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Number of items at this level: 2018.

Abd El Hafez, Mai Moustafa Ahmed

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Adam, Luise Leonore

Dopheide, Jörn F; Gillmann, Patrick; Spirk, David; Khorrami Borozadi, Meisam; Adam, Luise; Drexel, Heinz (2022). False versus True Statin Intolerance in Patients with Peripheral Artery Disease. Journal of clinical medicine, 11(22), p. 6619. MDPI 10.3390/jcm11226619

Adams, Olivia Joan

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Human IgA binds a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.20181635

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Correction: Human IgA bind a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.2018163501152020c

Adams, Olivia Joan; von Gunten, Stephan (2018). Recent Advances in Experimental Allergy. International archives of allergy and immunology, 177(4), pp. 281-289. Karger 10.1159/000494440

Aeschlimann, Salome Johanna

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Alves, Marco

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Ambühl, Maria

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

Amini, Poorya

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Amini, Poorya (2016). Optic atrophy 1 (OPA1) is essential for NET formation and antibacterial functions in neutrophils (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, Faculty of Medicine, University of Bern)

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Amstutz, Ursula

Kueng, Nicholas; Sidler, Daniel; Banz, Vanessa; Largiadèr, Carlo R; Ng, Charlotte K Y; Amstutz, Ursula (2023). Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis. Diagnostics, 13(15) MDPI 10.3390/diagnostics13152505

Andina, Nicola

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Andreasi, Valentina

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Angelillo, Anne

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

April-Monn, Simon

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Arcaro, Alexandre

Wojtalla, Anna; Fischer, Barbara; Kotelevets, Nataliya; Mauri, Francesco A; Sobek, Jens; Rehrauer, Hubert; Wotzkow, Carlos; Tschan, Mario P; Seckl, Michael J; Zangemeister-Wittke, Uwe; Arcaro, Alexandre (2013). Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clinical cancer research, 19(1), pp. 96-105. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-1138

Marinov, Marin; Ziogas, Algirdas; Pardo, Olivier E; Tan, Liwen Terence; Dhillon, Tony; Mauri, Francesco A; Lane, Heidi A; Lemoine, Nicholas R; Zangemeister-Wittke, Uwe; Seckl, Michael J; Arcaro, Alexandre (2009). AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001. Clinical cancer research, 15(4), pp. 1277-87. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-2166

Aujesky, Drahomir

Spirk, David; Sebastian, Tim; Beer, Jürg Hans; Mazzolai, Lucia; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf Peter; Korte, Wolfgang; Kucher, Nils; Barco, Stefano (2022). Role of age, sex, and specific provoking factors on the distal versus proximal presentation of first symptomatic deep vein thrombosis: analysis of the SWIss Venous ThromboEmbolism Registry (SWIVTER). Internal and emergency medicine, 17(3), pp. 799-803. Springer 10.1007/s11739-021-02878-7

Spirk, David; Sebastian, Tim; Barco, Stefano; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Blondon, Marc; Kucher, Nils (2021). Clinical Outcomes of Incidental Venous Thromboembolism in Cancer and Noncancer Patients: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 121(5), pp. 641-649. Thieme 10.1055/s-0040-1720977

Spirk, David; Sebastian, Tim; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Mollet, Annette; Szucs, Thomas D; Kucher, Nils (2019). Venous Thromboembolism and Renal Impairment: Insights from the SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 45(8), pp. 851-858. Thieme Medical Publishers 10.1055/s-0039-1698770

Blondon, Marc; Spirk, David; Kucher, Nils; Aujesky, Drahomir; Hayoz, Daniel; Beer, Jürg H; Husmann, Marc; Frauchiger, Beat; Korte, Wolfgang; Wuillemin, Walter Alfred; Bounameaux, Henri; Righini, Marc; Nendaz, Mathieu (2018). Comparative Performance of Clinical Risk Assessment Models for Hospital-Acquired Venous Thromboembolism in Medical Patients. Thrombosis and haemostasis, 118(1), pp. 82-89. Schattauer 10.1160/TH17-06-0403

Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086

Spirk, David; Stuck, Anna K.; Hager, A; Engelberger, Rolf P.; Aujesky, Drahomir; Kucher, Nils (2017). Electronic alert system for improving appropriate thromboprophylaxis in hospitalized medical patients: a randomized controlled trial. Journal of thrombosis and haemostasis, 15(11), pp. 2138-2146. Wiley-Blackwell 10.1111/jth.13812

Spirk, David; Aujesky, Drahomir; Stuck, Anna K; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Kucher, Nils (2016). Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 42(6), pp. 642-649. Thieme Medical Publishers 10.1055/s-0036-1584131

Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Spirk, David (2016). Rivaroxaban for the treatment of venous thromboembolism. The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 116(3), pp. 472-479. Schattauer 10.1160/TH16-03-0209

Spirk, David; Nendaz, M; Aujesky, Drahomir; Hayoz, D; Beer, J H; Husmann, M; Frauchiger, B; Korte, W; Wuillemin, Walter Alfred; Righini, M; Bounameaux, H; Kucher, Nils (2015). Predictors of thromboprophylaxis in hospitalised medical patients. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE). Thrombosis and haemostasis, 113(5), pp. 1127-1134. Schattauer 10.1160/TH14-06-0525

Bachmann, Daniel

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116

Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008

Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Bachmann, Martin

Plattner, Kevin; Sousa Augusto, Gilles; Muerner, Lukas; von Gunten, Stephan; Jörg, Lukas; Engeroff, Paul; Bachmann, Martin F; Vogel, Monique (2023). IgE glycosylation is essential for the function of omalizumab. Allergy, 78(9), pp. 2546-2549. Wiley 10.1111/all.15748

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Simon, Hans-Uwe; Karaulov, Alexander V; Bachmann, Martin F. (2020). Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection. International archives of allergy and immunology, 181(8), pp. 624-628. Karger 10.1159/000509368

Badmann, Anastasia

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3(12), e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2(6), e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Baerlocher, Gabriela M.

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Baltensperger, Kurt

Reinhardt, Didier; Pesce, Eva-Rachele; Stieger, Pia; Mandel, Therese; Baltensperger, Kurt; Bennett, Malcolm; Traas, Jan; Friml, Jiří; Kuhlemeier, Cris (2003). Regulation of phyllotaxis by polar auxin transport. Nature, 426(6964), pp. 255-260. Macmillan Journals Ltd. 10.1038/nature02081

Banz Wüthrich, Vanessa

Kueng, Nicholas; Sidler, Daniel; Banz, Vanessa; Largiadèr, Carlo R; Ng, Charlotte K Y; Amstutz, Ursula (2023). Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis. Diagnostics, 13(15) MDPI 10.3390/diagnostics13152505

Barut, Güliz Tuba

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Basaco Bernabeu, Tais

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Baumann, Christa Katharina

Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692

Baumgartner, Iris

Sebastian, Tim; Barco, Stefano; Engelberger, Rolf P; Spirk, David; Schindewolf, Marc; Baumann, Frederic; Baumgartner, Iris; Kucher, Nils (2020). Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. European journal of vascular and endovascular surgery EJVES, 60(3), pp. 443-450. Elsevier 10.1016/j.ejvs.2020.05.011

Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086

Engelberger, Rolf P.; Stuck, Anna; Spirk, David; Willenberg, Torsten; Haine, Axel; Périard, Daniel; Baumgartner, Iris; Kucher, Nils (2017). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute ilio-femoral deep vein thrombosis: one-year follow-up data of a randomized-controlled trial. Journal of thrombosis and haemostasis, 15(7), pp. 1351-1360. Wiley-Blackwell 10.1111/jth.13709

Spirk, David; Aujesky, Drahomir; Stuck, Anna K; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Kucher, Nils (2016). Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 42(6), pp. 642-649. Thieme Medical Publishers 10.1055/s-0036-1584131

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Silbernagel, Günther; Spirk, David; Hager, Adrian; Baumgartner, Iris; Kucher, Nils (2016). Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial. Journal of the American Heart Association, 5(7), pp. 1-7. American Heart Association 10.1161/JAHA.116.003776

Engelberger, Rolf Peter; Spirk, David; Willenberg, Torsten Andreas; Alatri, Adriano; Do, Dai-Do; Baumgartner, Iris; Kucher, Nils (2015). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Circulation: Cardiovascular interventions, 8(1) Lippincott Williams & Wilkins 10.1161/CIRCINTERVENTIONS.114.002027

Baumgartner, Johanna Maria Magdalena

Saliakoura, Maria; Rossi Sebastiano, Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Baumgartner, Stephan

Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2008). Test System Stability and Natural Variability of a Lemna Gibba L. Bioassay. PLoS ONE, 3(9), e3133. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0003133

Baumgartner, Susanne-Esther

Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2009). Effects of potentised substances on growth rate of the water plant Lemna gibba L. Complementary therapies in medicine, 17(2), pp. 63-70. Exeter: Elsevier 10.1016/j.ctim.2008.10.004

Beldi, Guido

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Beltraminelli, Helmut

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

Benarafa, Charaf

Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Burgener, Sabrina Sofia; Brügger, Melanie; Leborgne, Nathan Georges François; Sollberger, Sophia; Basilico, Paola; Kaufmann, Thomas; Bird, Phillip Ian; Benarafa, Charaf (2021). Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. Frontiers in cell and developmental biology, 9, p. 630166. Frontiers 10.3389/fcell.2021.630166

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Benarafa, Charaf; Simon, Hans-Uwe (2017). Role of granule proteases in the life and death of neutrophils. Biochemical and biophysical research communications, 482(3), pp. 473-481. Academic Press 10.1016/j.bbrc.2016.11.086

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Benjak, Andrej

Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

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Beyoğlu, Diren; Schwalm, Stephanie; Semmo, Nasser; Huwiler, Andrea; Idle, Jeffrey R (2023). Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021407

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Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

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Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

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Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

Blanchard, Olivier

Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

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Hammon, Harald M.; Bruckmaier, Rupert M.; Honegger, Ulrich E.; Blum, Jürg W. (1994). Distribution and density of α– and β–adrenergic receptor binding sites in the bovine mammary gland. Journal of dairy research, 61(1), pp. 47-57. Cambridge University Press 10.1017/S0022029900028041

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Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488

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Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

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Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2013). Glucocorticoids in autoimmune bullous diseases: are neutrophils the key cellular target? Journal of Investigative Dermatology, 133(10), pp. 2314-2315. Nature Publishing 10.1038/jid.2013.205

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Simon, D; Straumann, A; Wenk, A; Spichtin, H; Simon, H-U; Braathen, L R (2006). Eosinophilic esophagitis in adults--no clinical relevance of wheat and rye sensitizations. Allergy, 61(12), pp. 1480-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01224.x

Simon, Dagmar; Lindberg, Raija L P; Kozlowski, Evelyne; Braathen, Lasse R; Simon, Hans-Uwe (2006). Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions. Experimental dermatology, 15(6), pp. 441-6. Oxford: Blackwell 10.1111/j.0906-6705.2006.00428.x

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Brandl, Fabian; Busslinger, Sarah; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2020). Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life. Journal of controlled release, 327, pp. 186-197. Elsevier 10.1016/j.jconrel.2020.08.004

Brandl, Fabian; Merten, Hannes; Zimmermann, Martina; Béhé, Martin; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins. Journal of controlled release, 307, pp. 379-392. Elsevier 10.1016/j.jconrel.2019.06.030

Lorenzer, Cornelia; Streußnig, Sonja; Tot, Emilia; Winkler, Anna-Maria; Merten, Hannes; Brandl, Fabian; Sayers, Edward J; Watson, Peter; Jones, Arwyn T; Zangemeister-Wittke, Uwe; Plückthun, Andreas; Winkler, Johannes (2019). Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing. European journal of pharmaceutics and biopharmaceutics, 141, pp. 37-50. Elsevier 10.1016/j.ejpb.2019.05.015

Merten, Hannes; Schaefer, Jonas V; Brandl, Fabian; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Facile Site-Specific Multiconjugation Strategies in Recombinant Proteins Produced in Bacteria. Methods in molecular biology, 2033, pp. 253-273. Springer 10.1007/978-1-4939-9654-4_17

Merten, Hannes; Brandl, Fabian; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2015). Antibody-Drug Conjugates for Tumor Targeting-Novel Conjugation Chemistries and the Promise of non-IgG Binding Proteins. Bioconjugate chemistry, 26(11), pp. 2176-2185. American Chemical Society 10.1021/acs.bioconjchem.5b00260

Brigger, Daniel

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

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Britschgi, Adrian

Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Brodie, Tess Melinda

Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

Bruckmaier, Rupert

Hammon, Harald M.; Bruckmaier, Rupert M.; Honegger, Ulrich E.; Blum, Jürg W. (1994). Distribution and density of α– and β–adrenergic receptor binding sites in the bovine mammary gland. Journal of dairy research, 61(1), pp. 47-57. Cambridge University Press 10.1017/S0022029900028041

Brunner, Thomas

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3(12), e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2(6), e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Kassahn, D; Nachbur, U; Conus, S; Micheau, O; Schneider, P; Simon, H-U; Brunner, T (2009). Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell death and differentiation, 16(1), pp. 115-24. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.133

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Nachbur, Ueli; Kassahn, Daniela; Yousefi, Shida; Legler, Daniel F; Brunner, Thomas (2006). Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts. Blood, 107(7), pp. 2790-6. Washington, D.C.: American Society of Hematology 10.1182/blood-2005-07-2744

Brönnimann, Daniel

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Brügger, Melanie

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Burgener, Sabrina Sofia; Brügger, Melanie; Leborgne, Nathan Georges François; Sollberger, Sophia; Basilico, Paola; Kaufmann, Thomas; Bird, Phillip Ian; Benarafa, Charaf (2021). Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. Frontiers in cell and developmental biology, 9, p. 630166. Frontiers 10.3389/fcell.2021.630166

Bucher, Jan Rudolf

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Buri, Michelle Claudine

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Burkhalter, Sophie

Rollenske, Tim; Burkhalter, Sophie; Muerner, Lukas; von Gunten, Stephan; Lukasiewicz, Jolanta; Wardemann, Hedda; Macpherson, Andrew J. (2021). Parallelism of intestinal secretory IgA shapes functional microbial fitness. Nature, 598(7882), pp. 657-661. Springer Nature 10.1038/s41586-021-03973-7

Bär, Sarah

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2023). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. (In Press). Thrombosis and haemostasis Thieme 10.1055/a-2156-7872

Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

Bär, Sarah; Kavaliauskaite, Raminta; Otsuka, Tatsuhiko; Ueki, Yasushi; Häner, Jonas D; Siontis, George C M; Stortecky, Stefan; Shibutani, Hiroki; Temperli, Fabrice; Kaiser, Christoph; Iglesias, Juan; Jan van Geuns, Robert; Daemen, Joost; Spirk, David; Engstrøm, Thomas; Lang, Irene; Windecker, Stephan; Koskinas, Konstantinos C; Losdat, Sylvain and Räber, Lorenz (2023). Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention, 19(4), e286-e296. Europa Digital & Publishing 10.4244/EIJ-D-23-00201

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Bärlocher, Gabriela Maria

Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

Bürgi, Sibylle

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Bürgler, Christina

Bürgler, Christina; Dutoit, Danielle; Radonjic-Hoesli, Susanne; Thormann, Kathrin; Lehmann, Mathias; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2023). Dupilumab normalizes correlates of lysosomal function in atopic dermatitis (In Press). JEADV Clinical Practice Wiley 10.1002/jvc2.307

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Bürki, Kurt

Betticher, D. C.; Zucca, E.; Von Rohr, A.; Egger, T.; Radford, J. A.; Ambrosetti, A.; Bürki, K.; Rufener, B.; Hsu Schmitz, S. F.; Cerny, Thomas (1996). 2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III–IV non-Hodgkin's lymphoma. Annals of oncology, 7(8), pp. 793-799. Oxford University Press 10.1093/oxfordjournals.annonc.a010757

Bütikofer, Peter

Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356

Büttiker, Urs

Simon, Dagmar; Wittwer, Jennifer; Kostylina, Ganna; Buettiker, Urs; Simon, Hans-Uwe; Yawalkar, Nikhil (2008). Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema. Journal of allergy and clinical immunology, 122(2), pp. 423-4. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.010

Calzavarini, Sara

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Casaulta, Carmen

Peng, Shuang; Stojkov, Darko; Gao, Jian; Oberson, Kevin; Latzin, Philipp; Casaulta, Carmen; Yousefi, Shida; Simon, Hans-Uwe (2022). Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils. PLoS biology, 20(9), e3001794. Public Library of Science 10.1371/journal.pbio.3001794

Cazzaniga, Simone

Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Cerny, Thomas

Betticher, D. C.; Zucca, E.; Von Rohr, A.; Egger, T.; Radford, J. A.; Ambrosetti, A.; Bürki, K.; Rufener, B.; Hsu Schmitz, S. F.; Cerny, Thomas (1996). 2-Chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III–IV non-Hodgkin's lymphoma. Annals of oncology, 7(8), pp. 793-799. Oxford University Press 10.1093/oxfordjournals.annonc.a010757

Chan, Andrew Hao-Kuang

Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992

Chanwangpong, Apinya

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. (In Press). Clinical and translational gastroenterology Wolters Kluwer Health 10.14309/ctg.0000000000000664

Chen, Yihe

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Christen, Stephan

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Claus, Meike Janina

Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Constantinescu, Mihai Adrian

Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200

Conus, Sébastien

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

Schoepfer, Alain M; Gonsalves, Nirmala; Bussmann, Christian; Conus, Sébastien; Simon, Hans-Uwe; Straumann, Alex; Hirano, Ikuo (2010). Esophageal Dilation in Eosinophilic Esophagitis: Effectiveness, Safety, and Impact on the Underlying Inflammation. American journal of gastroenterology, 105(5), pp. 1062-1070. New York, N.Y.: Nature 10.1038/ajg.2009.657

Straumann, Alex; Conus, Sebastien; Degen, Lukas; Felder, Stephanie; Kummer, Mirjam; Engel, Hansjürg; Bussmann, Christian; Beglinger, Christoph; Schoepfer, Alain; Simon, Hans-Uwe (2010). Budesonide is effective in adolescent and adult patients with active eosinophilic esophagitis. Gastroenterology, 139(5), 1526-37, 1537.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2010.07.048

Conus, Sébastien; Straumann, Alex; Bettler, Eva; Simon, Hans-Uwe (2010). Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis. Journal of allergy and clinical immunology, 126(1), pp. 175-7. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.04.029

Straumann, A; Conus, S; Grzonka, P; Kita, H; Kephart, G; Bussmann, C; Beglinger, C; Smith, D A; Patel, J; Byrne, M; Simon, H-U (2010). Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: a randomised, placebo-controlled, double-blind trial. Gut, 59(1), pp. 21-30. London: BMJ Publishing Group 10.1136/gut.2009.178558

Conus, Sébastien; Perozzo, Remo; Reinheckel, Thomas; Peters, Christoph; Scapozza, Leonardo; Yousefi, Shida; Simon, Hans-Uwe (2008). Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. Journal of experimental medicine, 205(3), pp. 685-698. New York, N.Y.: Rockefeller University Press 10.1084/jem.20072152

Corazza, Nadia

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3(12), e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Corazza, Nadia; Kaufmann, Thomas (2012). Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models. Allergy, 67(12), pp. 1483-90. Oxford: Wiley-Blackwell 10.1111/all.12065

Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2(6), e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Courage, Carolina

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Dahinden, Clemens A.

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Simon, D.; Straumann, A.; Dahinden, C.; Simon, H.-U. (2013). Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis. Allergy, 68(7), pp. 945-948. Wiley-Blackwell 10.1111/all.12157

Daryadel, Arezoo; Yousefi, Shida; Troi, David; Schmid, Inès; Schmidt-Mende, Jan; Mordasini, Carlo; Dahinden, Clemens A; Ziemiecki, Andrew; Simon, Hans-Uwe (2009). RhoH/TTF negatively regulates leukotriene production in neutrophils. Journal of immunology, 182(10), pp. 6527-32. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803846

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Daudel, Fritz

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/jimmunol.1400028

De Brot, Simone Danielle

Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

De Marchis, Gian Marco

De Marchis, Gian Marco; Bürgi, Sibylle; Kientsch, Urs; Honegger, Ulrich E (2006). Vitamin E reduces antidepressant-related beta-adrenoceptor down-regulation in cultured cells. Comparable effects on St. John's wort and tricyclic antidepressant treatment. Planta medica, 72(15), pp. 1436-7. Stuttgart: Thieme 10.1055/s-2006-951727

Degen, Martin

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Deladoëy, Johnny

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Salemi, Souzan; Yousefi, Shida; Eblé, Andrée; Deladoëy, Johnny; Mullis, Primus E (2006). Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis. Hormone research, 65(3), pp. 132-41. Basel: Karger 10.1159/000091607

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Deng, Haibin

Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Despont, Alain

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Dewarrat, Natacha

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Di Domenico, Annunziata

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Di Santo, Stefano

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Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

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Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041396

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Federzoni, Elena

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Feldmeyer, Laurence

Radonjic-Hoesli, Susanne; Brüggen, Marie-Charlotte; Feldmeyer, Laurence; Simon, Hans-Uwe; Simon, Dagmar (2021). Eosinophils in skin diseases. Seminars in immunopathology, 43(3), pp. 393-409. Springer 10.1007/s00281-021-00868-7

Felser, Andrea Debora

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Fernández Marrero, Yuniel

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. (In Press). Clinical and translational gastroenterology Wolters Kluwer Health 10.14309/ctg.0000000000000664

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. Allergy, 77(8), pp. 2520-2533. Wiley 10.1111/all.15233

Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116

Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008

Fernandez Marrero, Yuniel; Spinner, S; Jost, P J; Kaufmann, Thomas (2016). Survival control of malignant lymphocytes by anti-apoptotic MCL-1. Leukemia, 30(11), pp. 2152-2159. Nature Publishing Group 10.1038/leu.2016.213

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Fettrelet, Timothée

Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Fettrelet, Timothée Louis

Gigon, Lea; Fettrelet, Timothée; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2023). Eosinophils from A to Z. Allergy, 78(7), pp. 1810-1846. Wiley 10.1111/all.15751

Hosseini, Aref; Stojkov, Darko; Fettrelet, Timothée; Bilyy, Rostyslav; Yousefi, Shida; Simon, Hans-Uwe (2023). Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032646

Gigon, Lea; Fettrelet, Timothée; Miholic, Marta; McLeish, Kenneth R; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2023). Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. Frontiers in immunology, 14(1272699), p. 1272699. Frontiers Research Foundation 10.3389/fimmu.2023.1272699

Fey, Martin

Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200

Britschgi, Adrian; Simon, Hans-Uwe; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2010). Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2. British journal of haematology, 149(1), pp. 55-64. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.08040.x

Andina, N; Conus, S; Schneider, E M; Fey, M F; Simon, H U (2009). Induction of Bim limits cytokine-mediated prolonged survival of neutrophils. Cell death and differentiation, 16(9), pp. 1248-55. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.50

Kuhn, A; Leupin, N; Fey, M.F.; Yousefi, S; Simon, H.U. (2008). Leukaemia cell lines are robust in vitro models - response to MacLeod & Drexler. British journal of haematology(142), pp. 138-141. Oxford: Wiley-Blackwell

Rizzi, Mattia; Tschan, Mario P; Britschgi, Christian; Britschgi, Adrian; Hügli, Barbara; Grob, Tobias J; Leupin, Nicolas; Mueller, Beatrice U; Simon, Hans-Uwe; Ziemiecki, Andrew; Torbett, Bruce E; Fey, Martin F; Tobler, Andreas (2007). The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Journal of leukocyte biology, 81(6), pp. 1599-608. Bethesda, Md.: Society for Leukocyte Biology 10.1189/jlb.0606400

Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692

Altznauer, Frank; Martinelli, Sibylla; Yousefi, Shida; Thürig, Christine; Schmid, Inès; Conway, Edward M; Schöni, Martin H; Vogt, Peter; Mueller, Christoph; Fey, Martin F; Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2004). Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils. The Journal of experimental medicine, 199(10), pp. 1343-1354. Rockefeller Univ. Press 10.1084/jem.20032033

Fiedler, Georg Martin

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Filipenko, Iuliia

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Filipenko, Iuliia; Huwiler, Andrea (2016). The role of the S1P3 receptor in inflammation-associated proliferative disorders (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Huwiler, Andrea; Feuerherm, Astrid J; Sakem, Benjamin; Pastukhov, Oleksandr; Filipenko, Iuliia; Nguyen, Thuy; Johansen, Berit (2012). The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. British journal of pharmacology, 167(8), pp. 1691-701. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02114.x

Flück Pandey, Christa Emma

Petkovic, Vibor; Salemi, Souzan; Vassella, Erik; Karamitopoulou-Diamantis, Evanthia; Meinhardt, Udo J; Flück, Christa E; Mullis, Primus E (2007). Leydig-cell tumour in children: variable clinical presentation, diagnostic features, follow-up and genetic analysis of four cases. Hormone research, 67(2), pp. 89-95. Basel: Karger 10.1159/000096356

Besson, Amélie; Salemi, Souzan; Deladoëy, Johnny; Vuissoz, Jean-Marc; Eblé, Andrée; Bidlingmaier, Martin; Bürgi, Sibylle; Honegger, Ulrich; Flück, Christa; Mullis, Primus-Eugen (2005). Short stature caused by a biologically inactive mutant growth hormone (GH-C53S). The Journal of clinical endocrinology and metabolism, 90(5), pp. 2493-2499. The Endocrine Society 10.1210/jc.2004-1838

Frangez, Ziva

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706

Wandrer, Franziska; Frangež, Živa; Liebig, Stephanie; John, Katharina; Vondran, Florian; Wedemeyer, Heiner; Veltmann, Christian; Pfeffer, Tobias J; Shibolet, Oren; Schulze-Osthoff, Klaus; Simon, Hans-Uwe; Bantel, Heike (2020). Autophagy alleviates amiodarone-induced hepatotoxicity. Archives of toxicology, 94(10), pp. 3527-3539. Springer-Verlag 10.1007/s00204-020-02837-9

Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Freigang, Stefan Bernd

Saliakoura, Maria; Rossi Sebastiano, Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Frenk, André

Barco, Stefano; Voci, Davide; Held, Ulrike; Sebastian, Tim; Bingisser, Roland; Colucci, Giuseppe; Duerschmied, Daniel; Frenk, André; Gerber, Bernhard; Götschi, Andrea; Konstantinides, Stavros V; Mach, François; Robert-Ebadi, Helia; Rosemann, Thomas; Simon, Noemi R; Spechbach, Hervé; Spirk, David; Stortecky, Stefan; Vaisnora, Lukas; Righini, Marc; ... (2022). Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial. The Lancet. Haematology, 9(8), e585-e593. Elsevier 10.1016/S2352-3026(22)00175-2

Frias Boligan, Kayluz

Almizraq, Ruqayyah J; Frias Boligan, Kayluz; Lewis, Bonnie J B; Cen, Selena; Whetstone, Heather; Spirig, Rolf; Käsermann, Fabian; Campbell, Ian K; von Gunten, Stephan; Branch, Donald R (2023). Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis. Pharmacology, 108(2), pp. 176-187. Karger 10.1159/000528780

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Yu, Yi; Ladeiras, Diogo; Xiong, Yuyan; Frias Boligan, Kayluz; Liang, Xiujie; von Gunten, Stephan; Hunger, Robert E.; Ming, Xiu-Fen; Yang, Zhihong (2020). Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. Journal of cellular physiology, 235(12), pp. 9997-10011. Wiley 10.1002/jcp.29814

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Luetscher, Ralph N D; McKitrick, Tanya R; Gao, Chao; Mehta, Akul Y; McQuillan, Alyssa M; Kardish, Robert; Frias Boligan, Kayluz; Song, Xuezheng; Lu, Lenette; Heimburg-Molinaro, Jamie; von Gunten, Stephan; Alter, Galit; Cummings, Richard D (2020). Unique repertoire of anti-carbohydrate antibodies in individual human serum. Scientific reports, 10(1), p. 15436. Springer Nature 10.1038/s41598-020-71967-y

Boligan, Kayluz F.; Oechtering, Johanna; Keller, Christian W; Peschke, Benjamin; Rieben, Robert; Bovin, Nicolai; Kappos, Ludwig; Cummings, Richard D; Kuhle, Jens; von Gunten, Stephan; Lünemann, Jan D (2020). Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS. Neurology: Neuroimmunology and Neuroinflammation, 7(2) Wolters Kluwer Health 10.1212/NXI.0000000000000676

Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Stanczak, Michal A; Siddiqui, Shoib S; Trefny, Marcel P; Thommen, Daniela S; Frias Boligan, Kayluz; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael S; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghan; Amos, Christopher I; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E; Varki, Ajit; ... (2018). Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells. Journal of clinical investigation, 128(11), pp. 4912-4923. American Society for Clinical Investigation 10.1172/JCI120612

Frias Boligan, Kayluz; von Gunten, Stephan (2017). Innate lymphoid cells in asthma: cannabinoids on the balance. Allergy, 72(6), pp. 839-841. Wiley-Blackwell 10.1111/all.13145

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Frias Boligan, Kayluz; Mesa, Circe; Fernandez, Luis Enrique; von Gunten, Stephan (2014). Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense. Cellular and molecular life sciences, 72(7), pp. 1231-1248. Springer 10.1007/s00018-014-1799-5

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Friis, Robert

Simon, Hans-Uwe; Friis, Robert; Colombo, María I. (2017). Autophagy. In: eLS Citable reviews in the life sciences (pp. 1-10). Wiley 10.1002/9780470015902.a0021581.pub2

Simon, Hans-Uwe; Friis, Robert (2014). ATG5: a distinct role in the nucleus. Autophagy, 10(1), pp. 176-177. Landes Bioscience 10.4161/auto.26916

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Constantinou, Thecla; Baumann, Fabrizio; Lacher, Markus D; Saurer, Susanne; Friis, Robert; Dharmarajan, Arun (2008). SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation. Journal of molecular signaling, 3, p. 10. London: BioMed Central 10.1186/1750-2187-3-10

Furrer, Julien

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Fux, Michaela

Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Rohner, Lionel; Reinhart, Ramona; Hagmann, Björn; Odermatt, Andrea; Babirye, Annet; Kaufmann, Thomas; Fux, Michaela (2018). FcɛRI cross-linking and IL-3 protect human basophils from intrinsic apoptotic stress. The Journal of allergy and clinical immunology, 142(5), 1647-1650.e3. Elsevier 10.1016/j.jaci.2018.06.040

Reinhart, Ramona; Rohner, Lionel; Wicki, Simone; Fux, Michaela; Kaufmann, Thomas (2018). BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells. Cell death and differentiation, 25(1), pp. 204-216. Nature Publishing Group 10.1038/cdd.2017.154

Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, Michaela (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850

Galván Hernández, José Alberto

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Gao, Yanyun

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Gargiulo, Giuseppe

Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2023). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. (In Press). Thrombosis and haemostasis Thieme 10.1055/a-2156-7872

Ge, Huixiang

Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

Geering Truffer, Barbara

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

Geering Truffer, Barbara; Schmidt-Mende, Jan; Federzoni, Elena; Stoeckle, Christina; Simon, Hans-Uwe (2011). Protein overexpression following lentiviral infection of primary mature neutrophils is due to pseudotransduction. Journal of immunological methods, 373(1-2), pp. 209-18. Amsterdam: Elsevier 10.1016/j.jim.2011.08.024

Kok, Klaartje; Geering, Barbara; Vanhaesebroeck, Bart (2009). Regulation of phosphoinositide 3-kinase expression in health and disease. Trends in biochemical sciences, 34(3), pp. 115-27. Cambridge: Elsevier Current Trends 10.1016/j.tibs.2009.01.003

Genitsch Gratwohl, Vera

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Gerber, Markus Daniel

Démoulins, Thomas; Schulze, Kai; Ebensen, Thomas; Techakriengkrai, Navapon; Nedumpun, Teerawut; Englezou, Pavlos C; Gerber, Markus; Hlushchuk, Ruslan; Toledo, Darien; Djonov, Valentin; von Gunten, Stephan; McCullough, Kenneth C; Liniger, Matthias; Guzmán, Carlos A; Suradhat, Sanipa; Ruggli, Nicolas (2023). Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases. Nanomedicine : nanotechnology, biology, and medicine, 49(102655), p. 102655. Elsevier 10.1016/j.nano.2023.102655

Germic, Nina

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. (In Press). Clinical and translational gastroenterology Wolters Kluwer Health 10.14309/ctg.0000000000000664

Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14 Frontiers Research Foundation 10.3389/fimmu.2023.1331151

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. Allergy, 77(8), pp. 2520-2533. Wiley 10.1111/all.15233

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

Gertsch, Jürg

Saliakoura, Maria; Reynoso-Moreno, Inés; Pozzato, Chiara; Rossi Sebastiano, Matteo; Galié, Mirco; Gertsch, Jürg; Konstantinidou, Georgia (2020). The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Oncogene, 39(14), pp. 2948-2960. Springer Nature 10.1038/s41388-020-1196-5

Gigon, Lea

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Gigon, Lea; Fettrelet, Timothée; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2023). Eosinophils from A to Z. Allergy, 78(7), pp. 1810-1846. Wiley 10.1111/all.15751

Gigon, Lea; Fettrelet, Timothée; Miholic, Marta; McLeish, Kenneth R; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2023). Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. Frontiers in immunology, 14(1272699), p. 1272699. Frontiers Research Foundation 10.3389/fimmu.2023.1272699

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003

Gillmann, Patrick Theis

Dopheide, Jörn F; Gillmann, Patrick; Spirk, David; Khorrami Borozadi, Meisam; Adam, Luise; Drexel, Heinz (2022). False versus True Statin Intolerance in Patients with Peripheral Artery Disease. Journal of clinical medicine, 11(22), p. 6619. MDPI 10.3390/jcm11226619

Girousi, Eleftheria

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Gjuroski, Ilche

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Gloor, Beat

Worni, Mathias; Güller, Ulrich; White, Rebekah R.; Castleberry, Anthony W.; Pietrobon, Ricardo; Cerny, Thomas; Gloor, Beat; Köberle, Dieter (2013). Modest Improvement in Overall Survival for Patients With Metastatic Pancreatic Cancer. Pancreas, 42(7), pp. 1157-1163. Lippincott Williams & Wilkins 10.1097/MPA.0b013e318291fbc5

Gottstein, Bruno

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Graber, Werner Adrian

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Graeter, Stefanie Rebecca

Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Grafinger, Katharina

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Grafinger, Katharina Elisabeth; Liechti, Matthias E; Liakoni, Evangelia (2020). Clinical value of analytical testing in patients presenting with New Psychoactive Substances intoxication. British journal of clinical pharmacology, 86(3), pp. 429-436. Wiley-Blackwell 10.1111/bcp.14115

Grandgirard, Denis

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Guarino, Maria

Miethe, Sarah; Guarino, Maria; Alhamdan, Fahd; Simon, Hans-Uwe; Renz, Harald; Dufour, Jean-François; Potaczek, Daniel P; Garn, Holger (2018). Effects of obesity on asthma: immunometabolic links. Polish archives of internal medicine, 128(7-8), pp. 469-477. Medycyna Praktyczna, Kraków, Poland 10.20452/pamw.4304

Gurzeler, Ursina

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206

Güller, Ulrich

Worni, Mathias; Güller, Ulrich; White, Rebekah R.; Castleberry, Anthony W.; Pietrobon, Ricardo; Cerny, Thomas; Gloor, Beat; Köberle, Dieter (2013). Modest Improvement in Overall Survival for Patients With Metastatic Pancreatic Cancer. Pancreas, 42(7), pp. 1157-1163. Lippincott Williams & Wilkins 10.1097/MPA.0b013e318291fbc5

Haas, Nadine Agnès Marie-Anne

Bussmann, Christian; Schoepfer, Alain M; Safroneeva, Ekaterina; Haas, Nadine; Godat, Sébastien; Sempoux, Christine; Simon, Hans-Uwe; Straumann, Alex (2016). Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy, 48(12), pp. 1069-1075. Thieme 10.1055/s-0042-117274

Haas, Quentin

Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Hugonnet, Marjolaine; Singh, Pushpita; Haas, Quentin; von Gunten, Stephan (2021). The Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology. Frontiers in immunology, 12, p. 799861. Frontiers Research Foundation 10.3389/fimmu.2021.799861

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Hall, Sean

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Hammann, Felix

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Haschke, Manuel Martin

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Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488

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Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

He, Zhaoyue

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

He, Zhaoyue; Liu, He; Moch, Holger; Simon, Hans-Uwe (2020). Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Scientific reports, 10(1), p. 720. Springer Nature 10.1038/s41598-020-57670-y

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Liu, He; He, Zhaoyue; Bode, Peter; Moch, Holger; Simon, Hans-Uwe (2018). Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Frontiers in oncology, 8(366), p. 366. Frontiers Research Foundation 10.3389/fonc.2018.00366

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2016). The Role of Autophagy in Cancer and Chemotherapy. In: Hayat, M. (ed.) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Human Diseases: Vol. 8 (pp. 253-265). Academic Press 10.1016/B978-0-12-802937-4.00014-4

He, Zhaoyue; Agostini, Massimiliano; Liu, He; Melino, Gerry; Simon, Hans-Uwe (2015). p73 regulates basal and starvation-induced liver metabolism in vivo. OncoTarget, 6(32), pp. 33178-33190. Impact Journals LLC 10.18632/oncotarget.5090

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2015). Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. Journal of molecular medicine JMM, 93(2), pp. 159-164. Springer 10.1007/s00109-014-1241-3

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2014). Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy, 10(2), pp. 372-373. Landes Bioscience 10.4161/auto.27163

He, Z.; Simon, H. U. (2013). Autophagy protects from liver injury. Cell death and differentiation, 20(7), pp. 850-851. Nature Publishing Group 10.1038/cdd.2013.43

He, Zhaoyue; Simon, Hans-Uwe (2013). A novel link between p53 and ROS. Cell Cyle, 12(2), pp. 201-202. Landes Bioscience 10.4161/cc.23418

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2013). Targeting autophagy as a potential therapeutic approach for melanoma therapy. Seminars in Cancer Biology, 5(23), pp. 352-360. Elsevier 10.1016/j.semcancer.2013.06.008

Heg, Dierik Hans

Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

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Heidemeyer, Kristine

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Helbling, Arthur

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Heller, Manfred

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

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Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Herzog, Elio Luca

Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

Heussler, Volker

Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia; ... (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. Taylor & Francis 10.1080/15548627.2020.1797280

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von Achenbach, Caroline; Hevia Hernandez, Giselle; von Gunten, Stephan (2022). The Choice between Intravenous and Subcutaneous Immunoglobulins: Aspects for Consideration. Pharmacology, 107(11-12), pp. 556-563. Karger 10.1159/000527655

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Démoulins, Thomas; Schulze, Kai; Ebensen, Thomas; Techakriengkrai, Navapon; Nedumpun, Teerawut; Englezou, Pavlos C; Gerber, Markus; Hlushchuk, Ruslan; Toledo, Darien; Djonov, Valentin; von Gunten, Stephan; McCullough, Kenneth C; Liniger, Matthias; Guzmán, Carlos A; Suradhat, Sanipa; Ruggli, Nicolas (2023). Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases. Nanomedicine : nanotechnology, biology, and medicine, 49(102655), p. 102655. Elsevier 10.1016/j.nano.2023.102655

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Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/jimmunol.1400028

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Hofstetter-Jenny, Willy

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Horn, Michael

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Horn, Michael Peter

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Hosseini, Aref

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. (In Press). Clinical and translational gastroenterology Wolters Kluwer Health 10.14309/ctg.0000000000000664

Hosseini, Aref; Stojkov, Darko; Fettrelet, Timothée; Bilyy, Rostyslav; Yousefi, Shida; Simon, Hans-Uwe (2023). Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032646

Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14 Frontiers Research Foundation 10.3389/fimmu.2023.1331151

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. Allergy, 77(8), pp. 2520-2533. Wiley 10.1111/all.15233

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

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Huwiler, Andrea; Beck, Karl-Friedrich; Pfeilschifter, Josef (2023). Cross-Regulation of the Cellular Redox System, Oxygen, and Sphingolipid Signalling. Metabolites, 13(3) MDPI 10.3390/metabo13030426

Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Pavenstädt, Hermann; Pfeilschifter, Josef; Huwiler, Andrea (2023). Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043267

Stepanovska Tanturovska, Bisera; Manaila, Roxana; Fabbro, Doriano; Huwiler, Andrea (2023). Lipids as Targets for Renal Cell Carcinoma Therapy. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043272

Beyoğlu, Diren; Schwalm, Stephanie; Semmo, Nasser; Huwiler, Andrea; Idle, Jeffrey R (2023). Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021407

Hafizi, Redona; Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Schwalm, Stephanie; Trautmann, Sandra; Wenger, Roland H; Pfeilschifter, Josef; Huwiler, Andrea (2022). Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells. International journal of molecular sciences, 23(11) MDPI 10.3390/ijms23115882

Theodoropoulou, Maria A; Psarra, Anastasia; Erhardt, Martin; Nikolaou, Aikaterini; Gerogiannopoulou, Anna-Dimitra D; Hadjipavlou-Litina, Dimitra; Hayashi, Daiki; Dennis, Edward A; Huwiler, Andrea; Kokotos, George (2022). N-Acylated and N-Alkylated 2-Aminobenzothiazoles Are Novel Agents That Suppress the Generation of Prostaglandin E2. Biomolecules, 12(2) MDPI 10.3390/biom12020267

Hafizi, Redona; Imeri, Faik; Wenger, Roland H.; Huwiler, Andrea (2021). S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization. International journal of molecular sciences, 22(17) MDPI 10.3390/ijms22179467

Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Imeri, Faik; Homann, Thomas; Kleuser, Burkhard; Stark, Holger; Huwiler, Andrea (2021). ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo. Molecules, 26(17) Molecular Diversity Preservation International MDPI 10.3390/molecules26175134

Huwiler, Andrea; Pfeilschifter, Josef (2021). Recuperation of Vascular Homeostasis. Circulation research, 129(2), pp. 237-239. American Heart Association 10.1161/CIRCRESAHA.121.319558

Imeri, Faik; Stepanovska Tanturovska, Bisera; Schwalm, Stephanie; Saha, Sarbari; Zeng-Brouwers, Jinyang; Pavenstädt, Herrmann; Pfeilschifter, Josef; Schaefer, Liliana; Huwiler, Andrea (2021). Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice. Matrix biology, 98, pp. 32-48. Elsevier 10.1016/j.matbio.2021.05.003

Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Schwalm, Stephanie; Beyer, Sandra; Hafizi, Redona; Trautmann, Sandra; Geisslinger, Gerd; Adams, David R; Pyne, Susan; Pyne, Nigel; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2021). Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis. Cellular signalling, 79(109881), p. 109881. Elsevier 10.1016/j.cellsig.2020.109881

Psarra, Anastasia; Theodoropoulou, Maria A; Erhardt, Martin; Mertiri, Marina; Mantzourani, Christiana; Vasilakaki, Sofia; Magrioti, Victoria; Huwiler, Andrea; Kokotos, George (2021). α-Ketoheterocycles Able to Inhibit the Generation of Prostaglandin E2 (PGE2) in Rat Mesangial Cells. Biomolecules, 11(2) MDPI 10.3390/biom11020275

Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2020). Corrigendum to "Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms" [Biochim. Biophys. Acta Mol. Basis Dis. 2019 Apr 1;1865(4):774-781]. Biochimica et biophysica acta - molecular basis of disease, 1866(10), p. 165892. Elsevier 10.1016/j.bbadis.2020.165892

Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463

Stepanovska, Bisera; Huwiler, Andrea (2020). Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases. Pharmacological research, 154, p. 104170. Elsevier 10.1016/j.phrs.2019.02.009

Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041396

Stepanovska, Bisera; Lange, Antonia I; Schwalm, Stephanie; Pfeilschifter, Josef; Coldewey, Sina M; Huwiler, Andrea (2020). Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041240

Dennhardt, Sophie; Finke, Karl R; Huwiler, Andrea; Coldewey, Sina M (2019). Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms. Biochimica et biophysica acta - molecular basis of disease, 1865(4), pp. 774-781. Elsevier 10.1016/j.bbadis.2018.12.022

Evangelopoulos, Maria Eleftheria; Miclea, Andrei; Schrewe, Lisa; Briner, Myriam; Salmen, Anke; Engelhardt, Britta; Huwiler, Andrea; Chan, Andrew; Hoepner, Robert (2018). Frequency and clinical characteristics of Multiple Sclerosis rebounds after withdrawal of Fingolimod. CNS neuroscience & therapeutics, 24(10), pp. 984-986. Wiley 10.1111/cns.12992

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Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

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Vasilakaki, Sofia; Pastukhov, Oleksandr; Mavromoustakos, Thomas; Huwiler, Andrea; Kokotos, George (2018). Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells. Molecules, 23(1) Molecular Diversity Preservation International MDPI 10.3390/molecules23010158

Beyer, Sandra; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2018). Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. Cellular physiology and biochemistry, 47(6), pp. 2522-2533. Karger 10.1159/000491625

Schwalm, Stephanie; Beyer, Sandra; Frey, Helena; Haceni, Riad; Grammatikos, Georgios; Thomas, Dominique; Geisslinger, Gerd; Schaefer, Liliana; Huwiler, Andrea; Pfeilschifter, Josef (2017). Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction. American journal of pathology, 187(11), pp. 2413-2429. Elsevier 10.1016/j.ajpath.2017.06.017

Hsieh, Louise Tzung-Harn; Nastase, Madalina-Viviana; Roedig, Heiko; Zeng-Brouwers, Jinyang; Poluzzi, Chiara; Schwalm, Stephanie; Fork, Christian; Tredup, Claudia; Brandes, Ralf P; Wygrecka, Malgorzata; Huwiler, Andrea; Pfeilschifter, Josef; Schaefer, Liliana (2017). Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants. International journal of molecular sciences, 18(3) Molecular Diversity Preservation International MDPI 10.3390/ijms18030595

McCracken, A N; McMonigle, R J; Tessier, J; Fransson, R; Perryman, M S; Chen, B; Keebaugh, A; Selwan, E; Barr, S A; Kim, S M; Roy, S G; Liu, G; Fallegger, D; Sernissi, L; Brandt, C; Moitessier, N; Snider, A J; Clare, S; Müschen, M; Huwiler, Andrea; ... (2017). Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation. Leukemia, 31(3), pp. 669-677. Nature Publishing Group 10.1038/leu.2016.244

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Vasilakaki, Sofia; Barbayianni, Efrosini; Magrioti, Victoria; Pastukhov, Oleksandr; Constantinou-Kokotou, Violetta; Huwiler, Andrea; Kokotos, George (2016). Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells. Bioorganic & medicinal chemistry, 24(13), pp. 3029-3034. Elsevier 10.1016/j.bmc.2016.05.017

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Chen, Bin; Roy, Saurabh G; McMonigle, Ryan J; Keebaugh, Andrew; McCracken, Alison N; Selwan, Elizabeth; Fransson, Rebecca; Fallegger, Daniel; Huwiler, Andrea; Kleinman, Michael T; Edinger, Aimee L; Hanessian, Stephen (2016). Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo. ACS Chemical Biology, 11(2), pp. 409-414. American Chemical Society 10.1021/acschembio.5b00761

Coldewey, Sina M; Benetti, Elisa; Collino, Massimo; Pfeilschifter, Josef; Sponholz, Christoph; Bauer, Michael; Huwiler, Andrea; Thiemermann, Christoph (2016). Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis. Scientific Reports, 6, p. 27594. Nature Publishing Group 10.1038/srep27594

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Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

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Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Schröder, Matthias; Arlt, Olga; Schmidt, Helmut; Huwiler, Andrea; Angioni, Carlo; Pfeilschifter, Josef M; Schwiebs, Anja; Radeke, Heinfried H (2015). Subcellular distribution of FTY720 and FTY720-phosphate in immune cells - another aspect of Fingolimod action relevant for therapeutic application. Biological chemistry, 396(6-7), pp. 795-802. De Gruyter 10.1515/hsz-2014-0287

Wünsche, Christin; Koch, Alexander; Goldschmeding, Roel; Schwalm, Stephanie; Meyer Zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2015). Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1851(5), pp. 519-526. Elsevier 10.1016/j.bbalip.2015.01.003

Koch, Alexander; Jäger, Manuel; Völzke, Anja; Grammatikos, Georgios; Zu Heringdorf, Dagmar Meyer; Huwiler, Andrea; Pfeilschifter, Josef (2015). Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration. Biological chemistry, 396(6-7), pp. 803-812. De Gruyter 10.1515/hsz-2014-0288

Pastukhov, Oleksandr; Schalm, Stephanie; Zangemeister-Wittke, Uwe; Fabbro, Doriano; Bornancin, Frederic; Japtok, Lukasz; Kleuser, Burkhrad; Pfeilschifter, Josef; Huwiler, Andrea (2014). The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death. British journal of pharmacology, 171(24), pp. 5829-5844. Wiley-Blackwell 10.1111/bph.12886

Imeri, Faik; Fallegger, Daniel; Zivkovic, Aleksandra; Schwalm, Stephanie; Enzmann, Gaby; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Homann, Thomas; Kleuser, Burkhard; Pfeilschifter, Josef; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2014). Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology, 85, pp. 314-327. Elsevier 10.1016/j.neuropharm.2014.05.012

Thangaiyan, Rabi; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells. Molecular carcinogenesis, 53(7), pp. 578-588. Wiley 10.1002/mc.22012

Imeri, Faik; Jashri, Ahmed; Bullazhi, Lulzime; Shabani, Agim; Mikhova, Bozhana; Dräger, Gerald; Popovski, Emil; Huwiler, Andrea (2014). Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death. Bioorganic & medicinal chemistry, 22(9), pp. 2655-2660. Elsevier 10.1016/j.bmc.2014.03.026

Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2014). Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. Basic & clinical pharmacology & toxicology, 1(114), pp. 44-49. Wiley-Blackwell 10.1111/bcpt.12103

Völzke, Anja; Koch, Alexander; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2014). Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1841(1), pp. 11-21. Elsevier 10.1016/j.bbalip.2013.09.009

Kondo, Shunya; Bottos, Alessia; Allegood, Jeremy C.; Masson, Regis; Maurer, Francisca G.; Genoud, Christel; Kaeser, Patrick; Huwiler, Andrea; Murakami, Masato; Spiegel, Sarah; Hynes, Nancy E. (2014). Memo has a novel role in S1P signaling and crucial for vascular development. PLoS ONE, 9(4), e94114. Public Library of Science 10.1371/journal.pone.0094114

Pastukhov, Oleksandr; Schalm, Stephanie; Römer, Isolde; Pfeilschifter, Josef; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts. Cellular physiology and biochemistry, 34(1), pp. 119-133. Karger 10.1159/000362989

Bhabak, Krishna P.; Kleuser, Burkhard; Huwiler, Andrea; Arenz, Christoph (2013). Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues. Bioorganic & medicinal chemistry, 21(4), pp. 874-882. Elsevier 10.1016/j.bmc.2012.12.014

Koch, Alexander; Völzke, Anja; Puff, Bianca; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2013). PARγ agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca(2+)]i increases in renal mesangial cells. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(11), pp. 1634-1643. Elsevier 10.1016/j.bbalip.2013.07.011

Albinet, V.; Bats, M-L; Huwiler, Andrea; Rochaix, P.; Chevreau, C.; Ségui, B.; Levande, T.; Andrieu-Abadie, N. (2013). Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells. Oncogene, 33(26), pp. 3364-3373. Nature Publishing Group 10.1038/onc.2013.303

Schwlam, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2013). Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases. Biochimica and biophysica acta - molecular and cell biology of lipids, 1831(1), pp. 239-250. Elsevier 10.1016/j.bbalip.2012.07.022

Koch, Alexander; Pfeilschrifter, Josef; Huwiler, Andrea (2013). Sphingosine 1-phosphate in renal diseases. Cellular physiology and biochemistry, 31(6), pp. 745-760. Karger 10.1159/000350093

Huwiler, Andrea; Feuerherm, Astrid J; Sakem, Benjamin; Pastukhov, Oleksandr; Filipenko, Iuliia; Nguyen, Thuy; Johansen, Berit (2012). The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. British journal of pharmacology, 167(8), pp. 1691-701. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02114.x

Kotelevets, Nataliya; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2012). Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. PLoS ONE, 7(6), e39209. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0039209

Koch, A; Völzke, A; Wünsche, C; Meyer zu Heringdorf, D; Huwiler, A; Pfeilschifter, J (2012). Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells. British journal of pharmacology, 166(3), pp. 1018-32. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.01824.x

Ter Braak, Michael; Claas, Ralf Frederik; Hegen, Bianca; Labocha, Sandra; Ferreirós, Nerea; Pfeilschifter, Josef; Huwiler, Andrea; van Echten-Deckert, Gerhild; Meyer Zu Heringdorf, Dagmar (2011). Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator. Biochemical pharmacology, 81(5), pp. 617-25. New York, N.Y.: Elsevier 10.1016/j.bcp.2010.12.002

Pfeilschifter, Waltraud; Czech-Zechmeister, Bo?ena; Sujak, Marian; Mirceska, Ana; Koch, Alexander; Rami, Abdelhaq; Steinmetz, Helmuth; Foerch, Christian; Huwiler, Andrea; Pfeilschifter, Josef (2011). Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia. Biochemical and biophysical research communications, 413(2), pp. 212-7. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2011.08.070

Huwiler, Andrea; Bourquin, Florence; Kotelevets, Nataliya; Pastukhov, Oleksandr; Capitani, Guido; Grütter, Markus G; Zangemeister-Wittke, Uwe (2011). A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders. PLoS ONE, 6(8), e22436. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022436

Schröder, Matthias; Richter, Cornelia; Juan, Martina Herrero San; Maltusch, Katrin; Giegold, Oliver; Quintini, Gianluca; Pfeilschifter, Josef M; Huwiler, Andrea; Radeke, Heinfried H (2011). The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen. Molecular immunology, 48(9-10), pp. 1139-48. Amsterdam: Elsevier 10.1016/j.molimm.2011.02.007

Huwiler, Andrea; Kotelevets, Nataliya; Xin, Cuiyan; Pastukhov, Oleksandr; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe (2011). Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage. British journal of pharmacology, 162(2), pp. 532-43. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.01053.x

Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2010). Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation. British journal of pharmacology, 160(7), pp. 1641-51. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.00818.x

Puneet, Padmam; Yap, Celestial T; Wong, Lingkai; Lam, Yulin; Koh, Dow Rhoon; Moochhala, Shabbir; Pfeilschifter, Josef; Huwiler, Andrea; Melendez, Alirio J (2010). SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis. Science, 328(5983), pp. 1290-4. Washington, D.C.: American Association for the Advancement of Science 10.1126/science.1188635

Ren, Shuyu; Xin, Cuiyan; Pfeilschifter, Josef; Huwiler, Andrea (2010). A novel mode of action of the putative sphingosine kinase inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole (SKI II): induction of lysosomal sphingosine kinase 1 degradation. Cellular physiology and biochemistry, 26(1), pp. 97-104. Basel: Karger 10.1159/000315110

Förster, Ankathrin; Emmler, Tanja; Schwalm, Stephanie; Ebadi, Mahsa; Heringdorf, Dagmar Meyer Zu; Nieuwenhuis, Barbara; Kleuser, Burkhardt; Huwiler, Andrea; Pfeilschifter, Josef (2010). Glucocorticoids protect renal mesangial cells from apoptosis by increasing cellular sphingosine-1-phosphate. Kidney international, 77(10), pp. 870-9. New York, N.Y.: Nature Publishing Group 10.1038/ki.2010.62

Czech, Bozena; Pfeilschifter, Waltraud; Mazaheri-Omrani, Niloufar; Strobel, Marc André; Kahles, Timo; Neumann-Haefelin, Tobias; Rami, Abdelhaq; Huwiler, Andrea; Pfeilschifter, Josef (2009). The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. Biochemical and biophysical research communications, 389(2), pp. 251-6. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2009.08.142

Ren, Shuyu; Babelova, Andrea; Moreth, Kristin; Xin, Cuiyan; Eberhardt, Wolfgang; Doller, Anke; Pavenstädt, Hermann; Schaefer, Liliana; Pfeilschifter, Josef; Huwiler, Andrea (2009). Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. Kidney international, 76(8), pp. 857-67. New York, N.Y.: Nature Publishing Group 10.1038/ki.2009.297

Huwiler, Andrea; Pfeilschifter, Josef (2009). Lipids as targets for novel anti-inflammatory therapies. Pharmacology & therapeutics, 124(1), pp. 96-112. Amsterdam: Elsevier 10.1016/j.pharmthera.2009.06.008

Pushparaj, Peter N; Manikandan, Jayapal; Tay, Hwee Kee; H'ng, Shiau Chen; Kumar, Srinivasan D; Pfeilschifter, Josef; Huwiler, Andrea; Melendez, Alirio J (2009). Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo. Journal of immunology, 183(1), pp. 221-7. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803430

Nieuwenhuis, Barbara; Lüth, Anja; Chun, Jerold; Huwiler, Andrea; Pfeilschifter, Josef; Schäfer-Korting, Monika; Kleuser, Burkhard (2009). Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P(3) in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone. International journal of molecular medicine, 87(6), pp. 645-57. Athens: Spandidos Publications 10.1007/s00109-009-0468-x

Huwiler, A; Pfeilschifter, J (2009). Lipid signalling - Ample opportunitites for novel drug targets. BioForum Europe, 10/200, pp. 22-23. Darmstadt: GIT-Verlag

Hofmann, Lotte P; Ren, Shuyu; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2008). Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner. Biological chemistry, 389(11), pp. 1399-407. Berlin: Walter de Gruyter 10.1515/BC.2008.160

Huwiler, Andrea; Pfeilschifter, Josef (2008). New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets. Biochemical pharmacology, 75(10), pp. 1893-900. New York, N.Y.: Elsevier 10.1016/j.bcp.2007.12.018

Schwalm, Stephanie; Döll, Frauke; Römer, Isolde; Bubnova, Svetlana; Pfeilschifter, Josef; Huwiler, Andrea (2008). Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells. Biochemical and biophysical research communications, 368(4), pp. 1020-5. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2008.01.132

Schade-Kampmann, G; Huwiler, A; Hebeisen, M; Hessler, T; Di Berardino, M (2008). On-chip non-invasive and label-free cell discrimination by impedance spectroscopy. Anaesthesia, 41(5), pp. 830-40. Oxford: Wiley-Blackwell 10.1111/j.1365-2184.2008.00548.x

Doller, Anke; Akool, El-Sayed; Huwiler, Andrea; Müller, Roswitha; Radeke, Heinfried H; Pfeilschifter, Josef; Eberhardt, Wolfgang (2008). Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA. Molecular and cellular biology, 28(8), pp. 2608-25. Washington, D.C.: American Society for Microbiology 10.1128/MCB.01530-07

Huwiler, Andrea (2008). Antiarthrotic and Immunomodulatory Activity (Check index of the book for specific contributions). In: Vogel, Hans Gerhard (ed.) Drug Discovery and Evaluation: Pharmacological Assays, Vol 1 and 2 (pp. 1117-1190). Heidelberg: Springer Verlag 10.1007/978-3-540-70995-4_10

Klawitter, S; Hofmann, L P; Pfeilschifter, J; Huwiler, A (2007). Extracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase-1 expression and activity. British journal of pharmacology, 150(3), pp. 271-80. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0706983

Huwiler, Andrea; Zangemeister-Wittke, Uwe (2007). Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. Critical reviews in oncology, hematology, 63(2), pp. 150-9. Boca Raton, Fla.: Elsevier 10.1016/j.critrevonc.2007.04.010

Döll, Frauke; Pfeilschifter, Josef; Huwiler, Andrea (2007). Prolactin upregulates sphingosine kinase-1 expression and activity in the human breast cancer cell line MCF7 and triggers enhanced proliferation and migration. Endocrine-related cancer, 14(2), pp. 325-35. Bristol: BioScientifica Ltd. 10.1677/ERC-06-0050

Xin, Cuiyan; Ren, Shuyu; Eberhardt, Wolfgang; Pfeilschifter, Josef; Huwiler, Andrea (2007). Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1beta-induced prostaglandin E2 formation. Journal of lipid research, 48(9), pp. 1985-96. Bethesda, Md.: American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M700077-JLR200

Ulrich, Sandra; Huwiler, Andrea; Loitsch, Stefan; Schmidt, Helmut; Stein, Jürgen M (2007). De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity. Biochemical pharmacology, 74(2), pp. 281-9. New York, N.Y.: Elsevier 10.1016/j.bcp.2007.04.001

Doller, Anke; Huwiler, Andrea; Müller, Roswitha; Radeke, Heinfried H; Pfeilschifter, Josef; Eberhardt, Wolfgang (2007). Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Molecular biology of the cell, 18(6), pp. 2137-48. Bethesda, Md.: American Society for Cell Biology 10.1091/mbc.E06-09-0850

Xin, C; Ren, S; Eberhardt, W; Pfeilschifter, J; Huwiler, A (2007). FTY720 suppresses interleukin-1beta-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism. British journal of pharmacology, 150(7), pp. 943-50. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0707171

Zangemeister-Wittke, Uwe; Huwiler, Andrea (2006). Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer. Cancer biology & therapy, 5(10), pp. 1355-1356. Georgetown, Tex.: Landes Bioscience 10.4161/cbt.5.10.3488

Huwiler, Andrea; Pfeilschifter, Josef (2006). Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy. Current pharmaceutical design, 12(35), pp. 4625-35. Hilversum: Bentham Science Publishers 10.2174/138161206779010422

Huwiler, Andrea; Pfeilschifter, Josef (2006). Hypoxia and lipid signaling. Biological chemistry, 387(10-11), pp. 1321-1328. Berlin: Walter de Gruyter 10.1515/BC.2006.165

Huwiler, Andrea; Döll, Frauke; Ren, Shuyu; Klawitter, Sabine; Greening, Anna; Römer, Isolde; Bubnova, Svetlana; Reinsberg, Luise; Pfeilschifter, Josef (2006). Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism. Biochimica and biophysica acta - molecular and cell biology of lipids, 1761(3), pp. 367-376. Biochimica and biophysica acta - molecular and cell biology of lipids: Elsevier 10.1016/j.bbalip.2006.02.007

Xin, Cuiyan; Ren, Shuyu; Eberhardt, Wolfgang; Pfeilschifter, Josef; Huwiler, Andrea (2006). The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells. British journal of pharmacology, 147(2), pp. 164-74. Oxford: Wiley-Blackwell 10.1038/sj.bjp.0706452

Plesková, Miriam; Beck, Karl-Friedrich; Behrens, Meik Helmut; Huwiler, Andrea; Fichtlscherer, Birgit; Wingerter, Oliver; Brandes, Ralf P; Mülsch, Alexander; Pfeilschifter, Josef (2006). Nitric oxide down-regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cells. FASEB journal, 20(1), pp. 139-41. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.05-3791fje

Häner, Jonas

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2023). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. (In Press). Thrombosis and haemostasis Thieme 10.1055/a-2156-7872

Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

Bär, Sarah; Kavaliauskaite, Raminta; Otsuka, Tatsuhiko; Ueki, Yasushi; Häner, Jonas D; Siontis, George C M; Stortecky, Stefan; Shibutani, Hiroki; Temperli, Fabrice; Kaiser, Christoph; Iglesias, Juan; Jan van Geuns, Robert; Daemen, Joost; Spirk, David; Engstrøm, Thomas; Lang, Irene; Windecker, Stephan; Koskinas, Konstantinos C; Losdat, Sylvain and Räber, Lorenz (2023). Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention, 19(4), e286-e296. Europa Digital & Publishing 10.4244/EIJ-D-23-00201

Räber, Lorenz; Ueki, Yasushi; Otsuka, Tatsuhiko; Losdat, Sylvain; Häner, Jonas D; Lonborg, Jacob; Fahrni, Gregor; Iglesias, Juan F; van Geuns, Robert-Jan; Ondracek, Anna S; Radu Juul Jensen, Maria D; Zanchin, Christian; Stortecky, Stefan; Spirk, David; Siontis, George C; Saleh, Lanja; Matter, Christian M; Daemen, Joost; Mach, François; Heg, Dik; ... (2022). Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial. JAMA - the journal of the American Medical Association, 327(18), pp. 1771-1781. American Medical Association 10.1001/jama.2022.5218

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Zanchin, Christian; Ueki, Yasushi; Losdat, Sylvain; Fahrni, Gregor; Daemen, Joost; Ondracek, Anna S; Häner, Jonas D.; Stortecky, Stefan; Otsuka, Tatsuhiko; Siontis, George C.M.; Rigamonti, Fabio; Radu, Maria; Spirk, David; Kaiser, Christoph; Engstrom, Thomas; Lang, Irene; Koskinas, Konstantinos C.; Räber, Lorenz (2021). In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study. European heart journal - cardiovascular imaging, 22(7), pp. 824-834. Oxford University Press 10.1093/ehjci/jez318

Idle, Jeffrey

Beyoğlu, Diren; Schwalm, Stephanie; Semmo, Nasser; Huwiler, Andrea; Idle, Jeffrey R (2023). Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021407

Imeri, Faik

Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Pavenstädt, Hermann; Pfeilschifter, Josef; Huwiler, Andrea (2023). Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043267

Hafizi, Redona; Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Schwalm, Stephanie; Trautmann, Sandra; Wenger, Roland H; Pfeilschifter, Josef; Huwiler, Andrea (2022). Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells. International journal of molecular sciences, 23(11) MDPI 10.3390/ijms23115882

Hafizi, Redona; Imeri, Faik; Wenger, Roland H.; Huwiler, Andrea (2021). S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization. International journal of molecular sciences, 22(17) MDPI 10.3390/ijms22179467

Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Imeri, Faik; Homann, Thomas; Kleuser, Burkhard; Stark, Holger; Huwiler, Andrea (2021). ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo. Molecules, 26(17) Molecular Diversity Preservation International MDPI 10.3390/molecules26175134

Imeri, Faik; Stepanovska Tanturovska, Bisera; Schwalm, Stephanie; Saha, Sarbari; Zeng-Brouwers, Jinyang; Pavenstädt, Herrmann; Pfeilschifter, Josef; Schaefer, Liliana; Huwiler, Andrea (2021). Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice. Matrix biology, 98, pp. 32-48. Elsevier 10.1016/j.matbio.2021.05.003

Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Imeri, Faik; Fallegger, Daniel; Zivkovic, Aleksandra; Schwalm, Stephanie; Enzmann, Gaby; Blankenbach, Kira; Meyer zu Heringdorf, Dagmar; Homann, Thomas; Kleuser, Burkhard; Pfeilschifter, Josef; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2014). Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice. Neuropharmacology, 85, pp. 314-327. Elsevier 10.1016/j.neuropharm.2014.05.012

Imeri, Faik; Jashri, Ahmed; Bullazhi, Lulzime; Shabani, Agim; Mikhova, Bozhana; Dräger, Gerald; Popovski, Emil; Huwiler, Andrea (2014). Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death. Bioorganic & medicinal chemistry, 22(9), pp. 2655-2660. Elsevier 10.1016/j.bmc.2014.03.026

Inderkum, Andrea

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Iype, Joseena Mariam

Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x

Jakob, Stephan

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

von Gunten, Stephan; Jakob, Stephan M; Geering, Barbara; Takala, Jukka; Simon, Hans-Uwe (2009). Different patterns of Siglec-9-mediated neutrophil death responses in septic shock. Shock, 32(4), pp. 386-92. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181a1bc98

Jandus, Camilla

Démoulins, Thomas; Bassi, Isabelle; Thomann-Harwood, Lisa; Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan; Mc Cullogh, Kenneth C (2013). Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells. Nanomedicine-Nanotechnology Biology and Medicine, 9(6), pp. 806-817. Elsevier 10.1016/j.nano.2013.01.002

Braun, Marion; Jandus, Camilla; Maurer, Patrik; Hammann-Haenni, Anya; Schwarz, Katrin; Bachmann, Martin F; Speiser, Daniel E; Romero, Pedro (2012). Virus-like particles induce robust human T-helper cell responses. European journal of immunology, 42(2), pp. 330-40. Weinheim: Wiley-VCH 10.1002/eji.201142064

Baumgaertner, Petra; Jandus, Camilla; Rivals, Jean-Paul; Derré, Laurent; Lövgren, Tanja; Baitsch, Lukas; Guillaume, Philippe; Luescher, Immanuel F; Berthod, Gregoire; Matter, Maurice; Rufer, Nathalie; Michielin, Olivier; Speiser, Daniel E (2012). Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells. International journal of cancer, 130(11), pp. 2607-17. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.26297

Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan (2011). Targeting siglecs--a novel pharmacological strategy for immuno- and glycotherapy. Biochemical pharmacology, 82(4), pp. 323-32. New York, N.Y.: Elsevier 10.1016/j.bcp.2011.05.018

Derré, Laurent; Jandus, Camilla; Baumgaertner, Petra; Posevitz, Vilmos; Devêvre, Estelle; Romero, Pedro; Speiser, Daniel E (2010). Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses. Methods in molecular biology, 626, pp. 231-249. Totowa, N.J.: Humana Press 10.1007/978-1-60761-585-9_16

Derré, Laurent; Rivals, Jean-Paul; Jandus, Camilla; Pastor, Sonia; Rimoldi, Donata; Romero, Pedro; Michielin, Olivier; Olive, Daniel; Speiser, Daniel E (2010). BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. Journal of clinical investigation, 120(1), pp. 157-67. Ann Arbor, Mich.: American Society for Clinical Investigation 10.1172/JCI40070

Jenni, Aurelio Leandro

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Juillerat, Pascal

Schoepfer, Alain M; Henchoz, Sarah; Biedermann, Luc; Schreiner, Philipp; Greuter, Thomas; Reinhard, Antoine; Senn, Jonduri; Franke, Annett; Burri, Emanuel; Juillerat, Pascal; Simon, Hans-Uwe; Straumann, Alex; Safroneeva, Ekaterina; Godat, Sébastien (2021). Technical feasibility, clinical effectiveness, and safety of esophageal stricture dilation using a novel endoscopic attachment cap in adults with eosinophilic esophagitis. Gastrointestinal endoscopy, 94(5), 912-919.e2. Elsevier 10.1016/j.gie.2021.05.017

Jörg, Lukas

Plattner, Kevin; Sousa Augusto, Gilles; Muerner, Lukas; von Gunten, Stephan; Jörg, Lukas; Engeroff, Paul; Bachmann, Martin F; Vogel, Monique (2023). IgE glycosylation is essential for the function of omalizumab. Allergy, 78(9), pp. 2546-2549. Wiley 10.1111/all.15748

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Karamitopoulou Diamantis, Evanthia

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Kassahn, Daniela

Kassahn, D; Nachbur, U; Conus, S; Micheau, O; Schneider, P; Simon, H-U; Brunner, T (2009). Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell death and differentiation, 16(1), pp. 115-24. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.133

Katsaros, Christos

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Kouskoura, Thaleia; Katsaros, Christos; von Gunten, Stephan (2017). The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM). Frontiers in physiology, 8(67), p. 67. Frontiers Research Foundation 10.3389/fphys.2017.00067

Kaufmann, Thomas

Lambrecht, Rebekka; Rudolf, Franziska; Ückert, Anna-Katharina; Sladky, Valentina C; Phan, Truong San; Jansen, Jasmin; Naim, Samara; Kaufmann, Thomas; Keogh, Adrian; Kirschnek, Susanne; Mangerich, Aswin; Stengel, Florian; Leist, Marcel; Villunger, Andreas; Brunner, Thomas (2024). Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis. Cell death and differentiation, 31(1), pp. 119-131. Nature Publishing Group 10.1038/s41418-023-01245-7

Vitale, Ilio; Pietrocola, Federico; Guilbaud, Emma; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostini, Massimiliano; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Aqeilan, Rami I; Arama, Eli; Baehrecke, Eric H; Balachandran, Siddharth; Bano, Daniele; Barlev, Nickolai A; Bartek, Jiri; Bazan, Nicolas G; ... (2023). Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell death and differentiation, 30(5), pp. 1097-1154. Nature Publishing Group 10.1038/s41418-023-01153-w

Kaufmann, Thomas; Simon, Hans-Uwe (2023). Pharmacological Induction of Granulocyte Cell Death As Therapeutic Strategy. Annual review of pharmacology and toxicology, 63, pp. 231-247. Annual Reviews Inc. 10.1146/annurev-pharmtox-051921-115130

Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Meinhardt, Anna-Lena; Munkhbaatar, Enkhtsetseg; Höckendorf, Ulrike; Dietzen, Michelle; Dechant, Marta; Anton, Martina; Jacob, Anne; Steiger, Katja; Weichert, Wilko; Brcic, Luka; McGranahan, Nicholas; Branca, Caterina; Kaufmann, Thomas; Dengler, Michael A; Jost, Philipp J (2022). The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner. Oncogene, 41(9), pp. 1376-1382. Springer Nature 10.1038/s41388-021-02161-1

Bachmeier-Zbären, Noemi; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). Mast cell activation test (In Press). In: Reference Module in Food Science. Elsevier 10.1016/B978-0-323-96018-2.00032-8

Naim, Samara; Fernández-Marrero, Yuniel; De Brot, Simone; Bachmann, Daniel; Kaufmann, Thomas (2021). Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice. International journal of molecular sciences, 22(6) MDPI 10.3390/ijms22063281

Burgener, Sabrina Sofia; Brügger, Melanie; Leborgne, Nathan Georges François; Sollberger, Sophia; Basilico, Paola; Kaufmann, Thomas; Bird, Phillip Ian; Benarafa, Charaf (2021). Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells. Frontiers in cell and developmental biology, 9, p. 630166. Frontiers 10.3389/fcell.2021.630166

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Naim, Samara; Kaufmann, Thomas (2020). The Multifaceted Roles of the BCLL-2 Family Member BOK. Frontiers in cell and developmental biology, 8 Frontiers 10.3389/fcell.2020.574338

Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Owsley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2020). Correction: TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell death & disease, 11(1), p. 56. Springer Nature 10.1038/s41419-020-2261-2

Rohner, Lionel; Reinhart, Ramona; Iype, Joseena; Bachmann, Sofia; Kaufmann, Thomas; Fux, Michaela (2020). Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Scientific reports, 10(1), p. 222. Springer Nature 10.1038/s41598-019-57000-x

Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Crowley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2019). TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell death & disease, 10(10), p. 700. Nature Publishing Group 10.1038/s41419-019-1938-x

Srivastava, Rahul; Cao, Zhipeng; Nedeva, Christina; Naim, Samara; Bachmann, Daniel; Rabachini, Tatiana; Gangoda, Lahiru; Shahi, Sanjay; Glab, Jason; Menassa, Joseph; Osellame, Laura; Nelson, Tao; Fernández Marrero, Yuniel; Brown, Fiona; Wei, Andrew; Ke, Francine; O'Reilly, Lorraine; Doerflinger, Marcel; Allison, Cody; Kueh, Andrew; ... (2019). BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 116(31), pp. 15469-15474. National Academy of Sciences NAS 10.1073/pnas.1904523116

Fernández Marrero, Yuniel; Bachmann, Daniel; Lauber, Emanuel; Kaufmann, Thomas (2018). Negative Regulation of BOK Expression by Recruitment of TRIM28 to Regulatory Elements in Its 3' Untranslated Region. iScience, 9, pp. 461-474. Elsevier 10.1016/j.isci.2018.11.005

Rohner, Lionel; Reinhart, Ramona; Hagmann, Björn; Odermatt, Andrea; Babirye, Annet; Kaufmann, Thomas; Fux, Michaela (2018). FcɛRI cross-linking and IL-3 protect human basophils from intrinsic apoptotic stress. The Journal of allergy and clinical immunology, 142(5), 1647-1650.e3. Elsevier 10.1016/j.jaci.2018.06.040

Reinhart, Ramona; Kaufmann, Thomas (2018). IL-4 enhances survival of in vitro-differentiated mouse basophils through transcription-independent signaling downstream of PI3K. Cell death & disease, 9(7), p. 713. Nature Publishing Group 10.1038/s41419-018-0754-z

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V; Arama, Eli; Baehrecke, Eric H; Barlev, Nickolai A; Bazan, Nicolas G; Bernassola, Francesca; Bertrand, Mathieu J M; Bianchi, Katiuscia; Blagosklonny, Mikhail V; ... (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell death and differentiation, 25(3), pp. 486-541. Nature Publishing Group 10.1038/s41418-017-0012-4

Wicki, Simone; Gurzeler, Ursina; Corazza, Nadia; Genitsch, Vera; Wong, Wendy Wei-Lynn; Kaufmann, Thomas (2018). Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss. International journal of molecular sciences, 19(3) Molecular Diversity Preservation International MDPI 10.3390/ijms19030684

Reinhart, Ramona; Rohner, Lionel; Wicki, Simone; Fux, Michaela; Kaufmann, Thomas (2018). BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells. Cell death and differentiation, 25(1), pp. 204-216. Nature Publishing Group 10.1038/cdd.2017.154

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40

Sharma, Sachin; Kaufmann, Thomas; Biswas, Subhrajit (2017). Impact of inhibitor of apoptosis proteins on immune modulation and inflammation. Immunology and cell biology, 95(3), pp. 236-243. Nature Publishing Group 10.1038/icb.2016.101

Fernandez-Marrero, Yuniel; Bleicken, Stephanie; Das, Kushal Kumar; Bachmann, Daniel; Kaufmann, Thomas; Garcia-Saez, Ana J (2017). The membrane activity of BOK involves formation of large, stable toroidal pores and is promoted by cBID. FEBS journal, 284(5), pp. 711-724. Wiley-Blackwell 10.1111/febs.14008

Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, Michaela (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850

Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311

Tuzlak, Selma; Kaufmann, Thomas; Villunger, Andreas (2016). Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis. Genes & development, 30(19), pp. 2133-2151. Cold Spring Harbor Laboratory Press 10.1101/gad.289298.116

Fernandez Marrero, Yuniel; Spinner, S; Jost, P J; Kaufmann, Thomas (2016). Survival control of malignant lymphocytes by anti-apoptotic MCL-1. Leukemia, 30(11), pp. 2152-2159. Nature Publishing Group 10.1038/leu.2016.213

D'Orsi, Beatrice; Engel, Tobias; Pfeiffer, Shona; Nandi, Saheli; Kaufmann, Thomas; Henshall, David C; Prehn, Jochen H M (2016). Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. Journal of neuroscience, 36(16), pp. 4564-4578. Society for Neuroscience 10.1523/JNEUROSCI.3780-15.2016

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Reinhart, Ramona; Wicki, Simone; Kaufmann, Thomas (2016). In Vitro Differentiation of Mouse Granulocytes. Methods in molecular biology, 1419, pp. 95-107. Humana Press 10.1007/978-1-4939-3581-9_8

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Targeting disease by immunomodulation. Cell death and differentiation, 22(2), pp. 185-186. Nature Publishing Group 10.1038/cdd.2014.166

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137

Kaufmann, Thomas; Reinhart, Ramona; Wicki, Simone (2015). In vitro differentiation of mouse granulocytes. Programmed Cell Death: Methods and Protocols (In Press). In: Puthalakath, Hamsa; Hawkins, Christine (eds.) Programmed Cell Death: Methods and Protocols. Methods in Molecular Biology. Humana Press

Andree, Maria; Seeger, Jens M.; Schüll, Stephan; Coutelle, Oliver; Wagner-Stippich, Diana; Wiegmann, Katja; Wunderlich, Claudia M.; Birkmann, Kerstin; Broxtermann, Pia; Witt, Axel; Fritsch, Melanie; Martinelli, Paola; Bielig, Harald; Lamkemeyer, Tobias; Rugarli, Elena I.; Kaufmann, Thomas; Sterner-Kock, Anja; Wunderlich, F. Thomas; Villunger, Andreas; Martins, L. Miguel; ... (2014). BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO journal, 33(19), pp. 2171-2187. Nature Publishing Group 10.15252/embj.201387244

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Yabal, Monica; Müller, Nicole; Adler, Heiko; Knies, Nathalie; Gross, Christina J.; Damgaard, Rune Busk; Kanegane, Hirokazu; Ringelhan, Marc; Kaufmann, Thomas; Heikenwächter, Mathias; Strasser, Andreas; Gross, Olaf; Ruland, Jürgen; Peschel, Christian; Gyrd-Hansen, Mads; Jost, Philipp J. (2014). XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation. Cell reports, 7(6), pp. 1795-1808. Cell Press 10.1016/j.celrep.2014.05.008

Herold, Marco J.; Rohrbeck, Leona; Lang, Mathias J.; Grumont, Raelene; Gerondakis, Steve; Tai, Lin; Bouillet, Philippe; Kaufmann, Thomas; Strasser, Andreas (2013). Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein. EMBO REPORTS, 14(11), pp. 992-998. Nature 10.1038/embor.2013.152

Schulman, Jacqualyn J; Wright, Fiorrest A; Kaufmann, Thomas; Wojcikiewicz, Richard J H (2013). The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage. Journal of biological chemistry, 288(35), pp. 25340-25349. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.496570

Ke, Francine; Kaufmann, Thomas; Bouillet, Philippe; Strasser, Andreas; Kerr, Jeffrey; Voss, Anne K (2013). Consequences of the combined loss of BOK and BAK or BOK and BAX. Cell death & disease, 4(6), e650. Nature Publishing Group 10.1038/cddis.2013.176

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Kaufmann, Thomas; Strasser, Andreas; Jost, Philipp J (2012). Fas death receptor signalling: roles of Bid and XIAP. Cell death and differentiation, 19(1), pp. 42-50. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.121

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3(12), e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Corazza, Nadia; Kaufmann, Thomas (2012). Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models. Allergy, 67(12), pp. 1483-90. Oxford: Wiley-Blackwell 10.1111/all.12065

Damgaard, Rune Busk; Nachbur, Ueli; Yabal, Monica; Wong, Wendy Wei-Lynn; Fiil, Berthe Katrine; Kastirr, Mischa; Rieser, Eva; Rickard, James Arthur; Bankovacki, Aleksandra; Peschel, Christian; Ruland, Juergen; Bekker-Jensen, Simon; Mailand, Niels; Kaufmann, Thomas; Strasser, Andreas; Walczak, Henning; Silke, John; Jost, Philipp J; Gyrd-Hansen, Mads (2012). The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Molecular cell, 46(6), pp. 746-58. Cambridge, Mass.: Cell Press 10.1016/j.molce1.2012.04.014

Ke, Francine; Voss, Anne; Kerr, Jeffrey; O'Reilly, Lorraine; Tai, Lin; Echeverry, Nohemy; Bouillet, Philippe; Strasser, Andreas; Kaufmann, Thomas (2012). BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice. Cell death and differentiation, 19(6), pp. 915-25. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.210

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Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2(6), e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206

Jost, Philipp J; Kaufmann, Thomas (2010). Cancer caused by too much apoptosis--an intriguing contradiction? Hepatology, 51(4), pp. 1110-1112. Hoboken, N.J.: Wiley Interscience 10.1002/hep.23314

Jost, Philipp J; Grabow, Stephanie; Gray, Daniel; McKenzie, Mark D; Nachbur, Ueli; Huang, David C S; Bouillet, Philippe; Thomas, Helen E; Borner, Christoph; Silke, John; Strasser, Andreas; Kaufmann, Thomas (2009). XIAP discriminates between type I and type II FAS-induced apoptosis. Nature, 460(7258), pp. 1035-1039. London: Macmillan Journals Ltd. 10.1038/nature08229

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O'Reilly, Lorraine A; Kruse, Elizabeth A; Puthalakath, Hamsa; Kelly, Priscilla N; Kaufmann, Thomas; Huang, David C S; Strasser, Andreas (2009). MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation. Journal of immunology, 183(1), pp. 261-9. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803853

Kaufmann, Thomas; Jost, Philipp J; Pellegrini, Marc; Puthalakath, Hamsa; Gugasyan, Raffi; Gerondakis, Steve; Cretney, Erika; Smyth, Mark J; Silke, John; Hakem, Razq; Bouillet, Philippe; Mak, Tak W; Dixit, Vishva M; Strasser, Andreas (2009). Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. Immunity, 30(1), pp. 56-66. Cambridge, Mass.: Cell Press 10.1016/j.immuni.2008.10.017

Jabbour, A M; Heraud, J E; Daunt, C P; Kaufmann, T; Sandow, J; O'Reilly, L A; Callus, B A; Lopez, A; Strasser, A; Vaux, D L; Ekert, P G (2009). Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation, 16(4), pp. 555-63. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.179

Walter, Dorothée; Schmich, Kathrin; Vogel, Sandra; Pick, Robert; Kaufmann, Thomas; Hochmuth, Florian Christoph; Haber, Angelika; Neubert, Karin; McNelly, Sabine; von Weizsäcker, Fritz; Merfort, Irmgard; Maurer, Ulrich; Strasser, Andreas; Borner, Christoph (2008). Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Hepatology, 48(6), pp. 1942-53. Hoboken, N.J.: Wiley Interscience 10.1002/hep.22541

McKenzie, Mark D; Carrington, Emma M; Kaufmann, Thomas; Strasser, Andreas; Huang, David C S; Kay, Thomas W H; Allison, Janette; Thomas, Helen E (2008). Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells. Diabetes, 57(5), pp. 1284-92. Alexandria, Va.: American Diabetes Association 10.2337/db07-1692

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Keogh, Adrian

Lambrecht, Rebekka; Rudolf, Franziska; Ückert, Anna-Katharina; Sladky, Valentina C; Phan, Truong San; Jansen, Jasmin; Naim, Samara; Kaufmann, Thomas; Keogh, Adrian; Kirschnek, Susanne; Mangerich, Aswin; Stengel, Florian; Leist, Marcel; Villunger, Andreas; Brunner, Thomas (2024). Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis. Cell death and differentiation, 31(1), pp. 119-131. Nature Publishing Group 10.1038/s41418-023-01245-7

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Saliakoura, Maria; Konstantinidou, Georgia (2023). Lipid Metabolic Alterations in KRAS Mutant Tumors: Unmasking New Vulnerabilities for Cancer Therapy. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021793

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Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

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Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2015). Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. Journal of molecular medicine JMM, 93(2), pp. 159-164. Springer 10.1007/s00109-014-1241-3

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2014). Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy, 10(2), pp. 372-373. Landes Bioscience 10.4161/auto.27163

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2013). Targeting autophagy as a potential therapeutic approach for melanoma therapy. Seminars in Cancer Biology, 5(23), pp. 352-360. Elsevier 10.1016/j.semcancer.2013.06.008

Lochmatter, Didier

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Loforese, Giulio

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Losdat, Sylvain Pierre

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

Bär, Sarah; Kavaliauskaite, Raminta; Otsuka, Tatsuhiko; Ueki, Yasushi; Häner, Jonas D; Siontis, George C M; Stortecky, Stefan; Shibutani, Hiroki; Temperli, Fabrice; Kaiser, Christoph; Iglesias, Juan; Jan van Geuns, Robert; Daemen, Joost; Spirk, David; Engstrøm, Thomas; Lang, Irene; Windecker, Stephan; Koskinas, Konstantinos C; Losdat, Sylvain and Räber, Lorenz (2023). Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention, 19(4), e286-e296. Europa Digital & Publishing 10.4244/EIJ-D-23-00201

Räber, Lorenz; Ueki, Yasushi; Otsuka, Tatsuhiko; Losdat, Sylvain; Häner, Jonas D; Lonborg, Jacob; Fahrni, Gregor; Iglesias, Juan F; van Geuns, Robert-Jan; Ondracek, Anna S; Radu Juul Jensen, Maria D; Zanchin, Christian; Stortecky, Stefan; Spirk, David; Siontis, George C; Saleh, Lanja; Matter, Christian M; Daemen, Joost; Mach, François; Heg, Dik; ... (2022). Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial. JAMA - the journal of the American Medical Association, 327(18), pp. 1771-1781. American Medical Association 10.1001/jama.2022.5218

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Zanchin, Christian; Ueki, Yasushi; Losdat, Sylvain; Fahrni, Gregor; Daemen, Joost; Ondracek, Anna S; Häner, Jonas D.; Stortecky, Stefan; Otsuka, Tatsuhiko; Siontis, George C.M.; Rigamonti, Fabio; Radu, Maria; Spirk, David; Kaiser, Christoph; Engstrom, Thomas; Lang, Irene; Koskinas, Konstantinos C.; Räber, Lorenz (2021). In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study. European heart journal - cardiovascular imaging, 22(7), pp. 824-834. Oxford University Press 10.1093/ehjci/jez318

Losmanová, Tereza

Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

Lyck, Ruth

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Macpherson, Andrew

Rollenske, Tim; Burkhalter, Sophie; Muerner, Lukas; von Gunten, Stephan; Lukasiewicz, Jolanta; Wardemann, Hedda; Macpherson, Andrew J. (2021). Parallelism of intestinal secretory IgA shapes functional microbial fitness. Nature, 598(7882), pp. 657-661. Springer Nature 10.1038/s41586-021-03973-7

Maire, Renaud Sylvain

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Manaila, Roxana

Hafizi, Redona; Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Schwalm, Stephanie; Trautmann, Sandra; Wenger, Roland H; Pfeilschifter, Josef; Huwiler, Andrea (2022). Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells. International journal of molecular sciences, 23(11) MDPI 10.3390/ijms23115882

Manaila, Roxana-Cristiana

Manaila, Roxana-Cristiana; Huwiler, Andrea (2024). [Polypharmacy in acute and chronic kidney diseases]. Innere Medizin, 65(1), pp. 22-28. Springer 10.1007/s00108-023-01634-7

Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Pavenstädt, Hermann; Pfeilschifter, Josef; Huwiler, Andrea (2023). Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043267

Stepanovska Tanturovska, Bisera; Manaila, Roxana; Fabbro, Doriano; Huwiler, Andrea (2023). Lipids as Targets for Renal Cell Carcinoma Therapy. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043272

Mandel, Therese

Reinhardt, Didier; Pesce, Eva-Rachele; Stieger, Pia; Mandel, Therese; Baltensperger, Kurt; Bennett, Malcolm; Traas, Jan; Friml, Jiří; Kuhlemeier, Cris (2003). Regulation of phyllotaxis by polar auxin transport. Nature, 426(6964), pp. 255-260. Macmillan Journals Ltd. 10.1038/nature02081

Maneva Timcheva, Tankica

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Marinoni, Ilaria

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

Markov, Nikita

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14 Frontiers Research Foundation 10.3389/fimmu.2023.1331151

Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Markov, Nikita; Simon, Hans-Uwe (2020). IL-37: A new player in the chronic rhinosinusitis arena. The Journal of allergy and clinical immunology, 145(1), pp. 105-107. Elsevier 10.1016/j.jaci.2019.10.018

Marti, Thomas

Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Maskey, Dipak

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

McCullough, Kenneth

Démoulins, Thomas; Schulze, Kai; Ebensen, Thomas; Techakriengkrai, Navapon; Nedumpun, Teerawut; Englezou, Pavlos C; Gerber, Markus; Hlushchuk, Ruslan; Toledo, Darien; Djonov, Valentin; von Gunten, Stephan; McCullough, Kenneth C; Liniger, Matthias; Guzmán, Carlos A; Suradhat, Sanipa; Ruggli, Nicolas (2023). Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases. Nanomedicine : nanotechnology, biology, and medicine, 49(102655), p. 102655. Elsevier 10.1016/j.nano.2023.102655

Medova, Michaela

Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

Meneses Moreno, Niurka

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Merz, Christina

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Stoeckle, Christina; Rota, Ioanna A.; Tolosa, Eva; Haller, Christoph; Melms, Arthur; Adamopoulou, Eleni (2013). Isolation of myeloid dendritic cells and epithelial cells from human thymus. Journal of visualized experiments, 79(79), e50951. MYJoVE Corporation 10.3791/50951

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

Adamopoulou, Eleni; Tenzer, Stefan; Hillen, Nina; Klug, Paul; Rota, Ioanna A.; Tietz, Silvia; Gebhardt, Madlen; Stevanovic, Stefan; Schild, Hansjörg; Tolosa, Eva; Melms, Arthur; Stoeckle, Christina (2013). Exploring the MHC-peptide matrix of central tolerance in the human thymus. Nature communications, 4(2039), p. 2039. Nature Publishing Group 10.1038/ncomms3039

Stoeckle, C.; Simon, Hans-Uwe (2013). CD8(+) T cells producing IL-3 and IL-5 in non-IgE-mediated eosinophilic diseases. Allergy, 68(12), pp. 1622-1628. Wiley-Blackwell 10.1111/all.12311

Stoeckle, Christina; Quecke, Paula; Rückrich, Thomas; Burster, Timo; Reich, Michael; Weber, Ekkehard; Kalbacher, Hubert; Driessen, Christoph; Melms, Arthur; Tolosa, Eva (2012). Cathepsin S dominates autoantigen processing in human thymic dendritic cells. Journal of autoimmunity, 38(4), pp. 332-43. Amsterdam: Elsevier 10.1016/j.jaut.2012.02.003

Lammel, Verena; Stoeckle, Christina; Padberg, Barbara; Zweifel, Roland; Kienle, Dirk L; Reinhart, Walter H; Simon, Hans-Uwe (2012). Hypereosinophilia driven by GM-CSF in large-cell carcinoma of the lung. Lung cancer, 76(3), pp. 493-5. Amsterdam: Elsevier 10.1016/j.lungcan.2012.02.014

Geering Truffer, Barbara; Schmidt-Mende, Jan; Federzoni, Elena; Stoeckle, Christina; Simon, Hans-Uwe (2011). Protein overexpression following lentiviral infection of primary mature neutrophils is due to pseudotransduction. Journal of immunological methods, 373(1-2), pp. 209-18. Amsterdam: Elsevier 10.1016/j.jim.2011.08.024

Sevenich, Lisa; Hagemann, Sascha; Stoeckle, Christina; Tolosa, Eva; Peters, Christoph; Reinheckel, Thomas (2010). Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice. Biochimie, 92(11), pp. 1674-80. Paris: Elsevier Masson SAS 10.1016/j.biochi.2010.03.014

Seizer, Peter; Schiemann, Susanne; Merz, Tobias; Daub, Karin; Bigalke, Boris; Stellos, Konstantinos; Müller, Iris; Stöckle, Christina; Müller, Karin; Gawaz, Meinrad; May, Andreas E (2010). CD36 and macrophage scavenger receptor a modulate foam cell formation via inhibition of lipid-laden platelet phagocytosis. Seminars in thrombosis and hemostasis, 36(2), pp. 157-62. New York, N.Y.: Thieme Medical Publishers 10.1055/s-0030-1251499

Luther, Claudia; Adamopoulou, Eleni; Stoeckle, Christina; Brucklacher-Waldert, Verena; Rosenkranz, Daniela; Stoltze, Lars; Lauer, Sigrid; Poeschel, Simone; Melms, Arthur; Tolosa, Eva (2009). Prednisolone treatment induces tolerogenic dendritic cells and a regulatory milieu in myasthenia gravis patients. Journal of immunology, 183(2), pp. 841-8. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0802046

Stoeckle, Christina; Gouttefangeas, Cécile; Hammer, Michael; Weber, Ekkehard; Melms, Arthur; Tolosa, Eva (2009). Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs. Experimental hematology, 37(2), pp. 266-75. New York, N.Y.: Elsevier 10.1016/j.exphem.2008.10.011

Stoeckle, Christina; Sommandas, Vinod; Adamopoulou, Eleni; Belisle, Kurt; Schiekofer, Stephan; Melms, Arthur; Weber, Ekkehard; Driessen, Christoph; Boehm, Bernhard O; Tolosa, Eva; Burster, Timo (2009). Cathepsin G is differentially expressed in primary human antigen-presenting cells. Cellular immunology, 255(1-2), pp. 41-5. San Diego, Calif.: Elsevier 10.1016/j.cellimm.2008.10.001

Stoeckle, Christina; Tolosa, Eva (2009). Antigen Processing and Presentation in Multiple Sclerosis. Results and problems in cell differentiation, 51, pp. 149-172. Berlin: Springer

Stoeckle, Christina; Gleske, Anne-Kathrin (2009). Immunotherapy: from basic research to clinical applications. Cancer immunology, immunotherapy, 58(7), pp. 1129-36. Heidelberg: Springer 10.1007/s00262-008-0544-z

Miescher-Granger, Sylvia M.

von Gunten, Stephan; Vogel, Monique; Schaub, Alexander; Stadler, Beda M; Miescher, Sylvia; Crocker, Paul R; Simon, Hans-Uwe (2007). Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. Journal of allergy and clinical immunology, 119(4), pp. 1005-11. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.01.023

Minier, Frédéric

Baur, Roland; Minier, Frédéric; Sigel, Erwin (2006). A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits. FEBS letters, 580(6), pp. 1616-20. Amsterdam: Elsevier 10.1016/j.febslet.2006.02.002

Mitter, Vera Ruth

Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2023). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. (In Press). Thrombosis and haemostasis Thieme 10.1055/a-2156-7872

Moreno Bermudez, Josue Manuel

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Morshed, Md. Mahbubul

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x

Mullis, Primus-Eugen

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Petkovic, Vibor; Salemi, Souzan; Vassella, Erik; Karamitopoulou-Diamantis, Evanthia; Meinhardt, Udo J; Flück, Christa E; Mullis, Primus E (2007). Leydig-cell tumour in children: variable clinical presentation, diagnostic features, follow-up and genetic analysis of four cases. Hormone research, 67(2), pp. 89-95. Basel: Karger 10.1159/000096356

Salemi, Souzan; Yousefi, Shida; Eblé, Andrée; Deladoëy, Johnny; Mullis, Primus E (2006). Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis. Hormone research, 65(3), pp. 132-41. Basel: Karger 10.1159/000091607

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Deng, Haibin; Ge, Huixiang; Dubey, Christelle; Losmanova, Tereza; Medova, Michaela; Konstantinidou, Georgia; Mutlu, Seyran Mathilde; Birrer, Fabienne Esther; Brodie, Tess Melinda; Stroka, Deborah; Wang, Wenxiang; Peng, Ren-Wang; Dorn, Patrick; Marti, Thomas Michael (2023). An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1. Cancer immunology, immunotherapy : CII, 72(12), pp. 4457-4470. Springer 10.1007/s00262-023-03542-z

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Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Peng, Shuang

Peng, Shuang; Gao, Jian; Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2023). Established and emerging roles for mitochondria in neutrophils. Immunological reviews, 314(1), pp. 413-426. Wiley-Blackwell 10.1111/imr.13158

Peng, Shuang; Stojkov, Darko; Gao, Jian; Oberson, Kevin; Latzin, Philipp; Casaulta, Carmen; Yousefi, Shida; Simon, Hans-Uwe (2022). Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils. PLoS biology, 20(9), e3001794. Public Library of Science 10.1371/journal.pbio.3001794

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

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Perren, Aurel

April-Monn, Simon Leonhard; Andreasi, Valentina; Schiavo Lena, Marco; Sadowski, Martin Carl; Kim-Fuchs, Corina; Buri, Michelle Claudine; Ketkar, Avanee; Maire, Renaud; Di Domenico, Annunziata; Schrader, Jörg; Muffatti, Francesca; Doglioni, Claudio; Partelli, Stefano; Falconi, Massimo; Perren, Aurel; Marinoni, Ilaria (2021). EZH2 Inhibition as New Epigenetic Treatment Option for Pancreatic Neuroendocrine Neoplasms (PanNENs). Cancers, 13(19) MDPI AG 10.3390/cancers13195014

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He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

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Vichalkovski, Anton; Kotevic, Ivana; Gebhardt, Niculina; Kaderli, Reto; Porzig, Hartmut (2006). Tyrosine kinase modulation of protein kinase C activity regulates G protein-linked Ca2+ signaling in leukemic hematopoietic cells. Cell calcium, 39(6), pp. 517-28. Amsterdam: Elsevier 10.1016/j.ceca.2006.03.001

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Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

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Abjaude, Walason; Prati, Bruna; Munford, Veridiana; Montenegro, Aline; Lino, Vanesca; Herbster, Suellen; Rabachini, Tatiana; Termini, Lara; Menck, Carlos Frederico Martins; Boccardo, Enrique (2022). ATM Pathway Is Essential for HPV-Positive Human Cervical Cancer-Derived Cell Lines Viability and Proliferation. Pathogens, 11(6), p. 637. MDPI AG 10.3390/pathogens11060637

Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Montani, Matteo; Loforese, Giulio; Sladky, Valentina; He, Zhaoyue; Bachmann, Daniel; Wicki, Simone; Villunger, Andreas; Keogh-Stroka, Deborah M.; Kaufmann, Thomas (2018). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell death and differentiation, 25(4), pp. 706-718. Nature Publishing Group 10.1038/s41418-017-0008-0

Moravcikova, Erika; Krepela, Evzen; Donnenberg, Vera S; Donnenberg, Albert D; Benkova, Kamila; Rabachini de Almeida, Tatiana; Fernández Marrero, Yuniel; Bachmann, Daniel; Kaufmann, Thomas (2017). BOK displays cell death-independent tumor suppressor activity in non-small cell lung carcinoma. International journal of cancer, 141(10), pp. 2050-2061. Wiley-Blackwell 10.1002/ijc.30906

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

Walter, Stephen D.; Riddell, Corinne A.; Rabachini, Tatiana; Villa, Luisa L.; Franco, Eduardo L. (2013). Accuracy of p53 codon 72 polymorphism status determined by multiple laboratory methods: a latent class model analysis. PLoS ONE, 8(2), e56430. Public Library of Science 10.1371/journal.pone.0056430

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Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

Bürgler, Christina; Dutoit, Danielle; Radonjic-Hoesli, Susanne; Thormann, Kathrin; Lehmann, Mathias; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2023). Dupilumab normalizes correlates of lysosomal function in atopic dermatitis (In Press). JEADV Clinical Practice Wiley 10.1002/jvc2.307

Radonjic-Hoesli, Susanne; Pavlov, Nikolay; Simon, Hans-Uwe; Simon, Dagmar (2022). Are blood cytokines reliable biomarkers of allergic disease diagnosis and treatment responses? Journal of allergy and clinical immunology, 150(2), pp. 251-258. Elsevier 10.1016/j.jaci.2022.06.008

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Radonjic-Hoesli, Susanne; Brüggen, Marie-Charlotte; Feldmeyer, Laurence; Simon, Hans-Uwe; Simon, Dagmar (2021). Eosinophils in skin diseases. Seminars in immunopathology, 43(3), pp. 393-409. Springer 10.1007/s00281-021-00868-7

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879

Simon, Hans-Uwe; Radonjic, Susanne Irene (2016). Eosinophile Granulozyten. In: Biedermann, Tilo; Heppt, Werner; Renz, Harald; Röcken, Martin (eds.) Allergologie (pp. 77-85). Berlin, Heidelberg: Springer 10.1007/978-3-642-37203-2_7

Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570

Radonjic-Hösli, Susanne; Simon, Hans-Uwe (2014). Eosinophils. Chemical immunology and allergy, 100, pp. 193-204. Karger 10.1159/000358735

Straumann, A.; Hoesli, S.; Bussmann, Ch.; Stuck, M.; Perkins, M.; Collins, L. P.; Payton, M.; Pettipher, R.; Hunter, M.; Steiner, J.; Simon, H.-U. (2013). Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis. Allergy, 68(3), pp. 375-385. Wiley-Blackwell 10.1111/all.12096

Roth, N; Städler, S; Lemann, M; Hösli, S; Simon, H-U; Simon, D (2011). Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. Allergy, 66(11), pp. 1477-86. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02694.x

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Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

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Knop, Janin; Spilgies, Lisanne M; Rufli, Stefanie; Reinhart, Ramona; Vasilikos, Lazaros; Yabal, Monica; Owsley, Erika; Jost, Philipp J; Marsh, Rebecca A; Wajant, Harald; Robinson, Mark D; Kaufmann, Thomas; Wong, W Wei-Lynn (2020). Correction: TNFR2 induced priming of the inflammasome leads to a RIPK1-dependent cell death in the absence of XIAP. Cell death & disease, 11(1), p. 56. Springer Nature 10.1038/s41419-020-2261-2

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Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Saliakoura, Maria; Rossi Sebastiano, Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Saliakoura, Maria; Reynoso-Moreno, Inés; Pozzato, Chiara; Rossi Sebastiano, Matteo; Galié, Mirco; Gertsch, Jürg; Konstantinidou, Georgia (2020). The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer. Oncogene, 39(14), pp. 2948-2960. Springer Nature 10.1038/s41388-020-1196-5

Sandbaumhüter, Friederike Andrea

Sandbaumhüter, Friederike Andrea; Haschke, Manuel Martin; Vogt, Bruno; Bohlender, Jürgen (2018). Medication adherence during laboratory workup for primary aldosteronism: pilot study. Patient preference and adherence, 12, pp. 2449-2455. Dove Medical Press 10.2147/PPA.S179488

Saurer, Leslie

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Schaffner, Thomas

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Schaller, André

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Schefold, Jörg Christian

Spinetti, Thibaud; Meisel, Christian; von Gunten, Stephan; Schefold, Joerg C. (2020). Immune biomarker-based enrichment in sepsis trials. Critical care, 24(1), p. 58. BioMed Central 10.1186/s13054-020-2774-1

Schindewolf, Marc

Sebastian, Tim; Barco, Stefano; Engelberger, Rolf P; Spirk, David; Schindewolf, Marc; Baumann, Frederic; Baumgartner, Iris; Kucher, Nils (2020). Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. European journal of vascular and endovascular surgery EJVES, 60(3), pp. 443-450. Elsevier 10.1016/j.ejvs.2020.05.011

Schittny, Johannes

Peter, Andreas B.; Schittny, Johannes C.; Niggli, Verena; Reuter, Harald; Sigel, Erwin (1991). The polarized distribution of poly(A+)-mRNA-induced functional ion channels in the Xenopus oocyte plasma membrane is prevented by anticytoskeletal drugs. Journal of cell biology, 114(3), pp. 455-464. Rockefeller Institute Press

Schlapbach, Christoph

Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

Schmid, Ines

Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Eveline; Schmid, Ines; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S and Simon, Hans-Uwe (2015). Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular cell, 57(6), pp. 1011-1021. Cell Press 10.1016/j.molcel.2015.01.026

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Schmid, Ralph

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Saliakoura, Maria; Rossi Sebastiano, Matteo; Pozzato, Chiara; Heidel, Florian H.; Schnöder, Tina M.; Savic Prince, Spasenija; Bubendorf, Lukas; Pinton, Paolo; Schmid, Ralph A.; Baumgartner, Johanna; Freigang, Stefan; Berezowska, Sabina A.; Rimessi, Alessandro; Konstantinidou, Georgia (2020). PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia. Nature cell biology, 22(11), pp. 1382-1395. Springer Nature 10.1038/s41556-020-00592-8

Schmidt, Jan

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Schneider, Christoph

von Gunten, Stephan; Schneider, Christoph; Imamovic, Lejla; Gorochov, Guy (2023). Antibody diversity in IVIG: Therapeutic opportunities for novel immunotherapeutic drugs. Frontiers in immunology, 14, p. 1166821. Frontiers Research Foundation 10.3389/fimmu.2023.1166821

Späth, Peter Julius; Schneider, Christoph; von Gunten, Stephan (2017). Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations. Archivum immunologiae et therapiae experimentalis, 65(3), pp. 215-231. Springer 10.1007/s00005-016-0422-x

Schneider, Christoph; Illi, Marlies; Lötscher, Marius; Wehrli, Marc; von Gunten, Stephan (2017). Isolation of Antibodies from Human Plasma, Saliva, Breast Milk, and Gastrointestinal Fluid. Methods in molecular biology, 1643, pp. 23-31. Springer 10.1007/978-1-4939-7180-0_3

Quast, Isaak; Keller, Christian W; Weber, Patrick; Schneider, Christoph; von Gunten, Stephan; Lünemann, Jan D (2016). Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation. Journal of neuroinflammation, 13, p. 42. BioMed Central 10.1186/s12974-016-0506-x

(2016). Protein-carbohydrate interactions in the human immune system (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Scholz, Irene

Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553

Schorer, Myriam Fabiola

Schorer, Myriam Fabiola; Simon, Dagmar (2016). Innate immune system crosstalk: Eosinophils mediate immune modulation of dendritic cells through exosomes as shuttle vectors of miRNA (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/jimmunol.1400028

von Gunten, Stephan; Schorer, Myriam Fabiola; Kollarik, M.; Beisswenger, C.; Lepper, P. M. (2013). Mechanisms and potential therapeutic targets in allergic inflammation: recent insights. Allergy, 68(12), pp. 1487-1498. Wiley-Blackwell 10.1111/all.12312

Schwalm, Stephanie

Beyoğlu, Diren; Schwalm, Stephanie; Semmo, Nasser; Huwiler, Andrea; Idle, Jeffrey R (2023). Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021407

Beyer, Sandra; Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2018). Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis. Cellular physiology and biochemistry, 47(6), pp. 2522-2533. Karger 10.1159/000491625

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Imeri, Faik; Schwalm, Stephanie; Lyck, Ruth; Zivkovic, Aleksandra; Stark, Holger; Engelhardt, Britta; Pfeilschifter, Josef; Huwiler, Andrea (2016). Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments. Neuropharmacology, 105, pp. 341-350. Elsevier 10.1016/j.neuropharm.2016.01.031

Imeri, Faik; Blanchard, Olivier; Jenni, Aurelio Leandro; Schwalm, Stephanie; Wünsche, Christin; Zivkovic, Aleksandra; Stark, Holger; Pfeilschifter, Josef; Huwiler, Andrea (2015). FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase. Naunyn-Schmiedeberg's archives of pharmacology, 388(12), pp. 1283-1292. Springer 10.1007/s00210-015-1159-5

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Wünsche, Christin; Koch, Alexander; Goldschmeding, Roel; Schwalm, Stephanie; Meyer Zu Heringdorf, Dagmar; Huwiler, Andrea; Pfeilschifter, Josef (2015). Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1851(5), pp. 519-526. Elsevier 10.1016/j.bbalip.2015.01.003

Schwalm, Stephanie; Pfeilschifter, Josef; Huwiler, Andrea (2010). Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation. British journal of pharmacology, 160(7), pp. 1641-51. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.00818.x

Förster, Ankathrin; Emmler, Tanja; Schwalm, Stephanie; Ebadi, Mahsa; Heringdorf, Dagmar Meyer Zu; Nieuwenhuis, Barbara; Kleuser, Burkhardt; Huwiler, Andrea; Pfeilschifter, Josef (2010). Glucocorticoids protect renal mesangial cells from apoptosis by increasing cellular sphingosine-1-phosphate. Kidney international, 77(10), pp. 870-9. New York, N.Y.: Nature Publishing Group 10.1038/ki.2010.62

Schären, Olivier Pascal

Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517

Schöni, Martin Heinrich

Altznauer, Frank; Martinelli, Sibylla; Yousefi, Shida; Thürig, Christine; Schmid, Inès; Conway, Edward M; Schöni, Martin H; Vogt, Peter; Mueller, Christoph; Fey, Martin F; Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2004). Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils. The Journal of experimental medicine, 199(10), pp. 1343-1354. Rockefeller Univ. Press 10.1084/jem.20032033

Schöpfer, Alain

Straumann, Alex; Bussmann, Christian; Zuber, Markus; Vannini, Simone; Simon, Hans-Uwe; Schoepfer, Alain (2008). Eosinophilic esophagitis: analysis of food impaction and perforation in 251 adolescent and adult patients. Clinical gastroenterology and hepatology, 6(5), pp. 598-600. Philadelphia, Pa.: Elsevier 10.1016/j.cgh.2008.02.003

Schürch, Christian

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Schürch, Stefan

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Sebastian, Tim

Sebastian, Tim; Spirk, David; Engelberger, Rolf P; Dopheide, Jörn F.; Baumann, Frederic A; Barco, Stefano; Spescha, Rebecca; Leeger, Claudia; Kucher, Nils (2019). Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome. Thrombosis and haemostasis, 119(12), pp. 2064-2073. Thieme 10.1055/s-0039-1697955

Seiler, Kristina

Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

Semmo, Nasser

Beyoğlu, Diren; Schwalm, Stephanie; Semmo, Nasser; Huwiler, Andrea; Idle, Jeffrey R (2023). Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021407

Seyed Jafari, Seyed Morteza

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Shibutani, Hiroki

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2023). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. (In Press). Thrombosis and haemostasis Thieme 10.1055/a-2156-7872

Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

Bär, Sarah; Kavaliauskaite, Raminta; Otsuka, Tatsuhiko; Ueki, Yasushi; Häner, Jonas D; Siontis, George C M; Stortecky, Stefan; Shibutani, Hiroki; Temperli, Fabrice; Kaiser, Christoph; Iglesias, Juan; Jan van Geuns, Robert; Daemen, Joost; Spirk, David; Engstrøm, Thomas; Lang, Irene; Windecker, Stephan; Koskinas, Konstantinos C; Losdat, Sylvain and Räber, Lorenz (2023). Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention, 19(4), e286-e296. Europa Digital & Publishing 10.4244/EIJ-D-23-00201

Sidler, Daniel

Kueng, Nicholas; Sidler, Daniel; Banz, Vanessa; Largiadèr, Carlo R; Ng, Charlotte K Y; Amstutz, Ursula (2023). Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis. Diagnostics, 13(15) MDPI 10.3390/diagnostics13152505

Siegrist, Mark

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Sigel, Erwin

Sigel, E; Baur, R; Boulineau, N; Minier, F (2006). Impact of subunit positioning on GABAA receptor function. Biochemical Society transactions, 34(Pt 5), pp. 868-71. London: Portland Press

Baur, Roland; Minier, Frédéric; Sigel, Erwin (2006). A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits. FEBS letters, 580(6), pp. 1616-20. Amsterdam: Elsevier 10.1016/j.febslet.2006.02.002

Peter, Andreas B.; Schittny, Johannes C.; Niggli, Verena; Reuter, Harald; Sigel, Erwin (1991). The polarized distribution of poly(A+)-mRNA-induced functional ion channels in the Xenopus oocyte plasma membrane is prevented by anticytoskeletal drugs. Journal of cell biology, 114(3), pp. 455-464. Rockefeller Institute Press

Silbernagel, Günther

Silbernagel, Günther; Spirk, David; Hager, Adrian; Baumgartner, Iris; Kucher, Nils (2016). Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial. Journal of the American Heart Association, 5(7), pp. 1-7. American Heart Association 10.1161/JAHA.116.003776

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Haas, Quentin; Simillion, Cedric André Marie; von Gunten, Stephan (2018). A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future? Frontiers in oncology, 8, p. 68. Frontiers Research Foundation 10.3389/fonc.2018.00068

Simon, Dagmar

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. (In Press). Clinical and translational gastroenterology Wolters Kluwer Health 10.14309/ctg.0000000000000664

Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

Heil, Alexis; Kuehlewindt, Tobias; Godat, Anne; Simon, Hans-Uwe; Simon, Dagmar; Schreiner, Philipp; Saner, Catherine; Vavricka, Stephan R; Biedermann, Luc; Safroneeva, Ekaterina; Rossel, Jean-Benoît; Limacher, Andreas; Straumann, Alex; Schoepfer, Alain M; Greuter, Thomas (2024). Histological Phenotyping in Eosinophilic Esophagitis: Localized Proximal Disease Is Infrequent but Associated with Less Severe Disease and Better Disease Outcome. International archives of allergy and immunology, 185(1), pp. 63-72. Karger 10.1159/000533815

Jesenak, Milos; Diamant, Zuzana; Simon, Dagmar; Tufvesson, Ellen; Seys, Sven F; Mukherjee, Manali; Lacy, Paige; Vijverberg, Susanne; Slisz, Tomas; Sediva, Anna; Simon, Hans-Uwe; Striz, Ilja; Plevkova, Jana; Schwarze, Jurgen; Kosturiak, Radovan; Alexis, Neil E; Untersmayr, Eva; Vasakova, Martina Koziar; Knol, Edward and Koenderman, Leo (2023). Eosinophils-from cradle to grave: An EAACI task force paper on new molecular insights and clinical functions of eosinophils and the clinical effects of targeted eosinophil depletion. Allergy, 78(12), pp. 3077-3102. Wiley 10.1111/all.15884

Gigon, Lea; Fettrelet, Timothée; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2023). Eosinophils from A to Z. Allergy, 78(7), pp. 1810-1846. Wiley 10.1111/all.15751

Valent, Peter; Klion, Amy D; Roufosse, Florence; Simon, Dagmar; Metzgeroth, Georgia; Leiferman, Kristin M; Schwaab, Juliana; Butterfield, Joseph H; Sperr, Wolfgang R; Sotlar, Karl; Vandenberghe, Peter; Hoermann, Gregor; Haferlach, Torsten; Moriggl, Richard; George, Tracy I; Akin, Cem; Bochner, Bruce S; Gotlib, Jason; Reiter, Andreas; Horny, Hans-Peter; ... (2023). Proposed Refined Diagnostic Criteria and Classification of Eosinophil Disorders and Related Syndromes. Allergy, 78(1), pp. 47-59. Wiley 10.1111/all.15544

Bürgler, Christina; Dutoit, Danielle; Radonjic-Hoesli, Susanne; Thormann, Kathrin; Lehmann, Mathias; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2023). Dupilumab normalizes correlates of lysosomal function in atopic dermatitis (In Press). JEADV Clinical Practice Wiley 10.1002/jvc2.307

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. Allergy, 77(8), pp. 2520-2533. Wiley 10.1111/all.15233

Radonjic-Hoesli, Susanne; Pavlov, Nikolay; Simon, Hans-Uwe; Simon, Dagmar (2022). Are blood cytokines reliable biomarkers of allergic disease diagnosis and treatment responses? Journal of allergy and clinical immunology, 150(2), pp. 251-258. Elsevier 10.1016/j.jaci.2022.06.008

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Klapan, Kim; Simon, Dagmar; Karaulov, Alexander; Gomzikova, Marina; Rizvanov, Albert; Yousefi, Shida; Simon, Hans-Uwe (2022). Autophagy and Skin Diseases. Frontiers in Pharmacology, 13, p. 844756. Frontiers 10.3389/fphar.2022.844756

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Radonjic-Hoesli, Susanne; Brüggen, Marie-Charlotte; Feldmeyer, Laurence; Simon, Hans-Uwe; Simon, Dagmar (2021). Eosinophils in skin diseases. Seminars in immunopathology, 43(3), pp. 393-409. Springer 10.1007/s00281-021-00868-7

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Biedermann, Luc; Holbreich, Mark; Atkins, Dan; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Hirano, Ikuo; Gonsalves, Nirmala; Greuter, Thomas; Katzka, David A; De Rooij, Willemijn; Safroneeva, Ekaterina; Schoepfer, Alain; Schreiner, Philipp; Simon, Dagmar; Simon, Hans Uwe; Warners, Marijn; Bredenoord, Albert-Jan; Straumann, Alex (2021). Food-induced Immediate Response of the Esophagus - a newly identified Syndrome in Patients with Eosinophilic Esophagitis. Allergy, 76(1), pp. 339-347. Wiley-Blackwell 10.1111/all.14495

Holvoet, Sébastien; Nutten, Sophie; Dupuis, Lénaïck; Donnicola, Dominique; Bourdeau, Tristan; Hughes-Formella, Betsy; Simon, Dagmar; Simon, Hans-Uwe; Carvalho, Ryan S.; Spergel, Jonathan M.; Koletzko, Sibylle; Blanchard, Carine (2021). Partially Hydrolysed Whey-Based Infant Formula Improves Skin Barrier Function. Nutrients, 13(9), p. 3113. Molecular Diversity Preservation International MDPI 10.3390/nu13093113

Schreiner, Philipp; Meissgeier, Silas; Safroneeva, Ekaterina; Greuter, Thomas; Rogler, Gerhard; Schoepfer, Alain; Simon, Dagmar; Simon, Hans-Uwe; Biedermann, Luc; Straumann, Alex (2020). Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology, 18(11), pp. 2456-2462. Elsevier 10.1016/j.cgh.2019.11.057

Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Maurer, Marcus; Eyerich, Kilian; Eyerich, Stefanie; Ferrer, Marta; Gutermuth, Jan; Hartmann, Karin; Jakob, Thilo; Kapp, Alexander; Kolkhir, Pavel; Larenas-Linnemann, Désirée; Park, Hae-Sim; Pejler, Gunnar; Sánchez-Borges, Mario; Schäkel, Knut; Simon, Dagmar; Simon, Hans-Uwe; Weller, Karsten; Zuberbier, Torsten; Metz, Martin (2020). Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(5), pp. 321-333. Karger 10.1159/000507218

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Simon, Dagmar; Simon, Hans-Uwe (2020). Relationship of skin barrier breakdown and eosinophilic esophagitis. Journal of allergy and clinical immunology, 145(1), 90-92.e1. Elsevier 10.1016/j.jaci.2019.11.005

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Karra, Laila; Gangwar, Roopesh Singh; Puzzovio, Pier Giorgio; Fyhrquist, Nanna; Minai-Fleminger, Yael; Landolina, Nadine; Simon, Hans-Uwe; Alenius, Harri; Leibovici, Vera; Simon, Dagmar; Levi-Schaffer, Francesca (2019). CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response. Allergy, 74(7), pp. 1377-1380. Wiley 10.1111/all.13724

Simon, Dagmar; Simon, Hans-Uwe (2019). Therapeutic strategies for eosinophilic dermatoses. Current opinion in pharmacology, 46, pp. 29-33. Elsevier 10.1016/j.coph.2019.01.002

Simon, Dagmar; Wollenberg, Andreas; Renz, Harald; Simon, Hans-Uwe (2019). Atopic Dermatitis: Collegium Internationale Allergologicum (CIA) Update 2019. International archives of allergy and immunology, 178(3), pp. 207-218. Karger 10.1159/000497383

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Simon, Dagmar; Simon, Hans-Uwe (2019). The role of pharmacists (In Press). In: Brockow, Brockow; Mortz, Charlotte (eds.) Global atlas of skin allergy (pp. 276-278). European academy of allergy and clinical immunology

Sauser, Julien; Nutten, Sophie; de Groot, Nanda; Pecquet, Sophie; Simon, Dagmar; Simon, Hans-Uwe; Spergel, Jonathan M; Koletzko, Sibylle; Blanchard, Carine (2018). Partially Hydrolyzed Whey Infant Formula: Literature Review on Effects on Growth and the Risk of Developing Atopic Dermatitis in Infants from the General Population. International archives of allergy and immunology, 177(2), pp. 123-134. Karger 10.1159/000489861

Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J; Arron, Joseph R; Bochner, Bruce S; Collins, Margaret H; Kahn, Jean-Emmanuel; Fulkerson, Patricia C; Gleich, Gerald J; Gopal-Srivastava, Rashmi; Jacobsen, Elizabeth A; Leiferman, Kristen M; Francesca, Levi-Schaffer; Mathur, Sameer K; Minnicozzi, Michael; Prussin, Calman; Rothenberg, Marc E; Roufosse, Florence; Sable, Kathleen; Simon, Dagmar; ... (2018). Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of leukocyte biology, 104(1), pp. 69-83. Society for Leukocyte Biology 10.1002/JLB.5MR0118-028R

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493

Simon, Dagmar; Page, Basile; Vogel, Monique; Bussmann, Christian; Blanchard, Carine; Straumann, Alex; Simon, Hans-Uwe (2018). Evidence of an abnormal epithelial barrier in active, untreated and corticosteroid-treated eosinophilic esophagitis. Allergy, 73(1), pp. 239-247. Wiley-Blackwell 10.1111/all.13244

Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

Blanchard, C.; Simon, Dagmar; Schoepfer, A.; Straumann, A.; Simon, Hans-Uwe (2017). Eosinophilic esophagitis: unclear roles of IgE and eosinophils. Journal of internal medicine, 281(5), pp. 448-457. Blackwell Scientific Publications 10.1111/joim.12568

Simon, Dagmar; Straumann, Alex; Schoepfer, Alain M; Simon, Hans-Uwe (2017). Current concepts in eosinophilic esophagitis. Allergo journal international, 26(7), pp. 258-266. Springer 10.1007/s40629-017-0037-8

Bieber, T; Akdis, C; Lauener, R; Traidl-Hoffmann, C; Schmid-Grendelmeier, P; Schäppi, G; Allam, J-P; Apfelbacher, C; Augustin, M; Beck, L; Biedermann, T; Braun-Fahrländer, C; Chew, F T; Clavel, T; Crameri, R; Darsow, U; Deleuran, M; Dittlein, D; Duchna, H-W; Eichenfeld, L; ... (2016). Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine. Allergy, 71(5), pp. 588-592. Wiley-Blackwell 10.1111/all.12857

Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879

Simon, Dagmar; Cianferoni, A; Spergel, J M; Aceves, S; Holbreich, M; Venter, C; Rothenberg, M E; Terreehorst, I; Muraro, A; Lucendo, A J; Schoepfer, A; Straumann, A; Simon, Hans-Uwe (2016). Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity. Allergy, 71(5), pp. 611-620. Wiley-Blackwell 10.1111/all.12846

Simon, Hans-Uwe; Simon, Dagmar (2016). Leserbrief zum Beitrag Hypereosinophilie. Swiss medical weekly, 16(4), p. 104. EMH Schweizerischer Ärzteverlag

Simon, Hans-Uwe; Yousefi, Shida; Simon, Dagmar (2016). Basophils can form extracellular DNA traps independent of a functional NADPH oxidase. In: Maurer, Markus; Behrendt, Heidrum (eds.) Allergies: Current challenges and solutions. Proceedings of the 30th Symposium of the Collegium Internationale Allergologicum (CIA) (pp. 67-70). Ospedaletto (Pisa): Pacini editore Medicina

Schorer, Myriam Fabiola; Simon, Dagmar (2016). Innate immune system crosstalk: Eosinophils mediate immune modulation of dendritic cells through exosomes as shuttle vectors of miRNA (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Simon, Dagmar; Straumann, A.; Simon, Hans-Uwe (2014). Eosinophilic esophagitis and allergy. Digestive diseases, 32(1-2), pp. 30-33. Karger 10.1159/000357006

Simon, D.; Aeberhard, C.; Erdemoglu, Y.; Simon, H.-U. (2014). Th17 cells and tissue remodeling in atopic and contact dermatitis. Allergy, 69(1), pp. 125-131. Wiley-Blackwell 10.1111/all.12351

Houriet, C.; Simon, H.-U.; Simon, D. (2014). Hypereosinophilic Syndromes. Aktuelle Dermatologie, 40(4), pp. 127-132. Thieme 10.1055/s-0034-1365078

Ring, J.; Akdis, C.; Lauener, R.; Schäppi, G.; Traidl-Hoffmann, C.; Akdis, M.; Ammann, W.; Behrendt, H.; Bieber, T.; Biedermann, T.; Bienenstock, J.; Blaser, K.; Braun-Fahrländer, C.; Brocknow, K.; Buters, J.; Crameri, R.; Darsow, U.; Denburg, J.A.; Eyerich, K.; Frei, R.; ... (2014). Global Allergy Forum and Second Davos Declaration 2013 Allergy: Barriers to cure - challenges and actions to be taken. Allergy, 69(8), pp. 978-982. Wiley-Blackwell 10.1111/all.12406

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2013). Glucocorticoids in autoimmune bullous diseases: are neutrophils the key cellular target? Journal of Investigative Dermatology, 133(10), pp. 2314-2315. Nature Publishing 10.1038/jid.2013.205

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2013). Extracellular DNA traps in allergic, infectzious, and autoimmune diseases. Allergy, 68(4), pp. 409-416. Wiley-Blackwell 10.1111/all.12111

Simon, D.; Straumann, A.; Dahinden, C.; Simon, H.-U. (2013). Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis. Allergy, 68(7), pp. 945-948. Wiley-Blackwell 10.1111/all.12157

Simon, Dagmar; Simon, Hans-Uwe (2013). Eosinophilic skin diseases. In: Lee, James J.; Rosenberg, Helene F. (eds.) Eosinophils in health and diseases (pp. 442-448). Amsterdam: Elsevier

von Gunten, S; Marsland, B J; von Garnier, C; Simon, D (2012). Update in clinical allergy and immunology. Allergy, 67(12), pp. 1491-500. Oxford: Wiley-Blackwell 10.1111/all.12067

Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2012). Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease. Current opinion in immunology, 24(6), pp. 736-9. Kidlington, UK: Elsevier 10.1016/j.coi.2012.08.010

Wechsler, Michael E; Fulkerson, Patricia C; Bochner, Bruce S; Gauvreau, Gail M; Gleich, Gerald J; Henkel, Tim; Kolbeck, Roland; Mathur, Sameer K; Ortega, Hector; Patel, Jatin; Prussin, Calman; Renzi, Paolo; Rothenberg, Marc E; Roufosse, Florence; Simon, Dagmar; Simon, Hans-Uwe; Wardlaw, Andrew; Weller, Peter F; Klion, Amy D (2012). Novel targeted therapies for eosinophilic disorders. Journal of allergy and clinical immunology, 130(3), pp. 563-71. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.07.027

Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x

Simon, Dagmar; Simon, Hans-Uwe (2012). New drug targets in atopic dermatitis. Chemical immunology and allergy, 96, pp. 126-131. Basel: Karger

Straumann, A; Aceves, S S; Blanchard, C; Collins, M H; Furuta, G T; Hirano, I; Schoepfer, A M; Simon, D; Simon, H-U (2012). Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy, 67(4), pp. 477-90. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02787.x

Roth, N; Städler, S; Lemann, M; Hösli, S; Simon, H-U; Simon, D (2011). Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. Allergy, 66(11), pp. 1477-86. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02694.x

Simon, Dagmar; Hoesli, Susanne; Roth, Nina; Staedler, Simon; Yousefi, Shida; Simon, Hans-Uwe (2011). Eosinophil extracellular DNA traps in skin diseases. Journal of allergy and clinical immunology, 127(1), pp. 194-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.11.002

Salemi, S; Yousefi, S; Simon, D; Schmid, I; Moretti, L; Scapozza, L; Simon, H-U (2009). A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. Allergy, 64(6), pp. 913-8. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.01943.x

Ogbogu, Princess U; Bochner, Bruce S; Butterfield, Joseph H; Gleich, Gerald J; Huss-Marp, Johannes; Kahn, Jean Emmanuel; Leiferman, Kristin M; Nutman, Thomas B; Pfab, Florian; Ring, Johannes; Rothenberg, Marc E; Roufosse, Florence; Sajous, Marie-Helene; Sheikh, Javed; Simon, Dagmar; Simon, Hans-Uwe; Stein, Miguel L; Wardlaw, Andrew; Weller, Peter F and Klion, Amy D (2009). Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. Journal of allergy and clinical immunology, 124(6), 1319-25.e3. St. Louis, Mo.: Mosby 10.1016/j.jaci.2009.09.022

Simon, Dagmar; Salemi, Souzan; Yousefi, Shida; Simon, Hans-Uwe (2008). Primary resistance to imatinib in Fip1-like 1-platelet-derived growth factor receptor alpha-positive eosinophilic leukemia. Journal of allergy and clinical immunology, 121(4), pp. 1054-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.027

Kostylina, G; Simon, D; Fey, M F; Yousefi, S; Simon, H U (2008). Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A). Cell death and differentiation, 15(1), pp. 134-42. Basingstoke: Nature Publishing Group 10.1038/sj.cdd.4402238

Simon, Dagmar; Wittwer, Jennifer; Kostylina, Ganna; Buettiker, Urs; Simon, Hans-Uwe; Yawalkar, Nikhil (2008). Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema. Journal of allergy and clinical immunology, 122(2), pp. 423-4. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.010

Simon, Dagmar; Hösli, Susanne; Kostylina, Ganna; Yawalkar, Nikhil; Simon, Hans-Uwe (2008). Anti-CD20 (rituximab) treatment improves atopic eczema. Journal of allergy and clinical immunology, 121(1), pp. 122-8. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.016

Hassan, Akmal S; Simon, Dagmar; Simon, Hans-Uwe; Braathen, Lasse R; Yawalkar, Nikhil (2007). Efalizumab-associated papular psoriasis. Archives of dermatology, 143(7), pp. 900-6. Chicago, Ill.: American Medical Association 10.1001/archderm.143.7.900

Simon, D; Braathen, L R; Simon, H-U (2007). Increased lipopolysaccharide-induced tumour necrosis factor-alpha, interferon-gamma and interleukin-10 production in atopic dermatitis. British journal of dermatology, 157(3), pp. 583-6. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2007.08050.x

Simon, Dagmar; Simon, Hans-Uwe (2007). Eosinophilic disorders. Journal of allergy and clinical immunology, 119(6), 1291-300; quiz 1301-2. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.02.010

Simon, D; Braathen, L R; Simon, H-U (2007). [Anti-interleukin-5 therapy for eosinophilic diseases]. Hautarzt, 58(2), 122, 124-7. Heidelberg: Springer-Verlag 10.1007/s00105-006-1273-x

Vassina, Ekatherina M; Yousefi, Shida; Simon, Dagmar; Zwicky, Caroline; Conus, Sébastien; Simon, Hans-Uwe (2006). cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. European journal of immunology, 36(7), pp. 1975-84. Weinheim: Wiley-VCH 10.1002/eji.200635943

Simon, D; Straumann, A; Wenk, A; Spichtin, H; Simon, H-U; Braathen, L R (2006). Eosinophilic esophagitis in adults--no clinical relevance of wheat and rye sensitizations. Allergy, 61(12), pp. 1480-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01224.x

Simon, Dagmar; Lindberg, Raija L P; Kozlowski, Evelyne; Braathen, Lasse R; Simon, Hans-Uwe (2006). Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions. Experimental dermatology, 15(6), pp. 441-6. Oxford: Blackwell 10.1111/j.0906-6705.2006.00428.x

Baumann, Ralf; Yousefi, Shida; Simon, Dagmar; Russmann, Stefan; Mueller, Christoph; Simon, Hans-Uwe (2004). Functional expression of CD134 by neutrophils. European journal of immunology, 34(8), pp. 2268-2275. Wiley-VCH 10.1002/eji.200424863

Simon, Hans-Uwe

Chen, Xin; Tsvetkov, Andrey S; Shen, Han-Ming; Isidoro, Ciro; Ktistakis, Nicholas T; Linkermann, Andreas; Koopman, Werner J H; Simon, Hans-Uwe; Galluzzi, Lorenzo; Luo, Shouqing; Xu, Daqian; Gu, Wei; Peulen, Olivier; Cai, Qian; Rubinsztein, David C; Chi, Jen-Tsan; Zhang, Donna D; Li, Changfeng; Toyokuni, Shinya; Liu, Jinbao; ... (2024). International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis. (In Press). Autophagy, pp. 1-34. Taylor & Francis 10.1080/15548627.2024.2319901

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. (In Press). Clinical and translational gastroenterology Wolters Kluwer Health 10.14309/ctg.0000000000000664

Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2024). NETs: Important players in asthma? Journal of allergy and clinical immunology, 153(1), pp. 100-102. Elsevier 10.1016/j.jaci.2023.09.031

Heil, Alexis; Kuehlewindt, Tobias; Godat, Anne; Simon, Hans-Uwe; Simon, Dagmar; Schreiner, Philipp; Saner, Catherine; Vavricka, Stephan R; Biedermann, Luc; Safroneeva, Ekaterina; Rossel, Jean-Benoît; Limacher, Andreas; Straumann, Alex; Schoepfer, Alain M; Greuter, Thomas (2024). Histological Phenotyping in Eosinophilic Esophagitis: Localized Proximal Disease Is Infrequent but Associated with Less Severe Disease and Better Disease Outcome. International archives of allergy and immunology, 185(1), pp. 63-72. Karger 10.1159/000533815

Jesenak, Milos; Diamant, Zuzana; Simon, Dagmar; Tufvesson, Ellen; Seys, Sven F; Mukherjee, Manali; Lacy, Paige; Vijverberg, Susanne; Slisz, Tomas; Sediva, Anna; Simon, Hans-Uwe; Striz, Ilja; Plevkova, Jana; Schwarze, Jurgen; Kosturiak, Radovan; Alexis, Neil E; Untersmayr, Eva; Vasakova, Martina Koziar; Knol, Edward and Koenderman, Leo (2023). Eosinophils-from cradle to grave: An EAACI task force paper on new molecular insights and clinical functions of eosinophils and the clinical effects of targeted eosinophil depletion. Allergy, 78(12), pp. 3077-3102. Wiley 10.1111/all.15884

Shuvalov, Oleg; Kirdeeva, Yulia; Daks, Alexandra; Fedorova, Olga; Parfenyev, Sergey; Simon, Hans-Uwe; Barlev, Nickolai A (2023). Phytochemicals Target Multiple Metabolic Pathways in Cancer. Antioxidants, 12(11) MDPI 10.3390/antiox12112012

Brichkina, Anna; Simon, Hans-Uwe (2023). A novel role for mitochondrial fission in macrophages: trained innate immunity induced by beta-glucan. Cellular & molecular immunology, 20(8), pp. 864-866. Springer Nature 10.1038/s41423-023-01017-w

Gigon, Lea; Fettrelet, Timothée; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2023). Eosinophils from A to Z. Allergy, 78(7), pp. 1810-1846. Wiley 10.1111/all.15751

Vitale, Ilio; Pietrocola, Federico; Guilbaud, Emma; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostini, Massimiliano; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Aqeilan, Rami I; Arama, Eli; Baehrecke, Eric H; Balachandran, Siddharth; Bano, Daniele; Barlev, Nickolai A; Bartek, Jiri; Bazan, Nicolas G; ... (2023). Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell death and differentiation, 30(5), pp. 1097-1154. Nature Publishing Group 10.1038/s41418-023-01153-w

Peng, Shuang; Gao, Jian; Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2023). Established and emerging roles for mitochondria in neutrophils. Immunological reviews, 314(1), pp. 413-426. Wiley-Blackwell 10.1111/imr.13158

Simon, Hans-Uwe (2023). Legends of Allergology and Immunology: Alex Straumann. Allergy, 78(2), pp. 596-598. Wiley-Blackwell 10.1111/all.15520

Hosseini, Aref; Stojkov, Darko; Fettrelet, Timothée; Bilyy, Rostyslav; Yousefi, Shida; Simon, Hans-Uwe (2023). Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032646

Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517

Kaufmann, Thomas; Simon, Hans-Uwe (2023). Pharmacological Induction of Granulocyte Cell Death As Therapeutic Strategy. Annual review of pharmacology and toxicology, 63, pp. 231-247. Annual Reviews Inc. 10.1146/annurev-pharmtox-051921-115130

Valent, Peter; Klion, Amy D; Roufosse, Florence; Simon, Dagmar; Metzgeroth, Georgia; Leiferman, Kristin M; Schwaab, Juliana; Butterfield, Joseph H; Sperr, Wolfgang R; Sotlar, Karl; Vandenberghe, Peter; Hoermann, Gregor; Haferlach, Torsten; Moriggl, Richard; George, Tracy I; Akin, Cem; Bochner, Bruce S; Gotlib, Jason; Reiter, Andreas; Horny, Hans-Peter; ... (2023). Proposed Refined Diagnostic Criteria and Classification of Eosinophil Disorders and Related Syndromes. Allergy, 78(1), pp. 47-59. Wiley 10.1111/all.15544

Idrisova, K. F.; Simon, H.-U.; Gomzikova, M. O. (2023). Role of Patient-Derived Models of Cancer in Translational Oncology. Cancers, 15(1), p. 139. MDPI AG 10.3390/cancers15010139

Daks, Alexandra; Shuvalov, Oleg; Fedorova, Olga; Parfenyev, Sergey; Simon, Hans-Uwe; Barlev, Nickolai A (2023). Methyltransferase Set7/9 as a Multifaceted Regulator of ROS Response. International journal of biological sciences, 19(8), pp. 2304-2318. 10.7150/ijbs.83158

Gigon, Lea; Fettrelet, Timothée; Miholic, Marta; McLeish, Kenneth R; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2023). Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. Frontiers in immunology, 14(1272699), p. 1272699. Frontiers Research Foundation 10.3389/fimmu.2023.1272699

Bürgler, Christina; Dutoit, Danielle; Radonjic-Hoesli, Susanne; Thormann, Kathrin; Lehmann, Mathias; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2023). Dupilumab normalizes correlates of lysosomal function in atopic dermatitis (In Press). JEADV Clinical Practice Wiley 10.1002/jvc2.307

Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14 Frontiers Research Foundation 10.3389/fimmu.2023.1331151

Mucke, Johanna; Simon, Hans-Uwe; Burmester, Gerd Rüdiger (2022). The Safety of Antirheumatic Drugs. Deutsches Ärzteblatt international, 119(6), pp. 81-87. Deutscher Ärzte-Verlag 10.3238/arztebl.m2022.0064

Peng, Shuang; Stojkov, Darko; Gao, Jian; Oberson, Kevin; Latzin, Philipp; Casaulta, Carmen; Yousefi, Shida; Simon, Hans-Uwe (2022). Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils. PLoS biology, 20(9), e3001794. Public Library of Science 10.1371/journal.pbio.3001794

Mucke, Johanna; Simon, Hans-Uwe; Burmester, Gerd Rüdiger (2022). In Reply. Deutsches Ärzteblatt international, 119(33-34), p. 567. Deutscher Ärzte-Verlag 10.3238/arztebl.m2022.0186

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. Allergy, 77(8), pp. 2520-2533. Wiley 10.1111/all.15233

Radonjic-Hoesli, Susanne; Pavlov, Nikolay; Simon, Hans-Uwe; Simon, Dagmar (2022). Are blood cytokines reliable biomarkers of allergic disease diagnosis and treatment responses? Journal of allergy and clinical immunology, 150(2), pp. 251-258. Elsevier 10.1016/j.jaci.2022.06.008

Radonjic-Hoesli, Susanne; Martignoni, Zora; Cazzaniga, Simone; Furrer, Dominique Isabel; Simon, Hans-Uwe; Bürgler, Christina; Simon, Dagmar (2022). Characteristics of dermatological patients with blood eosinophilia: a retrospective analysis of 453 patients. The journal of allergy and clinical immunology. In practice, 10(5), 1229-1237.e8. Elsevier 10.1016/j.jaip.2022.02.018

Bon, Lorenz; Safroneeva, Ekaterina; Bussmann, Christian; Biedermann, Luc; Schreiner, Philipp; Vavricka, Stephan R; Schoepfer, Alain M; McCright-Gill, Talaya; Simon, Hans-Uwe; Straumann, Alex; Chehade, Mirna; Greuter, Thomas (2022). Close follow-up is associated with fewer stricture formation and results in earlier detection of histological relapse in the long-term management of eosinophilic esophagitis. United European gastroenterology journal, 10(3), pp. 308-318. Wiley 10.1002/ueg2.12216

Fallegger, Angela; Priola, Martina; Artola-Borán, Mariela; Núñez, Nicolás Gonzalo; Wild, Sebastian; Gurtner, Alessandra; Becher, Burkhard; Yousefi, Shida; Simon, Hans-Uwe; Arnold, Isabelle C; Müller, Anne (2022). TGF-β production by eosinophils drives the expansion of peripherally induced neuropilin- RORγt+ regulatory T-cells during bacterial and allergen challenge. Mucosal immunology, 15(3), pp. 504-514. Springer Nature 10.1038/s41385-022-00484-0

Klapan, Kim; Simon, Dagmar; Karaulov, Alexander; Gomzikova, Marina; Rizvanov, Albert; Yousefi, Shida; Simon, Hans-Uwe (2022). Autophagy and Skin Diseases. Frontiers in Pharmacology, 13, p. 844756. Frontiers 10.3389/fphar.2022.844756

Artola-Borán, Mariela; Fallegger, Angela; Priola, Martina; Jeske, Rima; Waterboer, Tim; Dohlman, Anders B; Shen, Xiling; Wild, Sebastian; He, Jiazhuo; Levesque, Mitchell P; Yousefi, Shida; Simon, Hans-Uwe; Cheng, Phil F; Müller, Anne (2022). Mycobacterial infection aggravates Helicobacter pylori-induced gastric preneoplastic pathology by redirection of de novo induced Treg cells. Cell reports, 38(6), p. 110359. Cell Press 10.1016/j.celrep.2022.110359

Cristinziano, Leonardo; Modestino, Luca; Antonelli, Alessandro; Marone, Gianni; Simon, Hans-Uwe; Varricchi, Gilda; Galdiero, Maria Rosaria (2022). Neutrophil extracellular traps in cancer. Seminars in cancer biology, 79, pp. 91-104. Elsevier 10.1016/j.semcancer.2021.07.011

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Schoepfer, Alain M; Henchoz, Sarah; Biedermann, Luc; Schreiner, Philipp; Greuter, Thomas; Reinhard, Antoine; Senn, Jonduri; Franke, Annett; Burri, Emanuel; Juillerat, Pascal; Simon, Hans-Uwe; Straumann, Alex; Safroneeva, Ekaterina; Godat, Sébastien (2021). Technical feasibility, clinical effectiveness, and safety of esophageal stricture dilation using a novel endoscopic attachment cap in adults with eosinophilic esophagitis. Gastrointestinal endoscopy, 94(5), 912-919.e2. Elsevier 10.1016/j.gie.2021.05.017

Ackermann, Maximilian; Anders, Hans-Joachim; Bilyy, Rostyslav; Bowlin, Gary L; Daniel, Christoph; De Lorenzo, Rebecca; Egeblad, Mikala; Henneck, Timo; Hidalgo, Andrés; Hoffmann, Markus; Hohberger, Bettina; Kanthi, Yogendra; Kaplan, Mariana J; Knight, Jason S; Knopf, Jasmin; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; Mahajan, Aparna; Manfredi, Angelo A; ... (2021). Patients with COVID-19: in the dark-NETs of neutrophils. Cell death and differentiation, 28(11), pp. 3125-3139. Springer Nature 10.1038/s41418-021-00805-z

Klionsky, Daniel J; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M K; Choi, Mary E; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; ... (2021). Autophagy in major human diseases. The EMBO journal, 40(19), e108863. EMBO Press 10.15252/embj.2021108863

Delemarre, Tim; Bochner, Bruce S; Simon, Hans-Uwe; Bachert, Claus (2021). Rethinking neutrophils and eosinophils in chronic rhinosinusitis. Journal of allergy and clinical immunology, 148(2), pp. 327-335. Elsevier 10.1016/j.jaci.2021.03.024

Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Renz, Harald; Bachert, Claus; Berek, Claudia; Hamelmann, Eckard; Levi-Schaffer, Francesca; Raap, Ulrike; Simon, Hans-Uwe; Ploetz, Sabine; Taube, Christian; Valent, Peter; Voehringer, David; Werfel, Thomas; Zhang, Nan; Ring, Johannes (2021). Physiology and pathology of eosinophils: Recent developments: Summary of the Focus Workshop Organized by DGAKI. Scandinavian journal of immunology, 93(6), e13032. Wiley-Blackwell 10.1111/sji.13032

Radonjic-Hoesli, Susanne; Brüggen, Marie-Charlotte; Feldmeyer, Laurence; Simon, Hans-Uwe; Simon, Dagmar (2021). Eosinophils in skin diseases. Seminars in immunopathology, 43(3), pp. 393-409. Springer 10.1007/s00281-021-00868-7

Simon, Hans-Uwe (2021). The eosinophil and its role in physiology and disease: news and views. Seminars in immunopathology, 43(3), pp. 291-293. Springer 10.1007/s00281-021-00866-9

Valent, Peter; Degenfeld-Schonburg, Lina; Sadovnik, Irina; Horny, Hans-Peter; Arock, Michel; Simon, Hans-Uwe; Reiter, Andreas; Bochner, Bruce S (2021). Eosinophils and eosinophil-associated disorders: immunological, clinical, and molecular complexity. Seminars in immunopathology, 43(3), pp. 423-438. Springer 10.1007/s00281-021-00863-y

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Biedermann, Luc; Holbreich, Mark; Atkins, Dan; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Hirano, Ikuo; Gonsalves, Nirmala; Greuter, Thomas; Katzka, David A; De Rooij, Willemijn; Safroneeva, Ekaterina; Schoepfer, Alain; Schreiner, Philipp; Simon, Dagmar; Simon, Hans Uwe; Warners, Marijn; Bredenoord, Albert-Jan; Straumann, Alex (2021). Food-induced Immediate Response of the Esophagus - a newly identified Syndrome in Patients with Eosinophilic Esophagitis. Allergy, 76(1), pp. 339-347. Wiley-Blackwell 10.1111/all.14495

Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003

Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia; ... (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), pp. 1-382. Taylor & Francis 10.1080/15548627.2020.1797280

Wang, Xiaoliang; Avsec, Damjan; Obreza, Aleš; Yousefi, Shida; Mlinarič-Raščan, Irena; Simon, Hans-Uwe (2021). A Putative Serine Protease is Required to Initiate the RIPK3-MLKL-Mediated Necroptotic Death Pathway in Neutrophils. Frontiers in Pharmacology, 11, p. 614928. Frontiers 10.3389/fphar.2020.614928

Bruno, Andreina; Di Sano, Caterina; Simon, Hans-Uwe; Chanez, Pascal; Patti, Angelo Maria; Di Vincenzo, Serena; Dino, Paola; D'Esposito, Vittoria; Formisano, Pietro; Beguinot, Francesco; Pace, Elisabetta (2021). Leptin and TGF-β1 Downregulate PREP1 Expression in Human Adipose-Derived Mesenchymal Stem Cells and Mature Adipocytes. Frontiers in cell and developmental biology, 9, p. 700481. Frontiers 10.3389/fcell.2021.700481

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Holvoet, Sébastien; Nutten, Sophie; Dupuis, Lénaïck; Donnicola, Dominique; Bourdeau, Tristan; Hughes-Formella, Betsy; Simon, Dagmar; Simon, Hans-Uwe; Carvalho, Ryan S.; Spergel, Jonathan M.; Koletzko, Sibylle; Blanchard, Carine (2021). Partially Hydrolysed Whey-Based Infant Formula Improves Skin Barrier Function. Nutrients, 13(9), p. 3113. Molecular Diversity Preservation International MDPI 10.3390/nu13093113

von Gunten, Stephan; Simon, Hans-Uwe (2020). Linking glucocorticoid-induced osteoporosis to osteoimmunology. Cell death & disease, 11(12), p. 1026. Nature Publishing Group 10.1038/s41419-020-03250-x

Piacentini, Mauro; Shi, Yufang; Simon, Hans-Uwe (2020). 10 years of Cell Death & Disease. Cell death & disease, 11(12), p. 1064. Springer Nature 10.1038/s41419-020-03287-y

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Schreiner, Philipp; Meissgeier, Silas; Safroneeva, Ekaterina; Greuter, Thomas; Rogler, Gerhard; Schoepfer, Alain; Simon, Dagmar; Simon, Hans-Uwe; Biedermann, Luc; Straumann, Alex (2020). Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis. Clinical gastroenterology and hepatology, 18(11), pp. 2456-2462. Elsevier 10.1016/j.cgh.2019.11.057

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Frangez, Z; Jafari, S M Seyed; Hunger, R E; Simon, H-U (2020). Loss of Concurrent Regulation of the Expression of BIF-1, BAX, and Beclin-1 in Primary and Metastatic Melanoma. Biochemistry (Moscow), 85(10), pp. 1227-1234. Pleiades 10.1134/S0006297920100107

Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113

Simon, Hans-Uwe; Karaulov, Alexander V; Bachmann, Martin F. (2020). Strategies to Prevent SARS-CoV-2-Mediated Eosinophilic Disease in Association with COVID-19 Vaccination and Infection. International archives of allergy and immunology, 181(8), pp. 624-628. Karger 10.1159/000509368

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007

Maurer, Marcus; Eyerich, Kilian; Eyerich, Stefanie; Ferrer, Marta; Gutermuth, Jan; Hartmann, Karin; Jakob, Thilo; Kapp, Alexander; Kolkhir, Pavel; Larenas-Linnemann, Désirée; Park, Hae-Sim; Pejler, Gunnar; Sánchez-Borges, Mario; Schäkel, Knut; Simon, Dagmar; Simon, Hans-Uwe; Weller, Karsten; Zuberbier, Torsten; Metz, Martin (2020). Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(5), pp. 321-333. Karger 10.1159/000507218

Müller, Ines; Strozyk, Elwira; Schindler, Sebastian; Beissert, Stefan; Oo, Htoo Zarni; Sauter, Thomas; Lucarelli, Philippe; Raeth, Sebastian; Hausser, Angelika; Al Nakouzi, Nader; Fazli, Ladan; Gleave, Martin E; Liu, He; Simon, Hans-Uwe; Walczak, Henning; Green, Douglas R; Bartek, Jiri; Daugaard, Mads; Kulms, Dagmar (2020). Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28. Molecular cell, 77(5), 970-984.e7. Cell Press 10.1016/j.molcel.2019.12.023

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

He, Zhaoyue; Liu, He; Moch, Holger; Simon, Hans-Uwe (2020). Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Scientific reports, 10(1), p. 720. Springer Nature 10.1038/s41598-020-57670-y

Cazzaniga, Simone; Wiedmer, Christina; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Dagmar; Naldi, Luigi; Simon, Hans-Uwe; Hunger, Robert E.; Seyed Jafari, S. Morteza (2020). Association of Vascular Endothelial Growth Factor Subtypes with Melanoma Patients' Characteristics and Survival: A Semantic Connectivity Map Analysis. Acta dermato-venereologica, 100(1), adv00019. Forum for Nordic Dermato-Venereology 10.2340/00015555-3374

Simon, Dagmar; Simon, Hans-Uwe (2020). Relationship of skin barrier breakdown and eosinophilic esophagitis. Journal of allergy and clinical immunology, 145(1), 90-92.e1. Elsevier 10.1016/j.jaci.2019.11.005

Markov, Nikita; Simon, Hans-Uwe (2020). IL-37: A new player in the chronic rhinosinusitis arena. The Journal of allergy and clinical immunology, 145(1), pp. 105-107. Elsevier 10.1016/j.jaci.2019.10.018

Surmiak, Marcin; Gielicz, Anna; Stojkov, Darko; Szatanek, Rafał; Wawrzycka-Adamczyk, Katarzyna; Yousefi, Shida; Simon, Hans-Uwe; Sanak, Marek (2020). LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis. Journal of lipid research, 61(1), pp. 1-9. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M092072

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1

Karra, Laila; Gangwar, Roopesh Singh; Puzzovio, Pier Giorgio; Fyhrquist, Nanna; Minai-Fleminger, Yael; Landolina, Nadine; Simon, Hans-Uwe; Alenius, Harri; Leibovici, Vera; Simon, Dagmar; Levi-Schaffer, Francesca (2019). CD300a expression is modulated in atopic dermatitis and could influence the inflammatory response. Allergy, 74(7), pp. 1377-1380. Wiley 10.1111/all.13724

Bruno, Andreina; Di Sano, Caterina; Lorusso, Francesco; Dino, Paola; Russo, Domenica; Ballacchino, Antonella; Gallina, Salvatore; Modica, Domenico Michele; Chiappara, Giuseppina; Simon, Hans-Uwe; Pace, Elisabetta (2019). Notch-1 decreased expression contributes to leptin receptor downregulation in nasal epithelium from allergic turbinates. Biochimica et biophysica acta - molecular basis of disease, 1865(6), pp. 1642-1650. Elsevier 10.1016/j.bbadis.2019.03.016

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Simon, Dagmar; Simon, Hans-Uwe (2019). Therapeutic strategies for eosinophilic dermatoses. Current opinion in pharmacology, 46, pp. 29-33. Elsevier 10.1016/j.coph.2019.01.002

Sokollik, Christiane; Simon, Hans-Uwe (2019). [Eosinophilic granulocytes-Physiology and pathophysiology]. Zeitschrift für Rheumatologie, 78(4), pp. 306-312. Springer-Medizin-Verlag 10.1007/s00393-018-0574-7

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Yadav, Sandeep Kumar; Stojkov, Darko; Feigelson, Sara W; Roncato, Francesco; Simon, Hans-Uwe; Yousefi, Shida; Alon, Ronen (2019). Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration. Journal of leukocyte biology, 105(4), pp. 755-766. Society for Leukocyte Biology 10.1002/JLB.3A1118-437RR

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Simon, Dagmar; Wollenberg, Andreas; Renz, Harald; Simon, Hans-Uwe (2019). Atopic Dermatitis: Collegium Internationale Allergologicum (CIA) Update 2019. International archives of allergy and immunology, 178(3), pp. 207-218. Karger 10.1159/000497383

Mortezavi, Ashkan; Salemi, Souzan; Kranzbühler, Benedikt; Gross, Oliver; Sulser, Tullio; Simon, Hans-Uwe; Eberli, Daniel (2019). Inhibition of autophagy significantly increases the antitumor effect of Abiraterone in prostate cancer. World journal of urology, 37(2), pp. 351-358. Springer-Verlag 10.1007/s00345-018-2385-5

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 1-8. Hogrefe 10.1024/1661-8157/a003250

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 469-476. Hogrefe 10.1024/1661-8157/a003222

Simon, Dagmar; Simon, Hans-Uwe (2019). The role of pharmacists (In Press). In: Brockow, Brockow; Mortz, Charlotte (eds.) Global atlas of skin allergy (pp. 276-278). European academy of allergy and clinical immunology

Eberli, Daniel; Horst, Maya; Mortezavi, Ashkan; Andersson, Karl-Erik; Gobet, Rita; Sulser, Tullio; Simon, Hans-Uwe; Salemi, Souzan (2018). Increased autophagy contributes to impaired smooth muscle function in neurogenic lower urinary tract dysfunction. Neurourology and urodynamics, 37(8), pp. 2414-2424. Wiley-Liss 10.1002/nau.23705

Miethe, Sarah; Guarino, Maria; Alhamdan, Fahd; Simon, Hans-Uwe; Renz, Harald; Dufour, Jean-François; Potaczek, Daniel P; Garn, Holger (2018). Effects of obesity on asthma: immunometabolic links. Polish archives of internal medicine, 128(7-8), pp. 469-477. Medycyna Praktyczna, Kraków, Poland 10.20452/pamw.4304

Arnold, Isabelle C; Artola-Borán, Mariela; Tallón de Lara, Paulino; Kyburz, Andreas; Taube, Christian; Ottemann, Karen; van den Broek, Maries; Yousefi, Shida; Simon, Hans-Uwe; Müller, Anne (2018). Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. Journal of experimental medicine, 215(8), pp. 2055-2072. Rockefeller University Press 10.1084/jem.20172049

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Sauser, Julien; Nutten, Sophie; de Groot, Nanda; Pecquet, Sophie; Simon, Dagmar; Simon, Hans-Uwe; Spergel, Jonathan M; Koletzko, Sibylle; Blanchard, Carine (2018). Partially Hydrolyzed Whey Infant Formula: Literature Review on Effects on Growth and the Risk of Developing Atopic Dermatitis in Infants from the General Population. International archives of allergy and immunology, 177(2), pp. 123-134. Karger 10.1159/000489861

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J; Arron, Joseph R; Bochner, Bruce S; Collins, Margaret H; Kahn, Jean-Emmanuel; Fulkerson, Patricia C; Gleich, Gerald J; Gopal-Srivastava, Rashmi; Jacobsen, Elizabeth A; Leiferman, Kristen M; Francesca, Levi-Schaffer; Mathur, Sameer K; Minnicozzi, Michael; Prussin, Calman; Rothenberg, Marc E; Roufosse, Florence; Sable, Kathleen; Simon, Dagmar; ... (2018). Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD). Journal of leukocyte biology, 104(1), pp. 69-83. Society for Leukocyte Biology 10.1002/JLB.5MR0118-028R

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Prince Eladnani, Raja; Bologna, Luca; Manetti, Mirko; Melchiorre, Daniela; Rosa, Irene; Dewarrat, Natacha; Suardi, Silvia; Amini, Poorya; Fernández, José A; Burnier, Laurent; Quarroz, Claudia; Reina Caro, Maria Desiré; Matsumura, Yasuhiro; Kremer Hovinga, Johanna Anna; Griffin, John H; Simon, Hans-Uwe; Ibba-Manneschi, Lidia; Saller, François; Calzavarini, Sara and Angelillo, Anne (2018). Targeting anticoagulant protein S to improve hemostasis in hemophilia. Blood, 131(12), pp. 1360-1371. American Society of Hematology 10.1182/blood-2017-09-800326

Gevaert, Elien; Yousefi, Shida; Bachert, Claus; Simon, Hans-Uwe (2018). Reply. The Journal of allergy and clinical immunology, 141(3), pp. 1164-1165. Elsevier 10.1016/j.jaci.2017.05.048

Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493

Simon, Hans-Uwe; Bieber, Thomas (2018). Allergy - Committed to Progress in Allergy and Immunology. Allergy, 73(3), p. 527. Wiley-Blackwell 10.1111/all.13412

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V; Arama, Eli; Baehrecke, Eric H; Barlev, Nickolai A; Bazan, Nicolas G; Bernassola, Francesca; Bertrand, Mathieu J M; Bianchi, Katiuscia; Blagosklonny, Mikhail V; ... (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell death and differentiation, 25(3), pp. 486-541. Nature Publishing Group 10.1038/s41418-017-0012-4

Wang, Xiaoliang; Yousefi, Shida; Simon, Hans-Uwe (2018). Necroptosis and neutrophil-associated disorders. Cell death & disease, 9(2), p. 111. Nature Publishing Group 10.1038/s41419-017-0058-8

Simon, Hans-Uwe (2018). International Archives of Allergy and Immunology: A Commitment to Serving the Community Worldwide. International archives of allergy and immunology, 175(1-2), pp. 3-4. Karger 10.1159/000485942

Simon, Dagmar; Page, Basile; Vogel, Monique; Bussmann, Christian; Blanchard, Carine; Straumann, Alex; Simon, Hans-Uwe (2018). Evidence of an abnormal epithelial barrier in active, untreated and corticosteroid-treated eosinophilic esophagitis. Allergy, 73(1), pp. 239-247. Wiley-Blackwell 10.1111/all.13244

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.

Liu, He; He, Zhaoyue; Bode, Peter; Moch, Holger; Simon, Hans-Uwe (2018). Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Frontiers in oncology, 8(366), p. 366. Frontiers Research Foundation 10.3389/fonc.2018.00366

Seyed Jafari, S. Morteza; Wiedmer, Christina; Cazzaniga, Simone; Frangež, Živa; Shafighi, Maziar; Beltraminelli, Helmut; Weber, Benedikt; Simon, Hans-Uwe; Hunger, Robert E. (2018). Correlation of Vascular Endothelial Growth Factor subtypes and their receptors with melanoma progression: A next-generation Tissue Microarray (ngTMA) automated analysis. PLoS ONE, 13(11), e0207019. Public Library of Science 10.1371/journal.pone.0207019

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2017). Eosinophils as putative therapeutic targets in bullous pemphigoid. Experimental dermatology, 26(12), pp. 1187-1192. Blackwell 10.1111/exd.13416

Wahn, Ulrich; Matricardi, Paolo M; Bieber, Thomas; Bousquet, Jean; Grattan, Clive; Simon, Hans-Uwe; Muraro, Antonella; Agache, Ioana (2017). Food allergy in EAACI journals (2016). Pediatric allergy and immunology, 28(8), pp. 825-830. Wiley-Blackwell 10.1111/pai.12830

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

Sokollik, Christiane; Simon, Hans-Uwe (2017). Physiologie der eosinophilen Granulozyten. Therapeutische Umschau, 74(6), pp. 291-296. Hogrefe 10.1024/0040-5930/a000917

Galluzzi, Lorenzo; Baehrecke, Eric H; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel; Cecconi, Francesco; Choi, Augustine M; Chu, Charleen T; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Debnath, Jayanta; Deretic, Vojo; Dikic, Ivan; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Fulda, Simone; Gewirtz, David A; Green, Douglas R; Hansen, Malene; ... (2017). Molecular definitions of autophagy and related processes. The EMBO Journal, 36(13), pp. 1811-1836. EMBO Press 10.15252/embj.201796697

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Muraro, Antonella; Lemanske, Robert F; Castells, Mariana; Torres, Maria J; Khan, David; Simon, Hans-Uwe; Bindslev-Jensen, Carsten; Burks, Wesley; Poulsen, Lars K; Sampson, Hugh A; Worm, Margitta; Nadeau, Kari C (2017). Precision Medicine in Allergic Disease - Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Allergy, 72(7), pp. 1006-1021. Wiley-Blackwell 10.1111/all.13132

Vicari, Alain P; Schoepfer, Alain M; Meresse, Bertrand; Goffin, Laurence; Léger, Olivier; Josserand, Soheila; Guégan, Nicolas; Yousefi, Shida; Straumann, Alex; Cerf-Bensussan, Nadine; Simon, Hans-Uwe; Chvatchko, Yolande (2017). Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. mAbs, 9(6), pp. 927-944. Taylor & Francis 10.1080/19420862.2017.1332553

Gevaert, Elien; Zhang, Nan; Krysko, Olga; Lan, Feng; Holtappels, Gabriële; De Ruyck, Natalie; Nauwynck, Hans; Yousefi, Shida; Simon, Hans-Uwe; Bachert, Claus (2017). Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in severe airway inflammation. The Journal of allergy and clinical immunology, 139(6), 1849-1860.e6. Elsevier 10.1016/j.jaci.2017.01.019

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Weber, B; Schlapbach, Christoph; Stuck, M; Simon, Hans-Uwe; Borradori, Luca; Beltraminelli, Helmut; Simon, Dagmar (2017). Distinct interferon-gamma and interleukin-9 expression in cutaneous and oral lichen planus. Journal of the European Academy of Dermatology and Venereology, 31(5), pp. 880-886. Wiley 10.1111/jdv.13989

Mortezavi, Ashkan; Salemi, Souzan; Rupp, Niels J; Rüschoff, Jan Hendrik; Hermanns, Thomas; Poyet, Cedric; Randazzo, Marco; Simon, Hans-Uwe; Moch, Holger; Sulser, Tullio; Wild, Peter; Eberli, Daniel (2017). Negative LC3b immunoreactivity in cancer cells is an independent prognostic predictor of prostate cancer specific death. OncoTarget, 8(19), pp. 31765-31774. Impact Journals LLC 10.18632/oncotarget.15986

Simon, Hans-Uwe; Friis, Robert; Tait, Stephen W G; Ryan, Kevin M (2017). Retrograde signaling from autophagy modulates stress responses. Science signaling, 10(468) American Association for the Advancement of Science 10.1126/scisignal.aag2791

Benarafa, Charaf; Simon, Hans-Uwe (2017). Role of granule proteases in the life and death of neutrophils. Biochemical and biophysical research communications, 482(3), pp. 473-481. Academic Press 10.1016/j.bbrc.2016.11.086

Blanchard, C.; Simon, Dagmar; Schoepfer, A.; Straumann, A.; Simon, Hans-Uwe (2017). Eosinophilic esophagitis: unclear roles of IgE and eosinophils. Journal of internal medicine, 281(5), pp. 448-457. Blackwell Scientific Publications 10.1111/joim.12568

Simon, Hans-Uwe; Friis, Robert; Colombo, María I. (2017). Autophagy. In: eLS Citable reviews in the life sciences (pp. 1-10). Wiley 10.1002/9780470015902.a0021581.pub2

Bousquet, Jean; Grattan, Clive; Bieber, Thomas; Matricardi, Paolo; Simon, Hans-Uwe; Wahn, Ulrich; Muraro, Antonella; Hellings, Peter W; Agache, Ioana (2017). Prediction and prevention of allergy and asthma in EAACI journals (2016). Clinical and translational allergy, 7(46), p. 46. BioMed Central 10.1186/s13601-017-0185-4

Simon, Dagmar; Straumann, Alex; Schoepfer, Alain M; Simon, Hans-Uwe (2017). Current concepts in eosinophilic esophagitis. Allergo journal international, 26(7), pp. 258-266. Springer 10.1007/s40629-017-0037-8

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Bussmann, Christian; Schoepfer, Alain M; Safroneeva, Ekaterina; Haas, Nadine; Godat, Sébastien; Sempoux, Christine; Simon, Hans-Uwe; Straumann, Alex (2016). Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy, 48(12), pp. 1069-1075. Thieme 10.1055/s-0042-117274

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Leu, T; Rauthe, S; Wirth, C; Simon, H-U; Kunzmann, V; Hebestreit, H; Kunzmann, S; Simon, Hans-Uwe (2016). [The Lymphoid Variant of HES (L-HES) as Differential Diagnose of Severe Asthma in Childhood]. Klinische Pädiatrie, 228(06/07), pp. 319-324. Thieme 10.1055/s-0042-112593

Werfel, Thomas; Allam, Jean-Pierre; Biedermann, Tilo; Eyerich, Kilian; Gilles, Stefanie; Guttman-Yassky, Emma; Hoetzenecker, Wolfram; Knol, Edward; Simon, Hans-Uwe; Wollenberg, Andreas; Bieber, Thomas; Lauener, Roger; Schmid-Grendelmeier, Peter; Traidl-Hoffmann, Claudia; Akdis, Cezmi A (2016). Cellular and molecular immunologic mechanisms in patients with atopic dermatitis. Journal of allergy and clinical immunology, 138(2), pp. 336-349. Mosby 10.1016/j.jaci.2016.06.010

Bieber, T; Akdis, C; Lauener, R; Traidl-Hoffmann, C; Schmid-Grendelmeier, P; Schäppi, G; Allam, J-P; Apfelbacher, C; Augustin, M; Beck, L; Biedermann, T; Braun-Fahrländer, C; Chew, F T; Clavel, T; Crameri, R; Darsow, U; Deleuran, M; Dittlein, D; Duchna, H-W; Eichenfeld, L; ... (2016). Global Allergy Forum and 3rd Davos Declaration 2015: Atopic dermatitis/Eczema: challenges and opportunities toward precision medicine. Allergy, 71(5), pp. 588-592. Wiley-Blackwell 10.1111/all.12857

Muraro, Antonella; Lemanske, Robert F; Hellings, Peter W; Akdis, Cezmi A; Bieber, Thomas; Casale, Thomas B; Jutel, Marek; Ong, Peck Y; Poulsen, Lars K; Schmid-Grendelmeier, Peter; Simon, Hans-Uwe; Seys, Sven F; Agache, Ioana (2016). Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Journal of allergy and clinical immunology, 137(5), pp. 1347-1358. Mosby 10.1016/j.jaci.2016.03.010

Straumann, A; Blanchard, C; Radonjic-Hoesli, Susanne; Bussmann, Ch; Hruz, P; Safroneeva, Ekaterina; Simon, Dagmar; Schoepfer, A M; Simon, Hans-Uwe (2016). A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE Families. Allergy, 71(6), pp. 889-900. Wiley-Blackwell 10.1111/all.12879

Dhayade, Sandeep; Kaesler, Susanne; Sinnberg, Tobias; Dobrowinski, Hyazinth; Peters, Stefanie; Naumann, Ulrike; Liu, He; Hunger, Robert E.; Thunemann, Martin; Biedermann, Tilo; Schittek, Birgit; Simon, Hans-Uwe; Feil, Susanne; Feil, Robert (2016). Sildenafil Potentiates a cGMP-Dependent Pathway to Promote Melanoma Growth. Cell reports, 14(11), pp. 2599-2610. Cell Press 10.1016/j.celrep.2016.02.028

Simon, Dagmar; Cianferoni, A; Spergel, J M; Aceves, S; Holbreich, M; Venter, C; Rothenberg, M E; Terreehorst, I; Muraro, A; Lucendo, A J; Schoepfer, A; Straumann, A; Simon, Hans-Uwe (2016). Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity. Allergy, 71(5), pp. 611-620. Wiley-Blackwell 10.1111/all.12846

Metcalfe, Dean D; Pawankar, Ruby; Ackerman, Steven J; Akin, Cem; Clayton, Frederic; Falcone, Franco H; Gleich, Gerald J; Irani, Anne-Marie; Johansson, Mats W; Klion, Amy D; Leiferman, Kristin M; Levi-Schaffer, Francesca; Nilsson, Gunnar; Okayama, Yoshimichi; Prussin, Calman; Schroeder, John T; Schwartz, Lawrence B; Simon, Hans-Uwe; Walls, Andrew F and Triggiani, Massimo (2016). Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases. World Allergy Organization journal, 9, p. 7. Wolters Kluwer Health Lippincott Williams & Wilkins 10.1186/s40413-016-0094-3

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2016). The Role of Autophagy in Cancer and Chemotherapy. In: Hayat, M. (ed.) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Human Diseases: Vol. 8 (pp. 253-265). Academic Press 10.1016/B978-0-12-802937-4.00014-4

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Simon, Hans-Uwe; Simon, Dagmar (2016). Leserbrief zum Beitrag Hypereosinophilie. Swiss medical weekly, 16(4), p. 104. EMH Schweizerischer Ärzteverlag

Simon, Hans-Uwe; Radonjic, Susanne Irene (2016). Eosinophile Granulozyten. In: Biedermann, Tilo; Heppt, Werner; Renz, Harald; Röcken, Martin (eds.) Allergologie (pp. 77-85). Berlin, Heidelberg: Springer 10.1007/978-3-642-37203-2_7

Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356

Simon, Hans-Uwe; Yousefi, Shida; Simon, Dagmar (2016). Basophils can form extracellular DNA traps independent of a functional NADPH oxidase. In: Maurer, Markus; Behrendt, Heidrum (eds.) Allergies: Current challenges and solutions. Proceedings of the 30th Symposium of the Collegium Internationale Allergologicum (CIA) (pp. 67-70). Ospedaletto (Pisa): Pacini editore Medicina

Carr, Tara F; Berdnikovs, Sergejs; Simon, Hans-Uwe; Bochner, Bruce S; Rosenwasser, Lanny J (2016). Eosinophilic bioactivities in severe asthma. World Allergy Organization journal, 9, p. 21. BioMed Central 10.1186/s40413-016-0112-5

Simon, Hans-Uwe; Zangemeister-Wittke, Uwe (2016). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer. Heidelberg: Springer

Yousefi, Shida; Simon, Hans-Uwe (2016). NETosis - Does It Really Represent Nature's "Suicide Bomber"? Frontiers in immunology, 7(328), p. 328. Frontiers Research Foundation 10.3389/fimmu.2016.00328

Stojkov, Darko (2016). Actin polymerization and its glutathionylation are required for NET formation (Submitted). (Dissertation, Institute of Pharmacology, Faculty of Medicine of the University of Bern)

Leu, T; Simon, Hans-Uwe; Hebestreit, H; Kunzmann, S (2015). The Hypereosinophilic Syndromes in Childhood. Klinische Pädiatrie, 227(6-07), pp. 308-313. Thieme 10.1055/s-0035-1555792

He, Zhaoyue; Agostini, Massimiliano; Liu, He; Melino, Gerry; Simon, Hans-Uwe (2015). p73 regulates basal and starvation-induced liver metabolism in vivo. OncoTarget, 6(32), pp. 33178-33190. Impact Journals LLC 10.18632/oncotarget.5090

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Tiligada, Ekaterini; Ishii, Masaru; Riccardi, Carlo; Spedding, Michael; Simon, Hans-Uwe; Teixeira, Mauro Martins; Cuervo, Mario Landys Chovel; Holgate, Stephen T; Levi-Schaffer, Francesca (2015). The expanding role of immunopharmacology: IUPHAR Review 16. British journal of pharmacology, 172(17), pp. 4217-4227. Wiley-Blackwell 10.1111/bph.13219

Boyman, O; Kaegi, C; Akdis, M; Bavbek, S; Bossios, A; Chatzipetrou, A; Eiwegger, T; Firinu, D; Harr, T; Knol, E; Matucci, A; Palomares, O; Schmidt-Weber, C; Simon, Hans-Uwe; Steiner, U C; Vultaggio, A; Akdis, C A; Spertini, F (2015). EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders. Allergy, 70(7), pp. 727-754. Wiley-Blackwell 10.1111/all.12616

Hurrell, Benjamin P; Schuster, Steffen; Grün, Eva; Coutaz, Manuel; Williams, Roderick A; Held, Werner; Malissen, Bernard; Malissen, Marie; Yousefi, Shida; Simon, Hans-Uwe; Müller, Andreas J; Tacchini-Cottier, Fabienne (2015). Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. PLoS pathogens, 11(5), e1004929. Public Library of Science 10.1371/journal.ppat.1004929

Galluzzi, Lorenzo; Pietrocola, Federico; Bravo-San Pedro, José Manuel; Amaravadi, Ravi K; Baehrecke, Eric H; Cecconi, Francesco; Codogno, Patrice; Debnath, Jayanta; Gewirtz, David A; Karantza, Vassiliki; Kimmelman, Alec; Kumar, Sharad; Levine, Beth; Maiuri, Maria Chiara; Martin, Seamus J; Penninger, Josef; Piacentini, Mauro; Rubinsztein, David C; Simon, Hans-Uwe; Simonsen, Anne; ... (2015). Autophagy in malignant transformation and cancer progression. EMBO journal, 34(7), pp. 856-880. Nature Publishing Group 10.15252/embj.201490784

Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570

Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Eveline; Schmid, Ines; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S and Simon, Hans-Uwe (2015). Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular cell, 57(6), pp. 1011-1021. Cell Press 10.1016/j.molcel.2015.01.026

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Targeting disease by immunomodulation. Cell death and differentiation, 22(2), pp. 185-186. Nature Publishing Group 10.1038/cdd.2014.166

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2015). Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. Journal of molecular medicine JMM, 93(2), pp. 159-164. Springer 10.1007/s00109-014-1241-3

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137

Radonjic-Hoesli, Susanne; Valent, Peter; Klion, Amy D; Wechsler, Michael E; Simon, Hans-Uwe (2015). Novel targeted therapies for eosinophil-associated diseases and allergy. Annual review of pharmacology and toxicology, 55(1), pp. 633-656. Annual Reviews Inc. 10.1146/annurev-pharmtox-010814-124407

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

Simon, Hans-Uwe (2015). Regulation of inflammation by cell death in allergic rhinitis. In: Akdis, Cezmi A.; Hellings, Peter W. (eds.) Global Atlas of Allergic Rhinitis and chronic rhinosinusitis (pp. 43-44). European Academy of Allergy and Clinical Immunology

Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/jimmunol.1400028

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2014). Autophagy suppresses melanoma tumorigenesis by inducing senescence. Autophagy, 10(2), pp. 372-373. Landes Bioscience 10.4161/auto.27163

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Simon, Dagmar; Straumann, A.; Simon, Hans-Uwe (2014). Eosinophilic esophagitis and allergy. Digestive diseases, 32(1-2), pp. 30-33. Karger 10.1159/000357006

Geering, Barbara; Stoeckle, Christina; Rozman, Sasa; Oberson, Kevin; Benarafa, Charaf; Simon, Hans-Uwe (2014). DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants. Journal of leukocyte biology, 95(2), pp. 293-303. Society for Leukocyte Biology 10.1189/jlb.0813462

Simon, D.; Aeberhard, C.; Erdemoglu, Y.; Simon, H.-U. (2014). Th17 cells and tissue remodeling in atopic and contact dermatitis. Allergy, 69(1), pp. 125-131. Wiley-Blackwell 10.1111/all.12351

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Simon, Hans-Uwe; Friis, Robert (2014). ATG5: a distinct role in the nucleus. Autophagy, 10(1), pp. 176-177. Landes Bioscience 10.4161/auto.26916

Simon, Hans-Uwe; Straumann, Alex (2014). Immunopathogenesis of eosinophilic esophagitis. Digestive diseases, 32(1-2), pp. 11-14. Karger 10.1159/000357003

Houriet, C.; Simon, H.-U.; Simon, D. (2014). Hypereosinophilic Syndromes. Aktuelle Dermatologie, 40(4), pp. 127-132. Thieme 10.1055/s-0034-1365078

Radonjic-Hösli, Susanne; Simon, Hans-Uwe (2014). Eosinophils. Chemical immunology and allergy, 100, pp. 193-204. Karger 10.1159/000358735

Simon, Hans-Uwe (2014). Eosinophils. In: Global Atlas of Allergy (pp. 58-59). Zurich: EAACI

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Ring, J.; Akdis, C.; Lauener, R.; Schäppi, G.; Traidl-Hoffmann, C.; Akdis, M.; Ammann, W.; Behrendt, H.; Bieber, T.; Biedermann, T.; Bienenstock, J.; Blaser, K.; Braun-Fahrländer, C.; Brocknow, K.; Buters, J.; Crameri, R.; Darsow, U.; Denburg, J.A.; Eyerich, K.; Frei, R.; ... (2014). Global Allergy Forum and Second Davos Declaration 2013 Allergy: Barriers to cure - challenges and actions to be taken. Allergy, 69(8), pp. 978-982. Wiley-Blackwell 10.1111/all.12406

von Gunten, Stephan; Shoenfeld, Yehuda; Blank, Miri; Branch, Donald R.; Vassoöev, Tchavdar; Käsermann, Fabian; Bayy, Jagadeesh; Kaveri, Srini; Simon, Hans-Uwe (2014). IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist. Nature reviews - immunology, 14(5), pp. 349-350. Nature Publishing Group 10.1038/nri3401-c1

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2014). Eosinophil extracellular traps: potential role(s) in eosinophilic diseases. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from Mechanisms to Cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 87-89). Pisa: Pacini Editore S.p.A.

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2014). Eosinophil extracellular trap formation in response to thymic stromal lymphopoietin stimulation. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from mechanisms to cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 83-86). Pisa: Pacini Editore

Simon, Hans-Uwe (2014). IL17, IL22 and tissue remodeling in atopic and contact dermatitis. In: Maurer, Marcus; Behrendt, Heidrun (eds.) Allergies: Current challenges and solutions (pp. 183-186). Paccini editore medicina

Schoepfer, Alain M.; Safroneeva, Ekaterina; Bussmann, Christian; Kuchen, Tanja; Portmann, Susanne; Simon, Hans-Uwe; Straumann, Alex (2013). Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation in a time-dependent manner. Gastroenterology, 145(6), 1230-1236.e2. Elsevier 10.1053/j.gastro.2013.08.015

Simon, Dagmar; Borradori, Luca; Simon, Hans-Uwe (2013). Glucocorticoids in autoimmune bullous diseases: are neutrophils the key cellular target? Journal of Investigative Dermatology, 133(10), pp. 2314-2315. Nature Publishing 10.1038/jid.2013.205

Geering, Barbara; Stoeckle, Christina; Conus, Sébastien; Simon, Hans-Uwe (2013). Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends in immunology, 34(8), pp. 398-409. Elsevier Current Trends 10.1016/j.it.2013.04.002

He, Z.; Simon, H. U. (2013). Autophagy protects from liver injury. Cell death and differentiation, 20(7), pp. 850-851. Nature Publishing Group 10.1038/cdd.2013.43

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2013). Extracellular DNA traps in allergic, infectzious, and autoimmune diseases. Allergy, 68(4), pp. 409-416. Wiley-Blackwell 10.1111/all.12111

Straumann, A.; Hoesli, S.; Bussmann, Ch.; Stuck, M.; Perkins, M.; Collins, L. P.; Payton, M.; Pettipher, R.; Hunter, M.; Steiner, J.; Simon, H.-U. (2013). Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis. Allergy, 68(3), pp. 375-385. Wiley-Blackwell 10.1111/all.12096

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

He, Zhaoyue; Simon, Hans-Uwe (2013). A novel link between p53 and ROS. Cell Cyle, 12(2), pp. 201-202. Landes Bioscience 10.4161/cc.23418

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140

von Gunten, Stephan; Wehrli, Marc; Simon, Hans-Uwe (2013). Cell death in immune thrombocytopenia: novel insights and perspectives. Seminars in hematology, 1(50), pp. 109-115. W.B. Saunders 10.1053/j.seminhematol.2013.03.016

Démoulins, Thomas; Bassi, Isabelle; Thomann-Harwood, Lisa; Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan; Mc Cullogh, Kenneth C (2013). Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells. Nanomedicine-Nanotechnology Biology and Medicine, 9(6), pp. 806-817. Elsevier 10.1016/j.nano.2013.01.002

Stoeckle, C.; Simon, Hans-Uwe (2013). CD8(+) T cells producing IL-3 and IL-5 in non-IgE-mediated eosinophilic diseases. Allergy, 68(12), pp. 1622-1628. Wiley-Blackwell 10.1111/all.12311

Simon, D.; Straumann, A.; Dahinden, C.; Simon, H.-U. (2013). Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis. Allergy, 68(7), pp. 945-948. Wiley-Blackwell 10.1111/all.12157

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

Liu, He; He, Zhaoyue; Simon, Hans-Uwe (2013). Targeting autophagy as a potential therapeutic approach for melanoma therapy. Seminars in Cancer Biology, 5(23), pp. 352-360. Elsevier 10.1016/j.semcancer.2013.06.008

Simon, Dagmar; Simon, Hans-Uwe (2013). Eosinophilic skin diseases. In: Lee, James J.; Rosenberg, Helene F. (eds.) Eosinophils in health and diseases (pp. 442-448). Amsterdam: Elsevier

Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200

Galluzzi, L; Vitale, I; Abrams, J M; Alnemri, E S; Baehrecke, E H; Blagosklonny, M V; Dawson, T M; Dawson, V L; El-Deiry, W S; Fulda, S; Gottlieb, E; Green, D R; Hengartner, M O; Kepp, O; Knight, R A; Kumar, S; Lipton, S A; Lu, X; Madeo, F; Malorni, W; ... (2012). Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell death and differentiation, 19(1), pp. 107-20. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.96

von Gunten, Stephan; Simon, Hans-Uwe (2012). Granulocyte death regulation by naturally occurring autoantibodies. Advances in experimental medicine and biology, 750, pp. 157-172. Wien: Springer

Valent, Peter; Klion, Amy D; Rosenwasser, Lanny J; Arock, Michel; Bochner, Bruce S; Butterfield, Joseph H; Gotlib, Jason; Haferlach, Torsten; Hellmann, Andrzej; Horny, Hans-Peter; Leiferman, Kristin M; Metzgeroth, Georgia; Matsumoto, Kenji; Reiter, Andreas; Roufosse, Florence; Rothenberg, Marc E; Simon, Hans-Uwe; Sotlar, Karl; Vandenberghe, Peter; Weller, Peter F; ... (2012). ICON: Eosinophil Disorders. World Allergy Organization journal, 5(12), pp. 174-181. Hagerstown, Md.: Wolters Kluwer Health Lippincott Williams & Wilkins

Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2012). Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease. Current opinion in immunology, 24(6), pp. 736-9. Kidlington, UK: Elsevier 10.1016/j.coi.2012.08.010

Bochner, Bruce S; Book, Wendy; Busse, William W; Butterfield, Joseph; Furuta, Glenn T; Gleich, Gerald J; Klion, Amy D; Lee, James J; Leiferman, Kristin M; Minnicozzi, Michael; Moqbel, Redwan; Rothenberg, Marc E; Schwartz, Lawrence B; Simon, Hans-Uwe; Wechsler, Michael E; Weller, Peter F (2012). Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). Journal of allergy and clinical immunology, 130(3), pp. 587-96. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.07.024

Wechsler, Michael E; Fulkerson, Patricia C; Bochner, Bruce S; Gauvreau, Gail M; Gleich, Gerald J; Henkel, Tim; Kolbeck, Roland; Mathur, Sameer K; Ortega, Hector; Patel, Jatin; Prussin, Calman; Renzi, Paolo; Rothenberg, Marc E; Roufosse, Florence; Simon, Dagmar; Simon, Hans-Uwe; Wardlaw, Andrew; Weller, Peter F; Klion, Amy D (2012). Novel targeted therapies for eosinophilic disorders. Journal of allergy and clinical immunology, 130(3), pp. 563-71. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.07.027

Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x

Conus, Sébastien; Pop, Cristina; Snipas, Scott J; Salvesen, Guy S; Simon, Hans-Uwe (2012). Cathepsin D primes caspase-8 activation by multiple intra-chain proteolysis. Journal of biological chemistry, 287(25), pp. 21142-51. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M111.306399

Valent, Peter; Klion, Amy D; Horny, Hans-Peter; Roufosse, Florence; Gotlib, Jason; Weller, Peter F; Hellmann, Andrzej; Metzgeroth, Georgia; Leiferman, Kristin M; Arock, Michel; Butterfield, Joseph H; Sperr, Wolfgang R; Sotlar, Karl; Vandenberghe, Peter; Haferlach, Torsten; Simon, Hans-Uwe; Reiter, Andreas; Gleich, Gerald J (2012). Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. Journal of allergy and clinical immunology, 130(3), 607-612.e9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2012.02.019

Simon, Hans-Uwe; Klion, Amy (2012). Therapeutic approaches to patients with hypereosinophilic syndromes. Seminars in hematology, 49(2), pp. 160-70. Philadelphia, Pa.: W.B. Saunders 10.1053/j.seminhematol.2012.01.002

Simon, Dagmar; Simon, Hans-Uwe (2012). New drug targets in atopic dermatitis. Chemical immunology and allergy, 96, pp. 126-131. Basel: Karger

Simon, Hans-Uwe (2012). Autophagy in myocardial differentiation and cardiac development. Circulation research, 110(4), pp. 524-5. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.112.265157

Straumann, A; Aceves, S S; Blanchard, C; Collins, M H; Furuta, G T; Hirano, I; Schoepfer, A M; Simon, D; Simon, H-U (2012). Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy, 67(4), pp. 477-90. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02787.x

Kerstan, A; Simon, H-U; Yousefi, S; Leverkus, M (2012). Extensive accumulation of eosinophil extracellular traps in bullous delayed-pressure urticaria: a pathophysiological link? British journal of dermatology, 166(5), pp. 1151-2. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2012.10848.x

Mihalache, Cristina C; Simon, Hans-Uwe (2012). Autophagy regulation in macrophages and neutrophils. Experimental cell research, 318(11), pp. 1187-92. San Diego, Calif.: Elsevier 10.1016/j.yexcr.2011.12.021

Simon, HU; Yousefi, S (2012). Mitochondrial DNA released by eosinophils contributes to innate immunity. Pisa: Pacini Editore S.p.A.

Simon, HU; Simon, D (2012). Biologics targeting T and B cells improve atopic eczema. Pisa: Pacini Editore S.p.A.

Lammel, Verena; Stoeckle, Christina; Padberg, Barbara; Zweifel, Roland; Kienle, Dirk L; Reinhart, Walter H; Simon, Hans-Uwe (2012). Hypereosinophilia driven by GM-CSF in large-cell carcinoma of the lung. Lung cancer, 76(3), pp. 493-5. Amsterdam: Elsevier 10.1016/j.lungcan.2012.02.014

Simon, HU; Ziegler, S.F. (2012). Allergic responses in the lung and skin: new players in the game. Immunology and allergy clinics of North America, 24(6), pp. 698-699. Philadelphia, Pa.: Elsevier 10.1016/j.coi.2012.10.006

Valent, Peter; Gleich, Gerald J; Reiter, Andreas; Roufosse, Florence; Weller, Peter F; Hellmann, Andrzej; Metzgeroth, Georgia; Leiferman, Kristin M; Arock, Michel; Sotlar, Karl; Butterfield, Joseph H; Cerny-Reiterer, Sabine; Mayerhofer, Matthias; Vandenberghe, Peter; Haferlach, Torsten; Bochner, Bruce S; Gotlib, Jason; Horny, Hans-Peter; Simon, Hans-Uwe and Klion, Amy D (2012). Pathogenesis and classification of eosinophil disorders: a review of recent developments in the field. Expert review of hematology, 5(2), pp. 157-76. London: Expert Reviews 10.1586/EHM.11.81

Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2012). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer (pp. 2437-2440). Heidelberg: Springer-Verlage 10.1007/978-3-642-16483-5

Schaub, A; von Gunten, S; Vogel, M; Wymann, S; Rüegsegger, M; Stadler, B M; Spycher, M; Simon, H-U; Miescher, S (2011). Dimeric IVIG contains natural anti-Siglec-9 autoantibodies and their anti-idiotypes. Allergy, 66(8), pp. 1030-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02579.x

Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206

Casulli, Sarah; Topçu, Selma; Fattoum, Lakhdar; von Gunten, Stephan; Simon, Hans-Uwe; Teillaud, Jean-Luc; Bayry, Jagadeesh; Kaveri, Srini V.; Elbim, Carole (2011). A differential concentration-dependent effect of IVIg on neutrophil functions: relevance for anti-microbial and anti-inflammatory mechanisms. PLoS ONE, 6(10), e26469. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026469

Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan (2011). Targeting siglecs--a novel pharmacological strategy for immuno- and glycotherapy. Biochemical pharmacology, 82(4), pp. 323-32. New York, N.Y.: Elsevier 10.1016/j.bcp.2011.05.018

Hruz, Petr; Straumann, Alex; Bussmann, Christian; Heer, Pius; Simon, Hans-Uwe; Zwahlen, Marcel; Beglinger, Christoph; Schoepfer, Alain M (2011). Escalating incidence of eosinophilic esophagitis: a 20-year prospective, population-based study in Olten County, Switzerland. Journal of allergy and clinical immunology, 128(6), 1349-1350.e5. St. Louis, Mo.: Mosby 10.1016/j.jaci.2011.09.013

Geering Truffer, Barbara; Schmidt-Mende, Jan; Federzoni, Elena; Stoeckle, Christina; Simon, Hans-Uwe (2011). Protein overexpression following lentiviral infection of primary mature neutrophils is due to pseudotransduction. Journal of immunological methods, 373(1-2), pp. 209-18. Amsterdam: Elsevier 10.1016/j.jim.2011.08.024

Roth, N; Städler, S; Lemann, M; Hösli, S; Simon, H-U; Simon, D (2011). Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations. Allergy, 66(11), pp. 1477-86. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02694.x

Geering, Barbara; Simon, Hans-Uwe (2011). A novel signaling pathway in TNF?-induced neutrophil apoptosis. Cell cycle, 10(17), pp. 2821-2. Georgetown, Tex.: Landes Bioscience 10.4161/cc.10.17.16747

Bousquet, Jean; Anto, Josep M; Sterk, Peter J; Adcock, Ian M; Chung, Kian Fan; Roca, Josep; Agusti, Alvar; Brightling, Chris; Cambon-Thomsen, Anne; Cesario, Alfredo; Abdelhak, Sonia; Antonarakis, Stylianos E; Avignon, Antoine; Ballabio, Andrea; Baraldi, Eugenio; Baranov, Alexander; Bieber, Thomas; Bockaert, Joël; Brahmachari, Samir; Brambilla, Christian; ... (2011). Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome medicine, 3(7), p. 43. London: BioMed Central 10.1186/gm259

Geering, B; Simon, H-U (2011). Peculiarities of cell death mechanisms in neutrophils. Cell death and differentiation, 18(9), pp. 1457-69. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.75

Bieber, T; Simon, H-U (2011). Allergen-specific immunotherapy: current concepts and future directions. Allergy, 66(6), pp. 709-12. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02595.x

Mihalache, Cristina C; Yousefi, Shida; Conus, Sébastien; Villiger, Peter M; Schneider, E Marion; Simon, Hans-Uwe (2011). Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events. Journal of immunology, 186(11), pp. 6532-42. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1004055

Stuck, M C; Straumann, A; Simon, H-U (2011). Relative lack of T regulatory cells in adult eosinophilic esophagitis - no normalization after corticosteroid therapy. Allergy, 66(5), pp. 705-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2010.02525.x

Dworski, Ryszard; Simon, Hans-Uwe; Hoskins, Aimee; Yousefi, Shida (2011). Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways. Journal of allergy and clinical immunology, 127(5), pp. 1260-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.12.1103

Straumann, Alex; Conus, Sebastien; Degen, Lukas; Frei, Cornelia; Bussmann, Christian; Beglinger, Christoph; Schoepfer, Alain; Simon, Hans-Uwe (2011). Long-term budesonide maintenance treatment is partially effective for patients with eosinophilic esophagitis. Clinical gastroenterology and hepatology, 9(5), 400-9.e1. Philadelphia, Pa.: Elsevier 10.1016/j.cgh.2011.01.017

Simon, Dagmar; Hoesli, Susanne; Roth, Nina; Staedler, Simon; Yousefi, Shida; Simon, Hans-Uwe (2011). Eosinophil extracellular DNA traps in skin diseases. Journal of allergy and clinical immunology, 127(1), pp. 194-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.11.002

Simon, H.U. (2011). Old and new allergic diseases: From diagnosis to drug therapy. European journal of pharmaceutical sciences, p. 7. Amsterdam: Elsevier

Kroemer, G; Martinon, F; Lippens, S; Green, D.R.; Knight, R; Vandenabeele, G; Piacentini, M; Nagata, S; Borner, C; Simon, H.U.; Kramer, P; Melino, G (2011). Jürg Tschopp - 1951 2011 - an immortal contribution. Cell death and differentiation, 18(7), pp. 1087-1088. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.46

Abbas, M; Lalive, PH; Chofflon, M; Simon, HU; Chizzolini, C; Ribi, C (2011). Hypereosinophilia in patients with mutiple sclerosis treated with natalizumab. Neurology, 77(16), pp. 1561-1564. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1212/WNL.0b013e318233b391

El-Hashim, Ahmed; Yousefi, Shida; Edafiogho, Ivan; Raghupathy, Raj; Yousif, Mariam; Simon, Hans-Uwe (2010). Anti-inflammatory and immunosuppressive effects of the enaminone E121. European journal of pharmacology, 632(1-3), pp. 73-78. Amsterdam: Elsevier 10.1016/j.ejphar.2009.12.004

Schoepfer, Alain M; Gonsalves, Nirmala; Bussmann, Christian; Conus, Sébastien; Simon, Hans-Uwe; Straumann, Alex; Hirano, Ikuo (2010). Esophageal Dilation in Eosinophilic Esophagitis: Effectiveness, Safety, and Impact on the Underlying Inflammation. American journal of gastroenterology, 105(5), pp. 1062-1070. New York, N.Y.: Nature 10.1038/ajg.2009.657

Britschgi, Adrian; Simon, Hans-Uwe; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2010). Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2. British journal of haematology, 149(1), pp. 55-64. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.08040.x

von Gunten, Stephan; Simon, Hans-Uwe (2010). Cell death modulation by intravenous immunoglobulin. Journal of clinical immunology, 30 Suppl 1, S24-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10875-010-9411-8

Schmidt-Mende, Jan; Geering, Barbara; Yousefi, Shida; Simon, Hans-Uwe (2010). Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells. European journal of immunology, 40(2), pp. 525-9. Weinheim: Wiley-VCH 10.1002/eji.200939556

Tschan, M P; Simon, H-U (2010). The role of autophagy in anticancer therapy: promises and uncertainties. Journal of internal medicine, 268(5), pp. 410-8. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2796.2010.02266.x

Straumann, Alex; Conus, Sebastien; Degen, Lukas; Felder, Stephanie; Kummer, Mirjam; Engel, Hansjürg; Bussmann, Christian; Beglinger, Christoph; Schoepfer, Alain; Simon, Hans-Uwe (2010). Budesonide is effective in adolescent and adult patients with active eosinophilic esophagitis. Gastroenterology, 139(5), 1526-37, 1537.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2010.07.048

Simon, Hans-Uwe; Rothenberg, Marc E; Bochner, Bruce S; Weller, Peter F; Wardlaw, Andrew J; Wechsler, Michael E; Rosenwasser, Lanny J; Roufosse, Florence; Gleich, Gerald J; Klion, Amy D (2010). Refining the definition of hypereosinophilic syndrome. Journal of allergy and clinical immunology, 126(1), pp. 45-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.03.042

Conus, Sébastien; Straumann, Alex; Bettler, Eva; Simon, Hans-Uwe (2010). Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis. Journal of allergy and clinical immunology, 126(1), pp. 175-7. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.04.029

Berent-Maoz, Beata; Salemi, Souzan; Mankuta, David; Simon, Hans-Uwe; Levi-Schaffer, Francesca (2010). Human mast cells express intracellular TRAIL. Cellular immunology, 262(2), pp. 80-3. San Diego, Calif.: Elsevier 10.1016/j.cellimm.2010.02.003

Bieber, T; Simon, H-U (2010). Shaping the future of Allergy. Allergy, 65(1), p. 1. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.02272.x

Straumann, A; Conus, S; Grzonka, P; Kita, H; Kephart, G; Bussmann, C; Beglinger, C; Smith, D A; Patel, J; Byrne, M; Simon, H-U (2010). Anti-interleukin-5 antibody treatment (mepolizumab) in active eosinophilic oesophagitis: a randomised, placebo-controlled, double-blind trial. Gut, 59(1), pp. 21-30. London: BMJ Publishing Group 10.1136/gut.2009.178558

Bantel, Heike; Simon, Hans-Uwe (2010). DeltaNp73beta is oncogenic in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria. Cell cycle, 9(14), pp. 2710-1. Georgetown, Tex.: Landes Bioscience 10.4161/cc.9.14.12592

Colombo, María Isabel; Simon, Hans-Uwe (2010). Autophagy: in: Cell Death. In: Melino, Gerry; Vaux, David (eds.) Encyclopedia of Life Sciences (pp. 175-188). Chichester: John Wiley & Sons Ltd. 10.1002/9780470015902.a0021581

Simon, D; Simon, H.-U. (2010). Eosinophils in autoimmune bullous diseases. In: , (ed.) Autoimmune diseases of the skin, 3rd edition. Heidelberg: Springer Verlag

Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2009). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer, 2nd Edition (pp. 2008-2010). Heidelberg: Springer Verlag 10.1007/978-3-540-47648-1_3940

Kassahn, D; Nachbur, U; Conus, S; Micheau, O; Schneider, P; Simon, H-U; Brunner, T (2009). Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell death and differentiation, 16(1), pp. 115-24. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.133

Salemi, S; Yousefi, S; Simon, D; Schmid, I; Moretti, L; Scapozza, L; Simon, H-U (2009). A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. Allergy, 64(6), pp. 913-8. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.01943.x

Ogbogu, Princess U; Bochner, Bruce S; Butterfield, Joseph H; Gleich, Gerald J; Huss-Marp, Johannes; Kahn, Jean Emmanuel; Leiferman, Kristin M; Nutman, Thomas B; Pfab, Florian; Ring, Johannes; Rothenberg, Marc E; Roufosse, Florence; Sajous, Marie-Helene; Sheikh, Javed; Simon, Dagmar; Simon, Hans-Uwe; Stein, Miguel L; Wardlaw, Andrew; Weller, Peter F and Klion, Amy D (2009). Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. Journal of allergy and clinical immunology, 124(6), 1319-25.e3. St. Louis, Mo.: Mosby 10.1016/j.jaci.2009.09.022

Bousquet, P J; Brozek, J; Bachert, C; Bieber, T; Bonini, S; Burney, P; Calderon, M; Canonica, G W; Compalati, E; Daures, J P; Delgado, L; Demoly, P; Dahl, R; Durham, S R; Kowalski, M L; Malling, H J; Merk, H; Papadopoulos, N; Passalacqua, G; Simon, H U; ... (2009). The CONSORT statement checklist in allergen-specific immunotherapy: a GA2LEN paper. Allergy, 64(12), pp. 1737-45. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.02232.x

Yousefi, S; Mihalache, C; Kozlowski, E; Schmid, I; Simon, H U (2009). Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps. Cell death and differentiation, 16(11), pp. 1438-44. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.96

Daryadel, Arezoo; Yousefi, Shida; Troi, David; Schmid, Inès; Schmidt-Mende, Jan; Mordasini, Carlo; Dahinden, Clemens A; Ziemiecki, Andrew; Simon, Hans-Uwe (2009). RhoH/TTF negatively regulates leukotriene production in neutrophils. Journal of immunology, 182(10), pp. 6527-32. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803846

Andina, N; Conus, S; Schneider, E M; Fey, M F; Simon, H U (2009). Induction of Bim limits cytokine-mediated prolonged survival of neutrophils. Cell death and differentiation, 16(9), pp. 1248-55. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.50

Galluzzi, L; Aaronson, S A; Abrams, J; Alnemri, E S; Andrews, D W; Baehrecke, E H; Bazan, N G; Blagosklonny, M V; Blomgren, K; Borner, C; Bredesen, D E; Brenner, C; Castedo, M; Cidlowski, J A; Ciechanover, A; Cohen, G M; De Laurenzi, V; De Maria, R; Deshmukh, M; Dynlacht, B D; ... (2009). Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell death and differentiation, 16(8), pp. 1093-107. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.44

Eisenberg-Lerner, A; Bialik, S; Simon, H-U; Kimchi, A (2009). Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell death and differentiation, 16(7), pp. 966-75. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.33

von Gunten, Stephan; Jakob, Stephan M; Geering, Barbara; Takala, Jukka; Simon, Hans-Uwe (2009). Different patterns of Siglec-9-mediated neutrophil death responses in septic shock. Shock, 32(4), pp. 386-92. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181a1bc98

Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cells of the blood. Biochimica and biophysica acta - molecular and cell biology of lipids, 1793(9), pp. 1461-4. New York, N.Y.: Elsevier 10.1016/j.bbamcr.2008.12.023

Simon, Hans-Uwe; Malhotra, Bimal (2009). The pharmacokinetic profile of fesoterodine: similarities and differences to tolterodine. Swiss medical weekly, 139(9-10), pp. 146-51. Muttenz: EMH Schweizerischer Ärzteverlag

Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cancer and chemotherapy. Results and problems in cell differentiation, 49, pp. 183-190. Berlin: Springer

Simon, Hans-Uwe (2009). Cell death in allergic diseases. Apoptosis, 14(4), pp. 439-46. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10495-008-0299-1

Aits, Sonja; Gustafsson, Lotta; Hallgren, Oskar; Brest, Patrick; Gustafsson, Mattias; Trulsson, Maria; Mossberg, Ann-Kristin; Simon, Hans-Uwe; Mograbi, Baharia; Svanborg, Catharina (2009). HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death. International journal of cancer, 124(5), pp. 1008-19. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.24076

Conus, Sébastien; Straumann, Alex; Simon, Hans-Uwe (2009). Anti-IL-5 (mepolizumab) therapy does not alter IL-5 receptor alpha levels in patients with eosinophilic esophagitis. Journal of allergy and clinical immunology, 123(1), 269; author reply 269-70. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.09.031

Andina, N; Didichenko, S; Schmidt-Mende, J; A.Dahinden, C.; Simon, Hans-Uwe (2009). Pim-1 but not PI3K is essential in the anti-apoptotic signalling casdace initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, pp. 603-611. St. Louis, Mo.: Mosby

Simon, D; Kozlowski, E; U.Simon, H. (2009). NK-T cells in atopic dermatitis. Allergy, 59(6), pp. 561-570. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2004.00476.x

Simon, Hans-Uwe (2009). Regulation of cell survival. In: Adkinson, N. Franklin; Busse, William W; Bochner, Bruce S; Holgate, Stephen T; Simons, Estelle R; Lemanske, Robert F (eds.) Middleton's Allergy: Principles and Practice, 7th Edition (pp. 413-421). Mosby

Colombo, M.I.; Simon, H.U. (2009). Autophagy. In: Encyclopedia of Life Sciences (ELS). Chichester: J. Wiley & Sons

Andina, Nicola; Didichenko, Svetlana; Schmidt-Mende, Jan; Dahinden, Clemens A; Simon, Hans-Uwe (2009). Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils. Journal of allergy and clinical immunology, 123(3), pp. 603-611. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.12.004

Conus, Sébastien; Perozzo, Remo; Reinheckel, Thomas; Peters, Christoph; Scapozza, Leonardo; Yousefi, Shida; Simon, Hans-Uwe (2008). Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation. Journal of experimental medicine, 205(3), pp. 685-698. New York, N.Y.: Rockefeller University Press 10.1084/jem.20072152

Belyanskaya, Larisa L; Ziogas, Algirdas; Hopkins-Donaldson, Sally; Kurtz, Stefanie; Simon, Hans-Uwe; Stahel, Rolf; Zangemeister-Wittke, Uwe (2008). TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8. Lung cancer, 60(3), pp. 355-65. Amsterdam: Elsevier 10.1016/j.lungcan.2007.11.005

Simon, Dagmar; Salemi, Souzan; Yousefi, Shida; Simon, Hans-Uwe (2008). Primary resistance to imatinib in Fip1-like 1-platelet-derived growth factor receptor alpha-positive eosinophilic leukemia. Journal of allergy and clinical immunology, 121(4), pp. 1054-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.027

Federzoni, Elena; Gordon, Grace; Müller, Stefan; Schmid, Inès; Simon, Hans-Uwe; Yousefi, Shida (2008). Expression of CD95 on mature leukocytes of MRL/lpr mice after transplantation of genetically modified bone marrow stem cells. Immunology letters, 117(1), pp. 45-9. Amsterdam: Elsevier 10.1016/j.imlet.2007.11.019

Kostylina, G; Simon, D; Fey, M F; Yousefi, S; Simon, H U (2008). Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A). Cell death and differentiation, 15(1), pp. 134-42. Basingstoke: Nature Publishing Group 10.1038/sj.cdd.4402238

Kuhn, A; Leupin, N; Fey, M.F.; Yousefi, S; Simon, H.U. (2008). Leukaemia cell lines are robust in vitro models - response to MacLeod & Drexler. British journal of haematology(142), pp. 138-141. Oxford: Wiley-Blackwell

Conus, Sébastien; Simon, Hans-Uwe (2008). Cathepsins: key modulators of cell death and inflammatory responses. Biochemical pharmacology, 76(11), pp. 1374-82. New York, N.Y.: Elsevier 10.1016/j.bcp.2008.07.041

Ulrich, Martina; Petre, Alina; Youhnovski, Nikolay; Prömm, Franziska; Schirle, Markus; Schumm, Michael; Pero, Ralph S; Doyle, Alfred; Checkel, James; Kita, Hirohito; Thiyagarajan, Nethaji; Acharya, K Ravi; Schmid-Grendelmeier, Peter; Simon, Hans-Uwe; Schwarz, Heinz; Tsutsui, Masato; Shimokawa, Hiroaki; Bellon, Gabriel; Lee, James J; Przybylski, Michael; ... (2008). Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. Journal of biological chemistry, 283(42), pp. 28629-40. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M801196200

Straumann, Alex; Bussmann, Christian; Conus, Sébastien; Beglinger, Christoph; Simon, Hans-Uwe (2008). Anti-TNF-alpha (infliximab) therapy for severe adult eosinophilic esophagitis. Journal of allergy and clinical immunology, 122(2), pp. 425-7. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.012

Simon, Dagmar; Wittwer, Jennifer; Kostylina, Ganna; Buettiker, Urs; Simon, Hans-Uwe; Yawalkar, Nikhil (2008). Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema. Journal of allergy and clinical immunology, 122(2), pp. 423-4. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.010

von Gunten, Stephan; Simon, Hans-Uwe (2008). Natural anti-Siglec autoantibodies mediate potential immunoregulatory mechanisms: implications for the clinical use of intravenous immunoglobulins (IVIg). Autoimmunity reviews, 7(6), pp. 453-6. Amsterdam: Elsevier 10.1016/j.autrev.2008.03.015

Conus, Sébastien; Simon, Hans-Uwe (2008). General laboratory diagnostics of eosinophilic GI diseases. Best practice & research - clinical gastroenterology, 22(3), pp. 441-53. London: Baillière Tindall 10.1016/j.bpg.2007.09.003

Rothenberg, Marc E; Klion, Amy D; Roufosse, Florence E; Kahn, Jean Emmanuel; Weller, Peter F; Simon, Hans-Uwe; Schwartz, Lawrence B; Rosenwasser, Lanny J; Ring, Johannes; Griffin, Elaine F; Haig, Ann E; Frewer, Paul I H; Parkin, Jacqueline M; Gleich, Gerald J (2008). Treatment of patients with the hypereosinophilic syndrome with mepolizumab. New England journal of medicine NEJM, 358(12), pp. 1215-28. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMoa070812

Simon, Dagmar; Hösli, Susanne; Kostylina, Ganna; Yawalkar, Nikhil; Simon, Hans-Uwe (2008). Anti-CD20 (rituximab) treatment improves atopic eczema. Journal of allergy and clinical immunology, 121(1), pp. 122-8. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.016

Yousefi, Shida; Gold, Jeffrey A; Andina, Nicola; Lee, James J; Kelly, Ann M; Kozlowski, Evelyne; Schmid, Inès; Straumann, Alex; Reichenbach, Janine; Gleich, Gerald J; Simon, Hans-Uwe (2008). Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nature medicine, 14(9), pp. 949-53. New York, N.Y.: Nature Publishing Group 10.1038/nm.1855

Bousquet, J; Fokkens, W; Burney, P; Durham, S R; Bachert, C; Akdis, C A; Canonica, G W; Dahlen, S-E; Zuberbier, T; Bieber, T; Bonini, S; Bousquet, P J; Brozek, J L; Cardell, L-O; Crameri, R; Custovic, A; Demoly, P; van Wijk, R G; Gjomarkaj, M; Holland, C; ... (2008). Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper. Allergy, 63(7), pp. 842-53. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2008.01715.x

Bousquet, J; Bieber, T; Fokkens, W; Kowalski, M; Humbert, M; Niggemann, B; Simon, H-U; Cruz, A A; Haahtela, T (2008). In Allergy, 'A new day has begun'. Allergy, 63(6), pp. 631-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2008.01730.x

Straumann, Alex; Bussmann, Christian; Zuber, Markus; Vannini, Simone; Simon, Hans-Uwe; Schoepfer, Alain (2008). Eosinophilic esophagitis: analysis of food impaction and perforation in 251 adolescent and adult patients. Clinical gastroenterology and hepatology, 6(5), pp. 598-600. Philadelphia, Pa.: Elsevier 10.1016/j.cgh.2008.02.003

Berent-Maoz, B; Salemi, S; Mankuta, D; Simon, H-U; Levi-Schaffer, F (2008). TRAIL mediated signaling in human mast cells: the influence of IgE-dependent activation. Allergy, 63(3), pp. 333-40. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2007.01598.x

Klionsky, Daniel J; Abeliovich, Hagai; Agostinis, Patrizia; Agrawal, Devendra K; Aliev, Gjumrakch; Askew, David S; Baba, Misuzu; Baehrecke, Eric H; Bahr, Ben A; Ballabio, Andrea; Bamber, Bruce A; Bassham, Diane C; Bergamini, Ettore; Bi, Xiaoning; Biard-Piechaczyk, Martine; Blum, Janice S; Bredesen, Dale E; Brodsky, Jeffrey L; Brumell, John H; Brunk, Ulf T; ... (2008). Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy, 4(2), pp. 151-75. Austin, Tex.: Landes Bioscience

Bousquet, J; Bieber, T; Fokkens, W; Kowalski, M L; Humbert, M; Niggemann, B; Simon, H-U; Burney, P; van Cauwenberge, P; Zuberbier, T; Akdis, C A; Demoly, P (2008). Important questions in allergy: novel research areas. Allergy, 63(2), pp. 143-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2007.01615.x

Bousquet, J; Bieber, T; Fokkens, W; Humbert, M; Kowalski, M L; Niggemann, B; Simon, H-U; Schünemann, H (2008). Consensus statements, evidence-based medicine and guidelines in allergic diseases. Allergy, 63(1), pp. 1-4. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2007.01594.x

Simon, HU (2008). Hypereosinophilic syndromes. In: Kay AB, Kaplan AP (ed.) Allergy and Allergic Diseases, 2nd Edition (pp. 1802-1809). Malden, MA: Wiley-Blackwell Publishing

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Rizzi, Mattia; Tschan, Mario P; Britschgi, Christian; Britschgi, Adrian; Hügli, Barbara; Grob, Tobias J; Leupin, Nicolas; Mueller, Beatrice U; Simon, Hans-Uwe; Ziemiecki, Andrew; Torbett, Bruce E; Fey, Martin F; Tobler, Andreas (2007). The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells. Journal of leukocyte biology, 81(6), pp. 1599-608. Bethesda, Md.: Society for Leukocyte Biology 10.1189/jlb.0606400

Yousefi, Shida; Simon, Hans-Uwe (2007). Apoptosis regulation by autophagy gene 5. Critical reviews in oncology, hematology, 63(3), pp. 241-4. Boca Raton, Fla.: Elsevier 10.1016/j.critirevonc.2007.06.005

Simon, Hans-Uwe; Cools, Jan (2007). Novel approaches to therapy of hypereosinophilic syndromes. Immunology and allergy clinics of North America, 27(3), pp. 519-27. Philadelphia, Pa.: Elsevier 10.1016/j.iac.2007.07.003

Hassan, Akmal S; Simon, Dagmar; Simon, Hans-Uwe; Braathen, Lasse R; Yawalkar, Nikhil (2007). Efalizumab-associated papular psoriasis. Archives of dermatology, 143(7), pp. 900-6. Chicago, Ill.: American Medical Association 10.1001/archderm.143.7.900

Simon, D; Braathen, L R; Simon, H-U (2007). Increased lipopolysaccharide-induced tumour necrosis factor-alpha, interferon-gamma and interleukin-10 production in atopic dermatitis. British journal of dermatology, 157(3), pp. 583-6. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2007.08050.x

Simon, Dagmar; Simon, Hans-Uwe (2007). Eosinophilic disorders. Journal of allergy and clinical immunology, 119(6), 1291-300; quiz 1301-2. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.02.010

von Gunten, Stephan; Vogel, Monique; Schaub, Alexander; Stadler, Beda M; Miescher, Sylvia; Crocker, Paul R; Simon, Hans-Uwe (2007). Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. Journal of allergy and clinical immunology, 119(4), pp. 1005-11. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.01.023

Simon, D; Braathen, L R; Simon, H-U (2007). [Anti-interleukin-5 therapy for eosinophilic diseases]. Hautarzt, 58(2), 122, 124-7. Heidelberg: Springer-Verlag 10.1007/s00105-006-1273-x

Simon, Hans-Uwe; Seger, Reinhard (2007). Hyper-IgE syndrome associated with an IL-4-producing gamma/delta(+) T-cell clone. Journal of allergy and clinical immunology, 119(1), pp. 246-8. St. Louis, Mo.: Mosby 10.1016/j.jaci.2006.08.025

von Gunten, Stephan; Simon, Hans-Uwe (2007). Autophagic-like cell death in neutrophils induced by autoantibodies. Autophagy, 3(1), pp. 67-8. Austin, Tex.: Landes Bioscience

Simon, D; Simon, HU (2007). Reply - Eosinophilia in cholesterol atheroembolic disease. Journal of allergy and clinical immunology, 120(6), p. 1471. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.07.013

Yousefi, S; Simon, HU (2007). Taxol Therapy revisited. Blood, 110(2007), p. 3492. Washington, D.C.: American Society of Hematology 10.1182/blood-2007-08-105486

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Daryadel, Arezoo; Grifone, Remo Filippo; Simon, Hans-Uwe; Yousefi, Shida (2006). Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha. Journal of biological chemistry, 281(37), pp. 27653-61. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M604051200

Vassina, Ekatherina M; Yousefi, Shida; Simon, Dagmar; Zwicky, Caroline; Conus, Sébastien; Simon, Hans-Uwe (2006). cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. European journal of immunology, 36(7), pp. 1975-84. Weinheim: Wiley-VCH 10.1002/eji.200635943

Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692

Simon, D; Straumann, A; Wenk, A; Spichtin, H; Simon, H-U; Braathen, L R (2006). Eosinophilic esophagitis in adults--no clinical relevance of wheat and rye sensitizations. Allergy, 61(12), pp. 1480-3. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01224.x

Audigé, Annette; Urosevic, Mirjana; Schlaepfer, Erika; Walker, Russell; Powell, Doug; Hallenberger, Sabine; Joller, Helen; Simon, Hans-Uwe; Dummer, Reinhard; Speck, Roberto F (2006). Anti-HIV state but not apoptosis depends on IFN signature in CD4+ T cells. Journal of immunology, 177(9), pp. 6227-37. Bethesda, Md.: American Association of Immunologists

von Gunten, Stephan; Schaub, Alexander; Vogel, Monique; Stadler, Beda M; Miescher, Sylvia; Simon, Hans-Uwe (2006). Immunologic and functional evidence for anti-Siglec-9 autoantibodies in intravenous immunoglobulin preparations. Blood, 108(13), pp. 4255-9. Washington, D.C.: American Society of Hematology 10.1182/blood-2006-05-021568

Klion, Amy D; Bochner, Bruce S; Gleich, Gerald J; Nutman, Thomas B; Rothenberg, Marc E; Simon, Hans-Uwe; Wechsler, Michael E; Weller, Peter F; The Hypereosinophilic Syndromes Working Group, (2006). Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. Journal of allergy and clinical immunology, 117(6), pp. 1292-302. St. Louis, Mo.: Mosby 10.1016/j.jaci.2006.02.042

Simon, Dagmar; Lindberg, Raija L P; Kozlowski, Evelyne; Braathen, Lasse R; Simon, Hans-Uwe (2006). Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions. Experimental dermatology, 15(6), pp. 441-6. Oxford: Blackwell 10.1111/j.0906-6705.2006.00428.x

von Gunten, Stephan; Simon, Hans-Uwe (2006). Sialic acid binding immunoglobulin-like lectins may regulate innate immune responses by modulating the life span of granulocytes. FASEB journal, 20(6), pp. 601-5. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.05-5401hyp

Simon, Hans-Uwe (2006). Cytokine and anti-cytokine therapy for asthma. Current allergy and asthma reports, 6(2), pp. 117-21. Philadelphia, Pa.: Springer 10.1007/s11882-006-0049-9

Simon, Hans-Uwe (2006). Molecules involved in the regulation of eosinophil apoptosis. Chemical immunology and allergy, 91, pp. 49-58. Basel: Karger

Merendino, Anna M; Bucchieri, Fabio; Gagliardo, Rosalia; Daryadel, Arezoo; Pompeo, Flora; Chiappara, Giuseppina; Santagata, Roberta; Bellia, Vincenzo; David, Sabrina; Farina, Felicia; Davies, Donna E; Simon, Hans-Uwe; Vignola, Antonio M (2006). CD40 ligation protects bronchial epithelium against oxidant-induced caspase-independent cell death. American journal of respiratory cell and molecular biology, 35(2), pp. 155-64. New York, N.Y.: American Lung Association 10.1165/rcmb.2005-0433OC

Berent-Maoz, Beata; Piliponsky, Adrian M; Daigle, Isabelle; Simon, Hans-Uwe; Levi-Schaffer, Francesca (2006). Human mast cells undergo TRAIL-induced apoptosis. Journal of immunology, 176(4), pp. 2272-8. Bethesda, Md.: American Association of Immunologists

Bousquet, J; Bieber, T; Fokkens, W; Humbert, M; Kowalski, M; Niggemann, B; Simon, H-U (2006). Themes in allergy. Allergy, 61(1), pp. 1-2. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2006.01020.x

Simon, D; Braathen, LR; Simon, HU (2006). Hypereosinophilie Syndrome. Allergologie(29), pp. 354-361. München-Deisenhofen: Dustri-Verlag

Baumann, Ralf; Yousefi, Shida; Simon, Dagmar; Russmann, Stefan; Mueller, Christoph; Simon, Hans-Uwe (2004). Functional expression of CD134 by neutrophils. European journal of immunology, 34(8), pp. 2268-2275. Wiley-VCH 10.1002/eji.200424863

Altznauer, Frank; Martinelli, Sibylla; Yousefi, Shida; Thürig, Christine; Schmid, Inès; Conway, Edward M; Schöni, Martin H; Vogt, Peter; Mueller, Christoph; Fey, Martin F; Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2004). Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils. The Journal of experimental medicine, 199(10), pp. 1343-1354. Rockefeller Univ. Press 10.1084/jem.20032033

Simon, Manuel

Stefan, Nikolas; Zimmermann, Martina; Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2014). Novel Prodrug-Like Fusion Toxin with Protease-Sensitive Bioorthogonal PEGylation for Tumor Targeting. Bioconjugate chemistry, 25(12), pp. 2144-2156. American Chemical Society 10.1021/bc500468s

Simon, Manuel; Stefan, Nikolas; Borsig, Lubor; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2014). Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation. Molecular cancer therapeutics, 2(13), pp. 375-385. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0523

Simon, Manuel; Frey, Raphael; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2013). Orthogonal assembly of a designed ankyrin repeat protein-cytotoxin conjugate with a clickable serum albumin module for half-life extension. Bioconjugate chemistry, 24(11), pp. 1955-1986. American Chemical Society 10.1021/bc4004102

Simon, Manuel; Stefan, Nikolas; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2013). Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy. Expert opinion on drug delivery, 10(4), pp. 451-468. Taylor & Francis 10.1517/17425247.2013.759938

Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2012). Facile double-functionalization of designed ankyrin repeat proteins using click and thiol chemistries. Bioconjugate chemistry, 23(2), pp. 279-86. Washington, D.C.: American Chemical Society 10.1021/bc200591x

Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2009). Effects of potentised substances on growth rate of the water plant Lemna gibba L. Complementary therapies in medicine, 17(2), pp. 63-70. Exeter: Elsevier 10.1016/j.ctim.2008.10.004

Scherr, C; Simon, M; Spranger, J; Baumgartner, S (2008). Test System Stability and Natural Variability of a Lemna Gibba L. Bioassay. PLoS ONE, 3(9), e3133. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0003133

Singh, Pushpita

Hugonnet, Marjolaine; Singh, Pushpita; Haas, Quentin; von Gunten, Stephan (2021). The Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology. Frontiers in immunology, 12, p. 799861. Frontiers Research Foundation 10.3389/fimmu.2021.799861

Siontis, Georgios

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2023). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. (In Press). Thrombosis and haemostasis Thieme 10.1055/a-2156-7872

Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

Bär, Sarah; Kavaliauskaite, Raminta; Otsuka, Tatsuhiko; Ueki, Yasushi; Häner, Jonas D; Siontis, George C M; Stortecky, Stefan; Shibutani, Hiroki; Temperli, Fabrice; Kaiser, Christoph; Iglesias, Juan; Jan van Geuns, Robert; Daemen, Joost; Spirk, David; Engstrøm, Thomas; Lang, Irene; Windecker, Stephan; Koskinas, Konstantinos C; Losdat, Sylvain and Räber, Lorenz (2023). Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention, 19(4), e286-e296. Europa Digital & Publishing 10.4244/EIJ-D-23-00201

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Sokollik, Christiane; Simon, Hans-Uwe (2019). [Eosinophilic granulocytes-Physiology and pathophysiology]. Zeitschrift für Rheumatologie, 78(4), pp. 306-312. Springer-Medizin-Verlag 10.1007/s00393-018-0574-7

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

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Soria Maldonado, Rodrigo

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Sousa Augusto, Gilles Anderson

Plattner, Kevin; Sousa Augusto, Gilles; Muerner, Lukas; von Gunten, Stephan; Jörg, Lukas; Engeroff, Paul; Bachmann, Martin F; Vogel, Monique (2023). IgE glycosylation is essential for the function of omalizumab. Allergy, 78(9), pp. 2546-2549. Wiley 10.1111/all.15748

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Spinetti, Thibaud; Meisel, Christian; von Gunten, Stephan; Schefold, Joerg C. (2020). Immune biomarker-based enrichment in sepsis trials. Critical care, 24(1), p. 58. BioMed Central 10.1186/s13054-020-2774-1

Spirk, David

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

Wortmann, Julian Kleine; Barco, Stefano; Fumagalli, Riccardo M; Voci, Davide; Hügel, Ulrike; Cola, Rahel; Spirk, David; Kucher, Nils; Sebastian, Tim (2023). Coagulation-monitored, dose-adjusted catheter-directed thrombolysis or pharmaco-mechanical thrombus removal in deep vein thrombosis. Vasa - European journal of vascular medicine, 52(6), pp. 416-422. Huber 10.1024/0301-1526/a001097

Barco, Stefano; Virdone, Saverio; Götschi, Andrea; Ageno, Walter; Arcelus, Juan I; Bingisser, Roland; Colucci, Giuseppe; Cools, Frank; Duerschmied, Daniel; Gibbs, Harry; Fumagalli, Riccardo M; Gerber, Bernhard; Haas, Sylvia; Himmelreich, Jelle C L; Hobbs, Richard; Hobohm, Lukas; Jacobson, Barry; Kayani, Gloria; Lopes, Renato D; MacCallum, Peter; ... (2023). Enoxaparin for symptomatic COVID-19 managed in the ambulatory setting: An individual patient level analysis of the OVID and ETHIC trials. Thrombosis research, 230, pp. 27-32. Elsevier 10.1016/j.thromres.2023.08.009

Ueki, Yasushi; Häner, Jonas; Losdat, Sylvain; Gargiulo, Giuseppe; Shibutani, Hiroki; Bär, Sarah; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Mitter, Vera; Temperli, Fabrice; Spirk, David; Stortecky, Stefan; Siontis, George; Valgimigli, Marco; Windecker, Stephan; Gutmann, Clemens; Koskinas, Konstantinos C; Mayr, Manuel; Raber, Lorenz (2023). Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. (In Press). Thrombosis and haemostasis Thieme 10.1055/a-2156-7872

Biccirè, Flavio G; Häner, Jonas; Losdat, Sylvain; Ueki, Yasushi; Shibutani, Hiroki; Otsuka, Tatsuhiko; Kakizaki, Ryota; Hofbauer, Thomas M; van Geuns, Robert-Jan; Stortecky, Stefan; Siontis, Georgios Cm; Bär, Sarah; Lønborg, Jacob; Heg, Dik; Kaiser, Christoph; Spirk, David; Daemen, Joost; Iglesias, Juan; Windecker, Stephan; Engstrøm, Thomas; ... (2023). Concomitant Coronary Atheroma Regression and Stabilization in Response to Lipid-Lowering Therapy. Journal of the American College of Cardiology, 82(18), pp. 1737-1747. Elsevier 10.1016/j.jacc.2023.08.019

Bär, Sarah; Kavaliauskaite, Raminta; Otsuka, Tatsuhiko; Ueki, Yasushi; Häner, Jonas D; Siontis, George C M; Stortecky, Stefan; Shibutani, Hiroki; Temperli, Fabrice; Kaiser, Christoph; Iglesias, Juan; Jan van Geuns, Robert; Daemen, Joost; Spirk, David; Engstrøm, Thomas; Lang, Irene; Windecker, Stephan; Koskinas, Konstantinos C; Losdat, Sylvain and Räber, Lorenz (2023). Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention, 19(4), e286-e296. Europa Digital & Publishing 10.4244/EIJ-D-23-00201

Voci, Davide; Fedeli, Ugo; Valerio, Luca; Schievano, Elena; Righini, Marc; Kucher, Nils; Spirk, David; Barco, Stefano (2023). Mortality rate related to peripheral arterial disease: A retrospective analysis of epidemiological data (years 2008-2019). Nutrition, metabolism, and cardiovascular diseases : NMCD, 33(3), pp. 516-522. Elsevier 10.1016/j.numecd.2022.11.020

Voci, Davide; Götschi, Andrea; Held, Ulrike; Bingisser, Roland; Colucci, Giuseppe; Duerschmied, Daniel; Fumagalli, Riccardo M; Gerber, Bernhard; Hasse, Barbara; Keller, Dagmar I; Konstantinides, Stavros V; Mach, François; Rampini, Silvana K; Righini, Marc; Robert-Ebadi, Helia; Rosemann, Thomas; Roth-Zetzsche, Stéphanie; Sebastian, Tim; Simon, Noemi R; Spirk, David; ... (2023). Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial. Thrombosis research, 221, pp. 157-163. Elsevier 10.1016/j.thromres.2022.10.021

Dopheide, Jörn F; Gillmann, Patrick; Spirk, David; Khorrami Borozadi, Meisam; Adam, Luise; Drexel, Heinz (2022). False versus True Statin Intolerance in Patients with Peripheral Artery Disease. Journal of clinical medicine, 11(22), p. 6619. MDPI 10.3390/jcm11226619

Wolf, Simon; Spirk, David; Forgo, Gabor; Sebastian, Tim; Voci, Davide; Kucher, Nils; Barco, Stefano (2022). Prevalent use of high-intensity statin therapy and LDL-C target attainment among PAD patients undergoing angioplasty. Vasa : European journal of vascular medicine, 51(6), pp. 357-364. Hogrefe 10.1024/0301-1526/a001025

Müller, Stephanie; Tittl, Luise; Speed, Victoria; Roberts, Lara; Patel, Jignesh; Patel, Raj; Arya, Roopen; Kucher, Nils; Spirk, David; Sahin, Kurtulus; Beyer-Westendorf, Jan (2022). Pooled Analysis of Rivaroxaban therapy for acute venous thromboembolism in FIRST registry, SWIVTER and DRESDEN NOAC registry. Research and practice in thrombosis and haemostasis, 6(7), e12829. Wiley 10.1002/rth2.12829

Frey, Vincent; Sebastian, Tim; Barco, Stefano; Spirk, David; Hayoz, Daniel; Périard, Daniel; Kucher, Nils; Betticher, Daniel; Engelberger, Rolf P (2022). Impact of concomitant popliteal vein thrombosis in patients with acute iliofemoral deep vein thrombosis treated with endovascular early thrombus removal. Vasa : European journal of vascular medicine, 51(5), pp. 282-290. Hogrefe 10.1024/0301-1526/a001017

Barco, Stefano; Voci, Davide; Held, Ulrike; Sebastian, Tim; Bingisser, Roland; Colucci, Giuseppe; Duerschmied, Daniel; Frenk, André; Gerber, Bernhard; Götschi, Andrea; Konstantinides, Stavros V; Mach, François; Robert-Ebadi, Helia; Rosemann, Thomas; Simon, Noemi R; Spechbach, Hervé; Spirk, David; Stortecky, Stefan; Vaisnora, Lukas; Righini, Marc; ... (2022). Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial. The Lancet. Haematology, 9(8), e585-e593. Elsevier 10.1016/S2352-3026(22)00175-2

Sudano, Isabella; Mach, Francois; Moccetti, Tiziano; Burkard, Thilo; Fahe, Christian; Delabays, Alain; Rickli, Hans; Keller, Pierre-Frédéric; Dopheide, Jörn; Bodenmann, Sereina; Fiolka, Tom; Ehret, Georg; Spirk, David (2022). Optimized Treatment of Refractory Hypercholesterolemia in Patients With Atherosclerotic Cardiovascular Disease or Heterozygous Familial Hypercholesterolemia With Alirocumab (OPTIMIZE). Frontiers in cardiovascular medicine, 9, p. 953040. Frontiers 10.3389/fcvm.2022.953040

Räber, Lorenz; Ueki, Yasushi; Otsuka, Tatsuhiko; Losdat, Sylvain; Häner, Jonas D; Lonborg, Jacob; Fahrni, Gregor; Iglesias, Juan F; van Geuns, Robert-Jan; Ondracek, Anna S; Radu Juul Jensen, Maria D; Zanchin, Christian; Stortecky, Stefan; Spirk, David; Siontis, George C; Saleh, Lanja; Matter, Christian M; Daemen, Joost; Mach, François; Heg, Dik; ... (2022). Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial. JAMA - the journal of the American Medical Association, 327(18), pp. 1771-1781. American Medical Association 10.1001/jama.2022.5218

Neuenschwander, Julia; Sebastian, Tim; Barco, Stefano; Spirk, David; Kucher, Nils (2022). A novel management strategy for treatment of pelvic venous disorders utilizing a clinical screening score and non-invasive imaging. Vasa : European journal of vascular medicine, 51(3), pp. 182-189. Hogrefe 10.1024/0301-1526/a001001

Spirk, David; Sebastian, Tim; Beer, Jürg Hans; Mazzolai, Lucia; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf Peter; Korte, Wolfgang; Kucher, Nils; Barco, Stefano (2022). Role of age, sex, and specific provoking factors on the distal versus proximal presentation of first symptomatic deep vein thrombosis: analysis of the SWIss Venous ThromboEmbolism Registry (SWIVTER). Internal and emergency medicine, 17(3), pp. 799-803. Springer 10.1007/s11739-021-02878-7

Wenger, Nicolas; Sebastian, Tim; Engelberger, Rolf Peter; Kucher, Nils; Spirk, David (2021). Pulmonary embolism and deep vein thrombosis: Similar but different. Thrombosis research, 206, pp. 88-98. Elsevier 10.1016/j.thromres.2021.08.015

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Barco, Stefano; Valerio, Luca; Gallo, Andrea; Turatti, Giacomo; Mahmoudpour, Seyed Hamidreza; Ageno, Walter; Castellucci, Lana A; Cesarman-Maus, Gabriela; Ddungu, Henry; De Paula, Erich Vinicius; Dumantepe, Mert; Goldhaber, Samuel Z; Guillermo Esposito, Maria Cecilia; Klok, Frederikus A; Kucher, Nils; McLintock, Claire; Ní Áinle, Fionnuala; Simioni, Paolo; Spirk, David; Spyropoulos, Alex C; ... (2021). Global reporting of pulmonary embolism-related deaths in the World Health Organization mortality database: Vital registration data from 123 countries. Research and practice in thrombosis and haemostasis, 5(5), e12520. Wiley 10.1002/rth2.12520

Zanchin, Christian; Ueki, Yasushi; Losdat, Sylvain; Fahrni, Gregor; Daemen, Joost; Ondracek, Anna S; Häner, Jonas D.; Stortecky, Stefan; Otsuka, Tatsuhiko; Siontis, George C.M.; Rigamonti, Fabio; Radu, Maria; Spirk, David; Kaiser, Christoph; Engstrom, Thomas; Lang, Irene; Koskinas, Konstantinos C.; Räber, Lorenz (2021). In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study. European heart journal - cardiovascular imaging, 22(7), pp. 824-834. Oxford University Press 10.1093/ehjci/jez318

Spirk, David; Sebastian, Tim; Barco, Stefano; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Blondon, Marc; Kucher, Nils (2021). Clinical Outcomes of Incidental Venous Thromboembolism in Cancer and Noncancer Patients: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 121(5), pp. 641-649. Thieme 10.1055/s-0040-1720977

Nagler, Michael; Asmis, Lars M.; Gerber, Bernhard; Ruosch, Sabine; Spirk, David; Surbek, Daniel; Studt, Jan-Dirk; Tsakiris, Dimitrios A.; Wuillemin, Walter A. (2021). Venöse Thromboembolie in Gynäkologie und Geburtshilfe. Swiss Medical Forum, 21(29-30), pp. 503-508. EMH Swiss Medical Publishers 10.4414/smf.2021.08773

Sebastian, Tim; Gnanapiragasam, Suvetha; Spirk, David; Engelberger, Rolf Peter; Moeri, Laura; Lodigiani, Corrado; Kreuzpointner, Robert; Barco, Stefano; Kucher, Nils (2020). Self-Expandable Nitinol Stents for the Treatment of Nonmalignant Deep Venous Obstruction. Circulation. Cardiovascular interventions, 13(12), pp. 366-374. American Heart Association 10.1161/CIRCINTERVENTIONS.120.009673

Sebastian, Tim; Barco, Stefano; Engelberger, Rolf P; Spirk, David; Schindewolf, Marc; Baumann, Frederic; Baumgartner, Iris; Kucher, Nils (2020). Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. European journal of vascular and endovascular surgery EJVES, 60(3), pp. 443-450. Elsevier 10.1016/j.ejvs.2020.05.011

Spirk, David; Noll, Sarah; Burnier, Michel; Rimoldi, Stefano; Noll, Georg; Sudano, Isabella (2020). First Line CombinAtion Therapy in the Treatment of Stage II and III Hypertension (FLASH). Frontiers in cardiovascular medicine, 7(46), p. 46. Frontiers 10.3389/fcvm.2020.00046

Sebastian, Tim; Spirk, David; Engelberger, Rolf P; Dopheide, Jörn F.; Baumann, Frederic A; Barco, Stefano; Spescha, Rebecca; Leeger, Claudia; Kucher, Nils (2019). Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome. Thrombosis and haemostasis, 119(12), pp. 2064-2073. Thieme 10.1055/s-0039-1697955

Spirk, David; Sebastian, Tim; Banyai, Martin; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Aujesky, Drahomir; Hayoz, Daniel; Engelberger, Rolf P; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Mollet, Annette; Szucs, Thomas D; Kucher, Nils (2019). Venous Thromboembolism and Renal Impairment: Insights from the SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 45(8), pp. 851-858. Thieme Medical Publishers 10.1055/s-0039-1698770

Schnetzler, Gabriel; Bremgartner, Markus F; Grossmann Straessle, Regina; Spirk, David; Tay, Fabian; Troxler Saxer, Rahel; Traber, Martin (2019). Evolution to a Competency-Based Training Curriculum for Pharmaceutical Medicine Physicians in Switzerland. Frontiers in Pharmacology, 10(164), p. 164. Frontiers 10.3389/fphar.2019.00164

Sebastian, Tim; Hakki, Lawrence O; Spirk, David; Baumann, Frederic A; Périard, Daniel; Banyai, Martin; Spescha, Rebecca S; Kucher, Nils; Engelberger, Rolf P (2018). Rivaroxaban or vitamin-K antagonists following early endovascular thrombus removal and stent placement for acute iliofemoral deep vein thrombosis. Thrombosis research, 172, pp. 86-93. Elsevier 10.1016/j.thromres.2018.10.027

Miserez, A R; Martin, F J; Spirk, David (2018). DIAgnosis and Management Of familial hypercholesterolemia in a Nationwide Design (DIAMOND-FH): Prevalence in Switzerland, clinical characteristics and the diagnostic value of clinical scores. Atherosclerosis, 277, pp. 282-288. Elsevier 10.1016/j.atherosclerosis.2018.08.009

Sebastian, Tim; Dopheide, Jörn F.; Engelberger, Rolf P.; Spirk, David; Kucher, Nils (2018). Outcomes of endovascular reconstruction of the inferior vena cava with self-expanding nitinol stents. Journal of vascular surgery. Venous and lymphatic disorders, 6(3), pp. 312-320. Elsevier 10.1016/j.jvsv.2017.11.012

Blondon, Marc; Spirk, David; Kucher, Nils; Aujesky, Drahomir; Hayoz, Daniel; Beer, Jürg H; Husmann, Marc; Frauchiger, Beat; Korte, Wolfgang; Wuillemin, Walter Alfred; Bounameaux, Henri; Righini, Marc; Nendaz, Mathieu (2018). Comparative Performance of Clinical Risk Assessment Models for Hospital-Acquired Venous Thromboembolism in Medical Patients. Thrombosis and haemostasis, 118(1), pp. 82-89. Schattauer 10.1160/TH17-06-0403

Spirk, David; Noll, Sarah; Burnier, Michel; Rimoldi, Stefano; Noll, Georg; Sudano, Isabella (2018). Effect of Home Blood Pressure Monitoring on Patient's Awareness and Goal Attainment Under Antihypertensive Therapy: The Factors Influencing Results in Anti-HypertenSive Treatment (FIRST) Study. Kidney & blood pressure research, 43(3), pp. 979-986. Karger 10.1159/000490687

Alatri, Adriano; Mazzolai, Lucia; Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Engelberger, Rolf P.; Baumgartner, Iris; Spirk, David (2017). The Modified Ottawa Score and Clinical Events in Hospitalized Patients with Cancer-Associated Thrombosis from the Swiss VTE Registry. Seminars in thrombosis and hemostasis, 43(8), pp. 871-876. Thieme Medical Publishers 10.1055/s-0037-1604086

Spirk, David; Stuck, Anna K.; Hager, A; Engelberger, Rolf P.; Aujesky, Drahomir; Kucher, Nils (2017). Electronic alert system for improving appropriate thromboprophylaxis in hospitalized medical patients: a randomized controlled trial. Journal of thrombosis and haemostasis, 15(11), pp. 2138-2146. Wiley-Blackwell 10.1111/jth.13812

Engelberger, Rolf P.; Stuck, Anna; Spirk, David; Willenberg, Torsten; Haine, Axel; Périard, Daniel; Baumgartner, Iris; Kucher, Nils (2017). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute ilio-femoral deep vein thrombosis: one-year follow-up data of a randomized-controlled trial. Journal of thrombosis and haemostasis, 15(7), pp. 1351-1360. Wiley-Blackwell 10.1111/jth.13709

Petrova-Slater, Iveta; Denegri, Andrea; Pasotti, Elena; Rossi, Maria Grazia; Spirk, David; Riesen, Walter F; Moccetti, Tiziano; Moccetti, Marco (2017). [Inhibitors of PCSK9]. Revue médicale suisse, 13(558), pp. 821-825. Médecine & Hygiène

Stuck, Anna K.; Spirk, David; Schaudt, Jil; Kucher, Nils (2017). Risk assessment models for venous thromboembolism in acutely ill medical patients. A systematic review. Thrombosis and haemostasis, 117(4), pp. 801-808. Schattauer 10.1160/TH16-08-0631

Spirk, David; Aujesky, Drahomir; Stuck, Anna K; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Kucher, Nils (2016). Clinical Outcomes of Venous Thromboembolism in Patients with and without Cancer: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Seminars in thrombosis and hemostasis, 42(6), pp. 642-649. Thieme Medical Publishers 10.1055/s-0036-1584131

Kucher, Nils; Aujesky, Drahomir; Beer, Jürg H; Mazzolai, Lucia; Baldi, Thomas; Banyai, Martin; Hayoz, Daniel; Kaeslin, Thomas; Korte, Wolfgang; Escher, Robert; Husmann, Marc; Frauchiger, Beat; Baumgartner, Iris; Spirk, David (2016). Rivaroxaban for the treatment of venous thromboembolism. The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thrombosis and haemostasis, 116(3), pp. 472-479. Schattauer 10.1160/TH16-03-0209

Silbernagel, Günther; Spirk, David; Hager, Adrian; Baumgartner, Iris; Kucher, Nils (2016). Electronic Alert System for Improving Stroke Prevention Among Hospitalized Oral-Anticoagulation-Naïve Patients With Atrial Fibrillation: A Randomized Trial. Journal of the American Heart Association, 5(7), pp. 1-7. American Heart Association 10.1161/JAHA.116.003776

Wuillemin, Walter; Spirk, David; Beer, Jürg; Baumgartner, Iris (2016). Schweizer Expertenkommentare zum Update der ACCP-Guidelines. Swiss Medical Forum, 16(49-50), pp. 1059-1060. EMH Swiss Medical Publishers

Spirk, David; Nendaz, M; Aujesky, Drahomir; Hayoz, D; Beer, J H; Husmann, M; Frauchiger, B; Korte, W; Wuillemin, Walter Alfred; Righini, M; Bounameaux, H; Kucher, Nils (2015). Predictors of thromboprophylaxis in hospitalised medical patients. Explicit ASsessment of Thromboembolic RIsk and Prophylaxis for Medical PATients in SwitzErland (ESTIMATE). Thrombosis and haemostasis, 113(5), pp. 1127-1134. Schattauer 10.1160/TH14-06-0525

Engelberger, Rolf Peter; Spirk, David; Willenberg, Torsten Andreas; Alatri, Adriano; Do, Dai-Do; Baumgartner, Iris; Kucher, Nils (2015). Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. Circulation: Cardiovascular interventions, 8(1) Lippincott Williams & Wilkins 10.1161/CIRCINTERVENTIONS.114.002027

Riebenfeld, Daniela; Spirk, David; Mathis, Alexandra; Villiger, Lukas; Gerber, Philipp A; Gasser, Urs Erwin; Lehmann, Roger (2015). Treatment intensification with insulin glargine in patients with inadequately controlled type 2 diabetes improves glycaemic control with a high treatment satisfaction and no weight gain. Swiss medical weekly, 145, w14114. EMH Schweizerischer Ärzteverlag 10.4414/smw.2015.14114

Späth, Peter Julius

Maurer, M; Magerl, M; Betschel, S; Aberer, W; Ansotegui, I J; Aygören-Pürsün, E; Banerji, A; Bara, N A; Boccon-Gibod, I; Bork, K; Bouillet, L; Boysen, H B; Brodszki, N; Busse, P J; Bygum, A; Caballero, T; Cancian, M; Castaldo, A; Cohn, D M; Csuka, D; ... (2023). [Not Available]. Arerugi = [Allergy], 72(3), pp. 237-272. 10.15036/arerugi.72.237

Maurer, M; Magerl, M; Betschel, S; Aberer, W; Ansotegui, I J; Aygören-Pürsün, E; Banerji, A; Bara, N A; Boccon-Gibod, I; Bork, K; Bouillet, L; Boysen, H B; Brodszki, N; Busse, P J; Bygum, A; Caballero, T; Cancian, M; Castaldo, A; Cohn, D M; Csuka, D; ... (2023). [Not Available]. Arerugi = [Allergy], 72(8), p. 1084. Japanese Society of Allergology 10.15036/arerugi.72.1084

Maurer, Marcus; Magerl, Markus; Betschel, Stephen; Aberer, Werner; Ansotegui, Ignacio J; Aygören-Pürsün, Emel; Banerji, Aleena; Bara, Noémi-Anna; Boccon-Gibod, Isabelle; Bork, Konrad; Bouillet, Laurence; Boysen, Henrik Balle; Brodszki, Nicholas; Busse, Paula J; Bygum, Anette; Caballero, Teresa; Cancian, Mauro; Castaldo, Anthony J; Cohn, Danny M; Csuka, Dorottya; ... (2022). The international WAO/EAACI guideline for the management of hereditary angioedema - The 2021 revision and update. World Allergy Organization journal, 15(3), p. 100627. Wolters Kluwer Health Lippincott Williams & Wilkins 10.1016/j.waojou.2022.100627

Dalakas, Marinos C.; Späth, Peter J. (2021). The importance of FcRn in neuro-immunotherapies: From IgG catabolism, FCGRT gene polymorphisms, IVIg dosing and efficiency to specific FcRn inhibitors. Therapeutic advances in neurological disorders, 14, p. 1756286421997381. Sage 10.1177/1756286421997381

Wahn, V; Aberer, W; Aygören-Pürsün, E; Bork, K; Eberl, W; Faßhauer, M; Krüger, R; Magerl, M; Martinez-Saguer, I; Späth, P.; Staubach-Renz, P; Weber-Chrysochoou, C (2020). Hereditary angioedema in children and adolescents - A consensus update on therapeutic strategies for German-speaking countries. Pediatric allergy and immunology, 31(8), pp. 974-989. Wiley-Blackwell 10.1111/pai.13309

Dalakas, Marinos C; Alexopoulos, Harry; Späth, Peter J (2020). Complement in neurological disorders and emerging complement-targeted therapeutics. Nature reviews. Neurology, 16(11), pp. 601-617. Nature Publishing Group 10.1038/s41582-020-0400-0

Späth, Peter Julius (2018). Essentials of the Production of Safe and Efficacious State-of-the-Art Polyclonal IgG Concentrates. In: Imbach, P. (ed.) Antibody Therapy (pp. 151-173). Springer 10.1007/978-3-319-68038-5_12

Wahn, Volker; Späth, Peter Julius (2018). Historical Aspects of Polyclonal IgG Preparations. In: Imbach, P. (ed.) Antibody Therapy (pp. 121-132). Springer 10.1007/978-3-319-68038-5_10

Späth, Peter Julius (2018). Current IgG Products and Future Perspectives. In: Imbach, P. (ed.) Antibody Therapy (pp. 175-202). Springer 10.1007/978-3-319-68038-5_13

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Späth, Peter Julius; Schneider, Christoph; von Gunten, Stephan (2017). Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations. Archivum immunologiae et therapiae experimentalis, 65(3), pp. 215-231. Springer 10.1007/s00005-016-0422-x

Pilch, Kjara S; Späth, Peter Julius; Yuki, Nobuhiro; Wakerley, Benjamin R (2017). Therapeutic complement inhibition: a promising approach for treatment of neuroimmunological diseases. Expert review of neurotherapeutics, 17(6), pp. 579-591. Expert Reviews 10.1080/14737175.2017.1282821

Lejeune, Alice; Martin, Luise; Santibanez, Sabine; Thee, Stephanie; Gratopp, Alexander; Späth, Peter Julius; Mankertz, Annette; Kallinich, Tilmann; von Bernuth, Horst (2017). Postexposure prophylaxis with intravenous immunoglobulin G prevents infants from getting measles. Acta paediatrica, 106(1), pp. 174-177. Wiley 10.1111/apa.13634

Sudo, Makoto; Miyaji, Kazuki; Späth, Peter Julius; Morita-Matsumoto, Kana; Yamaguchi, Yoshiki; Yuki, Nobuhiro (2016). Polyclonal IgM and IgA block in vitro complement deposition mediated by anti-ganglioside antibodies in autoimmune neuropathies. International immunopharmacology, 40, pp. 11-15. Elsevier 10.1016/j.intimp.2016.08.019

Späth, Peter Julius; Granata, Guido; La Marra, Fabiola; Kuijpers, Taco W.; Quinti, Isabella (2015). On the Dark Side of Therapies with Immunoglobulin Concentrates: The Adverse Events. Frontiers in immunology, 6(11), p. 11. Frontiers Research Foundation 10.3389/fimmu.2015.00011

Kerr, Jacqueline; Quinti, Isabella; Eibl, Martha; Chapel, Helen; Späth, Peter Julius; Sewell, W A Carrock; Salama, Abdulgabar; van Schaik, Ivo N; Kuijpers, Taco W; Peter, Hans-Hartmut (2014). Is dosing of therapeutic immunoglobulins optimal? A review of a three-decade long debate in europe. Frontiers in immunology, 5(629), p. 629. Frontiers Research Foundation 10.3389/fimmu.2014.00629

Sudo, Makoto; Yamaguchi, Yoshiki; Späth, Peter Julius; Matsumoto-Morita, Kana; Ong, Benjamin K.; Shahrizaila, Nortina; Yuki, Nobuhiro (2014). Different IVIG glycoforms affect in vitro inhibition of anti-ganglioside antibody-mediated complement deposition. PLoS ONE, 9(9), e107772. Public Library of Science 10.1371/journal.pone.0107772

Sewell, W. A. Carrock; Kerr, Jacqueline; Behr-Gross, Marie-Emmanuelle; Peter, Hans-Hartmut; Kreuth Ig Working Group, ; Späth, Peter Julius (2014). European consensus proposal for immunoglobulin therapies. European journal of immunology, 44(8), pp. 2207-2214. Wiley-VCH

Späth, Peter Julius; Tamburin, Stefano; Borg, Christian; Caro, Xavier J.; Jann, Stefano; Clark, Alexander J.; Maginelli, Francesca; Sobue, Gen; Werhagen, Lars; Zanetta, Giampietro; Koike, Haruki; Vincent, Angela; Goebel, Andreas (2014). Immunoglobulin g for the treatment of chronic pain: report of an expert workshop. Pain medicine, 15(7), pp. 1072-1082. Wiley-Blackwell 10.1111/pme.12319

Späth, Peter Julius (2014). A novel use of intravenous immunoglobulin is not restricted to complement hypercatabolism because of factor H deficiency. Progress in transplantation, 24(2), p. 120. InnoVision Communications 10.7182/pit2014750

Späth, Peter Julius (2014). Report from a rare diseases event in Targu Mures, Romania. Romanian Review of Laboratory Medicine, 22(3), pp. 397-398. Romanian Association of Medical Laboratories

Späth, Peter Julius (2014). A glance on recent progresses in diagnosis and treatment of primary immunodeficiencies. Romanian Review of Laboratory Medicine, 22(3), pp. 297-309. Romanian Association of Medical Laboratories 10.2478/rrlm-2014-0034

Späth, Peter Julius (2014). Report on Congress Highlights 2013. Congress Report 2013.

Krudewig, J; Baumann, U; Bernuth von, H; Borte, M; Burkhard-Meier, U; Dueckers, G; Foerster-Waldl, E; Franke, K; Habermehl, P; Hönig, M; Kern, W; Kösters, K; Kugel, K; Lehrnbecher, T; Liese, J; Marks, R; Müller, G A; Müller, R; Nadal, D; Peter, H-H; ... (2012). [Interdisciplinary AWMF guideline for the treatment of primary antibody deficiencies]. Klinische Pädiatrie, 224(6), pp. 404-15. Stuttgart: Thieme 10.1055/s-0032-1323837

Charignon, Delphine; Späth, Peter; Martin, Ludovic; Drouet, Christian (2012). Icatibant , the bradykinin B2 receptor antagonist with target to the interconnected kinin systems. Expert opinion on pharmacotherapy, 13(15), pp. 2233-47. London: Informa Healthcare 10.1517/14656566.2012.723692

Späth, Peter J; Lutz, Hans U (2012). Naturally occurring antibodies/autoantibodies in polyclonal immunoglobulin concentrates. Advances in experimental medicine and biology, 750, pp. 239-261. Wien: Springer

Wahn, V; Aberer, W; Eberl, W; Faßhauer, M; Kühne, T; Kurnik, K; Magerl, M; Meyer-Olson, D; Martinez-Saguer, I; Späth, P; Staubach-Renz, P; Kreuz, W (2012). Hereditary angioedema (HAE) in children and adolescents--a consensus on therapeutic strategies. European journal of pediatrics, 171(9), pp. 1339-48. Berlin: Springer 10.1007/s00431-012-1726-4

Yuki, N; Watanabe, H; Nakajima, T; Späth, P J (2011). IVIG blocks complement deposition mediated by anti-GM1 antibodies in multifocal motor neuropathy. Journal of neurology, neurosurgery and psychiatry, 82(1), pp. 87-91. London: BMJ Publishing Group 10.1136/jnnp.2010.205856

Späth, Peter J; Hunziker, Thomas (2011). Will immunoglobulin therapy of autoimmune blistering skin diseases survive the new financial management of inpatients? Dermatology, 222(2), pp. 138-9. Basel: Karger 10.1159/000323006

Delforge, M; Farber, C M; Spath, P; Kaveri, S; Witte, T; Misbah, S A; Hübner, R; Haerynck, F; Latinne, D; Muylle, L; Toungouz, M; Deneys, V; Superior Health Council Belgium, (2011). Recommended indications for the administration of polyclonal immunoglobulin preparations. Acta clinica belgica, 66(5), pp. 346-60. Brussels: Acta clinica belgica 10.2143/ACB.66.5.2062586

Späth, P. J. (2011). Highlights from the 7th C1 Inhibitor Deficiency Workshop, Budapest, Hungary.

Lucas, Mary; Hugh-Jones, Ken; Welby, Angela; Misbah, Siraj; Spaeth, Peter; Chapel, Helen (2010). Immunomodulatory therapy to achieve maximum efficacy: doses, monitoring, compliance, and self-infusion at home. Journal of clinical immunology, 30 Suppl 1, S84-S89. New York, N.Y.: Springer 10.1007/s10875-010-9400-y

Bowen, Tom; Cicardi, Marco; Farkas, Henriette; Bork, Konrad; Longhurst, Hilary J; Zuraw, Bruce; Aygoeren-Pürsün, Emel; Craig, Timothy; Binkley, Karen; Hebert, Jacques; Ritchie, Bruce; Bouillet, Laurence; Betschel, Stephen; Cogar, Della; Dean, John; Devaraj, Ramachand; Hamed, Azza; Kamra, Palinder; Keith, Paul K; Lacuesta, Gina; ... (2010). 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy, asthma & clinical immunology, 6(1), p. 24. Hamilton, Ont.: B.C. Decker Inc.

Wais-Nöcker, B; Stiner, U; Farkas, H; Späth, P; Varga, L (2010). Klinische Facetten des hereditären Angioödems bei einem Schweizer Patientenkollektiv Praxis 99

Fernandez-Cruz, E; Kaveri, S V; Peter, H-H; Durandy, A; Cantoni, N; Quinti, I; Sorensen, R; Bussel, J B; Danieli, M G; Winkelmann, A; Bayry, J; Käsermann, F; Späth, P; Helbert, M; Salama, A; van Schaik, I N; Yuki, N (2009). 6th International Immunoglobulin Symposium: poster presentations. Clinical and experimental immunology, 158 Suppl 1(Suppl 1), pp. 60-67. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2009.04028.x

Wahn, V; Späth, P J (2008). Komplementdefekte, Kinder und Jugendmedizin. Kinder- und Jugendmedizin, 3(2008), pp. 179-184. Stuttgart: Schattauer

Wahn, V; Späth, P (2008). Pathogen safety of immunoglubulin preparations. In: Clinical Use of Immunoglobulins, 1st Edtition (pp. 29-50). Bremen et al.: UNI-MED

Spaeth, P; Wahn, V (2007). Komplementdefekte. Allergologie, 30(2007), pp. 99-105. München-Deisenhofen: Dustri-Verlag

Poehlau, D; Przuntek, H; Sailer, M; Bethke, M; Koehler, J; Koenig, N; Heesen, C; Spaeth, P (2007). Intravenous immunoglobulin in primary and secondary chronic progressive multiple sclerosis: a randomized placebo controlled multicentre study. Multiple sclerosis journal, 13(2007), pp. 1107-1117. London: Sage 10.1177/1352458507078400

Stadler, Beda Martin

Schaub, A; von Gunten, S; Vogel, M; Wymann, S; Rüegsegger, M; Stadler, B M; Spycher, M; Simon, H-U; Miescher, S (2011). Dimeric IVIG contains natural anti-Siglec-9 autoantibodies and their anti-idiotypes. Allergy, 66(8), pp. 1030-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02579.x

von Gunten, Stephan; Vogel, Monique; Schaub, Alexander; Stadler, Beda M; Miescher, Sylvia; Crocker, Paul R; Simon, Hans-Uwe (2007). Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. Journal of allergy and clinical immunology, 119(4), pp. 1005-11. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.01.023

von Gunten, Stephan; Schaub, Alexander; Vogel, Monique; Stadler, Beda M; Miescher, Sylvia; Simon, Hans-Uwe (2006). Immunologic and functional evidence for anti-Siglec-9 autoantibodies in intravenous immunoglobulin preparations. Blood, 108(13), pp. 4255-9. Washington, D.C.: American Society of Hematology 10.1182/blood-2006-05-021568

Starck, Manuel Thierry

Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

Stefan, Nikolas

Stefan, Nikolas; Zimmermann, Martina; Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2014). Novel Prodrug-Like Fusion Toxin with Protease-Sensitive Bioorthogonal PEGylation for Tumor Targeting. Bioconjugate chemistry, 25(12), pp. 2144-2156. American Chemical Society 10.1021/bc500468s

Simon, Manuel; Stefan, Nikolas; Borsig, Lubor; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2014). Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation. Molecular cancer therapeutics, 2(13), pp. 375-385. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0523

Simon, Manuel; Stefan, Nikolas; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2013). Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy. Expert opinion on drug delivery, 10(4), pp. 451-468. Taylor & Francis 10.1517/17425247.2013.759938

Stepanovska Tanturovska, Bisera

Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Pavenstädt, Hermann; Pfeilschifter, Josef; Huwiler, Andrea (2023). Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043267

Stepanovska Tanturovska, Bisera; Manaila, Roxana; Fabbro, Doriano; Huwiler, Andrea (2023). Lipids as Targets for Renal Cell Carcinoma Therapy. International journal of molecular sciences, 24(4) MDPI 10.3390/ijms24043272

Hafizi, Redona; Imeri, Faik; Stepanovska Tanturovska, Bisera; Manaila, Roxana; Schwalm, Stephanie; Trautmann, Sandra; Wenger, Roland H; Pfeilschifter, Josef; Huwiler, Andrea (2022). Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells. International journal of molecular sciences, 23(11) MDPI 10.3390/ijms23115882

Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Imeri, Faik; Homann, Thomas; Kleuser, Burkhard; Stark, Holger; Huwiler, Andrea (2021). ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo. Molecules, 26(17) Molecular Diversity Preservation International MDPI 10.3390/molecules26175134

Imeri, Faik; Stepanovska Tanturovska, Bisera; Schwalm, Stephanie; Saha, Sarbari; Zeng-Brouwers, Jinyang; Pavenstädt, Herrmann; Pfeilschifter, Josef; Schaefer, Liliana; Huwiler, Andrea (2021). Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice. Matrix biology, 98, pp. 32-48. Elsevier 10.1016/j.matbio.2021.05.003

Imeri, Faik; Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Schwalm, Stephanie; Pfeilschifter, Josef; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2021). Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis. Neuropharmacology, 186, p. 108464. Elsevier 10.1016/j.neuropharm.2021.108464

Stepanovska, Bisera; Zivkovic, Aleksandra; Enzmann, Gaby; Tietz, Silvia; Homann, Thomas; Kleuser, Burkhard; Engelhardt, Britta; Stark, Holger; Huwiler, Andrea (2020). Morpholino Analogues of Fingolimod as Novel and Selective S1P1 Ligands with In Vivo Efficacy in a Mouse Model of Experimental Antigen-Induced Encephalomyelitis. International journal of molecular sciences, 21(18), pp. 1-17. MDPI 10.3390/ijms21186463

Stepanovska, Bisera; Huwiler, Andrea (2020). Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases. Pharmacological research, 154, p. 104170. Elsevier 10.1016/j.phrs.2019.02.009

Stepanovska, Bisera; Lange, Antonia I; Schwalm, Stephanie; Pfeilschifter, Josef; Coldewey, Sina M; Huwiler, Andrea (2020). Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041240

Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

Stieger, Pia

Reinhardt, Didier; Pesce, Eva-Rachele; Stieger, Pia; Mandel, Therese; Baltensperger, Kurt; Bennett, Malcolm; Traas, Jan; Friml, Jiří; Kuhlemeier, Cris (2003). Regulation of phyllotaxis by polar auxin transport. Nature, 426(6964), pp. 255-260. Macmillan Journals Ltd. 10.1038/nature02081

Stojkov, Darko

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2024). NETs: Important players in asthma? Journal of allergy and clinical immunology, 153(1), pp. 100-102. Elsevier 10.1016/j.jaci.2023.09.031

Peng, Shuang; Gao, Jian; Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2023). Established and emerging roles for mitochondria in neutrophils. Immunological reviews, 314(1), pp. 413-426. Wiley-Blackwell 10.1111/imr.13158

Hosseini, Aref; Stojkov, Darko; Fettrelet, Timothée; Bilyy, Rostyslav; Yousefi, Shida; Simon, Hans-Uwe (2023). Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032646

Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517

Gigon, Lea; Fettrelet, Timothée; Miholic, Marta; McLeish, Kenneth R; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2023). Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. Frontiers in immunology, 14(1272699), p. 1272699. Frontiers Research Foundation 10.3389/fimmu.2023.1272699

Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14 Frontiers Research Foundation 10.3389/fimmu.2023.1331151

Peng, Shuang; Stojkov, Darko; Gao, Jian; Oberson, Kevin; Latzin, Philipp; Casaulta, Carmen; Yousefi, Shida; Simon, Hans-Uwe (2022). Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils. PLoS biology, 20(9), e3001794. Public Library of Science 10.1371/journal.pbio.3001794

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113

Frangež, Živa; Fernández-Marrero, Yuniel; Stojkov, Darko; Seyed Jafari, S. Morteza; Hunger, Robert E.; Djonov, Valentin; Riether, Carsten; Simon, Hans-Uwe (2020). BIF-1 inhibits both mitochondrial and glycolytic ATP production: its downregulation promotes melanoma growth. Oncogene, 39(26), pp. 4944-4955. Springer Nature 10.1038/s41388-020-1339-8

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Surmiak, Marcin; Gielicz, Anna; Stojkov, Darko; Szatanek, Rafał; Wawrzycka-Adamczyk, Katarzyna; Yousefi, Shida; Simon, Hans-Uwe; Sanak, Marek (2020). LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis. Journal of lipid research, 61(1), pp. 1-9. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M092072

Gjuroski, Ilche; Girousi, Eleftheria; Meyer, Christoph; Hertig, Damian; Stojkov, Darko; Fux, Michaela; Schnidrig, Nicolas; Bucher, Jan; Pfister, Sara; Sauser, Luca; Simon, Hans-Uwe; Vermathen, Peter; Furrer, Julien; Vermathen, Martina (2019). Evaluation of polyvinylpyrrolidone and block copolymer micelle encapsulation of serine chlorin e6 and chlorin e4 on their reactivity towards albumin and transferrin and their cell uptake. Journal of controlled release, 316, pp. 150-167. Elsevier 10.1016/j.jconrel.2019.10.010

Yadav, Sandeep Kumar; Stojkov, Darko; Feigelson, Sara W; Roncato, Francesco; Simon, Hans-Uwe; Yousefi, Shida; Alon, Ronen (2019). Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration. Journal of leukocyte biology, 105(4), pp. 755-766. Society for Leukocyte Biology 10.1002/JLB.3A1118-437RR

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Stojkov, Darko (2016). Actin polymerization and its glutathionylation are required for NET formation (Submitted). (Dissertation, Institute of Pharmacology, Faculty of Medicine of the University of Bern)

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Storni, Federico Lorenzo

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Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

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Tobler, Andreas

Britschgi, Adrian; Simon, Hans-Uwe; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2010). Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2. British journal of haematology, 149(1), pp. 55-64. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.08040.x

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Démoulins, Thomas; Schulze, Kai; Ebensen, Thomas; Techakriengkrai, Navapon; Nedumpun, Teerawut; Englezou, Pavlos C; Gerber, Markus; Hlushchuk, Ruslan; Toledo, Darien; Djonov, Valentin; von Gunten, Stephan; McCullough, Kenneth C; Liniger, Matthias; Guzmán, Carlos A; Suradhat, Sanipa; Ruggli, Nicolas (2023). Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases. Nanomedicine : nanotechnology, biology, and medicine, 49(102655), p. 102655. Elsevier 10.1016/j.nano.2023.102655

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Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2019). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. Cell death and differentiation, 26(6), pp. 1048-1061. Nature Publishing Group 10.1038/s41418-018-0182-8

Tschan, Mario

Seiler, Kristina; Humbert, Magali; Minder, Petra; Mashimo, Iris; Schläfli, Anna M; Krauer, Deborah; Federzoni, Elena A; Vu, Bich; Moresco, James J; Yates, John R; Sadowski, Martin C; Radpour, Ramin; Kaufmann, Thomas; Sarry, Jean-Emmanuel; Dengjel, Joern; Tschan, Mario P; Torbett, Bruce E (2022). Hexokinase 3 enhances myeloid cell survival via non-glycolytic functions. Cell death & disease, 13(5), p. 448. Springer Nature 10.1038/s41419-022-04891-w

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

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Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15

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He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

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Ueki, Yasushi

Rexhaj, Emrush; Bär, Sarah; Soria, Rodrigo; Ueki, Yasushi; Häner, Jonas D; Otsuka, Tatsuhiko; Kavaliauskaite, Raminta; Siontis, George CM; Stortecky, Stefan; Shibutani, Hiroki; Spirk, David; Engstrøm, Thomas; Lang, Irene; Morf, Laura; Ambühl, Maria; Windecker, Stephan; Losdat, Sylvain; Koskinas, Konstantinos C; Räber, Lorenz (2024). Effects of alirocumab on endothelial function and coronary atherosclerosis in myocardial infarction: A PACMAN-AMI randomized clinical trial substudy. (In Press). Atherosclerosis, 392, p. 117504. Elsevier 10.1016/j.atherosclerosis.2024.117504

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Riebenfeld, Daniela; Spirk, David; Mathis, Alexandra; Villiger, Lukas; Gerber, Philipp A; Gasser, Urs Erwin; Lehmann, Roger (2015). Treatment intensification with insulin glargine in patients with inadequately controlled type 2 diabetes improves glycaemic control with a high treatment satisfaction and no weight gain. Swiss medical weekly, 145, w14114. EMH Schweizerischer Ärzteverlag 10.4414/smw.2015.14114

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Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

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Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

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Yawalkar, Nikhil

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

Simon, Dagmar; Wittwer, Jennifer; Kostylina, Ganna; Buettiker, Urs; Simon, Hans-Uwe; Yawalkar, Nikhil (2008). Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema. Journal of allergy and clinical immunology, 122(2), pp. 423-4. St. Louis, Mo.: Mosby 10.1016/j.jaci.2008.06.010

Simon, Dagmar; Hösli, Susanne; Kostylina, Ganna; Yawalkar, Nikhil; Simon, Hans-Uwe (2008). Anti-CD20 (rituximab) treatment improves atopic eczema. Journal of allergy and clinical immunology, 121(1), pp. 122-8. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.016

Hassan, Akmal S; Simon, Dagmar; Simon, Hans-Uwe; Braathen, Lasse R; Yawalkar, Nikhil (2007). Efalizumab-associated papular psoriasis. Archives of dermatology, 143(7), pp. 900-6. Chicago, Ill.: American Medical Association 10.1001/archderm.143.7.900

Yousefi, Shida

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. (In Press). Clinical and translational gastroenterology Wolters Kluwer Health 10.14309/ctg.0000000000000664

Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2024). NETs: Important players in asthma? Journal of allergy and clinical immunology, 153(1), pp. 100-102. Elsevier 10.1016/j.jaci.2023.09.031

Gigon, Lea; Fettrelet, Timothée; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2023). Eosinophils from A to Z. Allergy, 78(7), pp. 1810-1846. Wiley 10.1111/all.15751

Peng, Shuang; Gao, Jian; Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2023). Established and emerging roles for mitochondria in neutrophils. Immunological reviews, 314(1), pp. 413-426. Wiley-Blackwell 10.1111/imr.13158

Hosseini, Aref; Stojkov, Darko; Fettrelet, Timothée; Bilyy, Rostyslav; Yousefi, Shida; Simon, Hans-Uwe (2023). Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032646

Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517

Gigon, Lea; Fettrelet, Timothée; Miholic, Marta; McLeish, Kenneth R; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2023). Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. Frontiers in immunology, 14(1272699), p. 1272699. Frontiers Research Foundation 10.3389/fimmu.2023.1272699

Bürgler, Christina; Dutoit, Danielle; Radonjic-Hoesli, Susanne; Thormann, Kathrin; Lehmann, Mathias; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2023). Dupilumab normalizes correlates of lysosomal function in atopic dermatitis (In Press). JEADV Clinical Practice Wiley 10.1002/jvc2.307

Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14 Frontiers Research Foundation 10.3389/fimmu.2023.1331151

Peng, Shuang; Stojkov, Darko; Gao, Jian; Oberson, Kevin; Latzin, Philipp; Casaulta, Carmen; Yousefi, Shida; Simon, Hans-Uwe (2022). Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils. PLoS biology, 20(9), e3001794. Public Library of Science 10.1371/journal.pbio.3001794

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. Allergy, 77(8), pp. 2520-2533. Wiley 10.1111/all.15233

Fallegger, Angela; Priola, Martina; Artola-Borán, Mariela; Núñez, Nicolás Gonzalo; Wild, Sebastian; Gurtner, Alessandra; Becher, Burkhard; Yousefi, Shida; Simon, Hans-Uwe; Arnold, Isabelle C; Müller, Anne (2022). TGF-β production by eosinophils drives the expansion of peripherally induced neuropilin- RORγt+ regulatory T-cells during bacterial and allergen challenge. Mucosal immunology, 15(3), pp. 504-514. Springer Nature 10.1038/s41385-022-00484-0

Klapan, Kim; Simon, Dagmar; Karaulov, Alexander; Gomzikova, Marina; Rizvanov, Albert; Yousefi, Shida; Simon, Hans-Uwe (2022). Autophagy and Skin Diseases. Frontiers in Pharmacology, 13, p. 844756. Frontiers 10.3389/fphar.2022.844756

Artola-Borán, Mariela; Fallegger, Angela; Priola, Martina; Jeske, Rima; Waterboer, Tim; Dohlman, Anders B; Shen, Xiling; Wild, Sebastian; He, Jiazhuo; Levesque, Mitchell P; Yousefi, Shida; Simon, Hans-Uwe; Cheng, Phil F; Müller, Anne (2022). Mycobacterial infection aggravates Helicobacter pylori-induced gastric preneoplastic pathology by redirection of de novo induced Treg cells. Cell reports, 38(6), p. 110359. Cell Press 10.1016/j.celrep.2022.110359

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Ackermann, Maximilian; Anders, Hans-Joachim; Bilyy, Rostyslav; Bowlin, Gary L; Daniel, Christoph; De Lorenzo, Rebecca; Egeblad, Mikala; Henneck, Timo; Hidalgo, Andrés; Hoffmann, Markus; Hohberger, Bettina; Kanthi, Yogendra; Kaplan, Mariana J; Knight, Jason S; Knopf, Jasmin; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; Mahajan, Aparna; Manfredi, Angelo A; ... (2021). Patients with COVID-19: in the dark-NETs of neutrophils. Cell death and differentiation, 28(11), pp. 3125-3139. Springer Nature 10.1038/s41418-021-00805-z

Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003

Wang, Xiaoliang; Avsec, Damjan; Obreza, Aleš; Yousefi, Shida; Mlinarič-Raščan, Irena; Simon, Hans-Uwe (2021). A Putative Serine Protease is Required to Initiate the RIPK3-MLKL-Mediated Necroptotic Death Pathway in Neutrophils. Frontiers in Pharmacology, 11, p. 614928. Frontiers 10.3389/fphar.2020.614928

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706

Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113

Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Surmiak, Marcin; Gielicz, Anna; Stojkov, Darko; Szatanek, Rafał; Wawrzycka-Adamczyk, Katarzyna; Yousefi, Shida; Simon, Hans-Uwe; Sanak, Marek (2020). LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis. Journal of lipid research, 61(1), pp. 1-9. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M092072

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

Yadav, Sandeep Kumar; Stojkov, Darko; Feigelson, Sara W; Roncato, Francesco; Simon, Hans-Uwe; Yousefi, Shida; Alon, Ronen (2019). Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration. Journal of leukocyte biology, 105(4), pp. 755-766. Society for Leukocyte Biology 10.1002/JLB.3A1118-437RR

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

Arnold, Isabelle C; Artola-Borán, Mariela; Tallón de Lara, Paulino; Kyburz, Andreas; Taube, Christian; Ottemann, Karen; van den Broek, Maries; Yousefi, Shida; Simon, Hans-Uwe; Müller, Anne (2018). Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. Journal of experimental medicine, 215(8), pp. 2055-2072. Rockefeller University Press 10.1084/jem.20172049

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Gevaert, Elien; Yousefi, Shida; Bachert, Claus; Simon, Hans-Uwe (2018). Reply. The Journal of allergy and clinical immunology, 141(3), pp. 1164-1165. Elsevier 10.1016/j.jaci.2017.05.048

Wang, Xiaoliang; Yousefi, Shida; Simon, Hans-Uwe (2018). Necroptosis and neutrophil-associated disorders. Cell death & disease, 9(2), p. 111. Nature Publishing Group 10.1038/s41419-017-0058-8

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Vicari, Alain P; Schoepfer, Alain M; Meresse, Bertrand; Goffin, Laurence; Léger, Olivier; Josserand, Soheila; Guégan, Nicolas; Yousefi, Shida; Straumann, Alex; Cerf-Bensussan, Nadine; Simon, Hans-Uwe; Chvatchko, Yolande (2017). Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. mAbs, 9(6), pp. 927-944. Taylor & Francis 10.1080/19420862.2017.1332553

Gevaert, Elien; Zhang, Nan; Krysko, Olga; Lan, Feng; Holtappels, Gabriële; De Ruyck, Natalie; Nauwynck, Hans; Yousefi, Shida; Simon, Hans-Uwe; Bachert, Claus (2017). Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in severe airway inflammation. The Journal of allergy and clinical immunology, 139(6), 1849-1860.e6. Elsevier 10.1016/j.jaci.2017.01.019

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Simon, Hans-Uwe; Yousefi, Shida; Simon, Dagmar (2016). Basophils can form extracellular DNA traps independent of a functional NADPH oxidase. In: Maurer, Markus; Behrendt, Heidrum (eds.) Allergies: Current challenges and solutions. Proceedings of the 30th Symposium of the Collegium Internationale Allergologicum (CIA) (pp. 67-70). Ospedaletto (Pisa): Pacini editore Medicina

Yousefi, Shida; Simon, Hans-Uwe (2016). NETosis - Does It Really Represent Nature's "Suicide Bomber"? Frontiers in immunology, 7(328), p. 328. Frontiers Research Foundation 10.3389/fimmu.2016.00328

Stojkov, Darko (2016). Actin polymerization and its glutathionylation are required for NET formation (Submitted). (Dissertation, Institute of Pharmacology, Faculty of Medicine of the University of Bern)

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Hurrell, Benjamin P; Schuster, Steffen; Grün, Eva; Coutaz, Manuel; Williams, Roderick A; Held, Werner; Malissen, Bernard; Malissen, Marie; Yousefi, Shida; Simon, Hans-Uwe; Müller, Andreas J; Tacchini-Cottier, Fabienne (2015). Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. PLoS pathogens, 11(5), e1004929. Public Library of Science 10.1371/journal.ppat.1004929

Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570

Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Eveline; Schmid, Ines; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S and Simon, Hans-Uwe (2015). Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular cell, 57(6), pp. 1011-1021. Cell Press 10.1016/j.molcel.2015.01.026

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2014). Eosinophil extracellular traps: potential role(s) in eosinophilic diseases. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from Mechanisms to Cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 87-89). Pisa: Pacini Editore S.p.A.

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2014). Eosinophil extracellular trap formation in response to thymic stromal lymphopoietin stimulation. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from mechanisms to cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 83-86). Pisa: Pacini Editore

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2013). Extracellular DNA traps in allergic, infectzious, and autoimmune diseases. Allergy, 68(4), pp. 409-416. Wiley-Blackwell 10.1111/all.12111

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200

Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2012). Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease. Current opinion in immunology, 24(6), pp. 736-9. Kidlington, UK: Elsevier 10.1016/j.coi.2012.08.010

Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x

Kerstan, A; Simon, H-U; Yousefi, S; Leverkus, M (2012). Extensive accumulation of eosinophil extracellular traps in bullous delayed-pressure urticaria: a pathophysiological link? British journal of dermatology, 166(5), pp. 1151-2. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2012.10848.x

Simon, HU; Yousefi, S (2012). Mitochondrial DNA released by eosinophils contributes to innate immunity. Pisa: Pacini Editore S.p.A.

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Mihalache, Cristina C; Yousefi, Shida; Conus, Sébastien; Villiger, Peter M; Schneider, E Marion; Simon, Hans-Uwe (2011). Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events. Journal of immunology, 186(11), pp. 6532-42. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1004055

Dworski, Ryszard; Simon, Hans-Uwe; Hoskins, Aimee; Yousefi, Shida (2011). Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways. Journal of allergy and clinical immunology, 127(5), pp. 1260-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.12.1103

Simon, Dagmar; Hoesli, Susanne; Roth, Nina; Staedler, Simon; Yousefi, Shida; Simon, Hans-Uwe (2011). Eosinophil extracellular DNA traps in skin diseases. Journal of allergy and clinical immunology, 127(1), pp. 194-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.11.002

El-Hashim, Ahmed; Yousefi, Shida; Edafiogho, Ivan; Raghupathy, Raj; Yousif, Mariam; Simon, Hans-Uwe (2010). Anti-inflammatory and immunosuppressive effects of the enaminone E121. European journal of pharmacology, 632(1-3), pp. 73-78. Amsterdam: Elsevier 10.1016/j.ejphar.2009.12.004

Schmidt-Mende, Jan; Geering, Barbara; Yousefi, Shida; Simon, Hans-Uwe (2010). Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells. European journal of immunology, 40(2), pp. 525-9. Weinheim: Wiley-VCH 10.1002/eji.200939556

Salemi, S; Yousefi, S; Simon, D; Schmid, I; Moretti, L; Scapozza, L; Simon, H-U (2009). A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. Allergy, 64(6), pp. 913-8. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.01943.x

Yousefi, S; Mihalache, C; Kozlowski, E; Schmid, I; Simon, H U (2009). Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps. Cell death and differentiation, 16(11), pp. 1438-44. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.96

Daryadel, Arezoo; Yousefi, Shida; Troi, David; Schmid, Inès; Schmidt-Mende, Jan; Mordasini, Carlo; Dahinden, Clemens A; Ziemiecki, Andrew; Simon, Hans-Uwe (2009). RhoH/TTF negatively regulates leukotriene production in neutrophils. Journal of immunology, 182(10), pp. 6527-32. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803846

Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cells of the blood. Biochimica and biophysica acta - molecular and cell biology of lipids, 1793(9), pp. 1461-4. New York, N.Y.: Elsevier 10.1016/j.bbamcr.2008.12.023

Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cancer and chemotherapy. Results and problems in cell differentiation, 49, pp. 183-190. Berlin: Springer

Simon, Dagmar; Salemi, Souzan; Yousefi, Shida; Simon, Hans-Uwe (2008). Primary resistance to imatinib in Fip1-like 1-platelet-derived growth factor receptor alpha-positive eosinophilic leukemia. Journal of allergy and clinical immunology, 121(4), pp. 1054-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.027

Federzoni, Elena; Gordon, Grace; Müller, Stefan; Schmid, Inès; Simon, Hans-Uwe; Yousefi, Shida (2008). Expression of CD95 on mature leukocytes of MRL/lpr mice after transplantation of genetically modified bone marrow stem cells. Immunology letters, 117(1), pp. 45-9. Amsterdam: Elsevier 10.1016/j.imlet.2007.11.019

Kuhn, A; Leupin, N; Fey, M.F.; Yousefi, S; Simon, H.U. (2008). Leukaemia cell lines are robust in vitro models - response to MacLeod & Drexler. British journal of haematology(142), pp. 138-141. Oxford: Wiley-Blackwell

Yousefi, Shida; Gold, Jeffrey A; Andina, Nicola; Lee, James J; Kelly, Ann M; Kozlowski, Evelyne; Schmid, Inès; Straumann, Alex; Reichenbach, Janine; Gleich, Gerald J; Simon, Hans-Uwe (2008). Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nature medicine, 14(9), pp. 949-53. New York, N.Y.: Nature Publishing Group 10.1038/nm.1855

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Yousefi, Shida; Simon, Hans-Uwe (2007). Apoptosis regulation by autophagy gene 5. Critical reviews in oncology, hematology, 63(3), pp. 241-4. Boca Raton, Fla.: Elsevier 10.1016/j.critirevonc.2007.06.005

Tsilimparis, N; Alevizakos, P; Yousefi, S; Hanack, U; Im Spring, B; Blank, B; Rückert, R I (2007). [Endovascular therapy of an abdominal aortic aneurysm in a renal transplant recipient]. Zentralblatt für Chirurgie, 132(3), 220-5; discussion 225-6. Stuttgart: Thieme 10.1055/s-2007-981162

White, Amy M; Banovac, Filip; Yousefi, Shadi; Slack, Rebecca S; Spies, James B (2007). Uterine fibroid embolization: the utility of aortography in detecting ovarian artery collateral supply. Radiology, 244(1), pp. 291-8. Oak Brook, Ill.: Radiological Society of North America RSNA 10.1148/radiol.2441060796

Tsilimparis, Nikolaos; Hanack, Ulrich; Yousefi, Sharom; Alevizakos, Pavlos; Rückert, Ralph I (2007). Cystic adventitial disease of the popliteal artery: an argument for the developmental theory. Journal of vascular surgery, 45(6), pp. 1249-52. Amsterdam: Elsevier 10.1016/j.jvs.2007.01.051

Yousefi, S; Simon, HU (2007). Taxol Therapy revisited. Blood, 110(2007), p. 3492. Washington, D.C.: American Society of Hematology 10.1182/blood-2007-08-105486

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Daryadel, Arezoo; Grifone, Remo Filippo; Simon, Hans-Uwe; Yousefi, Shida (2006). Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha. Journal of biological chemistry, 281(37), pp. 27653-61. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M604051200

Vassina, Ekatherina M; Yousefi, Shida; Simon, Dagmar; Zwicky, Caroline; Conus, Sébastien; Simon, Hans-Uwe (2006). cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. European journal of immunology, 36(7), pp. 1975-84. Weinheim: Wiley-VCH 10.1002/eji.200635943

Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692

Salemi, Souzan; Yousefi, Shida; Eblé, Andrée; Deladoëy, Johnny; Mullis, Primus E (2006). Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis. Hormone research, 65(3), pp. 132-41. Basel: Karger 10.1159/000091607

Nachbur, Ueli; Kassahn, Daniela; Yousefi, Shida; Legler, Daniel F; Brunner, Thomas (2006). Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts. Blood, 107(7), pp. 2790-6. Washington, D.C.: American Society of Hematology 10.1182/blood-2005-07-2744

Baumann, Ralf; Yousefi, Shida; Simon, Dagmar; Russmann, Stefan; Mueller, Christoph; Simon, Hans-Uwe (2004). Functional expression of CD134 by neutrophils. European journal of immunology, 34(8), pp. 2268-2275. Wiley-VCH 10.1002/eji.200424863

Altznauer, Frank; Martinelli, Sibylla; Yousefi, Shida; Thürig, Christine; Schmid, Inès; Conway, Edward M; Schöni, Martin H; Vogt, Peter; Mueller, Christoph; Fey, Martin F; Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2004). Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils. The Journal of experimental medicine, 199(10), pp. 1343-1354. Rockefeller Univ. Press 10.1084/jem.20032033

Zanchin, Christian

Räber, Lorenz; Ueki, Yasushi; Otsuka, Tatsuhiko; Losdat, Sylvain; Häner, Jonas D; Lonborg, Jacob; Fahrni, Gregor; Iglesias, Juan F; van Geuns, Robert-Jan; Ondracek, Anna S; Radu Juul Jensen, Maria D; Zanchin, Christian; Stortecky, Stefan; Spirk, David; Siontis, George C; Saleh, Lanja; Matter, Christian M; Daemen, Joost; Mach, François; Heg, Dik; ... (2022). Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial. JAMA - the journal of the American Medical Association, 327(18), pp. 1771-1781. American Medical Association 10.1001/jama.2022.5218

Zanchin, Christian; Koskinas, Konstantinos C.; Ueki, Yasushi; Losdat, Sylvain; Häner, Jonas; Bär, Sarah; Otsuka, Tatsuhiko; Inderkum, Andrea; Jensen, Maria Radu Juul; Lonborg, Jacob; Fahrni, Gregor; Ondracek, Anna S; Daemen, Joost; van Geuns, Robert-Jan; Iglesias, Juan; Matter, Christian M; Spirk, David; Juni, Peter; Mach, Francois; Heg, Dik; ... (2021). Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial. American Heart Journal, 238, pp. 33-44. Elsevier 10.1016/j.ahj.2021.04.006

Zanchin, Christian; Ueki, Yasushi; Losdat, Sylvain; Fahrni, Gregor; Daemen, Joost; Ondracek, Anna S; Häner, Jonas D.; Stortecky, Stefan; Otsuka, Tatsuhiko; Siontis, George C.M.; Rigamonti, Fabio; Radu, Maria; Spirk, David; Kaiser, Christoph; Engstrom, Thomas; Lang, Irene; Koskinas, Konstantinos C.; Räber, Lorenz (2021). In vivo relationship between near-infrared spectroscopy-detected lipid-rich plaques and morphological plaque characteristics by optical coherence tomography and intravascular ultrasound: a multimodality intravascular imaging study. European heart journal - cardiovascular imaging, 22(7), pp. 824-834. Oxford University Press 10.1093/ehjci/jez318

Zangemeister-Wittke, Uwe

Merten, Hannes; Brandl, Fabian; Zimmermann, Martina; Schaefer, Jonas V; Irpinio, Linda; Sand, Kine M K; Nilsen, Jeannette; Andersen, Jan Terje; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2021). Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling. European journal of pharmaceutics and biopharmaceutics, 167, pp. 104-113. Elsevier 10.1016/j.ejpb.2021.07.011

Brandl, Fabian; Busslinger, Sarah; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2020). Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life. Journal of controlled release, 327, pp. 186-197. Elsevier 10.1016/j.jconrel.2020.08.004

Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041396

Brandl, Fabian; Merten, Hannes; Zimmermann, Martina; Béhé, Martin; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins. Journal of controlled release, 307, pp. 379-392. Elsevier 10.1016/j.jconrel.2019.06.030

Lorenzer, Cornelia; Streußnig, Sonja; Tot, Emilia; Winkler, Anna-Maria; Merten, Hannes; Brandl, Fabian; Sayers, Edward J; Watson, Peter; Jones, Arwyn T; Zangemeister-Wittke, Uwe; Plückthun, Andreas; Winkler, Johannes (2019). Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing. European journal of pharmaceutics and biopharmaceutics, 141, pp. 37-50. Elsevier 10.1016/j.ejpb.2019.05.015

Merten, Hannes; Schaefer, Jonas V; Brandl, Fabian; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2019). Facile Site-Specific Multiconjugation Strategies in Recombinant Proteins Produced in Bacteria. Methods in molecular biology, 2033, pp. 253-273. Springer 10.1007/978-1-4939-9654-4_17

Blanchard, Olivier; Stepanovska, Bisera; Starck, Manuel Thierry; Erhardt, Martin; Römer, Isolde; Meyer Zu Heringdorf, Dagmar; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2018). Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells. International journal of molecular sciences, 19(5) Molecular Diversity Preservation International MDPI 10.3390/ijms19051498

Huwiler, Andrea; Zangemeister-Wittke, Uwe (2018). The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: recent findings and new perspectives. Pharmacology & therapeutics, 185, pp. 34-49. Elsevier 10.1016/j.pharmthera.2017.11.001

Graumann, Rebecca; Di Capua, Gabriella A; Oyarzún, Juan E; Vásquez, Marcos A; Liao, Christine; Brañes, Jorge A; Roa, Iván; Casanello, Paola; Corvalán, Alejandro H; Owen, Gareth I; Delgado, Iris; Zangemeister-Wittke, Uwe; Ziegler, Annemarie (2017). Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer. PLoS ONE, 12(5), e0177244. Public Library of Science 10.1371/journal.pone.0177244

Filipenko, Iuliia; Schwalm, Stephanie; Reali, Luca; Pfeilschifter, Josef; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2016). Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(11), pp. 1840-1851. Elsevier 10.1016/j.bbalip.2016.09.005

Simon, Hans-Uwe; Zangemeister-Wittke, Uwe (2016). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer. Heidelberg: Springer

Filipenko, Iuliia; Huwiler, Andrea (2016). The role of the S1P3 receptor in inflammation-associated proliferative disorders (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Merten, Hannes; Brandl, Fabian; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2015). Antibody-Drug Conjugates for Tumor Targeting-Novel Conjugation Chemistries and the Promise of non-IgG Binding Proteins. Bioconjugate chemistry, 26(11), pp. 2176-2185. American Chemical Society 10.1021/acs.bioconjchem.5b00260

Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

Pastukhov, Oleksandr; Schalm, Stephanie; Zangemeister-Wittke, Uwe; Fabbro, Doriano; Bornancin, Frederic; Japtok, Lukasz; Kleuser, Burkhrad; Pfeilschifter, Josef; Huwiler, Andrea (2014). The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death. British journal of pharmacology, 171(24), pp. 5829-5844. Wiley-Blackwell 10.1111/bph.12886

Stefan, Nikolas; Zimmermann, Martina; Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2014). Novel Prodrug-Like Fusion Toxin with Protease-Sensitive Bioorthogonal PEGylation for Tumor Targeting. Bioconjugate chemistry, 25(12), pp. 2144-2156. American Chemical Society 10.1021/bc500468s

Thangaiyan, Rabi; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). AMR-Me inhibits PI3K/Akt signaling in hormone-dependent MCF-7 breast cancer cells and inactivates NF-κB in hormone-independent MDA-MB-231 cells. Molecular carcinogenesis, 53(7), pp. 578-588. Wiley 10.1002/mc.22012

Simon, Manuel; Stefan, Nikolas; Borsig, Lubor; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2014). Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation. Molecular cancer therapeutics, 2(13), pp. 375-385. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-13-0523

Pastukhov, Oleksandr; Schalm, Stephanie; Römer, Isolde; Pfeilschifter, Josef; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts. Cellular physiology and biochemistry, 34(1), pp. 119-133. Karger 10.1159/000362989

Wojtalla, Anna; Fischer, Barbara; Kotelevets, Nataliya; Mauri, Francesco A; Sobek, Jens; Rehrauer, Hubert; Wotzkow, Carlos; Tschan, Mario P; Seckl, Michael J; Zangemeister-Wittke, Uwe; Arcaro, Alexandre (2013). Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clinical cancer research, 19(1), pp. 96-105. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-1138

Simon, Manuel; Frey, Raphael; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2013). Orthogonal assembly of a designed ankyrin repeat protein-cytotoxin conjugate with a clickable serum albumin module for half-life extension. Bioconjugate chemistry, 24(11), pp. 1955-1986. American Chemical Society 10.1021/bc4004102

Simon, Manuel; Stefan, Nikolas; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2013). Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy. Expert opinion on drug delivery, 10(4), pp. 451-468. Taylor & Francis 10.1517/17425247.2013.759938

Kotelevets, Nataliya; Fabbro, Doriano; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2012). Targeting sphingosine kinase 1 in carcinoma cells decreases proliferation and survival by compromising PKC activity and cytokinesis. PLoS ONE, 7(6), e39209. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0039209

Heine, Markus; Freund, Barbara; Nielsen, Peter; Jung, Caroline; Reimer, Rudolph; Hohenberg, Heinrich; Zangemeister-Wittke, Uwe; Wester, Hans-Juergen; Lüers, Georg H; Schumacher, Udo (2012). High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes. PLoS ONE, 7(5), e36258. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0036258

Simon, Manuel; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2012). Facile double-functionalization of designed ankyrin repeat proteins using click and thiol chemistries. Bioconjugate chemistry, 23(2), pp. 279-86. Washington, D.C.: American Chemical Society 10.1021/bc200591x

Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2012). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer (pp. 2437-2440). Heidelberg: Springer-Verlage 10.1007/978-3-642-16483-5

Patricia, Martin-Killias; Stefan, Nikolas; Rothschild, Sacha; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2011). A novel fusion toxin derived from an EpCAM-specific designed ankyrin repeat protein has potent antitumor activity. Clinical cancer research, 17(1), pp. 100-10. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-10-1303

Huwiler, Andrea; Bourquin, Florence; Kotelevets, Nataliya; Pastukhov, Oleksandr; Capitani, Guido; Grütter, Markus G; Zangemeister-Wittke, Uwe (2011). A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders. PLoS ONE, 6(8), e22436. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022436

Huwiler, Andrea; Kotelevets, Nataliya; Xin, Cuiyan; Pastukhov, Oleksandr; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe (2011). Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage. British journal of pharmacology, 162(2), pp. 532-43. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.01053.x

Stefan, Nikolas; Martin-Killias, Patricia; Wyss-Stoeckle, Sascha; Honegger, Annemarie; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2011). DARPins recognizing the tumor-associated antigen EpCAM selected by phage and ribosome display and engineered for multivalency. Journal of molecular biology, 413(4), pp. 826-43. Amsterdam: Elsevier 10.1016/j.jmb.2011.09.016

Lange, Annika; Gustke, Heike; Glassmeier, Günter; Heine, Markus; Zangemeister-Wittke, Uwe; Schwarz, Jürgen R; Schumacher, Udo; Lange, Tobias (2011). Neuronal differentiation by indomethacin and IBMX inhibits proliferation of small cell lung cancer cells in vitro. Lung cancer, 74(2), pp. 178-87. Amsterdam: Elsevier 10.1016/j.lungcan.2011.03.017

Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2009). Myelosuppression. In: Schwab, Manfred (ed.) Encyclopedia of Cancer, 2nd Edition (pp. 2008-2010). Heidelberg: Springer Verlag 10.1007/978-3-540-47648-1_3940

Winkler, Johannes; Martin-Killias, Patricia; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2009). EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins. Molecular cancer therapeutics, 8(9), pp. 2674-83. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-09-0402

Sodeur, Stephan; Ullrich, Sebastian; Gustke, Heike; Zangemeister-Wittke, Uwe; Schumacher, Udo (2009). Increased numbers of spontaneous SCLC metastasis in absence of NK cells after subcutaneous inoculation of different SCLC cell lines into pfp/rag2 double knock out mice. Cancer letters, 282(2), pp. 146-51. Amsterdam: Elsevier 10.1016/j.canlet.2009.03.005

Mousavi-Shafaei, Parisa; Ziaee, Abed-Ali; Zangemeister-Wittke, Uwe (2009). Increased cytotoxicity of cisplatin in SK-MEL 28 melanoma cells upon down-regulation of melanoma inhibitor of apoptosis protein Iran Biomed J

Marinov, Marin; Ziogas, Algirdas; Pardo, Olivier E; Tan, Liwen Terence; Dhillon, Tony; Mauri, Francesco A; Lane, Heidi A; Lemoine, Nicholas R; Zangemeister-Wittke, Uwe; Seckl, Michael J; Arcaro, Alexandre (2009). AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001. Clinical cancer research, 15(4), pp. 1277-87. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-2166

Belyanskaya, Larisa L; Ziogas, Algirdas; Hopkins-Donaldson, Sally; Kurtz, Stefanie; Simon, Hans-Uwe; Stahel, Rolf; Zangemeister-Wittke, Uwe (2008). TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8. Lung cancer, 60(3), pp. 355-65. Amsterdam: Elsevier 10.1016/j.lungcan.2007.11.005

Hussain, Sajid; Plückthun, Andreas; Allen, Theresa M; Zangemeister-Wittke, Uwe (2007). Antitumor activity of an epithelial cell adhesion molecule targeted nanovesicular drug delivery system. Molecular cancer therapeutics, 6(11), pp. 3019-27. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0615

Giorgini, Simona; Trisciuoglio, Daniela; Gabellini, Chiara; Desideri, Marianna; Castellini, Laura; Colarossi, Cristina; Zangemeister-Wittke, Uwe; Zupi, Gabriella; Del Bufalo, Donatella (2007). Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression. Molecular cancer research, 5(8), pp. 761-71. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-07-0088

Huwiler, Andrea; Zangemeister-Wittke, Uwe (2007). Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy. Critical reviews in oncology, hematology, 63(2), pp. 150-9. Boca Raton, Fla.: Elsevier 10.1016/j.critrevonc.2007.04.010

Zangemeister-Wittke, Uwe (2007). Krebsbehandlung mit Antisensemolekülen. Onkologe, 13(2007), pp. 256-262. Heidelberg: Springer-Medizin-Verlag

Zangemeister-Wittke, Uwe (2007). Antisense molecules for targeted cancer therapy. Onkologe, 13(3), pp. 256-262. Springer-Medizin-Verlag 10.1007/s00761-006-1170-z

Zangemeister-Wittke, Uwe; Huwiler, Andrea (2006). Antisense targeting of Mcl-1 has therapeutic potential in gastric cancer. Cancer biology & therapy, 5(10), pp. 1355-1356. Georgetown, Tex.: Landes Bioscience 10.4161/cbt.5.10.3488

Hussain, Sajid; Plückthun, Andreas; Allen, Theresa M; Zangemeister-Wittke, Uwe (2006). Chemosensitization of carcinoma cells using epithelial cell adhesion molecule-targeted liposomal antisense against bcl-2/bcl-xL. Molecular cancer therapeutics, 5(12), pp. 3170-80. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-06-0412

Mousavi-Shafaei, Parisa; Ziaee, Abed-Ali; Azizi, Ebrahim; Zangemeister-Wittke, Uwe (2006). Antisense-mediated melanoma inhibitor of apoptosis protein downregulation sensitizes G361 melanoma cells to cisplatin. Anti-cancer drugs, 17(9), pp. 1031-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.cad.0000231474.77159.e3

Kubetzko, Susanne; Balic, Ela; Waibel, Robert; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2006). PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targeting. Journal of biological chemistry, 281(46), pp. 35186-201. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M604127200

Hopkins-Donaldson, Sally; Belyanskaya, Larisa L; Simões-Wüst, Ana Paula; Sigrist, Brigitte; Kurtz, Stefanie; Zangemeister-Wittke, Uwe; Stahel, Rolf (2006). p53-induced apoptosis occurs in the absence of p14(ARF) in malignant pleural mesothelioma. Neoplasia, 8(7), pp. 551-9. New York, N.Y.: Nature America 10.1593/neo.06148

Wacheck, V; Zangemeister-Wittke, Uwe (2006). Antisense molecules for targeted cancer therapy. Critical reviews in oncology, hematology, 59(1), pp. 65-73. Boca Raton, Fla.: Elsevier 10.1016/j.critrevonc.2005.10.004

Yamanaka, Kazuki; Rocchi, Palma; Miyake, Hideaki; Fazli, Ladan; So, Alan; Zangemeister-Wittke, Uwe; Gleave, Martin E (2006). Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes. BJU international, 97(6), pp. 1300-8. Oxford: Blackwell Science 10.1111/j.1464-410X.2006.06147.x

Zbären, Noemi

Zbären, Noemi; Brigger, Daniel; Bachmann, Daniel; Helbling, Arthur; Jörg, Lukas; Horn, Michael; Schmid, Johannes M; Hoffmann, Hans Jürgen; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). A novel functional mast cell assay for the detection of allergies. The Journal of allergy and clinical immunology, 149(3), 1018-1030.e11. Elsevier 10.1016/j.jaci.2021.08.006

Bachmeier-Zbären, Noemi; Kinet, Jean-Pierre; Kaufmann, Thomas; Eggel, Alexander (2022). Mast cell activation test (In Press). In: Reference Module in Food Science. Elsevier 10.1016/B978-0-323-96018-2.00032-8

Zhang, Lingli

Urtz, Nicole; Gaertner, Florian; von Bruehl, Marie-Luise; Chandraratne, Sue; Rahimi, Faridun; Zhang, Lingli; Orban, Mathias; Barocke, Verena; Beil, Johannes; Schubert, Irene; Lorenz, Michael; Legate, Kyle R; Huwiler, Andrea; Pfeilschifter, Josef M; Beerli, Christian; Ledieu, David; Persohn, Elke; Billich, Andreas; Baumruker, Thomas; Mederos y Schnitzler, Michael; ... (2015). Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. Circulation research, 117(4), pp. 376-387. Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.115.306901

Zhang, Yang

Rossi Sebastiano, Matteo; Pozzato, Chiara; Saliakoura, Maria; Zhang, Yang; Peng, Ren-Wang; Galiè, Mirco; Oberson, Kevin; Simon, Hans-Uwe; Karamitopoulou, Evanthia; Konstantinidou, Georgia (2020). ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Science Advances, 6(44), pp. 1-15. American Association for the Advancement of Science 10.1126/sciadv.abb9200

Zhao, Liang

Yang, Zhang; Liang, Shun-Qing; Saliakoura, Maria; Yang, Haitang; Vassella, Erik; Konstantinidou, Georgia; Tschan, Mario; Hegedüs, Balazs; Zhao, Liang; Gao, Yanyun; Xu, Duo; Deng, Haibin; Marti, Thomas M; Kocher, Gregor J; Wang, Wenxiang; Schmid, Ralph A; Peng, Ren-Wang (2021). Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS-mutant cancer. EMBO molecular medicine, 13(9), e13193. EMBO Press 10.15252/emmm.202013193

Ziemiecki, Andrew

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Zinkernagel, Martin Sebastian

Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

Zlobec, Inti

Liu, He; He, Zhaoyue; Germič, Nina; Ademi, Hyrijie; Frangež, Živa; Felser, Andrea; Peng, Shuang; Riether, Carsten; Djonov, Valentin; Nuoffer, Jean-Marc; Bovet, Cédric; Mlinarič-Raščan, Irena; Zlobec, Inti; Fiedler, Georg; Perren, Aurel; Simon, Hans-Uwe (2020). ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell death and differentiation, 27(6), pp. 1965-1980. Springer Nature 10.1038/s41418-019-0476-5

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Zumkehr, Béatrice

Brügger, Melanie; Démoulins, Thomas; Barut, G. Tuba; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Mehinagic, Kemal; Haas, Quentin; Schögler, Aline; Rameix-Welti, Marie-Anne; Eléouët, Jean-François; Moehrlen, Ueli; Marti, Thomas M.; Schmid, Ralph A.; Summerfield, Artur; Posthaus, Horst; Ruggli, Nicolas; Hall, Sean R. R.; Alves, Marco P. (2021). Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection. PLoS pathogens, 17(7), e1009789. Public Library of Science 10.1371/journal.ppat.1009789

Zwahlen, Marcel

Schoepfer, Alain M; Simko, Audrey; Bussmann, Christian; Safroneeva, Ekaterina; Zwahlen, Marcel; Greuter, Thomas; Biedermann, Luc; Vavricka, Stephan; Godat, Sébastien; Reinhard, Antoine; Saner, Catherine; Maye, Hugo; Sempoux, Christine; Brunel, Christophe; Blanchard, Carine; Simon, Dagmar; Simon, Hans-Uwe; Straumann, Alex (2018). Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms. American journal of gastroenterology, 113(3), pp. 348-357. Nature 10.1038/ajg.2017.493

Hruz, Petr; Straumann, Alex; Bussmann, Christian; Heer, Pius; Simon, Hans-Uwe; Zwahlen, Marcel; Beglinger, Christoph; Schoepfer, Alain M (2011). Escalating incidence of eosinophilic esophagitis: a 20-year prospective, population-based study in Olten County, Switzerland. Journal of allergy and clinical immunology, 128(6), 1349-1350.e5. St. Louis, Mo.: Mosby 10.1016/j.jaci.2011.09.013

Zwicky, Caroline

Vassina, Ekatherina M; Yousefi, Shida; Simon, Dagmar; Zwicky, Caroline; Conus, Sébastien; Simon, Hans-Uwe (2006). cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. European journal of immunology, 36(7), pp. 1975-84. Weinheim: Wiley-VCH 10.1002/eji.200635943

Zysset, Daniel

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Zysset, Denise Corinne

Thormann, Kathrin; Lüthi, Anne-Sophie; Deniau, Felix; Heider, Anja; Cazzaniga, Simone; Radonjic-Hoesli, Susanne; Lehmann, Mathias; Schlapbach, Christoph; Herzog, Elio L; Kreuzer, Marco; Zinkernagel, Martin S; Akdis, Cezmi A; Zysset, Denise C; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab-associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation. (In Press). Allergy Wiley-Blackwell 10.1111/all.16045

de Graauw, Elisabeth Louisa Maria

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

von Däniken, Sandro Urs

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

von Garnier, Christophe

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 1-8. Hogrefe 10.1024/1661-8157/a003250

Leuppi, Jörg D; Schmid-Grendelmeier, Peter; Rothe, Thomas; von Garnier, Christophe; Simon, Hans-Uwe; Schuoler, Claudio; Pendl, Gunther; Solèr, Markus (2019). [Benralizumab: Targeting the IL-5 Receptor in Severe Eosinophilic Asthma]. Praxis, 108(7), pp. 469-476. Hogrefe 10.1024/1661-8157/a003222

von Gunten, S; Marsland, B J; von Garnier, C; Simon, D (2012). Update in clinical allergy and immunology. Allergy, 67(12), pp. 1491-500. Oxford: Wiley-Blackwell 10.1111/all.12067

von Gunten, Stephan

Mehta, Akul Y; Tilton, Catherine A; Muerner, Lukas; Gunten, Stephan; Heimburg-Molinaro, Jamie; Cummings, Richard D (2024). Reusable glycan microarrays using a microwave assisted wet-erase (MAWE) process. Glycobiology, 34(2) Oxford University Press 10.1093/glycob/cwad091

Plattner, Kevin; Sousa Augusto, Gilles; Muerner, Lukas; von Gunten, Stephan; Jörg, Lukas; Engeroff, Paul; Bachmann, Martin F; Vogel, Monique (2023). IgE glycosylation is essential for the function of omalizumab. Allergy, 78(9), pp. 2546-2549. Wiley 10.1111/all.15748

Démoulins, Thomas; Schulze, Kai; Ebensen, Thomas; Techakriengkrai, Navapon; Nedumpun, Teerawut; Englezou, Pavlos C; Gerber, Markus; Hlushchuk, Ruslan; Toledo, Darien; Djonov, Valentin; von Gunten, Stephan; McCullough, Kenneth C; Liniger, Matthias; Guzmán, Carlos A; Suradhat, Sanipa; Ruggli, Nicolas (2023). Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases. Nanomedicine : nanotechnology, biology, and medicine, 49(102655), p. 102655. Elsevier 10.1016/j.nano.2023.102655

Zhu, Cui; Potenza, Duilio M; Yang, Yang; Ajalbert, Guillaume; Mertz, Kirsten D; von Gunten, Stephan; Ming, Xiu-Fen; Yang, Zhihong (2023). Role of pulmonary epithelial arginase-II in activation of fibroblasts and lung inflammaging. Aging cell, 22(4), e13790. Wiley 10.1111/acel.13790

Almizraq, Ruqayyah J; Frias Boligan, Kayluz; Lewis, Bonnie J B; Cen, Selena; Whetstone, Heather; Spirig, Rolf; Käsermann, Fabian; Campbell, Ian K; von Gunten, Stephan; Branch, Donald R (2023). Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis. Pharmacology, 108(2), pp. 176-187. Karger 10.1159/000528780

von Gunten, Stephan; Schneider, Christoph; Imamovic, Lejla; Gorochov, Guy (2023). Antibody diversity in IVIG: Therapeutic opportunities for novel immunotherapeutic drugs. Frontiers in immunology, 14, p. 1166821. Frontiers Research Foundation 10.3389/fimmu.2023.1166821

von Achenbach, Caroline; Hevia Hernandez, Giselle; von Gunten, Stephan (2022). The Choice between Intravenous and Subcutaneous Immunoglobulins: Aspects for Consideration. Pharmacology, 107(11-12), pp. 556-563. Karger 10.1159/000527655

Wolf, Babette; Piksa, Mateusz; Beley, Isabelle; Patoux, Agnes; Besson, Thierry; Cordier, Valerie; Voedisch, Bernd; Schindler, Patrick; Stöllner, Daniela; Perrot, Ludovic; von Gunten, Stephan; Brees, Dominique; Kammüller, Michael (2022). Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity. Immunology, 166(3), pp. 380-407. Wiley-Blackwell 10.1111/imm.13481

Gorochov, Guy; von Gunten, Stephan (2022). Diversification of IgA Antibody Specificities by Mild Chemical Modification? Pharmacology, 107(7-8), pp. 339-340. Karger 10.1159/000524041

Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

Angata, Takashi; von Gunten, Stephan; Schnaar, Ronald L.; Varki, Ajit (2022). I-Type Lectins. In: Essentials of Glycobiology. Cold Spring Harbor Laboratory Press 10.1101/glycobiology.4e.35

Lünemann, Jan D; von Gunten, Stephan; Neumann, Harald (2021). Targeting sialylation to treat central nervous system diseases. Trends in Pharmacological Sciences, 42(12), pp. 998-1008. Elsevier 10.1016/j.tips.2021.09.002

Rollenske, Tim; Burkhalter, Sophie; Muerner, Lukas; von Gunten, Stephan; Lukasiewicz, Jolanta; Wardemann, Hedda; Macpherson, Andrew J. (2021). Parallelism of intestinal secretory IgA shapes functional microbial fitness. Nature, 598(7882), pp. 657-661. Springer Nature 10.1038/s41586-021-03973-7

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Cummings, Richard D; von Gunten, Stephan (2021). Targeting the Laminated Layer of Echinococcus multilocularis as a Potential Therapeutic Strategy. Pharmacology, 106(1-2), pp. 1-2. Karger 10.1159/000512769

Hugonnet, Marjolaine; Singh, Pushpita; Haas, Quentin; von Gunten, Stephan (2021). The Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology. Frontiers in immunology, 12, p. 799861. Frontiers Research Foundation 10.3389/fimmu.2021.799861

von Gunten, Stephan; Simon, Hans-Uwe (2020). Linking glucocorticoid-induced osteoporosis to osteoimmunology. Cell death & disease, 11(12), p. 1026. Nature Publishing Group 10.1038/s41419-020-03250-x

Yu, Yi; Ladeiras, Diogo; Xiong, Yuyan; Frias Boligan, Kayluz; Liang, Xiujie; von Gunten, Stephan; Hunger, Robert E.; Ming, Xiu-Fen; Yang, Zhihong (2020). Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. Journal of cellular physiology, 235(12), pp. 9997-10011. Wiley 10.1002/jcp.29814

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Luetscher, Ralph N D; McKitrick, Tanya R; Gao, Chao; Mehta, Akul Y; McQuillan, Alyssa M; Kardish, Robert; Frias Boligan, Kayluz; Song, Xuezheng; Lu, Lenette; Heimburg-Molinaro, Jamie; von Gunten, Stephan; Alter, Galit; Cummings, Richard D (2020). Unique repertoire of anti-carbohydrate antibodies in individual human serum. Scientific reports, 10(1), p. 15436. Springer Nature 10.1038/s41598-020-71967-y

von Gunten, Stephan (2020). Inflamm-Aging: Arginase-II as Stage Setter in Age-Related Adipose Tissue Inflammation. Pharmacology, 105(9-10), pp. 489-490. Karger 10.1159/000510515

Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Human IgA binds a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.20181635

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Correction: Human IgA bind a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.2018163501152020c

Boligan, Kayluz F.; Oechtering, Johanna; Keller, Christian W; Peschke, Benjamin; Rieben, Robert; Bovin, Nicolai; Kappos, Ludwig; Cummings, Richard D; Kuhle, Jens; von Gunten, Stephan; Lünemann, Jan D (2020). Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS. Neurology: Neuroimmunology and Neuroinflammation, 7(2) Wolters Kluwer Health 10.1212/NXI.0000000000000676

Spinetti, Thibaud; Meisel, Christian; von Gunten, Stephan; Schefold, Joerg C. (2020). Immune biomarker-based enrichment in sepsis trials. Critical care, 24(1), p. 58. BioMed Central 10.1186/s13054-020-2774-1

von Gunten, Stephan (2020). The Future of Pharmacology: Towards More Personalized Pharmacotherapy and Reverse Translational Research. Pharmacology, 105(1-2), pp. 1-2. Karger 10.1159/000505216

von Gunten, Stephan (2020). Secondary-Type Carbohydrate Modification as a Driver of Epithelial-Mesenchymal Transition and Features of Cancer Stem Cells. Pharmacology, 105(5-6), pp. 244-245. Karger 10.1159/000507003

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973

Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1

Leviatan Ben-Arye, Shani; Schneider, Christoph; Yu, Hai; Bashir, Salam; Chen, Xi; von Gunten, Stephan; Padler-Karavani, Vered (2019). Differential Recognition of Diet-Derived Neu5Gc-Neoantigens on Glycan Microarrays by Carbohydrate-Specific Pooled Human IgG and IgA Antibodies. Bioconjugate chemistry, 30(5), pp. 1565-1574. American Chemical Society 10.1021/acs.bioconjchem.9b00273

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Verschoor, Daniëlle; von Gunten, Stephan (2019). Allergy and Atopic Diseases: An Update on Experimental Evidence. International archives of allergy and immunology, 180(4), pp. 235-243. Karger 10.1159/000504439

Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Stanczak, Michal A; Siddiqui, Shoib S; Trefny, Marcel P; Thommen, Daniela S; Frias Boligan, Kayluz; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael S; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghan; Amos, Christopher I; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E; Varki, Ajit; ... (2018). Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells. Journal of clinical investigation, 128(11), pp. 4912-4923. American Society for Clinical Investigation 10.1172/JCI120612

Adams, Olivia Joan; Stanczak, Michal A; von Gunten, Stephan; Läubli, Heinz (2018). Targeting sialic acid-Siglec interactions to reverse immune suppression in cancer. Glycobiology, 28(9), pp. 640-647. Oxford University Press 10.1093/glycob/cwx108

Haas, Quentin; Simillion, Cedric André Marie; von Gunten, Stephan (2018). A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future? Frontiers in oncology, 8, p. 68. Frontiers Research Foundation 10.3389/fonc.2018.00068

Adams, Olivia Joan; von Gunten, Stephan (2018). Recent Advances in Experimental Allergy. International archives of allergy and immunology, 177(4), pp. 281-289. Karger 10.1159/000494440

Späth, Peter Julius; Schneider, Christoph; von Gunten, Stephan (2017). Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations. Archivum immunologiae et therapiae experimentalis, 65(3), pp. 215-231. Springer 10.1007/s00005-016-0422-x

Frias Boligan, Kayluz; von Gunten, Stephan (2017). Innate lymphoid cells in asthma: cannabinoids on the balance. Allergy, 72(6), pp. 839-841. Wiley-Blackwell 10.1111/all.13145

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Kouskoura, Thaleia; Katsaros, Christos; von Gunten, Stephan (2017). The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM). Frontiers in physiology, 8(67), p. 67. Frontiers Research Foundation 10.3389/fphys.2017.00067

Schneider, Christoph; Illi, Marlies; Lötscher, Marius; Wehrli, Marc; von Gunten, Stephan (2017). Isolation of Antibodies from Human Plasma, Saliva, Breast Milk, and Gastrointestinal Fluid. Methods in molecular biology, 1643, pp. 23-31. Springer 10.1007/978-1-4939-7180-0_3

Quast, Isaak; Keller, Christian W; Weber, Patrick; Schneider, Christoph; von Gunten, Stephan; Lünemann, Jan D (2016). Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation. Journal of neuroinflammation, 13, p. 42. BioMed Central 10.1186/s12974-016-0506-x

(2016). Protein-carbohydrate interactions in the human immune system (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Schorer, Myriam Fabiola; Simon, Dagmar (2016). Innate immune system crosstalk: Eosinophils mediate immune modulation of dendritic cells through exosomes as shuttle vectors of miRNA (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Djoumerska-Alexieva, Iglika; Roumenina, Lubka; Pashov, Anastas; Dimitrov, Jordan; Hadzhieva, Maya; Lindig, Sandro; Voynova, Elisaveta; Dimitrova, Petya; Ivanovska, Nina; Bockmeyer, Clemens; Stefanova, Zvetanka; Fitting, Catherine; Bläss, Markus; Claus, Ralf; von Gunten, Stephan; Kaveri, Srini; Cavaillon, Jean-Marc; Bauer, Michael; Vassilev, Tchavdar (2015). Intravenous Immunoglobulin with Enhanced Polyspecificity Improves Survival in Experimental Sepsis and Aseptic Systemic Inflammatory Response Syndromes. Molecular medicine, 21(1), p. 1. Feinstein Institute for Medical Research 10.2119/molmed.2014.00224

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Cortinas-Elizondo, F.; von Gunten, Stephan (2015). MicroRNA-155: microtuning the allergic concert. Allergy, 70(9), pp. 1035-1036. Wiley-Blackwell 10.1111/all.12673

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/jimmunol.1400028

von Gunten, Stephan (2014). Protein-glycan interactions as targets of intravenous/subcutaneous immunoglobulin (IVIg/SCIg) preparations. Clinical and experimental immunology, 178(S1), pp. 151-152. Blackwell Scientific Publications 10.1111/cei.12550

Frias Boligan, Kayluz; Mesa, Circe; Fernandez, Luis Enrique; von Gunten, Stephan (2014). Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense. Cellular and molecular life sciences, 72(7), pp. 1231-1248. Springer 10.1007/s00018-014-1799-5

Stowell, Sean R.; Arthur, Connie M.; Mc Bride, Ryan; Berger, Oren; Razi, Nahid; Heimberg-Molinaro, Jamie; Rodrigues, Lilian C.; Gourdine, Jean-Philippe; Noll, Alexander J.; von Gunten, Stephan; Smith, David F.; Knirel, Yuriy A.; Paulson, James C.; Cummings, Richard D. (2014). Microbial glycan microarrays define key features of host-microbial interactions. Nature Chemical Biology, 10(6), pp. 470-476. Nature Publishing Group 10.1038/nchembio.1525

von Gunten, Stephan (2014). Targeting Siglecs: Neue potenzielle Strategien zur Immuntherapie entzündlicher oder maligner Erkrankungen. Leading Opinions. Hämatologie & Onkologie(2), pp. 34-36. Universimed

von Gunten, Stephan; Shoenfeld, Yehuda; Blank, Miri; Branch, Donald R.; Vassoöev, Tchavdar; Käsermann, Fabian; Bayy, Jagadeesh; Kaveri, Srini; Simon, Hans-Uwe (2014). IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist. Nature reviews - immunology, 14(5), pp. 349-350. Nature Publishing Group 10.1038/nri3401-c1

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899

von Gunten, Stephan; Wehrli, Marc; Simon, Hans-Uwe (2013). Cell death in immune thrombocytopenia: novel insights and perspectives. Seminars in hematology, 1(50), pp. 109-115. W.B. Saunders 10.1053/j.seminhematol.2013.03.016

Démoulins, Thomas; Bassi, Isabelle; Thomann-Harwood, Lisa; Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan; Mc Cullogh, Kenneth C (2013). Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells. Nanomedicine-Nanotechnology Biology and Medicine, 9(6), pp. 806-817. Elsevier 10.1016/j.nano.2013.01.002

von Gunten, Stephan; Schorer, Myriam Fabiola; Kollarik, M.; Beisswenger, C.; Lepper, P. M. (2013). Mechanisms and potential therapeutic targets in allergic inflammation: recent insights. Allergy, 68(12), pp. 1487-1498. Wiley-Blackwell 10.1111/all.12312

North, Simon J; von Gunten, Stephan; Antonopoulos, Aristotelis; Trollope, Alana; MacGlashan, Donald W; Jang-Lee, Jihye; Dell, Anne; Metcalfe, Dean D; Kirshenbaum, Arnold S; Bochner, Bruce S; Haslam, Stuart M (2012). Glycomic analysis of human mast cells, eosinophils and basophils. Glycobiology, 22(1), pp. 12-22. Oxford: Oxford University Press 10.1093/glycob/cwr089

von Gunten, Stephan; Kaufmann, Thomas (2012). Glucocorticoids 'on air'. Allergy, 67(2), pp. 144-6. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02778.x

von Gunten, S; Marsland, B J; von Garnier, C; Simon, D (2012). Update in clinical allergy and immunology. Allergy, 67(12), pp. 1491-500. Oxford: Wiley-Blackwell 10.1111/all.12067

von Gunten, Stephan; Simon, Hans-Uwe (2012). Granulocyte death regulation by naturally occurring autoantibodies. Advances in experimental medicine and biology, 750, pp. 157-172. Wien: Springer

Schaub, A; von Gunten, S; Vogel, M; Wymann, S; Rüegsegger, M; Stadler, B M; Spycher, M; Simon, H-U; Miescher, S (2011). Dimeric IVIG contains natural anti-Siglec-9 autoantibodies and their anti-idiotypes. Allergy, 66(8), pp. 1030-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02579.x

Casulli, Sarah; Topçu, Selma; Fattoum, Lakhdar; von Gunten, Stephan; Simon, Hans-Uwe; Teillaud, Jean-Luc; Bayry, Jagadeesh; Kaveri, Srini V.; Elbim, Carole (2011). A differential concentration-dependent effect of IVIg on neutrophil functions: relevance for anti-microbial and anti-inflammatory mechanisms. PLoS ONE, 6(10), e26469. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026469

Grader-Beck, Thomas; Boin, Francesco; von Gunten, Stephan; Smith, David; Rosen, Antony; Bochner, Bruce S (2011). Antibodies recognising sulfated carbohydrates are prevalent in systemic sclerosis and associated with pulmonary vascular disease. Annals of the rheumatic diseases, 70(12), pp. 2218-24. London: BMJ Publishing Group 10.1136/ard.2011.153130

Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan (2011). Targeting siglecs--a novel pharmacological strategy for immuno- and glycotherapy. Biochemical pharmacology, 82(4), pp. 323-32. New York, N.Y.: Elsevier 10.1016/j.bcp.2011.05.018

von Gunten, Stephan; Simon, Hans-Uwe (2010). Cell death modulation by intravenous immunoglobulin. Journal of clinical immunology, 30 Suppl 1, S24-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10875-010-9411-8

von Gunten, Stephan; Smith, David F; Cummings, Richard D; Riedel, Stefan; Miescher, Sylvia; Schaub, Alexander; Hamilton, Robert G; Bochner, Bruce S (2009). Intravenous immunoglobulin contains a broad repertoire of anticarbohydrate antibodies that is not restricted to the IgG2 subclass. Journal of allergy and clinical immunology, 123(6), 1268-76.e15. St. Louis, Mo.: Mosby 10.1016/j.jaci.2009.03.013

von Gunten, Stephan; Bochner, Bruce S (2009). Expression and Function of Siglec-8 in Human Eosinophils, Basophils, and Mast Cells. In: Pawankar, Ruby; Holgate, Stephen T; Rosenwasser, Lanny J (eds.) Allergy Frontiers: Classification and Pathomechanisms. Allergy Frontiers: Vol. 2 (pp. 297-313). Japan: Springer 10.1007/978-4-431-88315-9_19

Yokoi, Hidenori; Choi, Oksoon H; Hubbard, Walter; Lee, Hyun-Sil; Canning, Brendan J; Lee, Hyun H; Ryu, Seung-Duk; von Gunten, Stephan; Bickel, Carol A; Hudson, Sherry A; Macglashan, Donald W; Bochner, Bruce S (2008). Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement. Journal of allergy and clinical immunology, 121(2), 499-505.e1. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.10.004

von Gunten, Stephan; Bochner, Bruce S (2008). Basic and clinical immunology of Siglecs. Annals of the New York Academy of Sciences, 1143, pp. 61-82. Boston, Mass.: Blackwell 10.1196/annals.1443.011

von Gunten, Stephan; Vogel, Monique; Schaub, Alexander; Stadler, Beda M; Miescher, Sylvia; Crocker, Paul R; Simon, Hans-Uwe (2007). Intravenous immunoglobulin preparations contain anti-Siglec-8 autoantibodies. Journal of allergy and clinical immunology, 119(4), pp. 1005-11. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.01.023

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