology, 8, p. 68. Frontiers Research Foundation 10.3389/fonc.2018.00068

Späth, Peter Julius (2018). Current IgG Products and Future Perspectives. In: Imbach, P. (ed.) Antibody Therapy (pp. 175-202). Springer 10.1007/978-3-319-68038-5_13

Wicki, Simone; Gurzeler, Ursina; Corazza, Nadia; Genitsch, Vera; Wong, Wendy Wei-Lynn; Kaufmann, Thomas (2018). Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss. International journal of molecular sciences, 19(3) Molecular Diversity Preservation International MDPI 10.3390/ijms19030684

Eresch, Jeanette; Stumpf, Martin; Koch, Alexander; Vutukuri, Rajkumar; Ferreirós, Nerea; Schreiber, Yannick; Schröder, Katrin; Devraj, Kavi; Popp, Rüdiger; Huwiler, Andrea; Hattenbach, Lars-Olof; Pfeilschifter, Josef; Pfeilschifter, Waltraud (2018). Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. Investigative ophthalmology & visual science, 59(2), pp. 653-661. Association for Research in Vision and Ophthalmology 10.1167/iovs.17-22544

Wang, Xiaoliang; Yousefi, Shida; Simon, Hans-Uwe (2018). Necroptosis and neutrophil-associated disorders. Cell death & disease, 9(2), p. 111. Nature Publishing Group 10.1038/s41419-017-0058-8

Vasilakaki, Sofia; Pastukhov, Oleksandr; Mavromoustakos, Thomas; Huwiler, Andrea; Kokotos, George (2018). Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells. Molecules, 23(1) Molecular Diversity Preservation International MDPI 10.3390/molecules23010158

Simon, Hans-Uwe (2018). International Archives of Allergy and Immunology: A Commitment to Serving the Community Worldwide. International archives of allergy and immunology, 175(1-2), pp. 3-4. Karger 10.1159/000485942

Simon, Dagmar; Page, Basile; Vogel, Monique; Bussmann, Christian; Blanchard, Carine; Straumann, Alex; Simon, Hans-Uwe (2018). Evidence of an abnormal epithelial barrier in active, untreated and corticosteroid-treated eosinophilic esophagitis. Allergy, 73(1), pp. 239-247. Wiley-Blackwell 10.1111/all.13244

Reinhart, Ramona; Rohner, Lionel; Wicki, Simone; Fux, Michaela; Kaufmann, Thomas (2018). BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells. Cell death and differentiation, 25(1), pp. 204-216. Nature Publishing Group 10.1038/cdd.2017.154

Blondon, Marc; Spirk, David; Kucher, Nils; Aujesky, Drahomir; Hayoz, Daniel; Beer, Jürg H; Husmann, Marc; Frauchiger, Beat; Korte, Wolfgang; Wuillemin, Walter Alfred; Bounameaux, Henri; Righini, Marc; Nendaz, Mathieu (2018). Comparative Performance of Clinical Risk Assessment Models for Hospital-Acquired Venous Thromboembolism in Medical Patients. Thrombosis and haemostasis, 118(1), pp. 82-89. Schattauer 10.1160/TH17-06-0403

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.

Beyer, Sandra; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2018). Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. Cellular physiology and biochemistry, 47(6), pp. 2522-2533. Karger 10.1159/000491625

Liu, He; He, Zhaoyue; Bode, Peter; Moch, Holger; Simon, Hans-Uwe (2018). Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Frontiers in oncology, 8(366), p. 366. Frontiers Research Foundation 10.3389/fonc.2018.00366

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Adams, Olivia Joan; von Gunten, Stephan (2018). Recent Advances in Experimental Allergy. International archives of allergy and immunology, 177(4), pp. 281-289. Karger 10.1159/000494440

Hübner, Simona T; Bertoli, Raffaela; Rätz Bravo, Alexandra E; Schaueblin, Martina; Haschke, M.; Scherer, Kathrin; Ceschi, Alessandro; Leuppi-Taegtmeyer, Anne B (2018). C-Reactive Protein and Procalcitonin in Case Reports of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. International archives of allergy and immunology, 176(1), pp. 44-54. Karger 10.1159/000487670

Liakoni, Evangelia; Gartwyl, Fabienne; Ricklin, Meret; Exadaktylos, Aristomenis; Krähenbühl, Stephan (2018). Psychoactive substances and violent offences: A retrospective analysis of presentations to an urban emergency department in Switzerland. PLoS ONE, 13(3), e0195234. Public Library of Science 10.1371/journal.pone.0195234

Spirk, David; Noll, Sarah; Burnier, Michel; Rimoldi, Stefano; Noll, Georg; Sudano, Isabella (2018). Effect of Home Blood Pressure Monitoring on Patient's Awareness and Goal Attainment Under Antihypertensive Therapy: The Factors Influencing Results in Anti-HypertenSive Treatment (FIRST) Study. Kidney & blood pressure research, 43(3), pp. 979-986. Karger 10.1159/000490687

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416

Wahn, Ulrich; Matricardi, Paolo M; Bieber, Thomas; Bousquet, Jean; Grattan, Clive; Simon, Hans-Uwe; Muraro, Antonella; Agache, Ioana (2017). Food allergy in EAACI journals (2016). Pediatric allergy and immunology, 28(8), pp. 825-830. Wiley-Blackwell 10.1111/pai.12830

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086

Schwalm, Stephanie; Beyer, Sandra; Frey, Helena; Haceni, Riad; Grammatikos, Georgios; Thomas, Dominique; Geisslinger, Gerd; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2017). Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction. American journal of pathology, 187(11), pp. 2413-2429. Elsevier 10.1016/j.ajpath.2017.06.017

Spirk, David; Stuck, Anna K.; Hager, A; Engelberger, Rolf P.; Aujesky, Drahomir; Kucher, Nils (2017). Electronic alert system for improving appropriate thromboprophylaxis in hospitalized medical patients: a randomized controlled trial. Journal of thrombosis and haemostasis, 15(11), pp. 2138-2146. Wiley-Blackwell 10.1111/jth.13812

Galluzzi, Lorenzo; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cecconi, Francesco; Choi, Augustine M; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Debnath, Jayanta; Deretic, Vojo; Dikic, Ivan; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Fulda, Simone; Gewirtz, David A; Green, Douglas R; Hansen, Malene; ... (2017). Molecular definitions of autophagy and related processes. The EMBO Journal, 36(13), pp. 1811-1836. EMBO Press 10.15252/embj.201796697

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Muraro, Antonella; Lemanske, Robert F; Castells, Mariana; Torres, Maria J; Khan, David; Simon, Hans-Uwe; Bindslev-Jensen, Carsten; Burks, Wesley; Poulsen, Lars K; Sampson, Hugh A; Worm, Margitta; Nadeau, Kari C (2017). Precision Medicine in Allergic Disease - Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Allergy, 72(7), pp. 1006-1021. Wiley-Blackwell 10.1111/all.13132

Engelberger, Rolf P.; Stuck, Anna; Spirk, David; Willenberg, Torsten; Haine, Axel; Périard, Daniel; Baumgartner, Iris; Kucher, Nils (2017). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute ilio-femoral deep vein thrombosis: one-year follow-up data of a randomized-controlled trial. Journal of thrombosis and haemostasis, 15(7), pp. 1351-1360. Wiley-Blackwell 10.1111/jth.13709

Vicari, Alain P; Schoepfer, Alain M; Meresse, Bertrand; Goffin, Laurence; Léger, Olivier; Josserand, Soheila; Guégan, Nicolas; Yousefi, Shida; Straumann, Alex; Cerf-Bensussan, Nadine; Simon, Hans-Uwe; Chvatchko, Yolande (2017). Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. mAbs, 9(6), pp. 927-944. Taylor & Francis 10.1080/19420862.2017.1332553

Späth, Peter Julius; Schneider, Christoph; von Gunten, Stephan (2017). Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations. Archivum immunologiae et therapiae experimentalis, 65(3), pp. 215-231. Springer 10.1007/s00005-016-0422-x

Gevaert, Elien; Zhang, Nan; Krysko, Olga; Lan, Feng; Holtappels, Gabriële; De Ruyck, Natalie; Nauwynck, Hans; Yousefi, Shida; Simon, Hans-Uwe; Bachert, Claus (2017). Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in severe airway inflammation. The Journal of allergy and clinical immunology, 139(6), 1849-1860.e6. Elsevier 10.1016/j.jaci.2017.01.019

Frias Boligan, Kayluz; von Gunten, Stephan (2017). Innate lymphoid cells in asthma: cannabinoids on the balance. Allergy, 72(6), pp. 839-841. Wiley-Blackwell 10.1111/all.13145

Pilch, Kjara S; Späth, Peter Julius; Yuki, Nobuhiro; Wakerley, Benjamin R (2017). Therapeutic complement inhibition: a promising approach for treatment of neuroimmunological diseases. Expert review of neurotherapeutics, 17(6), pp. 579-591. Expert Reviews 10.1080/14737175.2017.1282821

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

Petrova-Slater, Iveta; Denegri, Andrea; Pasotti, Elena; Rossi, Maria Grazia; Spirk, David; Riesen, Walter F; Moccetti, Tiziano; Moccetti, Marco (2017). [Inhibitors of PCSK9]. Revue médicale suisse, 13(558), pp. 821-825. Médecine & Hygiène

Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40

Hsieh, Louise Tzung-Harn; Nastase, Madalina-Viviana; Roedig, Heiko; Zeng-Brouwers, Jinyang; Poluzzi, Chiara; Schwalm, Stephanie; Fork, Christian; Tredup, Claudia; Brandes, Ralf P; Wygrecka, Malgorzata; Huwiler, Andrea; Pfeilschifter, Josef; Schaefer, Liliana (2017). Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants. International journal of molecular sciences, 18(3) Molecular Diversity Preservation International MDPI 10.3390/ijms18030595

Mortezavi, Ashkan; Salemi, Souzan; Rupp, Niels J; Rüschoff, Jan Hendrik; Hermanns, Thomas; Poyet, Cedric; Randazzo, Marco; Simon, Hans-Uwe; Moch, Holger; Sulser, Tullio; Wild, Peter; Eberli, Daniel (2017). Negative LC3b immunoreactivity in cancer cells is an independent prognostic predictor of prostate cancer specific death. OncoTarget, 8(19), pp. 31765-31774. Impact Journals LLC 10.18632/oncotarget.15986

Sharma, Sachin; Kaufmann, Thomas; Biswas, Subhrajit (2017). Impact of inhibitor of apoptosis proteins on immune modulation and inflammation. Immunology and cell biology, 95(3), pp. 236-243. Nature Publishing Group 10.1038/icb.2016.101

McCracken, A N; McMonigle, R J; Tessier, J; Fransson, R; Perryman, M S; Chen, B; Keebaugh, A; Selwan, E; Barr, S A; Kim, S M; Roy, S G; Liu, G; Fallegger, D; Sernissi, L; Brandt, C; Moitessier, N; Snider, A J; Clare, S; Müschen, M; Huwiler, Andrea; ... (2017). Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation. Leukemia, 31(3), pp. 669-677. Nature Publishing Group 10.1038/leu.2016.244

Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008

Simon, Hans-Uwe; Friis, Robert; Tait, Stephen W G; Ryan, Kevin M (2017). Retrograde signaling from autophagy modulates stress responses. Science signaling, 10(468) American Association for the Advancement of Science 10.1126/scisignal.aag2791

Stuck, Anna K.; Spirk, David; Schaudt, Jil; Kucher, Nils (2017). Risk assessment models for venous thromboembolism in acutely ill medical patients. A systematic review. Thrombosis and haemostasis, 117(4), pp. 801-808. Schattauer 10.1160/TH16-08-0631

Benarafa, Charaf; Simon, Hans-Uwe (2017). Role of granule proteases in the life and death of neutrophils. Biochemical and biophysical research communications, 482(3), pp. 473-481. Academic Press 10.1016/j.bbrc.2016.11.086

Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, Michaela (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850

Lejeune, Alice; Martin, Luise; Santibanez, Sabine; Thee, Stephanie; Gratopp, Alexander; Späth, Peter Julius; Mankertz, Annette; Kallinich, Tilmann; von Bernuth, Horst (2017). Postexposure prophylaxis with intravenous immunoglobulin G prevents infants from getting measles. Acta paediatrica, 106(1), pp. 174-177. Wiley 10.1111/apa.13634

Blanchard, C.; Simon, Dagmar; Schoepfer, A.; Straumann, A.; Simon, Hans-Uwe (2017). Eosinophilic esophagitis: unclear roles of IgE and eosinophils. Journal of internal medicine, 281(5), pp. 448-457. Blackwell Scientific Publications 10.1111/joim.12568

Simon, Hans-Uwe; Friis, Robert; Colombo, María I. (2017). Autophagy. In: eLS Citable reviews in the life sciences (pp. 1-10). Wiley 10.1002/9780470015902.a0021581.pub2

Ioris, Rafael M.; Galié, Mirco; Ramadori, Giorgio; Anderson, Jason G.; Charollais, Anne; Konstantinidou, Georgia; Brenachot, Xavier; Aras, Ebru; Goga, Algera; Ceglia, Nicholas; Sebastián, Carlos; Martinvalet, Denis; Mostoslavsky, Raul; Baldi, Pierre; Coppari, Roberto (2017). SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity. Cell reports, 18(8), pp. 1858-1868. Cell Press 10.1016/j.celrep.2017.01.065

Kouskoura, Thaleia; Katsaros, Christos; von Gunten, Stephan (2017). The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM). Frontiers in physiology, 8(67), p. 67. Frontiers Research Foundation 10.3389/fphys.2017.00067

Graumann, Rebecca; Di Capua, Gabriella A; Oyarzún, Juan E; Vásquez, Marcos A; Liao, Christine; Brañes, Jorge A; Roa, Iván; Casanello, Paola; Corvalán, Alejandro H; Owen, Gareth I; Delgado, Iris; Zangemeister-Wittke, Uwe; Ziegler, Annemarie (2017). Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer. PLoS ONE, 12(5), e0177244. Public Library of Science 10.1371/journal.pone.0177244

Schneider, Christoph; Illi, Marlies; Lötscher, Marius; Wehrli, Marc; von Gunten, Stephan (2017). Isolation of Antibodies from Human Plasma, Saliva, Breast Milk, and Gastrointestinal Fluid. Methods in molecular biology, 1643, pp. 23-31. Springer 10.1007/978-1-4939-7180-0_3

Bousquet, Jean; Grattan, Clive; Bieber, Thomas; Matricardi, Paolo; Simon, Hans-Uwe; Wahn, Ulrich; Muraro, Antonella; Hellings, Peter W; Agache, Ioana (2017). Prediction and prevention of allergy and asthma in EAACI journals (2016). Clinical and translational allergy, 7(46), p. 46. BioMed Central 10.1186/s13601-017-0185-4

Simon, Dagmar; Straumann, Alex; Schoepfer, Alain M; Simon, Hans-Uwe (2017). Current concepts in eosinophilic esophagitis. Allergo journal international, 26(7), pp. 258-266. Springer 10.1007/s40629-017-0037-8

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Bussmann, Christian; Schoepfer, Alain M; Safroneeva, Ekaterina; Haas, Nadine; Godat, Sébastien; Sempoux, Christine; Simon, Hans-Uwe; Straumann, Alex (2016). Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy, 48(12), pp. 1069-1075. Thieme 10.1055/s-0042-117274

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Leu, T; Rauthe, S; Wirth, C; Simon, H-U; Kunzmann, V; Hebestreit, H; Kunzmann, S; Simon, Hans-Uwe (2016). [The Lymphoid Variant of HES (L-HES) as Differential Diagnose of Severe Asthma in Childhood]. Klinische Pädiatrie, 228(06/07), pp. 319-324. Thieme 10.1055/s-0042-112593

Sudo, Makoto; Miyaji, Kazuki; Späth, Peter Julius; Morita-Matsumoto, Kana; Yamaguchi, Yoshiki; Yuki, Nobuhiro (2016). Polyclonal IgM and IgA block in vitro complement deposition mediated by anti-ganglioside antibodies in autoimmune neuropathies. International immunopharmacology, 40, pp. 11-15. Elsevier 10.1016/j.intimp.2016.08.019

Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311

Tuzlak, Selma; Kaufmann, Thomas; Villunger, Andreas (2016). Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis. Genes & development, 30(19), pp. 2133-2151. Cold Spring Harbor Laboratory Press 10.1101/gad.289298.116

Fernandez Marrero, Yuniel; Spinner, S; Jost, P J; Kaufmann, Thomas (2016). Survival control of malignant lymphocytes by anti-apoptotic MCL-1. Leukemia, 30(11), pp. 2152-2159. Nature Publishing Group 10.1038/leu.2016.213

Spirk, David; Aujesky, Drahomir; Stuck, Anna K; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Kucher, Nils (2016). Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 42(6), pp. 642-649. Thieme Medical Publishers 10.1055/s-0036-1584131

Padanad, Mahesh S; Konstantinidou, Georgia; Venkateswaran, Niranjan; Melegari, Margherita; Rindhe, Smita; Mitsche, Matthew; Yang, Chendong; Batten, Kimberly; Huffman, Kenneth E; Liu, Jingwen; Tang, Ximing; Rodriguez-Canales, Jaime; Kalhor, Neda; Shay, Jerry W; Minna, John D; McDonald, Jeffrey; Wistuba, Ignacio I; DeBerardinis, Ralph J; Scaglioni, Pier Paolo (2016). Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis. Cell reports, 16(6), pp. 1614-1628. Cell Press 10.1016/j.celrep.2016.07.009

Werfel, Thomas; Allam, Jean-Pierre; Biedermann, Tilo; Eyerich, Kilian; Gilles, Stefanie; Guttman-Yassky, Emma; Hoetzenecker, Wolfram; Knol, Edward; Simon, Hans-Uwe; Wollenberg, Andreas; Bieber, Thomas; Lauener, Roger; Schmid-Grendelmeier, Peter; Traidl-Hoffmann, Claudia; Akdis, Cezmi A (2016). Cellular and molecular immunologic mechanisms in patients with atopic dermatitis. Journal of allergy and clinical immunology, 138(2), pp. 336-349. Mosby 10.1016/j.jaci.2016.06.010

Silbernagel, Günther; Spirk, David; Hager, Adrian; Baumgartner, Iris; Kucher, Nils (2016). Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial. Journal of the American Heart Association, 5(7), pp. 1-7. American Heart Association 10.1161/JAHA.116.003776

Vasilakaki, Sofia; Barbayianni, Efrosini; Magrioti, Victoria; Pastukhov, Oleksandr; Constantinou-Kokotou, Violetta; Huwiler, Andrea; Kokotos, George (2016). Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells. Bioorganic & medicinal chemistry, 24(13), pp. 3029-3034. Elsevier 10.1016/j.bmc.2016.05.017

Bieber, T; Akdis, C; Lauener, R; Traidl-Hoffmann, C; Schmid-Grendelmeier, P; Schäppi, G; Allam, J-P; Apfelbacher, C; Augustin, M; Beck, L; Biedermann, T; Braun-Fahrländer, C; Chew, F T; Clavel, T; Crameri, R; Darsow, U; Deleuran, M; Dittlein, D; Duchna, H-W; Eichenfeld, L; ... (2016). Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine. Allergy, 71(5), pp. 588-592. Wiley-Blackwell 10.1111/all.12857

Muraro, Antonella; Lemanske, Robert F; Hellings, Peter W; Akdis, Cezmi A; Bieber, Thomas; Casale, Thomas B; Jutel, Marek; Ong, Peck Y; Poulsen, Lars K; Schmid-Grendelmeier, Peter; Simon, Hans-Uwe; Seys, Sven F; Agache, Ioana (2016). Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Journal of allergy and clinical immunology, 137(5), pp. 1347-1358. Mosby 10.1016/j.jaci.2016.03.010

D'Orsi, Beatrice; Engel, Tobias; Pfeiffer, Shona; Nandi, Saheli; Kaufmann, Thomas; Henshall, David C; Prehn, Jochen H M (2016). Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. Journal of neuroscience, 36(16), pp. 4564-4578. Society for Neuroscience 10.1523/JNEUROSCI.3780-15.2016

Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879

Dhayade, Sandeep; Kaesler, Susanne; Sinnberg, Tobias; Dobrowinski, Hyazinth; Peters, Stefanie; Naumann, Ulrike; Liu, He; Hunger, Robert E.; Thunemann, Martin; Biedermann, Tilo; Schittek, Birgit; Simon, Hans-Uwe; Feil, Susanne; Feil, Robert (2016). Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth. Cell reports, 14(11), pp. 2599-2610. Cell Press 10.1016/j.celrep.2016.02.028

Simon, Dagmar; Cianferoni, A; Spergel, J M; Aceves, S; Holbreich, M; Venter, C; Rothenberg, M E; Terreehorst, I; Muraro, A; Lucendo, A J; Schoepfer, A; Straumann, A; Simon, Hans-Uwe (2016). Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity. Allergy, 71(5), pp. 611-620. Wiley-Blackwell 10.1111/all.12846

Metcalfe, Dean D; Pawankar, Ruby; Ackerman, Steven J; Akin, Cem; Clayton, Frederic; Falcone, Franco H; Gleich, Gerald J; Irani, Anne-Marie; Johansson, Mats W; Klion, Amy D; Leiferman, Kristin M; Levi-Schaffer, Francesca; Nilsson, Gunnar; Okayama, Yoshimichi; Prussin, Calman; Schroeder, John T; Schwartz, Lawrence B; Simon, Hans-Uwe; Walls, Andrew F and Triggiani, Massimo (2016). Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases. World Allergy Organization journal, 9, p. 7. Wolters Kluwer Health Lippincott Williams & Wilkins 10.1186/s40413-016-0094-3

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Engert, A.; Balduini, C.; Brand, A.; Coiffier, B.; Cordonnier, C.; Dohner, H.; de Wit, T. D.; Eichinger, S.; Fibbe, W.; Green, T.; de Haas, F.; Iolascon, A.; Jaffredo, T.; Rodeghiero, F.; Salles, G.; Schuringa, J. J.; EHA, Roadmap for European Hematology Research (2016). The European Hematology Association Roadmap for European Hematology Research: a consensus document. Haematologica - the hematology journal, 101(2), pp. 115-208. Ferrata-Storti Foundation 10.3324/haematol.2015.136739

Chen, Bin; Roy, Saurabh G; McMonigle, Ryan J; Keebaugh, Andrew; McCracken, Alison N; Selwan, Elizabeth; Fransson, Rebecca; Fallegger, Daniel; Huwiler, Andrea; Kleinman, Michael T; Edinger, Aimee L; Hanessian, Stephen (2016). Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo. ACS Chemical Biology, 11(2), pp. 409-414. American Chemical Society 10.1021/acschembio.5b00761

Simon, Hans-Uwe; Simon, Dagmar (2016). Leserbrief zum Beitrag Hypereosinophilie. Swiss medical weekly, 16(4), p. 104. EMH Schweizerischer Ärzteverlag

Simon, Hans-Uwe; Radonjic, Susanne Irene (2016). Eosinophile Granulozyten. In: Biedermann, Tilo; Heppt, Werner; Renz, Harald; Röcken, Martin (eds.) Allergologie (pp. 77-85). Berlin, Heidelberg: Springer 10.1007/978-3-642-37203-2_7

Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356

Quast, Isaak; Keller, Christian W; Weber, Patrick; Schneider, Christoph; von Gunten, Stephan; Lünemann, Jan D (2016). Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation. Journal of neuroinflammation, 13, p. 42. BioMed Central 10.1186/s12974-016-0506-x

Simon, Hans-Uwe; Yousefi, Shida; Simon, Dagmar (2016). Basophils can form extracellular DNA traps independent of a functional NADPH oxidase. In: Maurer, Markus; Behrendt, Heidrum (eds.) Allergies: Current challenges and solutions. Proceedings of the 30th Symposium of the Collegium Internationale Allergologicum (CIA) (pp. 67-70). Ospedaletto (Pisa): Pacini editore Medicina

Carr, Tara F; Berdnikovs, Sergejs; Simon, Hans-Uwe; Bochner, Bruce S; Rosenwasser, Lanny J (2016). Eosinophilic bioactivities in severe asthma. World Allergy Organization journal, 9, p. 21. BioMed Central 10.1186/s40413-016-0112-5

Simon, Hans-Uwe; Zangemeister-Wittke, Uwe (2016). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer. Heidelberg: Springer

Coldewey, Sina M; Benetti, Elisa; Collino, Massimo; Pfeilschifter, Josef; Sponholz, Christoph; Bauer, Michael; Huwiler, Andrea; Thiemermann, Christoph (2016). Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis. Scientific Reports, 6, p. 27594. Nature Publishing Group 10.1038/srep27594

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Yousefi, Shida; Simon, Hans-Uwe (2016). NETosis - Does It Really Represent Nature's "Suicide Bomber"? Frontiers in immunology, 7(328), p. 328. Frontiers Research Foundation 10.3389/fimmu.2016.00328

Reinhart, Ramona; Wicki, Simone; Kaufmann, Thomas (2016). In Vitro Differentiation of Mouse Granulocytes. Methods in molecular biology, 1419, pp. 95-107. Humana Press 10.1007/978-1-4939-3581-9_8

Wuillemin, Walter; Spirk, David; Beer, Jürg; Baumgartner, Iris (2016). Schweizer Expertenkommentare zum Update der ACCP-Guidelines. Swiss Medical Forum, 16(49-50), pp. 1059-1060. EMH Swiss Medical Publishers

Djoumerska-Alexieva, Iglika; Roumenina, Lubka; Pashov, Anastas; Dimitrov, Jordan; Hadzhieva, Maya; Lindig, Sandro; Voynova, Elisaveta; Dimitrova, Petya; Ivanovska, Nina; Bockmeyer, Clemens; Stefanova, Zvetanka; Fitting, Catherine; Bläss, Markus; Claus, Ralf; von Gunten, Stephan; Kaveri, Srini; Cavaillon, Jean-Marc; Bauer, Michael; Vassilev, Tchavdar (2015). Intravenous Immunoglobulin with Enhanced Polyspecificity Improves Survival in Experimental Sepsis and Aseptic Systemic Inflammatory Response Syndromes. Molecular medicine, 21(1), p. 1. Feinstein Institute for Medical Research 10.2119/molmed.2014.00224

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Merten, Hannes; Brandl, Fabian; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2015). Antibody-Drug Conjugates for Tumor Targeting-Novel Conjugation Chemistries and the Promise of non-IgG Binding Proteins. Bioconjugate chemistry, 26(11), pp. 2176-2185. American Chemical Society 10.1021/acs.bioconjchem.5b00260

Leu, T; Simon, Hans-Uwe; Hebestreit, H; Kunzmann, S (2015). The Hypereosinophilic Syndromes in Childhood. Klinische Pädiatrie, 227(6-07), pp. 308-313. Thieme 10.1055/s-0035-1555792

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Tiligada, Ekaterini; Ishii, Masaru; Riccardi, Carlo; Spedding, Michael; Simon, Hans-Uwe; Teixeira, Mauro Martins; Cuervo, Mario Landys Chovel; Holgate, Stephen T; Levi-Schaffer, Francesca (2015). The expanding role of immunopharmacology: IUPHAR Review 16. British journal of pharmacology, 172(17), pp. 4217-4227. Wiley-Blackwell 10.1111/bph.13219

Urtz, Nicole; Gaertner, Florian; von Bruehl, Marie-Luise; Chandraratne, Sue; Rahimi, Faridun; Zhang, Lingli; Orban, Mathias; Barocke, Verena; Beil, Johannes; Schubert, Irene; Lorenz, Michael; Legate, Kyle R; Huwiler, Andrea; Pfeilschifter, Josef M; Beerli, Christian; Ledieu, David; Persohn, Elke; Billich, Andreas; Baumruker, Thomas; Mederos y Schnitzler, Michael; ... (2015). Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. Circulation research, 117(4), pp. 376-387. Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.115.306901

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Schröder, Matthias; Arlt, Olga; Schmidt, Helmut; Huwiler, Andrea; Angioni, Carlo; Pfeilschifter, Josef M; Schwiebs, Anja; Radeke, Heinfried H (2015). Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application. Biological chemistry, 396(6-7), pp. 795-802. De Gruyter 10.1515/hsz-2014-0287

Wünsche, Christin; Koch, Alexander; Goldschmeding, Roel; Schwalm, Stephanie; Meyer Zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2015). Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1851(5), pp. 519-526. Elsevier 10.1016/j.bbalip.2015.01.003

Koch, Alexander; Jäger, Manuel; Völzke, Anja; Grammatikos, Georgios; Zu Heringdorf, Dagmar Meyer; Huwiler, Andrea; Pfeilschifter, Josef (2015). Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration. Biological chemistry, 396(6-7), pp. 803-812. De Gruyter 10.1515/hsz-2014-0288

Spirk, David; Nendaz, M; Aujesky, Drahomir; Hayoz, D; Beer, J H; Husmann, M; Frauchiger, B; Korte, W; Wuillemin, Walter Alfred; Righini, M; Bounameaux, H; Kucher, Nils (2015). Predictors of thromboprophylaxis in hospitalised medical patients. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE). Thrombosis and haemostasis, 113(5), pp. 1127-1134. Schattauer 10.1160/TH14-06-0525

Engelberger, Rolf Peter; Spirk, David; Willenberg, Torsten Andreas; Alatri, Adriano; Do, Dai-Do; Baumgartner, Iris; Kucher, Nils (2015). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Circulation: Cardiovascular interventions, 8(1) Lippincott Williams & Wilkins 10.1161/CIRCINTERVENTIONS.114.002027

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137

Simon, Hans-Uwe (2015). Regulation of inflammation by cell death in allergic rhinitis. In: Akdis, Cezmi A.; Hellings, Peter W. (eds.) Global Atlas of Allergic Rhinitis and chronic rhinosinusitis (pp. 43-44). European Academy of Allergy and Clinical Immunology

Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15

Kaufmann, Thomas; Reinhart, Ramona; Wicki, Simone (2015). In vitro differentiation of mouse granulocytes. Programmed Cell Death: Methods and Protocols (In Press). In: Puthalakath, Hamsa; Hawkins, Christine (eds.) Programmed Cell Death: Methods and Protocols. Methods in Molecular Biology. Humana Press

Cortinas-Elizondo, F.; von Gunten, Stephan (2015). MicroRNA-155: microtuning the allergic concert. Allergy, 70(9), pp. 1035-1036. Wiley-Blackwell 10.1111/all.12673

Späth, Peter Julius; Granata, Guido; La Marra, Fabiola; Kuijpers, Taco W.; Quinti, Isabella (2015). On the Dark Side of Therapies with Immunoglobulin Concentrates: The Adverse Events. Frontiers in immunology, 6(11), p. 11. Frontiers Research Foundation 10.3389/fimmu.2015.00011

Riebenfeld, Daniela; Spirk, David; Mathis, Alexandra; Villiger, Lukas; Gerber, Philipp A; Gasser, Urs Erwin; Lehmann, Roger (2015). Treatment intensification with insulin glargine in patients with inadequately controlled type 2 diabetes improves glycaemic control with a high treatment satisfaction and no weight gain. Swiss medical weekly, 145, w14114. EMH Schweizerischer Ärzteverlag 10.4414/smw.2015.14114

Maier, Larissa J; Liakoni, Evangelia; Schildmann, Jan; Schaub, Michael P; Liechti, Matthias E (2015). Swiss University Students' Attitudes toward Pharmacological Cognitive Enhancement. PLoS ONE, 10(12), e0144402. Public Library of Science 10.1371/journal.pone.0144402

Liakoni, Evangelia; Schaub, Michael P; Maier, Larissa J; Glauser, Gaëlle-Vanessa; Liechti, Matthias E (2015). The Use of Prescription Drugs, Recreational Drugs, and "Soft Enhancers" for Cognitive Enhancement among Swiss Secondary School Students. PLoS ONE, 10(10), e0141289. Public Library of Science 10.1371/journal.pone.0141289

Ramadori, Giorgio; Konstantinidou, Georgia; Venkateswaran, Niranjan; Biscotti, Tommasina; Morlock, Lorraine; Galié, Mirco; Williams, Noelle S.; Luchetti, Michele; Santinelli, Alfredo; Scaglioni, Pier Paolo; Coppari, Roberto (2015). Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis. Cell metabolism, 21(1), pp. 117-125. Cell Press 10.1016/j.cmet.2014.11.020

Gaubitz, Christl; Oliveira, Taiana M.; Prouteau, Manoel; Leitner, Alexander; Karuppasamy, Manikandan; Konstantinidou, Georgia; Rispal, Delphine; Eltschinger, Sandra; Robinson, Graham C.; Thore, Stéphane; Aebersold, Ruedi; Schaffitzel, Christiane; Loewith, Robbie (2015). Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2. Molecular cell, 58(6), pp. 977-988. Cell Press 10.1016/j.molcel.2015.04.031

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/​jimmunol.1400028

Pastukhov, Oleksandr; Schalm, Stephanie; Zangemeister-Wittke, Uwe; Fabbro, Doriano; Bornancin, Frederic; Japtok, Lukasz; Kleuser, Burkhrad; Pfeilschifter, Josef; Huwiler, Andrea (2014). The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death. British journal of pharmacology, 171(24), pp. 5829-5844. Wiley-Blackwell 10.1111/bph.12886

von Gunten, Stephan (2014). Protein-glycan interactions as targets of intravenous/subcutaneous immunoglobulin (IVIg/SCIg) preparations. Clinical and experimental immunology, 178(S1), pp. 151-152. Blackwell Scientific Publications 10.1111/cei.12550

Frias Boligan, Kayluz; Mesa, Circe; Fernandez, Luis Enrique; von Gunten, Stephan (2014). Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense. Cellular and molecular life sciences, 72(7), pp. 1231-1248. Springer 10.1007/s00018-014-1799-5

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2014). Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy, 10(2), pp. 372-373. Landes Bioscience 10.4161/auto.27163

Stefan, Nikolas; Zimmermann, Martina; Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2014). Novel Prodrug-Like Fusion Toxin with Protease-Sensitive Bioorthogonal PEGylation for Tumor Targeting. Bioconjugate chemistry, 25(12), pp. 2144-2156. American Chemical Society 10.1021/bc500468s

Imeri, Faik; Fallegger, Daniel; Zivkovic, Aleksandra; Schwalm, Stephanie; Enzmann, Gaby; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Homann, Thomas; Kleuser, Burkhard; Pfeilschifter, Josef; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2014). Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology, 85, pp. 314-327. Elsevier 10.1016/j.neuropharm.2014.05.012

Sudo, Makoto; Yamaguchi, Yoshiki; Späth, Peter Julius; Matsumoto-Morita, Kana; Ong, Benjamin K.; Shahrizaila, Nortina; Yuki, Nobuhiro (2014). Different IVIG glycoforms affect in vitro inhibition of anti-ganglioside antibody-mediated complement deposition. PLoS ONE, 9(9), e107772. Public Library of Science 10.1371/journal.pone.0107772

Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010

Sewell, W. A. Carrock; Kerr, Jacqueline; Behr-Gross, Marie-Emmanuelle; Peter, Hans-Hartmut; Kreuth Ig Working Group, ; Späth, Peter Julius (2014). European consensus proposal for immunoglobulin therapies. European journal of immunology, 44(8), pp. 2207-2214. Wiley-VCH

Thangaiyan, Rabi; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells. Molecular carcinogenesis, 53(7), pp. 578-588. Wiley 10.1002/mc.22012

Späth, Peter Julius; Tamburin, Stefano; Borg, Christian; Caro, Xavier J.; Jann, Stefano; Clark, Alexander J.; Maginelli, Francesca; Sobue, Gen; Werhagen, Lars; Zanetta, Giampietro; Koike, Haruki; Vincent, Angela; Goebel, Andreas (2014). Immunoglobulin g for the treatment of chronic pain: report of an expert workshop. Pain medicine, 15(7), pp. 1072-1082. Wiley-Blackwell 10.1111/pme.12319

Andree, Maria; Seeger, Jens M.; Schüll, Stephan; Coutelle, Oliver; Wagner-Stippich, Diana; Wiegmann, Katja; Wunderlich, Claudia M.; Birkmann, Kerstin; Broxtermann, Pia; Witt, Axel; Fritsch, Melanie; Martinelli, Paola; Bielig, Harald; Lamkemeyer, Tobias; Rugarli, Elena I.; Kaufmann, Thomas; Sterner-Kock, Anja; Wunderlich, F. Thomas; Villunger, Andreas; Martins, L. Miguel; ... (2014). BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO journal, 33(19), pp. 2171-2187. Nature Publishing Group 10.15252/embj.201387244

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Imeri, Faik; Jashri, Ahmed; Bullazhi, Lulzime; Shabani, Agim; Mikhova, Bozhana; Dräger, Gerald; Popovski, Emil; Huwiler, Andrea (2014). Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death. Bioorganic & medicinal chemistry, 22(9), pp. 2655-2660. Elsevier 10.1016/j.bmc.2014.03.026

Stowell, Sean R.; Arthur, Connie M.; Mc Bride, Ryan; Berger, Oren; Razi, Nahid; Heimberg-Molinaro, Jamie; Rodrigues, Lilian C.; Gourdine, Jean-Philippe; Noll, Alexander J.; von Gunten, Stephan; Smith, David F.; Knirel, Yuriy A.; Paulson, James C.; Cummings, Richard D. (2014). Microbial glycan microarrays define key features of host-microbial interactions. Nature Chemical Biology, 10(6), pp. 470-476. Nature Publishing Group 10.1038/nchembio.1525

Simon, Dagmar; Straumann, A.; Simon, Hans-Uwe (2014). Eosinophilic esophagitis and allergy. Digestive diseases, 32(1-2), pp. 30-33. Karger 10.1159/000357006

von Gunten, Stephan (2014). Targeting Siglecs: Neue potenzielle Strategien zur Immuntherapie entzündlicher oder maligner Erkrankungen. Leading Opinions. Hämatologie & Onkologie(2), pp. 34-36. Universimed

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Simon, D.; Aeberhard, C.; Erdemoglu, Y.; Simon, H.-U. (2014). Th17 cells and tissue remodeling in atopic and contact dermatitis. Allergy, 69(1), pp. 125-131. Wiley-Blackwell 10.1111/all.12351

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Simon, Manuel; Stefan, Nikolas; Borsig, Lubor; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2014). Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation. Molecular cancer therapeutics, 2(13), pp. 375-385. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0523

Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2014). Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. Basic Clinical Pharmacology and Toxicology, 1(114), pp. 44-49. Wiley 10.1111/bcpt.12103

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Völzke, Anja; Koch, Alexander; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2014). Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1841(1), pp. 11-21. Elsevier 10.1016/j.bbalip.2013.09.009

Simon, Hans-Uwe; Friis, Robert (2014). ATG5: a distinct role in the nucleus. Autophagy, 10(1), pp. 176-177. Landes Bioscience 10.4161/auto.26916

Simon, Hans-Uwe; Straumann, Alex (2014). Immunopathogenesis of eosinophilic esophagitis. Digestive diseases, 32(1-2), pp. 11-14. Karger 10.1159/000357003

Houriet, C.; Simon, H.-U.; Simon, D. (2014). Hypereosinophilic Syndromes. Aktuelle Dermatologie, 40(4), pp. 127-132. Thieme 10.1055/s-0034-1365078

Radonjic-Hösli, Susanne; Simon, Hans-Uwe (2014). Eosinophils. Chemical immunology and allergy, 100, pp. 193-204. Karger 10.1159/000358735

Simon, Hans-Uwe (2014). Eosinophils. In: Global Atlas of Allergy (pp. 58-59). Zurich: EAACI

Yabal, Monica; Müller, Nicole; Adler, Heiko; Knies, Nathalie; Gross, Christina J.; Damgaard, Rune Busk; Kanegane, Hirokazu; Ringelhan, Marc; Kaufmann, Thomas; Heikenwächter, Mathias; Strasser, Andreas; Gross, Olaf; Ruland, Jürgen; Peschel, Christian; Gyrd-Hansen, Mads; Jost, Philipp J. (2014). XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation. Cell reports, 7(6), pp. 1795-1808. Cell Press 10.1016/j.celrep.2014.05.008

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Ring, J.; Akdis, C.; Lauener, R.; Schäppi, G.; Traidl-Hoffmann, C.; Akdis, M.; Ammann, W.; Behrendt, H.; Bieber, T.; Biedermann, T.; Bienenstock, J.; Blaser, K.; Braun-Fahrländer, C.; Brocknow, K.; Buters, J.; Crameri, R.; Darsow, U.; Denburg, J.A.; Eyerich, K.; Frei, R.; ... (2014). Global Allergy Forum and Second Davos Declaration 2013 Allergy: Barriers to cure - challenges and actions to be taken. Allergy, 69(8), pp. 978-982. Wiley-Blackwell 10.1111/all.12406

von Gunten, Stephan; Shoenfeld, Yehuda; Blank, Miri; Branch, Donald R.; Vassoöev, Tchavdar; Käsermann, Fabian; Bayy, Jagadeesh; Kaveri, Srini; Simon, Hans-Uwe (2014). IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist. Nature reviews - immunology, 14(5), pp. 349-350. Nature Publishing Group 10.1038/nri3401-c1

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2014). Eosinophil extracellular traps: potential role(s) in eosinophilic diseases. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from Mechanisms to Cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 87-89). Pisa: Pacini Editore S.p.A.

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2014). Eosinophil extracellular trap formation in response to thymic stromal lymphopoietin stimulation. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from mechanisms to cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 83-86). Pisa: Pacini Editore

Späth, Peter Julius (2014). A novel use of intravenous immunoglobulin is not restricted to complement hypercatabolism because of factor H deficiency. Progress in transplantation, 24(2), p. 120. InnoVision Communications 10.7182/pit2014750

Späth, Peter Julius (2014). Report from a rare diseases event in Targu Mures, Romania. Romanian Review of Laboratory Medicine, 22(3), pp. 397-398. Romanian Association of Medical Laboratories

Späth, Peter Julius (2014). A glance on recent progresses in diagnosis and treatment of primary immunodeficiencies. Romanian Review of Laboratory Medicine, 22(3), pp. 297-309. Romanian Association of Medical Laboratories 10.2478/rrlm-2014-0034

Kondo, Shunya; Bottos, Alessia; Allegood, Jeremy C.; Masson, Regis; Maurer, Francisca G.; Genoud, Christel; Kaeser, Patrick; Huwiler, Andrea; Murakami, Masato; Spiegel, Sarah; Hynes, Nancy E. (2014). Memo has a novel role in S1P signaling and crucial for vascular development. PLoS ONE, 9(4), e94114. Public Library of Science 10.1371/journal.pone.0094114

Pastukhov, Oleksandr; Schalm, Stephanie; Römer, Isolde; Pfeilschifter, Josef; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts. Cellular physiology and biochemistry, 34(1), pp. 119-133. Karger 10.1159/000362989

Simon, Hans-Uwe (2014). IL17, IL22 and tissue remodeling in atopic and contact dermatitis. In: Maurer, Marcus; Behrendt, Heidrun (eds.) Allergies: Current challenges and solutions (pp. 183-186). Paccini editore medicina

Schoepfer, Alain M.; Safroneeva, Ekaterina; Bussmann, Christian; Kuchen, Tanja; Portmann, Susanne; Simon, Hans-Uwe; Straumann, Alex (2013). Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation in a time-dependent manner. Gastroenterology, 145(6), 1230-1236.e2. Elsevier 10.1053/j.gastro.2013.08.015

Herold, Marco J.; Rohrbeck, Leona; Lang, Mathias J.; Grumont, Raelene; Gerondakis, Steve; Tai, Lin; Bouillet, Philippe; Kaufmann, Thomas; Strasser, Andreas (2013). Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein. EMBO REPORTS, 14(11), pp. 992-998. Nature 10.1038/embor.2013.152

Stoeckle, Christina; Rota, Ioanna A.; Tolosa, Eva; Haller, Christoph; Melms, Arthur; Adamopoulou, Eleni (2013). Isolation of myeloid dendritic cells and epithelial cells from human thymus. Journal of visualized experiments, 79(79), e50951. MYJoVE Corporation 10.3791/50951

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

Schulman, Jacqualyn J; Wright, Fiorrest A; Kaufmann, Thomas; Wojcikiewicz, Richard J H (2013). The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage. Journal of biological chemistry, 288(35), pp. 25340-25349. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.496570

He, Z.; Simon, H. U. (2013). Autophagy protects from liver injury. Cell death and differentiation, 20(7), pp. 850-851. Nature Publishing Group 10.1038/cdd.2013.43

Ke, Francine; Kaufmann, Thomas; Bouillet, Philippe; Strasser, Andreas; Kerr, Jeffrey; Voss, Anne K (2013). Consequences of the combined loss of BOK and BAK or BOK and BAX. Cell death & disease, 4(6), e650. Nature Publishing Group 10.1038/cddis.2013.176

Adamopoulou, Eleni; Tenzer, Stefan; Hillen, Nina; Klug, Paul; Rota, Ioanna A.; Tietz, Silvia; Gebhardt, Madlen; Stevanovic, Stefan; Schild, Hansjörg; Tolosa, Eva; Melms, Arthur; Stoeckle, Christina (2013). Exploring the MHC-peptide matrix of central tolerance in the human thymus. Nature communications, 4(2039), p. 2039. Nature Publishing Group 10.1038/ncomms3039

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2013). Extracellular DNA traps in allergic, infectzious, and autoimmune diseases. Allergy, 68(4), pp. 409-416. Wiley-Blackwell 10.1111/all.12111

Straumann, A.; Hoesli, S.; Bussmann, Ch.; Stuck, M.; Perkins, M.; Collins, L. P.; Payton, M.; Pettipher, R.; Hunter, M.; Steiner, J.; Simon, H.-U. (2013). Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis. Allergy, 68(3), pp. 375-385. Wiley-Blackwell 10.1111/all.12096

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

He, Zhaoyue; Simon, Hans-Uwe (2013). A novel link between p53 and ROS. Cell Cyle, 12(2), pp. 201-202. Landes Bioscience 10.4161/cc.23418

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Wojtalla, Anna; Fischer, Barbara; Kotelevets, Nataliya; Mauri, Francesco A; Sobek, Jens; Rehrauer, Hubert; Wotzkow, Carlos; Tschan, Mario P; Seckl, Michael J; Zangemeister-Wittke, Uwe; Arcaro, Alexandre (2013). Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clinical cancer research, 19(1), pp. 96-105. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-1138

von Gunten, Stephan; Wehrli, Marc; Simon, Hans-Uwe (2013). Cell death in immune thrombocytopenia: novel insights and perspectives. Seminars in hematology, 1(50), pp. 109-115. W.B. Saunders 10.1053/j.seminhematol.2013.03.016

Démoulins, Thomas; Bassi, Isabelle; Thomann-Harwood, Lisa; Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan; Mc Cullogh, Kenneth C (2013). Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells. Nanomedicine-Nanotechnology Biology and Medicine, 9(6), pp. 806-817. Elsevier 10.1016/j.nano.2013.01.002

von Gunten, Stephan; Schorer, Myriam Fabiola; Kollarik, M.; Beisswenger, C.; Lepper, P. M. (2013). Mechanisms and potential therapeutic targets in allergic inflammation: recent insights. Allergy, 68(12), pp. 1487-1498. Wiley-Blackwell 10.1111/all.12312

Bhabak, Krishna P.; Kleuser, Burkhard; Huwiler, Andrea; Arenz, Christoph (2013). Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues. Bioorganic & medicinal chemistry, 21(4), pp. 874-882. Elsevier 10.1016/j.bmc.2012.12.014

Koch, Alexander; Völzke, Anja; Puff, Bianca; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2013). PARγ agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca(2+)]i increases in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(11), pp. 1634-1643. Elsevier 10.1016/j.bbalip.2013.07.011

Albinet, V.; Bats, M-L; Huwiler, Andrea; Rochaix, P.; Chevreau, C.; Ségui, B.; Levande, T.; Andrieu-Abadie, N. (2013). Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells. Oncogene, 33(26), pp. 3364-3373. Nature Publishing Group 10.1038/onc.2013.303

Schwlam, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2013). Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(1), pp. 239-250. Elsevier 10.1016/j.bbalip.2012.07.022

Koch, Alexander; Pfeilschrifter, Josef; Huwiler, Andrea (2013). Sphingosine 1-phosphate in renal diseases. Cellular physiology and biochemistry, 31(6), pp. 745-760. Karger 10.1159/000350093

Simon, Manuel; Frey, Raphael; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2013). Orthogonal assembly of a designed ankyrin repeat protein-cytotoxin conjugate with a clickable serum albumin module for half-life extension. Bioconjugate chemistry, 24(11), pp. 1955-1986. American Chemical Society 10.1021/bc4004102

Simon, Manuel; Stefan, Nikolas; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2013). Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy. Expert opinion on drug delivery, 10(4), pp. 451-468. Taylor & Francis 10.1517/17425247.2013.759938

Walter, Stephen D.; Riddell, Corinne A.; Rabachini, Tatiana; Villa, Luisa L.; Franco, Eduardo L. (2013). Accuracy of p53 codon 72 polymorphism status determined by multiple laboratory methods: a latent class model analysis. PLoS ONE, 8(2), e56430. Public Library of Science 10.1371/journal.pone.0056430

Hajj, Glaucia N. M.; Arantes, Camilla P.; Dias, Marcos Vinicios; Roffé, Martin; Silva, Bruno Costa; Lopes, Marilene H.; Porto-Carreiro, Isabel; Rabachini de Almeida, Tatiana; Lima, Flavia R.; Beraldo, Flavio H.; Prado, Marco M. A.; Linden, Rafael; Martins, Vilma R. (2013). The unconventional secretion of stress-inducible protein 1 by a heterogeneous population of extracellular vesicles. Cellular and molecular life sciences, 70(17), pp. 3211-3227. Springer 10.1007/s00018-013-1328-y

Chevarie-Davis, M.; Ramanakumar, A. V.; Ferenczy, A.; Villa, L. L.; Franco, E. L.; Rabachini de Almeida, Tatiana (2013). Assessment of the performance of algorithms for cervical cancer screening: evidence from the Ludwig-McGill cohort study. Gynecologic oncology, 128(3), pp. 415-419. Elsevier 10.1016/j.ygyno.2012.12.008

Rabachini de Almeida, Tatiana; Oliveira, LB; Louvanto, K; Ramanakumar, AV; Franco, EL; Villa, L.L. (2013). Polymorphism in the promoter region of the Toll-like receptor 9 gene and cervical human papillomavirus infection. Journal of general virology, 94(8), pp. 1858-1864. Society for General Microbiology 10.1099/vir.0.052811-0

Stoeckle, C.; Simon, Hans-Uwe (2013). CD8(+) T cells producing IL-3 and IL-5 in non-IgE-mediated eosinophilic diseases. Allergy, 68(12), pp. 1622-1628. Wiley-Blackwell 10.1111/all.12311

Simon, D.; Straumann, A.; Dahinden, C.; Simon, H.-U. (2013). Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis. Allergy, 68(7), pp. 945-948. Wiley-Blackwell 10.1111/all.12157

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4, p. 2130. Nature Publishing Group 10.1038/ncomms3130

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2013). Targeting autophagy as a potential therapeutic approach for melanoma therapy. Seminars in Cancer Biology, 5(23), pp. 352-360. Elsevier 10.1016/j.semcancer.2013.06.008

Henzi, Anna; Porz, Nicole; Widmer, Hans Rudolf; Di Santo, Stefano (2013). EPC secretome promotes neurogenesis in rat brain: New tool for brain repair? In: Annual Meeting of the Department of Clinical Research. Bern.

Simon, Dagmar; Simon, Hans-Uwe (2013). Eosinophilic skin diseases. In: Lee, James J.; Rosenberg, Helene F. (eds.) Eosinophils in health and diseases (pp. 442-448). Amsterdam: Elsevier

Worni, Mathias; Güller, Ulrich; White, Rebekah R.; Castleberry, Anthony W.; Pietrobon, Ricardo; Cerny, Thomas; Gloor, Beat; Köberle, Dieter (2013). Modest Improvement in Overall Survival for Patients With Metastatic Pancreatic Cancer. Pancreas, 42(7), pp. 1157-1163. Lippincott Williams & Wilkins 10.1097/MPA.0b013e318291fbc5

Konstantinidou, Georgia; Ramadori, Giorgio; Torti, Francesca; Kangasniemi, Kim; Ramirez, Rachel E.; Cai, Yiran; Behrens, Carmen; Dellinger, Michael T.; Brekken, Rolf A.; Wistuba, Ignacio I.; Heguy, Adriana; Teruya-Feldstein, Julie; Scaglioni, Pier Paolo (2013). RHOA-FAK Is a Required Signaling Axis for the Maintenance of KRAS-Driven Lung Adenocarcinomas. Cancer discovery, 3(4), pp. 444-457. American Association for Cancer Research 10.1158/2159-8290.CD-12-0388

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3, e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Kotelevets, Nataliya; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2012). Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. PLoS ONE, 7(6), e39209. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0039209

Heine, Markus; Freund, Barbara; Nielsen, Peter; Jung, Caroline; Reimer, Rudolph; Hohenberg, Heinrich; Zangemeister-Wittke, Uwe; Wester, Hans-Juergen; Lüers, Georg H; Schumacher, Udo (2012). High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes. PLoS ONE, 7(5), e36258. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0036258

Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2012). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer (pp. 2437-2440). Heidelberg: Springer-Verlage 10.1007/978-3-642-16483-5

Rabellino, A.; Carter, B.; Konstantinidou, Georgia; Wu, S.-Y.; Rimessi, A.; Byers, L. A.; Heymach, J. V.; Girard, L.; Chiang, C.-M.; Teruya-Feldstein, J.; Scaglioni, P. P. (2012). The SUMO E3-ligase PIAS1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA. Cancer research, 72(9), pp. 2275-2284. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-11-3159

Scaglioni, Pier Paolo; Rabellino, Andrea; Yung, Thomas M.; Bernardi, Rosa; Choi, Sooyeon; Konstantinidou, Georgia; Nardella, Caterina; Cheng, Ke; Pandolfi, Pier Paolo (2012). Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence. EMBO molecular medicine, 4(7), pp. 594-602. EMBO Press 10.1002/emmm.201200233

Bisaro, Brigitte; Montani, Maura; Konstantinidou, Georgia; Marchini, Cristina; Pietrella, Lucia; Iezzi, Manuela; Galiè, Mirco; Orso, Francesca; Camporeale, Annalisa; Colombo, Shana M; Di Stefano, Paola; Tornillo, Giusy; Camacho-Leal, Maria P; Turco, Emilia; Taverna, Daniela; Cabodi, Sara; Amici, Augusto; Defilippi, Paola (2012). p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells. Breast cancer research, 14(5), R137. BioMed Central Ltd. 10.1186/bcr3342

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2, e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Patricia, Martin-Killias; Stefan, Nikolas; Rothschild, Sacha; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2011). A novel fusion toxin derived from an EpCAM-specific designed ankyrin repeat protein has potent antitumor activity. Clinical cancer research, 17(1), pp. 100-10. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-10-1303

Huwiler, Andrea; Bourquin, Florence; Kotelevets, Nataliya; Pastukhov, Oleksandr; Capitani, Guido; Grütter, Markus G; Zangemeister-Wittke, Uwe (2011). A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders. PLoS ONE, 6(8), e22436. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022436

Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206

Casulli, Sarah; Topçu, Selma; Fattoum, Lakhdar; von Gunten, Stephan; Simon, Hans-Uwe; Teillaud, Jean-Luc; Bayry, Jagadeesh; Kaveri, Srini V.; Elbim, Carole (2011). A differential concentration-dependent effect of IVIg on neutrophil functions: relevance for anti-microbial and anti-inflammatory mechanisms. PLoS ONE, 6(10), e26469. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026469

Hruz, Petr; Straumann, Alex; Bussmann, Christian; Heer, Pius; Simon, Hans-Uwe; Zwahlen, Marcel; Beglinger, Christoph; Schoepfer, Alain M (2011). Escalating incidence of eosinophilic esophagitis: a 20-year prospective, population-based study in Olten County, Switzerland. Journal of allergy and clinical immunology, 128(6), 1349-1350.e5. St. Louis, Mo.: Mosby 10.1016/j.jaci.2011.09.013

Bousquet, Jean; Anto, Josep M; Sterk, Peter J; Adcock, Ian M; Chung, Kian Fan; Roca, Josep; Agusti, Alvar; Brightling, Chris; Cambon-Thomsen, Anne; Cesario, Alfredo; Abdelhak, Sonia; Antonarakis, Stylianos E; Avignon, Antoine; Ballabio, Andrea; Baraldi, Eugenio; Baranov, Alexander; Bieber, Thomas; Bockaert, Joël; Brahmachari, Samir; Brambilla, Christian; ... (2011). Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome medicine, 3(7), p. 43. London: BioMed Central 10.1186/gm259

Bieber, T; Simon, H-U (2011). Allergen-specific immunotherapy: current concepts and future directions. Allergy, 66(6), pp. 709-12. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02595.x

El-Hashim, Ahmed; Yousefi, Shida; Edafiogho, Ivan; Raghupathy, Raj; Yousif, Mariam; Simon, Hans-Uwe (2010). Anti-inflammatory and immunosuppressive effects of the enaminone E121. European journal of pharmacology, 632(1-3), pp. 73-78. Amsterdam: Elsevier 10.1016/j.ejphar.2009.12.004

Schoepfer, Alain M; Gonsalves, Nirmala; Bussmann, Christian; Conus, Sébastien; Simon, Hans-Uwe; Straumann, Alex; Hirano, Ikuo (2010). Esophageal Dilation in Eosinophilic Esophagitis: Effectiveness, Safety, and Impact on the Underlying Inflammation. American journal of gastroenterology, 105(5), pp. 1062-1070. New York, N.Y.: Nature 10.1038/ajg.2009.657

Jost, Philipp J; Kaufmann, Thomas (2010). Cancer caused by too much apoptosis--an intriguing contradiction? Hepatology, 51(4), pp. 1110-1112. Hoboken, N.J.: Wiley Interscience 10.1002/hep.23314

von Gunten, Stephan; Simon, Hans-Uwe (2010). Cell death modulation by intravenous immunoglobulin. Journal of clinical immunology, 30 Suppl 1, S24-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10875-010-9411-8

Derré, Laurent; Jandus, Camilla; Baumgaertner, Petra; Posevitz, Vilmos; Devêvre, Estelle; Romero, Pedro; Speiser, Daniel E (2010). Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses. Methods in molecular biology, 626, pp. 231-249. Totowa, N.J.: Humana Press 10.1007/978-1-60761-585-9_16

Bieber, T; Simon, H-U (2010). Shaping the future of Allergy. Allergy, 65(1), p. 1. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.02272.x

Marchini, Cristina; Montani, Maura; Konstantinidou, Georgia; Orrù, Rita; Mannucci, Silvia; Ramadori, Giorgio; Gabrielli, Federico; Baruzzi, Anna; Berton, Giorgio; Merigo, Flavia; Fin, Stefania; Iezzi, Manuela; Bisaro, Brigitte; Sbarbati, Andrea; Zerani, Massimo; Galiè, Mirco; Amici, Augusto; Shioda, Toshi (2010). Mesenchymal/Stromal Gene Expression Signature Relates to Basal-Like Breast Cancers, Identifies Bone Metastasis and Predicts Resistance to Therapies. PLoS ONE, 5(11), e14131. Public Library of Science 10.1371/journal.pone.0014131

Jost, Philipp J; Grabow, Stephanie; Gray, Daniel; McKenzie, Mark D; Nachbur, Ueli; Huang, David C S; Bouillet, Philippe; Thomas, Helen E; Borner, Christoph; Silke, John; Strasser, Andreas; Kaufmann, Thomas (2009). XIAP discriminates between type I and type II FAS-induced apoptosis. Nature, 460(7258), pp. 1035-1039. London: Macmillan Journals Ltd. 10.1038/nature08229

Bianchi, K; Jost, P J; Kaufmann, T; Rutkowski, R (2009). International EMBO Workshop on 'Model Organisms in Cell Death Research', Obergurgl (Austria). Cell death and differentiation, 16(8), pp. 1180-3. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.60

Jabbour, A M; Heraud, J E; Daunt, C P; Kaufmann, T; Sandow, J; O'Reilly, L A; Callus, B A; Lopez, A; Strasser, A; Vaux, D L; Ekert, P G (2009). Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation, 16(4), pp. 555-63. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.179

Marinov, Marin; Ziogas, Algirdas; Pardo, Olivier E; Tan, Liwen Terence; Dhillon, Tony; Mauri, Francesco A; Lane, Heidi A; Lemoine, Nicholas R; Zangemeister-Wittke, Uwe; Seckl, Michael J; Arcaro, Alexandre (2009). AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001. Clinical cancer research, 15(4), pp. 1277-87. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-2166

von Gunten, Stephan; Bochner, Bruce S (2009). Expression and Function of Siglec-8 in Human Eosinophils, Basophils, and Mast Cells. In: Pawankar, Ruby; Holgate, Stephen T; Rosenwasser, Lanny J (eds.) Allergy Frontiers: Classification and Pathomechanisms. Allergy Frontiers: Vol. 2 (pp. 297-313). Japan: Springer 10.1007/978-4-431-88315-9_19

Stoeckle, Christina; Gleske, Anne-Kathrin (2009). Immunotherapy: from basic research to clinical applications. Cancer immunology, immunotherapy, 58(7), pp. 1129-36. Heidelberg: Springer 10.1007/s00262-008-0544-z

Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cells of the blood. Biochimica and biophysica acta - molecular and cell biology of lipids, 1793(9), pp. 1461-4. New York, N.Y.: Elsevier 10.1016/j.bbamcr.2008.12.023

Simon, Hans-Uwe (2009). Cell death in allergic diseases. Apoptosis, 14(4), pp. 439-46. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10495-008-0299-1

Andina, N; Didichenko, S; Schmidt-Mende, J; A.Dahinden, C.; Simon, Hans-Uwe (2009). Pim-1 but not PI3K is essential in the anti-apoptotic signalling casdace initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, pp. 603-611. St. Louis, Mo.: Mosby

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Konstantinidou, Georgia; Bey, E. A.; Rabellino, A.; Schuster, K.; Maira, M. S.; Gazdar, A. F.; Amici, A.; Boothman, D. A.; Scaglioni, P. P. (2009). Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Blockade Is an Effective Radiosensitizing Strategy for the Treatment of Non-Small Cell Lung Cancer Harboring K-RAS Mutations. Cancer research, 69(19), pp. 7644-7652. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-09-0823

Belyanskaya, Larisa L; Ziogas, Algirdas; Hopkins-Donaldson, Sally; Kurtz, Stefanie; Simon, Hans-Uwe; Stahel, Rolf; Zangemeister-Wittke, Uwe (2008). TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8. Lung cancer, 60(3), pp. 355-65. Amsterdam: Elsevier 10.1016/j.lungcan.2007.11.005

Rothenberg, Marc E; Klion, Amy D; Roufosse, Florence E; Kahn, Jean Emmanuel; Weller, Peter F; Simon, Hans-Uwe; Schwartz, Lawrence B; Rosenwasser, Lanny J; Ring, Johannes; Griffin, Elaine F; Haig, Ann E; Frewer, Paul I H; Parkin, Jacqueline M; Gleich, Gerald J (2008). Treatment of patients with the hypereosinophilic syndrome with mepolizumab. New England journal of medicine NEJM, 358(12), pp. 1215-28. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMoa070812

Constantinou, Thecla; Baumann, Fabrizio; Lacher, Markus D; Saurer, Susanne; Friis, Robert; Dharmarajan, Arun (2008). SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation. Journal of molecular signaling, 3, p. 10. London: BioMed Central 10.1186/1750-2187-3-10

Scaglioni, P. P.; Yung, T. M.; Choi, S. C.; Baldini, C.; Konstantinidou, Georgia; Pandolfi, P. P. (2008). CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor. Molecular and cellular biochemistry, 316(1-2), pp. 149-154. Springer 10.1007/s11010-008-9812-7

Galiè, M; Konstantinidou, Georgia; Peroni, D; Scambi, I; Marchini, C; Lisi, V; Krampera, M; Magnani, P; Merigo, F; Montani, M; Boschi, F; Marzola, P; Orrù, R; Farace, P; Sbarbati, A; Amici, A (2008). Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice. Oncogene, 27(18), pp. 2542-2551. Nature Publishing Group 10.1038/sj.onc.1210920

Simon, D; Braathen, L R; Simon, H-U (2007). [Anti-interleukin-5 therapy for eosinophilic diseases]. Hautarzt, 58(2), 122, 124-7. Heidelberg: Springer-Verlag 10.1007/s00105-006-1273-x

Zangemeister-Wittke, Uwe (2007). Antisense molecules for targeted cancer therapy. Onkologe, 13(3), pp. 256-262. Springer-Medizin-Verlag 10.1007/s00761-006-1170-z

Zangemeister-Wittke, Uwe; Huwiler, Andrea (2006). Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer. Cancer biology & therapy, 5(10), pp. 1355-1356. Georgetown, Tex.: Landes Bioscience 10.4161/cbt.5.10.3488

Huwiler, Andrea; Döll, Frauke; Ren, Shuyu; Klawitter, Sabine; Greening, Anna; Römer, Isolde; Bubnova, Svetlana; Reinsberg, Luise; Pfeilschifter, Josef (2006). Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism. Biochimica and biophysica acta - molecular and cell biology of lipids, 1761(3), pp. 367-376. Biochimica and biophysica acta - molecular and cell biology of lipids: Elsevier 10.1016/j.bbalip.2006.02.007

Simon, Hans-Uwe (2006). Cytokine and anti-cytokine therapy for asthma. Current allergy and asthma reports, 6(2), pp. 117-21. Philadelphia, Pa.: Springer 10.1007/s11882-006-0049-9

Wacheck, V; Zangemeister-Wittke, Uwe (2006). Antisense molecules for targeted cancer therapy. Critical reviews in oncology, hematology, 59(1), pp. 65-73. Boca Raton, Fla.: Elsevier 10.1016/j.critrevonc.2005.10.004

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Urbanczik, R.; Wagner, C. (2005). Functional stoichiometric analysis of metabolic networks. Bioinformatics, 21(22), pp. 4176-4180. Oxford University Press 10.1093/bioinformatics/bti674

Urbanczik, R.; Wagner, C. (2005). An improved algorithm for stoichiometric network analysis: theory and applications. Bioinformatics, 21(7), pp. 1203-1210. Oxford University Press 10.1093/bioinformatics/bti127

Bircher, Johannes (2005). Towards a Dynamic Definition of Health and Disease. Medicine, health care and philosophy, 8(3), pp. 335-341. Kluwer Academic Publishers 10.1007/s11019-005-0538-y

Reinhardt, Didier; Pesce, Eva-Rachele; Stieger, Pia; Mandel, Therese; Baltensperger, Kurt; Bennett, Malcolm; Traas, Jan; Friml, Jiří; Kuhlemeier, Cris (2003). Regulation of phyllotaxis by polar auxin transport. Nature, 426(6964), pp. 255-260. Macmillan Journals Ltd. 10.1038/nature02081

Betticher, D. C.; Zucca, E.; Von Rohr, A.; Egger, T.; Radford, J. A.; Ambrosetti, A.; Bürki, K.; Rufener, B.; Hsu Schmitz, S. F.; Cerny, Thomas (1996). 2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III–IV non-Hodgkin's lymphoma. Annals of oncology, 7(8), pp. 793-799. Oxford University Press 10.1093/oxfordjournals.annonc.a010757

Hammon, Harald M.; Bruckmaier, Rupert M.; Honegger, Ulrich E.; Blum, Jürg W. (1994). Distribution and density of α– and β–adrenergic receptor binding sites in the bovine mammary gland. Journal of dairy research, 61(1), pp. 47-57. Cambridge University Press 10.1017/S0022029900028041

Peter, Andreas B.; Schittny, Johannes C.; Niggli, Verena; Reuter, Harald; Sigel, Erwin (1991). The polarized distribution of poly(A+)-mRNA-induced functional ion channels in the Xenopus oocyte plasma membrane is prevented by anticytoskeletal drugs. Journal of cell biology, 114(3), pp. 455-464. Rockefeller Institute Press

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