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Abd El Hafez, Mai Moustafa Ahmed

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Adams, Olivia Joan

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Human IgA binds a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.20181635

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Correction: Human IgA bind a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.2018163501152020c

Adams, Olivia Joan; von Gunten, Stephan (2018). Recent Advances in Experimental Allergy. International archives of allergy and immunology, 177(4), pp. 281-289. Karger 10.1159/000494440

Aeschlimann, Salome

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Alves, Marco

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Amini, Poorya

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Amini, Poorya (2016). Optic atrophy 1 (OPA1) is essential for NET formation and antibacterial functions in neutrophils (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, Faculty of Medicine, University of Bern)

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Andina, Nicola

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Andreasi, Valentina

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Angelillo, Anne

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

April, Simon

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

April-Monn, Simon

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Arcaro, Alexandre

Wojtalla, Anna; Fischer, Barbara; Kotelevets, Nataliya; Mauri, Francesco A; Sobek, Jens; Rehrauer, Hubert; Wotzkow, Carlos; Tschan, Mario P; Seckl, Michael J; Zangemeister-Wittke, Uwe; Arcaro, Alexandre (2013). Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clinical cancer research, 19(1), pp. 96-105. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-1138

Marinov, Marin; Ziogas, Algirdas; Pardo, Olivier E; Tan, Liwen Terence; Dhillon, Tony; Mauri, Francesco A; Lane, Heidi A; Lemoine, Nicholas R; Zangemeister-Wittke, Uwe; Seckl, Michael J; Arcaro, Alexandre (2009). AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001. Clinical cancer research, 15(4), pp. 1277-87. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-2166

Aujesky, Drahomir

Spirk, David; Sebastian, Tim; Beer, Jürg Hans; Mazzolai, Lucia; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf Peter; Korte, Wolfgang; Kucher, Nils; Barco, Stefano (2022). Role of age, sex, and specific provoking factors on the distal versus proximal presentation of first symptomatic deep vein thrombosis: analysis of the SWIss Venous ThromboEmbolism Registry (SWIVTER). Internal and emergency medicine, 17(3), pp. 799-803. Springer 10.1007/s11739-021-02878-7

Spirk, David; Sebastian, Tim; Barco, Stefano; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Blondon, Marc; Kucher, Nils (2021). Clinical Outcomes of Incidental Venous Thromboembolism in Cancer and Noncancer Patients: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 121(5), pp. 641-649. Thieme 10.1055/s-0040-1720977

Spirk, David; Sebastian, Tim; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Mollet, Annette; Szucs, Thomas D; Kucher, Nils (2019). Venous Thromboembolism and Renal Impairment: Insights from the SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 45(8), pp. 851-858. Thieme Medical Publishers 10.1055/s-0039-1698770

Blondon, Marc; Spirk, David; Kucher, Nils; Aujesky, Drahomir; Hayoz, Daniel; Beer, Jürg H; Husmann, Marc; Frauchiger, Beat; Korte, Wolfgang; Wuillemin, Walter Alfred; Bounameaux, Henri; Righini, Marc; Nendaz, Mathieu (2018). Comparative Performance of Clinical Risk Assessment Models for Hospital-Acquired Venous Thromboembolism in Medical Patients. Thrombosis and haemostasis, 118(1), pp. 82-89. Schattauer 10.1160/TH17-06-0403

Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086

Spirk, David; Stuck, Anna K.; Hager, A; Engelberger, Rolf P.; Aujesky, Drahomir; Kucher, Nils (2017). Electronic alert system for improving appropriate thromboprophylaxis in hospitalized medical patients: a randomized controlled trial. Journal of thrombosis and haemostasis, 15(11), pp. 2138-2146. Wiley-Blackwell 10.1111/jth.13812

Spirk, David; Aujesky, Drahomir; Stuck, Anna K; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Kucher, Nils (2016). Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 42(6), pp. 642-649. Thieme Medical Publishers 10.1055/s-0036-1584131

Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Spirk, David (2016). Rivaroxaban for the treatment of venous thromboembolism. The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 116(3), pp. 472-479. Schattauer 10.1160/TH16-03-0209

Spirk, David; Nendaz, M; Aujesky, Drahomir; Hayoz, D; Beer, J H; Husmann, M; Frauchiger, B; Korte, W; Wuillemin, Walter Alfred; Righini, M; Bounameaux, H; Kucher, Nils (2015). Predictors of thromboprophylaxis in hospitalised medical patients. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE). Thrombosis and haemostasis, 113(5), pp. 1127-1134. Schattauer 10.1160/TH14-06-0525

Bachmann, Daniel

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116

Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008

Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Bachmann, Martin

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Simon, Hans-Uwe; Karaulov, Alexander V; Bachmann, Martin F. (2020). Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection. International archives of allergy and immunology, 181(8), pp. 624-628. Karger 10.1159/000509368

Badmann, Anastasia

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3, e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2, e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Baerlocher, Gabriela M.

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Baltensperger, Kurt

Reinhardt, Didier; Pesce, Eva-Rachele; Stieger, Pia; Mandel, Therese; Baltensperger, Kurt; Bennett, Malcolm; Traas, Jan; Friml, Jiří; Kuhlemeier, Cris (2003). Regulation of phyllotaxis by polar auxin transport. Nature, 426(6964), pp. 255-260. Macmillan Journals Ltd. 10.1038/nature02081

Barut, G Tuba

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Basaco Bernabeu, Tais

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Baumann, Christa Katharina

Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692

Baumgartner, Iris

Sebastian, Tim; Barco, Stefano; Engelberger, Rolf P; Spirk, David; Schindewolf, Marc; Baumann, Frederic; Baumgartner, Iris; Kucher, Nils (2020). Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. European journal of vascular and endovascular surgery EJVES, 60(3), pp. 443-450. Elsevier 10.1016/j.ejvs.2020.05.011

Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086

Engelberger, Rolf P.; Stuck, Anna; Spirk, David; Willenberg, Torsten; Haine, Axel; Périard, Daniel; Baumgartner, Iris; Kucher, Nils (2017). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute ilio-femoral deep vein thrombosis: one-year follow-up data of a randomized-controlled trial. Journal of thrombosis and haemostasis, 15(7), pp. 1351-1360. Wiley-Blackwell 10.1111/jth.13709

Spirk, David; Aujesky, Drahomir; Stuck, Anna K; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Kucher, Nils (2016). Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 42(6), pp. 642-649. Thieme Medical Publishers 10.1055/s-0036-1584131

Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Spirk, David (2016). Rivaroxaban for the treatment of venous thromboembolism. The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 116(3), pp. 472-479. Schattauer 10.1160/TH16-03-0209

Silbernagel, Günther; Spirk, David; Hager, Adrian; Baumgartner, Iris; Kucher, Nils (2016). Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial. Journal of the American Heart Association, 5(7), pp. 1-7. American Heart Association 10.1161/JAHA.116.003776

Engelberger, Rolf Peter; Spirk, David; Willenberg, Torsten Andreas; Alatri, Adriano; Do, Dai-Do; Baumgartner, Iris; Kucher, Nils (2015). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Circulation: Cardiovascular interventions, 8(1) Lippincott Williams & Wilkins 10.1161/CIRCINTERVENTIONS.114.002027

Baumgartner, Johanna Maria Magdalena

Saliakoura, Maria; Rossi, Sebastiano Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Baumgartner, Stephan

Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2008). Test System Stability and Natural Variability of a Lemna Gibba L. Bioassay. PLoS ONE, 3(9), e3133. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0003133

Baumgartner, Susanne-Esther

Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2009). Effects of potentised substances on growth rate of the water plant Lemna gibba L. Complementary therapies in medicine, 17(2), pp. 63-70. Exeter: Elsevier 10.1016/j.ctim.2008.10.004

Beldi, Guido

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Beltraminelli, Helmut

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

Benarafa, Charaf

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Burgener, Sabrina Sofia; Brügger, Melanie; Leborgne, Nathan Georges François; Sollberger, Sophia; Basilico, Paola; Kaufmann, Thomas; Bird, Phillip Ian; Benarafa, Charaf (2021). Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. Frontiers in cell and developmental biology, 9, p. 630166. Frontiers 10.3389/fcell.2021.630166

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Benarafa, Charaf; Simon, Hans-Uwe (2017). Role of granule proteases in the life and death of neutrophils. Biochemical and biophysical research communications, 482(3), pp. 473-481. Academic Press 10.1016/j.bbrc.2016.11.086

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Berezowska, Sabina Anna

Saliakoura, Maria; Rossi, Sebastiano Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Betticher, Daniel

Betticher, D. C.; Zucca, E.; Von Rohr, A.; Egger, T.; Radford, J. A.; Ambrosetti, A.; Bürki, K.; Rufener, B.; Hsu Schmitz, S. F.; Cerny, Thomas (1996). 2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III–IV non-Hodgkin's lymphoma. Annals of oncology, 7(8), pp. 793-799. Oxford University Press 10.1093/oxfordjournals.annonc.a010757

Bill, Anna Magdalena

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Blanchard, Olivier

Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Blum, Jürg

Hammon, Harald M.; Bruckmaier, Rupert M.; Honegger, Ulrich E.; Blum, Jürg W. (1994). Distribution and density of α– and β–adrenergic receptor binding sites in the bovine mammary gland. Journal of dairy research, 61(1), pp. 47-57. Cambridge University Press 10.1017/S0022029900028041

Bohlender, Jürgen

Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488

Bologna, Luca

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Borradori, Luca

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2013). Glucocorticoids in autoimmune bullous diseases: are neutrophils the key cellular target? Journal of Investigative Dermatology, 133(10), pp. 2314-2315. Nature Publishing 10.1038/jid.2013.205

Bouchet, Audrey Michele

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Bovet, Cédric

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Braathen, Lasse Roger

Simon, D; Straumann, A; Wenk, A; Spichtin, H; Simon, H-U; Braathen, L R (2006). Eosinophilic esophagitis in adults--no clinical relevance of wheat and rye sensitizations. Allergy, 61(12), pp. 1480-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01224.x

Simon, Dagmar; Lindberg, Raija L P; Kozlowski, Evelyne; Braathen, Lasse R; Simon, Hans-Uwe (2006). Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions. Experimental dermatology, 15(6), pp. 441-6. Oxford: Blackwell 10.1111/j.0906-6705.2006.00428.x

Brandl, Fabian

Brandl, Fabian; Busslinger, Sarah; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2020). Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life. Journal of controlled release, 327, pp. 186-197. Elsevier 10.1016/j.jconrel.2020.08.004

Brandl, Fabian; Merten, Hannes; Zimmermann, Martina; Béhé, Martin; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins. Journal of controlled release, 307, pp. 379-392. Elsevier 10.1016/j.jconrel.2019.06.030

Lorenzer, Cornelia; Streußnig, Sonja; Tot, Emilia; Winkler, Anna-Maria; Merten, Hannes; Brandl, Fabian; Sayers, Edward J; Watson, Peter; Jones, Arwyn T; Zangemeister-Wittke, Uwe; Plückthun, Andreas; Winkler, Johannes (2019). Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing. European journal of pharmaceutics and biopharmaceutics, 141, pp. 37-50. Elsevier 10.1016/j.ejpb.2019.05.015

Merten, Hannes; Schaefer, Jonas V; Brandl, Fabian; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Facile Site-Specific Multiconjugation Strategies in Recombinant Proteins Produced in Bacteria. Methods in molecular biology, 2033, pp. 253-273. Springer 10.1007/978-1-4939-9654-4_17

Merten, Hannes; Brandl, Fabian; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2015). Antibody-Drug Conjugates for Tumor Targeting-Novel Conjugation Chemistries and the Promise of non-IgG Binding Proteins. Bioconjugate chemistry, 26(11), pp. 2176-2185. American Chemical Society 10.1021/acs.bioconjchem.5b00260

Brigger, Daniel

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010

Britschgi, Adrian

Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Bruckmaier, Rupert

Hammon, Harald M.; Bruckmaier, Rupert M.; Honegger, Ulrich E.; Blum, Jürg W. (1994). Distribution and density of α– and β–adrenergic receptor binding sites in the bovine mammary gland. Journal of dairy research, 61(1), pp. 47-57. Cambridge University Press 10.1017/S0022029900028041

Brunner, Thomas

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3, e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2, e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Kassahn, D; Nachbur, U; Conus, S; Micheau, O; Schneider, P; Simon, H-U; Brunner, T (2009). Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell death and differentiation, 16(1), pp. 115-24. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.133

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Nachbur, Ueli; Kassahn, Daniela; Yousefi, Shida; Legler, Daniel F; Brunner, Thomas (2006). Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts. Blood, 107(7), pp. 2790-6. Washington, D.C.: American Society of Hematology 10.1182/blood-2005-07-2744

Brönnimann, Daniel

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Brügger, Melanie

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Burgener, Sabrina Sofia; Brügger, Melanie; Leborgne, Nathan Georges François; Sollberger, Sophia; Basilico, Paola; Kaufmann, Thomas; Bird, Phillip Ian; Benarafa, Charaf (2021). Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. Frontiers in cell and developmental biology, 9, p. 630166. Frontiers 10.3389/fcell.2021.630166

Bucher, Jan Rudolf

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Buri, Michelle Claudine

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Burkhalter, Sophie

Rollenske, Tim; Burkhalter, Sophie; Muerner, Lukas; von Gunten, Stephan; Lukasiewicz, Jolanta; Wardemann, Hedda; Macpherson, Andrew J. (2021). Parallelism of intestinal secretory IgA shapes functional microbial fitness. Nature, 598(7882), pp. 657-661. Springer Nature 10.1038/s41586-021-03973-7

Bär, Sarah

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Bürgi, Sibylle

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Bürgler, Christina

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Bürki, Kurt

Betticher, D. C.; Zucca, E.; Von Rohr, A.; Egger, T.; Radford, J. A.; Ambrosetti, A.; Bürki, K.; Rufener, B.; Hsu Schmitz, S. F.; Cerny, Thomas (1996). 2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III–IV non-Hodgkin's lymphoma. Annals of oncology, 7(8), pp. 793-799. Oxford University Press 10.1093/oxfordjournals.annonc.a010757

Bütikofer, Peter

Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356

Büttiker, Urs

Simon, Dagmar; Wittwer, Jennifer; Kostylina, Ganna; Buettiker, Urs; Simon, Hans-Uwe; Yawalkar, Nikhil (2008). Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema. Journal of allergy and clinical immunology, 122(2), pp. 423-4. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.010

Calzavarini, Sara

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Cazzaniga, Simone

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Cerny, Thomas

Betticher, D. C.; Zucca, E.; Von Rohr, A.; Egger, T.; Radford, J. A.; Ambrosetti, A.; Bürki, K.; Rufener, B.; Hsu Schmitz, S. F.; Cerny, Thomas (1996). 2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III–IV non-Hodgkin's lymphoma. Annals of oncology, 7(8), pp. 793-799. Oxford University Press 10.1093/oxfordjournals.annonc.a010757

Chan, Andrew

Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992

Christen, Stephan

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Claus, Meike Janina

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Constantinescu, Mihai Adrian

Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200

Conus, Sébastien

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

Schoepfer, Alain M; Gonsalves, Nirmala; Bussmann, Christian; Conus, Sébastien; Simon, Hans-Uwe; Straumann, Alex; Hirano, Ikuo (2010). Esophageal Dilation in Eosinophilic Esophagitis: Effectiveness, Safety, and Impact on the Underlying Inflammation. American journal of gastroenterology, 105(5), pp. 1062-1070. New York, N.Y.: Nature 10.1038/ajg.2009.657

Straumann, Alex; Conus, Sebastien; Degen, Lukas; Felder, Stephanie; Kummer, Mirjam; Engel, Hansjürg; Bussmann, Christian; Beglinger, Christoph; Schoepfer, Alain; Simon, Hans-Uwe (2010). Budesonide is effective in adolescent and adult patients with active eosinophilic esophagitis. Gastroenterology, 139(5), 1526-37, 1537.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2010.07.048

Conus, Sébastien; Straumann, Alex; Bettler, Eva; Simon, Hans-Uwe (2010). Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis. Journal of allergy and clinical immunology, 126(1), pp. 175-7. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.04.029

Straumann, A; Conus, S; Grzonka, P; Kita, H; Kephart, G; Bussmann, C; Beglinger, C; Smith, D A; Patel, J; Byrne, M; Simon, H-U (2010). Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: a randomised, placebo-controlled, double-blind trial. Gut, 59(1), pp. 21-30. London: BMJ Publishing Group 10.1136/gut.2009.178558

Conus, Sébastien; Perozzo, Remo; Reinheckel, Thomas; Peters, Christoph; Scapozza, Leonardo; Yousefi, Shida; Simon, Hans-Uwe (2008). Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. Journal of experimental medicine, 205(3), pp. 685-698. New York, N.Y.: Rockefeller University Press 10.1084/jem.20072152

Corazza, Nadia

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3, e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Corazza, Nadia; Kaufmann, Thomas (2012). Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models. Allergy, 67(12), pp. 1483-90. Oxford: Wiley-Blackwell 10.1111/all.12065

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2, e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Courage, Carolina

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Dahinden, Clemens A.

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Simon, D.; Straumann, A.; Dahinden, C.; Simon, H.-U. (2013). Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis. Allergy, 68(7), pp. 945-948. Wiley-Blackwell 10.1111/all.12157

Daryadel, Arezoo; Yousefi, Shida; Troi, David; Schmid, Inès; Schmidt-Mende, Jan; Mordasini, Carlo; Dahinden, Clemens A; Ziemiecki, Andrew; Simon, Hans-Uwe (2009). RhoH/TTF negatively regulates leukotriene production in neutrophils. Journal of immunology, 182(10), pp. 6527-32. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803846

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Daudel, Fritz

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/​jimmunol.1400028

De Brot, Simone Danielle

Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

De Marchis, Gian Marco

De Marchis, Gian Marco; Bürgi, Sibylle; Kientsch, Urs; Honegger, Ulrich E (2006). Vitamin E reduces antidepressant-related beta-adrenoceptor down-regulation in cultured cells. Comparable effects on St. John's wort and tricyclic antidepressant treatment. Planta medica, 72(15), pp. 1436-7. Stuttgart: Thieme 10.1055/s-2006-951727

Degen, Martin

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Deladoëy, Johnny

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Salemi, Souzan; Yousefi, Shida; Eblé, Andrée; Deladoëy, Johnny; Mullis, Primus E (2006). Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis. Hormone research, 65(3), pp. 132-41. Basel: Karger 10.1159/000091607

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Demoulins, Thomas

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Deng, Haibin

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Despont, Alain

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Dewarrat, Natacha

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Di Domenico, Annunziata

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Di Santo, Stefano

Henzi, Anna; Porz, Nicole; Widmer, Hans Rudolf; Di Santo, Stefano (2013). EPC secretome promotes neurogenesis in rat brain: New tool for brain repair? In: Annual Meeting of the Department of Clinical Research. Bern.

Dickgreber, Nina

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Didichenko, Svetlana

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Djonov, Valentin Georgiev

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/​jimmunol.1400028

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Do, Dai-Do

Engelberger, Rolf Peter; Spirk, David; Willenberg, Torsten Andreas; Alatri, Adriano; Do, Dai-Do; Baumgartner, Iris; Kucher, Nils (2015). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Circulation: Cardiovascular interventions, 8(1) Lippincott Williams & Wilkins 10.1161/CIRCINTERVENTIONS.114.002027

Dopheide, Jörn Fredrik

Sebastian, Tim; Spirk, David; Engelberger, Rolf P; Dopheide, Jörn F.; Baumann, Frederic A; Barco, Stefano; Spescha, Rebecca; Leeger, Claudia; Kucher, Nils (2019). Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome. Thrombosis and haemostasis, 119(12), pp. 2064-2073. Thieme 10.1055/s-0039-1697955

Sebastian, Tim; Dopheide, Jörn F.; Engelberger, Rolf P.; Spirk, David; Kucher, Nils (2018). Outcomes of endovascular reconstruction of the inferior vena cava with self-expanding nitinol stents. Journal of vascular surgery. Venous and lymphatic disorders, 6(3), pp. 312-320. Elsevier 10.1016/j.jvsv.2017.11.012

Dufour, Jean-François

Miethe, Sarah; Guarino, Maria; Alhamdan, Fahd; Simon, Hans-Uwe; Renz, Harald; Dufour, Jean-François; Potaczek, Daniel P; Garn, Holger (2018). Effects of obesity on asthma: immunometabolic links. Polish archives of internal medicine, 128(7-8), pp. 469-477. Medycyna Praktyczna, Kraków, Poland 10.20452/pamw.4304

Duppenthaler, Andrea

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

Démoulins, Thomas Paul Rémi

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Döll, Frauke

Döll, Frauke; Pfeilschifter, Josef; Huwiler, Andrea (2007). Prolactin upregulates sphingosine kinase-1 expression and activity in the human breast cancer cell line MCF7 and triggers enhanced proliferation and migration. Endocrine-related cancer, 14(2), pp. 325-35. Bristol: BioScientifica Ltd. 10.1677/ERC-06-0050

Eblé, Andrée

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Echeverry, Nohemy

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Ke, Francine; Voss, Anne; Kerr, Jeffrey; O'Reilly, Lorraine; Tai, Lin; Echeverry, Nohemy; Bouillet, Philippe; Strasser, Andreas; Kaufmann, Thomas (2012). BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice. Cell death and differentiation, 19(6), pp. 915-25. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.210

Eggel, Alexander

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Engelberger, Rolf Peter

Sebastian, Tim; Dopheide, Jörn F.; Engelberger, Rolf P.; Spirk, David; Kucher, Nils (2018). Outcomes of endovascular reconstruction of the inferior vena cava with self-expanding nitinol stents. Journal of vascular surgery. Venous and lymphatic disorders, 6(3), pp. 312-320. Elsevier 10.1016/j.jvsv.2017.11.012

Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086

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Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463

Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

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Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

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Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463

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Erhardt, Martin

Theodoropoulou, Maria A; Psarra, Anastasia; Erhardt, Martin; Nikolaou, Aikaterini; Gerogiannopoulou, Anna-Dimitra D; Hadjipavlou-Litina, Dimitra; Hayashi, Daiki; Dennis, Edward A; Huwiler, Andrea; Kokotos, George (2022). N-Acylated and N-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E2. Biomolecules, 12(2) MDPI 10.3390/biom12020267

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Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041396

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Liakoni, Evangelia; Gartwyl, Fabienne; Ricklin, Meret; Exadaktylos, Aristomenis; Krähenbühl, Stephan (2018). Psychoactive substances and violent offences: A retrospective analysis of presentations to an urban emergency department in Switzerland. PLoS ONE, 13(3), e0195234. Public Library of Science 10.1371/journal.pone.0195234

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Kotelevets, Nataliya; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2012). Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. PLoS ONE, 7(6), e39209. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0039209

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Chen, Bin; Roy, Saurabh G; McMonigle, Ryan J; Keebaugh, Andrew; McCracken, Alison N; Selwan, Elizabeth; Fransson, Rebecca; Fallegger, Daniel; Huwiler, Andrea; Kleinman, Michael T; Edinger, Aimee L; Hanessian, Stephen (2016). Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo. ACS Chemical Biology, 11(2), pp. 409-414. American Chemical Society 10.1021/acschembio.5b00761

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Federzoni, Elena

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Feldmeyer, Laurence

Radonjic-Hoesli, Susanne; Brüggen, Marie-Charlotte; Feldmeyer, Laurence; Simon, Hans-Uwe; Simon, Dagmar (2021). Eosinophils in skin diseases. Seminars in immunopathology, 43(3), pp. 393-409. Springer 10.1007/s00281-021-00868-7

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Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

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Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008

Fernandez Marrero, Yuniel; Spinner, S; Jost, P J; Kaufmann, Thomas (2016). Survival control of malignant lymphocytes by anti-apoptotic MCL-1. Leukemia, 30(11), pp. 2152-2159. Nature Publishing Group 10.1038/leu.2016.213

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

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Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116

Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

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Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

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Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200

Britschgi, Adrian; Simon, Hans-Uwe; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2010). Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2. British journal of haematology, 149(1), pp. 55-64. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.08040.x

Andina, N; Conus, S; Schneider, E M; Fey, M F; Simon, H U (2009). Induction of Bim limits cytokine-mediated prolonged survival of neutrophils. Cell death and differentiation, 16(9), pp. 1248-55. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.50

Kuhn, A; Leupin, N; Fey, M.F.; Yousefi, S; Simon, H.U. (2008). Leukaemia cell lines are robust in vitro models - response to MacLeod & Drexler. British journal of haematology(142), pp. 138-141. Oxford: Wiley-Blackwell

Rizzi, Mattia; Tschan, Mario P; Britschgi, Christian; Britschgi, Adrian; Hügli, Barbara; Grob, Tobias J; Leupin, Nicolas; Mueller, Beatrice U; Simon, Hans-Uwe; Ziemiecki, Andrew; Torbett, Bruce E; Fey, Martin F; Tobler, Andreas (2007). The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Journal of leukocyte biology, 81(6), pp. 1599-608. Bethesda, Md.: Society for Leukocyte Biology 10.1189/jlb.0606400

Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692

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Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Filipenko, Iuliia

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Filipenko, Iuliia; Huwiler, Andrea (2016). The role of the S1P3 receptor in inflammation-associated proliferative disorders (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Huwiler, Andrea; Feuerherm, Astrid J; Sakem, Benjamin; Pastukhov, Oleksandr; Filipenko, Iuliia; Nguyen, Thuy; Johansen, Berit (2012). The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. British journal of pharmacology, 167(8), pp. 1691-701. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02114.x

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Petkovic, Vibor; Salemi, Souzan; Vassella, Erik; Karamitopoulou-Diamantis, Evanthia; Meinhardt, Udo J; Flück, Christa E; Mullis, Primus E (2007). Leydig-cell tumour in children: variable clinical presentation, diagnostic features, follow-up and genetic analysis of four cases. Hormone research, 67(2), pp. 89-95. Basel: Karger 10.1159/000096356

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Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706

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Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Frangež, Živa

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Freigang, Stefan Bernd

Saliakoura, Maria; Rossi, Sebastiano Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Frias Boligan, Kayluz

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Yu, Yi; Ladeiras, Diogo; Xiong, Yuyan; Frias Boligan, Kayluz; Liang, Xiujie; von Gunten, Stephan; Hunger, Robert E.; Ming, Xiu-Fen; Yang, Zhihong (2020). Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. Journal of cellular physiology, 235(12), pp. 9997-10011. Wiley 10.1002/jcp.29814

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Luetscher, Ralph N D; McKitrick, Tanya R; Gao, Chao; Mehta, Akul Y; McQuillan, Alyssa M; Kardish, Robert; Frias Boligan, Kayluz; Song, Xuezheng; Lu, Lenette; Heimburg-Molinaro, Jamie; von Gunten, Stephan; Alter, Galit; Cummings, Richard D (2020). Unique repertoire of anti-carbohydrate antibodies in individual human serum. Scientific reports, 10(1), p. 15436. Springer Nature 10.1038/s41598-020-71967-y

Boligan, Kayluz F.; Oechtering, Johanna; Keller, Christian W; Peschke, Benjamin; Rieben, Robert; Bovin, Nicolai; Kappos, Ludwig; Cummings, Richard D; Kuhle, Jens; von Gunten, Stephan; Lünemann, Jan D (2020). Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS. Neurology: Neuroimmunology and Neuroinflammation, 7(2) Wolters Kluwer Health 10.1212/NXI.0000000000000676

Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Stanczak, Michal A; Siddiqui, Shoib S; Trefny, Marcel P; Thommen, Daniela S; Frias Boligan, Kayluz; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael S; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghan; Amos, Christopher I; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E; Varki, Ajit; ... (2018). Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells. Journal of clinical investigation, 128(11), pp. 4912-4923. American Society for Clinical Investigation 10.1172/JCI120612

Frias Boligan, Kayluz; von Gunten, Stephan (2017). Innate lymphoid cells in asthma: cannabinoids on the balance. Allergy, 72(6), pp. 839-841. Wiley-Blackwell 10.1111/all.13145

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Frias Boligan, Kayluz; Mesa, Circe; Fernandez, Luis Enrique; von Gunten, Stephan (2014). Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense. Cellular and molecular life sciences, 72(7), pp. 1231-1248. Springer 10.1007/s00018-014-1799-5

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Friis, Robert

Simon, Hans-Uwe; Friis, Robert; Colombo, María I. (2017). Autophagy. In: eLS Citable reviews in the life sciences (pp. 1-10). Wiley 10.1002/9780470015902.a0021581.pub2

Simon, Hans-Uwe; Friis, Robert (2014). ATG5: a distinct role in the nucleus. Autophagy, 10(1), pp. 176-177. Landes Bioscience 10.4161/auto.26916

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Constantinou, Thecla; Baumann, Fabrizio; Lacher, Markus D; Saurer, Susanne; Friis, Robert; Dharmarajan, Arun (2008). SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation. Journal of molecular signaling, 3, p. 10. London: BioMed Central 10.1186/1750-2187-3-10

Furrer, Julien

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Fux, Michaela

Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Rohner, Lionel; Reinhart, Ramona; Hagmann, Björn; Odermatt, Andrea; Babirye, Annet; Kaufmann, Thomas; Fux, Michaela (2018). FcɛRI cross-linking and IL-3 protect human basophils from intrinsic apoptotic stress. The Journal of allergy and clinical immunology, 142(5), 1647-1650.e3. Elsevier 10.1016/j.jaci.2018.06.040

Reinhart, Ramona; Rohner, Lionel; Wicki, Simone; Fux, Michaela; Kaufmann, Thomas (2018). BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells. Cell death and differentiation, 25(1), pp. 204-216. Nature Publishing Group 10.1038/cdd.2017.154

Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, Michaela (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850

Galván Hernández, José Alberto

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Gao, Yanyun

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Geering Truffer, Barbara

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

Geering Truffer, Barbara; Schmidt-Mende, Jan; Federzoni, Elena; Stoeckle, Christina; Simon, Hans-Uwe (2011). Protein overexpression following lentiviral infection of primary mature neutrophils is due to pseudotransduction. Journal of immunological methods, 373(1-2), pp. 209-18. Amsterdam: Elsevier 10.1016/j.jim.2011.08.024

Kok, Klaartje; Geering, Barbara; Vanhaesebroeck, Bart (2009). Regulation of phosphoinositide 3-kinase expression in health and disease. Trends in biochemical sciences, 34(3), pp. 115-27. Cambridge: Elsevier Current Trends 10.1016/j.tibs.2009.01.003

Genitsch Gratwohl, Vera

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Germic, Nina

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. (In Press). Allergy Wiley 10.1111/all.15233

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

Gertsch, Jürg

Saliakoura, Maria; Reynoso-Moreno, Inés; Pozzato, Chiara; Rossi Sebastiano, Matteo; Galié, Mirco; Gertsch, Jürg; Konstantinidou, Georgia (2020). The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Oncogene, 39(14), pp. 2948-2960. Springer Nature 10.1038/s41388-020-1196-5

Gigon, Lea

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003

Girousi, Eleftheria

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Gjuroski, Ilche

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Gloor, Beat

Worni, Mathias; Güller, Ulrich; White, Rebekah R.; Castleberry, Anthony W.; Pietrobon, Ricardo; Cerny, Thomas; Gloor, Beat; Köberle, Dieter (2013). Modest Improvement in Overall Survival for Patients With Metastatic Pancreatic Cancer. Pancreas, 42(7), pp. 1157-1163. Lippincott Williams & Wilkins 10.1097/MPA.0b013e318291fbc5

Gottstein, Bruno

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Graber, Werner Adrian

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Graeter, Stefanie

Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Graeter, Stefanie Rebecca

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

Grafinger, Katharina

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Grafinger, Katharina Elisabeth; Liechti, Matthias E; Liakoni, Evangelia (2020). Clinical value of analytical testing in patients presenting with New Psychoactive Substances intoxication. British journal of clinical pharmacology, 86(3), pp. 429-436. Wiley-Blackwell 10.1111/bcp.14115

Grandgirard, Denis

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Guarino, Maria

Miethe, Sarah; Guarino, Maria; Alhamdan, Fahd; Simon, Hans-Uwe; Renz, Harald; Dufour, Jean-François; Potaczek, Daniel P; Garn, Holger (2018). Effects of obesity on asthma: immunometabolic links. Polish archives of internal medicine, 128(7-8), pp. 469-477. Medycyna Praktyczna, Kraków, Poland 10.20452/pamw.4304

Gurzeler, Ursina

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206

Güller, Ulrich

Worni, Mathias; Güller, Ulrich; White, Rebekah R.; Castleberry, Anthony W.; Pietrobon, Ricardo; Cerny, Thomas; Gloor, Beat; Köberle, Dieter (2013). Modest Improvement in Overall Survival for Patients With Metastatic Pancreatic Cancer. Pancreas, 42(7), pp. 1157-1163. Lippincott Williams & Wilkins 10.1097/MPA.0b013e318291fbc5

Haas, Nadine Agnès Marie-Anne

Bussmann, Christian; Schoepfer, Alain M; Safroneeva, Ekaterina; Haas, Nadine; Godat, Sébastien; Sempoux, Christine; Simon, Hans-Uwe; Straumann, Alex (2016). Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy, 48(12), pp. 1069-1075. Thieme 10.1055/s-0042-117274

Haas, Quentin

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Hugonnet, Marjolaine; Singh, Pushpita; Haas, Quentin; von Gunten, Stephan (2021). The Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology. Frontiers in immunology, 12, p. 799861. Frontiers Research Foundation 10.3389/fimmu.2021.799861

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Haas, Quentin; Simillion, Cedric André Marie; von Gunten, Stephan (2018). A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future? Frontiers in oncology, 8, p. 68. Frontiers Research Foundation 10.3389/fonc.2018.00068

Hafizi, Redona

Hafizi, Redona; Imeri, Faik; Wenger, Roland H.; Huwiler, Andrea (2021). S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization. International journal of molecular sciences, 22(17) MDPI 10.3390/ijms22179467

Schwalm, Stephanie; Beyer, Sandra; Hafizi, Redona; Trautmann, Sandra; Geisslinger, Gerd; Adams, David R; Pyne, Susan; Pyne, Nigel; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2021). Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis. Cellular signalling, 79(109881), p. 109881. Elsevier 10.1016/j.cellsig.2020.109881

Haimovici, Aladin

Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010

Haine, Axel

Engelberger, Rolf P.; Stuck, Anna; Spirk, David; Willenberg, Torsten; Haine, Axel; Périard, Daniel; Baumgartner, Iris; Kucher, Nils (2017). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute ilio-femoral deep vein thrombosis: one-year follow-up data of a randomized-controlled trial. Journal of thrombosis and haemostasis, 15(7), pp. 1351-1360. Wiley-Blackwell 10.1111/jth.13709

Hall, Sean

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Hammann, Felix

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Haschke, Manuel Martin

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Liakoni, Evangelia; Berger, Flavia; Klukowska-Rötzler, Jolanta; Kupferschmidt, Hugo; Haschke, Manuel; Exadaktylos, Aristomenis (2019). Characteristics of emergency department presentations requiring consultation of the national Poisons Information Centre. Swiss medical weekly, 149, w20164. EMH Media 10.4414/smw.2019.20164

Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488

Hübner, Simona T; Bertoli, Raffaela; Rätz Bravo, Alexandra E; Schaueblin, Martina; Haschke, M.; Scherer, Kathrin; Ceschi, Alessandro; Leuppi-Taegtmeyer, Anne B (2018). C-Reactive Protein and Procalcitonin in Case Reports of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. International archives of allergy and immunology, 176(1), pp. 44-54. Karger 10.1159/000487670

He, Zhaoyue

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

He, Zhaoyue; Liu, He; Moch, Holger; Simon, Hans-Uwe (2020). Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Scientific reports, 10(1), p. 720. Springer Nature 10.1038/s41598-020-57670-y

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Liu, He; He, Zhaoyue; Bode, Peter; Moch, Holger; Simon, Hans-Uwe (2018). Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Frontiers in oncology, 8(366), p. 366. Frontiers Research Foundation 10.3389/fonc.2018.00366

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2016). The Role of Autophagy in Cancer and Chemotherapy. In: Hayat, M. (ed.) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Human Diseases: Vol. 8 (pp. 253-265). Academic Press 10.1016/B978-0-12-802937-4.00014-4

He, Zhaoyue; Agostini, Massimiliano; Liu, He; Melino, Gerry; Simon, Hans-Uwe (2015). p73 regulates basal and starvation-induced liver metabolism in vivo. OncoTarget, 6(32), pp. 33178-33190. Impact Journals LLC 10.18632/oncotarget.5090

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2015). Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. Journal of molecular medicine JMM, 93(2), pp. 159-164. Springer 10.1007/s00109-014-1241-3

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2014). Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy, 10(2), pp. 372-373. Landes Bioscience 10.4161/auto.27163

He, Z.; Simon, H. U. (2013). Autophagy protects from liver injury. Cell death and differentiation, 20(7), pp. 850-851. Nature Publishing Group 10.1038/cdd.2013.43

He, Zhaoyue; Simon, Hans-Uwe (2013). A novel link between p53 and ROS. Cell Cyle, 12(2), pp. 201-202. Landes Bioscience 10.4161/cc.23418

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2013). Targeting autophagy as a potential therapeutic approach for melanoma therapy. Seminars in Cancer Biology, 5(23), pp. 352-360. Elsevier 10.1016/j.semcancer.2013.06.008

Heg, Dierik Hans

Räber, Lorenz; Ueki, Yasushi; Otsuka, Tatsuhiko; Losdat, Sylvain; Häner, Jonas D; Lonborg, Jacob; Fahrni, Gregor; Iglesias, Juan F; van Geuns, Robert-Jan; Ondracek, Anna S; Radu Juul Jensen, Maria D; Zanchin, Christian; Stortecky, Stefan; Spirk, David; Siontis, George C; Saleh, Lanja; Matter, Christian M; Daemen, Joost; Mach, François; Heg, Dik; ... (2022). Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial. JAMA - the journal of the American Medical Association, 327(18), pp. 1771-1781. American Medical Association 10.1001/jama.2022.5218

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Heidemeyer, Kristine

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Helbling, Arthur

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Heller, Manfred

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Hertig, Damian

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Heussler, Volker

Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia; ... (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. Taylor & Francis 10.1080/15548627.2020.1797280

Hlushchuk, Ruslan

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/​jimmunol.1400028

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Hofstetter, Wilhelm

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Honegger, Ulrich

De Marchis, Gian Marco; Bürgi, Sibylle; Kientsch, Urs; Honegger, Ulrich E (2006). Vitamin E reduces antidepressant-related beta-adrenoceptor down-regulation in cultured cells. Comparable effects on St. John's wort and tricyclic antidepressant treatment. Planta medica, 72(15), pp. 1436-7. Stuttgart: Thieme 10.1055/s-2006-951727

Mühlebach, S F; Karlaganis, G; Honegger, U E (2006). Kinetic assessment of persistent halogenated xenobiotics in cell culture models: comparison of mono- and poly-halogenated compounds. Chemosphere, 62(11), pp. 1838-45. Kidlington, UK: Elsevier Science 10.1016/j.chemosphere.2005.07.041

Hammon, Harald M.; Bruckmaier, Rupert M.; Honegger, Ulrich E.; Blum, Jürg W. (1994). Distribution and density of α– and β–adrenergic receptor binding sites in the bovine mammary gland. Journal of dairy research, 61(1), pp. 47-57. Cambridge University Press 10.1017/S0022029900028041

Horn, Michael

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Horn, Michael Peter

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Hosseini, Aref

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. (In Press). Allergy Wiley 10.1111/all.15233

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113

Houriet, Carine

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Houriet, C.; Simon, H.-U.; Simon, D. (2014). Hypereosinophilic Syndromes. Aktuelle Dermatologie, 40(4), pp. 127-132. Thieme 10.1055/s-0034-1365078

Hugonnet, Marjolaine Claire

Hugonnet, Marjolaine; Singh, Pushpita; Haas, Quentin; von Gunten, Stephan (2021). The Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology. Frontiers in immunology, 12, p. 799861. Frontiers Research Foundation 10.3389/fimmu.2021.799861

Humbert, Magali

Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Hunger, Robert

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Yu, Yi; Ladeiras, Diogo; Xiong, Yuyan; Frias Boligan, Kayluz; Liang, Xiujie; von Gunten, Stephan; Hunger, Robert E.; Ming, Xiu-Fen; Yang, Zhihong (2020). Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. Journal of cellular physiology, 235(12), pp. 9997-10011. Wiley 10.1002/jcp.29814

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Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

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Theodoropoulou, Maria A; Psarra, Anastasia; Erhardt, Martin; Nikolaou, Aikaterini; Gerogiannopoulou, Anna-Dimitra D; Hadjipavlou-Litina, Dimitra; Hayashi, Daiki; Dennis, Edward A; Huwiler, Andrea; Kokotos, George (2022). N-Acylated and N-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E2. Biomolecules, 12(2) MDPI 10.3390/biom12020267

Hafizi, Redona; Imeri, Faik; Wenger, Roland H.; Huwiler, Andrea (2021). S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization. International journal of molecular sciences, 22(17) MDPI 10.3390/ijms22179467

Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Imeri, Faik; Homann, Thomas; Kleuser, Burkhard; Stark, Holger; Huwiler, Andrea (2021). ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo. Molecules, 26(17) Molecular Diversity Preservation International MDPI 10.3390/molecules26175134

Huwiler, Andrea; Pfeilschifter, Josef (2021). Recuperation of Vascular Homeostasis. Circulation research, 129(2), pp. 237-239. American Heart Association 10.1161/CIRCRESAHA.121.319558

Imeri, Faik; Stepanovska Tanturovska, Bisera; Schwalm, Stephanie; Saha, Sarbari; Zeng-Brouwers, Jinyang; Pavenstädt, Herrmann; Pfeilschifter, Josef; Schaefer, Liliana; Huwiler, Andrea (2021). Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice. Matrix biology, 98, pp. 32-48. Elsevier 10.1016/j.matbio.2021.05.003

Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Schwalm, Stephanie; Beyer, Sandra; Hafizi, Redona; Trautmann, Sandra; Geisslinger, Gerd; Adams, David R; Pyne, Susan; Pyne, Nigel; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2021). Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis. Cellular signalling, 79(109881), p. 109881. Elsevier 10.1016/j.cellsig.2020.109881

Psarra, Anastasia; Theodoropoulou, Maria A; Erhardt, Martin; Mertiri, Marina; Mantzourani, Christiana; Vasilakaki, Sofia; Magrioti, Victoria; Huwiler, Andrea; Kokotos, George (2021). α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E2 (PGE2) in Rat Mesangial Cells. Biomolecules, 11(2) MDPI 10.3390/biom11020275

Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2020). Corrigendum to "Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms" [Biochim. Biophys. Acta Mol. Basis Dis. 2019 Apr 1;1865(4):774-781]. Biochimica et biophysica acta - molecular basis of disease, 1866(10), p. 165892. Elsevier 10.1016/j.bbadis.2020.165892

Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463

Stepanovska, Bisera; Huwiler, Andrea (2020). Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases. Pharmacological research, 154, p. 104170. Elsevier 10.1016/j.phrs.2019.02.009

Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041396

Stepanovska, Bisera; Lange, Antonia I; Schwalm, Stephanie; Pfeilschifter, Josef; Coldewey, Sina M; Huwiler, Andrea (2020). Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041240

Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2019). Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms. Biochimica et biophysica acta - molecular basis of disease, 1865(4), pp. 774-781. Elsevier 10.1016/j.bbadis.2018.12.022

Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992

Huwiler, Andrea; Pfeilschifter, Josef (2018). Sphingolipid signaling in renal fibrosis. Matrix biology, 68-69, pp. 230-247. Elsevier 10.1016/j.matbio.2018.01.006

Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

Huwiler, Andrea; Zangemeister-Wittke, Uwe (2018). The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: recent findings and new perspectives. Pharmacology & therapeutics, 185, pp. 34-49. Elsevier 10.1016/j.pharmthera.2017.11.001

Eresch, Jeanette; Stumpf, Martin; Koch, Alexander; Vutukuri, Rajkumar; Ferreirós, Nerea; Schreiber, Yannick; Schröder, Katrin; Devraj, Kavi; Popp, Rüdiger; Huwiler, Andrea; Hattenbach, Lars-Olof; Pfeilschifter, Josef; Pfeilschifter, Waltraud (2018). Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. Investigative ophthalmology & visual science, 59(2), pp. 653-661. Association for Research in Vision and Ophthalmology 10.1167/iovs.17-22544

Vasilakaki, Sofia; Pastukhov, Oleksandr; Mavromoustakos, Thomas; Huwiler, Andrea; Kokotos, George (2018). Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells. Molecules, 23(1) Molecular Diversity Preservation International MDPI 10.3390/molecules23010158

Beyer, Sandra; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2018). Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. Cellular physiology and biochemistry, 47(6), pp. 2522-2533. Karger 10.1159/000491625

Schwalm, Stephanie; Beyer, Sandra; Frey, Helena; Haceni, Riad; Grammatikos, Georgios; Thomas, Dominique; Geisslinger, Gerd; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2017). Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction. American journal of pathology, 187(11), pp. 2413-2429. Elsevier 10.1016/j.ajpath.2017.06.017

Hsieh, Louise Tzung-Harn; Nastase, Madalina-Viviana; Roedig, Heiko; Zeng-Brouwers, Jinyang; Poluzzi, Chiara; Schwalm, Stephanie; Fork, Christian; Tredup, Claudia; Brandes, Ralf P; Wygrecka, Malgorzata; Huwiler, Andrea; Pfeilschifter, Josef; Schaefer, Liliana (2017). Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants. International journal of molecular sciences, 18(3) Molecular Diversity Preservation International MDPI 10.3390/ijms18030595

McCracken, A N; McMonigle, R J; Tessier, J; Fransson, R; Perryman, M S; Chen, B; Keebaugh, A; Selwan, E; Barr, S A; Kim, S M; Roy, S G; Liu, G; Fallegger, D; Sernissi, L; Brandt, C; Moitessier, N; Snider, A J; Clare, S; Müschen, M; Huwiler, Andrea; ... (2017). Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation. Leukemia, 31(3), pp. 669-677. Nature Publishing Group 10.1038/leu.2016.244

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Vasilakaki, Sofia; Barbayianni, Efrosini; Magrioti, Victoria; Pastukhov, Oleksandr; Constantinou-Kokotou, Violetta; Huwiler, Andrea; Kokotos, George (2016). Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells. Bioorganic & medicinal chemistry, 24(13), pp. 3029-3034. Elsevier 10.1016/j.bmc.2016.05.017

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Chen, Bin; Roy, Saurabh G; McMonigle, Ryan J; Keebaugh, Andrew; McCracken, Alison N; Selwan, Elizabeth; Fransson, Rebecca; Fallegger, Daniel; Huwiler, Andrea; Kleinman, Michael T; Edinger, Aimee L; Hanessian, Stephen (2016). Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo. ACS Chemical Biology, 11(2), pp. 409-414. American Chemical Society 10.1021/acschembio.5b00761

Coldewey, Sina M; Benetti, Elisa; Collino, Massimo; Pfeilschifter, Josef; Sponholz, Christoph; Bauer, Michael; Huwiler, Andrea; Thiemermann, Christoph (2016). Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis. Scientific Reports, 6, p. 27594. Nature Publishing Group 10.1038/srep27594

Filipenko, Iuliia; Huwiler, Andrea (2016). The role of the S1P3 receptor in inflammation-associated proliferative disorders (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Urtz, Nicole; Gaertner, Florian; von Bruehl, Marie-Luise; Chandraratne, Sue; Rahimi, Faridun; Zhang, Lingli; Orban, Mathias; Barocke, Verena; Beil, Johannes; Schubert, Irene; Lorenz, Michael; Legate, Kyle R; Huwiler, Andrea; Pfeilschifter, Josef M; Beerli, Christian; Ledieu, David; Persohn, Elke; Billich, Andreas; Baumruker, Thomas; Mederos y Schnitzler, Michael; ... (2015). Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. Circulation research, 117(4), pp. 376-387. Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.115.306901

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Schröder, Matthias; Arlt, Olga; Schmidt, Helmut; Huwiler, Andrea; Angioni, Carlo; Pfeilschifter, Josef M; Schwiebs, Anja; Radeke, Heinfried H (2015). Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application. Biological chemistry, 396(6-7), pp. 795-802. De Gruyter 10.1515/hsz-2014-0287

Wünsche, Christin; Koch, Alexander; Goldschmeding, Roel; Schwalm, Stephanie; Meyer Zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2015). Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1851(5), pp. 519-526. Elsevier 10.1016/j.bbalip.2015.01.003

Koch, Alexander; Jäger, Manuel; Völzke, Anja; Grammatikos, Georgios; Zu Heringdorf, Dagmar Meyer; Huwiler, Andrea; Pfeilschifter, Josef (2015). Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration. Biological chemistry, 396(6-7), pp. 803-812. De Gruyter 10.1515/hsz-2014-0288

Pastukhov, Oleksandr; Schalm, Stephanie; Zangemeister-Wittke, Uwe; Fabbro, Doriano; Bornancin, Frederic; Japtok, Lukasz; Kleuser, Burkhrad; Pfeilschifter, Josef; Huwiler, Andrea (2014). The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death. British journal of pharmacology, 171(24), pp. 5829-5844. Wiley-Blackwell 10.1111/bph.12886

Imeri, Faik; Fallegger, Daniel; Zivkovic, Aleksandra; Schwalm, Stephanie; Enzmann, Gaby; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Homann, Thomas; Kleuser, Burkhard; Pfeilschifter, Josef; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2014). Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology, 85, pp. 314-327. Elsevier 10.1016/j.neuropharm.2014.05.012

Thangaiyan, Rabi; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells. Molecular carcinogenesis, 53(7), pp. 578-588. Wiley 10.1002/mc.22012

Imeri, Faik; Jashri, Ahmed; Bullazhi, Lulzime; Shabani, Agim; Mikhova, Bozhana; Dräger, Gerald; Popovski, Emil; Huwiler, Andrea (2014). Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death. Bioorganic & medicinal chemistry, 22(9), pp. 2655-2660. Elsevier 10.1016/j.bmc.2014.03.026

Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2014). Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. Basic Clinical Pharmacology and Toxicology, 1(114), pp. 44-49. Wiley 10.1111/bcpt.12103

Völzke, Anja; Koch, Alexander; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2014). Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1841(1), pp. 11-21. Elsevier 10.1016/j.bbalip.2013.09.009

Kondo, Shunya; Bottos, Alessia; Allegood, Jeremy C.; Masson, Regis; Maurer, Francisca G.; Genoud, Christel; Kaeser, Patrick; Huwiler, Andrea; Murakami, Masato; Spiegel, Sarah; Hynes, Nancy E. (2014). Memo has a novel role in S1P signaling and crucial for vascular development. PLoS ONE, 9(4), e94114. Public Library of Science 10.1371/journal.pone.0094114

Pastukhov, Oleksandr; Schalm, Stephanie; Römer, Isolde; Pfeilschifter, Josef; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts. Cellular physiology and biochemistry, 34(1), pp. 119-133. Karger 10.1159/000362989

Bhabak, Krishna P.; Kleuser, Burkhard; Huwiler, Andrea; Arenz, Christoph (2013). Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues. Bioorganic & medicinal chemistry, 21(4), pp. 874-882. Elsevier 10.1016/j.bmc.2012.12.014

Koch, Alexander; Völzke, Anja; Puff, Bianca; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2013). PARγ agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca(2+)]i increases in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(11), pp. 1634-1643. Elsevier 10.1016/j.bbalip.2013.07.011

Albinet, V.; Bats, M-L; Huwiler, Andrea; Rochaix, P.; Chevreau, C.; Ségui, B.; Levande, T.; Andrieu-Abadie, N. (2013). Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells. Oncogene, 33(26), pp. 3364-3373. Nature Publishing Group 10.1038/onc.2013.303

Schwlam, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2013). Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(1), pp. 239-250. Elsevier 10.1016/j.bbalip.2012.07.022

Koch, Alexander; Pfeilschrifter, Josef; Huwiler, Andrea (2013). Sphingosine 1-phosphate in renal diseases. Cellular physiology and biochemistry, 31(6), pp. 745-760. Karger 10.1159/000350093

Huwiler, Andrea; Feuerherm, Astrid J; Sakem, Benjamin; Pastukhov, Oleksandr; Filipenko, Iuliia; Nguyen, Thuy; Johansen, Berit (2012). The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. British journal of pharmacology, 167(8), pp. 1691-701. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02114.x

Kotelevets, Nataliya; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2012). Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. PLoS ONE, 7(6), e39209. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0039209

Koch, A; Völzke, A; Wünsche, C; Meyer zu Heringdorf, D; Huwiler, A; Pfeilschifter, J (2012). Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells. British journal of pharmacology, 166(3), pp. 1018-32. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.01824.x

Ter Braak, Michael; Claas, Ralf Frederik; Hegen, Bianca; Labocha, Sandra; Ferreirós, Nerea; Pfeilschifter, Josef; Huwiler, Andrea; van Echten-Deckert, Gerhild; Meyer Zu Heringdorf, Dagmar (2011). Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator. Biochemical pharmacology, 81(5), pp. 617-25. New York, N.Y.: Elsevier 10.1016/j.bcp.2010.12.002

Pfeilschifter, Waltraud; Czech-Zechmeister, Bo?ena; Sujak, Marian; Mirceska, Ana; Koch, Alexander; Rami, Abdelhaq; Steinmetz, Helmuth; Foerch, Christian; Huwiler, Andrea; Pfeilschifter, Josef (2011). Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia. Biochemical and biophysical research communications, 413(2), pp. 212-7. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2011.08.070

Huwiler, Andrea; Bourquin, Florence; Kotelevets, Nataliya; Pastukhov, Oleksandr; Capitani, Guido; Grütter, Markus G; Zangemeister-Wittke, Uwe (2011). A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders. PLoS ONE, 6(8), e22436. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022436

Schröder, Matthias; Richter, Cornelia; Juan, Martina Herrero San; Maltusch, Katrin; Giegold, Oliver; Quintini, Gianluca; Pfeilschifter, Josef M; Huwiler, Andrea; Radeke, Heinfried H (2011). The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen. Molecular immunology, 48(9-10), pp. 1139-48. Amsterdam: Elsevier 10.1016/j.molimm.2011.02.007

Huwiler, Andrea; Kotelevets, Nataliya; Xin, Cuiyan; Pastukhov, Oleksandr; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe (2011). Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage. British journal of pharmacology, 162(2), pp. 532-43. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.01053.x

Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2010). Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation. British journal of pharmacology, 160(7), pp. 1641-51. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.00818.x

Puneet, Padmam; Yap, Celestial T; Wong, Lingkai; Lam, Yulin; Koh, Dow Rhoon; Moochhala, Shabbir; Pfeilschifter, Josef; Huwiler, Andrea; Melendez, Alirio J (2010). SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis. Science, 328(5983), pp. 1290-4. Washington, D.C.: American Association for the Advancement of Science 10.1126/science.1188635

Ren, Shuyu; Xin, Cuiyan; Pfeilschifter, Josef; Huwiler, Andrea (2010). A novel mode of action of the putative sphingosine kinase inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole (SKI II): induction of lysosomal sphingosine kinase 1 degradation. Cellular physiology and biochemistry, 26(1), pp. 97-104. Basel: Karger 10.1159/000315110

Förster, Ankathrin; Emmler, Tanja; Schwalm, Stephanie; Ebadi, Mahsa; Heringdorf, Dagmar Meyer Zu; Nieuwenhuis, Barbara; Kleuser, Burkhardt; Huwiler, Andrea; Pfeilschifter, Josef (2010). Glucocorticoids protect renal mesangial cells from apoptosis by increasing cellular sphingosine-1-phosphate. Kidney international, 77(10), pp. 870-9. New York, N.Y.: Nature Publishing Group 10.1038/ki.2010.62

Czech, Bozena; Pfeilschifter, Waltraud; Mazaheri-Omrani, Niloufar; Strobel, Marc André; Kahles, Timo; Neumann-Haefelin, Tobias; Rami, Abdelhaq; Huwiler, Andrea; Pfeilschifter, Josef (2009). The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. Biochemical and biophysical research communications, 389(2), pp. 251-6. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2009.08.142

Ren, Shuyu; Babelova, Andrea; Moreth, Kristin; Xin, Cuiyan; Eberhardt, Wolfgang; Doller, Anke; Pavenstädt, Hermann; Schaefer, Liliana; Pfeilschifter, Josef; Huwiler, Andrea (2009). Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. Kidney international, 76(8), pp. 857-67. New York, N.Y.: Nature Publishing Group 10.1038/ki.2009.297

Huwiler, Andrea; Pfeilschifter, Josef (2009). Lipids as targets for novel anti-inflammatory therapies. Pharmacology & therapeutics, 124(1), pp. 96-112. Amsterdam: Elsevier 10.1016/j.pharmthera.2009.06.008

Pushparaj, Peter N; Manikandan, Jayapal; Tay, Hwee Kee; H'ng, Shiau Chen; Kumar, Srinivasan D; Pfeilschifter, Josef; Huwiler, Andrea; Melendez, Alirio J (2009). Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo. Journal of immunology, 183(1), pp. 221-7. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803430

Nieuwenhuis, Barbara; Lüth, Anja; Chun, Jerold; Huwiler, Andrea; Pfeilschifter, Josef; Schäfer-Korting, Monika; Kleuser, Burkhard (2009). Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P(3) in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone. International journal of molecular medicine, 87(6), pp. 645-57. Athens: Spandidos Publications 10.1007/s00109-009-0468-x

Huwiler, A; Pfeilschifter, J (2009). Lipid signalling - Ample opportunitites for novel drug targets. BioForum Europe, 10/200, pp. 22-23. Darmstadt: GIT-Verlag

Hofmann, Lotte P; Ren, Shuyu; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2008). Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner. Biological chemistry, 389(11), pp. 1399-407. Berlin: Walter de Gruyter 10.1515/BC.2008.160

Huwiler, Andrea; Pfeilschifter, Josef (2008). New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets. Biochemical pharmacology, 75(10), pp. 1893-900. New York, N.Y.: Elsevier 10.1016/j.bcp.2007.12.018

Schwalm, Stephanie; Döll, Frauke; Römer, Isolde; Bubnova, Svetlana; Pfeilschifter, Josef; Huwiler, Andrea (2008). Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells. Biochemical and biophysical research communications, 368(4), pp. 1020-5. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2008.01.132

Schade-Kampmann, G; Huwiler, A; Hebeisen, M; Hessler, T; Di Berardino, M (2008). On-chip non-invasive and label-free cell discrimination by impedance spectroscopy. Anaesthesia, 41(5), pp. 830-40. Oxford: Wiley-Blackwell 10.1111/j.1365-2184.2008.00548.x

Doller, Anke; Akool, El-Sayed; Huwiler, Andrea; Müller, Roswitha; Radeke, Heinfried H; Pfeilschifter, Josef; Eberhardt, Wolfgang (2008). Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA. Molecular and cellular biology, 28(8), pp. 2608-25. Washington, D.C.: American Society for Microbiology 10.1128/MCB.01530-07

Huwiler, Andrea (2008). Antiarthrotic and Immunomodulatory Activity (Check index of the book for specific contributions). In: Vogel, Hans Gerhard (ed.) Drug Discovery and Evaluation: Pharmacological Assays, Vol 1 and 2 (pp. 1117-1190). Heidelberg: Springer Verlag 10.1007/978-3-540-70995-4_10

Klawitter, S; Hofmann, L P; Pfeilschifter, J; Huwiler, A (2007). Extracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase-1 expression and activity. British journal of pharmacology, 150(3), pp. 271-80. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0706983

Huwiler, Andrea; Zangemeister-Wittke, Uwe (2007). Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. Critical reviews in oncology, hematology, 63(2), pp. 150-9. Boca Raton, Fla.: Elsevier 10.1016/j.critrevonc.2007.04.010

Döll, Frauke; Pfeilschifter, Josef; Huwiler, Andrea (2007). Prolactin upregulates sphingosine kinase-1 expression and activity in the human breast cancer cell line MCF7 and triggers enhanced proliferation and migration. Endocrine-related cancer, 14(2), pp. 325-35. Bristol: BioScientifica Ltd. 10.1677/ERC-06-0050

Xin, Cuiyan; Ren, Shuyu; Eberhardt, Wolfgang; Pfeilschifter, Josef; Huwiler, Andrea (2007). Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1beta-induced prostaglandin E2 formation. Journal of lipid research, 48(9), pp. 1985-96. Bethesda, Md.: American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M700077-JLR200

Ulrich, Sandra; Huwiler, Andrea; Loitsch, Stefan; Schmidt, Helmut; Stein, Jürgen M (2007). De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity. Biochemical pharmacology, 74(2), pp. 281-9. New York, N.Y.: Elsevier 10.1016/j.bcp.2007.04.001

Doller, Anke; Huwiler, Andrea; Müller, Roswitha; Radeke, Heinfried H; Pfeilschifter, Josef; Eberhardt, Wolfgang (2007). Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Molecular biology of the cell, 18(6), pp. 2137-48. Bethesda, Md.: American Society for Cell Biology 10.1091/mbc.E06-09-0850

Xin, C; Ren, S; Eberhardt, W; Pfeilschifter, J; Huwiler, A (2007). FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism. British journal of pharmacology, 150(7), pp. 943-50. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0707171

Zangemeister-Wittke, Uwe; Huwiler, Andrea (2006). Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer. Cancer biology & therapy, 5(10), pp. 1355-1356. Georgetown, Tex.: Landes Bioscience 10.4161/cbt.5.10.3488

Huwiler, Andrea; Pfeilschifter, Josef (2006). Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy. Current pharmaceutical design, 12(35), pp. 4625-35. Hilversum: Bentham Science Publishers 10.2174/138161206779010422

Huwiler, Andrea; Pfeilschifter, Josef (2006). Hypoxia and lipid signaling. Biological chemistry, 387(10-11), pp. 1321-8. Berlin: Walter de Gruyter 10.1515/BC.2006.165

Huwiler, Andrea; Döll, Frauke; Ren, Shuyu; Klawitter, Sabine; Greening, Anna; Römer, Isolde; Bubnova, Svetlana; Reinsberg, Luise; Pfeilschifter, Josef (2006). Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism. Biochimica and biophysica acta - molecular and cell biology of lipids, 1761(3), pp. 367-376. Biochimica and biophysica acta - molecular and cell biology of lipids: Elsevier 10.1016/j.bbalip.2006.02.007

Xin, Cuiyan; Ren, Shuyu; Eberhardt, Wolfgang; Pfeilschifter, Josef; Huwiler, Andrea (2006). The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells. British journal of pharmacology, 147(2), pp. 164-74. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0706452

Plesková, Miriam; Beck, Karl-Friedrich; Behrens, Meik Helmut; Huwiler, Andrea; Fichtlscherer, Birgit; Wingerter, Oliver; Brandes, Ralf P; Mülsch, Alexander; Pfeilschifter, Josef (2006). Nitric oxide down-regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cells. FASEB journal, 20(1), pp. 139-41. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.05-3791fje

Häner, Jonas

Räber, Lorenz; Ueki, Yasushi; Otsuka, Tatsuhiko; Losdat, Sylvain; Häner, Jonas D; Lonborg, Jacob; Fahrni, Gregor; Iglesias, Juan F; van Geuns, Robert-Jan; Ondracek, Anna S; Radu Juul Jensen, Maria D; Zanchin, Christian; Stortecky, Stefan; Spirk, David; Siontis, George C; Saleh, Lanja; Matter, Christian M; Daemen, Joost; Mach, François; Heg, Dik; ... (2022). Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial. JAMA - the journal of the American Medical Association, 327(18), pp. 1771-1781. American Medical Association 10.1001/jama.2022.5218

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Zanchin, Christian; Ueki, Yasushi; Losdat, Sylvain; Fahrni, Gregor; Daemen, Joost; Ondracek, Anna S; Häner, Jonas D.; Stortecky, Stefan; Otsuka, Tatsuhiko; Siontis, George C.M.; Rigamonti, Fabio; Radu, Maria; Spirk, David; Kaiser, Christoph; Engstrom, Thomas; Lang, Irene; Koskinas, Konstantinos C.; Räber, Lorenz (2021). In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study. European heart journal - cardiovascular imaging, 22(7), pp. 824-834. Oxford University Press 10.1093/ehjci/jez318

Imeri, Faik

Hafizi, Redona; Imeri, Faik; Wenger, Roland H.; Huwiler, Andrea (2021). S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization. International journal of molecular sciences, 22(17) MDPI 10.3390/ijms22179467

Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Imeri, Faik; Homann, Thomas; Kleuser, Burkhard; Stark, Holger; Huwiler, Andrea (2021). ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo. Molecules, 26(17) Molecular Diversity Preservation International MDPI 10.3390/molecules26175134

Imeri, Faik; Stepanovska Tanturovska, Bisera; Schwalm, Stephanie; Saha, Sarbari; Zeng-Brouwers, Jinyang; Pavenstädt, Herrmann; Pfeilschifter, Josef; Schaefer, Liliana; Huwiler, Andrea (2021). Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice. Matrix biology, 98, pp. 32-48. Elsevier 10.1016/j.matbio.2021.05.003

Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Imeri, Faik; Fallegger, Daniel; Zivkovic, Aleksandra; Schwalm, Stephanie; Enzmann, Gaby; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Homann, Thomas; Kleuser, Burkhard; Pfeilschifter, Josef; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2014). Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology, 85, pp. 314-327. Elsevier 10.1016/j.neuropharm.2014.05.012

Imeri, Faik; Jashri, Ahmed; Bullazhi, Lulzime; Shabani, Agim; Mikhova, Bozhana; Dräger, Gerald; Popovski, Emil; Huwiler, Andrea (2014). Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death. Bioorganic & medicinal chemistry, 22(9), pp. 2655-2660. Elsevier 10.1016/j.bmc.2014.03.026

Inderkum, Andrea

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Iype, Joseena Mariam

Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x

Jafari, Morteza

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Jakob, Stephan

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

von Gunten, Stephan; Jakob, Stephan M; Geering, Barbara; Takala, Jukka; Simon, Hans-Uwe (2009). Different patterns of Siglec-9-mediated neutrophil death responses in septic shock. Shock, 32(4), pp. 386-92. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181a1bc98

Jandus, Camilla

Démoulins, Thomas; Bassi, Isabelle; Thomann-Harwood, Lisa; Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan; Mc Cullogh, Kenneth C (2013). Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells. Nanomedicine-Nanotechnology Biology and Medicine, 9(6), pp. 806-817. Elsevier 10.1016/j.nano.2013.01.002

Braun, Marion; Jandus, Camilla; Maurer, Patrik; Hammann-Haenni, Anya; Schwarz, Katrin; Bachmann, Martin F; Speiser, Daniel E; Romero, Pedro (2012). Virus-like particles induce robust human T-helper cell responses. European journal of immunology, 42(2), pp. 330-40. Weinheim: Wiley-VCH 10.1002/eji.201142064

Baumgaertner, Petra; Jandus, Camilla; Rivals, Jean-Paul; Derré, Laurent; Lövgren, Tanja; Baitsch, Lukas; Guillaume, Philippe; Luescher, Immanuel F; Berthod, Gregoire; Matter, Maurice; Rufer, Nathalie; Michielin, Olivier; Speiser, Daniel E (2012). Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells. International journal of cancer, 130(11), pp. 2607-17. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.26297

Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan (2011). Targeting siglecs--a novel pharmacological strategy for immuno- and glycotherapy. Biochemical pharmacology, 82(4), pp. 323-32. New York, N.Y.: Elsevier 10.1016/j.bcp.2011.05.018

Derré, Laurent; Jandus, Camilla; Baumgaertner, Petra; Posevitz, Vilmos; Devêvre, Estelle; Romero, Pedro; Speiser, Daniel E (2010). Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses. Methods in molecular biology, 626, pp. 231-249. Totowa, N.J.: Humana Press 10.1007/978-1-60761-585-9_16

Derré, Laurent; Rivals, Jean-Paul; Jandus, Camilla; Pastor, Sonia; Rimoldi, Donata; Romero, Pedro; Michielin, Olivier; Olive, Daniel; Speiser, Daniel E (2010). BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of clinical investigation, 120(1), pp. 157-67. Ann Arbor, Mich.: American Society for Clinical Investigation 10.1172/JCI40070

Jenni, Aurelio Leandro

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Juillerat, Pascal

Schoepfer, Alain M; Henchoz, Sarah; Biedermann, Luc; Schreiner, Philipp; Greuter, Thomas; Reinhard, Antoine; Senn, Jonduri; Franke, Annett; Burri, Emanuel; Juillerat, Pascal; Simon, Hans-Uwe; Straumann, Alex; Safroneeva, Ekaterina; Godat, Sébastien (2021). Technical feasibility, clinical effectiveness, and safety of esophageal stricture dilation using a novel endoscopic attachment cap in adults with eosinophilic esophagitis. Gastrointestinal endoscopy, 94(5), 912-919.e2. Elsevier 10.1016/j.gie.2021.05.017

Jörg, Lukas

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Karamitopoulou, Evanthia

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Kassahn, Daniela

Kassahn, D; Nachbur, U; Conus, S; Micheau, O; Schneider, P; Simon, H-U; Brunner, T (2009). Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell death and differentiation, 16(1), pp. 115-24. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.133

Katsaros, Christos

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Kouskoura, Thaleia; Katsaros, Christos; von Gunten, Stephan (2017). The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM). Frontiers in physiology, 8(67), p. 67. Frontiers Research Foundation 10.3389/fphys.2017.00067

Kaufmann, Thomas

Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Meinhardt, Anna-Lena; Munkhbaatar, Enkhtsetseg; Höckendorf, Ulrike; Dietzen, Michelle; Dechant, Marta; Anton, Martina; Jacob, Anne; Steiger, Katja; Weichert, Wilko; Brcic, Luka; McGranahan, Nicholas; Branca, Caterina; Kaufmann, Thomas; Dengler, Michael A; Jost, Philipp J (2022). The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner. Oncogene, 41(9), pp. 1376-1382. Springer Nature 10.1038/s41388-021-02161-1

Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

Burgener, Sabrina Sofia; Brügger, Melanie; Leborgne, Nathan Georges François; Sollberger, Sophia; Basilico, Paola; Kaufmann, Thomas; Bird, Phillip Ian; Benarafa, Charaf (2021). Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. Frontiers in cell and developmental biology, 9, p. 630166. Frontiers 10.3389/fcell.2021.630166

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Naim, Samara; Kaufmann, Thomas (2020). The Multifaceted Roles of the BCLL-2 Family Member BOK. Frontiers in cell and developmental biology, 8 Frontiers 10.3389/fcell.2020.574338

Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Owsley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2020). Correction: TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell death & disease, 11(1), p. 56. Springer Nature 10.1038/s41419-020-2261-2

Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x

Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Crowley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2019). TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell death & disease, 10(10), p. 700. Nature Publishing Group 10.1038/s41419-019-1938-x

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116

Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005

Rohner, Lionel; Reinhart, Ramona; Hagmann, Björn; Odermatt, Andrea; Babirye, Annet; Kaufmann, Thomas; Fux, Michaela (2018). FcɛRI cross-linking and IL-3 protect human basophils from intrinsic apoptotic stress. The Journal of allergy and clinical immunology, 142(5), 1647-1650.e3. Elsevier 10.1016/j.jaci.2018.06.040

Reinhart, Ramona; Kaufmann, Thomas (2018). IL-4 enhances survival of in vitro-differentiated mouse basophils through transcription-independent signaling downstream of PI3K. Cell death & disease, 9(7), p. 713. Nature Publishing Group 10.1038/s41419-018-0754-z

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V; Arama, Eli; Baehrecke, Eric H; Barlev, Nickolai A; Bazan, Nicolas G; Bernassola, Francesca; Bertrand, Mathieu J M; Bianchi, Katiuscia; Blagosklonny, Mikhail V; ... (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell death and differentiation, 25(3), pp. 486-541. Nature Publishing Group 10.1038/s41418-017-0012-4

Wicki, Simone; Gurzeler, Ursina; Corazza, Nadia; Genitsch, Vera; Wong, Wendy Wei-Lynn; Kaufmann, Thomas (2018). Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss. International journal of molecular sciences, 19(3) Molecular Diversity Preservation International MDPI 10.3390/ijms19030684

Reinhart, Ramona; Rohner, Lionel; Wicki, Simone; Fux, Michaela; Kaufmann, Thomas (2018). BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells. Cell death and differentiation, 25(1), pp. 204-216. Nature Publishing Group 10.1038/cdd.2017.154

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40

Sharma, Sachin; Kaufmann, Thomas; Biswas, Subhrajit (2017). Impact of inhibitor of apoptosis proteins on immune modulation and inflammation. Immunology and cell biology, 95(3), pp. 236-243. Nature Publishing Group 10.1038/icb.2016.101

Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008

Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, Michaela (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850

Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311

Tuzlak, Selma; Kaufmann, Thomas; Villunger, Andreas (2016). Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis. Genes & development, 30(19), pp. 2133-2151. Cold Spring Harbor Laboratory Press 10.1101/gad.289298.116

Fernandez Marrero, Yuniel; Spinner, S; Jost, P J; Kaufmann, Thomas (2016). Survival control of malignant lymphocytes by anti-apoptotic MCL-1. Leukemia, 30(11), pp. 2152-2159. Nature Publishing Group 10.1038/leu.2016.213

D'Orsi, Beatrice; Engel, Tobias; Pfeiffer, Shona; Nandi, Saheli; Kaufmann, Thomas; Henshall, David C; Prehn, Jochen H M (2016). Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. Journal of neuroscience, 36(16), pp. 4564-4578. Society for Neuroscience 10.1523/JNEUROSCI.3780-15.2016

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Reinhart, Ramona; Wicki, Simone; Kaufmann, Thomas (2016). In Vitro Differentiation of Mouse Granulocytes. Methods in molecular biology, 1419, pp. 95-107. Humana Press 10.1007/978-1-4939-3581-9_8

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Targeting disease by immunomodulation. Cell death and differentiation, 22(2), pp. 185-186. Nature Publishing Group 10.1038/cdd.2014.166

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137

Kaufmann, Thomas; Reinhart, Ramona; Wicki, Simone (2015). In vitro differentiation of mouse granulocytes. Programmed Cell Death: Methods and Protocols (In Press). In: Puthalakath, Hamsa; Hawkins, Christine (eds.) Programmed Cell Death: Methods and Protocols. Methods in Molecular Biology. Humana Press

Andree, Maria; Seeger, Jens M.; Schüll, Stephan; Coutelle, Oliver; Wagner-Stippich, Diana; Wiegmann, Katja; Wunderlich, Claudia M.; Birkmann, Kerstin; Broxtermann, Pia; Witt, Axel; Fritsch, Melanie; Martinelli, Paola; Bielig, Harald; Lamkemeyer, Tobias; Rugarli, Elena I.; Kaufmann, Thomas; Sterner-Kock, Anja; Wunderlich, F. Thomas; Villunger, Andreas; Martins, L. Miguel; ... (2014). BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO journal, 33(19), pp. 2171-2187. Nature Publishing Group 10.15252/embj.201387244

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Yabal, Monica; Müller, Nicole; Adler, Heiko; Knies, Nathalie; Gross, Christina J.; Damgaard, Rune Busk; Kanegane, Hirokazu; Ringelhan, Marc; Kaufmann, Thomas; Heikenwächter, Mathias; Strasser, Andreas; Gross, Olaf; Ruland, Jürgen; Peschel, Christian; Gyrd-Hansen, Mads; Jost, Philipp J. (2014). XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation. Cell reports, 7(6), pp. 1795-1808. Cell Press 10.1016/j.celrep.2014.05.008

Herold, Marco J.; Rohrbeck, Leona; Lang, Mathias J.; Grumont, Raelene; Gerondakis, Steve; Tai, Lin; Bouillet, Philippe; Kaufmann, Thomas; Strasser, Andreas (2013). Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein. EMBO REPORTS, 14(11), pp. 992-998. Nature 10.1038/embor.2013.152

Schulman, Jacqualyn J; Wright, Fiorrest A; Kaufmann, Thomas; Wojcikiewicz, Richard J H (2013). The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage. Journal of biological chemistry, 288(35), pp. 25340-25349. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.496570

Ke, Francine; Kaufmann, Thomas; Bouillet, Philippe; Strasser, Andreas; Kerr, Jeffrey; Voss, Anne K (2013). Consequences of the combined loss of BOK and BAK or BOK and BAX. Cell death & disease, 4(6), e650. Nature Publishing Group 10.1038/cddis.2013.176

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Kaufmann, Thomas; Strasser, Andreas; Jost, Philipp J (2012). Fas death receptor signalling: roles of Bid and XIAP. Cell death and differentiation, 19(1), pp. 42-50. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.121

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3, e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Corazza, Nadia; Kaufmann, Thomas (2012). Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models. Allergy, 67(12), pp. 1483-90. Oxford: Wiley-Blackwell 10.1111/all.12065

Damgaard, Rune Busk; Nachbur, Ueli; Yabal, Monica; Wong, Wendy Wei-Lynn; Fiil, Berthe Katrine; Kastirr, Mischa; Rieser, Eva; Rickard, James Arthur; Bankovacki, Aleksandra; Peschel, Christian; Ruland, Juergen; Bekker-Jensen, Simon; Mailand, Niels; Kaufmann, Thomas; Strasser, Andreas; Walczak, Henning; Silke, John; Jost, Philipp J; Gyrd-Hansen, Mads (2012). The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Molecular cell, 46(6), pp. 746-58. Cambridge, Mass.: Cell Press 10.1016/j.molce1.2012.04.014

Ke, Francine; Voss, Anne; Kerr, Jeffrey; O'Reilly, Lorraine; Tai, Lin; Echeverry, Nohemy; Bouillet, Philippe; Strasser, Andreas; Kaufmann, Thomas (2012). BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice. Cell death and differentiation, 19(6), pp. 915-25. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.210

von Gunten, Stephan; Kaufmann, Thomas (2012). Glucocorticoids 'on air'. Allergy, 67(2), pp. 144-6. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02778.x

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2, e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206

Jost, Philipp J; Kaufmann, Thomas (2010). Cancer caused by too much apoptosis--an intriguing contradiction? Hepatology, 51(4), pp. 1110-1112. Hoboken, N.J.: Wiley Interscience 10.1002/hep.23314

Jost, Philipp J; Grabow, Stephanie; Gray, Daniel; McKenzie, Mark D; Nachbur, Ueli; Huang, David C S; Bouillet, Philippe; Thomas, Helen E; Borner, Christoph; Silke, John; Strasser, Andreas; Kaufmann, Thomas (2009). XIAP discriminates between type I and type II FAS-induced apoptosis. Nature, 460(7258), pp. 1035-1039. London: Macmillan Journals Ltd. 10.1038/nature08229

Bianchi, K; Jost, P J; Kaufmann, T; Rutkowski, R (2009). International EMBO Workshop on 'Model Organisms in Cell Death Research', Obergurgl (Austria). Cell death and differentiation, 16(8), pp. 1180-3. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.60

O'Reilly, Lorraine A; Kruse, Elizabeth A; Puthalakath, Hamsa; Kelly, Priscilla N; Kaufmann, Thomas; Huang, David C S; Strasser, Andreas (2009). MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation. Journal of immunology, 183(1), pp. 261-9. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803853

Kaufmann, Thomas; Jost, Philipp J; Pellegrini, Marc; Puthalakath, Hamsa; Gugasyan, Raffi; Gerondakis, Steve; Cretney, Erika; Smyth, Mark J; Silke, John; Hakem, Razq; Bouillet, Philippe; Mak, Tak W; Dixit, Vishva M; Strasser, Andreas (2009). Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. Immunity, 30(1), pp. 56-66. Cambridge, Mass.: Cell Press 10.1016/j.immuni.2008.10.017

Jabbour, A M; Heraud, J E; Daunt, C P; Kaufmann, T; Sandow, J; O'Reilly, L A; Callus, B A; Lopez, A; Strasser, A; Vaux, D L; Ekert, P G (2009). Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation, 16(4), pp. 555-63. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.179

Walter, Dorothée; Schmich, Kathrin; Vogel, Sandra; Pick, Robert; Kaufmann, Thomas; Hochmuth, Florian Christoph; Haber, Angelika; Neubert, Karin; McNelly, Sabine; von Weizsäcker, Fritz; Merfort, Irmgard; Maurer, Ulrich; Strasser, Andreas; Borner, Christoph (2008). Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Hepatology, 48(6), pp. 1942-53. Hoboken, N.J.: Wiley Interscience 10.1002/hep.22541

McKenzie, Mark D; Carrington, Emma M; Kaufmann, Thomas; Strasser, Andreas; Huang, David C S; Kay, Thomas W H; Allison, Janette; Thomas, Helen E (2008). Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells. Diabetes, 57(5), pp. 1284-92. Alexandria, Va.: American Diabetes Association 10.2337/db07-1692

Keogh, Adrian

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3, e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Keogh-Stroka, Deborah M.

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Ketkar, Avanee

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Kim-Fuchs, Corina

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Klapan, Kim

Klapan, Kim; Simon, Dagmar; Karaulov, Alexander; Gomzikova, Marina; Rizvanov, Albert; Yousefi, Shida; Simon, Hans-Uwe (2022). Autophagy and Skin Diseases. Frontiers in Pharmacology, 13, p. 844756. Frontiers 10.3389/fphar.2022.844756

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Klukowska-Rötzler, Jolanta

Liakoni, Evangelia; Berger, Flavia; Klukowska-Rötzler, Jolanta; Kupferschmidt, Hugo; Haschke, Manuel; Exadaktylos, Aristomenis (2019). Characteristics of emergency department presentations requiring consultation of the national Poisons Information Centre. Swiss medical weekly, 149, w20164. EMH Media 10.4414/smw.2019.20164

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Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Grafinger, Katharina Elisabeth; Liechti, Matthias E; Liakoni, Evangelia (2020). Clinical value of analytical testing in patients presenting with New Psychoactive Substances intoxication. British journal of clinical pharmacology, 86(3), pp. 429-436. Wiley-Blackwell 10.1111/bcp.14115

Liakoni, Evangelia; Berger, Flavia; Klukowska-Rötzler, Jolanta; Kupferschmidt, Hugo; Haschke, Manuel; Exadaktylos, Aristomenis (2019). Characteristics of emergency department presentations requiring consultation of the national Poisons Information Centre. Swiss medical weekly, 149, w20164. EMH Media 10.4414/smw.2019.20164

Keller, Sarah A; Klukowska-Rötzler, Jolanta; Schenk-Jaeger, Katharina M; Kupferschmidt, Hugo; Exadaktylos, Aristomenis; Lehmann, Beat; Liakoni, Evangelia (2018). Mushroom Poisoning-A 17 Year Retrospective Study at a Level I University Emergency Department in Switzerland. International journal of environmental research and public health, 15(12) Molecular Diversity Preservation International MDPI 10.3390/ijerph15122855

Liakoni, Evangelia; Gartwyl, Fabienne; Ricklin, Meret; Exadaktylos, Aristomenis; Krähenbühl, Stephan (2018). Psychoactive substances and violent offences: A retrospective analysis of presentations to an urban emergency department in Switzerland. PLoS ONE, 13(3), e0195234. Public Library of Science 10.1371/journal.pone.0195234

Maier, Larissa J; Liakoni, Evangelia; Schildmann, Jan; Schaub, Michael P; Liechti, Matthias E (2015). Swiss University Students' Attitudes toward Pharmacological Cognitive Enhancement. PLoS ONE, 10(12), e0144402. Public Library of Science 10.1371/journal.pone.0144402

Liakoni, Evangelia; Schaub, Michael P; Maier, Larissa J; Glauser, Gaëlle-Vanessa; Liechti, Matthias E (2015). The Use of Prescription Drugs, Recreational Drugs, and "Soft Enhancers" for Cognitive Enhancement among Swiss Secondary School Students. PLoS ONE, 10(10), e0141289. Public Library of Science 10.1371/journal.pone.0141289

Liu, He

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Müller, Ines; Strozyk, Elwira; Schindler, Sebastian; Beissert, Stefan; Oo, Htoo Zarni; Sauter, Thomas; Lucarelli, Philippe; Raeth, Sebastian; Hausser, Angelika; Al Nakouzi, Nader; Fazli, Ladan; Gleave, Martin E; Liu, He; Simon, Hans-Uwe; Walczak, Henning; Green, Douglas R; Bartek, Jiri; Daugaard, Mads; Kulms, Dagmar (2020). Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. Molecular cell, 77(5), 970-984.e7. Cell Press 10.1016/j.molcel.2019.12.023

He, Zhaoyue; Liu, He; Moch, Holger; Simon, Hans-Uwe (2020). Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Scientific reports, 10(1), p. 720. Springer Nature 10.1038/s41598-020-57670-y

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Liu, He; He, Zhaoyue; Bode, Peter; Moch, Holger; Simon, Hans-Uwe (2018). Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Frontiers in oncology, 8(366), p. 366. Frontiers Research Foundation 10.3389/fonc.2018.00366

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Dhayade, Sandeep; Kaesler, Susanne; Sinnberg, Tobias; Dobrowinski, Hyazinth; Peters, Stefanie; Naumann, Ulrike; Liu, He; Hunger, Robert E.; Thunemann, Martin; Biedermann, Tilo; Schittek, Birgit; Simon, Hans-Uwe; Feil, Susanne; Feil, Robert (2016). Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth. Cell reports, 14(11), pp. 2599-2610. Cell Press 10.1016/j.celrep.2016.02.028

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2016). The Role of Autophagy in Cancer and Chemotherapy. In: Hayat, M. (ed.) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Human Diseases: Vol. 8 (pp. 253-265). Academic Press 10.1016/B978-0-12-802937-4.00014-4

He, Zhaoyue; Agostini, Massimiliano; Liu, He; Melino, Gerry; Simon, Hans-Uwe (2015). p73 regulates basal and starvation-induced liver metabolism in vivo. OncoTarget, 6(32), pp. 33178-33190. Impact Journals LLC 10.18632/oncotarget.5090

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2015). Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. Journal of molecular medicine JMM, 93(2), pp. 159-164. Springer 10.1007/s00109-014-1241-3

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2014). Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy, 10(2), pp. 372-373. Landes Bioscience 10.4161/auto.27163

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2013). Targeting autophagy as a potential therapeutic approach for melanoma therapy. Seminars in Cancer Biology, 5(23), pp. 352-360. Elsevier 10.1016/j.semcancer.2013.06.008

Lochmatter, Didier

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Loforese, Giulio

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Losdat, Sylvain Pierre

Räber, Lorenz; Ueki, Yasushi; Otsuka, Tatsuhiko; Losdat, Sylvain; Häner, Jonas D; Lonborg, Jacob; Fahrni, Gregor; Iglesias, Juan F; van Geuns, Robert-Jan; Ondracek, Anna S; Radu Juul Jensen, Maria D; Zanchin, Christian; Stortecky, Stefan; Spirk, David; Siontis, George C; Saleh, Lanja; Matter, Christian M; Daemen, Joost; Mach, François; Heg, Dik; ... (2022). Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial. JAMA - the journal of the American Medical Association, 327(18), pp. 1771-1781. American Medical Association 10.1001/jama.2022.5218

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Zanchin, Christian; Ueki, Yasushi; Losdat, Sylvain; Fahrni, Gregor; Daemen, Joost; Ondracek, Anna S; Häner, Jonas D.; Stortecky, Stefan; Otsuka, Tatsuhiko; Siontis, George C.M.; Rigamonti, Fabio; Radu, Maria; Spirk, David; Kaiser, Christoph; Engstrom, Thomas; Lang, Irene; Koskinas, Konstantinos C.; Räber, Lorenz (2021). In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study. European heart journal - cardiovascular imaging, 22(7), pp. 824-834. Oxford University Press 10.1093/ehjci/jez318

Lyck, Ruth

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Macpherson, Andrew

Rollenske, Tim; Burkhalter, Sophie; Muerner, Lukas; von Gunten, Stephan; Lukasiewicz, Jolanta; Wardemann, Hedda; Macpherson, Andrew J. (2021). Parallelism of intestinal secretory IgA shapes functional microbial fitness. Nature, 598(7882), pp. 657-661. Springer Nature 10.1038/s41586-021-03973-7

Maire, Renaud Sylvain

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Mandel, Therese

Reinhardt, Didier; Pesce, Eva-Rachele; Stieger, Pia; Mandel, Therese; Baltensperger, Kurt; Bennett, Malcolm; Traas, Jan; Friml, Jiří; Kuhlemeier, Cris (2003). Regulation of phyllotaxis by polar auxin transport. Nature, 426(6964), pp. 255-260. Macmillan Journals Ltd. 10.1038/nature02081

Maneva Timcheva, Tankica

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Marinoni, Ilaria

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Markov, Nikita

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Markov, Nikita; Simon, Hans-Uwe (2020). IL-37: A new player in the chronic rhinosinusitis arena. The Journal of allergy and clinical immunology, 145(1), pp. 105-107. Elsevier 10.1016/j.jaci.2019.10.018

Marti, Thomas

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Maskey, Dipak

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Meneses Moreno, Niurka

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Merz, Christina

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Stoeckle, Christina; Rota, Ioanna A.; Tolosa, Eva; Haller, Christoph; Melms, Arthur; Adamopoulou, Eleni (2013). Isolation of myeloid dendritic cells and epithelial cells from human thymus. Journal of visualized experiments, 79(79), e50951. MYJoVE Corporation 10.3791/50951

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

Adamopoulou, Eleni; Tenzer, Stefan; Hillen, Nina; Klug, Paul; Rota, Ioanna A.; Tietz, Silvia; Gebhardt, Madlen; Stevanovic, Stefan; Schild, Hansjörg; Tolosa, Eva; Melms, Arthur; Stoeckle, Christina (2013). Exploring the MHC-peptide matrix of central tolerance in the human thymus. Nature communications, 4(2039), p. 2039. Nature Publishing Group 10.1038/ncomms3039

Stoeckle, C.; Simon, Hans-Uwe (2013). CD8(+) T cells producing IL-3 and IL-5 in non-IgE-mediated eosinophilic diseases. Allergy, 68(12), pp. 1622-1628. Wiley-Blackwell 10.1111/all.12311

Stoeckle, Christina; Quecke, Paula; Rückrich, Thomas; Burster, Timo; Reich, Michael; Weber, Ekkehard; Kalbacher, Hubert; Driessen, Christoph; Melms, Arthur; Tolosa, Eva (2012). Cathepsin S dominates autoantigen processing in human thymic dendritic cells. Journal of autoimmunity, 38(4), pp. 332-43. Amsterdam: Elsevier 10.1016/j.jaut.2012.02.003

Lammel, Verena; Stoeckle, Christina; Padberg, Barbara; Zweifel, Roland; Kienle, Dirk L; Reinhart, Walter H; Simon, Hans-Uwe (2012). Hypereosinophilia driven by GM-CSF in large-cell carcinoma of the lung. Lung cancer, 76(3), pp. 493-5. Amsterdam: Elsevier 10.1016/j.lungcan.2012.02.014

Geering Truffer, Barbara; Schmidt-Mende, Jan; Federzoni, Elena; Stoeckle, Christina; Simon, Hans-Uwe (2011). Protein overexpression following lentiviral infection of primary mature neutrophils is due to pseudotransduction. Journal of immunological methods, 373(1-2), pp. 209-18. Amsterdam: Elsevier 10.1016/j.jim.2011.08.024

Sevenich, Lisa; Hagemann, Sascha; Stoeckle, Christina; Tolosa, Eva; Peters, Christoph; Reinheckel, Thomas (2010). Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice. Biochimie, 92(11), pp. 1674-80. Paris: Elsevier Masson SAS 10.1016/j.biochi.2010.03.014

Seizer, Peter; Schiemann, Susanne; Merz, Tobias; Daub, Karin; Bigalke, Boris; Stellos, Konstantinos; Müller, Iris; Stöckle, Christina; Müller, Karin; Gawaz, Meinrad; May, Andreas E (2010). CD36 and macrophage scavenger receptor a modulate foam cell formation via inhibition of lipid-laden platelet phagocytosis. Seminars in thrombosis and hemostasis, 36(2), pp. 157-62. New York, N.Y.: Thieme Medical Publishers 10.1055/s-0030-1251499

Luther, Claudia; Adamopoulou, Eleni; Stoeckle, Christina; Brucklacher-Waldert, Verena; Rosenkranz, Daniela; Stoltze, Lars; Lauer, Sigrid; Poeschel, Simone; Melms, Arthur; Tolosa, Eva (2009). Prednisolone treatment induces tolerogenic dendritic cells and a regulatory milieu in myasthenia gravis patients. Journal of immunology, 183(2), pp. 841-8. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0802046

Stoeckle, Christina; Gouttefangeas, Cécile; Hammer, Michael; Weber, Ekkehard; Melms, Arthur; Tolosa, Eva (2009). Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs. Experimental hematology, 37(2), pp. 266-75. New York, N.Y.: Elsevier 10.1016/j.exphem.2008.10.011

Stoeckle, Christina; Sommandas, Vinod; Adamopoulou, Eleni; Belisle, Kurt; Schiekofer, Stephan; Melms, Arthur; Weber, Ekkehard; Driessen, Christoph; Boehm, Bernhard O; Tolosa, Eva; Burster, Timo (2009). Cathepsin G is differentially expressed in primary human antigen-presenting cells. Cellular immunology, 255(1-2), pp. 41-5. San Diego, Calif.: Elsevier 10.1016/j.cellimm.2008.10.001

Stoeckle, Christina; Tolosa, Eva (2009). Antigen Processing and Presentation in Multiple Sclerosis. Results and problems in cell differentiation, 51, pp. 149-172. Berlin: Springer

Stoeckle, Christina; Gleske, Anne-Kathrin (2009). Immunotherapy: from basic research to clinical applications. Cancer immunology, immunotherapy, 58(7), pp. 1129-36. Heidelberg: Springer 10.1007/s00262-008-0544-z

Miescher-Granger, Sylvia M.

von Gunten, Stephan; Vogel, Monique; Schaub, Alexander; Stadler, Beda M; Miescher, Sylvia; Crocker, Paul R; Simon, Hans-Uwe (2007). Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. Journal of allergy and clinical immunology, 119(4), pp. 1005-11. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.01.023

Minier, Frédéric

Baur, Roland; Minier, Frédéric; Sigel, Erwin (2006). A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits. FEBS letters, 580(6), pp. 1616-20. Amsterdam: Elsevier 10.1016/j.febslet.2006.02.002

Moreno Bermudez, Josue Manuel

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Morshed, Mahbubul

Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x

Morshed, Md. Mahbubul

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Mullis, Primus-Eugen

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Petkovic, Vibor; Salemi, Souzan; Vassella, Erik; Karamitopoulou-Diamantis, Evanthia; Meinhardt, Udo J; Flück, Christa E; Mullis, Primus E (2007). Leydig-cell tumour in children: variable clinical presentation, diagnostic features, follow-up and genetic analysis of four cases. Hormone research, 67(2), pp. 89-95. Basel: Karger 10.1159/000096356

Salemi, Souzan; Yousefi, Shida; Eblé, Andrée; Deladoëy, Johnny; Mullis, Primus E (2006). Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis. Hormone research, 65(3), pp. 132-41. Basel: Karger 10.1159/000091607

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Müller, Beatrice Ursula

Rizzi, Mattia; Tschan, Mario P; Britschgi, Christian; Britschgi, Adrian; Hügli, Barbara; Grob, Tobias J; Leupin, Nicolas; Mueller, Beatrice U; Simon, Hans-Uwe; Ziemiecki, Andrew; Torbett, Bruce E; Fey, Martin F; Tobler, Andreas (2007). The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Journal of leukocyte biology, 81(6), pp. 1599-608. Bethesda, Md.: Society for Leukocyte Biology 10.1189/jlb.0606400

Müller, Christoph

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

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Saliakoura, Maria; Rossi Sebastiano, Matteo; Nikdima, Ioanna; Pozzato, Chiara; Konstantinidou, Georgia (2022). Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy. Journal of experimental & clinical cancer research, 41(1), p. 16. BioMed Central 10.1186/s13046-021-02231-y

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April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Safroneeva, Ekaterina

Bon, Lorenz; Safroneeva, Ekaterina; Bussmann, Christian; Biedermann, Luc; Schreiner, Philipp; Vavricka, Stephan R; Schoepfer, Alain M; McCright-Gill, Talaya; Simon, Hans-Uwe; Straumann, Alex; Chehade, Mirna; Greuter, Thomas (2022). Close follow-up is associated with fewer stricture formation and results in earlier detection of histological relapse in the long-term management of eosinophilic esophagitis. United European gastroenterology journal, 10(3), pp. 308-318. Wiley 10.1002/ueg2.12216

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. (In Press). Allergy Wiley 10.1111/all.15233

Schoepfer, Alain M; Henchoz, Sarah; Biedermann, Luc; Schreiner, Philipp; Greuter, Thomas; Reinhard, Antoine; Senn, Jonduri; Franke, Annett; Burri, Emanuel; Juillerat, Pascal; Simon, Hans-Uwe; Straumann, Alex; Safroneeva, Ekaterina; Godat, Sébastien (2021). Technical feasibility, clinical effectiveness, and safety of esophageal stricture dilation using a novel endoscopic attachment cap in adults with eosinophilic esophagitis. Gastrointestinal endoscopy, 94(5), 912-919.e2. Elsevier 10.1016/j.gie.2021.05.017

Biedermann, Luc; Holbreich, Mark; Atkins, Dan; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Hirano, Ikuo; Gonsalves, Nirmala; Greuter, Thomas; Katzka, David A; De Rooij, Willemijn; Safroneeva, Ekaterina; Schoepfer, Alain; Schreiner, Philipp; Simon, Dagmar; Simon, Hans Uwe; Warners, Marijn; Bredenoord, Albert-Jan; Straumann, Alex (2021). Food-induced Immediate Response of the Esophagus - a newly identified Syndrome in Patients with Eosinophilic Esophagitis. Allergy, 76(1), pp. 339-347. Wiley-Blackwell 10.1111/all.14495

Schreiner, Philipp; Meissgeier, Silas; Safroneeva, Ekaterina; Greuter, Thomas; Rogler, Gerhard; Schoepfer, Alain; Simon, Dagmar; Simon, Hans-Uwe; Biedermann, Luc; Straumann, Alex (2020). Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology, 18(11), pp. 2456-2462. Elsevier 10.1016/j.cgh.2019.11.057

Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493

Bussmann, Christian; Schoepfer, Alain M; Safroneeva, Ekaterina; Haas, Nadine; Godat, Sébastien; Sempoux, Christine; Simon, Hans-Uwe; Straumann, Alex (2016). Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy, 48(12), pp. 1069-1075. Thieme 10.1055/s-0042-117274

Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879

Schoepfer, Alain M.; Safroneeva, Ekaterina; Bussmann, Christian; Kuchen, Tanja; Portmann, Susanne; Simon, Hans-Uwe; Straumann, Alex (2013). Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation in a time-dependent manner. Gastroenterology, 145(6), 1230-1236.e2. Elsevier 10.1053/j.gastro.2013.08.015

Salemi, Souzan

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Berent-Maoz, Beata; Salemi, Souzan; Mankuta, David; Simon, Hans-Uwe; Levi-Schaffer, Francesca (2010). Human mast cells express intracellular TRAIL. Cellular immunology, 262(2), pp. 80-3. San Diego, Calif.: Elsevier 10.1016/j.cellimm.2010.02.003

Petkovic, Vibor; Salemi, Souzan; Vassella, Erik; Karamitopoulou-Diamantis, Evanthia; Meinhardt, Udo J; Flück, Christa E; Mullis, Primus E (2007). Leydig-cell tumour in children: variable clinical presentation, diagnostic features, follow-up and genetic analysis of four cases. Hormone research, 67(2), pp. 89-95. Basel: Karger 10.1159/000096356

Salemi, Souzan; Aeschlimann, Andre; Wollina, Uwe; Gay, Renate E; Michel, Beat A; Gay, Steffen; Sprott, Haiko (2007). Up-regulation of delta-opioid receptors and kappa-opioid receptors in the skin of fibromyalgia patients. Arthritis & rheumatism, 56(7), pp. 2464-6. Hoboken, N.J.: Wiley-Blackwell 10.1002/art.22735

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Saliakoura, Maria

Saliakoura, Maria; Rossi Sebastiano, Matteo; Nikdima, Ioanna; Pozzato, Chiara; Konstantinidou, Georgia (2022). Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy. Journal of experimental & clinical cancer research, 41(1), p. 16. BioMed Central 10.1186/s13046-021-02231-y

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Saliakoura, Maria; Rossi, Sebastiano Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Saliakoura, Maria; Reynoso-Moreno, Inés; Pozzato, Chiara; Rossi Sebastiano, Matteo; Galié, Mirco; Gertsch, Jürg; Konstantinidou, Georgia (2020). The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Oncogene, 39(14), pp. 2948-2960. Springer Nature 10.1038/s41388-020-1196-5

Sandbaumhüter, Friederike Andrea

Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488

Saurer, Leslie

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Schaffner, Thomas

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Schaller, André

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Schefold, Jörg Christian

Spinetti, Thibaud; Meisel, Christian; von Gunten, Stephan; Schefold, Joerg C. (2020). Immune biomarker-based enrichment in sepsis trials. Critical care, 24(1), p. 58. BioMed Central 10.1186/s13054-020-2774-1

Schindewolf, Marc

Sebastian, Tim; Barco, Stefano; Engelberger, Rolf P; Spirk, David; Schindewolf, Marc; Baumann, Frederic; Baumgartner, Iris; Kucher, Nils (2020). Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. European journal of vascular and endovascular surgery EJVES, 60(3), pp. 443-450. Elsevier 10.1016/j.ejvs.2020.05.011

Schittny, Johannes

Peter, Andreas B.; Schittny, Johannes C.; Niggli, Verena; Reuter, Harald; Sigel, Erwin (1991). The polarized distribution of poly(A+)-mRNA-induced functional ion channels in the Xenopus oocyte plasma membrane is prevented by anticytoskeletal drugs. Journal of cell biology, 114(3), pp. 455-464. Rockefeller Institute Press

Schlapbach, Christoph

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

Schmid, Ines

Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Eveline; Schmid, Ines; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S and Simon, Hans-Uwe (2015). Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular cell, 57(6), pp. 1011-1021. Cell Press 10.1016/j.molcel.2015.01.026

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Schmid, Ralph

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Saliakoura, Maria; Rossi, Sebastiano Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Schmidt, Jan

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Schneider, Christoph

Späth, Peter Julius; Schneider, Christoph; von Gunten, Stephan (2017). Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations. Archivum immunologiae et therapiae experimentalis, 65(3), pp. 215-231. Springer 10.1007/s00005-016-0422-x

Schneider, Christoph; Illi, Marlies; Lötscher, Marius; Wehrli, Marc; von Gunten, Stephan (2017). Isolation of Antibodies from Human Plasma, Saliva, Breast Milk, and Gastrointestinal Fluid. Methods in molecular biology, 1643, pp. 23-31. Springer 10.1007/978-1-4939-7180-0_3

Quast, Isaak; Keller, Christian W; Weber, Patrick; Schneider, Christoph; von Gunten, Stephan; Lünemann, Jan D (2016). Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation. Journal of neuroinflammation, 13, p. 42. BioMed Central 10.1186/s12974-016-0506-x

(2016). Protein-carbohydrate interactions in the human immune system (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Scholz, Irene

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Schorer, Myriam Fabiola

Schorer, Myriam Fabiola; Simon, Dagmar (2016). Innate immune system crosstalk: Eosinophils mediate immune modulation of dendritic cells through exosomes as shuttle vectors of miRNA (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/​jimmunol.1400028

von Gunten, Stephan; Schorer, Myriam Fabiola; Kollarik, M.; Beisswenger, C.; Lepper, P. M. (2013). Mechanisms and potential therapeutic targets in allergic inflammation: recent insights. Allergy, 68(12), pp. 1487-1498. Wiley-Blackwell 10.1111/all.12312

Schwalm, Stephanie

Beyer, Sandra; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2018). Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. Cellular physiology and biochemistry, 47(6), pp. 2522-2533. Karger 10.1159/000491625

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Wünsche, Christin; Koch, Alexander; Goldschmeding, Roel; Schwalm, Stephanie; Meyer Zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2015). Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1851(5), pp. 519-526. Elsevier 10.1016/j.bbalip.2015.01.003

Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2010). Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation. British journal of pharmacology, 160(7), pp. 1641-51. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.00818.x

Förster, Ankathrin; Emmler, Tanja; Schwalm, Stephanie; Ebadi, Mahsa; Heringdorf, Dagmar Meyer Zu; Nieuwenhuis, Barbara; Kleuser, Burkhardt; Huwiler, Andrea; Pfeilschifter, Josef (2010). Glucocorticoids protect renal mesangial cells from apoptosis by increasing cellular sphingosine-1-phosphate. Kidney international, 77(10), pp. 870-9. New York, N.Y.: Nature Publishing Group 10.1038/ki.2010.62

Schöpfer, Alain

Straumann, Alex; Bussmann, Christian; Zuber, Markus; Vannini, Simone; Simon, Hans-Uwe; Schoepfer, Alain (2008). Eosinophilic esophagitis: analysis of food impaction and perforation in 251 adolescent and adult patients. Clinical gastroenterology and hepatology, 6(5), pp. 598-600. Philadelphia, Pa.: Elsevier 10.1016/j.cgh.2008.02.003

Schürch, Christian

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Schürch, Stefan

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Sebastian, Tim

Sebastian, Tim; Spirk, David; Engelberger, Rolf P; Dopheide, Jörn F.; Baumann, Frederic A; Barco, Stefano; Spescha, Rebecca; Leeger, Claudia; Kucher, Nils (2019). Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome. Thrombosis and haemostasis, 119(12), pp. 2064-2073. Thieme 10.1055/s-0039-1697955

Seiler, Kristina

Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

Siegrist, Mark

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Sigel, Erwin

Sigel, E; Baur, R; Boulineau, N; Minier, F (2006). Impact of subunit positioning on GABAA receptor function. Biochemical Society transactions, 34(Pt 5), pp. 868-71. London: Portland Press

Baur, Roland; Minier, Frédéric; Sigel, Erwin (2006). A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits. FEBS letters, 580(6), pp. 1616-20. Amsterdam: Elsevier 10.1016/j.febslet.2006.02.002

Peter, Andreas B.; Schittny, Johannes C.; Niggli, Verena; Reuter, Harald; Sigel, Erwin (1991). The polarized distribution of poly(A+)-mRNA-induced functional ion channels in the Xenopus oocyte plasma membrane is prevented by anticytoskeletal drugs. Journal of cell biology, 114(3), pp. 455-464. Rockefeller Institute Press

Silbernagel, Günther

Silbernagel, Günther; Spirk, David; Hager, Adrian; Baumgartner, Iris; Kucher, Nils (2016). Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial. Journal of the American Heart Association, 5(7), pp. 1-7. American Heart Association 10.1161/JAHA.116.003776

Simillion, Cedric André Marie

Haas, Quentin; Simillion, Cedric André Marie; von Gunten, Stephan (2018). A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future? Frontiers in oncology, 8, p. 68. Frontiers Research Foundation 10.3389/fonc.2018.00068

Simon, Dagmar

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Klapan, Kim; Simon, Dagmar; Karaulov, Alexander; Gomzikova, Marina; Rizvanov, Albert; Yousefi, Shida; Simon, Hans-Uwe (2022). Autophagy and Skin Diseases. Frontiers in Pharmacology, 13, p. 844756. Frontiers 10.3389/fphar.2022.844756

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. (In Press). Allergy Wiley 10.1111/all.15233

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Radonjic-Hoesli, Susanne; Brüggen, Marie-Charlotte; Feldmeyer, Laurence; Simon, Hans-Uwe; Simon, Dagmar (2021). Eosinophils in skin diseases. Seminars in immunopathology, 43(3), pp. 393-409. Springer 10.1007/s00281-021-00868-7

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Biedermann, Luc; Holbreich, Mark; Atkins, Dan; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Hirano, Ikuo; Gonsalves, Nirmala; Greuter, Thomas; Katzka, David A; De Rooij, Willemijn; Safroneeva, Ekaterina; Schoepfer, Alain; Schreiner, Philipp; Simon, Dagmar; Simon, Hans Uwe; Warners, Marijn; Bredenoord, Albert-Jan; Straumann, Alex (2021). Food-induced Immediate Response of the Esophagus - a newly identified Syndrome in Patients with Eosinophilic Esophagitis. Allergy, 76(1), pp. 339-347. Wiley-Blackwell 10.1111/all.14495

Holvoet, Sébastien; Nutten, Sophie; Dupuis, Lénaïck; Donnicola, Dominique; Bourdeau, Tristan; Hughes-Formella, Betsy; Simon, Dagmar; Simon, Hans-Uwe; Carvalho, Ryan S.; Spergel, Jonathan M.; Koletzko, Sibylle; Blanchard, Carine (2021). Partially Hydrolysed Whey-Based Infant Formula Improves Skin Barrier Function. Nutrients, 13(9), p. 3113. Molecular Diversity Preservation International MDPI 10.3390/nu13093113

Schreiner, Philipp; Meissgeier, Silas; Safroneeva, Ekaterina; Greuter, Thomas; Rogler, Gerhard; Schoepfer, Alain; Simon, Dagmar; Simon, Hans-Uwe; Biedermann, Luc; Straumann, Alex (2020). Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology, 18(11), pp. 2456-2462. Elsevier 10.1016/j.cgh.2019.11.057

Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Maurer, Marcus; Eyerich, Kilian; Eyerich, Stefanie; Ferrer, Marta; Gutermuth, Jan; Hartmann, Karin; Jakob, Thilo; Kapp, Alexander; Kolkhir, Pavel; Larenas-Linnemann, Désirée; Park, Hae-Sim; Pejler, Gunnar; Sánchez-Borges, Mario; Schäkel, Knut; Simon, Dagmar; Simon, Hans-Uwe; Weller, Karsten; Zuberbier, Torsten; Metz, Martin (2020). Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(5), pp. 321-333. Karger 10.1159/000507218

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Simon, Dagmar; Simon, Hans-Uwe (2020). Relationship of skin barrier breakdown and eosinophilic esophagitis. Journal of allergy and clinical immunology, 145(1), 90-92.e1. Elsevier 10.1016/j.jaci.2019.11.005

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Karra, Laila; Gangwar, Roopesh Singh; Puzzovio, Pier Giorgio; Fyhrquist, Nanna; Minai-Fleminger, Yael; Landolina, Nadine; Simon, Hans-Uwe; Alenius, Harri; Leibovici, Vera; Simon, Dagmar; Levi-Schaffer, Francesca (2019). CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response. Allergy, 74(7), pp. 1377-1380. Wiley 10.1111/all.13724

Simon, Dagmar; Simon, Hans-Uwe (2019). Therapeutic strategies for eosinophilic dermatoses. Current opinion in pharmacology, 46, pp. 29-33. Elsevier 10.1016/j.coph.2019.01.002

Simon, Dagmar; Wollenberg, Andreas; Renz, Harald; Simon, Hans-Uwe (2019). Atopic Dermatitis: Collegium Internationale Allergologicum (CIA) Update 2019. International archives of allergy and immunology, 178(3), pp. 207-218. Karger 10.1159/000497383

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Simon, Dagmar; Simon, Hans-Uwe (2019). The role of pharmacists (In Press). In: Brockow, Brockow; Mortz, Charlotte (eds.) Global atlas of skin allergy (pp. 276-278). European academy of allergy and clinical immunology

Sauser, Julien; Nutten, Sophie; de Groot, Nanda; Pecquet, Sophie; Simon, Dagmar; Simon, Hans-Uwe; Spergel, Jonathan M; Koletzko, Sibylle; Blanchard, Carine (2018). Partially Hydrolyzed Whey Infant Formula: Literature Review on Effects on Growth and the Risk of Developing Atopic Dermatitis in Infants from the General Population. International archives of allergy and immunology, 177(2), pp. 123-134. Karger 10.1159/000489861

Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J; Arron, Joseph R; Bochner, Bruce S; Collins, Margaret H; Kahn, Jean-Emmanuel; Fulkerson, Patricia C; Gleich, Gerald J; Gopal-Srivastava, Rashmi; Jacobsen, Elizabeth A; Leiferman, Kristen M; Francesca, Levi-Schaffer; Mathur, Sameer K; Minnicozzi, Michael; Prussin, Calman; Rothenberg, Marc E; Roufosse, Florence; Sable, Kathleen; Simon, Dagmar; ... (2018). Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of leukocyte biology, 104(1), pp. 69-83. Society for Leukocyte Biology 10.1002/JLB.5MR0118-028R

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493

Simon, Dagmar; Page, Basile; Vogel, Monique; Bussmann, Christian; Blanchard, Carine; Straumann, Alex; Simon, Hans-Uwe (2018). Evidence of an abnormal epithelial barrier in active, untreated and corticosteroid-treated eosinophilic esophagitis. Allergy, 73(1), pp. 239-247. Wiley-Blackwell 10.1111/all.13244

Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

Blanchard, C.; Simon, Dagmar; Schoepfer, A.; Straumann, A.; Simon, Hans-Uwe (2017). Eosinophilic esophagitis: unclear roles of IgE and eosinophils. Journal of internal medicine, 281(5), pp. 448-457. Blackwell Scientific Publications 10.1111/joim.12568

Simon, Dagmar; Straumann, Alex; Schoepfer, Alain M; Simon, Hans-Uwe (2017). Current concepts in eosinophilic esophagitis. Allergo journal international, 26(7), pp. 258-266. Springer 10.1007/s40629-017-0037-8

Bieber, T; Akdis, C; Lauener, R; Traidl-Hoffmann, C; Schmid-Grendelmeier, P; Schäppi, G; Allam, J-P; Apfelbacher, C; Augustin, M; Beck, L; Biedermann, T; Braun-Fahrländer, C; Chew, F T; Clavel, T; Crameri, R; Darsow, U; Deleuran, M; Dittlein, D; Duchna, H-W; Eichenfeld, L; ... (2016). Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine. Allergy, 71(5), pp. 588-592. Wiley-Blackwell 10.1111/all.12857

Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879

Simon, Dagmar; Cianferoni, A; Spergel, J M; Aceves, S; Holbreich, M; Venter, C; Rothenberg, M E; Terreehorst, I; Muraro, A; Lucendo, A J; Schoepfer, A; Straumann, A; Simon, Hans-Uwe (2016). Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity. Allergy, 71(5), pp. 611-620. Wiley-Blackwell 10.1111/all.12846

Simon, Hans-Uwe; Simon, Dagmar (2016). Leserbrief zum Beitrag Hypereosinophilie. Swiss medical weekly, 16(4), p. 104. EMH Schweizerischer Ärzteverlag

Simon, Hans-Uwe; Yousefi, Shida; Simon, Dagmar (2016). Basophils can form extracellular DNA traps independent of a functional NADPH oxidase. In: Maurer, Markus; Behrendt, Heidrum (eds.) Allergies: Current challenges and solutions. Proceedings of the 30th Symposium of the Collegium Internationale Allergologicum (CIA) (pp. 67-70). Ospedaletto (Pisa): Pacini editore Medicina

Schorer, Myriam Fabiola; Simon, Dagmar (2016). Innate immune system crosstalk: Eosinophils mediate immune modulation of dendritic cells through exosomes as shuttle vectors of miRNA (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Simon, Dagmar; Straumann, A.; Simon, Hans-Uwe (2014). Eosinophilic esophagitis and allergy. Digestive diseases, 32(1-2), pp. 30-33. Karger 10.1159/000357006

Simon, D.; Aeberhard, C.; Erdemoglu, Y.; Simon, H.-U. (2014). Th17 cells and tissue remodeling in atopic and contact dermatitis. Allergy, 69(1), pp. 125-131. Wiley-Blackwell 10.1111/all.12351

Houriet, C.; Simon, H.-U.; Simon, D. (2014). Hypereosinophilic Syndromes. Aktuelle Dermatologie, 40(4), pp. 127-132. Thieme 10.1055/s-0034-1365078

Ring, J.; Akdis, C.; Lauener, R.; Schäppi, G.; Traidl-Hoffmann, C.; Akdis, M.; Ammann, W.; Behrendt, H.; Bieber, T.; Biedermann, T.; Bienenstock, J.; Blaser, K.; Braun-Fahrländer, C.; Brocknow, K.; Buters, J.; Crameri, R.; Darsow, U.; Denburg, J.A.; Eyerich, K.; Frei, R.; ... (2014). Global Allergy Forum and Second Davos Declaration 2013 Allergy: Barriers to cure - challenges and actions to be taken. Allergy, 69(8), pp. 978-982. Wiley-Blackwell 10.1111/all.12406

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2013). Glucocorticoids in autoimmune bullous diseases: are neutrophils the key cellular target? Journal of Investigative Dermatology, 133(10), pp. 2314-2315. Nature Publishing 10.1038/jid.2013.205

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2013). Extracellular DNA traps in allergic, infectzious, and autoimmune diseases. Allergy, 68(4), pp. 409-416. Wiley-Blackwell 10.1111/all.12111

Simon, D.; Straumann, A.; Dahinden, C.; Simon, H.-U. (2013). Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis. Allergy, 68(7), pp. 945-948. Wiley-Blackwell 10.1111/all.12157

Simon, Dagmar; Simon, Hans-Uwe (2013). Eosinophilic skin diseases. In: Lee, James J.; Rosenberg, Helene F. (eds.) Eosinophils in health and diseases (pp. 442-448). Amsterdam: Elsevier

von Gunten, S; Marsland, B J; von Garnier, C; Simon, D (2012). Update in clinical allergy and immunology. Allergy, 67(12), pp. 1491-500. Oxford: Wiley-Blackwell 10.1111/all.12067

Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2012). Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease. Current opinion in immunology, 24(6), pp. 736-9. Kidlington, UK: Elsevier 10.1016/j.coi.2012.08.010

Wechsler, Michael E; Fulkerson, Patricia C; Bochner, Bruce S; Gauvreau, Gail M; Gleich, Gerald J; Henkel, Tim; Kolbeck, Roland; Mathur, Sameer K; Ortega, Hector; Patel, Jatin; Prussin, Calman; Renzi, Paolo; Rothenberg, Marc E; Roufosse, Florence; Simon, Dagmar; Simon, Hans-Uwe; Wardlaw, Andrew; Weller, Peter F; Klion, Amy D (2012). Novel targeted therapies for eosinophilic disorders. Journal of allergy and clinical immunology, 130(3), pp. 563-71. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.07.027

Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x

Simon, Dagmar; Simon, Hans-Uwe (2012). New drug targets in atopic dermatitis. Chemical immunology and allergy, 96, pp. 126-131. Basel: Karger

Straumann, A; Aceves, S S; Blanchard, C; Collins, M H; Furuta, G T; Hirano, I; Schoepfer, A M; Simon, D; Simon, H-U (2012). Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy, 67(4), pp. 477-90. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02787.x

Roth, N; Städler, S; Lemann, M; Hösli, S; Simon, H-U; Simon, D (2011). Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. Allergy, 66(11), pp. 1477-86. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02694.x

Simon, Dagmar; Hoesli, Susanne; Roth, Nina; Staedler, Simon; Yousefi, Shida; Simon, Hans-Uwe (2011). Eosinophil extracellular DNA traps in skin diseases. Journal of allergy and clinical immunology, 127(1), pp. 194-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.11.002

Salemi, S; Yousefi, S; Simon, D; Schmid, I; Moretti, L; Scapozza, L; Simon, H-U (2009). A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. Allergy, 64(6), pp. 913-8. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.01943.x

Ogbogu, Princess U; Bochner, Bruce S; Butterfield, Joseph H; Gleich, Gerald J; Huss-Marp, Johannes; Kahn, Jean Emmanuel; Leiferman, Kristin M; Nutman, Thomas B; Pfab, Florian; Ring, Johannes; Rothenberg, Marc E; Roufosse, Florence; Sajous, Marie-Helene; Sheikh, Javed; Simon, Dagmar; Simon, Hans-Uwe; Stein, Miguel L; Wardlaw, Andrew; Weller, Peter F and Klion, Amy D (2009). Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. Journal of allergy and clinical immunology, 124(6), 1319-25.e3. St. Louis, Mo.: Mosby 10.1016/j.jaci.2009.09.022

Simon, Dagmar; Salemi, Souzan; Yousefi, Shida; Simon, Hans-Uwe (2008). Primary resistance to imatinib in Fip1-like 1-platelet-derived growth factor receptor alpha-positive eosinophilic leukemia. Journal of allergy and clinical immunology, 121(4), pp. 1054-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.027

Kostylina, G; Simon, D; Fey, M F; Yousefi, S; Simon, H U (2008). Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A). Cell death and differentiation, 15(1), pp. 134-42. Basingstoke: Nature Publishing Group 10.1038/sj.cdd.4402238

Simon, Dagmar; Wittwer, Jennifer; Kostylina, Ganna; Buettiker, Urs; Simon, Hans-Uwe; Yawalkar, Nikhil (2008). Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema. Journal of allergy and clinical immunology, 122(2), pp. 423-4. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.010

Simon, Dagmar; Hösli, Susanne; Kostylina, Ganna; Yawalkar, Nikhil; Simon, Hans-Uwe (2008). Anti-CD20 (rituximab) treatment improves atopic eczema. Journal of allergy and clinical immunology, 121(1), pp. 122-8. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.016

Hassan, Akmal S; Simon, Dagmar; Simon, Hans-Uwe; Braathen, Lasse R; Yawalkar, Nikhil (2007). Efalizumab-associated papular psoriasis. Archives of dermatology, 143(7), pp. 900-6. Chicago, Ill.: American Medical Association 10.1001/archderm.143.7.900

Simon, D; Braathen, L R; Simon, H-U (2007). Increased lipopolysaccharide-induced tumour necrosis factor-alpha, interferon-gamma and interleukin-10 production in atopic dermatitis. British journal of dermatology, 157(3), pp. 583-6. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2007.08050.x

Simon, Dagmar; Simon, Hans-Uwe (2007). Eosinophilic disorders. Journal of allergy and clinical immunology, 119(6), 1291-300; quiz 1301-2. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.02.010

Simon, D; Braathen, L R; Simon, H-U (2007). [Anti-interleukin-5 therapy for eosinophilic diseases]. Hautarzt, 58(2), 122, 124-7. Heidelberg: Springer-Verlag 10.1007/s00105-006-1273-x

Vassina, Ekatherina M; Yousefi, Shida; Simon, Dagmar; Zwicky, Caroline; Conus, Sébastien; Simon, Hans-Uwe (2006). cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. European journal of immunology, 36(7), pp. 1975-84. Weinheim: Wiley-VCH 10.1002/eji.200635943

Simon, D; Straumann, A; Wenk, A; Spichtin, H; Simon, H-U; Braathen, L R (2006). Eosinophilic esophagitis in adults--no clinical relevance of wheat and rye sensitizations. Allergy, 61(12), pp. 1480-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01224.x

Simon, Dagmar; Lindberg, Raija L P; Kozlowski, Evelyne; Braathen, Lasse R; Simon, Hans-Uwe (2006). Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions. Experimental dermatology, 15(6), pp. 441-6. Oxford: Blackwell 10.1111/j.0906-6705.2006.00428.x

Simon, Hans-Uwe

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Bon, Lorenz; Safroneeva, Ekaterina; Bussmann, Christian; Biedermann, Luc; Schreiner, Philipp; Vavricka, Stephan R; Schoepfer, Alain M; McCright-Gill, Talaya; Simon, Hans-Uwe; Straumann, Alex; Chehade, Mirna; Greuter, Thomas (2022). Close follow-up is associated with fewer stricture formation and results in earlier detection of histological relapse in the long-term management of eosinophilic esophagitis. United European gastroenterology journal, 10(3), pp. 308-318. Wiley 10.1002/ueg2.12216

Fallegger, Angela; Priola, Martina; Artola-Borán, Mariela; Núñez, Nicolás Gonzalo; Wild, Sebastian; Gurtner, Alessandra; Becher, Burkhard; Yousefi, Shida; Simon, Hans-Uwe; Arnold, Isabelle C; Müller, Anne (2022). TGF-β production by eosinophils drives the expansion of peripherally induced neuropilin- RORγt+ regulatory T-cells during bacterial and allergen challenge. Mucosal immunology, 15(3), pp. 504-514. Springer Nature 10.1038/s41385-022-00484-0

Klapan, Kim; Simon, Dagmar; Karaulov, Alexander; Gomzikova, Marina; Rizvanov, Albert; Yousefi, Shida; Simon, Hans-Uwe (2022). Autophagy and Skin Diseases. Frontiers in Pharmacology, 13, p. 844756. Frontiers 10.3389/fphar.2022.844756

Artola-Borán, Mariela; Fallegger, Angela; Priola, Martina; Jeske, Rima; Waterboer, Tim; Dohlman, Anders B; Shen, Xiling; Wild, Sebastian; He, Jiazhuo; Levesque, Mitchell P; Yousefi, Shida; Simon, Hans-Uwe; Cheng, Phil F; Müller, Anne (2022). Mycobacterial infection aggravates Helicobacter pylori-induced gastric preneoplastic pathology by redirection of de novo induced Treg cells. Cell reports, 38(6), p. 110359. Cell Press 10.1016/j.celrep.2022.110359

Cristinziano, Leonardo; Modestino, Luca; Antonelli, Alessandro; Marone, Gianni; Simon, Hans-Uwe; Varricchi, Gilda; Galdiero, Maria Rosaria (2022). Neutrophil extracellular traps in cancer. Seminars in cancer biology, 79, pp. 91-104. Elsevier 10.1016/j.semcancer.2021.07.011

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. (In Press). Allergy Wiley 10.1111/all.15233

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Schoepfer, Alain M; Henchoz, Sarah; Biedermann, Luc; Schreiner, Philipp; Greuter, Thomas; Reinhard, Antoine; Senn, Jonduri; Franke, Annett; Burri, Emanuel; Juillerat, Pascal; Simon, Hans-Uwe; Straumann, Alex; Safroneeva, Ekaterina; Godat, Sébastien (2021). Technical feasibility, clinical effectiveness, and safety of esophageal stricture dilation using a novel endoscopic attachment cap in adults with eosinophilic esophagitis. Gastrointestinal endoscopy, 94(5), 912-919.e2. Elsevier 10.1016/j.gie.2021.05.017

Ackermann, Maximilian; Anders, Hans-Joachim; Bilyy, Rostyslav; Bowlin, Gary L; Daniel, Christoph; De Lorenzo, Rebecca; Egeblad, Mikala; Henneck, Timo; Hidalgo, Andrés; Hoffmann, Markus; Hohberger, Bettina; Kanthi, Yogendra; Kaplan, Mariana J; Knight, Jason S; Knopf, Jasmin; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; Mahajan, Aparna; Manfredi, Angelo A; ... (2021). Patients with COVID-19: in the dark-NETs of neutrophils. Cell death and differentiation, 28(11), pp. 3125-3139. Springer Nature 10.1038/s41418-021-00805-z

Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M K; Choi, Mary E; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; ... (2021). Autophagy in major human diseases. The EMBO journal, 40(19), e108863. EMBO Press 10.15252/embj.2021108863

Delemarre, Tim; Bochner, Bruce S; Simon, Hans-Uwe; Bachert, Claus (2021). Rethinking neutrophils and eosinophils in chronic rhinosinusitis. Journal of allergy and clinical immunology, 148(2), pp. 327-335. Elsevier 10.1016/j.jaci.2021.03.024

Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Renz, Harald; Bachert, Claus; Berek, Claudia; Hamelmann, Eckard; Levi-Schaffer, Francesca; Raap, Ulrike; Simon, Hans-Uwe; Ploetz, Sabine; Taube, Christian; Valent, Peter; Voehringer, David; Werfel, Thomas; Zhang, Nan; Ring, Johannes (2021). Physiology and pathology of eosinophils: Recent developments: Summary of the Focus Workshop Organized by DGAKI. Scandinavian journal of immunology, 93(6), e13032. Wiley-Blackwell 10.1111/sji.13032

Radonjic-Hoesli, Susanne; Brüggen, Marie-Charlotte; Feldmeyer, Laurence; Simon, Hans-Uwe; Simon, Dagmar (2021). Eosinophils in skin diseases. Seminars in immunopathology, 43(3), pp. 393-409. Springer 10.1007/s00281-021-00868-7

Simon, Hans-Uwe (2021). The eosinophil and its role in physiology and disease: news and views. Seminars in immunopathology, 43(3), pp. 291-293. Springer 10.1007/s00281-021-00866-9

Valent, Peter; Degenfeld-Schonburg, Lina; Sadovnik, Irina; Horny, Hans-Peter; Arock, Michel; Simon, Hans-Uwe; Reiter, Andreas; Bochner, Bruce S (2021). Eosinophils and eosinophil-associated disorders: immunological, clinical, and molecular complexity. Seminars in immunopathology, 43(3), pp. 423-438. Springer 10.1007/s00281-021-00863-y

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Biedermann, Luc; Holbreich, Mark; Atkins, Dan; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Hirano, Ikuo; Gonsalves, Nirmala; Greuter, Thomas; Katzka, David A; De Rooij, Willemijn; Safroneeva, Ekaterina; Schoepfer, Alain; Schreiner, Philipp; Simon, Dagmar; Simon, Hans Uwe; Warners, Marijn; Bredenoord, Albert-Jan; Straumann, Alex (2021). Food-induced Immediate Response of the Esophagus - a newly identified Syndrome in Patients with Eosinophilic Esophagitis. Allergy, 76(1), pp. 339-347. Wiley-Blackwell 10.1111/all.14495

Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003

Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia; ... (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. Taylor & Francis 10.1080/15548627.2020.1797280

Wang, Xiaoliang; Avsec, Damjan; Obreza, Aleš; Yousefi, Shida; Mlinarič-Raščan, Irena; Simon, Hans-Uwe (2021). A Putative Serine Protease is Required to Initiate the RIPK3-MLKL-Mediated Necroptotic Death Pathway in Neutrophils. Frontiers in Pharmacology, 11, p. 614928. Frontiers 10.3389/fphar.2020.614928

Bruno, Andreina; Di Sano, Caterina; Simon, Hans-Uwe; Chanez, Pascal; Patti, Angelo Maria; Di Vincenzo, Serena; Dino, Paola; D'Esposito, Vittoria; Formisano, Pietro; Beguinot, Francesco; Pace, Elisabetta (2021). Leptin and TGF-β1 Downregulate PREP1 Expression in Human Adipose-Derived Mesenchymal Stem Cells and Mature Adipocytes. Frontiers in cell and developmental biology, 9, p. 700481. Frontiers 10.3389/fcell.2021.700481

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Holvoet, Sébastien; Nutten, Sophie; Dupuis, Lénaïck; Donnicola, Dominique; Bourdeau, Tristan; Hughes-Formella, Betsy; Simon, Dagmar; Simon, Hans-Uwe; Carvalho, Ryan S.; Spergel, Jonathan M.; Koletzko, Sibylle; Blanchard, Carine (2021). Partially Hydrolysed Whey-Based Infant Formula Improves Skin Barrier Function. Nutrients, 13(9), p. 3113. Molecular Diversity Preservation International MDPI 10.3390/nu13093113

von Gunten, Stephan; Simon, Hans-Uwe (2020). Linking glucocorticoid-induced osteoporosis to osteoimmunology. Cell death & disease, 11(12), p. 1026. Nature Publishing Group 10.1038/s41419-020-03250-x

Piacentini, Mauro; Shi, Yufang; Simon, Hans-Uwe (2020). 10 years of Cell Death & Disease. Cell death & disease, 11(12), p. 1064. Springer Nature 10.1038/s41419-020-03287-y

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Schreiner, Philipp; Meissgeier, Silas; Safroneeva, Ekaterina; Greuter, Thomas; Rogler, Gerhard; Schoepfer, Alain; Simon, Dagmar; Simon, Hans-Uwe; Biedermann, Luc; Straumann, Alex (2020). Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology, 18(11), pp. 2456-2462. Elsevier 10.1016/j.cgh.2019.11.057

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107

Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113

Simon, Hans-Uwe; Karaulov, Alexander V; Bachmann, Martin F. (2020). Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection. International archives of allergy and immunology, 181(8), pp. 624-628. Karger 10.1159/000509368

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007

Maurer, Marcus; Eyerich, Kilian; Eyerich, Stefanie; Ferrer, Marta; Gutermuth, Jan; Hartmann, Karin; Jakob, Thilo; Kapp, Alexander; Kolkhir, Pavel; Larenas-Linnemann, Désirée; Park, Hae-Sim; Pejler, Gunnar; Sánchez-Borges, Mario; Schäkel, Knut; Simon, Dagmar; Simon, Hans-Uwe; Weller, Karsten; Zuberbier, Torsten; Metz, Martin (2020). Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(5), pp. 321-333. Karger 10.1159/000507218

Müller, Ines; Strozyk, Elwira; Schindler, Sebastian; Beissert, Stefan; Oo, Htoo Zarni; Sauter, Thomas; Lucarelli, Philippe; Raeth, Sebastian; Hausser, Angelika; Al Nakouzi, Nader; Fazli, Ladan; Gleave, Martin E; Liu, He; Simon, Hans-Uwe; Walczak, Henning; Green, Douglas R; Bartek, Jiri; Daugaard, Mads; Kulms, Dagmar (2020). Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. Molecular cell, 77(5), 970-984.e7. Cell Press 10.1016/j.molcel.2019.12.023

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

He, Zhaoyue; Liu, He; Moch, Holger; Simon, Hans-Uwe (2020). Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Scientific reports, 10(1), p. 720. Springer Nature 10.1038/s41598-020-57670-y

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Simon, Dagmar; Simon, Hans-Uwe (2020). Relationship of skin barrier breakdown and eosinophilic esophagitis. Journal of allergy and clinical immunology, 145(1), 90-92.e1. Elsevier 10.1016/j.jaci.2019.11.005

Markov, Nikita; Simon, Hans-Uwe (2020). IL-37: A new player in the chronic rhinosinusitis arena. The Journal of allergy and clinical immunology, 145(1), pp. 105-107. Elsevier 10.1016/j.jaci.2019.10.018

Surmiak, Marcin; Gielicz, Anna; Stojkov, Darko; Szatanek, Rafał; Wawrzycka-Adamczyk, Katarzyna; Yousefi, Shida; Simon, Hans-Uwe; Sanak, Marek (2020). LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis. Journal of lipid research, 61(1), pp. 1-9. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M092072

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1

Karra, Laila; Gangwar, Roopesh Singh; Puzzovio, Pier Giorgio; Fyhrquist, Nanna; Minai-Fleminger, Yael; Landolina, Nadine; Simon, Hans-Uwe; Alenius, Harri; Leibovici, Vera; Simon, Dagmar; Levi-Schaffer, Francesca (2019). CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response. Allergy, 74(7), pp. 1377-1380. Wiley 10.1111/all.13724

Bruno, Andreina; Di Sano, Caterina; Lorusso, Francesco; Dino, Paola; Russo, Domenica; Ballacchino, Antonella; Gallina, Salvatore; Modica, Domenico Michele; Chiappara, Giuseppina; Simon, Hans-Uwe; Pace, Elisabetta (2019). Notch-1 decreased expression contributes to leptin receptor downregulation in nasal epithelium from allergic turbinates. Biochimica et biophysica acta - molecular basis of disease, 1865(6), pp. 1642-1650. Elsevier 10.1016/j.bbadis.2019.03.016

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Simon, Dagmar; Simon, Hans-Uwe (2019). Therapeutic strategies for eosinophilic dermatoses. Current opinion in pharmacology, 46, pp. 29-33. Elsevier 10.1016/j.coph.2019.01.002

Sokollik, Christiane; Simon, Hans-Uwe (2019). [Eosinophilic granulocytes-Physiology and pathophysiology]. Zeitschrift für Rheumatologie, 78(4), pp. 306-312. Springer-Medizin-Verlag 10.1007/s00393-018-0574-7

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Yadav, Sandeep Kumar; Stojkov, Darko; Feigelson, Sara W; Roncato, Francesco; Simon, Hans-Uwe; Yousefi, Shida; Alon, Ronen (2019). Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration. Journal of leukocyte biology, 105(4), pp. 755-766. Society for Leukocyte Biology 10.1002/JLB.3A1118-437RR

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Simon, Dagmar; Wollenberg, Andreas; Renz, Harald; Simon, Hans-Uwe (2019). Atopic Dermatitis: Collegium Internationale Allergologicum (CIA) Update 2019. International archives of allergy and immunology, 178(3), pp. 207-218. Karger 10.1159/000497383

Mortezavi, Ashkan; Salemi, Souzan; Kranzbühler, Benedikt; Gross, Oliver; Sulser, Tullio; Simon, Hans-Uwe; Eberli, Daniel (2019). Inhibition of autophagy significantly increases the antitumor effect of Abiraterone in prostate cancer. World journal of urology, 37(2), pp. 351-358. Springer-Verlag 10.1007/s00345-018-2385-5

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 1-8. Hogrefe 10.1024/1661-8157/a003250

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 469-476. Hogrefe 10.1024/1661-8157/a003222

Simon, Dagmar; Simon, Hans-Uwe (2019). The role of pharmacists (In Press). In: Brockow, Brockow; Mortz, Charlotte (eds.) Global atlas of skin allergy (pp. 276-278). European academy of allergy and clinical immunology

Eberli, Daniel; Horst, Maya; Mortezavi, Ashkan; Andersson, Karl-Erik; Gobet, Rita; Sulser, Tullio; Simon, Hans-Uwe; Salemi, Souzan (2018). Increased autophagy contributes to impaired smooth muscle function in neurogenic lower urinary tract dysfunction. Neurourology and urodynamics, 37(8), pp. 2414-2424. Wiley-Liss 10.1002/nau.23705

Miethe, Sarah; Guarino, Maria; Alhamdan, Fahd; Simon, Hans-Uwe; Renz, Harald; Dufour, Jean-François; Potaczek, Daniel P; Garn, Holger (2018). Effects of obesity on asthma: immunometabolic links. Polish archives of internal medicine, 128(7-8), pp. 469-477. Medycyna Praktyczna, Kraków, Poland 10.20452/pamw.4304

Arnold, Isabelle C; Artola-Borán, Mariela; Tallón de Lara, Paulino; Kyburz, Andreas; Taube, Christian; Ottemann, Karen; van den Broek, Maries; Yousefi, Shida; Simon, Hans-Uwe; Müller, Anne (2018). Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. Journal of experimental medicine, 215(8), pp. 2055-2072. Rockefeller University Press 10.1084/jem.20172049

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Sauser, Julien; Nutten, Sophie; de Groot, Nanda; Pecquet, Sophie; Simon, Dagmar; Simon, Hans-Uwe; Spergel, Jonathan M; Koletzko, Sibylle; Blanchard, Carine (2018). Partially Hydrolyzed Whey Infant Formula: Literature Review on Effects on Growth and the Risk of Developing Atopic Dermatitis in Infants from the General Population. International archives of allergy and immunology, 177(2), pp. 123-134. Karger 10.1159/000489861

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J; Arron, Joseph R; Bochner, Bruce S; Collins, Margaret H; Kahn, Jean-Emmanuel; Fulkerson, Patricia C; Gleich, Gerald J; Gopal-Srivastava, Rashmi; Jacobsen, Elizabeth A; Leiferman, Kristen M; Francesca, Levi-Schaffer; Mathur, Sameer K; Minnicozzi, Michael; Prussin, Calman; Rothenberg, Marc E; Roufosse, Florence; Sable, Kathleen; Simon, Dagmar; ... (2018). Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of leukocyte biology, 104(1), pp. 69-83. Society for Leukocyte Biology 10.1002/JLB.5MR0118-028R

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Gevaert, Elien; Yousefi, Shida; Bachert, Claus; Simon, Hans-Uwe (2018). Reply. The Journal of allergy and clinical immunology, 141(3), pp. 1164-1165. Elsevier 10.1016/j.jaci.2017.05.048

Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493

Simon, Hans-Uwe; Bieber, Thomas (2018). Allergy - Committed to Progress in Allergy and Immunology. Allergy, 73(3), p. 527. Wiley-Blackwell 10.1111/all.13412

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V; Arama, Eli; Baehrecke, Eric H; Barlev, Nickolai A; Bazan, Nicolas G; Bernassola, Francesca; Bertrand, Mathieu J M; Bianchi, Katiuscia; Blagosklonny, Mikhail V; ... (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell death and differentiation, 25(3), pp. 486-541. Nature Publishing Group 10.1038/s41418-017-0012-4

Wang, Xiaoliang; Yousefi, Shida; Simon, Hans-Uwe (2018). Necroptosis and neutrophil-associated disorders. Cell death & disease, 9(2), p. 111. Nature Publishing Group 10.1038/s41419-017-0058-8

Simon, Hans-Uwe (2018). International Archives of Allergy and Immunology: A Commitment to Serving the Community Worldwide. International archives of allergy and immunology, 175(1-2), pp. 3-4. Karger 10.1159/000485942

Simon, Dagmar; Page, Basile; Vogel, Monique; Bussmann, Christian; Blanchard, Carine; Straumann, Alex; Simon, Hans-Uwe (2018). Evidence of an abnormal epithelial barrier in active, untreated and corticosteroid-treated eosinophilic esophagitis. Allergy, 73(1), pp. 239-247. Wiley-Blackwell 10.1111/all.13244

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.

Liu, He; He, Zhaoyue; Bode, Peter; Moch, Holger; Simon, Hans-Uwe (2018). Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Frontiers in oncology, 8(366), p. 366. Frontiers Research Foundation 10.3389/fonc.2018.00366

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416

Wahn, Ulrich; Matricardi, Paolo M; Bieber, Thomas; Bousquet, Jean; Grattan, Clive; Simon, Hans-Uwe; Muraro, Antonella; Agache, Ioana (2017). Food allergy in EAACI journals (2016). Pediatric allergy and immunology, 28(8), pp. 825-830. Wiley-Blackwell 10.1111/pai.12830

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

Sokollik, Christiane; Simon, Hans-Uwe (2017). Physiologie der eosinophilen Granulozyten. Therapeutische Umschau, 74(6), pp. 291-296. Hogrefe 10.1024/0040-5930/a000917

Galluzzi, Lorenzo; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cecconi, Francesco; Choi, Augustine M; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Debnath, Jayanta; Deretic, Vojo; Dikic, Ivan; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Fulda, Simone; Gewirtz, David A; Green, Douglas R; Hansen, Malene; ... (2017). Molecular definitions of autophagy and related processes. The EMBO Journal, 36(13), pp. 1811-1836. EMBO Press 10.15252/embj.201796697

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Muraro, Antonella; Lemanske, Robert F; Castells, Mariana; Torres, Maria J; Khan, David; Simon, Hans-Uwe; Bindslev-Jensen, Carsten; Burks, Wesley; Poulsen, Lars K; Sampson, Hugh A; Worm, Margitta; Nadeau, Kari C (2017). Precision Medicine in Allergic Disease - Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Allergy, 72(7), pp. 1006-1021. Wiley-Blackwell 10.1111/all.13132

Vicari, Alain P; Schoepfer, Alain M; Meresse, Bertrand; Goffin, Laurence; Léger, Olivier; Josserand, Soheila; Guégan, Nicolas; Yousefi, Shida; Straumann, Alex; Cerf-Bensussan, Nadine; Simon, Hans-Uwe; Chvatchko, Yolande (2017). Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. mAbs, 9(6), pp. 927-944. Taylor & Francis 10.1080/19420862.2017.1332553

Gevaert, Elien; Zhang, Nan; Krysko, Olga; Lan, Feng; Holtappels, Gabriële; De Ruyck, Natalie; Nauwynck, Hans; Yousefi, Shida; Simon, Hans-Uwe; Bachert, Claus (2017). Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in severe airway inflammation. The Journal of allergy and clinical immunology, 139(6), 1849-1860.e6. Elsevier 10.1016/j.jaci.2017.01.019

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

Mortezavi, Ashkan; Salemi, Souzan; Rupp, Niels J; Rüschoff, Jan Hendrik; Hermanns, Thomas; Poyet, Cedric; Randazzo, Marco; Simon, Hans-Uwe; Moch, Holger; Sulser, Tullio; Wild, Peter; Eberli, Daniel (2017). Negative LC3b immunoreactivity in cancer cells is an independent prognostic predictor of prostate cancer specific death. OncoTarget, 8(19), pp. 31765-31774. Impact Journals LLC 10.18632/oncotarget.15986

Simon, Hans-Uwe; Friis, Robert; Tait, Stephen W G; Ryan, Kevin M (2017). Retrograde signaling from autophagy modulates stress responses. Science signaling, 10(468) American Association for the Advancement of Science 10.1126/scisignal.aag2791

Benarafa, Charaf; Simon, Hans-Uwe (2017). Role of granule proteases in the life and death of neutrophils. Biochemical and biophysical research communications, 482(3), pp. 473-481. Academic Press 10.1016/j.bbrc.2016.11.086

Blanchard, C.; Simon, Dagmar; Schoepfer, A.; Straumann, A.; Simon, Hans-Uwe (2017). Eosinophilic esophagitis: unclear roles of IgE and eosinophils. Journal of internal medicine, 281(5), pp. 448-457. Blackwell Scientific Publications 10.1111/joim.12568

Simon, Hans-Uwe; Friis, Robert; Colombo, María I. (2017). Autophagy. In: eLS Citable reviews in the life sciences (pp. 1-10). Wiley 10.1002/9780470015902.a0021581.pub2

Bousquet, Jean; Grattan, Clive; Bieber, Thomas; Matricardi, Paolo; Simon, Hans-Uwe; Wahn, Ulrich; Muraro, Antonella; Hellings, Peter W; Agache, Ioana (2017). Prediction and prevention of allergy and asthma in EAACI journals (2016). Clinical and translational allergy, 7(46), p. 46. BioMed Central 10.1186/s13601-017-0185-4

Simon, Dagmar; Straumann, Alex; Schoepfer, Alain M; Simon, Hans-Uwe (2017). Current concepts in eosinophilic esophagitis. Allergo journal international, 26(7), pp. 258-266. Springer 10.1007/s40629-017-0037-8

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Bussmann, Christian; Schoepfer, Alain M; Safroneeva, Ekaterina; Haas, Nadine; Godat, Sébastien; Sempoux, Christine; Simon, Hans-Uwe; Straumann, Alex (2016). Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy, 48(12), pp. 1069-1075. Thieme 10.1055/s-0042-117274

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Leu, T; Rauthe, S; Wirth, C; Simon, H-U; Kunzmann, V; Hebestreit, H; Kunzmann, S; Simon, Hans-Uwe (2016). [The Lymphoid Variant of HES (L-HES) as Differential Diagnose of Severe Asthma in Childhood]. Klinische Pädiatrie, 228(06/07), pp. 319-324. Thieme 10.1055/s-0042-112593

Werfel, Thomas; Allam, Jean-Pierre; Biedermann, Tilo; Eyerich, Kilian; Gilles, Stefanie; Guttman-Yassky, Emma; Hoetzenecker, Wolfram; Knol, Edward; Simon, Hans-Uwe; Wollenberg, Andreas; Bieber, Thomas; Lauener, Roger; Schmid-Grendelmeier, Peter; Traidl-Hoffmann, Claudia; Akdis, Cezmi A (2016). Cellular and molecular immunologic mechanisms in patients with atopic dermatitis. Journal of allergy and clinical immunology, 138(2), pp. 336-349. Mosby 10.1016/j.jaci.2016.06.010

Bieber, T; Akdis, C; Lauener, R; Traidl-Hoffmann, C; Schmid-Grendelmeier, P; Schäppi, G; Allam, J-P; Apfelbacher, C; Augustin, M; Beck, L; Biedermann, T; Braun-Fahrländer, C; Chew, F T; Clavel, T; Crameri, R; Darsow, U; Deleuran, M; Dittlein, D; Duchna, H-W; Eichenfeld, L; ... (2016). Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine. Allergy, 71(5), pp. 588-592. Wiley-Blackwell 10.1111/all.12857

Muraro, Antonella; Lemanske, Robert F; Hellings, Peter W; Akdis, Cezmi A; Bieber, Thomas; Casale, Thomas B; Jutel, Marek; Ong, Peck Y; Poulsen, Lars K; Schmid-Grendelmeier, Peter; Simon, Hans-Uwe; Seys, Sven F; Agache, Ioana (2016). Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Journal of allergy and clinical immunology, 137(5), pp. 1347-1358. Mosby 10.1016/j.jaci.2016.03.010

Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879

Dhayade, Sandeep; Kaesler, Susanne; Sinnberg, Tobias; Dobrowinski, Hyazinth; Peters, Stefanie; Naumann, Ulrike; Liu, He; Hunger, Robert E.; Thunemann, Martin; Biedermann, Tilo; Schittek, Birgit; Simon, Hans-Uwe; Feil, Susanne; Feil, Robert (2016). Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth. Cell reports, 14(11), pp. 2599-2610. Cell Press 10.1016/j.celrep.2016.02.028

Simon, Dagmar; Cianferoni, A; Spergel, J M; Aceves, S; Holbreich, M